KWMTBOMO04229

Protein

Length

450 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
16 - 434
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 450

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  27 - 388
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  22 - 430
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  57 - 425
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  16 - 434
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

20 - 220

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

237 - 438

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

68L

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

71F

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

72F

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

75Y

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

79Q

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

80I

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

82A

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

83G

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

132Q

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

133G

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

136V

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

137P

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

140N

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

141T

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

144G

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

156G

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

157A

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

160Y

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

161S

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

167N

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

260N

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

263F

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

264W

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

267M

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

268T

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

271P

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

285N

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

289S

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

293Y

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

296M

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

300S

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

357I

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

358V

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

361H

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

372L

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

373L

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

376T

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

377N

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

380A

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

381N

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

384S

putative substrate translocation pore
68L, 71F, 72F, 75Y, 79Q, 80I, 82A, 83G, 132Q, 133G, 136V, 137P, 140N, 141T, 144G, 156G, 157A, 160Y, 161S, 167N, 260N, 263F, 264W, 267M, 268T, 271P, 285N, 289S, 293Y, 296M, 300S, 357I, 358V, 361H, 372L, 373L, 376T, 377N, 380A, 381N, 384S
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

KWMTBOMO04229

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component