KWMTBOMO03164

Protein

Length

572 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)
- Multidrug resistance protein (IPR004734)

Domains and repeats

Domain
41 - 468
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 572

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  52 - 390
  
  Pfam
  PF07690 (MFS_1)
IPR004734

Multidrug resistance protein
1. TIGR00880
  
  116 - 255
  
  TIGRFAMs
  TIGR00880 (TIGR00880)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  45 - 468
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  46 - 462
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  41 - 80
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  115 - 466
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

280 - 463

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

37 - 80

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

115 - 263

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
mobidb-lite (disord...)

523 - 572

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

60Y

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

63I

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

64V

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

65P

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

67I

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

68P

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

119F

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

122K

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

123A

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

126Q

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

130N

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

131P

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

133S

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

134G

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

180S

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

181A

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

184D

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

185T

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

188L

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

189A

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

192A

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

205L

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

206G

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

209L

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

210A

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

216S

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

291M

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

294N

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

295V

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

298A

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

299F

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

302P

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

319I

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

323W

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

327F

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

330H

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

334V

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

383C

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

386I

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

387A

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

390D

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

394L

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

395P

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

398G

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

412I

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

413Y

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

416A

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

417D

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

420Y

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

421S

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

424Y

putative substrate translocation pore
60Y, 63I, 64V, 65P, 67I, 68P, 119F, 122K, 123A, 126Q, 130N, 131P, 133S, 134G, 180S, 181A, 184D, 185T, 188L, 189A, 192A, 205L, 206G, 209L, 210A, 216S, 291M, 294N, 295V, 298A, 299F, 302P, 319I, 323W, 327F, 330H, 334V, 383C, 386I, 387A, 390D, 394L, 395P, 398G, 412I, 413Y, 416A, 417D, 420Y, 421S, 424Y
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0015893 drug transport
GO:0055085 transmembrane transport

Molecular Function

GO:0015238 drug transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features