KWMTBOMO01922

Protein

Length

1,068 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
30 - 252
Adenylate cyclase, N-terminal (IPR032628)
Domain
227 - 445
Nucleotide cyclase (IPR029787)
Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054)
782 - 1,017
Nucleotide cyclase (IPR029787)
Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054)

1 100 200 300 400 500 600 700 800 900 1000 1068

Detailed signature matches

IPR032628

Adenylate cyclase, N-terminal
1. PF16214 (AC_N)
  
  30 - 252
  
  Pfam
  PF16214 (AC_N)
IPR029787

Nucleotide cyclase
1. SSF55073 (Nucleotid...)
  
  816 - 1,012
  
  SUPERFAMILY
  SSF55073 (Nucleotide cyclase)
  
  260 - 424
  
  SUPERFAMILY
  SSF55073 (Nucleotide cyclase)
IPR001054

Adenylyl cyclase class-3/4/guanylyl cyclase
1. PS50125 (GUANYLATE_...)
  
  271 - 398
  
  PROSITE profiles
  PS50125 (GUANYLATE_CYCLASE_2)
  
  822 - 968
  
  PROSITE profiles
  PS50125 (GUANYLATE_CYCLASE_2)
2. SM00044 (cyc_6)
  
  782 - 996
  
  SMART
  SM00044 (cyc_6)
  
  227 - 424
  
  SMART
  SM00044 (cyc_6)
3. G3DSA:3.30.70...
  
  258 - 445
  
  GENE3D
  G3DSA:3.30.70.1230 (G3DSA:3.30.70.1230)
  
  810 - 1,017
  
  GENE3D
  G3DSA:3.30.70.1230 (G3DSA:3.30.70.1230)
4. PF00211 (Guanylate_cyc)
  
  263 - 444
  
  Pfam
  PF00211 (Guanylate_cyc)
  
  814 - 1,013
  
  Pfam
  PF00211 (Guanylate_cyc)
IPR018297

Adenylyl cyclase class-4/guanylyl cyclase, conserved site
1. PS00452 (GUANYLATE_...)
  
  945 - 968
  
  PROSITE patterns
  PS00452 (GUANYLATE_CYCLASE_1)

no IPR

Unintegrated signatures

Coil

296 - 316

COILS
Coil (Coil)
cd07302 (CHD)

269 - 444

CDD
cd07302 (CHD)

820 - 1,012

CDD
cd07302 (CHD)
mobidb-lite (disord...)

1,013 - 1,068

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

nucleotidyl bindin...

274Y

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

276D

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

277I

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

278V

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

279G

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

280F

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

281T

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

316K

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

318L

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

319G

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

320D

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

323Y

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

385D

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

386V

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

387Y

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

391V

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

392E

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

395N

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

396K

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)

435R

nucleotidyl binding site
274Y, 276D, 277I, 278V, 279G, 280F, 281T, 316K, 318L, 319G, 320D, 323Y, 385D, 386V, 387Y, 391V, 392E, 395N, 396K, 435R
CDD
cd07302 (CHD)
metal binding site...

276D

metal binding site
276D, 320D
CDD
cd07302 (CHD)

320D

metal binding site
276D, 320D
CDD
cd07302 (CHD)
dimer interface cd...

281T

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

293V

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

296L

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

297N

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

300F

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

304D

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

316K

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

317I

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

373L

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

376V

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

386V

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

387Y

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

388S

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

389R

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

392E

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)

435R

dimer interface
281T, 293V, 296L, 297N, 300F, 304D, 316K, 317I, 373L, 376V, 386V, 387Y, 388S, 389R, 392E, 435R
CDD
cd07302 (CHD)
nucleotidyl bindin...

825F

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

827S

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

828M

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

829P

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

830N

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

831F

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

832T

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

875K

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

877I

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

878S

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

879S

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

882M

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

955D

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

956I

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

957W

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

961V

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

962N

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

965S

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

966R

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)

1,002K

nucleotidyl binding site
825F, 827S, 828M, 829P, 830N, 831F, 832T, 875K, 877I, 878S, 879S, 882M, 955D, 956I, 957W, 961V, 962N, 965S, 966R, 1,002K
CDD
cd07302 (CHD)
metal binding site...

827S

metal binding site
827S, 879S
CDD
cd07302 (CHD)

879S

metal binding site
827S, 879S
CDD
cd07302 (CHD)
dimer interface cd...

832T

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

848L

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

851L

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

852N

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

855I

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

859D

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

875K

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

876T

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

943T

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

946V

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

956I

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

957W

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

958G

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

959N

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

962N

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

1,002K

dimer interface
832T, 848L, 851L, 852N, 855I, 859D, 875K, 876T, 943T, 946V, 956I, 957W, 958G, 959N, 962N, 1,002K
CDD
cd07302 (CHD)

GO term prediction

Biological Process

GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction

Molecular Function

GO:0016849 phosphorus-oxygen lyase activity

Cellular Component