KWMTBOMO03144

Protein

Length

536 amino acids

Protein family membership

Major facilitator, sugar transporter-like (IPR005828)

Domains and repeats

Domain
48 - 532
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 500 536

Detailed signature matches

IPR005828

Major facilitator, sugar transporter-like
1. PF00083 (Sugar_tr)
  
  88 - 342
  
  Pfam
  PF00083 (Sugar_tr)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  64 - 532
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  91 - 527
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  48 - 354
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  385 - 528
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

323 - 533

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

65 - 262

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

105T

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

108T

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

109Y

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

112M

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

116A

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

117M

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

119W

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

120G

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

166F

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

167N

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

170F

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

171A

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

174I

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

175S

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

178A

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

190I

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

191L

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

194S

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

195L

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

201S

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

336M

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

339S

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

340N

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

343R

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

344L

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

347P

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

390T

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

394S

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

398G

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

401S

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

405Y

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

453L

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

456T

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

457A

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

460A

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

464S

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

465S

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

468V

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

479A

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

480M

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

483F

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

484L

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

487G

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

488R

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

491T

putative substrate translocation pore
105T, 108T, 109Y, 112M, 116A, 117M, 119W, 120G, 166F, 167N, 170F, 171A, 174I, 175S, 178A, 190I, 191L, 194S, 195L, 201S, 336M, 339S, 340N, 343R, 344L, 347P, 390T, 394S, 398G, 401S, 405Y, 453L, 456T, 457A, 460A, 464S, 465S, 468V, 479A, 480M, 483F, 484L, 487G, 488R, 491T
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0022857 transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features