KWMTBOMO03998

Protein

Length

1,552 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
1 - 171
Nucleotide cyclase (IPR029787)
Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054)
271 - 444
Nucleotide cyclase (IPR029787)
Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054)
458 - 726
P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 200 400 600 800 1000 1200 1400 1552

Detailed signature matches

IPR029787

Nucleotide cyclase
1. SSF55073 (Nucleotid...)
  
  271 - 443
  
  SUPERFAMILY
  SSF55073 (Nucleotide cyclase)
  
  2 - 170
  
  SUPERFAMILY
  SSF55073 (Nucleotide cyclase)
IPR001054

Adenylyl cyclase class-3/4/guanylyl cyclase
1. PS50125 (GUANYLATE_...)
  
  1 - 134
  
  PROSITE profiles
  PS50125 (GUANYLATE_CYCLASE_2)
  
  361 - 398
  
  PROSITE profiles
  PS50125 (GUANYLATE_CYCLASE_2)
2. G3DSA:3.30.70...
  
  2 - 171
  
  GENE3D
  G3DSA:3.30.70.1230 (G3DSA:3.30.70.1230)
  
  283 - 444
  
  GENE3D
  G3DSA:3.30.70.1230 (G3DSA:3.30.70.1230)
3. PF00211 (Guanylate_cyc)
  
  2 - 171
  
  Pfam
  PF00211 (Guanylate_cyc)
  
  326 - 438
  
  Pfam
  PF00211 (Guanylate_cyc)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  458 - 726
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
2. G3DSA:3.40.50...
  
  460 - 631
  
  GENE3D
  G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

no IPR

Unintegrated signatures

Coil

1,525 - 1,545

COILS
Coil (Coil)
PF13191 (AAA_16)

460 - 635

Pfam
PF13191 (AAA_16)
cd07302 (CHD)

2 - 170

CDD
cd07302 (CHD)

272 - 441

CDD
cd07302 (CHD)

Residue annotation

metal binding site...

3D

metal binding site
3D, 53D
CDD
cd07302 (CHD)

53D

metal binding site
3D, 53D
CDD
cd07302 (CHD)
nucleotidyl bindin...

3D

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

4V

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

5S

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

6G

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

7Y

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

8T

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

49K

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

51S

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

52G

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

53D

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

56L

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

121V

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

122L

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

123F

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

127V

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

128E

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

131K

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

132A

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)

170K

nucleotidyl binding site
3D, 4V, 5S, 6G, 7Y, 8T, 49K, 51S, 52G, 53D, 56L, 121V, 122L, 123F, 127V, 128E, 131K, 132A, 170K
CDD
cd07302 (CHD)
dimer interface cd...

8T

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

26T

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

29L

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

30N

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

33L

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

37I

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

49K

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

50F

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

108L

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

111T

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

122L

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

123F

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

124G

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

125L

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

128E

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)

170K

dimer interface
8T, 26T, 29L, 30N, 33L, 37I, 49K, 50F, 108L, 111T, 122L, 123F, 124G, 125L, 128E, 170K
CDD
cd07302 (CHD)
nucleotidyl bindin...

277F

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

314K

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

316I

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

318F

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

319D

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

325L

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

385T

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

386V

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

387I

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

391V

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

392N

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

395A

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

396R

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)

431K

nucleotidyl binding site
277F, 314K, 316I, 318F, 319D, 325L, 385T, 386V, 387I, 391V, 392N, 395A, 396R, 431K
CDD
cd07302 (CHD)
dimer interface cd...

291I

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

294V

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

295N

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

298Y

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

302C

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

314K

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

315I

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

372Y

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

375V

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

386V

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

387I

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

388G

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

389A

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

392N

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)

431K

dimer interface
291I, 294V, 295N, 298Y, 302C, 314K, 315I, 372Y, 375V, 386V, 387I, 388G, 389A, 392N, 431K
CDD
cd07302 (CHD)
metal binding site...

319D

metal binding site
319D
CDD
cd07302 (CHD)

GO term prediction

Biological Process

GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction

Molecular Function

GO:0016849 phosphorus-oxygen lyase activity

Cellular Component