KWMTBOMO00323

Protein

Length

3,694 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
409 - 848
Dynein heavy chain, domain-2 (IPR013602)
1,015 - 1,211
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
1,231 - 1,451
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
1,634 - 1,899
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
1,972 - 2,090
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
2,122 - 2,236
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
2,245 - 2,573
Dynein heavy chain, coiled coil stalk (IPR024743)
2,965 - 3,689
Dynein heavy chain domain (IPR004273)
Domain
1,299 - 1,443
ATPase, dynein-related, AAA domain (IPR011704)
1,970 - 2,232
Dynein heavy chain, P-loop containing D4 domain (IPR024317)

1 500 1000 1500 2000 2500 3000 3694

Detailed signature matches

IPR013602

Dynein heavy chain, domain-2
1. PF08393 (DHC_N2)
  
  409 - 848
  
  Pfam
  PF08393 (DHC_N2)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  1,973 - 2,090
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  2,122 - 2,236
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,639 - 1,899
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,020 - 1,211
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,231 - 1,451
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
2. G3DSA:3.40.50...
  
  1,022 - 1,160
  
  GENE3D
  G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
  
  1,634 - 1,809
  
  GENE3D
  G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
  
  1,233 - 1,451
  
  GENE3D
  G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
  
  1,972 - 2,090
  
  GENE3D
  G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
  
  2,122 - 2,179
  
  GENE3D
  G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
IPR003593

AAA+ ATPase domain
1. SM00382 (AAA_5)
  
  1,639 - 1,787
  
  SMART
  SM00382 (AAA_5)
  
  1,015 - 1,154
  
  SMART
  SM00382 (AAA_5)
IPR011704

ATPase, dynein-related, AAA domain
1. PF07728 (AAA_5)
  
  1,299 - 1,443
  
  Pfam
  PF07728 (AAA_5)
IPR024317

Dynein heavy chain, P-loop containing D4 domain
1. PF12780 (AAA_8)
  
  1,970 - 2,232
  
  Pfam
  PF12780 (AAA_8)
IPR024743

Dynein heavy chain, coiled coil stalk
1. PF12777 (MT)
  
  2,245 - 2,573
  
  Pfam
  PF12777 (MT)
IPR004273

Dynein heavy chain domain
1. PF03028 (Dynein_heavy)
  
  2,965 - 3,689
  
  Pfam
  PF03028 (Dynein_heavy)

no IPR

Unintegrated signatures

Coil

2,306 - 2,326

COILS
Coil (Coil)

267 - 287

COILS
Coil (Coil)

368 - 388

COILS
Coil (Coil)

2,811 - 2,834

COILS
Coil (Coil)

2,466 - 2,514

COILS
Coil (Coil)
PF12774 (AAA_6)

985 - 1,215

Pfam
PF12774 (AAA_6)
PF12775 (AAA_7)

1,608 - 1,879

Pfam
PF12775 (AAA_7)
PF12781 (AAA_9)

2,603 - 2,822

Pfam
PF12781 (AAA_9)
cd00009 (AAA)

1,637 - 1,783

CDD
cd00009 (AAA)

Residue annotation

Walker A motif cd0...

1,647G

Walker A motif
1,647G, 1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T
CDD
cd00009 (AAA)

1,648N

Walker A motif
1,647G, 1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T
CDD
cd00009 (AAA)

1,649T

Walker A motif
1,647G, 1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T
CDD
cd00009 (AAA)

1,650G

Walker A motif
1,647G, 1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T
CDD
cd00009 (AAA)

1,651V

Walker A motif
1,647G, 1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T
CDD
cd00009 (AAA)

1,652G

Walker A motif
1,647G, 1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T
CDD
cd00009 (AAA)

1,653K

Walker A motif
1,647G, 1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T
CDD
cd00009 (AAA)

1,654T

Walker A motif
1,647G, 1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T
CDD
cd00009 (AAA)
ATP binding site c...

1,648N

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)

1,649T

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)

1,650G

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)

1,651V

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)

1,652G

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)

1,653K

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)

1,654T

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)

1,655C

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)

1,715D

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)

1,762S

ATP binding site
1,648N, 1,649T, 1,650G, 1,651V, 1,652G, 1,653K, 1,654T, 1,655C, 1,715D, 1,762S
CDD
cd00009 (AAA)
Walker B motif cd0...

1,711I

Walker B motif
1,711I, 1,712I, 1,713F, 1,714I, 1,715D, 1,716D
CDD
cd00009 (AAA)

1,712I

Walker B motif
1,711I, 1,712I, 1,713F, 1,714I, 1,715D, 1,716D
CDD
cd00009 (AAA)

1,713F

Walker B motif
1,711I, 1,712I, 1,713F, 1,714I, 1,715D, 1,716D
CDD
cd00009 (AAA)

1,714I

Walker B motif
1,711I, 1,712I, 1,713F, 1,714I, 1,715D, 1,716D
CDD
cd00009 (AAA)

1,715D

Walker B motif
1,711I, 1,712I, 1,713F, 1,714I, 1,715D, 1,716D
CDD
cd00009 (AAA)

1,716D

Walker B motif
1,711I, 1,712I, 1,713F, 1,714I, 1,715D, 1,716D
CDD
cd00009 (AAA)
arginine finger cd...

1,776R

arginine finger
1,776R
CDD
cd00009 (AAA)

GO term prediction

Biological Process

GO:0007018 microtubule-based movement

Molecular Function

GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0016887 ATPase activity

Cellular Component

GO:0030286 dynein complex

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Entry type

Status

Per-residue features