KWMTBOMO01604

Protein

Length

528 amino acids

Protein family membership

Alkaline phosphatase (IPR001952)

Domains and repeats

Domain
48 - 521
Alkaline-phosphatase-like, core domain (IPR017850)
Domain
48 - 522
Alkaline phosphatase-like, alpha/beta/alpha (IPR017849)

1 50 100 150 200 250 300 350 400 450 500 528

Detailed signature matches

IPR001952

Alkaline phosphatase
1. SM00098 (alk_phosph_2)
  
  75 - 514
  
  SMART
  SM00098 (alk_phosph_2)
2. PR00113 (ALKPHPHTASE)
  
  179 - 199
  
  PRINTS
  PR00113 (ALKPHPHTASE)
  
  241 - 251
  
  PRINTS
  PR00113 (ALKPHPHTASE)
  
  331 - 360
  
  PRINTS
  PR00113 (ALKPHPHTASE)
  
  74 - 94
  
  PRINTS
  PR00113 (ALKPHPHTASE)
  
  130 - 145
  
  PRINTS
  PR00113 (ALKPHPHTASE)
3. cd00016 (alkPPc)
  
  74 - 513
  
  CDD
  cd00016 (alkPPc)
4. PF00245 (Alk_phosph...)
  
  74 - 513
  
  Pfam
  PF00245 (Alk_phosphatase)
IPR017850

Alkaline-phosphatase-like, core domain
1. SSF53649 (Alkaline ...)
  
  48 - 521
  
  SUPERFAMILY
  SSF53649 (Alkaline phosphatase-like)
IPR017849

Alkaline phosphatase-like, alpha/beta/alpha
1. G3DSA:3.40.72...
  
  48 - 522
  
  GENE3D
  G3DSA:3.40.720.10 (G3DSA:3.40.720.10)

no IPR

Unintegrated signatures

PS51257 (PROKAR_LIP...)

1 - 16

PROSITE profiles
PS51257 (PROKAR_LIPOPROTEIN)
mobidb-lite (disord...)

31 - 52

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

active site cd00016

83D

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

132D

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

133S

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

196H

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

198S

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

209R

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

355E

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

360D

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

361H

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

364H

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

401D

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

402H

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)

477H

active site
83D, 132D, 133S, 196H, 198S, 209R, 355E, 360D, 361H, 364H, 401D, 402H, 477H
CDD
cd00016 (alkPPc)
dimer interface cd...

87V

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

88A

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

91T

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

94R

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

95T

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

113E

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

116P

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

118V

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

119G

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

120L

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

122K

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

124Y

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

126L

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

130V

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

143G

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

144A

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

145K

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

155G

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

172L

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

405V

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

407S

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

408I

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

409S

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

410G

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

432Y

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

433M

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

438G

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

439N

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

476T

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

478G

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

479G

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

480D

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

481D

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

483A

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

496G

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

497L

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

498Y

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

499E

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

501S

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

502H

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

505H

dimer interface
87V, 88A, 91T, 94R, 95T, 113E, 116P, 118V, 119G, 120L, 122K, 124Y, 126L, 130V, 143G, 144A, 145K, 155G, 172L, 405V, 407S, 408I, 409S, 410G, 432Y, 433M, 438G, 439N, 476T, 478G, 479G, 480D, 481D, 483A, 496G, 497L, 498Y, 499E, 501S, 502H, 505H
CDD
cd00016 (alkPPc)

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0016791 phosphatase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features