KWMTBOMO00328

Protein

Length

576 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
92 - 335
Ras guanine nucleotide exchange factor domain (IPR023578)
Domain
99 - 335
Ras guanine-nucleotide exchange factors catalytic domain (IPR001895)
452 - 573
PH domain-like (IPR011993)
Pleckstrin homology domain (IPR001849)

1 100 200 300 400 500 576

Detailed signature matches

IPR023578

Ras guanine nucleotide exchange factor domain
1. SSF48366 (Ras GEF)
  
  92 - 335
  
  SUPERFAMILY
  SSF48366 (Ras GEF)
IPR001895

Ras guanine-nucleotide exchange factors catalytic domain
1. PF00617 (RasGEF)
  
  107 - 270
  
  Pfam
  PF00617 (RasGEF)
2. cd00155 (RasGEF)
  
  100 - 330
  
  CDD
  cd00155 (RasGEF)
3. G3DSA:1.10.84...
  
  99 - 317
  
  GENE3D
  G3DSA:1.10.840.10 (G3DSA:1.10.840.10)
4. PS50009 (RASGEF_CAT)
  
  103 - 334
  
  PROSITE profiles
  PS50009 (RASGEF_CAT)
5. SM00147 (RasGEF_3)
  
  99 - 335
  
  SMART
  SM00147 (RasGEF_3)
IPR011993

PH domain-like
1. G3DSA:2.30.29.30
  
  455 - 559
  
  GENE3D
  G3DSA:2.30.29.30 (G3DSA:2.30.29.30)
2. SSF50729 (PH domain...)
  
  452 - 573
  
  SUPERFAMILY
  SSF50729 (PH domain-like)
IPR001849

Pleckstrin homology domain
1. PS50003 (PH_DOMAIN)
  
  462 - 562
  
  PROSITE profiles
  PS50003 (PH_DOMAIN)
2. SM00233 (PH_update)
  
  452 - 564
  
  SMART
  SM00233 (PH_update)
3. PF00169 (PH)
  
  458 - 560
  
  Pfam
  PF00169 (PH)

Residue annotation

Ras interaction si...

132W

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

133T

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

134K

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

144V

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

145V

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

147F

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

148T

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

149K

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

151F

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

152N

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

155S

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

156F

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

159V

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

192H

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

195F

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

196A

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

198I

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

199S

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

200A

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

202H

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

203S

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

204A

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

205S

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

207Y

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

208R

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

228A

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

231F

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

236N

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

237W

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

238T

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

241R

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

254Y

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

255L

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

256G

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

259L

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

260T

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

261D

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

263V

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

264Y

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

265I

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

267I

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

268A

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

269H

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

270P

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

282I

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

286A

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

322D

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

325Y

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

326K

Ras interaction site
132W, 133T, 134K, 144V, 145V, 147F, 148T, 149K, 151F, 152N, 155S, 156F, 159V, 192H, 195F, 196A, 198I, 199S, 200A, 202H, 203S, 204A, 205S, 207Y, 208R, 228A, 231F, 236N, 237W, 238T, 241R, 254Y, 255L, 256G, 259L, 260T, 261D, 263V, 264Y, 265I, 267I, 268A, 269H, 270P, 282I, 286A, 322D, 325Y, 326K
CDD
cd00155 (RasGEF)

GO term prediction

Biological Process

GO:0007264 small GTPase mediated signal transduction

Molecular Function

GO:0005085 guanyl-nucleotide exchange factor activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

KWMTBOMO00328

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component