KWMTBOMO03691

Protein

Length

491 amino acids

Protein family membership

Phenylalanyl-tRNA synthetase, class IIc, alpha subunit (IPR004529)

Domains and repeats

Domain
204 - 480
Phenylalanyl-tRNA synthetase (IPR002319)
Domain
223 - 474
Aminoacyl-tRNA synthetase, class II (IPR006195)

1 50 100 150 200 250 300 350 400 450 491

Detailed signature matches

IPR004529

Phenylalanyl-tRNA synthetase, class IIc, alpha subunit
1. TIGR00468
  
  154 - 477
  
  TIGRFAMs
  TIGR00468 (TIGR00468)
IPR002319

Phenylalanyl-tRNA synthetase
1. PF01409 (tRNA-synt_2d)
  
  204 - 480
  
  Pfam
  PF01409 (tRNA-synt_2d)
IPR006195

Aminoacyl-tRNA synthetase, class II
1. PS50862 (AA_TRNA_LI...)
  
  223 - 474
  
  PROSITE profiles
  PS50862 (AA_TRNA_LIGASE_II)

no IPR

Unintegrated signatures

G3DSA:3.30.93...

142 - 482

GENE3D
G3DSA:3.30.930.10 (G3DSA:3.30.930.10)
SSF55681 (Class II ...)

204 - 477

SUPERFAMILY
SSF55681 (Class II aaRS and biotin synthetases)
cd00496 (PheRS_alph...)

219 - 477

CDD
cd00496 (PheRS_alpha_core)

Residue annotation

dimer interface cd...

219H

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

222L

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

225R

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

226S

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

233L

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

238T

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

239E

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

241P

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

242T

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

243N

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

261Q

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

266D

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

270T

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

271F

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

272F

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

273M

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

274S

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

275S

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

329M

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

341P

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

342Q

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

343K

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

347I

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

349K

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

351F

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

353N

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

361L

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

378L

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

379A

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

380D

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

382I

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

383T

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

401P

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

408E

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

409P

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

410S

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

412E

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

433R

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

434P

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

472V

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

474P

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

475K

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)

476V

dimer interface
219H, 222L, 225R, 226S, 233L, 238T, 239E, 241P, 242T, 243N, 261Q, 266D, 270T, 271F, 272F, 273M, 274S, 275S, 329M, 341P, 342Q, 343K, 347I, 349K, 351F, 353N, 361L, 378L, 379A, 380D, 382I, 383T, 401P, 408E, 409P, 410S, 412E, 433R, 434P, 472V, 474P, 475K, 476V
CDD
cd00496 (PheRS_alpha_core)
motif 1 cd00496

237F

motif 1
237F, 238T, 239E, 240M, 241P, 242T, 243N
CDD
cd00496 (PheRS_alpha_core)

238T

motif 1
237F, 238T, 239E, 240M, 241P, 242T, 243N
CDD
cd00496 (PheRS_alpha_core)

239E

motif 1
237F, 238T, 239E, 240M, 241P, 242T, 243N
CDD
cd00496 (PheRS_alpha_core)

240M

motif 1
237F, 238T, 239E, 240M, 241P, 242T, 243N
CDD
cd00496 (PheRS_alpha_core)

241P

motif 1
237F, 238T, 239E, 240M, 241P, 242T, 243N
CDD
cd00496 (PheRS_alpha_core)

242T

motif 1
237F, 238T, 239E, 240M, 241P, 242T, 243N
CDD
cd00496 (PheRS_alpha_core)

243N

motif 1
237F, 238T, 239E, 240M, 241P, 242T, 243N
CDD
cd00496 (PheRS_alpha_core)
active site cd00496

266D

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

267A

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

268H

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

321H

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

323T

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

326S

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

352R

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

354E

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

359T

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

360H

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

361L

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

364F

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

366Q

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

368E

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

404N

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

406Y

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

407T

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

425E

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

426I

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

427G

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

428N

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

429S

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

430G

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

451W

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

452G

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

453L

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

454S

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

457R

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)

468I

active site
266D, 267A, 268H, 321H, 323T, 326S, 352R, 354E, 359T, 360H, 361L, 364F, 366Q, 368E, 404N, 406Y, 407T, 425E, 426I, 427G, 428N, 429S, 430G, 451W, 452G, 453L, 454S, 457R, 468I
CDD
cd00496 (PheRS_alpha_core)
motif 2 cd00496

351F

motif 2
351F, 352R, 353N, 354E
CDD
cd00496 (PheRS_alpha_core)

352R

motif 2
351F, 352R, 353N, 354E
CDD
cd00496 (PheRS_alpha_core)

353N

motif 2
351F, 352R, 353N, 354E
CDD
cd00496 (PheRS_alpha_core)

354E

motif 2
351F, 352R, 353N, 354E
CDD
cd00496 (PheRS_alpha_core)
motif 3 cd00496

452G

motif 3
452G, 453L, 454S, 455L, 456E, 457R
CDD
cd00496 (PheRS_alpha_core)

453L

motif 3
452G, 453L, 454S, 455L, 456E, 457R
CDD
cd00496 (PheRS_alpha_core)

454S

motif 3
452G, 453L, 454S, 455L, 456E, 457R
CDD
cd00496 (PheRS_alpha_core)

455L

motif 3
452G, 453L, 454S, 455L, 456E, 457R
CDD
cd00496 (PheRS_alpha_core)

456E

motif 3
452G, 453L, 454S, 455L, 456E, 457R
CDD
cd00496 (PheRS_alpha_core)

457R

motif 3
452G, 453L, 454S, 455L, 456E, 457R
CDD
cd00496 (PheRS_alpha_core)

GO term prediction

Biological Process

GO:0006432 phenylalanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation

Molecular Function

GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm

Filter view on

Entry type

Status

Per-residue features