Protein

KWMTBOMO00988

Length
1,774 amino acids

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
  4. Domain
1 200 400 600 800 1000 1200 1400 1600 1774

Detailed signature matches

  1. Family IPR006077
    Vinculin/alpha-catenin
    1. SSF47220 (alpha-cat...)
  2. Domain IPR032425
    Talin, N-terminal F0 domain
    1. PF16511 (FERM_f0)
  3. Domain IPR019749
    Band 4.1 domain
    1. SM00295 (B41_5)
  4. Domain IPR000299
    FERM domain
    1. PS50057 (FERM_3)
  5. Domain IPR018979
    FERM, N-terminal
    1. PF09379 (FERM_N)
  6. Domain IPR014352
    FERM/acyl-CoA-binding protein, 3-helical bundle
    1. G3DSA:1.20.80.10
  7. Domain IPR019748
    FERM central domain
    1. SSF47031 (Second do...)
    2. PF00373 (FERM_M)
  8. Domain IPR011993
    PH domain-like
    1. G3DSA:2.30.29.30
    2. SSF50729 (PH domain...)
  9. Domain IPR002404
    IRS-type PTB domain
    1. PF02174 (IRS)
  10. Domain IPR015224
    Talin, central
    1. G3DSA:1.20.14...
    2. PF09141 (Talin_middle)
    3. SSF109880 (A middle...)
  11. Domain IPR002558
    I/LWEQ domain
    1. SSF109885 (I/LWEQ d...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.14...
  3. G3DSA:1.20.14...
  4. SM01244 (IRS_2)
  5. cd10569 (FERM_C_Talin)
  6. cd14473 (FERM_B-lobe)

Residue annotation

  1. putative phosphoin...
  2. homodimer interfac...
  3. peptide binding si...
  4. putative actin bin...

GO term prediction

Biological Process

GO:0007016 cytoskeletal anchoring at plasma membrane
GO:0007155 cell adhesion

Molecular Function

GO:0003779 actin binding
GO:0005158 insulin receptor binding
GO:0005200 structural constituent of cytoskeleton
GO:0051015 actin filament binding

Cellular Component

GO:0001726 ruffle
GO:0005856 cytoskeleton
GO:0005925 focal adhesion