Protein

KWMTBOMO00022

Length
1,006 amino acids

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1006

Detailed signature matches

  1. Family IPR016257
    Ephrin receptor type-A /type-B
    1. PIRSF000666 (TyrPK_...)
  2. Domain IPR008979
    Galactose-binding domain-like
    1. G3DSA:2.60.12...
    2. SSF49785 (Galactose...)
  3. Domain IPR001090
    Ephrin receptor ligand binding domain
    1. PF01404 (Ephrin_lbd)
    2. SM00615 (eph)
    3. PS51550 (EPH_LBD)
  4. Domain IPR011641
    Tyrosine-protein kinase ephrin type A/B receptor-like
    1. SM01411 (GCC2_GCC3_2)
  5. Domain IPR013783
    Immunoglobulin-like fold
    1. G3DSA:2.60.40.10
  6. Domain IPR003961
    Fibronectin type III
    1. cd00063 (FN3)
    2. SM00060 (FN3_2)
    3. PF00041 (fn3)
    4. SSF49265 (Fibronect...)
    5. PS50853 (FN3)
  7. Domain IPR027936
    Ephrin receptor, transmembrane domain
    1. PF14575 (EphA2_TM)
  8. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  9. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
  10. Domain IPR001245
    Serine-threonine/tyrosine-protein kinase catalytic domain
    1. PR00109 (TYRKINASE)
    2. PF07714 (Pkinase_Tyr)
  11. Domain IPR020635
    Tyrosine-protein kinase, catalytic domain
    1. SM00219 (tyrkin_6)
  12. Domain IPR013761
    Sterile alpha motif/pointed domain
    1. SSF47769 (SAM/Point...)
    2. G3DSA:1.10.15...
  13. Domain IPR001660
    Sterile alpha motif domain
    1. PF00536 (SAM_1)
    2. SM00454 (SAM_4)
    3. PS50105 (SAM_DOMAIN)
  14. SITE IPR001426
    Tyrosine-protein kinase, receptor class V, conserved site
    1. PS00790 (RECEPTOR_T...)
  15. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  16. SITE IPR008266
    Tyrosine-protein kinase, active site
    1. PS00109 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:2.170.3...
  3. G3DSA:3.30.20...
  4. cd05033 (PTKc_EphR)
  5. cd09488 (SAM_EPH-R)
  6. cd10319 (EphR_LBD)

Residue annotation

  1. ephrin binding sit...
  2. Interdomain contac...
  3. Cytokine receptor ...
  4. Interdomain contac...
  5. Cytokine receptor ...
  6. ATP binding site c...
  7. active site cd05033
  8. polypeptide substr...
  9. activation loop (A...
  10. putative phosphory...

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0048013 ephrin receptor signaling pathway

Molecular Function

GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005003 ephrin receptor activity
GO:0005515 protein binding
GO:0005524 ATP binding

Cellular Component

GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane