KWMTBOMO01798

Protein

Length

1,989 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
38 - 677
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Myosin head, motor domain (IPR001609)
843 - 1,069
MyTH4 domain (IPR000857)
1,163 - 1,262
FERM/acyl-CoA-binding protein, 3-helical bundle (IPR014352)
FERM central domain (IPR019748)
1,383 - 1,456
SH3 domain (IPR001452)
1,525 - 1,673
MyTH4 domain (IPR000857)
1,772 - 1,893
FERM/acyl-CoA-binding protein, 3-helical bundle (IPR014352)
FERM central domain (IPR019748)
Domain
1,068 - 1,171
Ubiquitin-related domain (IPR029071)
1,671 - 1,780
Ubiquitin-related domain (IPR029071)
FERM, N-terminal (IPR018979)
1,888 - 1,978
PH domain-like (IPR011993)
Domain
1,070 - 1,291
Band 4.1 domain (IPR019749)
1,402 - 1,445
Variant SH3 domain (IPR011511)
1,675 - 1,893
Band 4.1 domain (IPR019749)
Domain
1,074 - 1,385
FERM domain (IPR000299)
1,679 - 1,983
FERM domain (IPR000299)

1 200 400 600 800 1000 1200 1400 1600 1800 1989

Detailed signature matches

IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  38 - 665
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
2. G3DSA:3.40.50...
  
  148 - 188
  
  GENE3D
  G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
  
  571 - 677
  
  GENE3D
  G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
IPR001609

Myosin head, motor domain
1. PS51456 (MYOSIN_MOTOR)
  
  64 - 614
  
  PROSITE profiles
  PS51456 (MYOSIN_MOTOR)
2. PR00193 (MYOSINHEAVY)
  
  150 - 175
  
  PRINTS
  PR00193 (MYOSINHEAVY)
  
  193 - 220
  
  PRINTS
  PR00193 (MYOSINHEAVY)
  
  94 - 113
  
  PRINTS
  PR00193 (MYOSINHEAVY)
3. SM00242 (MYSc_2a)
  
  58 - 615
  
  SMART
  SM00242 (MYSc_2a)
4. PF00063 (Myosin_head)
  
  228 - 602
  
  Pfam
  PF00063 (Myosin_head)
  
  66 - 226
  
  Pfam
  PF00063 (Myosin_head)
IPR000857

MyTH4 domain
1. PS51016 (MYTH4)
  
  1,525 - 1,673
  
  PROSITE profiles
  PS51016 (MYTH4)
  
  843 - 1,069
  
  PROSITE profiles
  PS51016 (MYTH4)
2. SM00139 (MyTH4_1)
  
  1,525 - 1,673
  
  SMART
  SM00139 (MyTH4_1)
  
  843 - 1,069
  
  SMART
  SM00139 (MyTH4_1)
3. PF00784 (MyTH4)
  
  1,573 - 1,672
  
  Pfam
  PF00784 (MyTH4)
  
  970 - 1,067
  
  Pfam
  PF00784 (MyTH4)
IPR029071

Ubiquitin-related domain
1. SSF54236 (Ubiquitin...)
  
  1,671 - 1,780
  
  SUPERFAMILY
  SSF54236 (Ubiquitin-like)
  
  1,068 - 1,171
  
  SUPERFAMILY
  SSF54236 (Ubiquitin-like)
IPR019749

Band 4.1 domain
1. SM00295 (B41_5)
  
  1,675 - 1,893
  
  SMART
  SM00295 (B41_5)
  
  1,070 - 1,291
  
  SMART
  SM00295 (B41_5)
IPR000299

FERM domain
1. PS50057 (FERM_3)
  
  1,074 - 1,385
  
  PROSITE profiles
  PS50057 (FERM_3)
  
  1,679 - 1,983
  
  PROSITE profiles
  PS50057 (FERM_3)
IPR014352

FERM/acyl-CoA-binding protein, 3-helical bundle
1. G3DSA:1.20.80.10
  
  1,167 - 1,262
  
  GENE3D
  G3DSA:1.20.80.10 (G3DSA:1.20.80.10)
  
  1,791 - 1,886
  
  GENE3D
  G3DSA:1.20.80.10 (G3DSA:1.20.80.10)
IPR019748

FERM central domain
1. SSF47031 (Second do...)
  
  1,772 - 1,888
  
  SUPERFAMILY
  SSF47031 (Second domain of FERM)
  
  1,163 - 1,260
  
  SUPERFAMILY
  SSF47031 (Second domain of FERM)
2. PF00373 (FERM_M)
  
  1,791 - 1,893
  
  Pfam
  PF00373 (FERM_M)
IPR001452

SH3 domain
1. PS50002 (SH3)
  
  1,383 - 1,450
  
  PROSITE profiles
  PS50002 (SH3)
2. SSF50044 (SH3-domain)
  
  1,398 - 1,456
  
  SUPERFAMILY
  SSF50044 (SH3-domain)
3. SM00326 (SH3_2)
  
  1,386 - 1,449
  
  SMART
  SM00326 (SH3_2)
IPR011511

Variant SH3 domain
1. PF07653 (SH3_2)
  
  1,402 - 1,445
  
  Pfam
  PF07653 (SH3_2)
IPR018979

FERM, N-terminal
1. PF09379 (FERM_N)
  
  1,683 - 1,751
  
  Pfam
  PF09379 (FERM_N)
IPR011993

PH domain-like
1. G3DSA:2.30.29.30
  
  1,888 - 1,978
  
  GENE3D
  G3DSA:2.30.29.30 (G3DSA:2.30.29.30)
2. SSF50729 (PH domain...)
  
  1,889 - 1,977
  
  SUPERFAMILY
  SSF50729 (PH domain-like)
IPR000048

IQ motif, EF-hand binding site
1. PF00612 (IQ)
  
  693 - 706
  
  Pfam
  PF00612 (IQ)
2. PS50096 (IQ)
  
  640 - 669
  
  PROSITE profiles
  PS50096 (IQ)
  
  686 - 715
  
  PROSITE profiles
  PS50096 (IQ)
  
  618 - 646
  
  PROSITE profiles
  PS50096 (IQ)
3. SM00015 (iq_5)
  
  685 - 707
  
  SMART
  SM00015 (iq_5)
  
  639 - 661
  
  SMART
  SM00015 (iq_5)
  
  616 - 638
  
  SMART
  SM00015 (iq_5)

no IPR

Unintegrated signatures

G3DSA:2.30.30.40

1,404 - 1,456

GENE3D
G3DSA:2.30.30.40 (G3DSA:2.30.30.40)
G3DSA:3.10.20.90

1,682 - 1,757

GENE3D
G3DSA:3.10.20.90 (G3DSA:3.10.20.90)
cd13198 (FERM_C1_My...)

1,285 - 1,384

CDD
cd13198 (FERM_C1_MyoVII)
cd13199 (FERM_C2_My...)

1,889 - 1,976

CDD
cd13199 (FERM_C2_MyoVII)
cd14473 (FERM_B-lobe)

1,179 - 1,256

CDD
cd14473 (FERM_B-lobe)

1,791 - 1,885

CDD
cd14473 (FERM_B-lobe)

Residue annotation

CEN1 peptide bindi...

1,285M

CEN1 peptide binding site
1,285M, 1,286L, 1,290F, 1,292E, 1,307I, 1,322E
CDD
cd13198 (FERM_C1_MyoVII)

1,286L

CEN1 peptide binding site
1,285M, 1,286L, 1,290F, 1,292E, 1,307I, 1,322E
CDD
cd13198 (FERM_C1_MyoVII)

1,290F

CEN1 peptide binding site
1,285M, 1,286L, 1,290F, 1,292E, 1,307I, 1,322E
CDD
cd13198 (FERM_C1_MyoVII)

1,292E

CEN1 peptide binding site
1,285M, 1,286L, 1,290F, 1,292E, 1,307I, 1,322E
CDD
cd13198 (FERM_C1_MyoVII)

1,307I

CEN1 peptide binding site
1,285M, 1,286L, 1,290F, 1,292E, 1,307I, 1,322E
CDD
cd13198 (FERM_C1_MyoVII)

1,322E

CEN1 peptide binding site
1,285M, 1,286L, 1,290F, 1,292E, 1,307I, 1,322E
CDD
cd13198 (FERM_C1_MyoVII)
putative phosphoin...

1,295K

putative phosphoinositide binding site
1,295K, 1,317I, 1,319D, 1,326L
CDD
cd13198 (FERM_C1_MyoVII)

1,317I

putative phosphoinositide binding site
1,295K, 1,317I, 1,319D, 1,326L
CDD
cd13198 (FERM_C1_MyoVII)

1,319D

putative phosphoinositide binding site
1,295K, 1,317I, 1,319D, 1,326L
CDD
cd13198 (FERM_C1_MyoVII)

1,326L

putative phosphoinositide binding site
1,295K, 1,317I, 1,319D, 1,326L
CDD
cd13198 (FERM_C1_MyoVII)
putative actin bin...

1,371S

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,372S

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,373L

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,374I

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,375I

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,376Y

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,377I

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,378I

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,379D

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,380G

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,381L

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)

1,382K

putative actin binding site 2
1,371S, 1,372S, 1,373L, 1,374I, 1,375I, 1,376Y, 1,377I, 1,378I, 1,379D, 1,380G, 1,381L, 1,382K
CDD
cd13198 (FERM_C1_MyoVII)
putative phosphoin...

1,897Q

putative phosphoinositide binding site
1,897Q, 1,918L, 1,920H, 1,926V
CDD
cd13199 (FERM_C2_MyoVII)

1,918L

putative phosphoinositide binding site
1,897Q, 1,918L, 1,920H, 1,926V
CDD
cd13199 (FERM_C2_MyoVII)

1,920H

putative phosphoinositide binding site
1,897Q, 1,918L, 1,920H, 1,926V
CDD
cd13199 (FERM_C2_MyoVII)

1,926V

putative phosphoinositide binding site
1,897Q, 1,918L, 1,920H, 1,926V
CDD
cd13199 (FERM_C2_MyoVII)
putative peptide b...

1,930H

putative peptide binding site
1,930H, 1,934Q, 1,935L, 1,936S, 1,937N, 1,972I, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,934Q

putative peptide binding site
1,930H, 1,934Q, 1,935L, 1,936S, 1,937N, 1,972I, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,935L

putative peptide binding site
1,930H, 1,934Q, 1,935L, 1,936S, 1,937N, 1,972I, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,936S

putative peptide binding site
1,930H, 1,934Q, 1,935L, 1,936S, 1,937N, 1,972I, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,937N

putative peptide binding site
1,930H, 1,934Q, 1,935L, 1,936S, 1,937N, 1,972I, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,972I

putative peptide binding site
1,930H, 1,934Q, 1,935L, 1,936S, 1,937N, 1,972I, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,976I

putative peptide binding site
1,930H, 1,934Q, 1,935L, 1,936S, 1,937N, 1,972I, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)
putative actin bin...

1,972I

putative actin binding site 2
1,972I, 1,973S, 1,974S, 1,975Y, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,973S

putative actin binding site 2
1,972I, 1,973S, 1,974S, 1,975Y, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,974S

putative actin binding site 2
1,972I, 1,973S, 1,974S, 1,975Y, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,975Y

putative actin binding site 2
1,972I, 1,973S, 1,974S, 1,975Y, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

1,976I

putative actin binding site 2
1,972I, 1,973S, 1,974S, 1,975Y, 1,976I
CDD
cd13199 (FERM_C2_MyoVII)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003774 motor activity
GO:0005515 protein binding
GO:0005524 ATP binding

Cellular Component

GO:0005856 cytoskeleton
GO:0016459 myosin complex

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Entry type

Status

Per-residue features