KWMTBOMO01476

Protein

Length

324 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
5 - 118
NAD(P)-binding domain (IPR016040)
109 - 295
NAD(P)-binding domain (IPR016040)
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (IPR006140)
Domain
14 - 320
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (IPR006139)

1 50 100 150 200 250 324

Detailed signature matches

IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  109 - 292
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
2. G3DSA:3.40.50...
  
  119 - 295
  
  GENE3D
  G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
  
  5 - 118
  
  GENE3D
  G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
IPR006139

D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
1. PF00389 (2-Hacid_dh)
  
  14 - 320
  
  Pfam
  PF00389 (2-Hacid_dh)
IPR006140

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
1. PF02826 (2-Hacid_dh_C)
  
  115 - 292
  
  Pfam
  PF02826 (2-Hacid_dh_C)
IPR029753

D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site
1. PS00671 (D_2_HYDROX...)
  
  231 - 247
  
  PROSITE patterns
  PS00671 (D_2_HYDROXYACID_DH_3)

no IPR

Unintegrated signatures

SSF52283 (Formate/g...)

6 - 141

SUPERFAMILY
SSF52283 (Formate/glycerate dehydrogenase catalytic domain-like)
cd05301 (GDH)

4 - 316

CDD
cd05301 (GDH)

Residue annotation

dimerization inter...

11G

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

12S

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

14P

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

57N

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

58T

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

59K

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

80M

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

108N

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

109A

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

112D

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

113I

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

115V

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

116G

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

119I

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

123R

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

125F

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

133E

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

135N

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

137W

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

139F

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

140G

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

141V

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

142Q

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

143W

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

144I

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

146G

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

147Q

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

148D

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

149I

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

150A

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

168R

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

169R

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

172G

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

173F

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

271E

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

272P

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

280L

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

286Y

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

287L

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

288I

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

289P

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

290H

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

291L

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

292G

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

294A

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

295T

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

296I

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

297E

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)

299R

dimerization interface
11G, 12S, 14P, 57N, 58T, 59K, 80M, 108N, 109A, 112D, 113I, 115V, 116G, 119I, 123R, 125F, 133E, 135N, 137W, 139F, 140G, 141V, 142Q, 143W, 144I, 146G, 147Q, 148D, 149I, 150A, 168R, 169R, 172G, 173F, 271E, 272P, 280L, 286Y, 287L, 288I, 289P, 290H, 291L, 292G, 294A, 295T, 296I, 297E, 299R
CDD
cd05301 (GDH)
ligand binding sit...

58T

ligand binding site
58T, 81A, 82S, 83G, 106L, 242R, 290H, 293S
CDD
cd05301 (GDH)

81A

ligand binding site
58T, 81A, 82S, 83G, 106L, 242R, 290H, 293S
CDD
cd05301 (GDH)

82S

ligand binding site
58T, 81A, 82S, 83G, 106L, 242R, 290H, 293S
CDD
cd05301 (GDH)

83G

ligand binding site
58T, 81A, 82S, 83G, 106L, 242R, 290H, 293S
CDD
cd05301 (GDH)

106L

ligand binding site
58T, 81A, 82S, 83G, 106L, 242R, 290H, 293S
CDD
cd05301 (GDH)

242R

ligand binding site
58T, 81A, 82S, 83G, 106L, 242R, 290H, 293S
CDD
cd05301 (GDH)

290H

ligand binding site
58T, 81A, 82S, 83G, 106L, 242R, 290H, 293S
CDD
cd05301 (GDH)

293S

ligand binding site
58T, 81A, 82S, 83G, 106L, 242R, 290H, 293S
CDD
cd05301 (GDH)
NADP binding site ...

82S

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

83G

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

110V

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

181C

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

182G

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

183R

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

186K

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

212V

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

213C

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

214P

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

218E

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

219T

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

240I

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

241A

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

242R

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

266D

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

267V

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

290H

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

292G

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)

293S

NADP binding site
82S, 83G, 110V, 181C, 182G, 183R, 186K, 212V, 213C, 214P, 218E, 219T, 240I, 241A, 242R, 266D, 267V, 290H, 292G, 293S
CDD
cd05301 (GDH)
catalytic site cd0...

242R

catalytic site
242R, 271E, 290H
CDD
cd05301 (GDH)

271E

catalytic site
242R, 271E, 290H
CDD
cd05301 (GDH)

290H

catalytic site
242R, 271E, 290H
CDD
cd05301 (GDH)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

Cellular Component