KWMTBOMO02913

Protein

Length

167 amino acids

Protein family membership

6-pyruvoyl tetrahydropterin synthase/QueD family protein (IPR007115)

Domains and repeats

None predicted.

Detailed signature matches

IPR007115

6-pyruvoyl tetrahydropterin synthase/QueD family protein
1. PF01242 (PTPS)
  
  9 - 139
  
  Pfam
  PF01242 (PTPS)
2. TIGR00039
  
  7 - 140
  
  TIGRFAMs
  TIGR00039 (TIGR00039)
IPR022470

6-pyruvoyl tetrahydropterin synthase, cysteine active site
1. PS00987 (PTPS_1)
  
  38 - 48
  
  PROSITE patterns
  PS00987 (PTPS_1)
IPR022469

6-pyruvoyl tetrahydropterin synthase, histidine active site
1. PS00988 (PTPS_2)
  
  84 - 91
  
  PROSITE patterns
  PS00988 (PTPS_2)

no IPR

Unintegrated signatures

G3DSA:3.30.47...

5 - 140

GENE3D
G3DSA:3.30.479.10 (G3DSA:3.30.479.10)
SSF55620 (Tetrahydr...)

7 - 140

SUPERFAMILY
SSF55620 (Tetrahydrobiopterin biosynthesis enzymes-like)
cd00470 (PTPS)

6 - 140

CDD
cd00470 (PTPS)
mobidb-lite (disord...)

140 - 167

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

homohexamer interf...

6I

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

58V

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

59D

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

60P

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

61Q

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

62T

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

63G

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

64M

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

65V

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

66M

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

67N

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

68I

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

101T

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

102T

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

103E

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

104N

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

105V

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

106A

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

107I

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

138Y

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)

140G

homohexamer interface
6I, 58V, 59D, 60P, 61Q, 62T, 63G, 64M, 65V, 66M, 67N, 68I, 101T, 102T, 103E, 104N, 105V, 106A, 107I, 138Y, 140G
CDD
cd00470 (PTPS)
putative substrate...

8S

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

10I

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

12R

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

14T

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

49V

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

51L

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

53T

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

124H

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

125E

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

127K

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

129L

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

135H

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

137V

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)

139R

putative substrate stabilizing pore
8S, 10I, 12R, 14T, 49V, 51L, 53T, 124H, 125E, 127K, 129L, 135H, 137V, 139R
CDD
cd00470 (PTPS)
pterin binding sit...

19H

pterin binding site
19H, 21L, 38C, 44H, 46H, 84D, 85H, 102T, 103E
CDD
cd00470 (PTPS)

21L

pterin binding site
19H, 21L, 38C, 44H, 46H, 84D, 85H, 102T, 103E
CDD
cd00470 (PTPS)

38C

pterin binding site
19H, 21L, 38C, 44H, 46H, 84D, 85H, 102T, 103E
CDD
cd00470 (PTPS)

44H

pterin binding site
19H, 21L, 38C, 44H, 46H, 84D, 85H, 102T, 103E
CDD
cd00470 (PTPS)

46H

pterin binding site
19H, 21L, 38C, 44H, 46H, 84D, 85H, 102T, 103E
CDD
cd00470 (PTPS)

84D

pterin binding site
19H, 21L, 38C, 44H, 46H, 84D, 85H, 102T, 103E
CDD
cd00470 (PTPS)

85H

pterin binding site
19H, 21L, 38C, 44H, 46H, 84D, 85H, 102T, 103E
CDD
cd00470 (PTPS)

102T

pterin binding site
19H, 21L, 38C, 44H, 46H, 84D, 85H, 102T, 103E
CDD
cd00470 (PTPS)

103E

pterin binding site
19H, 21L, 38C, 44H, 46H, 84D, 85H, 102T, 103E
CDD
cd00470 (PTPS)

GO term prediction

Biological Process

GO:0006729 tetrahydrobiopterin biosynthetic process

Molecular Function

GO:0003874 6-pyruvoyltetrahydropterin synthase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO02913

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component