KWMTBOMO03097

Protein

Length

331 amino acids

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Domains and repeats

Domain
65 - 317
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 300 331

Detailed signature matches

IPR002347

Short-chain dehydrogenase/reductase SDR
1. PF00106 (adh_short)
  
  72 - 263
  
  Pfam
  PF00106 (adh_short)
2. PR00080 (SDRFAMILY)
  
  219 - 238
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  146 - 157
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  199 - 207
  
  PRINTS
  PR00080 (SDRFAMILY)
3. PR00081 (GDHRDH)
  
  219 - 238
  
  PRINTS
  PR00081 (GDHRDH)
  
  193 - 209
  
  PRINTS
  PR00081 (GDHRDH)
  
  72 - 89
  
  PRINTS
  PR00081 (GDHRDH)
  
  146 - 157
  
  PRINTS
  PR00081 (GDHRDH)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  65 - 317
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
2. G3DSA:3.40.50...
  
  70 - 317
  
  GENE3D
  G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
IPR020904

Short-chain dehydrogenase/reductase, conserved site
1. PS00061 (ADH_SHORT)
  
  206 - 234
  
  PROSITE patterns
  PS00061 (ADH_SHORT)

no IPR

Unintegrated signatures

cd05339 (17beta-HSD...)

72 - 316

CDD
cd05339 (17beta-HSDXI-like_SDR_c)

Residue annotation

putative NAD(P) bi...

77G

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

79G

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

80H

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

81G

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

82M

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

101D

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

102I

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

103N

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

126C

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

127D

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

128V

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

154N

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

155A

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

156G

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

177V

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

204M

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

205S

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

206S

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

219Y

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

223K

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

254P

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

255Y

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

256I

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

257V

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

259T

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

260G

putative NAD(P) binding site
77G, 79G, 80H, 81G, 82M, 101D, 102I, 103N, 126C, 127D, 128V, 154N, 155A, 156G, 177V, 204M, 205S, 206S, 219Y, 223K, 254P, 255Y, 256I, 257V, 259T, 260G
CDD
cd05339 (17beta-HSDXI-like_SDR_c)
homodimer interfac...

131S

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

135K

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

167G

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

168E

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

171I

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

172R

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

175F

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

179V

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

180M

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

183L

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

184W

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

187Q

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

216L

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

217V

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

218P

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

220C

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

221A

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

224F

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

225A

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

228G

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

229L

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

231E

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

232A

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

233L

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

235E

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

236E

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

260G

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

261L

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

262C

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

304Y

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

305V

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

308F

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

312L

homodimer interface
131S, 135K, 167G, 168E, 171I, 172R, 175F, 179V, 180M, 183L, 184W, 187Q, 216L, 217V, 218P, 220C, 221A, 224F, 225A, 228G, 229L, 231E, 232A, 233L, 235E, 236E, 260G, 261L, 262C, 304Y, 305V, 308F, 312L
CDD
cd05339 (17beta-HSDXI-like_SDR_c)
active site cd05339

178N

active site
178N, 206S, 219Y, 223K
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

206S

active site
178N, 206S, 219Y, 223K
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

219Y

active site
178N, 206S, 219Y, 223K
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

223K

active site
178N, 206S, 219Y, 223K
CDD
cd05339 (17beta-HSDXI-like_SDR_c)
substrate binding ...

187Q

substrate binding site
187Q, 190L, 233L, 236E, 242R
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

190L

substrate binding site
187Q, 190L, 233L, 236E, 242R
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

233L

substrate binding site
187Q, 190L, 233L, 236E, 242R
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

236E

substrate binding site
187Q, 190L, 233L, 236E, 242R
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

242R

substrate binding site
187Q, 190L, 233L, 236E, 242R
CDD
cd05339 (17beta-HSDXI-like_SDR_c)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO03097

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component