Protein

KWMTBOMO02530

Length
510 amino acids

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 510

Detailed signature matches

  1. Domain IPR000219
    Dbl homology (DH) domain
    1. SSF48065 (DBL homol...)
    2. PS50010 (DH_2)
    3. SM00325 (RhoGEF_3)
    4. G3DSA:1.20.90...
    5. PF00621 (RhoGEF)
  2. Domain IPR011993
    PH domain-like
    1. G3DSA:2.30.29.30
    2. SSF50729 (PH domain...)
  3. Domain IPR001849
    Pleckstrin homology domain
    1. PS50003 (PH_DOMAIN)
    2. SM00233 (PH_update)
  4. Domain IPR001452
    SH3 domain
    1. PF00018 (SH3_1)
    2. PS50002 (SH3)
    3. SSF50044 (SH3-domain)
    4. SM00326 (SH3_2)
  5. SITE IPR001331
    Guanine-nucleotide dissociation stimulator, CDC24, conserved site
    1. PS00741 (DH_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.30.30.40
  2. cd00160 (RhoGEF)
  3. cd11856 (SH3_p47pho...)
  4. mobidb-lite (disord...)

Residue annotation

  1. GTPase interaction...
  2. peptide ligand bin...

GO term prediction

Biological Process

GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction

Molecular Function

GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding

Cellular Component

None predicted.