KWMTBOMO03871

Protein

Length

176 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
62 - 152
Histone-fold (IPR009072)
Transcription initiation factor TFIID, subunit 12 (IPR003228)

1 20 40 60 80 100 120 140 160 176

Detailed signature matches

IPR009072

Histone-fold
1. G3DSA:1.10.20.10
  
  68 - 142
  
  GENE3D
  G3DSA:1.10.20.10 (G3DSA:1.10.20.10)
2. SSF47113 (Histone-fold)
  
  70 - 142
  
  SUPERFAMILY
  SSF47113 (Histone-fold)
IPR003228

Transcription initiation factor TFIID, subunit 12
1. PF03847 (TFIID_20kDa)
  
  73 - 140
  
  Pfam
  PF03847 (TFIID_20kDa)
2. cd07981 (TAF12)
  
  71 - 142
  
  CDD
  cd07981 (TAF12)
3. PD012998
  
  62 - 152
  
  ProDom
  PD012998 (PD012998)

no IPR

Unintegrated signatures

mobidb-lite (disord...)

32 - 72

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

heterodimer interf...

71L

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

72L

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

76R

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

80L

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

83E

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

84V

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

98L

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

101L

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

102A

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

103D

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

105F

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

106I

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

107D

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

110L

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

111N

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

114C

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

117A

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

123P

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

125V

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

126E

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

127L

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

130V

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

131Q

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

134L

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

138W

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

140M

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)

142I

heterodimer interface
71L, 72L, 76R, 80L, 83E, 84V, 98L, 101L, 102A, 103D, 105F, 106I, 107D, 110L, 111N, 114C, 117A, 123P, 125V, 126E, 127L, 130V, 131Q, 134L, 138W, 140M, 142I
CDD
cd07981 (TAF12)
Heterotetramer int...

91D

Heterotetramer interface
91D, 93E, 94V, 97M, 100Q, 101L, 104D
CDD
cd07981 (TAF12)

93E

Heterotetramer interface
91D, 93E, 94V, 97M, 100Q, 101L, 104D
CDD
cd07981 (TAF12)

94V

Heterotetramer interface
91D, 93E, 94V, 97M, 100Q, 101L, 104D
CDD
cd07981 (TAF12)

97M

Heterotetramer interface
91D, 93E, 94V, 97M, 100Q, 101L, 104D
CDD
cd07981 (TAF12)

100Q

Heterotetramer interface
91D, 93E, 94V, 97M, 100Q, 101L, 104D
CDD
cd07981 (TAF12)

101L

Heterotetramer interface
91D, 93E, 94V, 97M, 100Q, 101L, 104D
CDD
cd07981 (TAF12)

104D

Heterotetramer interface
91D, 93E, 94V, 97M, 100Q, 101L, 104D
CDD
cd07981 (TAF12)

GO term prediction

Biological Process

GO:0006352 DNA-templated transcription, initiation

Molecular Function

GO:0046982 protein heterodimerization activity

Cellular Component

GO:0005669 transcription factor TFIID complex

Filter view on

Entry type

Status

Per-residue features