KWMTBOMO01287

Protein

Length

483 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
1 - 452
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 483

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  2 - 410
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  1 - 452
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  66 - 447
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  1 - 24
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  65 - 449
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

250 - 450

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

65 - 228

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

1 - 24

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
mobidb-lite (disord...)

462 - 483

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

77L

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

80Y

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

81F

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

84Y

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

88S

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

89V

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

91S

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

92G

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

140G

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

141G

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

144F

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

145P

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

148H

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

149A

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

152A

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

164V

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

165S

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

168L

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

174T

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

271N

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

274L

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

275Y

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

278M

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

279T

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

282P

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

296T

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

300S

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

304Y

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

307R

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

311S

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

368S

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

371S

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

372N

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

375A

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

379N

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

380L

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

383H

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

394L

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

395Y

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

398A

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

399N

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

402G

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

403N

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

406G

putative substrate translocation pore
77L, 80Y, 81F, 84Y, 88S, 89V, 91S, 92G, 140G, 141G, 144F, 145P, 148H, 149A, 152A, 164V, 165S, 168L, 174T, 271N, 274L, 275Y, 278M, 279T, 282P, 296T, 300S, 304Y, 307R, 311S, 368S, 371S, 372N, 375A, 379N, 380L, 383H, 394L, 395Y, 398A, 399N, 402G, 403N, 406G
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

KWMTBOMO01287

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component