Protein

KWMTBOMO02151

Length
962 amino acids

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
  4. Domain
1 100 200 300 400 500 600 700 800 900 962

Detailed signature matches

  1. Family IPR001631
    DNA topoisomerase I
    1. PR00416 (EUTPISMRASEI)
  2. Domain IPR008336
    DNA topoisomerase I, DNA binding, eukaryotic-type
    1. SSF56741 (Eukaryoti...)
    2. PF02919 (Topoisom_I_N)
  3. Domain IPR013030
    DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type
    1. G3DSA:2.170.1...
  4. Domain IPR013034
    DNA topoisomerase I, domain 1
    1. G3DSA:1.10.10.41
  5. Domain IPR013499
    DNA topoisomerase I, eukaryotic-type
    1. SM00435 (topeu)
  6. Domain IPR014711
    DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type
    1. G3DSA:3.90.15.10
  7. Domain IPR011010
    DNA breaking-rejoining enzyme, catalytic core
    1. SSF56349 (DNA break...)
  8. Domain IPR013500
    DNA topoisomerase I, catalytic core, eukaryotic-type
    1. cd00659 (Topo_IB_C)
    2. PF01028 (Topoisom_I)
  9. Domain IPR014727
    DNA topoisomerase I, catalytic core, alpha/beta subdomain
    1. G3DSA:1.10.13...
  10. Domain IPR025834
    Topoisomerase I C-terminal domain
    1. PF14370 (Topo_C_assoc)
  11. SITE IPR018521
    DNA topoisomerase I, active site
    1. PS00176 (TOPOISOMER...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. SSF46596 (Eukaryoti...)
  3. cd03488 (Topoisomer...)
  4. mobidb-lite (disord...)

Residue annotation

  1. DNA binding cd03488
  2. topo1 poison bindi...
  3. DNA binding site c...
  4. active site cd00659

GO term prediction

Biological Process

GO:0006265 DNA topological change

Molecular Function

GO:0003677 DNA binding
GO:0003917 DNA topoisomerase type I activity

Cellular Component

GO:0005694 chromosome