Protein

KWMTBOMO04296

Length
1,364 amino acids

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1364

Detailed signature matches

  1. Family IPR000115
    Phosphoribosylglycinamide synthetase
    1. TIGR00877
    2. MF_00138 (GARS)
  2. Family IPR004733
    Phosphoribosylformylglycinamidine cyclo-ligase
    1. cd02196 (PurM)
    2. TIGR00878
    3. MF_00741 (AIRS)
  3. Family IPR004607
    Phosphoribosylglycinamide formyltransferase
    1. TIGR00639
    2. cd08645 (FMT_core_GART)
    3. MF_01930 (PurN)
  4. Domain IPR016185
    Pre-ATP-grasp domain
    1. SSF52440 (PreATP-gr...)
    2. G3DSA:3.40.50.20
  5. Domain IPR020562
    Phosphoribosylglycinamide synthetase, N-terminal
    1. PF02844 (GARS_N)
  6. Domain IPR011761
    ATP-grasp fold
    1. PS50975 (ATP_GRASP)
  7. Domain IPR020561
    Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
    1. PF01071 (GARS_A)
  8. Domain IPR013815
    ATP-grasp fold, subdomain 1
    1. G3DSA:3.30.14...
  9. Domain IPR013816
    ATP-grasp fold, subdomain 2
    1. G3DSA:3.30.47...
  10. Domain IPR011054
    Rudiment single hybrid motif
    1. SSF51246 (Rudiment ...)
  11. Domain IPR020560
    Phosphoribosylglycinamide synthetase, C-domain
    1. SM01210 (GARS_C_2)
    2. G3DSA:3.90.60...
    3. PF02843 (GARS_C)
  12. Domain IPR016188
    PurM-like, N-terminal domain
    1. G3DSA:3.30.13...
    2. PF00586 (AIRS)
  13. Domain IPR010918
    AIR synthase-related protein, C-terminal domain
    1. PF02769 (AIRS_C)
    2. G3DSA:3.90.65...
    3. SSF56042 (PurM C-te...)
  14. Domain IPR002376
    Formyl transferase, N-terminal
    1. G3DSA:3.40.50...
    2. SSF53328 (Formyltra...)
    3. PF00551 (Formyl_tra...)
  15. SITE IPR020559
    Phosphoribosylglycinamide synthetase, conserved site
    1. PS00184 (GARS)
  16. SITE IPR001555
    Phosphoribosylglycinamide formyltransferase, active site
    1. PS00373 (GART)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SM01209 (GARS_A_3)
  2. SSF55326 (PurM N-te...)
  3. SSF56059 (Glutathio...)

Residue annotation

  1. dimerization inter...
  2. putative ATP bindi...
  3. dimerization inter...
  4. putative ATP bindi...
  5. active site cd08645
  6. substrate binding ...
  7. cosubstrate bindin...
  8. catalytic site cd0...

GO term prediction

Biological Process

GO:0006189 'de novo' IMP biosynthetic process
GO:0009058 biosynthetic process
GO:0009113 purine nucleobase biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0004637 phosphoribosylamine-glycine ligase activity
GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004644 phosphoribosylglycinamide formyltransferase activity
GO:0005524 ATP binding
GO:0016742 hydroxymethyl-, formyl- and related transferase activity
GO:0046872 metal ion binding

Cellular Component

GO:0005737 cytoplasm