Protein

KWMTBOMO00228

Length
543 amino acids

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 543

Detailed signature matches

  1. Family IPR001273
    Aromatic amino acid hydroxylase
    1. G3DSA:1.10.80...
  2. Family IPR019773
    Tyrosine 3-monooxygenase-like
    1. PIRSF000336 (TH)
  3. Family IPR005963
    Tryptophan 5-monooxygenase
    1. TIGR01270
  4. Domain IPR002912
    ACT domain
    1. PS51671 (ACT)
  5. Domain IPR019774
    Aromatic amino acid hydroxylase, C-terminal
    1. SSF56534 (Aromatic ...)
    2. PS51410 (BH4_AAA_HY...)
    3. PR00372 (FYWHYDRXLASE)
    4. PF00351 (Biopterin_H)
  6. SITE IPR018301
    Aromatic amino acid hydroxylase, iron/copper binding site
    1. PS00367 (BH4_AAA_HY...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF55021 (ACT-like)
  2. cd03346 (eu_TrpOH)
  3. mobidb-lite (disord...)

Residue annotation

  1. cofactor binding s...
  2. metal binding site...

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0009072 aromatic amino acid family metabolic process
GO:0042427 serotonin biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004497 monooxygenase activity
GO:0004510 tryptophan 5-monooxygenase activity
GO:0005506 iron ion binding
GO:0016597 amino acid binding
GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

Cellular Component

None predicted.