KWMTBOMO00113

Protein

Length

573 amino acids

Protein family membership

Major facilitator, sugar transporter-like (IPR005828)

Domains and repeats

Domain
100 - 537
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 573

Detailed signature matches

IPR005828

Major facilitator, sugar transporter-like
1. PF00083 (Sugar_tr)
  
  158 - 535
  
  Pfam
  PF00083 (Sugar_tr)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  100 - 533
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  162 - 529
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  147 - 537
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
IPR005829

Sugar transporter, conserved site
1. PS00216 (SUGAR_TRAN...)
  
  411 - 427
  
  PROSITE patterns
  PS00216 (SUGAR_TRANSPORT_1)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

348 - 535

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

159 - 303

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

166Q

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

169F

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

170F

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

173S

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

177G

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

178F

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

180I

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

181G

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

227Y

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

228D

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

231M

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

232M

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

235Y

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

236L

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

239L

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

252N

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

253L

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

256S

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

257I

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

263V

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

376Y

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

379Y

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

380D

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

383I

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

384R

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

387S

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

397F

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

401S

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

404E

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

408I

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

455R

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

458V

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

459N

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

462L

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

466M

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

467Q

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

470A

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

481G

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

482T

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

485I

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

486H

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

489G

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

490Y

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

493T

putative substrate translocation pore
166Q, 169F, 170F, 173S, 177G, 178F, 180I, 181G, 227Y, 228D, 231M, 232M, 235Y, 236L, 239L, 252N, 253L, 256S, 257I, 263V, 376Y, 379Y, 380D, 383I, 384R, 387S, 397F, 401S, 404E, 408I, 455R, 458V, 459N, 462L, 466M, 467Q, 470A, 481G, 482T, 485I, 486H, 489G, 490Y, 493T
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity
GO:0022857 transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features