KWMTBOMO04268

Protein

Length

596 amino acids

Protein family membership

Sodium:neurotransmitter symporter (IPR000175)

Domains and repeats

None predicted.

Detailed signature matches

IPR000175

Sodium:neurotransmitter symporter
1. PS50267 (NA_NEUROTR...)
  
  46 - 569
  
  PROSITE profiles
  PS50267 (NA_NEUROTRAN_SYMP_3)
2. PR00176 (NANEUSMPORT)
  
  55 - 76
  
  PRINTS
  PR00176 (NANEUSMPORT)
  
  465 - 485
  
  PRINTS
  PR00176 (NANEUSMPORT)
  
  84 - 103
  
  PRINTS
  PR00176 (NANEUSMPORT)
  
  128 - 154
  
  PRINTS
  PR00176 (NANEUSMPORT)
  
  330 - 350
  
  PRINTS
  PR00176 (NANEUSMPORT)
  
  505 - 525
  
  PRINTS
  PR00176 (NANEUSMPORT)
  
  248 - 265
  
  PRINTS
  PR00176 (NANEUSMPORT)
  
  384 - 403
  
  PRINTS
  PR00176 (NANEUSMPORT)
3. PF00209 (SNF)
  
  47 - 565
  
  Pfam
  PF00209 (SNF)
4. PS00610 (NA_NEUROTR...)
  
  71 - 85
  
  PROSITE patterns
  PS00610 (NA_NEUROTRAN_SYMP_1)

no IPR

Unintegrated signatures

SSF161070 (SNF-like)

47 - 564

SUPERFAMILY
SSF161070 (SNF-like)
cd11497 (SLC6sbd_SE...)

47 - 575

CDD
cd11497 (SLC6sbd_SERT-like)
mobidb-lite (disord...)

1 - 34

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Na binding site 2 ...

62G

Na binding site 2
62G, 65V, 401L, 404D, 405S
CDD
cd11497 (SLC6sbd_SERT-like)

65V

Na binding site 2
62G, 65V, 401L, 404D, 405S
CDD
cd11497 (SLC6sbd_SERT-like)

401L

Na binding site 2
62G, 65V, 401L, 404D, 405S
CDD
cd11497 (SLC6sbd_SERT-like)

404D

Na binding site 2
62G, 65V, 401L, 404D, 405S
CDD
cd11497 (SLC6sbd_SERT-like)

405S

Na binding site 2
62G, 65V, 401L, 404D, 405S
CDD
cd11497 (SLC6sbd_SERT-like)
putative substrate...

63F

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

64A

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

66D

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

67L

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

68G

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

69N

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

144Y

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

303F

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

304S

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

309F

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

311T

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

405S

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

408G

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)

409G

putative substrate binding site 1
63F, 64A, 66D, 67L, 68G, 69N, 144Y, 303F, 304S, 309F, 311T, 405S, 408G, 409G
CDD
cd11497 (SLC6sbd_SERT-like)
Na binding site 1 ...

64A

Na binding site 1
64A, 69N, 304S, 336N
CDD
cd11497 (SLC6sbd_SERT-like)

69N

Na binding site 1
64A, 69N, 304S, 336N
CDD
cd11497 (SLC6sbd_SERT-like)

304S

Na binding site 1
64A, 69N, 304S, 336N
CDD
cd11497 (SLC6sbd_SERT-like)

336N

Na binding site 1
64A, 69N, 304S, 336N
CDD
cd11497 (SLC6sbd_SERT-like)
putative substrate...

71W

putative substrate binding site 2
71W, 72R, 143Y, 147I, 150W, 370P, 374F
CDD
cd11497 (SLC6sbd_SERT-like)

72R

putative substrate binding site 2
71W, 72R, 143Y, 147I, 150W, 370P, 374F
CDD
cd11497 (SLC6sbd_SERT-like)

143Y

putative substrate binding site 2
71W, 72R, 143Y, 147I, 150W, 370P, 374F
CDD
cd11497 (SLC6sbd_SERT-like)

147I

putative substrate binding site 2
71W, 72R, 143Y, 147I, 150W, 370P, 374F
CDD
cd11497 (SLC6sbd_SERT-like)

150W

putative substrate binding site 2
71W, 72R, 143Y, 147I, 150W, 370P, 374F
CDD
cd11497 (SLC6sbd_SERT-like)

370P

putative substrate binding site 2
71W, 72R, 143Y, 147I, 150W, 370P, 374F
CDD
cd11497 (SLC6sbd_SERT-like)

374F

putative substrate binding site 2
71W, 72R, 143Y, 147I, 150W, 370P, 374F
CDD
cd11497 (SLC6sbd_SERT-like)

GO term prediction

Biological Process

GO:0006836 neurotransmitter transport

Molecular Function

GO:0005328 neurotransmitter:sodium symporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features