KWMTBOMO00249

Protein

Length

811 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
10 - 294
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
713 - 744
Serine/threonine-protein kinase OSR1/WNK, CCT domain (IPR024678)

1 100 200 300 400 500 600 700 811

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  10 - 294
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. SM00220 (serkin_6)
  
  19 - 293
  
  SMART
  SM00220 (serkin_6)
2. PS50011 (PROTEIN_KI...)
  
  19 - 293
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
3. PF00069 (Pkinase)
  
  19 - 293
  
  Pfam
  PF00069 (Pkinase)
IPR024678

Serine/threonine-protein kinase OSR1/WNK, CCT domain
1. PF12202 (OSR1_C)
  
  713 - 744
  
  Pfam
  PF12202 (OSR1_C)
IPR017441

Protein kinase, ATP binding site
1. PS00107 (PROTEIN_KI...)
  
  25 - 48
  
  PROSITE patterns
  PS00107 (PROTEIN_KINASE_ATP)

no IPR

Unintegrated signatures

Coil

490 - 510

COILS
Coil (Coil)
G3DSA:1.10.51...

82 - 301

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.10.20.90

712 - 809

GENE3D
G3DSA:3.10.20.90 (G3DSA:3.10.20.90)
G3DSA:3.30.20...

7 - 81

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd06610 (STKc_OSR1_...)

17 - 293

CDD
cd06610 (STKc_OSR1_SPAK)
mobidb-lite (disord...)

317 - 453

MobiDB Lite
mobidb-lite (disorder_prediction)

600 - 703

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

25I

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

26G

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

27V

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

28G

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

29A

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

33V

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

46A

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

48K

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

78V

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

94L

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

95K

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

96L

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

97L

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

100G

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

101S

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

104D

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

150K

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

152G

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

153N

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

155L

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)

166D

ATP binding site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 150K, 152G, 153N, 155L, 166D
CDD
cd06610 (STKc_OSR1_SPAK)
active site cd06610

25I

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

26G

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

27V

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

28G

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

29A

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

33V

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

46A

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

48K

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

78V

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

94L

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

95K

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

96L

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

97L

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

100G

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

101S

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

104D

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

148D

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

150K

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

151A

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

152G

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

153N

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

155L

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

165A

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

166D

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

169V

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

188F

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

189V

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

190G

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

191T

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

193C

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

221E

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

230H

active site
25I, 26G, 27V, 28G, 29A, 33V, 46A, 48K, 78V, 94L, 95K, 96L, 97L, 100G, 101S, 104D, 148D, 150K, 151A, 152G, 153N, 155L, 165A, 166D, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)
polypeptide substr...

28G

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

29A

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

148D

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

150K

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

151A

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

152G

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

169V

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

188F

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

189V

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

190G

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

191T

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

193C

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

221E

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)

230H

polypeptide substrate binding site
28G, 29A, 148D, 150K, 151A, 152G, 169V, 188F, 189V, 190G, 191T, 193C, 221E, 230H
CDD
cd06610 (STKc_OSR1_SPAK)
dimer interface cd...

149V

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

150K

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

174A

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

175T

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

176G

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

189V

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

190G

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

191T

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

192P

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

193C

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

194W

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

195M

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

196A

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

197P

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

198E

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

199V

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

200M

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

201E

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

202Q

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

204H

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

205G

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

206Y

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

210A

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

213W

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

214S

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

217I

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

218T

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

221E

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

227A

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

234P

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

237V

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

238L

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

239M

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

241T

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

242L

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

276K

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

278P

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

279T

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)

281R

dimer interface
149V, 150K, 174A, 175T, 176G, 189V, 190G, 191T, 192P, 193C, 194W, 195M, 196A, 197P, 198E, 199V, 200M, 201E, 202Q, 204H, 205G, 206Y, 210A, 213W, 214S, 217I, 218T, 221E, 227A, 234P, 237V, 238L, 239M, 241T, 242L, 276K, 278P, 279T, 281R
CDD
cd06610 (STKc_OSR1_SPAK)
activation loop (A...

165A

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

166D

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

167F

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

168G

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

169V

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

170S

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

171A

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

172W

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

173L

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

174A

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

175T

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

176G

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

177R

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

178D

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

185R

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

186H

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

187T

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

188F

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

189V

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

190G

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

191T

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

192P

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

193C

activation loop (A-loop)
165A, 166D, 167F, 168G, 169V, 170S, 171A, 172W, 173L, 174A, 175T, 176G, 177R, 178D, 185R, 186H, 187T, 188F, 189V, 190G, 191T, 192P, 193C
CDD
cd06610 (STKc_OSR1_SPAK)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component