KWMTBOMO00277

Protein

Length

480 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
28 - 474
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 480

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  29 - 419
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. cd06174 (MFS)
  
  95 - 457
  
  CDD
  cd06174 (MFS)
2. SSF103473 (MFS gene...)
  
  28 - 474
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

276 - 468

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

29 - 240

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

98A

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

99F

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

101L

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

102G

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

153G

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

154A

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

159F

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

160A

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

163F

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

164A

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

167A

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

179V

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

180G

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

187L

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

188S

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

194I

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

289Y

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

292Q

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

297Q

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

300Y

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

301L

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

304Q

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

318K

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

322S

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

326V

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

329M

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

333I

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

379A

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

382P

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

385A

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

389R

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

390S

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

393S

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

404A

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

405Y

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

408L

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

409S

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

412E

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

413N

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

416A

putative substrate translocation pore
98A, 99F, 101L, 102G, 153G, 154A, 159F, 160A, 163F, 164A, 167A, 179V, 180G, 187L, 188S, 194I, 289Y, 292Q, 297Q, 300Y, 301L, 304Q, 318K, 322S, 326V, 329M, 333I, 379A, 382P, 385A, 389R, 390S, 393S, 404A, 405Y, 408L, 409S, 412E, 413N, 416A
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

KWMTBOMO00277

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component