KWMTBOMO01435

Protein

Length

2,424 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
1 - 272
Armadillo-type fold (IPR016024)
Armadillo-like helical (IPR011989)
328 - 506
Armadillo-type fold (IPR016024)
Armadillo-like helical (IPR011989)
571 - 1,191
Armadillo-type fold (IPR016024)
Armadillo-like helical (IPR011989)
1,232 - 1,448
Armadillo-type fold (IPR016024)
Armadillo-like helical (IPR011989)
1,434 - 1,569
Armadillo-like helical (IPR011989)
1,830 - 1,996
Armadillo-like helical (IPR011989)
Domain
812 - 980
Domain of unknown function DUF3385, target of rapamycin protein (IPR024585)
1,403 - 1,433
Tetratricopeptide-like helical domain (IPR011990)
1,711 - 1,737
Tetratricopeptide-like helical domain (IPR011990)
1,906 - 2,003
FKBP12-rapamycin binding domain (IPR009076)
2,392 - 2,424
FATC domain (IPR003152)
Domain
1,332 - 1,873
PIK-related kinase (IPR014009)
PIK-related kinase, FAT (IPR003151)
1,985 - 2,424
Protein kinase-like domain (IPR011009)
Phosphatidylinositol 3-/4-kinase, catalytic domain (IPR000403)

1 500 1000 1500 2000 2424

Detailed signature matches

IPR016024

Armadillo-type fold
1. SSF48371 (ARM repeat)
  
  616 - 1,191
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  374 - 500
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  1 - 206
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  1,232 - 1,448
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
IPR011989

Armadillo-like helical
1. G3DSA:1.25.10.10
  
  1,265 - 1,372
  
  GENE3D
  G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
  
  1,434 - 1,569
  
  GENE3D
  G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
  
  1,830 - 1,996
  
  GENE3D
  G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
  
  696 - 1,167
  
  GENE3D
  G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
  
  328 - 506
  
  GENE3D
  G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
  
  571 - 643
  
  GENE3D
  G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
  
  6 - 272
  
  GENE3D
  G3DSA:1.25.10.10 (G3DSA:1.25.10.10)
IPR024585

Domain of unknown function DUF3385, target of rapamycin protein
1. PF11865 (DUF3385)
  
  812 - 980
  
  Pfam
  PF11865 (DUF3385)
2. SM01346 (DUF3385_3)
  
  812 - 980
  
  SMART
  SM01346 (DUF3385_3)
IPR014009

PIK-related kinase
1. PS51189 (FAT)
  
  1,332 - 1,873
  
  PROSITE profiles
  PS51189 (FAT)
IPR011990

Tetratricopeptide-like helical domain
1. G3DSA:1.25.40.10
  
  1,711 - 1,737
  
  GENE3D
  G3DSA:1.25.40.10 (G3DSA:1.25.40.10)
  
  1,403 - 1,433
  
  GENE3D
  G3DSA:1.25.40.10 (G3DSA:1.25.40.10)
IPR003151

PIK-related kinase, FAT
1. PF02259 (FAT)
  
  1,467 - 1,799
  
  Pfam
  PF02259 (FAT)
IPR009076

FKBP12-rapamycin binding domain
1. PF08771 (FRB_dom)
  
  1,906 - 2,003
  
  Pfam
  PF08771 (FRB_dom)
2. SSF47212 (FKBP12-ra...)
  
  1,910 - 2,003
  
  SUPERFAMILY
  SSF47212 (FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP))
IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  1,985 - 2,150
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  2,185 - 2,327
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000403

Phosphatidylinositol 3-/4-kinase, catalytic domain
1. G3DSA:1.10.10...
  
  2,376 - 2,416
  
  GENE3D
  G3DSA:1.10.1070.11 (G3DSA:1.10.1070.11)
  
  2,192 - 2,322
  
  GENE3D
  G3DSA:1.10.1070.11 (G3DSA:1.10.1070.11)
  
  2,123 - 2,137
  
  GENE3D
  G3DSA:1.10.1070.11 (G3DSA:1.10.1070.11)
2. SM00146 (pi3k_hr1_6)
  
  2,074 - 2,407
  
  SMART
  SM00146 (pi3k_hr1_6)
3. PF00454 (PI3_PI4_ki...)
  
  2,073 - 2,321
  
  Pfam
  PF00454 (PI3_PI4_kinase)
4. PS50290 (PI3_4_KINA...)
  
  2,073 - 2,424
  
  PROSITE profiles
  PS50290 (PI3_4_KINASE_3)
IPR003152

FATC domain
1. SM01343 (FATC_2)
  
  2,392 - 2,424
  
  SMART
  SM01343 (FATC_2)
2. PF02260 (FATC)
  
  2,395 - 2,424
  
  Pfam
  PF02260 (FATC)
3. PS51190 (FATC)
  
  2,392 - 2,424
  
  PROSITE profiles
  PS51190 (FATC)
IPR018936

Phosphatidylinositol 3/4-kinase, conserved site
1. PS00916 (PI3_4_KINA...)
  
  2,214 - 2,234
  
  PROSITE patterns
  PS00916 (PI3_4_KINASE_2)
2. PS00915 (PI3_4_KINA...)
  
  2,077 - 2,091
  
  PROSITE patterns
  PS00915 (PI3_4_KINASE_1)

no IPR

Unintegrated signatures

Coil

1,369 - 1,389

COILS
Coil (Coil)
G3DSA:3.30.10...

1,997 - 2,122

GENE3D
G3DSA:3.30.1010.10 (G3DSA:3.30.1010.10)
SM01345 (Rapamycin_...)

1,906 - 2,005

SMART
SM01345 (Rapamycin_bind_3)
cd05169 (PIKKc_TOR)

2,044 - 2,322

CDD
cd05169 (PIKKc_TOR)
mobidb-lite (disord...)

2,331 - 2,366

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

2,054I

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,056S

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,057K

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,058Q

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,060P

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,076L

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,078K

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,081E

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,116Y

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,128I

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,129G

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,130W

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,131V

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,136T

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,234N

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,236M

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,247I

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)

2,248D

ATP binding site
2,054I, 2,056S, 2,057K, 2,058Q, 2,060P, 2,076L, 2,078K, 2,081E, 2,116Y, 2,128I, 2,129G, 2,130W, 2,131V, 2,136T, 2,234N, 2,236M, 2,247I, 2,248D
CDD
cd05169 (PIKKc_TOR)
mLST8 interface cd...

2,163A

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,164S

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,165D

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,168K

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,169L

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,170M

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,171L

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,173Q

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,175V

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,176E

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)

2,179E

mLST8 interface
2,163A, 2,164S, 2,165D, 2,168K, 2,169L, 2,170M, 2,171L, 2,173Q, 2,175V, 2,176E, 2,179E
CDD
cd05169 (PIKKc_TOR)
catalytic loop cd0...

2,226G

catalytic loop
2,226G, 2,227L, 2,228G, 2,229D, 2,230R, 2,231H, 2,232P, 2,233S, 2,234N
CDD
cd05169 (PIKKc_TOR)

2,227L

catalytic loop
2,226G, 2,227L, 2,228G, 2,229D, 2,230R, 2,231H, 2,232P, 2,233S, 2,234N
CDD
cd05169 (PIKKc_TOR)

2,228G

catalytic loop
2,226G, 2,227L, 2,228G, 2,229D, 2,230R, 2,231H, 2,232P, 2,233S, 2,234N
CDD
cd05169 (PIKKc_TOR)

2,229D

catalytic loop
2,226G, 2,227L, 2,228G, 2,229D, 2,230R, 2,231H, 2,232P, 2,233S, 2,234N
CDD
cd05169 (PIKKc_TOR)

2,230R

catalytic loop
2,226G, 2,227L, 2,228G, 2,229D, 2,230R, 2,231H, 2,232P, 2,233S, 2,234N
CDD
cd05169 (PIKKc_TOR)

2,231H

catalytic loop
2,226G, 2,227L, 2,228G, 2,229D, 2,230R, 2,231H, 2,232P, 2,233S, 2,234N
CDD
cd05169 (PIKKc_TOR)

2,232P

catalytic loop
2,226G, 2,227L, 2,228G, 2,229D, 2,230R, 2,231H, 2,232P, 2,233S, 2,234N
CDD
cd05169 (PIKKc_TOR)

2,233S

catalytic loop
2,226G, 2,227L, 2,228G, 2,229D, 2,230R, 2,231H, 2,232P, 2,233S, 2,234N
CDD
cd05169 (PIKKc_TOR)

2,234N

catalytic loop
2,226G, 2,227L, 2,228G, 2,229D, 2,230R, 2,231H, 2,232P, 2,233S, 2,234N
CDD
cd05169 (PIKKc_TOR)
activation loop (A...

2,248D

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,249F

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,250G

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,251D

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,252C

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,253F

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,254E

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,255V

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,256A

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,257V

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,258T

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,259R

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,260D

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,261K

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,262F

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,263P

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,264E

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,265K

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,266I

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,267P

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,268F

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,269R

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,270L

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

2,271T

activation loop (A-loop)
2,248D, 2,249F, 2,250G, 2,251D, 2,252C, 2,253F, 2,254E, 2,255V, 2,256A, 2,257V, 2,258T, 2,259R, 2,260D, 2,261K, 2,262F, 2,263P, 2,264E, 2,265K, 2,266I, 2,267P, 2,268F, 2,269R, 2,270L, 2,271T
CDD
cd05169 (PIKKc_TOR)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005488 binding
GO:0005515 protein binding
GO:0016301 kinase activity
GO:0044877 macromolecular complex binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

KWMTBOMO01435

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component