KWMTBOMO00954

Protein

Length

479 amino acids

Protein family membership

Adenosylhomocysteinase (IPR000043)

Domains and repeats

Domain
238 - 399
S-adenosyl-L-homocysteine hydrolase, NAD binding domain (IPR015878)
Domain
238 - 397
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 300 350 400 450 479

Detailed signature matches

IPR000043

Adenosylhomocysteinase
1. TIGR00936
  
  53 - 471
  
  TIGRFAMs
  TIGR00936 (TIGR00936)
2. PF05221 (AdoHcyase)
  
  53 - 188
  
  Pfam
  PF05221 (AdoHcyase)
  
  189 - 478
  
  Pfam
  PF05221 (AdoHcyase)
3. SM00996 (AdoHcyase_2)
  
  52 - 478
  
  SMART
  SM00996 (AdoHcyase_2)
4. PIRSF001109 (SAHH)
  
  40 - 479
  
  PIRSF
  PIRSF001109 (SAHH)
5. cd00401 (SAHH)
  
  62 - 467
  
  CDD
  cd00401 (SAHH)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  238 - 397
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
2. G3DSA:3.40.50...
  
  277 - 379
  
  GENE3D
  G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
IPR015878

S-adenosyl-L-homocysteine hydrolase, NAD binding domain
1. SM00997 (AdoHcyase_...)
  
  238 - 399
  
  SMART
  SM00997 (AdoHcyase_NAD_2)
2. PF00670 (AdoHcyase_NAD)
  
  238 - 398
  
  Pfam
  PF00670 (AdoHcyase_NAD)
IPR020082

S-adenosyl-L-homocysteine hydrolase, conserved site
1. PS00739 (ADOHCYASE_2)
  
  260 - 276
  
  PROSITE patterns
  PS00739 (ADOHCYASE_2)
2. PS00738 (ADOHCYASE_1)
  
  124 - 138
  
  PROSITE patterns
  PS00738 (ADOHCYASE_1)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

399 - 479

GENE3D
G3DSA:3.40.50.1480 (G3DSA:3.40.50.1480)

51 - 276

GENE3D
G3DSA:3.40.50.1480 (G3DSA:3.40.50.1480)
SSF52283 (Formate/g...)

51 - 237

SUPERFAMILY
SSF52283 (Formate/glycerate dehydrogenase catalytic domain-like)

399 - 479

SUPERFAMILY
SSF52283 (Formate/glycerate dehydrogenase catalytic domain-like)
mobidb-lite (disord...)

1 - 51

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

homotetramer inter...

63F

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

66R

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

70I

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

73Q

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

74E

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

209H

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

212Y

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

213Q

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

229D

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

231V

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

235K

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

236F

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

240Y

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

243R

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

244E

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

248D

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

251K

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

252R

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

255D

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

256L

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

257M

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

258F

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

259G

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

260G

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

261K

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

269G

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

270E

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

273K

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

282L

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

283G

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

285V

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

290E

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

291I

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

292D

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

293P

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

294I

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

295C

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

296A

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

297L

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

298Q

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

300A

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

301M

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

302D

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

303G

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

305R

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

306V

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

307V

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

308K

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

311E

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

324G

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

325N

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

326K

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

327G

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

328V

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

338K

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

339N

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

340G

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

351T

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

368V

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

369R

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

374H

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

397S

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

400P

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

402F

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

403V

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

406V

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

432L

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

438D

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

439E

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

442A

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

443S

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

446L

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

449F

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

450D

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

452H

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

453L

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

454T

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

456L

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

459E

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

460Q

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

463Y

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)

464L

homotetramer interface
63F, 66R, 70I, 73Q, 74E, 209H, 212Y, 213Q, 229D, 231V, 235K, 236F, 240Y, 243R, 244E, 248D, 251K, 252R, 255D, 256L, 257M, 258F, 259G, 260G, 261K, 269G, 270E, 273K, 282L, 283G, 285V, 290E, 291I, 292D, 293P, 294I, 295C, 296A, 297L, 298Q, 300A, 301M, 302D, 303G, 305R, 306V, 307V, 308K, 311E, 324G, 325N, 326K, 327G, 328V, 338K, 339N, 340G, 351T, 368V, 369R, 374H, 397S, 400P, 402F, 403V, 406V, 432L, 438D, 439E, 442A, 443S, 446L, 449F, 450D, 452H, 453L, 454T, 456L, 459E, 460Q, 463Y, 464L
CDD
cd00401 (SAHH)
catalytic site cd0...

101H

catalytic site
101H, 178D, 203E, 237D
CDD
cd00401 (SAHH)

178D

catalytic site
101H, 178D, 203E, 237D
CDD
cd00401 (SAHH)

203E

catalytic site
101H, 178D, 203E, 237D
CDD
cd00401 (SAHH)

237D

catalytic site
101H, 178D, 203E, 237D
CDD
cd00401 (SAHH)
ligand binding sit...

101H

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

103N

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

105Q

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

106T

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

178D

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

203E

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

204S

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

233K

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

237D

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

394L

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

398S

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

399L

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

404V

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)

408A

ligand binding site
101H, 103N, 105Q, 106T, 178D, 203E, 204S, 233K, 237D, 394L, 398S, 399L, 404V, 408A
CDD
cd00401 (SAHH)
NAD binding site c...

204S

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

205V

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

206T

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

238N

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

242C

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

267G

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

269G

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

270E

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

271V

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

289T

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

290E

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

291I

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

292D

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

295C

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

322A

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

323T

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

324G

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

325N

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

328V

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

346M

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

347G

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

348H

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

391L

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

393N

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

399L

NAD binding site
204S, 205V, 206T, 238N, 242C, 267G, 269G, 270E, 271V, 289T, 290E, 291I, 292D, 295C, 322A, 323T, 324G, 325N, 328V, 346M, 347G, 348H, 391L, 393N, 399L
CDD
cd00401 (SAHH)

GO term prediction

Biological Process

GO:0006730 one-carbon metabolic process
GO:0019510 S-adenosylhomocysteine catabolic process

Molecular Function

GO:0004013 adenosylhomocysteinase activity
GO:0051287 NAD binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features