KWMTBOMO04192

Protein

Length

493 amino acids

Protein family membership

Major facilitator, sugar transporter-like (IPR005828)

Domains and repeats

Domain
33 - 482
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 493

Detailed signature matches

IPR005828

Major facilitator, sugar transporter-like
1. PF00083 (Sugar_tr)
  
  91 - 482
  
  Pfam
  PF00083 (Sugar_tr)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  33 - 478
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  107 - 475
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  106 - 482
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

109 - 247

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

29 - 69

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

304 - 481

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

113Q

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

116L

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

117Q

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

120I

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

124S

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

125I

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

127F

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

128G

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

174T

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

175A

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

178M

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

179V

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

182F

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

183V

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

186M

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

198G

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

199C

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

202Q

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

203I

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

209H

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

313C

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

316I

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

317W

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

320T

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

321G

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

324F

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

338P

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

342V

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

346G

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

349Q

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

353N

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

401V

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

404T

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

405A

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

408A

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

412Y

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

413I

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

416S

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

427A

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

428L

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

431C

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

432S

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

435M

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

436R

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

439S

putative substrate translocation pore
113Q, 116L, 117Q, 120I, 124S, 125I, 127F, 128G, 174T, 175A, 178M, 179V, 182F, 183V, 186M, 198G, 199C, 202Q, 203I, 209H, 313C, 316I, 317W, 320T, 321G, 324F, 338P, 342V, 346G, 349Q, 353N, 401V, 404T, 405A, 408A, 412Y, 413I, 416S, 427A, 428L, 431C, 432S, 435M, 436R, 439S
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0022857 transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features