KWMTBOMO02001

Protein

Length

2,248 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
26 - 146
CUB domain (IPR000859)
641 - 685
PSI domain (IPR016201)
687 - 771
PSI domain (IPR016201)
933 - 986
PSI domain (IPR016201)
987 - 1,029
PSI domain (IPR016201)
1,031 - 1,073
PSI domain (IPR016201)
1,095 - 1,156
PSI domain (IPR016201)
1,157 - 1,198
EGF-like calcium-binding domain (IPR001881)
1,314 - 1,459
CUB domain (IPR000859)
1,551 - 1,646
Galactose oxidase, beta-propeller (IPR015916)
1,938 - 2,001
PSI domain (IPR016201)
2,067 - 2,127
PSI domain (IPR016201)
2,129 - 2,177
PSI domain (IPR016201)
Domain
145 - 173
EGF-like domain (IPR000742)
173 - 204
EGF-like domain (IPR000742)
211 - 267
Kelch-type beta propeller (IPR015915)
357 - 621
Kelch-type beta propeller (IPR015915)
1,157 - 1,198
EGF-like domain (IPR000742)
1,200 - 1,230
EGF-like domain (IPR000742)
1,276 - 1,312
EGF-like domain (IPR000742)
1,457 - 1,485
EGF-like domain (IPR000742)
1,485 - 1,521
EGF-like domain (IPR000742)
1,647 - 1,870
Kelch-type beta propeller (IPR015915)
Domain
1,152 - 1,283
Growth factor receptor cysteine-rich domain (IPR009030)
Domain
1,218 - 1,279
Laminin EGF domain (IPR002049)
1,280 - 1,334
Laminin EGF domain (IPR002049)
Repeat
1,095 - 1,156
Plexin repeat (IPR002165)
1,784 - 1,825
Kelch repeat type 1 (IPR006652)

1 500 1000 1500 2248

Detailed signature matches

IPR000859

CUB domain
1. SM00042 (CUB_2)
  
  35 - 144
  
  SMART
  SM00042 (CUB_2)
2. cd00041 (CUB)
  
  37 - 141
  
  CDD
  cd00041 (CUB)
3. PS01180 (CUB)
  
  32 - 144
  
  PROSITE profiles
  PS01180 (CUB)
  
  1,314 - 1,456
  
  PROSITE profiles
  PS01180 (CUB)
4. G3DSA:2.60.12...
  
  26 - 142
  
  GENE3D
  G3DSA:2.60.120.290 (G3DSA:2.60.120.290)
  
  1,359 - 1,459
  
  GENE3D
  G3DSA:2.60.120.290 (G3DSA:2.60.120.290)
5. PF00431 (CUB)
  
  32 - 141
  
  Pfam
  PF00431 (CUB)
6. SSF49854 (Spermadhe...)
  
  1,361 - 1,458
  
  SUPERFAMILY
  SSF49854 (Spermadhesin, CUB domain)
  
  31 - 146
  
  SUPERFAMILY
  SSF49854 (Spermadhesin, CUB domain)
IPR000742

EGF-like domain
1. PS50026 (EGF_3)
  
  1,485 - 1,521
  
  PROSITE profiles
  PS50026 (EGF_3)
  
  173 - 204
  
  PROSITE profiles
  PS50026 (EGF_3)
  
  1,157 - 1,198
  
  PROSITE profiles
  PS50026 (EGF_3)
2. SM00181 (egf_5)
  
  1,488 - 1,521
  
  SMART
  SM00181 (egf_5)
  
  1,457 - 1,485
  
  SMART
  SM00181 (egf_5)
  
  1,276 - 1,312
  
  SMART
  SM00181 (egf_5)
  
  1,160 - 1,198
  
  SMART
  SM00181 (egf_5)
  
  145 - 173
  
  SMART
  SM00181 (egf_5)
  
  176 - 204
  
  SMART
  SM00181 (egf_5)
  
  1,200 - 1,230
  
  SMART
  SM00181 (egf_5)
IPR015915

Kelch-type beta propeller
1. G3DSA:2.120.1...
  
  357 - 621
  
  GENE3D
  G3DSA:2.120.10.80 (G3DSA:2.120.10.80)
  
  1,647 - 1,870
  
  GENE3D
  G3DSA:2.120.10.80 (G3DSA:2.120.10.80)
  
  211 - 267
  
  GENE3D
  G3DSA:2.120.10.80 (G3DSA:2.120.10.80)
IPR016201

PSI domain
1. SM00423 (psinew7)
  
  687 - 771
  
  SMART
  SM00423 (psinew7)
  
  2,129 - 2,177
  
  SMART
  SM00423 (psinew7)
  
  987 - 1,029
  
  SMART
  SM00423 (psinew7)
  
  1,031 - 1,073
  
  SMART
  SM00423 (psinew7)
  
  1,095 - 1,156
  
  SMART
  SM00423 (psinew7)
  
  1,938 - 2,001
  
  SMART
  SM00423 (psinew7)
  
  641 - 685
  
  SMART
  SM00423 (psinew7)
  
  933 - 986
  
  SMART
  SM00423 (psinew7)
  
  2,067 - 2,127
  
  SMART
  SM00423 (psinew7)
IPR009030

Growth factor receptor cysteine-rich domain
1. SSF57184 (Growth fa...)
  
  1,152 - 1,283
  
  SUPERFAMILY
  SSF57184 (Growth factor receptor domain)
IPR001881

EGF-like calcium-binding domain
1. PF07645 (EGF_CA)
  
  1,157 - 1,197
  
  Pfam
  PF07645 (EGF_CA)
2. SM00179 (egfca_6)
  
  1,157 - 1,198
  
  SMART
  SM00179 (egfca_6)
IPR002049

Laminin EGF domain
1. PS50027 (EGF_LAM_2)
  
  1,233 - 1,279
  
  PROSITE profiles
  PS50027 (EGF_LAM_2)
  
  1,280 - 1,334
  
  PROSITE profiles
  PS50027 (EGF_LAM_2)
2. PS01248 (EGF_LAM_1)
  
  1,300 - 1,332
  
  PROSITE patterns
  PS01248 (EGF_LAM_1)
3. PF00053 (Laminin_EGF)
  
  1,280 - 1,328
  
  Pfam
  PF00053 (Laminin_EGF)
  
  1,233 - 1,277
  
  Pfam
  PF00053 (Laminin_EGF)
4. SM00180 (lamegf_3)
  
  1,218 - 1,277
  
  SMART
  SM00180 (lamegf_3)
  
  1,280 - 1,328
  
  SMART
  SM00180 (lamegf_3)
IPR015916

Galactose oxidase, beta-propeller
1. G3DSA:2.130.1...
  
  1,551 - 1,646
  
  GENE3D
  G3DSA:2.130.10.80 (G3DSA:2.130.10.80)
IPR002165

Plexin repeat
1. PF01437 (PSI)
  
  1,095 - 1,156
  
  Pfam
  PF01437 (PSI)
IPR006652

Kelch repeat type 1
1. PF01344 (Kelch_1)
  
  1,784 - 1,825
  
  Pfam
  PF01344 (Kelch_1)
IPR013032

EGF-like, conserved site
1. PS00022 (EGF_1)
  
  161 - 172
  
  PROSITE patterns
  PS00022 (EGF_1)
  
  1,509 - 1,520
  
  PROSITE patterns
  PS00022 (EGF_1)
  
  1,300 - 1,311
  
  PROSITE patterns
  PS00022 (EGF_1)
  
  1,218 - 1,229
  
  PROSITE patterns
  PS00022 (EGF_1)
  
  1,473 - 1,484
  
  PROSITE patterns
  PS00022 (EGF_1)
  
  192 - 203
  
  PROSITE patterns
  PS00022 (EGF_1)
2. PS01186 (EGF_2)
  
  1,218 - 1,233
  
  PROSITE patterns
  PS01186 (EGF_2)
  
  1,509 - 1,520
  
  PROSITE patterns
  PS01186 (EGF_2)
  
  1,183 - 1,197
  
  PROSITE patterns
  PS01186 (EGF_2)
  
  1,473 - 1,484
  
  PROSITE patterns
  PS01186 (EGF_2)
  
  192 - 203
  
  PROSITE patterns
  PS01186 (EGF_2)
IPR018097

EGF-like calcium-binding, conserved site
1. PS01187 (EGF_CA)
  
  1,157 - 1,183
  
  PROSITE patterns
  PS01187 (EGF_CA)
IPR000152

EGF-type aspartate/asparagine hydroxylation site
1. PS00010 (ASX_HYDROXYL)
  
  1,174 - 1,185
  
  PROSITE patterns
  PS00010 (ASX_HYDROXYL)

no IPR

Unintegrated signatures

G3DSA:2.10.25.10

180 - 205

GENE3D
G3DSA:2.10.25.10 (G3DSA:2.10.25.10)

1,279 - 1,328

GENE3D
G3DSA:2.10.25.10 (G3DSA:2.10.25.10)

1,233 - 1,277

GENE3D
G3DSA:2.10.25.10 (G3DSA:2.10.25.10)

1,157 - 1,232

GENE3D
G3DSA:2.10.25.10 (G3DSA:2.10.25.10)
PF13415 (Kelch_3)

1,622 - 1,672

Pfam
PF13415 (Kelch_3)
PF13418 (Kelch_4)

228 - 267

Pfam
PF13418 (Kelch_4)

360 - 401

Pfam
PF13418 (Kelch_4)

1,680 - 1,719

Pfam
PF13418 (Kelch_4)

1,552 - 1,594

Pfam
PF13418 (Kelch_4)
PR00011 (EGFLAMININ)

1,502 - 1,520

PRINTS
PR00011 (EGFLAMININ)

1,466 - 1,484

PRINTS
PR00011 (EGFLAMININ)

1,293 - 1,311

PRINTS
PR00011 (EGFLAMININ)
SSF117281 (Kelch motif)

1,778 - 1,903

SUPERFAMILY
SSF117281 (Kelch motif)

210 - 268

SUPERFAMILY
SSF117281 (Kelch motif)

1,551 - 1,773

SUPERFAMILY
SSF117281 (Kelch motif)

358 - 618

SUPERFAMILY
SSF117281 (Kelch motif)
SSF57196 (EGF/Laminin)

1,157 - 1,192

SUPERFAMILY
SSF57196 (EGF/Laminin)

1,280 - 1,328

SUPERFAMILY
SSF57196 (EGF/Laminin)
cd00054 (EGF_CA)

1,157 - 1,192

CDD
cd00054 (EGF_CA)
cd00055 (EGF_Lam)

1,233 - 1,278

CDD
cd00055 (EGF_Lam)

1,279 - 1,329

CDD
cd00055 (EGF_Lam)

Residue annotation

heterodimerization...

43S

heterodimerization interface
43S, 45I, 47T, 75T, 80R, 114N, 138R, 140A
CDD
cd00041 (CUB)

45I

heterodimerization interface
43S, 45I, 47T, 75T, 80R, 114N, 138R, 140A
CDD
cd00041 (CUB)

47T

heterodimerization interface
43S, 45I, 47T, 75T, 80R, 114N, 138R, 140A
CDD
cd00041 (CUB)

75T

heterodimerization interface
43S, 45I, 47T, 75T, 80R, 114N, 138R, 140A
CDD
cd00041 (CUB)

80R

heterodimerization interface
43S, 45I, 47T, 75T, 80R, 114N, 138R, 140A
CDD
cd00041 (CUB)

114N

heterodimerization interface
43S, 45I, 47T, 75T, 80R, 114N, 138R, 140A
CDD
cd00041 (CUB)

138R

heterodimerization interface
43S, 45I, 47T, 75T, 80R, 114N, 138R, 140A
CDD
cd00041 (CUB)

140A

heterodimerization interface
43S, 45I, 47T, 75T, 80R, 114N, 138R, 140A
CDD
cd00041 (CUB)
Ca2+ binding site ...

1,157D

Ca2+ binding site
1,157D, 1,160E, 1,176N
CDD
cd00054 (EGF_CA)

1,160E

Ca2+ binding site
1,157D, 1,160E, 1,176N
CDD
cd00054 (EGF_CA)

1,176N

Ca2+ binding site
1,157D, 1,160E, 1,176N
CDD
cd00054 (EGF_CA)
EGF-like motif cd0...

1,233C

EGF-like motif
1,233C, 1,235C, 1,241C, 1,248C, 1,251C, 1,260C
CDD
cd00055 (EGF_Lam)

1,235C

EGF-like motif
1,233C, 1,235C, 1,241C, 1,248C, 1,251C, 1,260C
CDD
cd00055 (EGF_Lam)

1,241C

EGF-like motif
1,233C, 1,235C, 1,241C, 1,248C, 1,251C, 1,260C
CDD
cd00055 (EGF_Lam)

1,248C

EGF-like motif
1,233C, 1,235C, 1,241C, 1,248C, 1,251C, 1,260C
CDD
cd00055 (EGF_Lam)

1,251C

EGF-like motif
1,233C, 1,235C, 1,241C, 1,248C, 1,251C, 1,260C
CDD
cd00055 (EGF_Lam)

1,260C

EGF-like motif
1,233C, 1,235C, 1,241C, 1,248C, 1,251C, 1,260C
CDD
cd00055 (EGF_Lam)
EGF-like motif cd0...

1,280C

EGF-like motif
1,280C, 1,282C, 1,293C, 1,300C, 1,302C, 1,311C
CDD
cd00055 (EGF_Lam)

1,282C

EGF-like motif
1,280C, 1,282C, 1,293C, 1,300C, 1,302C, 1,311C
CDD
cd00055 (EGF_Lam)

1,293C

EGF-like motif
1,280C, 1,282C, 1,293C, 1,300C, 1,302C, 1,311C
CDD
cd00055 (EGF_Lam)

1,300C

EGF-like motif
1,280C, 1,282C, 1,293C, 1,300C, 1,302C, 1,311C
CDD
cd00055 (EGF_Lam)

1,302C

EGF-like motif
1,280C, 1,282C, 1,293C, 1,300C, 1,302C, 1,311C
CDD
cd00055 (EGF_Lam)

1,311C

EGF-like motif
1,280C, 1,282C, 1,293C, 1,300C, 1,302C, 1,311C
CDD
cd00055 (EGF_Lam)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding

Cellular Component

GO:0016020 membrane

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO02001

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component