Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002034-TA|BGIBMGA002034-PA|IPR007110|Immunoglobulin-
like, IPR003599|Immunoglobulin subtype, IPR003598|Immunoglobulin
subtype 2, IPR013098|Immunoglobulin I-set
(3063 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 108 4e-22
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 108 4e-22
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop... 108 4e-22
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 108 4e-22
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 107 6e-22
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr... 107 6e-22
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 105 3e-21
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 104 4e-21
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 98 4e-19
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 98 4e-19
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 98 4e-19
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 98 5e-19
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 98 5e-19
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 98 5e-19
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 98 5e-19
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 93 1e-17
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 93 1e-17
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 93 1e-17
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 93 2e-17
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 92 3e-17
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 92 3e-17
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 92 3e-17
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 92 3e-17
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 92 3e-17
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 92 3e-17
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 92 3e-17
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 92 3e-17
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 91 6e-17
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 89 2e-16
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 89 2e-16
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 89 2e-16
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 89 2e-16
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 89 2e-16
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 88 4e-16
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 88 4e-16
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 85 3e-15
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 85 3e-15
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 85 3e-15
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 85 3e-15
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 85 5e-15
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 84 9e-15
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 83 1e-14
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 83 1e-14
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 82 4e-14
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 80 1e-13
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 80 1e-13
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 80 1e-13
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 80 1e-13
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 80 1e-13
AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein. 79 2e-13
BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein. 77 1e-12
BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein. 77 1e-12
BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein. 77 1e-12
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p... 77 1e-12
AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein. 77 1e-12
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 77 1e-12
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 77 1e-12
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 77 1e-12
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 76 2e-12
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 75 3e-12
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 75 3e-12
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 75 3e-12
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 75 3e-12
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 75 3e-12
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 75 3e-12
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 75 3e-12
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 75 5e-12
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 75 5e-12
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 75 5e-12
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 75 5e-12
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 75 5e-12
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 75 5e-12
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 75 5e-12
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 75 5e-12
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 75 5e-12
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 75 5e-12
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 75 5e-12
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 75 5e-12
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 73 1e-11
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 73 2e-11
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 72 4e-11
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p... 71 9e-11
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p... 71 9e-11
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 70 1e-10
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 70 1e-10
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 70 1e-10
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 70 1e-10
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 70 1e-10
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 70 1e-10
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 70 1e-10
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 70 1e-10
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 70 1e-10
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 70 1e-10
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 69 3e-10
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 69 3e-10
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 69 3e-10
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 69 3e-10
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 69 3e-10
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 69 3e-10
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 69 3e-10
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 69 3e-10
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 69 3e-10
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 69 4e-10
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 68 5e-10
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 67 8e-10
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 67 8e-10
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 67 8e-10
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 67 8e-10
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 66 2e-09
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 65 4e-09
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 65 4e-09
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 65 4e-09
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 65 4e-09
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 65 4e-09
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 65 4e-09
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 65 4e-09
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 65 4e-09
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 65 4e-09
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 65 4e-09
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 64 1e-08
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 64 1e-08
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 62 3e-08
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform... 62 4e-08
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform... 62 4e-08
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein. 62 4e-08
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 62 4e-08
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 62 4e-08
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 61 5e-08
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 60 1e-07
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 60 1e-07
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 60 1e-07
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 60 1e-07
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 60 2e-07
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 60 2e-07
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 60 2e-07
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 60 2e-07
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 60 2e-07
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 60 2e-07
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 59 2e-07
AK092284-1|BAC03850.1| 885|Homo sapiens protein ( Homo sapiens ... 59 2e-07
AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein. 59 2e-07
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 58 5e-07
BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein pr... 58 5e-07
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 58 5e-07
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 58 5e-07
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 58 7e-07
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 58 7e-07
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 58 7e-07
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 58 7e-07
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 58 7e-07
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 58 7e-07
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 58 7e-07
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 58 7e-07
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 58 7e-07
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 58 7e-07
BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein pr... 57 9e-07
AJ314900-1|CAC85747.1| 551|Homo sapiens obscurin protein. 57 1e-06
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 57 1e-06
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 56 2e-06
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 56 2e-06
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 56 2e-06
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 56 2e-06
BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein. 56 3e-06
BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein. 56 3e-06
BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein. 55 4e-06
AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine phosp... 55 4e-06
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 55 4e-06
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 55 5e-06
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 55 5e-06
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 54 6e-06
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 54 6e-06
BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein. 54 6e-06
BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein. 54 6e-06
BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kin... 54 6e-06
BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kin... 54 6e-06
BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kin... 54 6e-06
BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kin... 54 6e-06
AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein ... 54 6e-06
AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein ... 54 6e-06
AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein ... 54 6e-06
AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein ... 54 6e-06
AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle... 54 6e-06
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 54 6e-06
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 54 8e-06
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 54 8e-06
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 54 8e-06
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 54 8e-06
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 54 8e-06
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 54 8e-06
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 54 8e-06
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 54 8e-06
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 54 8e-06
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 54 8e-06
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 54 8e-06
AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein. 54 8e-06
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 54 8e-06
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 54 1e-05
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 53 1e-05
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 53 1e-05
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 53 1e-05
AJ314898-1|CAC85746.1| 646|Homo sapiens obscurin protein. 53 2e-05
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari... 53 2e-05
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 52 2e-05
AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein pr... 52 2e-05
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 52 3e-05
AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific tit... 52 3e-05
AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein. 52 3e-05
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 52 4e-05
AK096458-1|BAC04796.1| 410|Homo sapiens protein ( Homo sapiens ... 51 6e-05
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 51 6e-05
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 51 8e-05
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 50 1e-04
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 50 1e-04
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 50 1e-04
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 50 1e-04
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 50 1e-04
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 50 1e-04
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 50 1e-04
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 50 1e-04
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 50 1e-04
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 50 1e-04
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 50 1e-04
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein. 50 1e-04
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 50 1e-04
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 50 1e-04
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 50 1e-04
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 50 1e-04
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 50 1e-04
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 50 1e-04
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 50 1e-04
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 50 1e-04
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 50 1e-04
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 50 1e-04
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 50 1e-04
M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth fa... 50 1e-04
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 50 1e-04
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 50 1e-04
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 50 1e-04
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 50 1e-04
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 50 1e-04
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 50 1e-04
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 50 1e-04
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 50 1e-04
BC046109-1|AAH46109.1| 459|Homo sapiens PTK7 protein protein. 50 1e-04
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 50 1e-04
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 50 1e-04
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 50 1e-04
AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens ... 50 1e-04
AJ314905-1|CAC85752.1| 2212|Homo sapiens obscurin protein. 50 1e-04
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 50 1e-04
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 50 1e-04
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 50 1e-04
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 50 1e-04
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 50 1e-04
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 50 1e-04
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 50 1e-04
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 50 1e-04
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 50 1e-04
AB046776-1|BAB13382.1| 1596|Homo sapiens KIAA1556 protein protein. 50 1e-04
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 50 2e-04
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 50 2e-04
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 50 2e-04
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 50 2e-04
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 50 2e-04
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 50 2e-04
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 50 2e-04
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei... 50 2e-04
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei... 50 2e-04
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 50 2e-04
BC038515-1|AAH38515.1| 796|Homo sapiens CCDC110 protein protein. 49 2e-04
BC028419-1|AAH28419.1| 833|Homo sapiens coiled-coil domain cont... 49 2e-04
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 49 2e-04
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 49 2e-04
AB080722-1|BAC81776.1| 833|Homo sapiens hypothetical protein pr... 49 2e-04
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 49 3e-04
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 49 3e-04
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 49 3e-04
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 49 3e-04
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 49 3e-04
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 49 3e-04
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 49 3e-04
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 49 3e-04
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 48 4e-04
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 48 4e-04
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 48 4e-04
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 48 4e-04
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 48 4e-04
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 48 4e-04
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 48 5e-04
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 48 5e-04
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 48 5e-04
U11814-1|AAA68514.1| 366|Homo sapiens soluble keratinocyte grow... 48 5e-04
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 48 5e-04
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 48 5e-04
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 48 5e-04
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 48 5e-04
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 48 5e-04
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 48 5e-04
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 48 5e-04
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 48 5e-04
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 48 5e-04
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 48 5e-04
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 48 5e-04
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 48 5e-04
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 48 5e-04
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 48 5e-04
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 48 5e-04
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 48 5e-04
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 48 5e-04
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 48 5e-04
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 48 5e-04
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 48 5e-04
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 48 5e-04
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 48 5e-04
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 48 5e-04
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 48 5e-04
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 48 5e-04
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 48 7e-04
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 48 7e-04
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 48 7e-04
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 47 0.001
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 47 0.001
DQ248309-1|ABB55264.1| 851|Homo sapiens rhabdomyosarcoma antige... 47 0.001
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 47 0.001
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 47 0.001
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 47 0.001
AK057954-1|BAB71622.1| 505|Homo sapiens protein ( Homo sapiens ... 47 0.001
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 47 0.001
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 47 0.001
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 46 0.002
X85137-1|CAA59449.1| 1057|Homo sapiens kinesin-related protein p... 46 0.002
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 46 0.002
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 46 0.002
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 46 0.002
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 46 0.002
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 46 0.002
DQ464902-1|ABE97925.1| 675|Homo sapiens nexilin protein. 46 0.002
BC114445-1|AAI14446.1| 567|Homo sapiens NEXN protein protein. 46 0.002
BC114444-1|AAI14445.1| 567|Homo sapiens NEXN protein protein. 46 0.002
BC111395-1|AAI11396.1| 554|Homo sapiens NEXN protein protein. 46 0.002
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 46 0.002
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 46 0.002
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 46 0.002
AF114264-1|AAD29607.1| 448|Homo sapiens unknown protein. 46 0.002
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 46 0.002
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 46 0.002
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 46 0.002
AY211921-1|AAO65174.1| 294|Homo sapiens sarcoma antigen NY-SAR-... 46 0.002
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 46 0.002
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 46 0.002
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 46 0.002
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 46 0.002
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 46 0.002
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 46 0.003
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 46 0.003
BC115397-1|AAI15398.1| 867|Homo sapiens IGSF22 protein protein. 46 0.003
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 46 0.003
AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens ... 46 0.003
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 45 0.004
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 45 0.005
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 45 0.005
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 45 0.005
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 45 0.005
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 45 0.005
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 45 0.005
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 44 0.007
BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein ... 44 0.007
AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein ... 44 0.007
AF063308-1|AAD02813.1| 1120|Homo sapiens coiled-coil related pro... 44 0.007
CR457157-1|CAG33438.1| 442|Homo sapiens IGSF4 protein. 44 0.009
BX640951-1|CAE45975.1| 370|Homo sapiens hypothetical protein pr... 44 0.009
BC125103-1|AAI25104.1| 414|Homo sapiens CADM1 protein protein. 44 0.009
BC125102-1|AAI25103.1| 415|Homo sapiens CADM1 protein protein. 44 0.009
BC047021-1|AAH47021.1| 387|Homo sapiens CADM1 protein protein. 44 0.009
AY358334-1|AAQ88700.1| 440|Homo sapiens IGSF4 protein. 44 0.009
AK075502-1|BAC11657.1| 443|Homo sapiens protein ( Homo sapiens ... 44 0.009
AF190637-1|AAG17141.1| 1241|Homo sapiens nephrin protein. 44 0.009
AF132811-1|AAF69029.1| 442|Homo sapiens nectin-like protein 2 p... 44 0.009
AF035835-1|AAC39687.1| 1241|Homo sapiens nephrin protein. 44 0.009
AB094146-1|BAC66178.1| 333|Homo sapiens secretory isoform of TS... 44 0.009
AB017563-1|BAA75822.1| 442|Homo sapiens IGSF4 protein. 44 0.009
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 44 0.011
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 44 0.011
U37426-1|AAA86132.1| 1056|Homo sapiens kinesin-like spindle prot... 44 0.011
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 44 0.011
BC126211-1|AAI26212.1| 1056|Homo sapiens kinesin family member 1... 44 0.011
AL360222-1|CAH72288.1| 1056|Homo sapiens kinesin family member 1... 44 0.011
AL356128-3|CAI13671.1| 1056|Homo sapiens kinesin family member 1... 44 0.011
AC115538-1|AAY40987.1| 103|Homo sapiens unknown protein. 44 0.011
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 43 0.015
M34187-1|AAA35838.1| 302|Homo sapiens protein ( Human fibroblas... 43 0.015
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 43 0.015
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 43 0.015
BC037312-1|AAH37312.1| 517|Homo sapiens ATF7IP protein protein. 43 0.015
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 43 0.015
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 43 0.015
AK223126-1|BAD96846.1| 300|Homo sapiens fibroblast growth facto... 43 0.015
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 43 0.015
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 43 0.015
AF345347-1|AAL06396.2| 1135|Homo sapiens mitotic spindle-associa... 43 0.015
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein. 43 0.015
>AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein
protein.
Length = 1320
Score = 108 bits (259), Expect = 4e-22
Identities = 97/307 (31%), Positives = 135/307 (43%), Gaps = 44/307 (14%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVY-----QLTGTNSL----------G 152
+TE V+F CK+VG P P + WFKDG+++ + + + GT SL G
Sbjct: 956 VTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDG 1015
Query: 153 SYCCIAKNCMGQASSSAELTVEDI---------------QNQLNEEEKLQLFSKNQAPKF 197
+Y +A N G+ S S L V+ + ++++ E +K L + P F
Sbjct: 1016 NYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHF 1075
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
+ + A R KV+ P P L W + QPV + + E GV L I
Sbjct: 1076 LQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDP 1135
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKV 316
L D +KC+A N GQ+ S L ++ K P LE LQ EG V LEC+V
Sbjct: 1136 LTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV 1195
Query: 317 IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT---CSL---------GTYTCEASNCMGV 364
IG+P PV W KD E + P RI QD T C L G YT A N G+
Sbjct: 1196 IGMPPPVFYWKKDNETI-PCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGI 1254
Query: 365 AASSASL 371
+ +A L
Sbjct: 1255 VSCTARL 1261
Score = 59.3 bits (137), Expect = 2e-07
Identities = 58/211 (27%), Positives = 94/211 (44%), Gaps = 31/211 (14%)
Query: 93 KNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
+ + +P F++ ++ EG L +CKV G P P L+W +GQ + P +++ TG
Sbjct: 1068 ERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETG 1127
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKF 197
+SL G+Y CIA N GQ S S EL+V + +E K +AP
Sbjct: 1128 VHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV------VAKEVK-------KAPVI 1174
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQ 256
+ L++ P R +V P P W +D++ + R + ++ G L IQ
Sbjct: 1175 LEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQ 1234
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + A N+ G + SC +L I
Sbjct: 1235 PAKKSDAGWYTLSAKNEAG--IVSCTARLDI 1263
Score = 54.0 bits (124), Expect = 8e-06
Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQDGTCSL 351
PRF + L++ EG V L+C V+G+P P ++WY +G+EL+ DIH + +G + ++
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 352 --------GTYTCEASNCMGVAASSASL 371
G Y+C ASN G ++SA +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEI 356
Score = 51.6 bits (118), Expect = 4e-05
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 15/126 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG 147
PRF + L++ EG V +C VVG P P + W+ +G+EL + G+++ LT
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNE-EEKLQLFSKNQAPKFVHGLK 202
+ G Y C A N G S+SAE+ +E + + +E + + ++ Q P V
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 388
Query: 203 SVEAKI 208
+ A I
Sbjct: 389 TTSAVI 394
Score = 50.8 bits (116), Expect = 8e-05
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 40/218 (18%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDE-SSRCHLGKEERGVFF 252
AP F LK P FT K+ P P + W++D + + + + C + +E G
Sbjct: 944 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 1003
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ-SVTSCFLKLIIP----------RHYKKPRFLEN-- 299
L I++ D + +A N G+ S + + +P H + R E
Sbjct: 1004 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDK 1063
Query: 300 ------------LQA---ILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
LQA +++ EG + L+CKV G+P P L W +G+ + P H+++
Sbjct: 1064 EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLV 1123
Query: 344 GQDGTCSL----------GTYTCEASNCMGVAASSASL 371
+ G SL GTY C A+N G + S L
Sbjct: 1124 RETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLEL 1161
Score = 48.0 bits (109), Expect = 5e-04
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIH-RIISGQDGTCSL 351
P F + L+ EG+ V CK++G+P P + W+KDG+++ + H ++ DGTCSL
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G YT A+N G + S L+
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLM 1035
Score = 40.7 bits (91), Expect = 0.081
Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 18/96 (18%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-------ISGQ 345
P F + LQ + + EG V EC+V G P P ++WY++G ++ RI ++
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEP 494
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASL 371
+ C+L G +TC ASN G +S A L
Sbjct: 495 EEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQL 530
Score = 39.1 bits (87), Expect = 0.25
Identities = 17/50 (34%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT 146
P F + LQ + EG LV FEC+V G P+P + W+++G ++ ++++
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRIS 484
>AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1320
Score = 108 bits (259), Expect = 4e-22
Identities = 97/307 (31%), Positives = 135/307 (43%), Gaps = 44/307 (14%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVY-----QLTGTNSL----------G 152
+TE V+F CK+VG P P + WFKDG+++ + + + GT SL G
Sbjct: 956 VTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDG 1015
Query: 153 SYCCIAKNCMGQASSSAELTVEDI---------------QNQLNEEEKLQLFSKNQAPKF 197
+Y +A N G+ S S L V+ + ++++ E +K L + P F
Sbjct: 1016 NYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHF 1075
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
+ + A R KV+ P P L W + QPV + + E GV L I
Sbjct: 1076 LQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDP 1135
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKV 316
L D +KC+A N GQ+ S L ++ K P LE LQ EG V LEC+V
Sbjct: 1136 LTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV 1195
Query: 317 IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT---CSL---------GTYTCEASNCMGV 364
IG+P PV W KD E + P RI QD T C L G YT A N G+
Sbjct: 1196 IGMPPPVFYWKKDNETI-PCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGI 1254
Query: 365 AASSASL 371
+ +A L
Sbjct: 1255 VSCTARL 1261
Score = 59.3 bits (137), Expect = 2e-07
Identities = 58/211 (27%), Positives = 94/211 (44%), Gaps = 31/211 (14%)
Query: 93 KNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
+ + +P F++ ++ EG L +CKV G P P L+W +GQ + P +++ TG
Sbjct: 1068 ERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETG 1127
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKF 197
+SL G+Y CIA N GQ S S EL+V + +E K +AP
Sbjct: 1128 VHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV------VAKEVK-------KAPVI 1174
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQ 256
+ L++ P R +V P P W +D++ + R + ++ G L IQ
Sbjct: 1175 LEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQ 1234
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + A N+ G + SC +L I
Sbjct: 1235 PAKKSDAGWYTLSAKNEAG--IVSCTARLDI 1263
Score = 54.0 bits (124), Expect = 8e-06
Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQDGTCSL 351
PRF + L++ EG V L+C V+G+P P ++WY +G+EL+ DIH + +G + ++
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 352 --------GTYTCEASNCMGVAASSASL 371
G Y+C ASN G ++SA +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEI 356
Score = 51.6 bits (118), Expect = 4e-05
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 15/126 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG 147
PRF + L++ EG V +C VVG P P + W+ +G+EL + G+++ LT
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNE-EEKLQLFSKNQAPKFVHGLK 202
+ G Y C A N G S+SAE+ +E + + +E + + ++ Q P V
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 388
Query: 203 SVEAKI 208
+ A I
Sbjct: 389 TTSAVI 394
Score = 50.8 bits (116), Expect = 8e-05
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 40/218 (18%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDE-SSRCHLGKEERGVFF 252
AP F LK P FT K+ P P + W++D + + + + C + +E G
Sbjct: 944 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 1003
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ-SVTSCFLKLIIP----------RHYKKPRFLEN-- 299
L I++ D + +A N G+ S + + +P H + R E
Sbjct: 1004 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDK 1063
Query: 300 ------------LQA---ILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
LQA +++ EG + L+CKV G+P P L W +G+ + P H+++
Sbjct: 1064 EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLV 1123
Query: 344 GQDGTCSL----------GTYTCEASNCMGVAASSASL 371
+ G SL GTY C A+N G + S L
Sbjct: 1124 RETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLEL 1161
Score = 48.0 bits (109), Expect = 5e-04
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIH-RIISGQDGTCSL 351
P F + L+ EG+ V CK++G+P P + W+KDG+++ + H ++ DGTCSL
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G YT A+N G + S L+
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLM 1035
Score = 41.5 bits (93), Expect = 0.046
Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 18/96 (18%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------- 345
P F + LQ + + EG V EC+V G P P ++WY++G ++ RI+ +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASL 371
+ C+L G +TC ASN G +S A L
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQL 530
Score = 38.7 bits (86), Expect = 0.33
Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDG 134
P F + LQ + EG LV FEC+V G P+P + W+++G
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREG 472
>AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1045
Score = 108 bits (259), Expect = 4e-22
Identities = 97/307 (31%), Positives = 135/307 (43%), Gaps = 44/307 (14%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVY-----QLTGTNSL----------G 152
+TE V+F CK+VG P P + WFKDG+++ + + + GT SL G
Sbjct: 681 VTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDG 740
Query: 153 SYCCIAKNCMGQASSSAELTVEDI---------------QNQLNEEEKLQLFSKNQAPKF 197
+Y +A N G+ S S L V+ + ++++ E +K L + P F
Sbjct: 741 NYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHF 800
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
+ + A R KV+ P P L W + QPV + + E GV L I
Sbjct: 801 LQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDP 860
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKV 316
L D +KC+A N GQ+ S L ++ K P LE LQ EG V LEC+V
Sbjct: 861 LTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV 920
Query: 317 IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT---CSL---------GTYTCEASNCMGV 364
IG+P PV W KD E + P RI QD T C L G YT A N G+
Sbjct: 921 IGMPPPVFYWKKDNETI-PCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGI 979
Query: 365 AASSASL 371
+ +A L
Sbjct: 980 VSCTARL 986
Score = 59.3 bits (137), Expect = 2e-07
Identities = 58/211 (27%), Positives = 94/211 (44%), Gaps = 31/211 (14%)
Query: 93 KNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
+ + +P F++ ++ EG L +CKV G P P L+W +GQ + P +++ TG
Sbjct: 793 ERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETG 852
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKF 197
+SL G+Y CIA N GQ S S EL+V + +E K +AP
Sbjct: 853 VHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV------VAKEVK-------KAPVI 899
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQ 256
+ L++ P R +V P P W +D++ + R + ++ G L IQ
Sbjct: 900 LEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQ 959
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + A N+ G + SC +L I
Sbjct: 960 PAKKSDAGWYTLSAKNEAG--IVSCTARLDI 988
Score = 50.8 bits (116), Expect = 8e-05
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 40/218 (18%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDE-SSRCHLGKEERGVFF 252
AP F LK P FT K+ P P + W++D + + + + C + +E G
Sbjct: 669 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 728
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ-SVTSCFLKLIIP----------RHYKKPRFLEN-- 299
L I++ D + +A N G+ S + + +P H + R E
Sbjct: 729 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDK 788
Query: 300 ------------LQA---ILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
LQA +++ EG + L+CKV G+P P L W +G+ + P H+++
Sbjct: 789 EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLV 848
Query: 344 GQDGTCSL----------GTYTCEASNCMGVAASSASL 371
+ G SL GTY C A+N G + S L
Sbjct: 849 RETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLEL 886
Score = 48.0 bits (109), Expect = 5e-04
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIH-RIISGQDGTCSL 351
P F + L+ EG+ V CK++G+P P + W+KDG+++ + H ++ DGTCSL
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G YT A+N G + S L+
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLM 760
Score = 41.5 bits (93), Expect = 0.046
Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 18/96 (18%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------- 345
P F + LQ + + EG V EC+V G P P ++WY++G ++ RI+ +
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASL 371
+ C+L G +TC ASN G +S A L
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQL 255
Score = 38.7 bits (86), Expect = 0.33
Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDG 134
P F + LQ + EG LV FEC+V G P+P + W+++G
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREG 197
>AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein.
Length = 1320
Score = 108 bits (259), Expect = 4e-22
Identities = 97/307 (31%), Positives = 135/307 (43%), Gaps = 44/307 (14%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVY-----QLTGTNSL----------G 152
+TE V+F CK+VG P P + WFKDG+++ + + + GT SL G
Sbjct: 956 VTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDG 1015
Query: 153 SYCCIAKNCMGQASSSAELTVEDI---------------QNQLNEEEKLQLFSKNQAPKF 197
+Y +A N G+ S S L V+ + ++++ E +K L + P F
Sbjct: 1016 NYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHF 1075
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
+ + A R KV+ P P L W + QPV + + E GV L I
Sbjct: 1076 LQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDP 1135
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKV 316
L D +KC+A N GQ+ S L ++ K P LE LQ EG V LEC+V
Sbjct: 1136 LTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV 1195
Query: 317 IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT---CSL---------GTYTCEASNCMGV 364
IG+P PV W KD E + P RI QD T C L G YT A N G+
Sbjct: 1196 IGMPPPVFYWKKDNETI-PCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGI 1254
Query: 365 AASSASL 371
+ +A L
Sbjct: 1255 VSCTARL 1261
Score = 59.3 bits (137), Expect = 2e-07
Identities = 58/211 (27%), Positives = 94/211 (44%), Gaps = 31/211 (14%)
Query: 93 KNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
+ + +P F++ ++ EG L +CKV G P P L+W +GQ + P +++ TG
Sbjct: 1068 ERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETG 1127
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKF 197
+SL G+Y CIA N GQ S S EL+V + +E K +AP
Sbjct: 1128 VHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV------VAKEVK-------KAPVI 1174
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQ 256
+ L++ P R +V P P W +D++ + R + ++ G L IQ
Sbjct: 1175 LEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQ 1234
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + A N+ G + SC +L I
Sbjct: 1235 PAKKSDAGWYTLSAKNEAG--IVSCTARLDI 1263
Score = 54.0 bits (124), Expect = 8e-06
Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQDGTCSL 351
PRF + L++ EG V L+C V+G+P P ++WY +G+EL+ DIH + +G + ++
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 352 --------GTYTCEASNCMGVAASSASL 371
G Y+C ASN G ++SA +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEI 356
Score = 51.6 bits (118), Expect = 4e-05
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 15/126 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG 147
PRF + L++ EG V +C VVG P P + W+ +G+EL + G+++ LT
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNE-EEKLQLFSKNQAPKFVHGLK 202
+ G Y C A N G S+SAE+ +E + + +E + + ++ Q P V
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 388
Query: 203 SVEAKI 208
+ A I
Sbjct: 389 TTSAVI 394
Score = 50.8 bits (116), Expect = 8e-05
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 40/218 (18%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDE-SSRCHLGKEERGVFF 252
AP F LK P FT K+ P P + W++D + + + + C + +E G
Sbjct: 944 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 1003
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ-SVTSCFLKLIIP----------RHYKKPRFLEN-- 299
L I++ D + +A N G+ S + + +P H + R E
Sbjct: 1004 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDK 1063
Query: 300 ------------LQA---ILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
LQA +++ EG + L+CKV G+P P L W +G+ + P H+++
Sbjct: 1064 EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLV 1123
Query: 344 GQDGTCSL----------GTYTCEASNCMGVAASSASL 371
+ G SL GTY C A+N G + S L
Sbjct: 1124 RETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLEL 1161
Score = 48.0 bits (109), Expect = 5e-04
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIH-RIISGQDGTCSL 351
P F + L+ EG+ V CK++G+P P + W+KDG+++ + H ++ DGTCSL
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G YT A+N G + S L+
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLM 1035
Score = 41.5 bits (93), Expect = 0.046
Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 18/96 (18%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------- 345
P F + LQ + + EG V EC+V G P P ++WY++G ++ RI+ +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASL 371
+ C+L G +TC ASN G +S A L
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQL 530
Score = 38.7 bits (86), Expect = 0.33
Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDG 134
P F + LQ + EG LV FEC+V G P+P + W+++G
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREG 472
>AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein
protein.
Length = 1391
Score = 107 bits (257), Expect = 6e-22
Identities = 96/307 (31%), Positives = 135/307 (43%), Gaps = 44/307 (14%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL----------KPGDV-----YQLTGTNSLG 152
+TE V+F CK+VG P P + WFKDG+++ + GD + T ++ G
Sbjct: 1027 VTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSLHIESTTSDDDG 1086
Query: 153 SYCCIAKNCMGQASSSAELTVEDI---------------QNQLNEEEKLQLFSKNQAPKF 197
+Y +A N G+ S S L V+ + ++++ E +K L + P F
Sbjct: 1087 NYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHF 1146
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
+ + A R KV+ P P L W + QPV + + E GV L I
Sbjct: 1147 LQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDP 1206
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKV 316
L D +KC+A N GQ+ S L ++ K P LE LQ EG V LEC+V
Sbjct: 1207 LTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV 1266
Query: 317 IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT---CSL---------GTYTCEASNCMGV 364
IG+P PV W KD E + P RI QD T C L G YT A N G+
Sbjct: 1267 IGMPPPVFYWKKDNETI-PCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGI 1325
Query: 365 AASSASL 371
+ +A L
Sbjct: 1326 VSCTARL 1332
Score = 59.3 bits (137), Expect = 2e-07
Identities = 58/211 (27%), Positives = 94/211 (44%), Gaps = 31/211 (14%)
Query: 93 KNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
+ + +P F++ ++ EG L +CKV G P P L+W +GQ + P +++ TG
Sbjct: 1139 ERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETG 1198
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKF 197
+SL G+Y CIA N GQ S S EL+V + +E K +AP
Sbjct: 1199 VHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV------VAKEVK-------KAPVI 1245
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQ 256
+ L++ P R +V P P W +D++ + R + ++ G L IQ
Sbjct: 1246 LEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQ 1305
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + A N+ G + SC +L I
Sbjct: 1306 PAKKSDAGWYTLSAKNEAG--IVSCTARLDI 1334
Score = 54.0 bits (124), Expect = 8e-06
Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQDGTCSL 351
PRF + L++ EG V L+C V+G+P P ++WY +G+EL+ DIH + +G + ++
Sbjct: 340 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 399
Query: 352 --------GTYTCEASNCMGVAASSASL 371
G Y+C ASN G ++SA +
Sbjct: 400 AEAFEEDTGRYSCFASNIYGTDSTSAEI 427
Score = 52.4 bits (120), Expect = 2e-05
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 40/218 (18%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDE-SSRCHLGKEERGVFF 252
AP F LK P FT K+ P P + W++D + + + + RC + +E G
Sbjct: 1015 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCS 1074
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ-SVTSCFLKLIIP----------RHYKKPRFLEN-- 299
L I++ D + +A N G+ S + + +P H + R E
Sbjct: 1075 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDK 1134
Query: 300 ------------LQA---ILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
LQA +++ EG + L+CKV G+P P L W +G+ + P H+++
Sbjct: 1135 EPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLV 1194
Query: 344 GQDGTCSL----------GTYTCEASNCMGVAASSASL 371
+ G SL GTY C A+N G + S L
Sbjct: 1195 RETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLEL 1232
Score = 51.6 bits (118), Expect = 4e-05
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 15/126 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG 147
PRF + L++ EG V +C VVG P P + W+ +G+EL + G+++ LT
Sbjct: 340 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 399
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNE-EEKLQLFSKNQAPKFVHGLK 202
+ G Y C A N G S+SAE+ +E + + +E + + ++ Q P V
Sbjct: 400 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 459
Query: 203 SVEAKI 208
+ A I
Sbjct: 460 TTSAVI 465
Score = 46.4 bits (105), Expect = 0.002
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRIISGQDGTCSL 351
P F + L+ EG+ V CK++G+P P + W+KDG+++ K + ++ DGTCSL
Sbjct: 1016 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSL 1075
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G YT A+N G + S L+
Sbjct: 1076 HIESTTSDDDGNYTIMAANPQGRISCSGHLM 1106
Score = 41.5 bits (93), Expect = 0.046
Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 18/96 (18%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------- 345
P F + LQ + + EG V EC+V G P P ++WY++G ++ RI+ +
Sbjct: 506 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 565
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASL 371
+ C+L G +TC ASN G +S A L
Sbjct: 566 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQL 601
Score = 38.7 bits (86), Expect = 0.33
Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDG 134
P F + LQ + EG LV FEC+V G P+P + W+++G
Sbjct: 506 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREG 543
>AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein
protein.
Length = 1045
Score = 107 bits (257), Expect = 6e-22
Identities = 97/307 (31%), Positives = 135/307 (43%), Gaps = 44/307 (14%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVY-----QLTGTNSL----------G 152
+TE V+F CK+VG P P + WFKDG+++ + + + GT SL G
Sbjct: 681 VTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDG 740
Query: 153 SYCCIAKNCMGQASSSAELTVEDI---------------QNQLNEEEKLQLFSKNQAPKF 197
+Y +A N G+ S S L V+ + ++++ E +K L + P F
Sbjct: 741 NYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHF 800
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
+ + A R KV+ P P L W + QPV + + E GV L I
Sbjct: 801 LQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDP 860
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKV 316
L D +KC+A N GQ+ S L ++ K P LE LQ EG V LEC+V
Sbjct: 861 LTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRV 920
Query: 317 IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT---CSL---------GTYTCEASNCMGV 364
IG+P PV W KD E + P RI QD T C L G YT A N G+
Sbjct: 921 IGMPPPVFYWKKDNETI-PCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGI 979
Query: 365 AASSASL 371
+ +A L
Sbjct: 980 VSCTARL 986
Score = 60.1 bits (139), Expect = 1e-07
Identities = 58/211 (27%), Positives = 94/211 (44%), Gaps = 31/211 (14%)
Query: 93 KNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
+ + +P F++ ++ EG L +CKV G P P L+W +GQ + P +++ TG
Sbjct: 793 ERFFRPHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETG 852
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKF 197
+SL G+Y CIA N GQ S S EL+V + +E K +AP
Sbjct: 853 VHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV------VAKEVK-------KAPVI 899
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQ 256
+ L++ P R +V P P W +D++ + R + ++ G L IQ
Sbjct: 900 LEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQ 959
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + A N+ G + SC +L I
Sbjct: 960 PAKKSDAGWYTLSAKNEAG--IVSCTARLDI 988
Score = 48.0 bits (109), Expect = 5e-04
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIH-RIISGQDGTCSL 351
P F + L+ EG+ V CK++G+P P + W+KDG+++ + H ++ DGTCSL
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G YT A+N G + S L+
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLM 760
Score = 41.5 bits (93), Expect = 0.046
Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 18/96 (18%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------- 345
P F + LQ + + EG V EC+V G P P ++WY++G ++ RI+ +
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASL 371
+ C+L G +TC ASN G +S A L
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQL 255
Score = 38.7 bits (86), Expect = 0.33
Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDG 134
P F + LQ + EG LV FEC+V G P+P + W+++G
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREG 197
Score = 38.7 bits (86), Expect = 0.33
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDE-SSRCHLGKEERGVFF 252
AP F LK P FT K+ P P + W++D + + + + C + +E G
Sbjct: 669 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 728
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ 276
L I++ D + +A N G+
Sbjct: 729 LHIESTTSDDDGNYTIMAANPQGR 752
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 105 bits (252), Expect = 3e-21
Identities = 91/308 (29%), Positives = 142/308 (46%), Gaps = 53/308 (17%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP 139
S K+I + H P KP ++ L E G +F+C V G ++W KD +E++P
Sbjct: 3865 SAKLILSEHEVPPFFDLKP---VSVDLALGESG--TFKCHVTGTAPIKITWAKDNREIRP 3919
Query: 140 GDVYQLT-------------GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKL 186
G Y++T G G Y C A N G+ S SA+L V++
Sbjct: 3920 GGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE----------- 3968
Query: 187 QLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGK 245
P+F+ L+ S K DE R+ K+ PE +LWY+D+ + ESS+ +
Sbjct: 3969 -------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF 4021
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHY-KKPRFLENLQAIL 304
+ V L++ L D ++ C A N G + +S LK+ P + KKP +E L+
Sbjct: 4022 VD-SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKG-- 4078
Query: 305 SDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGT---------CSLGTYT 355
V+LEC++ G P + WYKD EL+ G ++I+S T +G Y
Sbjct: 4079 ---ADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQ 4135
Query: 356 CEASNCMG 363
C+A+N +G
Sbjct: 4136 CKATNDVG 4143
Score = 102 bits (245), Expect = 2e-20
Identities = 82/301 (27%), Positives = 138/301 (45%), Gaps = 32/301 (10%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P + LQ +T EG + F+C+V G V SW+ +++KP D YQL
Sbjct: 10 PAIITPLQDTVTSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFEDTYQLEI 68
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNE--EEKLQLFSKNQAPKFVHGL 201
+ G+Y +A N +GQ SS+A L++E ++ L+E E+++++ K AP +
Sbjct: 69 AEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMK-AAPVIKRKI 127
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
+ +E + +FT ++ P W++ + + ES +C + + + + L+I + +
Sbjct: 128 EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVV 186
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVP 320
D E+ C A N++G SC L + Y P FL +++ + G A C V G P
Sbjct: 187 DCGEYTCKASNEYGS--VSCTATLTVTEAY-PPTFLSRPKSLTTFVGKAAKFICTVTGTP 243
Query: 321 QPVLKWYKDGEELKPGDIHRIISGQDGTC---------SLGTYTCEASNCMGVAASSASL 371
W KDG L P RI ++ G Y+C+ASN G A L
Sbjct: 244 VIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAEL 303
Query: 372 L 372
+
Sbjct: 304 I 304
Score = 88.6 bits (210), Expect = 3e-16
Identities = 68/285 (23%), Positives = 126/285 (44%), Gaps = 20/285 (7%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + +V G+ ++F + G P + WFK +EL PG+ + SL +
Sbjct: 3499 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNI----SLEDFVT 3554
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+ Q S + + + + LF K A FV L + P
Sbjct: 3555 ELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPA-TFVKRLADFSVETGSPIVLEA 3613
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
P S+ W +D+ + +S RC + E+ L+I D A++ C+ N+ GQ
Sbjct: 3614 TYTGTPPISVSWIKDEYLISQSERCSITMTEKST-ILEILESTIEDYAQYSCLIENEAGQ 3672
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
+ + ++ P ++ +P LE+++A++ + L+CKV G P+ + WYK+ +L+
Sbjct: 3673 DICEALVSVLEPPYFIEP--LEHVEAVIGE--PATLQCKVDGTPEIRISWYKEHTKLRSA 3728
Query: 337 DIHR---------IISGQDGTCSLGTYTCEASNCMGVAASSASLL 372
++ ++ + +G Y+C+A N +G ASSA L+
Sbjct: 3729 PAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLV 3773
Score = 84.2 bits (199), Expect = 7e-15
Identities = 77/278 (27%), Positives = 120/278 (43%), Gaps = 26/278 (9%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASS 167
+T+ + + K G WFKDGQEL G Y+++ T+++ I K +
Sbjct: 1255 VTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVS----ILKIISTEKKD 1310
Query: 168 SAELTVEDIQNQLNE---EEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEP 224
S E T E +QN + + ++ + P F LK +++ VA
Sbjct: 1311 SGEYTFE-VQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPI 1369
Query: 225 SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
S+ W++DDQ + S + + FL+I LE D + C A N G + S L
Sbjct: 1370 SIQWFKDDQEISASEKYKFSFHD-NTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLT 1428
Query: 285 LIIPRHYKKPRFLENLQA-ILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
+ P P F+E Q+ ++ V L+ V G +KW+KD +EL G R +
Sbjct: 1429 VKEP-----PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSG-AARSVW 1482
Query: 344 GQDGTCSL----------GTYTCEASNCMGVAASSASL 371
D + SL GTY C+ SN +G A S A+L
Sbjct: 1483 KDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATL 1520
Score = 83.8 bits (198), Expect = 9e-15
Identities = 73/287 (25%), Positives = 126/287 (43%), Gaps = 23/287 (8%)
Query: 99 RFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
+ +E ++V +TE+ ++ EC V G P + W KDG+++ P + ++ N++ S+
Sbjct: 1807 QIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASF--R 1864
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
++ M Q S VE+ + + L++ +N P F L ++ + K
Sbjct: 1865 IQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECK 1924
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ S W++D + + S++ L ER V L++ LE D A + C N G
Sbjct: 1925 VSGSLPISAQWFKDGKEISTSAKYRLVCHERSV-SLEVNNLELEDTANYTCKVSNVAGDD 1983
Query: 278 VTSCFLKLIIPRHY-KKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
S L + P + KP QAI + V + + G P +KW+KD EL G
Sbjct: 1984 ACSGILTVKEPPSFLVKP---GRQQAI--PDSTVEFKAILKGTPPFKIKWFKDDVELVSG 2038
Query: 337 DIHRIISGQDGTCSL-----------GTYTCEASNCMGVAASSASLL 372
+ G +G+ S G YTC +N +G + + LL
Sbjct: 2039 P--KCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLL 2083
Score = 81.0 bits (191), Expect = 6e-14
Identities = 75/284 (26%), Positives = 116/284 (40%), Gaps = 19/284 (6%)
Query: 100 FMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
F++ L E G + E G P +SW KD + + +T T +
Sbjct: 3594 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 3653
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
A S I+N+ ++ L S + P F+ L+ VEA I EP KV
Sbjct: 3654 STIEDYAQYSCL-----IENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKV 3708
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
PE + WY++ + S+ + + + V L I ++ D E+ C A N G
Sbjct: 3709 DGTPEIRISWYKEHTKL-RSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVA 3767
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDG------E 331
+S L+I P F L+ + G V EC++ G + WYKDG
Sbjct: 3768 SSAV--LVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDA 3825
Query: 332 ELKPGDIHRIIS---GQDGTCSLGTYTCEASNCMGVAASSASLL 372
L+ +H + + Q +G Y C ASN +G A+SSA L+
Sbjct: 3826 NLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLI 3869
Score = 79.0 bits (186), Expect = 2e-13
Identities = 66/260 (25%), Positives = 110/260 (42%), Gaps = 18/260 (6%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC V G +SW KD +E++ G YQ++ + ++ + K G + V +
Sbjct: 4837 FECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN-SAHLTVLKVDKGDSGQYTCYAVNE 4895
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGL-KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + +L + + P F L ++VE F+ +VA ++ WY+++
Sbjct: 4896 VGKD-SCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIE 4954
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP 294
+ +S C + + L ++ D + C ND G ++ C ++I K P
Sbjct: 4955 IQPTSNCEI-TFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSAL--CTSSIVIKEPKKPP 5011
Query: 295 RFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
F ++L + EG V L C V G ++W K G E+KP D S GT L
Sbjct: 5012 VFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSD-RCSFSFASGTAVLEL 5070
Query: 352 --------GTYTCEASNCMG 363
G Y C+ASN G
Sbjct: 5071 RDVAKADSGDYVCKASNVAG 5090
Score = 78.2 bits (184), Expect = 4e-13
Identities = 56/240 (23%), Positives = 112/240 (46%), Gaps = 13/240 (5%)
Query: 98 PRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F+ L+ V + + V EC+V G P ++W K+ +E++ Y LT S+ +
Sbjct: 1620 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSV--FNL 1677
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
C + + V + + ++ L + P F+ +++ + F
Sbjct: 1678 HITKCDPSDTGEYQCIVSNEGGSCSCSTRVAL---KEPPSFIKKIENTTTVLKSSATFQS 1734
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
VA P S+ W +DDQ +DE ++ + V L I++++ + C A N+ G
Sbjct: 1735 TVAGSPPISITWLKDDQILDEDDNVYISFVD-SVATLQIRSVDNGHSGRYTCQAKNESG- 1792
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
V C+ L++ + + +E +++ ++++ + LEC V G P+ +KW KDG+++ P
Sbjct: 1793 -VERCYAFLLV---QEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVP 1848
Score = 78.2 bits (184), Expect = 4e-13
Identities = 70/288 (24%), Positives = 124/288 (43%), Gaps = 22/288 (7%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS--Y 154
P F+ L+ + G VS +C+V G P +SW+K +L+P Y+ TN++ + +
Sbjct: 2744 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVF 2803
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ N G+ + AE ++ + + ++ + P F LK +E + P
Sbjct: 2804 NKVNINDSGEYTCKAENSI----GTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTL 2859
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
T ++ + WYRD + + + V L I + ++ C A N
Sbjct: 2860 TCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVD-NVATLKILQTDLSHSGQYSCSASNPL 2918
Query: 275 GQSVTSCFLKLIIPRHYKKPRF-LENLQA-ILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G + +S L P+ K P F ++ + +++ E A + EC V G + W KD +E
Sbjct: 2919 GTASSSARLTAREPK--KSPFFDIKPVSIDVIAGESA-DFECHVTGAQPMRITWSKDNKE 2975
Query: 333 LKPGDIHRIISGQD---------GTCSLGTYTCEASNCMGVAASSASL 371
++PG + I + G G YTC+A+N +G SA L
Sbjct: 2976 IRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 3023
Score = 77.4 bits (182), Expect = 8e-13
Identities = 73/286 (25%), Positives = 120/286 (41%), Gaps = 27/286 (9%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
R +E L+ L L F C++ P WFK G+E+ D + + + S +
Sbjct: 125 RKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR 182
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRFTI 216
Q E T + N+ + +A P F+ KS+ + + +F
Sbjct: 183 T----QVVDCGEYTCK-ASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFIC 237
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
V P +W +D + S + E L++ L D+ + C A N FG
Sbjct: 238 TVTGTPVIETIWQKDGAALSPSPNWRISDAENK-HILELSNLTIQDRGVYSCKASNKFGA 296
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSD-EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ C +LII KP F++ L+ + S V+LEC+V + + W KDG++L P
Sbjct: 297 DI--CQAELII---IDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPP 351
Query: 336 GDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
G ++I +D +L GTY C ASN G ++ SA++
Sbjct: 352 GKDYKICF-EDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATV 396
Score = 76.2 bits (179), Expect = 2e-12
Identities = 72/297 (24%), Positives = 124/297 (41%), Gaps = 23/297 (7%)
Query: 87 SHPTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
S T K P F + + T +G V EC++ G P +SW+KD +EL+ G Y++
Sbjct: 4053 SSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI 4112
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
N L S + + + T N + + + + P+FV L +
Sbjct: 4113 MSENFLTSIHILNVDAADIGEYQCKAT-----NDVGSDTCVGSIALKAPPRFVKKLSDIS 4167
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRD-DQPVDESSRCHLGKEERGVFFLDIQALEFLDQA 264
+ + + + S++W++D + V ES + E + L +E +
Sbjct: 4168 TVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSE-NIATLQFSRVEPANAG 4226
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRH-YKKPRFLENLQAILSDEGAVNLECKVIGVPQPV 323
++ C ND G L ++ P +KP E+++ D LEC V G P+
Sbjct: 4227 KYTCQIKNDAGMQECFATLSVLEPATIVEKP---ESIKVTTGD--TCTLECTVAGTPELS 4281
Query: 324 LKWYKDGEELKPGDIHRI-----ISG----QDGTCSLGTYTCEASNCMGVAASSASL 371
KW+KDG+EL + ++I +SG G Y+ E N +G + +ASL
Sbjct: 4282 TKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASL 4338
Score = 75.8 bits (178), Expect = 2e-12
Identities = 76/299 (25%), Positives = 129/299 (43%), Gaps = 44/299 (14%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F++ L+ V G S +C++ G P +SW+K +L+P Y++ N++
Sbjct: 4626 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVF 4685
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G Y C A+N +G+ S+S LTV +E+KL P F L+
Sbjct: 4686 NQVDINDSGEYICKAENSVGEVSASTFLTV--------QEQKL-------PPSFSRQLRD 4730
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
V+ + P F ++ S+ WY+D +P+ +S + L+I +
Sbjct: 4731 VQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLD-NTATLNIFKTDRSLA 4789
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQP 322
++ C A N G + +S +LI+ P F L + + G + + EC V G
Sbjct: 4790 GQYSCTATNPIGSASSSA--RLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPI 4847
Query: 323 VLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
+ W KD E++ G ++ IS + + L G YTC A N +G + +A L
Sbjct: 4848 KVSWAKDSREIRSGGKYQ-ISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL 4905
Score = 75.4 bits (177), Expect = 3e-12
Identities = 82/308 (26%), Positives = 125/308 (40%), Gaps = 43/308 (13%)
Query: 90 TVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQ---L 145
TV + P F L+ V GL V F+C + G +SW+KDG+ LK Q L
Sbjct: 4714 TVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFL 4773
Query: 146 TGTNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
T +L G Y C A N +G ASSSA L + + +N P
Sbjct: 4774 DNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNP---------------P 4818
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDI 255
F L V+A + E F V + W +D + + + + E L +
Sbjct: 4819 FFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAH-LTV 4877
Query: 256 QALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSD-EG-AVNLE 313
++ D ++ C A N+ G+ SC +L I P F + L + + EG + LE
Sbjct: 4878 LKVDKGDSGQYTCYAVNEVGKD--SCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLE 4935
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD---------GTCSLGTYTCEASNCMGV 364
+V G + WYK+ E++P I + G G YTC+ SN G
Sbjct: 4936 GRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGS 4995
Query: 365 AASSASLL 372
A ++S++
Sbjct: 4996 ALCTSSIV 5003
Score = 74.9 bits (176), Expect = 4e-12
Identities = 64/270 (23%), Positives = 115/270 (42%), Gaps = 22/270 (8%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
+ ECKV G WFKDG+E+ Y+L S + N + + +A T
Sbjct: 1919 IHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVS---LEVNNL-ELEDTANYTC 1974
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+ + N ++ + + + P F+ +A D F + P + W++DD
Sbjct: 1975 K-VSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDV 2033
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ +C +G E FL++ +++ ++ C ND G SC L++ +
Sbjct: 2034 ELVSGPKCFIGLEG-STSFLNLYSVDASKTGQYTCHVTNDVGSD--SCTTMLLVT---EP 2087
Query: 294 PRFLENLQA--ILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHR---------II 342
P+F++ L+A I+ + LECK+ G P+ + W+++ EL D +R I
Sbjct: 2088 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 2147
Query: 343 SGQDGTCSLGTYTCEASNCMGVAASSASLL 372
T G + CEA N G + S ++
Sbjct: 2148 MNNLSTEDSGDFICEAQNPAGSTSCSTKVI 2177
Score = 73.7 bits (173), Expect = 9e-12
Identities = 85/302 (28%), Positives = 127/302 (42%), Gaps = 52/302 (17%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----------- 145
P F L+ V G V+FEC++ G +SW+KDG LK Q
Sbjct: 3781 PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQI 3840
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK- 202
T + +G Y C A N +G ASSSA+L + S+++ P F LK
Sbjct: 3841 LQTDQSHIGQYNCSASNPLGTASSSAKL----------------ILSEHEVPPFFD-LKP 3883
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
SV+ + E F V + W +D++ + + E L + +
Sbjct: 3884 VSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTAT-LTVLKVGKG 3942
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQA--ILSDEGAVNLECKVIGV 319
D ++ C A N G+ SC +L + + PRF++ L+ I+ + ECK+ G
Sbjct: 3943 DAGQYTCYASNIAGKD--SCSAQLGVQ---EPPRFIKKLEPSRIVKQDEFTRYECKIGGS 3997
Query: 320 PQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSA 369
P+ + WYKD E++ R+ S D L G YTCEA N G A+SS
Sbjct: 3998 PEIKVLWYKDETEIQESSKFRM-SFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 4056
Query: 370 SL 371
SL
Sbjct: 4057 SL 4058
Score = 72.1 bits (169), Expect = 3e-11
Identities = 76/300 (25%), Positives = 123/300 (41%), Gaps = 51/300 (17%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVY------------- 143
P F + L+ + + +G + EC V G + WFKD QE+ + Y
Sbjct: 1340 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 1399
Query: 144 -QLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
QL GT+S G+Y C A N G S LTV++ P FV +
Sbjct: 1400 SQLEGTDS-GTYTCSATNKAGHNQCSGHLTVKE------------------PPYFVEKPQ 1440
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
S + + + V ++ W++D++ + + + K++ L++ A + D
Sbjct: 1441 SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTS-LELFAAKATD 1499
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHY-KKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
+ C ND G + + L + P + KKP + +L + + EC++ G P+
Sbjct: 1500 SGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPV----LVLRNGQSTTFECQITGTPK 1555
Query: 322 PVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
+ WY DG E+ H IS DG + GTY CEA N G A+ S L
Sbjct: 1556 IRVSWYLDGNEITAIQKHG-ISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIEL 1614
Score = 72.1 bits (169), Expect = 3e-11
Identities = 69/270 (25%), Positives = 111/270 (41%), Gaps = 23/270 (8%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V ECKV G P +SWF +G E+ G YQ T T++ C + N M + S S + T
Sbjct: 4364 VVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT---CALTVN-MLEESDSGDYTC 4419
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +E + + P FV ++ FT V P S+ W++
Sbjct: 4420 -IATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSS 4478
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ RC++ E+ V L++ ++ E+ C+ N+ G++ SC L I K
Sbjct: 4479 ELVPGDRCNVSLED-SVAELELFDVDTSQSGEYTCIVSNEAGKA--SCTTHLYI----KA 4531
Query: 294 P-RFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC-- 349
P +F++ L ++G + LE G P + W K+G + P I + +
Sbjct: 4532 PAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILE 4591
Query: 350 -------SLGTYTCEASNCMGVAASSASLL 372
G Y C N G + SA +L
Sbjct: 4592 IPSSTVEDAGQYNCYIENASGKDSCSAQIL 4621
Score = 71.3 bits (167), Expect = 5e-11
Identities = 80/300 (26%), Positives = 124/300 (41%), Gaps = 49/300 (16%)
Query: 98 PRFMENLQAVLTEEG--LVSFECKVVGFPTPVLSWFKDGQEL----KPG-------DVYQ 144
P+F++ VL +FEC++ G P +SW+ DG E+ K G +Q
Sbjct: 1526 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQ 1585
Query: 145 LTGTN--SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
++G + G+Y C A+N G AS S EL V++ P F+ LK
Sbjct: 1586 ISGARVENSGTYVCEARNDAGTASCSIELKVKE------------------PPTFIRELK 1627
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
VE +V P + W ++++ + S + L + VF L I + D
Sbjct: 1628 PVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL-TDRVSVFNLHITKCDPSD 1686
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQP 322
E++C+ N+ G S + L P + K +EN +L + + + V G P
Sbjct: 1687 TGEYQCIVSNEGGSCSCSTRVALKEPPSFIKK--IENTTTVL--KSSATFQSTVAGSPPI 1742
Query: 323 VLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ W KD + L D + IS D +L G YTC+A N GV A LL
Sbjct: 1743 SITWLKDDQILDEDD-NVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLL 1801
Score = 70.1 bits (164), Expect = 1e-10
Identities = 75/303 (24%), Positives = 131/303 (43%), Gaps = 53/303 (17%)
Query: 97 KPRFMENLQAVLTE-EGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
KP F++ L+ V + V EC+V ++W KDGQ+L PG Y++ + +
Sbjct: 308 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE 367
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G+Y C A N G +S SA +TV + + F K P ++
Sbjct: 368 IPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS----------FVKKVDPSYL---- 413
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS--RCHLGKEERGVFFLDIQALEF 260
E R K+ P + W+++++ + ES+ R + E LDI ++
Sbjct: 414 ---MLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEA---ILDITDVKV 467
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQA--ILSDEGAVNLECKVIG 318
D + C A ND G SC +++I + P F++ L+ I+ A+ L+C+V G
Sbjct: 468 EDSGSYSCEAVNDVGSD--SCSTEIVIK---EPPSFIKTLEPADIVRGTNAL-LQCEVSG 521
Query: 319 VPQPVLKWYKDGEELKPGDIHRIISGQDGTC---------SLGTYTCEASNCMGVAASSA 369
+ W+KD ++++ +R+ S + C +G Y C +N +G A
Sbjct: 522 TGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMA 581
Query: 370 SLL 372
+ L
Sbjct: 582 THL 584
Score = 68.9 bits (161), Expect = 3e-10
Identities = 67/268 (25%), Positives = 108/268 (40%), Gaps = 20/268 (7%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ EC V G P WFKDG+EL + +T N + S + S E V+
Sbjct: 3328 ALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFE--VK 3385
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + N + + + P F+ LK V A + +V+ S+ W++D
Sbjct: 3386 NSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNE 3445
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK- 293
+ +C E V L++ LE D + CVA N G S L + P +++
Sbjct: 3446 IVSGPKCQSSFSE-NVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT 3504
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
P +E L + ++ + G P +KW+K EL PG+ IS +D L
Sbjct: 3505 PDSVEVLPGM-----SLTFTSVIRGTPPFKVKWFKGSRELVPGESCN-ISLEDFVTELEL 3558
Query: 352 --------GTYTCEASNCMGVAASSASL 371
G Y+C +N G A+ + L
Sbjct: 3559 FEVQPLESGDYSCLVTNDAGSASCTTHL 3586
Score = 67.7 bits (158), Expect = 6e-10
Identities = 76/279 (27%), Positives = 120/279 (43%), Gaps = 40/279 (14%)
Query: 98 PRFMENLQA--VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
P+F++ L+A V + + ECK+ G P +SWF++ EL Y ++ NS+
Sbjct: 3029 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT 3088
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G Y C A N +G AS S LTV+ +F++ +P V LK
Sbjct: 3089 INEASAEDSGDYICEAHNGVGDASCSTALTVK----------APPVFTQKPSP--VGALK 3136
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
+ + +++ P ++W +D + V S + + + L I LE D
Sbjct: 3137 GSDVILQ------CEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTN-LHILNLEASD 3189
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQP 322
E+ C A N+ G SC +K P + K L + ++ D AV L V G
Sbjct: 3190 VGEYHCKATNEVGSDTCSCSVKFKEPPRFVKK--LSDTSTLIGD--AVELRAIVEGFQPI 3245
Query: 323 VLKWYKD-GEELKPGDIHRIISGQDGTCSLGTYTCEASN 360
+ W KD GE ++ + R IS D +L + EASN
Sbjct: 3246 SVVWLKDRGEVIRESENTR-ISFIDNIATLQLGSPEASN 3283
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/234 (26%), Positives = 101/234 (43%), Gaps = 37/234 (15%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C+A+N G +S EL V++ K + + ++ +P
Sbjct: 657 GKYTCLAENEAGSQTSVGELIVKE------------------PAKIIERAELIQVTAGDP 698
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
VA PE WY+D +P+ S + + + V L + E D ++
Sbjct: 699 ATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNN-VAQLKFYSAELHDSGQYTFEIS 757
Query: 272 NDFGQS---VTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK 328
N+ G S T L I + KP L N+ ++++ G L+CK+ G + W+K
Sbjct: 758 NEVGSSSCETTFTVLDRDIAPFFTKP--LRNVDSVVN--GTCRLDCKIAGSLPMRVSWFK 813
Query: 329 DGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
DG+E+ D +R I+ +GT SL G +TC A+N +G SS +L+
Sbjct: 814 DGKEIAASDRYR-IAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALI 866
Score = 64.9 bits (151), Expect = 4e-09
Identities = 68/283 (24%), Positives = 112/283 (39%), Gaps = 19/283 (6%)
Query: 100 FMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
F++ L E G + E G ++W KDG + + + T CI
Sbjct: 2653 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKT----CIL 2708
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ + + + E I+N+ + L S + P FV L+ +EA + + +V
Sbjct: 2709 EILNSTKRDAGQYSCE-IENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQV 2767
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
A PE ++ WY+ D + + + V L + D E+ C A N G +
Sbjct: 2768 AGTPEITVSWYKGDTKLRPTPE-YRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTAS 2826
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDG------E 331
+ + I P F L+ I G V L C++ G + WY+DG E
Sbjct: 2827 SKTVFR--IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHE 2884
Query: 332 ELKPGDIHRIIS---GQDGTCSLGTYTCEASNCMGVAASSASL 371
L+ + + + Q G Y+C ASN +G A+SSA L
Sbjct: 2885 NLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 2927
Score = 63.7 bits (148), Expect = 1e-08
Identities = 77/295 (26%), Positives = 125/295 (42%), Gaps = 56/295 (18%)
Query: 95 YRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL 151
+ KP + N+ +V+ G +CK+ G +SWFKDG+E+ D Y++ GT SL
Sbjct: 780 FTKP--LRNVDSVVN--GTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 835
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL 201
G++ C A N +G SS L V++ + + + SK+ P L
Sbjct: 836 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPG-----SKDVLPGSAVCL 890
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
KS T + + P ++ W++ ++ + C++ KE L++ ++
Sbjct: 891 KS-----------TFQGSTPL--TIRWFKGNKELVSGGSCYITKEALESS-LELYLVKTS 936
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR-FLENLQA--ILSDEGAVNLECKVIG 318
D + C N G C L + K+P F+E L+ +L A L CKV G
Sbjct: 937 DSGTYTCKVSNVAGG--VECSANLFV----KEPATFVEKLEPSQLLKKGDATQLACKVTG 990
Query: 319 VPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMG 363
P + W+ + E+K HR +S + T L G Y CEA N G
Sbjct: 991 TPPIKITWFANDREIKESSKHR-MSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 1044
Score = 63.7 bits (148), Expect = 1e-08
Identities = 72/288 (25%), Positives = 119/288 (41%), Gaps = 24/288 (8%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
PRF++ L T G V V GF + W KD G+V + + +
Sbjct: 3216 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDR-----GEVIRESENTRISFIDN 3270
Query: 157 IAKNCMG--QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
IA +G +AS+S + + I+N E + + + + + + + PF
Sbjct: 3271 IATLQLGSPEASNSGKYICQ-IKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFAL 3329
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
V PE S W++D + + S+ H+ + V L I E D+ + N
Sbjct: 3330 ECVVTGTPELSAKWFKDGRELSADSKHHITFINK-VASLKIPCAEMSDKGLYSFEVKNSV 3388
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEEL 333
G+S +C + + + P F+ L+ + + GA V LEC+V G + W++DG E+
Sbjct: 3389 GKS--NCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEI 3446
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
G + S + C+L G YTC A+N G SA L
Sbjct: 3447 VSGPKCQ-SSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 3493
Score = 62.9 bits (146), Expect = 2e-08
Identities = 67/270 (24%), Positives = 112/270 (41%), Gaps = 24/270 (8%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ E V G P W+KDG+ L Y+++ N++ K + S + T E
Sbjct: 700 TLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQL----KFYSAELHDSGQYTFE 755
Query: 175 DIQNQLNE---EEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD 231
I N++ E + ++ AP F L++V++ ++ R K+A + W++D
Sbjct: 756 -ISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKD 814
Query: 232 DQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHY 291
+ + S R + E G L+I ++ D + C A N G +S L + P +
Sbjct: 815 GKEIAASDRYRIAFVE-GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSF 873
Query: 292 -KKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC 349
KP + L AV L+ G ++W+K +EL G I + +
Sbjct: 874 VTKPGSKDVLPG-----SAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSL 928
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
L GTYTC+ SN G SA+L
Sbjct: 929 ELYLVKTSDSGTYTCKVSNVAGGVECSANL 958
Score = 62.1 bits (144), Expect = 3e-08
Identities = 69/289 (23%), Positives = 124/289 (42%), Gaps = 29/289 (10%)
Query: 87 SHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT 146
S VP ++ R ++N VL ++ ECKV G ++WF + ++ G YQ T
Sbjct: 2459 SDRAVPPSFT--RRLKNTGGVLGASCIL--ECKVAGSSPISVAWFHEKTKIVSGAKYQTT 2514
Query: 147 GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
++++ C + N + + V N +E + + + P FV + +E
Sbjct: 2515 FSDNV---CTLQLNSLDSSDMGNYTCVA--ANVAGSDECRAVLTVQEPPSFVKEPEPLEV 2569
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+ FT + P + W+R + + + RC++ E+ V L++ ++ E+
Sbjct: 2570 LPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT-VAELELFNIDISQSGEY 2628
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKP-RFLENLQAILSDEG-AVNLECKVIGVPQPVL 324
CV N+ GQ+ SC +L + K+P FL+ L + G ++ LE G +
Sbjct: 2629 TCVVSNNAGQA--SCTTRLFV----KEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISV 2682
Query: 325 KWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMG 363
W KDG + + I++ + TC L G Y+CE N G
Sbjct: 2683 TWKKDGFNITTSEKCNIVT-TEKTCILEILNSTKRDAGQYSCEIENEAG 2730
Score = 62.1 bits (144), Expect = 3e-08
Identities = 66/286 (23%), Positives = 117/286 (40%), Gaps = 21/286 (7%)
Query: 99 RFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
+F++ L E+G + E G P ++W K+G + P +T T S
Sbjct: 4534 KFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK--SPILE 4591
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
+ + + +E+ + + ++ + + P FV L+ V+ + + +
Sbjct: 4592 IPSSTVEDAGQYNCYIENASGKDSCSAQILIL---EPPYFVKQLEPVKVSVGDSASLQCQ 4648
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+A PE + WY+ D + ++ + V L ++ D E+ C A N G+
Sbjct: 4649 LAGTPEIGVSWYKGDTKLRPTTTYKM-HFRNNVATLVFNQVDINDSGEYICKAENSVGEV 4707
Query: 278 VTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPG 336
S FL + P F L+ + G V +C + G + WYKDG+ LK
Sbjct: 4708 SASTFLT--VQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDS 4765
Query: 337 DIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ S D T +L G Y+C A+N +G A+SSA L+
Sbjct: 4766 PNVQT-SFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLI 4810
Score = 61.7 bits (143), Expect = 4e-08
Identities = 61/252 (24%), Positives = 109/252 (43%), Gaps = 40/252 (15%)
Query: 98 PRFMENLQAV-LTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT--------- 146
P+F++ L+A + + G S ECK+ G P + WF++ EL D Y++T
Sbjct: 2088 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 2147
Query: 147 ----GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
T G + C A+N G S S ++ V++ +FS P V LK
Sbjct: 2148 MNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE----------PPVFS--SFPPIVETLK 2195
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
+ E ++ +++ P ++WY+D + + S + + + + I ++ D
Sbjct: 2196 NAEVSLE------CELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHT-SIHILNVDTSD 2248
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQ 321
E+ C A N+ G C +KL P PRF+ L ++ G L+ + G
Sbjct: 2249 IGEYHCKAQNEVGSDTCVCTVKLKEP-----PRFVSKLNSLTVVAGEPAELQASIEGAQP 2303
Query: 322 PVLKWYKDGEEL 333
++W K+ EE+
Sbjct: 2304 IFVQWLKEKEEV 2315
Score = 61.3 bits (142), Expect = 5e-08
Identities = 64/285 (22%), Positives = 116/285 (40%), Gaps = 25/285 (8%)
Query: 100 FMENLQA--VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
F+E L+ +L + CKV G P ++WF + +E+K ++++ S +
Sbjct: 966 FVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTA---VL 1022
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
+G S E E QN+ + + ++P F K +E + +
Sbjct: 1023 RLTDVG-IEDSGEYMCE-AQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAE 1080
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
VA P + W++D+ + S R + + + L I D E++C N+ G S
Sbjct: 1081 VAGTPPFEITWFKDN-TILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 1139
Query: 278 VTSCFLKLIIPRHYKKPRFLENLQAILS-DEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
+ S + L P P F++ +++ S G + + G + W KD +E+
Sbjct: 1140 ICSARVTLREP-----PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITED 1194
Query: 337 DIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
D R ++ ++ SL G Y C+A N G+ SA L
Sbjct: 1195 DNIR-MTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL 1238
Score = 58.8 bits (136), Expect = 3e-07
Identities = 58/248 (23%), Positives = 104/248 (41%), Gaps = 18/248 (7%)
Query: 84 IHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVY 143
+H S VP ++ R ++++ A+L V EC+V G + WF+DG E+ G
Sbjct: 3397 VHVSDRIVPPSFI--RKLKDVNAILGAS--VVLECRVSGSAPISVGWFQDGNEIVSGPKC 3452
Query: 144 QLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
Q +S C + + S + T N +E + + + P F S
Sbjct: 3453 Q----SSFSENVCTLNLSLLEPSDTGIYTCV-AANVAGSDECSAVLTVQEPPSFEQTPDS 3507
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
VE FT + P + W++ + + C++ E+ V L++ ++ L+
Sbjct: 3508 VEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLED-FVTELELFEVQPLES 3566
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP-RFLENLQAILSDEGA-VNLECKVIGVPQ 321
++ C+ ND G + SC L + K+P F++ L + G+ + LE G P
Sbjct: 3567 GDYSCLVTNDAGSA--SCTTHLFV----KEPATFVKRLADFSVETGSPIVLEATYTGTPP 3620
Query: 322 PVLKWYKD 329
+ W KD
Sbjct: 3621 ISVSWIKD 3628
Score = 58.8 bits (136), Expect = 3e-07
Identities = 66/287 (22%), Positives = 119/287 (41%), Gaps = 22/287 (7%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKD-GQELKPGDVYQLTGTNSLGSYC 155
PRF++ L + T G V + + G + WFKD G+ ++ D ++ + ++ +
Sbjct: 4157 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATL- 4215
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
+ + +++ + T + I+N +E S + V +S++ +
Sbjct: 4216 ---QFSRVEPANAGKYTCQ-IKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLE 4271
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
VA PE S W++D + + ++ + + V L I + D + N G
Sbjct: 4272 CTVAGTPELSTKWFKDGKELTSDNKYKISFFNK-VSGLKIINVAPSDSGVYSFEVQNPVG 4330
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELK 334
+ SC L + P F L+ G+ V +ECKV G P + W+ +G E+
Sbjct: 4331 KD--SCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEIS 4388
Query: 335 PGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
G ++ + D TC+L G YTC A+N G SA L
Sbjct: 4389 SGRKYQ-TTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPL 4434
Score = 58.0 bits (134), Expect = 5e-07
Identities = 63/268 (23%), Positives = 108/268 (40%), Gaps = 24/268 (8%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS EC++ G P + W+KD ++L+ Y++ N S + + S E
Sbjct: 2199 VSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVD----TSDIGEYHC 2254
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD-D 232
+ QN++ + + + P+FV L S+ EP + + W ++ +
Sbjct: 2255 K-AQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKE 2313
Query: 233 QPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK 292
+ + ES + E V L E + ++ C ND G L ++ P
Sbjct: 2314 EVIRESENIRITFVEN-VATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAV-- 2370
Query: 293 KPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL 351
+E + G LECKV G P+ ++WYKDG+ L H+ S + SL
Sbjct: 2371 ---IVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHK-FSFYNKISSL 2426
Query: 352 ----------GTYTCEASNCMGVAASSA 369
GTYT + N +G ++ +A
Sbjct: 2427 RILSVERQDAGTYTFQVQNNVGKSSCTA 2454
Score = 57.6 bits (133), Expect = 7e-07
Identities = 69/299 (23%), Positives = 122/299 (40%), Gaps = 46/299 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F L+ + GL V+ C++ G + W++DG L+ + Q + +++
Sbjct: 2840 PSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKI 2899
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G Y C A N +G ASSSA LT + ++P F S
Sbjct: 2900 LQTDLSHSGQYSCSASNPLGTASSSARLTARE---------------PKKSPFFDIKPVS 2944
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
++ E F V + W +D++ + + L I + D
Sbjct: 2945 IDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPH-LRILKVGKGDS 3003
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEG-AVNLECKVIGVPQ 321
++ C A ND G+ + S L + P P+F++ L+A ++ +G ++ LECK+ G P+
Sbjct: 3004 GQYTCQATNDVGKDMCSAQLSVKEP-----PKFVKKLEASKVAKQGESIQLECKISGSPE 3058
Query: 322 PVLKWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
+ W+++ EL + + + G Y CEA N +G A+ S +L
Sbjct: 3059 IKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTAL 3117
Score = 55.6 bits (128), Expect = 3e-06
Identities = 60/268 (22%), Positives = 104/268 (38%), Gaps = 20/268 (7%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ ECKV G P + W+KDG+ L ++ + N + S ++ Q + + V+
Sbjct: 2387 TLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVE--RQDAGTYTFQVQ 2444
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + + + + + P F LK+ + KVA S+ W+ +
Sbjct: 2445 NNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTK 2504
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHY-KK 293
+ ++ + V L + +L+ D + CVA N G L + P + K+
Sbjct: 2505 IVSGAKYQTTFSDN-VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKE 2563
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
P LE +L + V + G P + W++ EL GD I +D L
Sbjct: 2564 PEPLE----VLPGKN-VTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYF-EDTVAELEL 2617
Query: 352 --------GTYTCEASNCMGVAASSASL 371
G YTC SN G A+ + L
Sbjct: 2618 FNIDISQSGEYTCVVSNNAGQASCTTRL 2645
Score = 55.2 bits (127), Expect = 4e-06
Identities = 63/261 (24%), Positives = 105/261 (40%), Gaps = 12/261 (4%)
Query: 98 PRFMENLQAVLTEEGLVSF-ECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F++ L+ G + +C+V G +SWFKD ++++ Y+L SL C
Sbjct: 496 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSL---VC 552
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+ A V + N++ + + + P FV + + A +
Sbjct: 553 LEIFSFNSADVGEYECV--VANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQA 610
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
V S+ W + + + E + + GV L I ++ ++ C+A N+ G
Sbjct: 611 AVRGSEPISVTWMKGQEVIREDGKIKM-SFSNGVAVLIIPDVQISFGGKYTCLAENEAG- 668
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
S TS +LI+ K E +Q D LE V G P+ KWYKDG L
Sbjct: 669 SQTSVG-ELIVKEPAKIIERAELIQVTAGD--PATLEYTVAGTPELKPKWYKDGRPLVAS 725
Query: 337 DIHRIISGQDGTCSLGTYTCE 357
+R IS ++ L Y+ E
Sbjct: 726 KKYR-ISFKNNVAQLKFYSAE 745
Score = 52.0 bits (119), Expect = 3e-05
Identities = 54/247 (21%), Positives = 101/247 (40%), Gaps = 15/247 (6%)
Query: 98 PRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + + + + +E V +V G P ++WFKD L+ G Y+ + L S
Sbjct: 1058 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQI 1117
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI--DEPFRF 214
+ A+ + E + N++ + + P F+ ++S + F+
Sbjct: 1118 L----KFVAADAGEYQCR-VTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQA 1172
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
T+K ++P ++ W +D + E + E V L + +E ++ C A ND
Sbjct: 1173 TLKGSLP--ITVTWLKDSDEITEDDNIRM-TFENNVASLYLSGIEVKHDGKYVCQAKNDA 1229
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELK 334
G S L + P + E + ++ L+ K G + KW+KDG+EL
Sbjct: 1230 GIQRCSALLSVKEPATITE----EAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELT 1285
Query: 335 PGDIHRI 341
G ++I
Sbjct: 1286 LGSKYKI 1292
Score = 50.8 bits (116), Expect = 8e-05
Identities = 53/224 (23%), Positives = 97/224 (43%), Gaps = 21/224 (9%)
Query: 96 RKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---TGTNSL 151
+ P F ++L V EG V C V G + W K G+E+KP D +GT L
Sbjct: 5009 KPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVL 5068
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL 201
G Y C A N G ++ +++T++D +K + + FV
Sbjct: 5069 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGR---LFFVSEP 5125
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDD-QPVDESSRCHLGKEERGVFFLDIQALEF 260
+S+ F KV P P++ W + + +++ R + ++ L+I+
Sbjct: 5126 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFI-HQKGDEAKLEIRDTTK 5184
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAIL 304
D ++CVAFN+ G+ ++ + L + K+ + +L+A+L
Sbjct: 5185 TDSGLYRCVAFNEHGEIESN--VNLQVDERKKQEKIEGDLRAML 5226
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/230 (22%), Positives = 94/230 (40%), Gaps = 13/230 (5%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V +C++ G P + W KD ++++ +++T + + + +AS E
Sbjct: 3140 VILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNL----EASDVGEYHC 3195
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD-D 232
+ N++ + + P+FV L I + V S++W +D
Sbjct: 3196 K-ATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRG 3254
Query: 233 QPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP-RHY 291
+ + ES + + + L + + E + ++ C ND G S L ++ P R
Sbjct: 3255 EVIRESENTRISFIDN-IATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARII 3313
Query: 292 KKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+KP E + + A LEC V G P+ KW+KDG EL H I
Sbjct: 3314 EKP---EPMTVTTGNPFA--LECVVTGTPELSAKWFKDGRELSADSKHHI 3358
Score = 36.7 bits (81), Expect = 1.3
Identities = 39/187 (20%), Positives = 77/187 (41%), Gaps = 22/187 (11%)
Query: 164 QASSSAELTVEDIQNQLNEEEKL--------QLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
Q + L +E+I+ +E++ Q S+ + + +++ D F
Sbjct: 5282 QEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFE 5341
Query: 216 IKVAIP-PEPSLLWYRDDQPVDESSRCHLGKE-ERGVFFLDIQALEFLDQAEWKCVAFND 273
I + I PE L WY+ + ++ S + + + +R L ++ + DQ ++ V
Sbjct: 5342 IDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHT--LRVKNCQLKDQGNYRLVC--- 5396
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G + S L +I +P + +LQ + EG VP +W+++G L
Sbjct: 5397 -GPHIASAKLTVI------EPAWERHLQDVTLKEGQTCTMTVQFSVPNVKSEWFRNGRIL 5449
Query: 334 KPGDIHR 340
KP H+
Sbjct: 5450 KPQGRHK 5456
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 104 bits (250), Expect = 4e-21
Identities = 91/308 (29%), Positives = 141/308 (45%), Gaps = 53/308 (17%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP 139
S K+I + H P KP ++ L E G +F+C V G ++W KD +E++P
Sbjct: 8127 SAKLILSEHEVPPFFDLKP---VSVDLALGESG--TFKCHVTGTAPIKITWAKDNREIRP 8181
Query: 140 GDVYQLT-------------GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKL 186
G Y++T G G Y C A N G+ S SA L V++
Sbjct: 8182 GGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQE----------- 8230
Query: 187 QLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGK 245
P+F+ L+ S K DE R+ K+ PE +LWY+D+ + ESS+ +
Sbjct: 8231 -------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF 8283
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHY-KKPRFLENLQAIL 304
+ V L++ L D ++ C A N G + +S LK+ P + KKP +E L+
Sbjct: 8284 VD-SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKG-- 8340
Query: 305 SDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGT---------CSLGTYT 355
V+LEC++ G P + WYKD EL+ G ++I+S T +G Y
Sbjct: 8341 ---ADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQ 8397
Query: 356 CEASNCMG 363
C+A+N +G
Sbjct: 8398 CKATNDVG 8405
Score = 88.6 bits (210), Expect = 3e-16
Identities = 68/285 (23%), Positives = 126/285 (44%), Gaps = 20/285 (7%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + +V G+ ++F + G P + WFK +EL PG+ + SL +
Sbjct: 7761 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNI----SLEDFVT 7816
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+ Q S + + + + LF K A FV L + P
Sbjct: 7817 ELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPA-TFVKRLADFSVETGSPIVLEA 7875
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
P S+ W +D+ + +S RC + E+ L+I D A++ C+ N+ GQ
Sbjct: 7876 TYTGTPPISVSWIKDEYLISQSERCSITMTEKST-ILEILESTIEDYAQYSCLIENEAGQ 7934
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
+ + ++ P ++ +P LE+++A++ + L+CKV G P+ + WYK+ +L+
Sbjct: 7935 DICEALVSVLEPPYFIEP--LEHVEAVIGE--PATLQCKVDGTPEIRISWYKEHTKLRSA 7990
Query: 337 DIHR---------IISGQDGTCSLGTYTCEASNCMGVAASSASLL 372
++ ++ + +G Y+C+A N +G ASSA L+
Sbjct: 7991 PAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLV 8035
Score = 84.2 bits (199), Expect = 7e-15
Identities = 77/278 (27%), Positives = 120/278 (43%), Gaps = 26/278 (9%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASS 167
+T+ + + K G WFKDGQEL G Y+++ T+++ I K +
Sbjct: 5517 VTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVS----ILKIISTEKKD 5572
Query: 168 SAELTVEDIQNQLNE---EEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEP 224
S E T E +QN + + ++ + P F LK +++ VA
Sbjct: 5573 SGEYTFE-VQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPI 5631
Query: 225 SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
S+ W++DDQ + S + + FL+I LE D + C A N G + S L
Sbjct: 5632 SIQWFKDDQEISASEKYKFSFHD-NTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLT 5690
Query: 285 LIIPRHYKKPRFLENLQA-ILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
+ P P F+E Q+ ++ V L+ V G +KW+KD +EL G R +
Sbjct: 5691 VKEP-----PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSG-AARSVW 5744
Query: 344 GQDGTCSL----------GTYTCEASNCMGVAASSASL 371
D + SL GTY C+ SN +G A S A+L
Sbjct: 5745 KDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATL 5782
Score = 83.8 bits (198), Expect = 9e-15
Identities = 73/287 (25%), Positives = 126/287 (43%), Gaps = 23/287 (8%)
Query: 99 RFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
+ +E ++V +TE+ ++ EC V G P + W KDG+++ P + ++ N++ S+
Sbjct: 6069 QIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASF--R 6126
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
++ M Q S VE+ + + L++ +N P F L ++ + K
Sbjct: 6127 IQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECK 6186
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ S W++D + + S++ L ER V L++ LE D A + C N G
Sbjct: 6187 VSGSLPISAQWFKDGKEISTSAKYRLVCHERSV-SLEVNNLELEDTANYTCKVSNVAGDD 6245
Query: 278 VTSCFLKLIIPRHY-KKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
S L + P + KP QAI + V + + G P +KW+KD EL G
Sbjct: 6246 ACSGILTVKEPPSFLVKP---GRQQAI--PDSTVEFKAILKGTPPFKIKWFKDDVELVSG 6300
Query: 337 DIHRIISGQDGTCSL-----------GTYTCEASNCMGVAASSASLL 372
+ G +G+ S G YTC +N +G + + LL
Sbjct: 6301 P--KCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLL 6345
Score = 81.4 bits (192), Expect = 5e-14
Identities = 75/284 (26%), Positives = 116/284 (40%), Gaps = 19/284 (6%)
Query: 100 FMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
F++ L E G + E G P +SW KD + + +T T +
Sbjct: 7856 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 7915
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
A S I+N+ ++ L S + P F+ L+ VEA I EP KV
Sbjct: 7916 STIEDYAQYSCL-----IENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKV 7970
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
PE + WY++ + S+ + + + V L I ++ D E+ C A N G
Sbjct: 7971 DGTPEIRISWYKEHTKL-RSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVA 8029
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDG------E 331
+S L+I P F L+ + G V EC++ G + WYKDG
Sbjct: 8030 SSAV--LVIKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDA 8087
Query: 332 ELKPGDIHRIIS---GQDGTCSLGTYTCEASNCMGVAASSASLL 372
L+ +H + + Q +G Y C ASN +G A+SSA L+
Sbjct: 8088 NLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLI 8131
Score = 79.0 bits (186), Expect = 2e-13
Identities = 66/260 (25%), Positives = 110/260 (42%), Gaps = 18/260 (6%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC V G +SW KD +E++ G YQ++ + ++ + K G + V +
Sbjct: 9099 FECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN-SAHLTVLKVDKGDSGQYTCYAVNE 9157
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGL-KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + +L + + P F L ++VE F+ +VA ++ WY+++
Sbjct: 9158 VGKD-SCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIE 9216
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP 294
+ +S C + + L ++ D + C ND G ++ C ++I K P
Sbjct: 9217 IQPTSNCEI-TFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSAL--CTSSIVIKEPKKPP 9273
Query: 295 RFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
F ++L + EG V L C V G ++W K G E+KP D S GT L
Sbjct: 9274 VFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSD-RCSFSFASGTAVLEL 9332
Query: 352 --------GTYTCEASNCMG 363
G Y C+ASN G
Sbjct: 9333 RDVAKADSGDYVCKASNVAG 9352
Score = 78.6 bits (185), Expect = 3e-13
Identities = 70/288 (24%), Positives = 124/288 (43%), Gaps = 22/288 (7%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS--Y 154
P F+ L+ + G VS +C+V G P +SW+K +L+P Y+ TN++ + +
Sbjct: 7006 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVF 7065
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ N G+ + AE ++ + + ++ + P F LK +E + P
Sbjct: 7066 NKVNINDSGEYTCKAENSI----GTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTL 7121
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
T ++ + WYRD + + + V L I + ++ C A N
Sbjct: 7122 TCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVD-NVATLKILQTDLSHSGQYSCSASNPL 7180
Query: 275 GQSVTSCFLKLIIPRHYKKPRF-LENLQA-ILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G + +S L P+ K P F ++ + +++ E A + EC V G + W KD +E
Sbjct: 7181 GTASSSARLTAREPK--KSPFFDIKPVSIDVIAGESA-DFECHVTGAQPMRITWSKDNKE 7237
Query: 333 LKPGDIHRIISGQD---------GTCSLGTYTCEASNCMGVAASSASL 371
++PG + I + G G YTC+A+N +G SA L
Sbjct: 7238 IRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 7285
Score = 78.2 bits (184), Expect = 4e-13
Identities = 56/240 (23%), Positives = 112/240 (46%), Gaps = 13/240 (5%)
Query: 98 PRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F+ L+ V + + V EC+V G P ++W K+ +E++ Y LT S+ +
Sbjct: 5882 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSV--FNL 5939
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
C + + V + + ++ L + P F+ +++ + F
Sbjct: 5940 HITKCDPSDTGEYQCIVSNEGGSCSCSTRVAL---KEPPSFIKKIENTTTVLKSSATFQS 5996
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
VA P S+ W +DDQ +DE ++ + V L I++++ + C A N+ G
Sbjct: 5997 TVAGSPPISITWLKDDQILDEDDNVYISFVD-SVATLQIRSVDNGHSGRYTCQAKNESG- 6054
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
V C+ L++ + + +E +++ ++++ + LEC V G P+ +KW KDG+++ P
Sbjct: 6055 -VERCYAFLLV---QEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVP 6110
Score = 77.0 bits (181), Expect = 1e-12
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVF 251
QAP F L+SV F ++ P P + W+RD Q + S+ + G
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-V 310
L I A+ + + A N GQ+ ++ +L++ P F++ LQ++ +G+ V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTA--ELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 311 NLECKVIGVPQPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNC 361
L+ +V G+P PV+K+Y+DG E+ + GD++ ++ + GTY+ A+N
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 362 MGVAASSASLL 372
+G A S+A LL
Sbjct: 182 VGRATSTAELL 192
Score = 77.0 bits (181), Expect = 1e-12
Identities = 73/286 (25%), Positives = 120/286 (41%), Gaps = 27/286 (9%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
R +E L+ L L F C++ P WFK G+E+ D + + + S +
Sbjct: 4387 RKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR 4444
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRFTI 216
Q E T + N+ + +A P F+ KS+ + + +F
Sbjct: 4445 T----QVVDCGEYTCK-ASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFIC 4499
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
V P +W +D + S + E L++ L D+ + C A N FG
Sbjct: 4500 TVTGTPVIETIWQKDGAALSPSPNWKISDAENK-HILELSNLTIQDRGVYSCKASNKFGA 4558
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSD-EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ C +LII KP F++ L+ + S V+LEC+V + + W KDG++L P
Sbjct: 4559 DI--CQAELII---IDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPP 4613
Query: 336 GDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
G ++I +D +L GTY C ASN G ++ SA++
Sbjct: 4614 GKDYKICF-EDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATV 4658
Score = 76.2 bits (179), Expect = 2e-12
Identities = 72/297 (24%), Positives = 124/297 (41%), Gaps = 23/297 (7%)
Query: 87 SHPTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
S T K P F + + T +G V EC++ G P +SW+KD +EL+ G Y++
Sbjct: 8315 SSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI 8374
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
N L S + + + T N + + + + P+FV L +
Sbjct: 8375 MSENFLTSIHILNVDAADIGEYQCKAT-----NDVGSDTCVGSIALKAPPRFVKKLSDIS 8429
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRD-DQPVDESSRCHLGKEERGVFFLDIQALEFLDQA 264
+ + + + S++W++D + V ES + E + L +E +
Sbjct: 8430 TVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSE-NIATLQFSRVEPANAG 8488
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRH-YKKPRFLENLQAILSDEGAVNLECKVIGVPQPV 323
++ C ND G L ++ P +KP E+++ D LEC V G P+
Sbjct: 8489 KYTCQIKNDAGMQECFATLSVLEPATIVEKP---ESIKVTTGD--TCTLECTVAGTPELS 8543
Query: 324 LKWYKDGEELKPGDIHRI-----ISG----QDGTCSLGTYTCEASNCMGVAASSASL 371
KW+KDG+EL + ++I +SG G Y+ E N +G + +ASL
Sbjct: 8544 TKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASL 8600
Score = 75.8 bits (178), Expect = 2e-12
Identities = 76/299 (25%), Positives = 129/299 (43%), Gaps = 44/299 (14%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F++ L+ V G S +C++ G P +SW+K +L+P Y++ N++
Sbjct: 8888 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVF 8947
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G Y C A+N +G+ S+S LTV +E+KL P F L+
Sbjct: 8948 NQVDINDSGEYICKAENSVGEVSASTFLTV--------QEQKL-------PPSFSRQLRD 8992
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
V+ + P F ++ S+ WY+D +P+ +S + L+I +
Sbjct: 8993 VQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLD-NTATLNIFKTDRSLA 9051
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQP 322
++ C A N G + +S +LI+ P F L + + G + + EC V G
Sbjct: 9052 GQYSCTATNPIGSASSSA--RLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPI 9109
Query: 323 VLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
+ W KD E++ G ++ IS + + L G YTC A N +G + +A L
Sbjct: 9110 KVSWAKDSREIRSGGKYQ-ISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL 9167
Score = 75.4 bits (177), Expect = 3e-12
Identities = 67/267 (25%), Positives = 116/267 (43%), Gaps = 22/267 (8%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC V G ++W KD +E++PG Y +T + + I K G + D
Sbjct: 7217 FECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNT-PHLRILKVGKGDSGQYTCQATND 7275
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + + S + PKFV L++ + AK E + K++ PE + W+R+D
Sbjct: 7276 VGKDMCSAQ----LSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSE 7331
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP 294
+ ES + ++ V L I D ++ C A N G + S L + P P
Sbjct: 7332 LHESWKYNMSFIN-SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAP-----P 7385
Query: 295 RFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGT----- 348
F + + + +G+ V L+C++ G P + W KD ++++ +I S T
Sbjct: 7386 VFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHIL 7445
Query: 349 ----CSLGTYTCEASNCMGVAASSASL 371
+G Y C+A+N +G S S+
Sbjct: 7446 NLEASDVGEYHCKATNEVGSDTCSCSV 7472
Score = 75.4 bits (177), Expect = 3e-12
Identities = 82/308 (26%), Positives = 125/308 (40%), Gaps = 43/308 (13%)
Query: 90 TVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQ---L 145
TV + P F L+ V GL V F+C + G +SW+KDG+ LK Q L
Sbjct: 8976 TVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFL 9035
Query: 146 TGTNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
T +L G Y C A N +G ASSSA L + + +N P
Sbjct: 9036 DNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNP---------------P 9080
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDI 255
F L V+A + E F V + W +D + + + + E L +
Sbjct: 9081 FFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAH-LTV 9139
Query: 256 QALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSD-EG-AVNLE 313
++ D ++ C A N+ G+ SC +L I P F + L + + EG + LE
Sbjct: 9140 LKVDKGDSGQYTCYAVNEVGKD--SCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLE 9197
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD---------GTCSLGTYTCEASNCMGV 364
+V G + WYK+ E++P I + G G YTC+ SN G
Sbjct: 9198 GRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGS 9257
Query: 365 AASSASLL 372
A ++S++
Sbjct: 9258 ALCTSSIV 9265
Score = 74.9 bits (176), Expect = 4e-12
Identities = 64/270 (23%), Positives = 115/270 (42%), Gaps = 22/270 (8%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
+ ECKV G WFKDG+E+ Y+L S + N + + +A T
Sbjct: 6181 IHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVS---LEVNNL-ELEDTANYTC 6236
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+ + N ++ + + + P F+ +A D F + P + W++DD
Sbjct: 6237 K-VSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDV 6295
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ +C +G E FL++ +++ ++ C ND G SC L++ +
Sbjct: 6296 ELVSGPKCFIGLEG-STSFLNLYSVDASKTGQYTCHVTNDVGSD--SCTTMLLVT---EP 6349
Query: 294 PRFLENLQA--ILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHR---------II 342
P+F++ L+A I+ + LECK+ G P+ + W+++ EL D +R I
Sbjct: 6350 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 6409
Query: 343 SGQDGTCSLGTYTCEASNCMGVAASSASLL 372
T G + CEA N G + S ++
Sbjct: 6410 MNNLSTEDSGDFICEAQNPAGSTSCSTKVI 6439
Score = 73.7 bits (173), Expect = 9e-12
Identities = 85/302 (28%), Positives = 125/302 (41%), Gaps = 52/302 (17%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----------- 145
P F L+ V G V+FEC++ G +SW+KDG LK Q
Sbjct: 8043 PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQI 8102
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK- 202
T + +G Y C A N +G ASSSA+L + S+++ P F LK
Sbjct: 8103 LQTDQSHIGQYNCSASNPLGTASSSAKL----------------ILSEHEVPPFFD-LKP 8145
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
SV+ + E F V + W +D++ + + E L + +
Sbjct: 8146 VSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTAT-LTVLKVGKG 8204
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQA--ILSDEGAVNLECKVIGV 319
D ++ C A N G+ S L + P PRF++ L+ I+ + ECK+ G
Sbjct: 8205 DAGQYTCYASNIAGKDSCSAHLGVQEP-----PRFIKKLEPSRIVKQDEFTRYECKIGGS 8259
Query: 320 PQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSA 369
P+ + WYKD E++ R+ S D L G YTCEA N G A+SS
Sbjct: 8260 PEIKVLWYKDETEIQESSKFRM-SFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 8318
Query: 370 SL 371
SL
Sbjct: 8319 SL 8320
Score = 72.5 bits (170), Expect = 2e-11
Identities = 69/270 (25%), Positives = 111/270 (41%), Gaps = 23/270 (8%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V ECKV G P +SWF +G E+ G YQ T T++ C + N M + S S + T
Sbjct: 8626 VVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT---CALTVN-MLEESDSGDYTC 8681
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +E + + P FV ++ FT V P S+ W++
Sbjct: 8682 -IATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSS 8740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ RC++ E+ V L++ ++ E+ C+ N+ G++ SC L I K
Sbjct: 8741 ELVPGDRCNVSLED-SVAELELFDVDTSQSGEYTCIVSNEAGKA--SCTTHLYI----KA 8793
Query: 294 P-RFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC-- 349
P +F++ L ++G + LE G P + W K+G + P I + +
Sbjct: 8794 PAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILE 8853
Query: 350 -------SLGTYTCEASNCMGVAASSASLL 372
G Y C N G + SA +L
Sbjct: 8854 IPSSTVEDAGQYNCYIENASGKDSCSAQIL 8883
Score = 72.1 bits (169), Expect = 3e-11
Identities = 76/300 (25%), Positives = 123/300 (41%), Gaps = 51/300 (17%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVY------------- 143
P F + L+ + + +G + EC V G + WFKD QE+ + Y
Sbjct: 5602 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 5661
Query: 144 -QLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
QL GT+S G+Y C A N G S LTV++ P FV +
Sbjct: 5662 SQLEGTDS-GTYTCSATNKAGHNQCSGHLTVKE------------------PPYFVEKPQ 5702
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
S + + + V ++ W++D++ + + + K++ L++ A + D
Sbjct: 5703 SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTS-LELFAAKATD 5761
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHY-KKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
+ C ND G + + L + P + KKP + +L + + EC++ G P+
Sbjct: 5762 SGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPV----LVLRNGQSTTFECQITGTPK 5817
Query: 322 PVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
+ WY DG E+ H IS DG + GTY CEA N G A+ S L
Sbjct: 5818 IRVSWYLDGNEITAIQKHG-ISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIEL 5876
Score = 71.3 bits (167), Expect = 5e-11
Identities = 59/231 (25%), Positives = 96/231 (41%), Gaps = 30/231 (12%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C A N G+ ++SA+LTV K AP ++ +E +
Sbjct: 4356 GEYVCEALNDSGKTATSAKLTVV----------------KRAAPVIKRKIEPLEVALGHL 4399
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
+FT ++ P W++ + + ES +C + + + + L+I + +D E+ C A
Sbjct: 4400 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 4458
Query: 272 NDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDG 330
N++G SC L + Y P FL +++ + G A C V G P W KDG
Sbjct: 4459 NEYGS--VSCTATLTVTEAY-PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDG 4515
Query: 331 EELKPGDIHRIISGQDGTC---------SLGTYTCEASNCMGVAASSASLL 372
L P +I ++ G Y+C+ASN G A L+
Sbjct: 4516 AALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELI 4566
Score = 71.3 bits (167), Expect = 5e-11
Identities = 80/300 (26%), Positives = 124/300 (41%), Gaps = 49/300 (16%)
Query: 98 PRFMENLQAVLTEEG--LVSFECKVVGFPTPVLSWFKDGQEL----KPG-------DVYQ 144
P+F++ VL +FEC++ G P +SW+ DG E+ K G +Q
Sbjct: 5788 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQ 5847
Query: 145 LTGTN--SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
++G + G+Y C A+N G AS S EL V++ P F+ LK
Sbjct: 5848 ISGARVENSGTYVCEARNDAGTASCSIELKVKE------------------PPTFIRELK 5889
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
VE +V P + W ++++ + S + L + VF L I + D
Sbjct: 5890 PVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL-TDRVSVFNLHITKCDPSD 5948
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQP 322
E++C+ N+ G S + L P + K +EN +L + + + V G P
Sbjct: 5949 TGEYQCIVSNEGGSCSCSTRVALKEPPSFIKK--IENTTTVL--KSSATFQSTVAGSPPI 6004
Query: 323 VLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ W KD + L D + IS D +L G YTC+A N GV A LL
Sbjct: 6005 SITWLKDDQILDEDD-NVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLL 6063
Score = 70.5 bits (165), Expect = 9e-11
Identities = 54/198 (27%), Positives = 91/198 (45%), Gaps = 22/198 (11%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+ + L+ V + +P RF ++ P+P + WY+++Q + +C + +
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK--------KPRFLENLQAIL 304
L I+A D A + C A ND+G + TS L + +P P + LQ +
Sbjct: 3297 LLIEAFP-EDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3355
Query: 305 SDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GT 353
+ EG +C+V G V WY +++KP R+ +D T L GT
Sbjct: 3356 TSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGT 3413
Query: 354 YTCEASNCMGVAASSASL 371
YT ASN +G +S+A+L
Sbjct: 3414 YTFVASNAVGQVSSTANL 3431
Score = 70.1 bits (164), Expect = 1e-10
Identities = 75/303 (24%), Positives = 131/303 (43%), Gaps = 53/303 (17%)
Query: 97 KPRFMENLQAVLTE-EGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
KP F++ L+ V + V EC+V ++W KDGQ+L PG Y++ + +
Sbjct: 4570 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE 4629
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G+Y C A N G +S SA +TV + + F K P ++
Sbjct: 4630 IPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS----------FVKKVDPSYL---- 4675
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS--RCHLGKEERGVFFLDIQALEF 260
E R K+ P + W+++++ + ES+ R + E LDI ++
Sbjct: 4676 ---MLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEA---ILDITDVKV 4729
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQA--ILSDEGAVNLECKVIG 318
D + C A ND G SC +++I + P F++ L+ I+ A+ L+C+V G
Sbjct: 4730 EDSGSYSCEAVNDVGSD--SCSTEIVIK---EPPSFIKTLEPADIVRGTNAL-LQCEVSG 4783
Query: 319 VPQPVLKWYKDGEELKPGDIHRIISGQDGTC---------SLGTYTCEASNCMGVAASSA 369
+ W+KD ++++ +R+ S + C +G Y C +N +G A
Sbjct: 4784 TGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMA 4843
Query: 370 SLL 372
+ L
Sbjct: 4844 THL 4846
Score = 68.9 bits (161), Expect = 3e-10
Identities = 67/268 (25%), Positives = 108/268 (40%), Gaps = 20/268 (7%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ EC V G P WFKDG+EL + +T N + S + S E V+
Sbjct: 7590 ALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFE--VK 7647
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + N + + + P F+ LK V A + +V+ S+ W++D
Sbjct: 7648 NSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNE 7707
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK- 293
+ +C E V L++ LE D + CVA N G S L + P +++
Sbjct: 7708 IVSGPKCQSSFSE-NVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT 7766
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
P +E L + ++ + G P +KW+K EL PG+ IS +D L
Sbjct: 7767 PDSVEVLPGM-----SLTFTSVIRGTPPFKVKWFKGSRELVPGESCN-ISLEDFVTELEL 7820
Query: 352 --------GTYTCEASNCMGVAASSASL 371
G Y+C +N G A+ + L
Sbjct: 7821 FEVQPLESGDYSCLVTNDAGSASCTTHL 7848
Score = 68.1 bits (159), Expect = 5e-10
Identities = 76/279 (27%), Positives = 120/279 (43%), Gaps = 40/279 (14%)
Query: 98 PRFMENLQA--VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
P+F++ L+A V + + ECK+ G P +SWF++ EL Y ++ NS+
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT 7350
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G Y C A N +G AS S LTV + +F++ +P V LK
Sbjct: 7351 INEASAEDSGDYICEAHNGVGDASCSTALTV----------KAPPVFTQKPSP--VGALK 7398
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
+ + +++ P ++W +D + V S + + + L I LE D
Sbjct: 7399 GSDVILQ------CEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDT-SLHILNLEASD 7451
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQP 322
E+ C A N+ G SC +K P + K L + ++ D AV L V G
Sbjct: 7452 VGEYHCKATNEVGSDTCSCSVKFKEPPRFVKK--LSDTSTLIGD--AVELRAIVEGFQPI 7507
Query: 323 VLKWYKD-GEELKPGDIHRIISGQDGTCSLGTYTCEASN 360
+ W KD GE ++ + R IS D +L + EASN
Sbjct: 7508 SVVWLKDRGEVIRESENTR-ISFIDNIATLQLGSPEASN 7545
Score = 66.9 bits (156), Expect = 1e-09
Identities = 61/234 (26%), Positives = 101/234 (43%), Gaps = 37/234 (15%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C+A+N G +S EL V++ K + + ++ +P
Sbjct: 4919 GKYTCLAENEAGSQTSVGELIVKE------------------PAKIIERAELIQVTAGDP 4960
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
VA PE WY+D +P+ S + + + V L + E D ++
Sbjct: 4961 ATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNN-VAQLKFYSAELHDSGQYTFEIS 5019
Query: 272 NDFGQS---VTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK 328
N+ G S T L I + KP L N+ ++++ G L+CK+ G + W+K
Sbjct: 5020 NEVGSSSCETTFTVLDRDIAPFFTKP--LRNVDSVVN--GTCRLDCKIAGSLPMRVSWFK 5075
Query: 329 DGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
DG+E+ D +R I+ +GT SL G +TC A+N +G SS +L+
Sbjct: 5076 DGKEIAASDRYR-IAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALI 5128
Score = 66.5 bits (155), Expect = 1e-09
Identities = 50/175 (28%), Positives = 77/175 (44%), Gaps = 3/175 (1%)
Query: 179 QLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES 238
+L E ++ QL + P FV S + + RF +KV P P W+ D Q +
Sbjct: 1442 RLEETDESQL-ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVND 1500
Query: 239 SRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLE 298
+ +E G L I D EW VA N G+S S L + H KP F+E
Sbjct: 1501 YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560
Query: 299 NLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL 351
L+ + EG+ + ++ + G P P + W K+ + + P +I I G G +L
Sbjct: 1561 KLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL 1615
Score = 64.9 bits (151), Expect = 4e-09
Identities = 68/283 (24%), Positives = 112/283 (39%), Gaps = 19/283 (6%)
Query: 100 FMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
F++ L E G + E G ++W KDG + + + T CI
Sbjct: 6915 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKT----CIL 6970
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ + + + E I+N+ + L S + P FV L+ +EA + + +V
Sbjct: 6971 EILNSTKRDAGQYSCE-IENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQV 7029
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
A PE ++ WY+ D + + + V L + D E+ C A N G +
Sbjct: 7030 AGTPEITVSWYKGDTKLRPTPE-YRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTAS 7088
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDG------E 331
+ + I P F L+ I G V L C++ G + WY+DG E
Sbjct: 7089 SKTVFR--IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDE 7146
Query: 332 ELKPGDIHRIIS---GQDGTCSLGTYTCEASNCMGVAASSASL 371
L+ + + + Q G Y+C ASN +G A+SSA L
Sbjct: 7147 NLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 7189
Score = 63.7 bits (148), Expect = 1e-08
Identities = 77/295 (26%), Positives = 125/295 (42%), Gaps = 56/295 (18%)
Query: 95 YRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL 151
+ KP + N+ +V+ G +CK+ G +SWFKDG+E+ D Y++ GT SL
Sbjct: 5042 FTKP--LRNVDSVVN--GTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 5097
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL 201
G++ C A N +G SS L V++ + + + SK+ P L
Sbjct: 5098 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPG-----SKDVLPGSAVCL 5152
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
KS T + + P ++ W++ ++ + C++ KE L++ ++
Sbjct: 5153 KS-----------TFQGSTPL--TIRWFKGNKELVSGGSCYITKEALESS-LELYLVKTS 5198
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR-FLENLQA--ILSDEGAVNLECKVIG 318
D + C N G C L + K+P F+E L+ +L A L CKV G
Sbjct: 5199 DSGTYTCKVSNVAGG--VECSANLFV----KEPATFVEKLEPSQLLKKGDATQLACKVTG 5252
Query: 319 VPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMG 363
P + W+ + E+K HR +S + T L G Y CEA N G
Sbjct: 5253 TPPIKITWFANDREIKESSKHR-MSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 5306
Score = 62.9 bits (146), Expect = 2e-08
Identities = 67/270 (24%), Positives = 112/270 (41%), Gaps = 24/270 (8%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ E V G P W+KDG+ L Y+++ N++ K + S + T E
Sbjct: 4962 TLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQL----KFYSAELHDSGQYTFE 5017
Query: 175 DIQNQLNE---EEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD 231
I N++ E + ++ AP F L++V++ ++ R K+A + W++D
Sbjct: 5018 -ISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKD 5076
Query: 232 DQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHY 291
+ + S R + E G L+I ++ D + C A N G +S L + P +
Sbjct: 5077 GKEIAASDRYRIAFVE-GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSF 5135
Query: 292 -KKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC 349
KP + L AV L+ G ++W+K +EL G I + +
Sbjct: 5136 VTKPGSKDVLPG-----SAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSL 5190
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
L GTYTC+ SN G SA+L
Sbjct: 5191 ELYLVKTSDSGTYTCKVSNVAGGVECSANL 5220
Score = 62.5 bits (145), Expect = 2e-08
Identities = 60/249 (24%), Positives = 106/249 (42%), Gaps = 13/249 (5%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYC 155
P+ E +Q+ +G F +VVG P P W+K+G +++ D +Y +++
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE-- 2135
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
+ ++ + S+S + +I + + L L Q F L+ V AK +
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLITFTQELQDVVAKEKDTMATF 2194
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
P + WY+D V E + + +R V FL I ++ D ++ CV D
Sbjct: 2195 ECETSEPFVKVKWYKDGMEVHEGDKYRM-HSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2253
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELK 334
T+ KLI+ + F++ LQ I + + + LEC ++ KWY + ELK
Sbjct: 2254 VKTTA---KLIVEGAVVE--FVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELK 2307
Query: 335 PGDIHRIIS 343
+ I S
Sbjct: 2308 SNGKYTITS 2316
Score = 62.5 bits (145), Expect = 2e-08
Identities = 66/286 (23%), Positives = 117/286 (40%), Gaps = 21/286 (7%)
Query: 99 RFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
+F++ L E+G + E G P ++W K+G + P +T T S
Sbjct: 8796 KFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK--SAILE 8853
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
+ + + +E+ + + ++ + + P FV L+ V+ + + +
Sbjct: 8854 IPSSTVEDAGQYNCYIENASGKDSCSAQILIL---EPPYFVKQLEPVKVSVGDSASLQCQ 8910
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+A PE + WY+ D + ++ + V L ++ D E+ C A N G+
Sbjct: 8911 LAGTPEIGVSWYKGDTKLRPTTTYKM-HFRNNVATLVFNQVDINDSGEYICKAENSVGEV 8969
Query: 278 VTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPG 336
S FL + P F L+ + G V +C + G + WYKDG+ LK
Sbjct: 8970 SASTFLT--VQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDS 9027
Query: 337 DIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ S D T +L G Y+C A+N +G A+SSA L+
Sbjct: 9028 PNVQT-SFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLI 9072
Score = 62.1 bits (144), Expect = 3e-08
Identities = 69/289 (23%), Positives = 124/289 (42%), Gaps = 29/289 (10%)
Query: 87 SHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT 146
S VP ++ R ++N VL ++ ECKV G ++WF + ++ G YQ T
Sbjct: 6721 SDRAVPPSFT--RRLKNTGGVLGASCIL--ECKVAGSSPISVAWFHEKTKIVSGAKYQTT 6776
Query: 147 GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
++++ C + N + + V N +E + + + P FV + +E
Sbjct: 6777 FSDNV---CTLQLNSLDSSDMGNYTCVA--ANVAGSDECRAVLTVQEPPSFVKEPEPLEV 6831
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+ FT + P + W+R + + + RC++ E+ V L++ ++ E+
Sbjct: 6832 LPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT-VAELELFNIDISQSGEY 6890
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKP-RFLENLQAILSDEG-AVNLECKVIGVPQPVL 324
CV N+ GQ+ SC +L + K+P FL+ L + G ++ LE G +
Sbjct: 6891 TCVVSNNAGQA--SCTTRLFV----KEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISV 6944
Query: 325 KWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMG 363
W KDG + + I++ + TC L G Y+CE N G
Sbjct: 6945 TWKKDGFNITTSEKCNIVT-TEKTCILEILNSTKRDAGQYSCEIENEAG 6992
Score = 61.7 bits (143), Expect = 4e-08
Identities = 61/252 (24%), Positives = 109/252 (43%), Gaps = 40/252 (15%)
Query: 98 PRFMENLQAV-LTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT--------- 146
P+F++ L+A + + G S ECK+ G P + WF++ EL D Y++T
Sbjct: 6350 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 6409
Query: 147 ----GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
T G + C A+N G S S ++ V++ +FS P V LK
Sbjct: 6410 MNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE----------PPVFS--SFPPIVETLK 6457
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
+ E ++ +++ P ++WY+D + + S + + + + I ++ D
Sbjct: 6458 NAEVSLE------CELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHT-SIHILNVDTSD 6510
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQ 321
E+ C A N+ G C +KL P PRF+ L ++ G L+ + G
Sbjct: 6511 IGEYHCKAQNEVGSDTCVCTVKLKEP-----PRFVSKLNSLTVVAGEPAELQASIEGAQP 6565
Query: 322 PVLKWYKDGEEL 333
++W K+ EE+
Sbjct: 6566 IFVQWLKEKEEV 6577
Score = 61.3 bits (142), Expect = 5e-08
Identities = 64/285 (22%), Positives = 116/285 (40%), Gaps = 25/285 (8%)
Query: 100 FMENLQA--VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
F+E L+ +L + CKV G P ++WF + +E+K ++++ S +
Sbjct: 5228 FVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTA---VL 5284
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
+G S E E QN+ + + ++P F K +E + +
Sbjct: 5285 RLTDVG-IEDSGEYMCE-AQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAE 5342
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
VA P + W++D+ + S R + + + L I D E++C N+ G S
Sbjct: 5343 VAGTPPFEITWFKDN-TILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 5401
Query: 278 VTSCFLKLIIPRHYKKPRFLENLQAILS-DEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
+ S + L P P F++ +++ S G + + G + W KD +E+
Sbjct: 5402 ICSARVTLREP-----PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITED 5456
Query: 337 DIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
D R ++ ++ SL G Y C+A N G+ SA L
Sbjct: 5457 DNIR-MTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL 5500
Score = 60.5 bits (140), Expect = 9e-08
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 2/187 (1%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + LQ+V+ EG +FE + GFP P +SWF+DGQ + + + + S G
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
S L + Q +L + ++ P FV L+S+ + R +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+V P P + +YRD + S + +E ++ L I D + A N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 277 SVTSCFL 283
+ ++ L
Sbjct: 185 ATSTAEL 191
Score = 59.3 bits (137), Expect = 2e-07
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 6/162 (3%)
Query: 184 EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
+K++L +APK ++S F ++V P+P WY++ ++ S R +
Sbjct: 2067 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2126
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI 303
E V L I+ + D A A N G++ + FL + + + F + LQ +
Sbjct: 2127 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL---LVQAKQLITFTQELQDV 2183
Query: 304 LSDE--GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
++ E EC+ P +KWYKDG E+ GD +R+ S
Sbjct: 2184 VAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHS 2224
Score = 58.8 bits (136), Expect = 3e-07
Identities = 58/248 (23%), Positives = 104/248 (41%), Gaps = 18/248 (7%)
Query: 84 IHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVY 143
+H S VP ++ R ++++ A+L V EC+V G + WF+DG E+ G
Sbjct: 7659 VHVSDRIVPPSFI--RKLKDVNAILGAS--VVLECRVSGSAPISVGWFQDGNEIVSGPKC 7714
Query: 144 QLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
Q +S C + + S + T N +E + + + P F S
Sbjct: 7715 Q----SSFSENVCTLNLSLLEPSDTGIYTCV-AANVAGSDECSAVLTVQEPPSFEQTPDS 7769
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
VE FT + P + W++ + + C++ E+ V L++ ++ L+
Sbjct: 7770 VEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLED-FVTELELFEVQPLES 7828
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP-RFLENLQAILSDEGA-VNLECKVIGVPQ 321
++ C+ ND G + SC L + K+P F++ L + G+ + LE G P
Sbjct: 7829 GDYSCLVTNDAGSA--SCTTHLFV----KEPATFVKRLADFSVETGSPIVLEATYTGTPP 7882
Query: 322 PVLKWYKD 329
+ W KD
Sbjct: 7883 ISVSWIKD 7890
Score = 58.8 bits (136), Expect = 3e-07
Identities = 66/287 (22%), Positives = 119/287 (41%), Gaps = 22/287 (7%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKD-GQELKPGDVYQLTGTNSLGSYC 155
PRF++ L + T G V + + G + WFKD G+ ++ D ++ + ++ +
Sbjct: 8419 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATL- 8477
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
+ + +++ + T + I+N +E S + V +S++ +
Sbjct: 8478 ---QFSRVEPANAGKYTCQ-IKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLE 8533
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
VA PE S W++D + + ++ + + V L I + D + N G
Sbjct: 8534 CTVAGTPELSTKWFKDGKELTSDNKYKISFFNK-VSGLKIINVAPSDSGVYSFEVQNPVG 8592
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELK 334
+ SC L + P F L+ G+ V +ECKV G P + W+ +G E+
Sbjct: 8593 KD--SCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEIS 8650
Query: 335 PGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASL 371
G ++ + D TC+L G YTC A+N G SA L
Sbjct: 8651 SGRKYQ-TTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPL 8696
Score = 58.4 bits (135), Expect = 4e-07
Identities = 70/255 (27%), Positives = 114/255 (44%), Gaps = 31/255 (12%)
Query: 100 FMENLQAVLTEEG--LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
F + LQ V+ +E + +FEC+ P + W+KDG E+ GD Y++ + + I
Sbjct: 2176 FTQELQDVVAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKV-HFLSI 2233
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
A + + VED N + +L + +FV L+ +E + E + ++
Sbjct: 2234 LTIDTSDAEDYSCVLVEDE----NVKTTAKLIVEGAVVEFVKELQDIE--VPESYSGELE 2287
Query: 218 VAIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+ PE WY +D + + + + RG L ++ + DQ E+ V
Sbjct: 2288 CIVSPENIEGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFV----IDG 2342
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSD----EG-AVNLECKVIGVPQPVLKWYKDGE 331
T+C LK+ KPR + LQ LSD EG V LE KV + W KDG+
Sbjct: 2343 KKTTCKLKM-------KPRPIAILQG-LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQ 2393
Query: 332 ELKPGD-IHRIISGQ 345
E++P D +H +I Q
Sbjct: 2394 EVQPSDRVHIVIDKQ 2408
Score = 58.4 bits (135), Expect = 4e-07
Identities = 63/268 (23%), Positives = 108/268 (40%), Gaps = 24/268 (8%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS EC++ G P + W+KD ++L+ Y++ N S + + S E
Sbjct: 6461 VSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVD----TSDIGEYHC 6516
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD-D 232
+ QN++ + + + P+FV L S+ EP + + W ++ +
Sbjct: 6517 K-AQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKE 6575
Query: 233 QPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK 292
+ + ES + E V L E + ++ C ND G L ++ P
Sbjct: 6576 EVIRESENIRITFVEN-VATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLEPAV-- 6632
Query: 293 KPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL 351
+E + G LECKV G P+ ++WYKDG+ L H+ S + SL
Sbjct: 6633 ---IVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHK-FSFYNKISSL 6688
Query: 352 ----------GTYTCEASNCMGVAASSA 369
GTYT + N +G ++ +A
Sbjct: 6689 RILSVERQDAGTYTFQVQNNVGKSSCTA 6716
Score = 58.0 bits (134), Expect = 5e-07
Identities = 69/299 (23%), Positives = 122/299 (40%), Gaps = 46/299 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F L+ + GL V+ C++ G + W++DG L+ + Q + +++
Sbjct: 7102 PSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKI 7161
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G Y C A N +G ASSSA LT + ++P F S
Sbjct: 7162 LQTDLSHSGQYSCSASNPLGTASSSARLTARE---------------PKKSPFFDIKPVS 7206
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
++ E F V + W +D++ + + L I + D
Sbjct: 7207 IDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPH-LRILKVGKGDS 7265
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEG-AVNLECKVIGVPQ 321
++ C A ND G+ + S L + P P+F++ L+A ++ +G ++ LECK+ G P+
Sbjct: 7266 GQYTCQATNDVGKDMCSAQLSVKEP-----PKFVKKLEASKVAKQGESIQLECKISGSPE 7320
Query: 322 PVLKWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
+ W+++ EL + + + G Y CEA N +G A+ S +L
Sbjct: 7321 IKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTAL 7379
Score = 57.2 bits (132), Expect = 9e-07
Identities = 84/302 (27%), Positives = 124/302 (41%), Gaps = 53/302 (17%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ---------------LTGTNSLG 152
L E G V F C+V G P P + W K G L G Y+ +T + G
Sbjct: 1093 LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1152
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA------ 206
Y + +N G+ S+SA L +E+ +L + + ++ + Q FV K E
Sbjct: 1153 EYTIVVRNKHGETSASASL-LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVY 1211
Query: 207 ----KIDEPFRFTIKVAIPPEPSLL-WYRDDQPVDESS-RCHLGKE-ERGVFFLDIQALE 259
K E + I+ + + ++ Y +DQ SS L KE E + ++ L
Sbjct: 1212 SEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELL 1271
Query: 260 FLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D E V ++ ++V S F I K R LE + V CK+ G
Sbjct: 1272 EEDGEEKMAVDISE-SEAVESGFDLRI-----KNYRILEGM--------GVTFHCKMSGY 1317
Query: 320 PQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSA 369
P P + WYKDG+ +K G+ +++ QDG SL G YT ASN G A S
Sbjct: 1318 PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSG 1377
Query: 370 SL 371
L
Sbjct: 1378 KL 1379
Score = 56.8 bits (131), Expect = 1e-06
Identities = 59/251 (23%), Positives = 108/251 (43%), Gaps = 21/251 (8%)
Query: 98 PRFMENLQAVLTEEGLVSFECKVV-GFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ ++ LQ V + G + C V+ G P P +SW+K+ Q L G Y L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3298
Query: 148 TNSLGS----YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+ Y C AKN G A++SA L+VE + ++ ++++ ++ P + L+
Sbjct: 3299 IEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVY----PPAIITPLQD 3353
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+P RF +V+ + + WY D+ + + SR + + L+I D+
Sbjct: 3354 TVTSEGQPARFQCRVS-GTDLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDE 3411
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPV 323
+ VA N GQ ++ L L P R + ++ + + + L + G+
Sbjct: 3412 GTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAE 3471
Query: 324 LKWYKDGEELK 334
L+ K E L+
Sbjct: 3472 LQLSKINETLE 3482
Score = 56.4 bits (130), Expect = 2e-06
Identities = 53/201 (26%), Positives = 84/201 (41%), Gaps = 29/201 (14%)
Query: 97 KPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL 151
KP F+ + EG + F+ KVVG P P WF DGQ++ +++ GT SL
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL 201
G + +A+N G++S S LTVE +++Q+ P FV L
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVK-------------PMFVEKL 1562
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVFFLDIQALEF 260
K+V K ++ P P ++W ++ + + E +G L I +
Sbjct: 1563 KNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVS 1622
Query: 261 LDQAEWKCVAFNDFGQSVTSC 281
D A + A N G+ T C
Sbjct: 1623 QDSAWYTATAINKAGRDTTRC 1643
Score = 55.6 bits (128), Expect = 3e-06
Identities = 60/268 (22%), Positives = 104/268 (38%), Gaps = 20/268 (7%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ ECKV G P + W+KDG+ L ++ + N + S ++ Q + + V+
Sbjct: 6649 TLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVE--RQDAGTYTFQVQ 6706
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + + + + + P F LK+ + KVA S+ W+ +
Sbjct: 6707 NNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTK 6766
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHY-KK 293
+ ++ + V L + +L+ D + CVA N G L + P + K+
Sbjct: 6767 IVSGAKYQTTFSDN-VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKE 6825
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
P LE +L + V + G P + W++ EL GD I +D L
Sbjct: 6826 PEPLE----VLPGKN-VTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYF-EDTVAELEL 6879
Query: 352 --------GTYTCEASNCMGVAASSASL 371
G YTC SN G A+ + L
Sbjct: 6880 FNIDISQSGEYTCVVSNNAGQASCTTRL 6907
Score = 55.2 bits (127), Expect = 4e-06
Identities = 63/261 (24%), Positives = 105/261 (40%), Gaps = 12/261 (4%)
Query: 98 PRFMENLQAVLTEEGLVSF-ECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F++ L+ G + +C+V G +SWFKD ++++ Y+L SL C
Sbjct: 4758 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSL---VC 4814
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+ A V + N++ + + + P FV + + A +
Sbjct: 4815 LEIFSFNSADVGEYECV--VANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQA 4872
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
V S+ W + + + E + + GV L I ++ ++ C+A N+ G
Sbjct: 4873 AVRGSEPISVTWMKGQEVIREDGKIKM-SFSNGVAVLIIPDVQISFGGKYTCLAENEAG- 4930
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
S TS +LI+ K E +Q D LE V G P+ KWYKDG L
Sbjct: 4931 SQTSVG-ELIVKEPAKIIERAELIQVTAGD--PATLEYTVAGTPELKPKWYKDGRPLVAS 4987
Query: 337 DIHRIISGQDGTCSLGTYTCE 357
+R IS ++ L Y+ E
Sbjct: 4988 KKYR-ISFKNNVAQLKFYSAE 5007
Score = 52.0 bits (119), Expect = 3e-05
Identities = 47/211 (22%), Positives = 95/211 (45%), Gaps = 36/211 (17%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS--RCHLGKEERGVFF 252
P F+ + + + + + ++ V P+P + W+ + + S+ + ++ +
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL--------------IIPRHYKK----- 293
L LE D+ E+ C+A ND+G+++ S +LK+ + + +K
Sbjct: 3563 L-FTKLE--DEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC 3619
Query: 294 -PRFLENLQAILSDEGAVNL-ECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL 351
P FL+ L+ I +G + E V+G P P + W+K+ ++L + II +G+ +
Sbjct: 3620 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 3679
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G Y C+A N +G + +A LL
Sbjct: 3680 IVNDPQREDSGLYICKAENMLGESTCAAELL 3710
Score = 52.0 bits (119), Expect = 3e-05
Identities = 54/247 (21%), Positives = 101/247 (40%), Gaps = 15/247 (6%)
Query: 98 PRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + + + + +E V +V G P ++WFKD L+ G Y+ + L S
Sbjct: 5320 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQI 5379
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI--DEPFRF 214
+ A+ + E + N++ + + P F+ ++S + F+
Sbjct: 5380 L----KFVAADAGEYQCR-VTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQA 5434
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
T+K ++P ++ W +D + E + E V L + +E ++ C A ND
Sbjct: 5435 TLKGSLP--ITVTWLKDSDEITEDDNIRM-TFENNVASLYLSGIEVKHDGKYVCQAKNDA 5491
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELK 334
G S L + P + E + ++ L+ K G + KW+KDG+EL
Sbjct: 5492 GIQRCSALLSVKEPATITE----EAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELT 5547
Query: 335 PGDIHRI 341
G ++I
Sbjct: 5548 LGSKYKI 5554
Score = 51.6 bits (118), Expect = 4e-05
Identities = 53/230 (23%), Positives = 94/230 (40%), Gaps = 13/230 (5%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V +C++ G P + W KD ++++ +++T + S + +AS E
Sbjct: 7402 VILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNL----EASDVGEYHC 7457
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD-D 232
+ N++ + + P+FV L I + V S++W +D
Sbjct: 7458 K-ATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRG 7516
Query: 233 QPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP-RHY 291
+ + ES + + + L + + E + ++ C ND G S L ++ P R
Sbjct: 7517 EVIRESENTRISFIDN-IATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARII 7575
Query: 292 KKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+KP E + + A LEC V G P+ KW+KDG EL H I
Sbjct: 7576 EKP---EPMTVTTGNPFA--LECVVTGTPELSAKWFKDGRELSADSKHHI 7620
Score = 50.8 bits (116), Expect = 8e-05
Identities = 53/224 (23%), Positives = 97/224 (43%), Gaps = 21/224 (9%)
Query: 96 RKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---TGTNSL 151
+ P F ++L V EG V C V G + W K G+E+KP D +GT L
Sbjct: 9271 KPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVL 9330
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL 201
G Y C A N G ++ +++T++D +K + + FV
Sbjct: 9331 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGR---LFFVSEP 9387
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDD-QPVDESSRCHLGKEERGVFFLDIQALEF 260
+S+ F KV P P++ W + + +++ R + ++ L+I+
Sbjct: 9388 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFI-HQKGDEAKLEIRDTTK 9446
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAIL 304
D ++CVAFN+ G+ ++ + L + K+ + +L+A+L
Sbjct: 9447 TDSGLYRCVAFNEHGEIESN--VNLQVDERKKQEKIEGDLRAML 9488
Score = 50.0 bits (114), Expect = 1e-04
Identities = 54/217 (24%), Positives = 91/217 (41%), Gaps = 20/217 (9%)
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
SS+E E++ + +E F K P +H V+ +E + +I +
Sbjct: 4262 SSSESGTEEVAT-VKIQEAEGGFIKEDGP-MIH-TPLVDTVSEEGDIVHLTTSITNAKEV 4318
Query: 227 LWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLD-QAEWKCVAFNDFGQSVTSCFL 283
WY +++ P DE +C +++ + L I + D Q E+ C A ND G++ TS L
Sbjct: 4319 NWYFENKLVPSDEKFKC---LQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4375
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
++ R +E L+ L C++ P +W+K G E+ D I S
Sbjct: 4376 TVVKRAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS 4433
Query: 344 G---------QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC+ASN G + +A+L
Sbjct: 4434 SKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 4470
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/91 (32%), Positives = 51/91 (56%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQLTG 147
P F++ LQ++ +G V + +V G PTPV+ +++DG E++ GD+Y L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVE 174
+ G+Y A N +G+A+S+AEL V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 48.4 bits (110), Expect = 4e-04
Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 15/79 (18%)
Query: 111 EGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TGTNSL----------GSYC 155
EG+ V+F CK+ G+P P ++W+KDG+ +K G+ YQ+ G SL G Y
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1363
Query: 156 CIAKNCMGQASSSAELTVE 174
A N G A S +L VE
Sbjct: 1364 AFASNIKGNAICSGKLYVE 1382
Score = 47.6 bits (108), Expect = 7e-04
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P V GLK+V E ++ P P++ WYR+D ++ S + + G+ L
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQI-TFQSGIARLM 1001
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
I+ D + C A N+ G TSC+L + + ++K
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 1040
Score = 46.8 bits (106), Expect = 0.001
Identities = 54/230 (23%), Positives = 105/230 (45%), Gaps = 21/230 (9%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+F+C++ PV W+ G++L+P D ++ + + ++ + + +LT +
Sbjct: 13141 TFDCELSYEDIPV-EWYLKGKKLEPSD--KVVPRSEGKVHTLTLRDVKLEDAGEVQLTAK 13197
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLL-WYRDDQ 233
D + N LF K +F L+ + ++E ++ + E + + W+++
Sbjct: 13198 DFKTHAN------LFVKEPPVEFTKPLE--DQTVEEGATAVLECEVSRENAKVKWFKNGT 13249
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ +S + + + R V L I D + C A DF TSC L ++P H +
Sbjct: 13250 EILKSKKYEIVADGR-VRKLVIHDCTPEDIKTYTCDA-KDFK---TSCNLN-VVPPHVEF 13303
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
R L +LQ + ++ EC+ + +KW+KDG E+K G + IIS
Sbjct: 13304 LRPLTDLQ--VREKEMARFECE-LSRENAKVKWFKDGAEIKKGKKYDIIS 13350
Score = 45.6 bits (103), Expect = 0.003
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 15/91 (16%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL------TGT-- 148
P F++ L+ + +GL + FE VVG P P ++WFK+ ++L Y + +GT
Sbjct: 3621 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3680
Query: 149 ------NSLGSYCCIAKNCMGQASSSAELTV 173
G Y C A+N +G+++ +AEL V
Sbjct: 3681 VNDPQREDSGLYICKAENMLGESTCAAELLV 3711
Score = 45.6 bits (103), Expect = 0.003
Identities = 54/226 (23%), Positives = 100/226 (44%), Gaps = 19/226 (8%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSA 169
E+ FEC+V P W K QE+ D ++L + + + K+ + +
Sbjct: 12780 EKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGT--KHSMVIKSAAFEDEAKY 12836
Query: 170 ELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWY 229
ED + +L + KF+ LK V AK E FT++++ + W+
Sbjct: 12837 MFEAED------KHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELS-HDNIRVKWF 12889
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
++DQ + ++R ++E + + L D ++ + A G S + L ++
Sbjct: 12890 KNDQRL-HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAM---GMS-SEAKLTVLEGD 12944
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
Y + L++ + DE V L+C++ PV KW+KDG+E+KP
Sbjct: 12945 PYFTGK-LQDYTGVEKDE--VILQCEISKADAPV-KWFKDGKEIKP 12986
Score = 45.2 bits (102), Expect = 0.004
Identities = 47/211 (22%), Positives = 85/211 (40%), Gaps = 23/211 (10%)
Query: 98 PRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQL-- 145
P F++ + A ++ + + V+G P P + WF +G L P GD + L
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTV-------EDIQNQLNEEEKLQLFSKNQAPK 196
T G Y C+A N G+ SA L + +D + + + L+ P
Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3622
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
F+ LK + P F V P P++ W+++++ + S + G +
Sbjct: 3623 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3682
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + C A N G+S +C +L++
Sbjct: 3683 DPQREDSGLYICKAENMLGES--TCAAELLV 3711
Score = 42.7 bits (96), Expect = 0.020
Identities = 56/221 (25%), Positives = 90/221 (40%), Gaps = 43/221 (19%)
Query: 96 RKPRFMENLQAV-LTEEGLVSFECKV--VGFPTPVLSWFKDGQELKPGD----------- 141
+KP F + L ++ L G FEC++ +G PT V+ W DG+ L+ +
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1760
Query: 142 --VYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEE------------EKLQ 187
Y + + G C A N G +SA L V+D ++ + E E+L+
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELE 1820
Query: 188 LFS-------------KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + Q P V + V E RF +V P+P + WY + Q
Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1880
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ +S R + + G+ +LDI + D E K A N G
Sbjct: 1881 IRKSKRFRVRYD--GIHYLDIVDCKSYDTGEVKVTAENPEG 1919
Score = 40.3 bits (90), Expect = 0.11
Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 14/94 (14%)
Query: 292 KKPRFLENLQAI-LSDEGAVNLECKV--IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT 348
+KP F + L ++ L G + EC++ IG P V++W DG+ L+ + R+I+ + G
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN-EFGY 1759
Query: 349 CSL----------GTYTCEASNCMGVAASSASLL 372
CSL G TC A+N G +SA+L+
Sbjct: 1760 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1793
Score = 38.3 bits (85), Expect = 0.43
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P + L+ V EG V+ EC + G+P+P ++W+++ +++ +Q+T + +
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 152 --------GSYCCIAKNCMGQASSSAELTVE 174
G + C A N G S+S L V+
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Score = 38.3 bits (85), Expect = 0.43
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
IAKN G S ++ T + +++++L + PKF ++ E FR
Sbjct: 24523 IAKNAAGAISKPSDST-----GPITAKDEVELPRISMDPKF---RDTIVVNAGETFRLEA 24574
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHL 243
V P P++ W R D+ ++ES+RC +
Sbjct: 24575 DVHGKPLPTIEWLRGDKEIEESARCEI 24601
Score = 37.9 bits (84), Expect = 0.57
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P + L+ + EG +V LEC + G P P + WY++ +++ I I+ Q G L
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITFQSGIARLM 1001
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G +TC A N G ++S L
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYL 1030
Score = 37.9 bits (84), Expect = 0.57
Identities = 35/160 (21%), Positives = 70/160 (43%), Gaps = 12/160 (7%)
Query: 90 TVPKNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT 148
T K +KP + + V EG + F C+V G+P P ++W+ +GQ ++ +++
Sbjct: 1833 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD 1892
Query: 149 NSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G + +C + ++T E+ + + + KL++ + +SV +
Sbjct: 1893 ---GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED-------FRSVLRRA 1942
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
EP R V P + + D+PVD + + K +R
Sbjct: 1943 PEP-RPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKR 1981
Score = 36.7 bits (81), Expect = 1.3
Identities = 40/188 (21%), Positives = 80/188 (42%), Gaps = 24/188 (12%)
Query: 164 QASSSAELTVEDIQNQLNEEEKL--------QLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
Q + L +E+I+ +E++ Q S+ + + +++ D F
Sbjct: 9544 QEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFE 9603
Query: 216 IKVAIP-PEPSLLWYRDDQPVDESSRCHLGKE-ERGVFFLDIQALEFLDQAEWKCVAFND 273
I + I PE L WY+ + ++ S + + + +R L ++ + DQ ++ V
Sbjct: 9604 IDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHT--LRVKNCQLKDQGNYRLVC--- 9658
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEE 332
G + S L +I +P + +LQ + EG + C+ VP +W+++G
Sbjct: 9659 -GPHIASAKLTVI------EPAWERHLQDVTLKEGQTCTMTCQ-FSVPNVKSEWFRNGRI 9710
Query: 333 LKPGDIHR 340
LKP H+
Sbjct: 9711 LKPQGRHK 9718
Score = 36.3 bits (80), Expect = 1.7
Identities = 41/148 (27%), Positives = 62/148 (41%), Gaps = 13/148 (8%)
Query: 238 SSRCHLGKEERGVFFLDIQAL-EFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
S+ C+L + F + A+ E E + V D + TS + P P F
Sbjct: 1025 STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1084
Query: 297 LEN-LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL--- 351
+ + L + G+V C+V G P+P + W K G L G +++ + Q G C L
Sbjct: 1085 ITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVIS 1144
Query: 352 -------GTYTCEASNCMGVAASSASLL 372
G YT N G ++SASLL
Sbjct: 1145 MTFADDAGEYTIVVRNKHGETSASASLL 1172
Score = 36.3 bits (80), Expect = 1.7
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V F + G P P W DG E+K + Y + T++ S I KNC+ + + ++TV
Sbjct: 18455 VRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE-TDNFSSVLTI-KNCLRRDTGEYQITV 18512
Query: 174 ED 175
+
Sbjct: 18513 SN 18514
Score = 35.1 bits (77), Expect = 4.0
Identities = 59/259 (22%), Positives = 106/259 (40%), Gaps = 30/259 (11%)
Query: 90 TVPKNYRKPRFMENLQAV----LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
T K KPR + LQ + + E +V E KV + W KDGQE++P D +
Sbjct: 2345 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHI 2403
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
S+ + ++ + + + T+ + L+ ++ ++S + + LK V
Sbjct: 2404 VIDKQ--SHMLLIEDMTKEDAGNYSFTIPAL--GLSTSGRVSVYSVD----VITPLKDVN 2455
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL---GKEERGVFFLDIQALEFLD 262
KV++P S+ WY +D+ + R G ++R L I D
Sbjct: 2456 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQR----LVINRTHASD 2511
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQP 322
+ +K + G+ T+C L + K R L +L + +E G+
Sbjct: 2512 EGPYKLIV----GRVETNCNLSV---EKIKIIRGLRDLTCTETQNVVFEVELSHSGI--D 2562
Query: 323 VLKWYKDGEELKPGDIHRI 341
VL +KD +E+KP ++I
Sbjct: 2563 VLWNFKD-KEIKPSSKYKI 2580
Score = 35.1 bits (77), Expect = 4.0
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 22/228 (9%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC+V P W +DG+ L TN++ S K + A++ + E
Sbjct: 2639 FECEVAN-PDSKGEWLRDGKHLPL--------TNNIRSESDGHKRRLIIAATKLDDIGEY 2689
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+ +L K +A K LK++ + FT+++ P + W ++ V
Sbjct: 2690 TYKVATSKTSAKL--KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV-V 2746
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
ES+ + + ++ L I+ +D++ + F G+ S L + + KKP+
Sbjct: 2747 LESNEKYAISVKGTIYSLRIKNCAIVDESVY---GFR-LGRLGASARLHVETVKIIKKPK 2802
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
+ L+ V E V PV KW+ E+KP D HR++S
Sbjct: 2803 DVTALE-----NATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVS 2844
Score = 34.7 bits (76), Expect = 5.3
Identities = 79/377 (20%), Positives = 155/377 (41%), Gaps = 36/377 (9%)
Query: 2695 NIPQRD-----LAENEQQLGEDTTGSKQKVV-ELPDTIDDVSQDMIVEHLPTSEVKL-LE 2747
N PQR+ + + E LGE T ++ V+ E D D + P + L+
Sbjct: 3682 NDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLK 3741
Query: 2748 GQLLAA--EENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKSKLVEELQTIA 2805
G + A E ++ +K +++ TE ++ + IA E+ S+L Q +
Sbjct: 3742 GPAVEALDSEQEIATFVKDTILKAALITE---ENQQLSYEHIAKANELSSQLPLGAQELQ 3798
Query: 2806 DSKSQKMIEESTTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESITELNQKSSDF 2865
Q + +TRE L G P S N+ Q +++ ++ +
Sbjct: 3799 SILEQDKLTPESTREF----LCINGSIHFQPLKEPSPNLQLQIVQSQKTFSKEGILMPEE 3854
Query: 2866 TKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHETIQTLNSNLE 2925
++Q+++SD +++I + ++I + L E N P + + + +++
Sbjct: 3855 PETQAVLSD-TEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSSIEPPMHSYLTSVA 3913
Query: 2926 NEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKKDQAESSNSQTA--ENIVR 2983
E+ E+ VS E V Q+ ++ L ++S+ L + ES S +
Sbjct: 3914 EEVLSPK--EKTVSDTNREQRVTLQKQEAQSAL-ILSQSLAEGHVESLQSPDVMISQVNY 3970
Query: 2984 EIVVTSEITALETLGL------PLERSGNDGDL-VEL-------LSIETKQITVEPRATT 3029
E +V SE + E + PLE +G D + +E L++E KQ+ ++ +
Sbjct: 3971 EPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEKQVLLKEEHSD 4030
Query: 3030 YEVVAEQQVVPSGQQPV 3046
V+ Q++ S ++PV
Sbjct: 4031 NVVMPPDQIIESKREPV 4047
Score = 34.7 bits (76), Expect = 5.3
Identities = 12/29 (41%), Positives = 20/29 (68%)
Query: 120 VVGFPTPVLSWFKDGQELKPGDVYQLTGT 148
++G P P SW K G++++P D+ Q+T T
Sbjct: 21330 ILGKPLPKSSWSKAGKDIRPSDITQITST 21358
Score = 34.3 bits (75), Expect = 7.0
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 9/72 (12%)
Query: 310 VNLECKVIGVPQPVLKWYKDGEELKPGD--------IHRIISGQDGT-CSLGTYTCEASN 360
+ +E VIG P+P + W KDGE LK ++ ++G G YT A+N
Sbjct: 25256 LKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATN 25315
Query: 361 CMGVAASSASLL 372
G A + S++
Sbjct: 25316 SAGTATENLSVI 25327
Score = 33.9 bits (74), Expect = 9.3
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 9/72 (12%)
Query: 303 ILSDEGAVNLECKVIGVPQPVLKWYKDGEEL--------KPGDIHRIISGQDGT-CSLGT 353
IL A LE V G P P ++W KDG+EL K D + +D T G
Sbjct: 22399 ILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGA 22458
Query: 354 YTCEASNCMGVA 365
YT A+N G A
Sbjct: 22459 YTLTATNPGGFA 22470
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 98.3 bits (234), Expect = 4e-19
Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 16/241 (6%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK------PGDVYQLTGTNSL----GSYC 155
AV+ + V +C V G P P ++W +GQ ++ V +L ++L G+Y
Sbjct: 524 AVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYT 582
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF-SKNQAPKFVHGLKSVEAKIDEPFRF 214
C+A+N +GQ S SA +TV + ++ E L + SK AP F+ GL ++
Sbjct: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFND 273
T++V+ P P ++W + + ES H E+RG L IQ + D + C A+N
Sbjct: 643 TVQVSGNPPPEVIWLHNGNEIQESEDFHF--EQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEE 332
G+ T L + P +P F+ +++ + G +V + C + G P P + W +DG+
Sbjct: 701 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 760
Query: 333 L 333
L
Sbjct: 761 L 761
Score = 76.6 bits (180), Expect = 1e-12
Identities = 90/314 (28%), Positives = 124/314 (39%), Gaps = 57/314 (18%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPG----DVYQLTGTNSL- 151
P+F Q+ +E V F C+V G P P ++WF +G ++ +VY+ G++ L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLC 473
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G+Y C A N GQ S S L VE +L AP F LK
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVE------------RLAVMEVAPSFSSVLK 521
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES-SRCHLGKEERGVFFLDIQALEFL 261
+ F V P P + W + QP+ + S C E GV L IQ
Sbjct: 522 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPE 576
Query: 262 DQAEWKCVAFNDFGQ--------------SVTSCFLKLIIPRHYKKPRFLENLQAI-LSD 306
D + C+A N GQ S S +L + P P FL+ L + + D
Sbjct: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISG-QDGTC-------SLGTYTCE 357
V + +V G P P + W +G E++ D H G Q C GTYTCE
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
Query: 358 ASNCMGVAASSASL 371
A N G + A L
Sbjct: 697 AWNSAGEVRTQAVL 710
Score = 59.3 bits (137), Expect = 2e-07
Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 32/219 (14%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL- 151
P F+ + + +EG + FE +V G+P P ++W ++GQ + G + L GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVE-DIQNQLNEEEKLQL----FSKNQA--- 194
G Y C A N G + ELTVE QL + + FS +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152
Query: 195 --------PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE 246
PKF L V K + RF+ K+ P+P + W + + P+ S+R + E
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV-SE 211
Query: 247 ERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ G+ L+I + D + C+ N G++ S L +
Sbjct: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 1790 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1849
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 1850 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898
Score = 54.0 bits (124), Expect = 8e-06
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 14/126 (11%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG-----------DVYQL 145
P+F L V+ +EG + F CK+ G P P ++W K L+P V ++
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 146 TGTNS--LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G N +G Y C+ N G+AS SAEL+++ + + + + + K V + S
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 204 VEAKID 209
E+K+D
Sbjct: 281 KESKLD 286
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1911
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 1899
Score = 45.2 bits (102), Expect = 0.004
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP F+ +++ K +F +V PEP + W+R+ QP+ R L RG F
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 253 LDIQALEFLDQAEWKCVAFNDFG 275
L I A+ D+ ++ C A N G
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSG 113
Score = 44.0 bits (99), Expect = 0.009
Identities = 47/213 (22%), Positives = 91/213 (42%), Gaps = 29/213 (13%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT- 146
P P P F++ L + +G V+ +V G P P + W +G E++ + +
Sbjct: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
Query: 147 -GT-NSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA 194
GT +SL G+Y C A N G+ + A LTV++ +
Sbjct: 674 RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD-------------GTQ 720
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F+ +SV A + + + +A P P++ W RD + + + + + VF L
Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
++ ++ +++ + N G+ SC + L++
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGE--CSCQVSLML 811
Score = 44.0 bits (99), Expect = 0.009
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F + LQ V EG + +C+V P + W +G+ LK L+ SL
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEE--EKLQLFSKNQAPKFVHGL 201
G Y C+AKN GQA S ++TV+D N + E K+ P +
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
K + K A+PP+ ++ + +DQ V
Sbjct: 1218 SDATVKKKPAPKTPPKAAMPPQ--IIQFPEDQKV 1249
Score = 38.3 bits (85), Expect = 0.43
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 294 PRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P F+ + + EGA E +V G P+P + W+++G+ + G + G GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTCEA+N G + L
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVEL 121
Score = 37.5 bits (83), Expect = 0.75
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P+F L ++ EG + CK+ G PQP + W K L+P +S ++G L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SARVSVSEKNGMQVLE 219
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTC N G A+ SA L
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Score = 36.3 bits (80), Expect = 1.7
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Query: 166 SSSAELTVEDIQNQLN--------EEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
S+S E +D++N +N + + + S+ AP F L+ V + +
Sbjct: 1061 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ P +++W + + + ++++ + +E + + I+ D+ +KCVA ND GQ+
Sbjct: 1121 VSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 1179
Query: 278 VTSC 281
SC
Sbjct: 1180 ECSC 1183
>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
polypeptide kinase isoform 2 protein.
Length = 1845
Score = 98.3 bits (234), Expect = 4e-19
Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 16/241 (6%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK------PGDVYQLTGTNSL----GSYC 155
AV+ + V +C V G P P ++W +GQ ++ V +L ++L G+Y
Sbjct: 455 AVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYT 513
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF-SKNQAPKFVHGLKSVEAKIDEPFRF 214
C+A+N +GQ S SA +TV + ++ E L + SK AP F+ GL ++
Sbjct: 514 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 573
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFND 273
T++V+ P P ++W + + ES H E+RG L IQ + D + C A+N
Sbjct: 574 TVQVSGNPPPEVIWLHNGNEIQESEDFHF--EQRGTQHSLCIQEVFPEDTGTYTCEAWNS 631
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEE 332
G+ T L + P +P F+ +++ + G +V + C + G P P + W +DG+
Sbjct: 632 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 691
Query: 333 L 333
L
Sbjct: 692 L 692
Score = 59.3 bits (137), Expect = 2e-07
Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 32/219 (14%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL- 151
P F+ + + +EG + FE +V G+P P ++W ++GQ + G + L GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVE-DIQNQLNEEEKLQL----FSKNQA--- 194
G Y C A N G + ELTVE QL + + FS +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152
Query: 195 --------PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE 246
PKF L V K + RF+ K+ P+P + W + + P+ S+R + E
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV-SE 211
Query: 247 ERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ G+ L+I + D + C+ N G++ S L +
Sbjct: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 1721 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1780
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 1781 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1829
Score = 54.0 bits (124), Expect = 8e-06
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 14/126 (11%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG-----------DVYQL 145
P+F L V+ +EG + F CK+ G P P ++W K L+P V ++
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 146 TGTNS--LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G N +G Y C+ N G+AS SAEL+++ + + + + + K V + S
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 204 VEAKID 209
E+K+D
Sbjct: 281 KESKLD 286
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 1735 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1794
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 1795 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1842
Score = 50.8 bits (116), Expect = 8e-05
Identities = 59/203 (29%), Positives = 78/203 (38%), Gaps = 30/203 (14%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES-SRCHLGKEERGVFF 252
AP F LK + F V P P + W + QP+ + S C E GV
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAE 498
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ--------------SVTSCFLKLIIPRHYKKPRFLE 298
L IQ D + C+A N GQ S S +L + P P FL+
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
Query: 299 NLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISG-QDGTC------ 349
L + + D V + +V G P P + W +G E++ D H G Q C
Sbjct: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
Query: 350 -SLGTYTCEASNCMGVAASSASL 371
GTYTCEA N G + A L
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVL 641
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 1830
Score = 45.2 bits (102), Expect = 0.004
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP F+ +++ K +F +V PEP + W+R+ QP+ R L RG F
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 253 LDIQALEFLDQAEWKCVAFNDFG 275
L I A+ D+ ++ C A N G
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSG 113
Score = 44.0 bits (99), Expect = 0.009
Identities = 47/213 (22%), Positives = 91/213 (42%), Gaps = 29/213 (13%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT- 146
P P P F++ L + +G V+ +V G P P + W +G E++ + +
Sbjct: 545 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 604
Query: 147 -GT-NSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA 194
GT +SL G+Y C A N G+ + A LTV++ +
Sbjct: 605 RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD-------------GTQ 651
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F+ +SV A + + + +A P P++ W RD + + + + + VF L
Sbjct: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
++ ++ +++ + N G+ SC + L++
Sbjct: 712 LKKVQPWHAGQYEILLKNRVGE--CSCQVSLML 742
Score = 44.0 bits (99), Expect = 0.009
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F + LQ V EG + +C+V P + W +G+ LK L+ SL
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEE--EKLQLFSKNQAPKFVHGL 201
G Y C+AKN GQA S ++TV+D N + E K+ P +
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
K + K A+PP+ ++ + +DQ V
Sbjct: 1149 SDATVKKKPAPKTPPKAAMPPQ--IIQFPEDQKV 1180
Score = 38.3 bits (85), Expect = 0.43
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 294 PRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P F+ + + EGA E +V G P+P + W+++G+ + G + G GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTCEA+N G + L
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVEL 121
Score = 37.5 bits (83), Expect = 0.75
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P+F L ++ EG + CK+ G PQP + W K L+P +S ++G L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SARVSVSEKNGMQVLE 219
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTC N G A+ SA L
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Score = 36.3 bits (80), Expect = 1.7
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Query: 166 SSSAELTVEDIQNQLN--------EEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
S+S E +D++N +N + + + S+ AP F L+ V + +
Sbjct: 992 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1051
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ P +++W + + + ++++ + +E + + I+ D+ +KCVA ND GQ+
Sbjct: 1052 VSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 1110
Query: 278 VTSC 281
SC
Sbjct: 1111 ECSC 1114
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 98.3 bits (234), Expect = 4e-19
Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 16/241 (6%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK------PGDVYQLTGTNSL----GSYC 155
AV+ + V +C V G P P ++W +GQ ++ V +L ++L G+Y
Sbjct: 524 AVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYT 582
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF-SKNQAPKFVHGLKSVEAKIDEPFRF 214
C+A+N +GQ S SA +TV + ++ E L + SK AP F+ GL ++
Sbjct: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFND 273
T++V+ P P ++W + + ES H E+RG L IQ + D + C A+N
Sbjct: 643 TVQVSGNPPPEVIWLHNGNEIQESEDFHF--EQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEE 332
G+ T L + P +P F+ +++ + G +V + C + G P P + W +DG+
Sbjct: 701 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 760
Query: 333 L 333
L
Sbjct: 761 L 761
Score = 76.2 bits (179), Expect = 2e-12
Identities = 90/314 (28%), Positives = 124/314 (39%), Gaps = 57/314 (18%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPG----DVYQLTGTNSL- 151
P+F Q+ +E V F C+V G P P ++WF +G ++ +VY+ G++ L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G+Y C A N GQ S S L VE +L AP F LK
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVE------------RLAVMEVAPSFSSVLK 521
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES-SRCHLGKEERGVFFLDIQALEFL 261
+ F V P P + W + QP+ + S C E GV L IQ
Sbjct: 522 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPE 576
Query: 262 DQAEWKCVAFNDFGQ--------------SVTSCFLKLIIPRHYKKPRFLENLQAI-LSD 306
D + C+A N GQ S S +L + P P FL+ L + + D
Sbjct: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISG-QDGTC-------SLGTYTCE 357
V + +V G P P + W +G E++ D H G Q C GTYTCE
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
Query: 358 ASNCMGVAASSASL 371
A N G + A L
Sbjct: 697 AWNSAGEVRTQAVL 710
Score = 59.3 bits (137), Expect = 2e-07
Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 32/219 (14%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL- 151
P F+ + + +EG + FE +V G+P P ++W ++GQ + G + L GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVE-DIQNQLNEEEKLQL----FSKNQA--- 194
G Y C A N G + ELTVE QL + + FS +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152
Query: 195 --------PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE 246
PKF L V K + RF+ K+ P+P + W + + P+ S+R + E
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV-SE 211
Query: 247 ERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ G+ L+I + D + C+ N G++ S L +
Sbjct: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 1790 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1849
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 1850 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898
Score = 54.0 bits (124), Expect = 8e-06
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 14/126 (11%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG-----------DVYQL 145
P+F L V+ +EG + F CK+ G P P ++W K L+P V ++
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 146 TGTNS--LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G N +G Y C+ N G+AS SAEL+++ + + + + + K V + S
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 204 VEAKID 209
E+K+D
Sbjct: 281 KESKLD 286
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1911
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 1899
Score = 45.2 bits (102), Expect = 0.004
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP F+ +++ K +F +V PEP + W+R+ QP+ R L RG F
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 253 LDIQALEFLDQAEWKCVAFNDFG 275
L I A+ D+ ++ C A N G
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSG 113
Score = 44.0 bits (99), Expect = 0.009
Identities = 47/213 (22%), Positives = 91/213 (42%), Gaps = 29/213 (13%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT- 146
P P P F++ L + +G V+ +V G P P + W +G E++ + +
Sbjct: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
Query: 147 -GT-NSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA 194
GT +SL G+Y C A N G+ + A LTV++ +
Sbjct: 674 RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD-------------GTQ 720
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F+ +SV A + + + +A P P++ W RD + + + + + VF L
Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
++ ++ +++ + N G+ SC + L++
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGE--CSCQVSLML 811
Score = 44.0 bits (99), Expect = 0.009
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F + LQ V EG + +C+V P + W +G+ LK L+ SL
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEE--EKLQLFSKNQAPKFVHGL 201
G Y C+AKN GQA S ++TV+D N + E K+ P +
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
K + K A+PP+ ++ + +DQ V
Sbjct: 1218 SDATVKKKPAPKTPPKAAMPPQ--IIQFPEDQKV 1249
Score = 38.3 bits (85), Expect = 0.43
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 294 PRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P F+ + + EGA E +V G P+P + W+++G+ + G + G GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTCEA+N G + L
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVEL 121
Score = 37.5 bits (83), Expect = 0.75
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P+F L ++ EG + CK+ G PQP + W K L+P +S ++G L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SARVSVSEKNGMQVLE 219
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTC N G A+ SA L
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Score = 36.3 bits (80), Expect = 1.7
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Query: 166 SSSAELTVEDIQNQLN--------EEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
S+S E +D++N +N + + + S+ AP F L+ V + +
Sbjct: 1061 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ P +++W + + + ++++ + +E + + I+ D+ +KCVA ND GQ+
Sbjct: 1121 VSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 1179
Query: 278 VTSC 281
SC
Sbjct: 1180 ECSC 1183
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 97.9 bits (233), Expect = 5e-19
Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 16/241 (6%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK------PGDVYQLTGTNSL----GSYC 155
AV+ + V +C V G P P ++W +GQ ++ V +L ++L G+Y
Sbjct: 524 AVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYT 582
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF-SKNQAPKFVHGLKSVEAKIDEPFRF 214
C+A+N +GQ S SA +TV + ++ E L + SK AP F+ GL ++
Sbjct: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFND 273
T++V+ P P ++W + + ES H E+RG L IQ + D + C A+N
Sbjct: 643 TVQVSGNPPPEVIWLHNGNEIQESEDFHF--EQRGTQHSLWIQEVFPEDTGTYTCEAWNS 700
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEE 332
G+ T L + P +P F+ +++ + G +V + C + G P P + W +DG+
Sbjct: 701 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 760
Query: 333 L 333
L
Sbjct: 761 L 761
Score = 73.7 bits (173), Expect = 9e-12
Identities = 88/314 (28%), Positives = 123/314 (39%), Gaps = 57/314 (18%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPG----DVYQLTGTNSL- 151
P+F Q+ +E V F C+V G P P ++WF +G ++ +VY+ G++ L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G+Y C A N GQ S S L VE +L AP F LK
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVE------------RLAVMEVAPSFSSVLK 521
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES-SRCHLGKEERGVFFLDIQALEFL 261
+ F V P P + W + QP+ + S C E GV L IQ
Sbjct: 522 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPE 576
Query: 262 DQAEWKCVAFNDFGQ--------------SVTSCFLKLIIPRHYKKPRFLENLQAI-LSD 306
D + C+A N GQ S S +L + P P FL+ L + + D
Sbjct: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQDGTC--------SLGTYTCE 357
V + +V G P P + W +G E++ D H G + GTYTCE
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCE 696
Query: 358 ASNCMGVAASSASL 371
A N G + A L
Sbjct: 697 AWNSAGEVRTQAVL 710
Score = 59.3 bits (137), Expect = 2e-07
Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 32/219 (14%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL- 151
P F+ + + +EG + FE +V G+P P ++W ++GQ + G + L GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVE-DIQNQLNEEEKLQL----FSKNQA--- 194
G Y C A N G + ELTVE QL + + FS +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152
Query: 195 --------PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE 246
PKF L V K + RF+ K+ P+P + W + + P+ S+R + E
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV-SE 211
Query: 247 ERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ G+ L+I + D + C+ N G++ S L +
Sbjct: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 1790 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1849
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 1850 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1898
Score = 54.0 bits (124), Expect = 8e-06
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 14/126 (11%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG-----------DVYQL 145
P+F L V+ +EG + F CK+ G P P ++W K L+P V ++
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 146 TGTNS--LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G N +G Y C+ N G+AS SAEL+++ + + + + + K V + S
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 204 VEAKID 209
E+K+D
Sbjct: 281 KESKLD 286
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 1804 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1863
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 1864 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1911
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 1899
Score = 45.2 bits (102), Expect = 0.004
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP F+ +++ K +F +V PEP + W+R+ QP+ R L RG F
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 253 LDIQALEFLDQAEWKCVAFNDFG 275
L I A+ D+ ++ C A N G
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSG 113
Score = 44.0 bits (99), Expect = 0.009
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F + LQ V EG + +C+V P + W +G+ LK L+ SL
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEE--EKLQLFSKNQAPKFVHGL 201
G Y C+AKN GQA S ++TV+D N + E K+ P +
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
K + K A+PP+ ++ + +DQ V
Sbjct: 1218 SDATVKKKPAPKTPPKAAMPPQ--IIQFPEDQKV 1249
Score = 38.3 bits (85), Expect = 0.43
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 294 PRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P F+ + + EGA E +V G P+P + W+++G+ + G + G GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTCEA+N G + L
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVEL 121
Score = 37.5 bits (83), Expect = 0.75
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P+F L ++ EG + CK+ G PQP + W K L+P +S ++G L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SARVSVSEKNGMQVLE 219
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTC N G A+ SA L
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Score = 36.3 bits (80), Expect = 1.7
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Query: 166 SSSAELTVEDIQNQLN--------EEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
S+S E +D++N +N + + + S+ AP F L+ V + +
Sbjct: 1061 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ P +++W + + + ++++ + +E + + I+ D+ +KCVA ND GQ+
Sbjct: 1121 VSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 1179
Query: 278 VTSC 281
SC
Sbjct: 1180 ECSC 1183
>AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kinase
isoform 3B protein.
Length = 1793
Score = 97.9 bits (233), Expect = 5e-19
Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 16/241 (6%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK------PGDVYQLTGTNSL----GSYC 155
AV+ + V +C V G P P ++W +GQ ++ V +L ++L G+Y
Sbjct: 455 AVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYT 513
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF-SKNQAPKFVHGLKSVEAKIDEPFRF 214
C+A+N +GQ S SA +TV + ++ E L + SK AP F+ GL ++
Sbjct: 514 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 573
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFND 273
T++V+ P P ++W + + ES H E+RG L IQ + D + C A+N
Sbjct: 574 TVQVSGNPPPEVIWLHNGNEIQESEDFHF--EQRGTQHSLWIQEVFPEDTGTYTCEAWNS 631
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEE 332
G+ T L + P +P F+ +++ + G +V + C + G P P + W +DG+
Sbjct: 632 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 691
Query: 333 L 333
L
Sbjct: 692 L 692
Score = 59.3 bits (137), Expect = 2e-07
Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 32/219 (14%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL- 151
P F+ + + +EG + FE +V G+P P ++W ++GQ + G + L GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVE-DIQNQLNEEEKLQL----FSKNQA--- 194
G Y C A N G + ELTVE QL + + FS +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152
Query: 195 --------PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE 246
PKF L V K + RF+ K+ P+P + W + + P+ S+R + E
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV-SE 211
Query: 247 ERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ G+ L+I + D + C+ N G++ S L +
Sbjct: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 54.0 bits (124), Expect = 8e-06
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 14/126 (11%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG-----------DVYQL 145
P+F L V+ +EG + F CK+ G P P ++W K L+P V ++
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 146 TGTNS--LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G N +G Y C+ N G+AS SAEL+++ + + + + + K V + S
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 204 VEAKID 209
E+K+D
Sbjct: 281 KESKLD 286
Score = 52.0 bits (119), Expect = 3e-05
Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 12/106 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 1669 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1728
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSA 369
+ +I +DG CSL YTC+A N +G A +A
Sbjct: 1729 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1774
Score = 50.0 bits (114), Expect = 1e-04
Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 1683 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1742
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AE VE ++ E E+
Sbjct: 1743 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGEGEE 1790
Score = 48.4 bits (110), Expect = 4e-04
Identities = 57/203 (28%), Positives = 78/203 (38%), Gaps = 30/203 (14%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES-SRCHLGKEERGVFF 252
AP F LK + F V P P + W + QP+ + S C E GV
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAE 498
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ--------------SVTSCFLKLIIPRHYKKPRFLE 298
L IQ D + C+A N GQ S S +L + P P FL+
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
Query: 299 NLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQDGTCSL----- 351
L + + D V + +V G P P + W +G E++ D H G + +
Sbjct: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFP 618
Query: 352 ---GTYTCEASNCMGVAASSASL 371
GTYTCEA N G + A L
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVL 641
Score = 46.8 bits (106), Expect = 0.001
Identities = 24/83 (28%), Positives = 41/83 (49%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 1688 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1747
Query: 255 IQALEFLDQAEWKCVAFNDFGQS 277
I + D A++ C A N G++
Sbjct: 1748 ISDVCGDDDAKYTCKAVNSLGEA 1770
Score = 45.2 bits (102), Expect = 0.004
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP F+ +++ K +F +V PEP + W+R+ QP+ R L RG F
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 253 LDIQALEFLDQAEWKCVAFNDFG 275
L I A+ D+ ++ C A N G
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSG 113
Score = 44.0 bits (99), Expect = 0.009
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F + LQ V EG + +C+V P + W +G+ LK L+ SL
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEE--EKLQLFSKNQAPKFVHGL 201
G Y C+AKN GQA S ++TV+D N + E K+ P +
Sbjct: 1089 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
K + K A+PP+ ++ + +DQ V
Sbjct: 1149 SDATVKKKPAPKTPPKAAMPPQ--IIQFPEDQKV 1180
Score = 38.3 bits (85), Expect = 0.43
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 294 PRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P F+ + + EGA E +V G P+P + W+++G+ + G + G GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTCEA+N G + L
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVEL 121
Score = 37.9 bits (84), Expect = 0.57
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Query: 166 SSSAELTVEDIQNQLN--------EEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
S+S E +D++N +N + + + S+ AP F L+ V + +
Sbjct: 992 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1051
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ P +++W + + + ++++ + +E + + I+ D+ +KCVA ND GQ+
Sbjct: 1052 VSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQA 1110
Query: 278 VTSC 281
SC
Sbjct: 1111 ECSC 1114
Score = 37.5 bits (83), Expect = 0.75
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P+F L ++ EG + CK+ G PQP + W K L+P +S ++G L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SARVSVSEKNGMQVLE 219
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTC N G A+ SA L
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 97.9 bits (233), Expect = 5e-19
Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 16/241 (6%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK------PGDVYQLTGTNSL----GSYC 155
AV+ + V +C V G P P ++W +GQ ++ V +L ++L G+Y
Sbjct: 524 AVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYT 582
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF-SKNQAPKFVHGLKSVEAKIDEPFRF 214
C+A+N +GQ S SA +TV + ++ E L + SK AP F+ GL ++
Sbjct: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFND 273
T++V+ P P ++W + + ES H E+RG L IQ + D + C A+N
Sbjct: 643 TVQVSGNPPPEVIWLHNGNEIQESEDFHF--EQRGTQHSLWIQEVFPEDTGTYTCEAWNS 700
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEE 332
G+ T L + P +P F+ +++ + G +V + C + G P P + W +DG+
Sbjct: 701 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 760
Query: 333 L 333
L
Sbjct: 761 L 761
Score = 73.7 bits (173), Expect = 9e-12
Identities = 88/314 (28%), Positives = 123/314 (39%), Gaps = 57/314 (18%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPG----DVYQLTGTNSL- 151
P+F Q+ +E V F C+V G P P ++WF +G ++ +VY+ G++ L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G+Y C A N GQ S S L VE +L AP F LK
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVE------------RLAVMEVAPSFSSVLK 521
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES-SRCHLGKEERGVFFLDIQALEFL 261
+ F V P P + W + QP+ + S C E GV L IQ
Sbjct: 522 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPE 576
Query: 262 DQAEWKCVAFNDFGQ--------------SVTSCFLKLIIPRHYKKPRFLENLQAI-LSD 306
D + C+A N GQ S S +L + P P FL+ L + + D
Sbjct: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQDGTC--------SLGTYTCE 357
V + +V G P P + W +G E++ D H G + GTYTCE
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCE 696
Query: 358 ASNCMGVAASSASL 371
A N G + A L
Sbjct: 697 AWNSAGEVRTQAVL 710
Score = 59.3 bits (137), Expect = 2e-07
Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 32/219 (14%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL- 151
P F+ + + +EG + FE +V G+P P ++W ++GQ + G + L GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVE-DIQNQLNEEEKLQL----FSKNQA--- 194
G Y C A N G + ELTVE QL + + FS +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152
Query: 195 --------PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE 246
PKF L V K + RF+ K+ P+P + W + + P+ S+R + E
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV-SE 211
Query: 247 ERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ G+ L+I + D + C+ N G++ S L +
Sbjct: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 54.0 bits (124), Expect = 8e-06
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 14/126 (11%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG-----------DVYQL 145
P+F L V+ +EG + F CK+ G P P ++W K L+P V ++
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 146 TGTNS--LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G N +G Y C+ N G+AS SAEL+++ + + + + + K V + S
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 204 VEAKID 209
E+K+D
Sbjct: 281 KESKLD 286
Score = 52.0 bits (119), Expect = 3e-05
Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 12/106 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 1738 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1797
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSA 369
+ +I +DG CSL YTC+A N +G A +A
Sbjct: 1798 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1843
Score = 50.0 bits (114), Expect = 1e-04
Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 1752 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1811
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AE VE ++ E E+
Sbjct: 1812 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGEGEE 1859
Score = 46.8 bits (106), Expect = 0.001
Identities = 24/83 (28%), Positives = 41/83 (49%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 1757 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1816
Query: 255 IQALEFLDQAEWKCVAFNDFGQS 277
I + D A++ C A N G++
Sbjct: 1817 ISDVCGDDDAKYTCKAVNSLGEA 1839
Score = 45.2 bits (102), Expect = 0.004
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP F+ +++ K +F +V PEP + W+R+ QP+ R L RG F
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 253 LDIQALEFLDQAEWKCVAFNDFG 275
L I A+ D+ ++ C A N G
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSG 113
Score = 44.0 bits (99), Expect = 0.009
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F + LQ V EG + +C+V P + W +G+ LK L+ SL
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEE--EKLQLFSKNQAPKFVHGL 201
G Y C+AKN GQA S ++TV+D N + E K+ P +
Sbjct: 1158 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
K + K A+PP+ ++ + +DQ V
Sbjct: 1218 SDATVKKKPAPKTPPKAAMPPQ--IIQFPEDQKV 1249
Score = 38.3 bits (85), Expect = 0.43
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 294 PRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P F+ + + EGA E +V G P+P + W+++G+ + G + G GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTCEA+N G + L
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVEL 121
Score = 37.9 bits (84), Expect = 0.57
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Query: 166 SSSAELTVEDIQNQLN--------EEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
S+S E +D++N +N + + + S+ AP F L+ V + +
Sbjct: 1061 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ P +++W + + + ++++ + +E + + I+ D+ +KCVA ND GQ+
Sbjct: 1121 VSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQA 1179
Query: 278 VTSC 281
SC
Sbjct: 1180 ECSC 1183
Score = 37.5 bits (83), Expect = 0.75
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P+F L ++ EG + CK+ G PQP + W K L+P +S ++G L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SARVSVSEKNGMQVLE 219
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTC N G A+ SA L
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
isoform 2 protein.
Length = 1845
Score = 97.9 bits (233), Expect = 5e-19
Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 16/241 (6%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK------PGDVYQLTGTNSL----GSYC 155
AV+ + V +C V G P P ++W +GQ ++ V +L ++L G+Y
Sbjct: 455 AVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYT 513
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF-SKNQAPKFVHGLKSVEAKIDEPFRF 214
C+A+N +GQ S SA +TV + ++ E L + SK AP F+ GL ++
Sbjct: 514 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 573
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFND 273
T++V+ P P ++W + + ES H E+RG L IQ + D + C A+N
Sbjct: 574 TVQVSGNPPPEVIWLHNGNEIQESEDFHF--EQRGTQHSLWIQEVFPEDTGTYTCEAWNS 631
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEE 332
G+ T L + P +P F+ +++ + G +V + C + G P P + W +DG+
Sbjct: 632 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 691
Query: 333 L 333
L
Sbjct: 692 L 692
Score = 59.3 bits (137), Expect = 2e-07
Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 32/219 (14%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL- 151
P F+ + + +EG + FE +V G+P P ++W ++GQ + G + L GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVE-DIQNQLNEEEKLQL----FSKNQA--- 194
G Y C A N G + ELTVE QL + + FS +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETR 152
Query: 195 --------PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE 246
PKF L V K + RF+ K+ P+P + W + + P+ S+R + E
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV-SE 211
Query: 247 ERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ G+ L+I + D + C+ N G++ S L +
Sbjct: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 1721 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1780
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 1781 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1829
Score = 54.0 bits (124), Expect = 8e-06
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 14/126 (11%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG-----------DVYQL 145
P+F L V+ +EG + F CK+ G P P ++W K L+P V ++
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 146 TGTNS--LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G N +G Y C+ N G+AS SAEL+++ + + + + + K V + S
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
Query: 204 VEAKID 209
E+K+D
Sbjct: 281 KESKLD 286
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 1735 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1794
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 1795 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1842
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 1830
Score = 48.4 bits (110), Expect = 4e-04
Identities = 57/203 (28%), Positives = 78/203 (38%), Gaps = 30/203 (14%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES-SRCHLGKEERGVFF 252
AP F LK + F V P P + W + QP+ + S C E GV
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAE 498
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ--------------SVTSCFLKLIIPRHYKKPRFLE 298
L IQ D + C+A N GQ S S +L + P P FL+
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
Query: 299 NLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQDGTCSL----- 351
L + + D V + +V G P P + W +G E++ D H G + +
Sbjct: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFP 618
Query: 352 ---GTYTCEASNCMGVAASSASL 371
GTYTCEA N G + A L
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVL 641
Score = 45.2 bits (102), Expect = 0.004
Identities = 26/83 (31%), Positives = 41/83 (49%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP F+ +++ K +F +V PEP + W+R+ QP+ R L RG F
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 253 LDIQALEFLDQAEWKCVAFNDFG 275
L I A+ D+ ++ C A N G
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSG 113
Score = 44.0 bits (99), Expect = 0.009
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F + LQ V EG + +C+V P + W +G+ LK L+ SL
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEE--EKLQLFSKNQAPKFVHGL 201
G Y C+AKN GQA S ++TV+D N + E K+ P +
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
K + K A+PP+ ++ + +DQ V
Sbjct: 1149 SDATVKKKPAPKTPPKAAMPPQ--IIQFPEDQKV 1180
Score = 38.3 bits (85), Expect = 0.43
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 294 PRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P F+ + + EGA E +V G P+P + W+++G+ + G + G GT SL
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTCEA+N G + L
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVEL 121
Score = 37.5 bits (83), Expect = 0.75
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P+F L ++ EG + CK+ G PQP + W K L+P +S ++G L
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SARVSVSEKNGMQVLE 219
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YTC N G A+ SA L
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Score = 36.3 bits (80), Expect = 1.7
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Query: 166 SSSAELTVEDIQNQLN--------EEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
S+S E +D++N +N + + + S+ AP F L+ V + +
Sbjct: 992 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1051
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ P +++W + + + ++++ + +E + + I+ D+ +KCVA ND GQ+
Sbjct: 1052 VSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 1110
Query: 278 VTSC 281
SC
Sbjct: 1111 ECSC 1114
>BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein.
Length = 510
Score = 93.5 bits (222), Expect = 1e-17
Identities = 94/329 (28%), Positives = 141/329 (42%), Gaps = 51/329 (15%)
Query: 93 KNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP-GDVY----QLT 146
+N P F L+ EG+ V+F C+V G P P + WFKDG+++ P D Y L
Sbjct: 123 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLD 182
Query: 147 GTNSL----------GSYCCIAKNCMGQASSSAELTVEDI-------------------- 176
GT SL G+Y +A N G+ S + L V+ +
Sbjct: 183 GTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPR 242
Query: 177 -QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+++ + +E + + P F+ + + + R KV+ P P L W D +PV
Sbjct: 243 SRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV 302
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
S + E GV L I+ + D + C+A N GQ+ S L + +K P
Sbjct: 303 RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 362
Query: 296 FLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG---TCSL 351
F+E LQ ++D V LEC+V+GVP P + W K+ E L R+ QD C L
Sbjct: 363 FIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL-THSTDRVSMHQDNHGYICLL 421
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YT A N G+ + +A L
Sbjct: 422 IQGATKEDAGWYTVSAKNEAGIVSCTARL 450
Score = 65.7 bits (153), Expect = 2e-09
Identities = 58/211 (27%), Positives = 92/211 (43%), Gaps = 31/211 (14%)
Query: 91 VPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---- 145
+ + + +P F++ + +EG L +CKV G PTP LSW DG+ ++P +++
Sbjct: 255 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 314
Query: 146 TGTNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
G +SL G Y CIA N GQ S S EL V E K P
Sbjct: 315 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV-----AAKEAHK--------PP 361
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS-RCHLGKEERGVFFLD 254
F+ L++ P R +V P P + W ++++ + S+ R + ++ G L
Sbjct: 362 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 421
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
IQ D + A N+ G + SC +L
Sbjct: 422 IQGATKEDAGWYTVSAKNEAG--IVSCTARL 450
Score = 50.8 bits (116), Expect = 8e-05
Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Query: 287 IPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ 345
I + +P FL+ + EG + ++CKV G+P P L W DG+ ++P H+++ +
Sbjct: 255 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 314
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASLL 372
+G SL G YTC A+N G + S L+
Sbjct: 315 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 351
>AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein.
Length = 1106
Score = 93.5 bits (222), Expect = 1e-17
Identities = 94/329 (28%), Positives = 141/329 (42%), Gaps = 51/329 (15%)
Query: 93 KNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP-GDVY----QLT 146
+N P F L+ EG+ V+F C+V G P P + WFKDG+++ P D Y L
Sbjct: 772 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLD 831
Query: 147 GTNSL----------GSYCCIAKNCMGQASSSAELTVEDI-------------------- 176
GT SL G+Y +A N G+ S + L V+ +
Sbjct: 832 GTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPR 891
Query: 177 -QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+++ + +E + + P F+ + + + R KV+ P P L W D +PV
Sbjct: 892 SRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV 951
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
S + E GV L I+ + D + C+A N GQ+ S L + +K P
Sbjct: 952 RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 1011
Query: 296 FLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG---TCSL 351
F+E LQ ++D V LEC+V+GVP P + W K+ E L R+ QD C L
Sbjct: 1012 FIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL-THSTDRVSMHQDNHGYICLL 1070
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YT A N G+ + +A L
Sbjct: 1071 IQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
Score = 66.9 bits (156), Expect = 1e-09
Identities = 59/216 (27%), Positives = 93/216 (43%), Gaps = 29/216 (13%)
Query: 91 VPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---- 145
+ + + +P F++ + +EG L +CKV G PTP LSW DG+ ++P +++
Sbjct: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 963
Query: 146 TGTNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
G +SL G Y CIA N GQ S S EL V E K P
Sbjct: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV-----AAKEAHK--------PP 1010
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS-RCHLGKEERGVFFLD 254
F+ L++ P R +V P P + W ++++ + S+ R + ++ G L
Sbjct: 1011 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH 290
IQ D + A N+ G + L + I RH
Sbjct: 1071 IQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
Score = 52.4 bits (120), Expect = 2e-05
Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 15/109 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL----------KPGDVYQL- 145
PRF++ L++ EG V EC+V G PTP + WF +G+EL + GD++ L
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 146 ---TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSK 191
+ G Y C+A N G ++SAE+ +E + ++ E L S+
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSR 379
Score = 51.6 bits (118), Expect = 4e-05
Identities = 31/89 (34%), Positives = 49/89 (55%), Gaps = 11/89 (12%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEEL----------KPGDIHRII 342
PRF++ L++ EG+ V LEC+V G P P ++W+ +G+EL + GD+H +I
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 343 SGQDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A+N G +SA +
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEV 359
Score = 50.8 bits (116), Expect = 8e-05
Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Query: 287 IPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ 345
I + +P FL+ + EG + ++CKV G+P P L W DG+ ++P H+++ +
Sbjct: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 963
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASLL 372
+G SL G YTC A+N G + S L+
Sbjct: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
Score = 39.9 bits (89), Expect = 0.14
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 18/100 (18%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ---- 345
Y P F + LQ EG V LEC+V G P ++W++ G E++ RI+ +
Sbjct: 438 YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
Query: 346 ---DGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ C+L G +TC A N G A S+A L+
Sbjct: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV 537
Score = 35.9 bits (79), Expect = 2.3
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 22/101 (21%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQEL---------------- 137
Y P F + LQ EG +V EC+V G P + WF+ G E+
Sbjct: 438 YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
Query: 138 -KPGDVYQL----TGTNSLGSYCCIAKNCMGQASSSAELTV 173
+P ++ L T G + C A+N G A+S+A+L V
Sbjct: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
>AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein.
Length = 772
Score = 93.5 bits (222), Expect = 1e-17
Identities = 94/329 (28%), Positives = 141/329 (42%), Gaps = 51/329 (15%)
Query: 93 KNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP-GDVY----QLT 146
+N P F L+ EG+ V+F C+V G P P + WFKDG+++ P D Y L
Sbjct: 385 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLD 444
Query: 147 GTNSL----------GSYCCIAKNCMGQASSSAELTVEDI-------------------- 176
GT SL G+Y +A N G+ S + L V+ +
Sbjct: 445 GTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPR 504
Query: 177 -QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+++ + +E + + P F+ + + + R KV+ P P L W D +PV
Sbjct: 505 SRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV 564
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
S + E GV L I+ + D + C+A N GQ+ S L + +K P
Sbjct: 565 RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 624
Query: 296 FLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG---TCSL 351
F+E LQ ++D V LEC+V+GVP P + W K+ E L R+ QD C L
Sbjct: 625 FIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL-THSTDRVSMHQDNHGYICLL 683
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G YT A N G+ + +A L
Sbjct: 684 IQGATKEDAGWYTVSAKNEAGIVSCTARL 712
Score = 65.7 bits (153), Expect = 2e-09
Identities = 58/211 (27%), Positives = 92/211 (43%), Gaps = 31/211 (14%)
Query: 91 VPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---- 145
+ + + +P F++ + +EG L +CKV G PTP LSW DG+ ++P +++
Sbjct: 517 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 576
Query: 146 TGTNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
G +SL G Y CIA N GQ S S EL V E K P
Sbjct: 577 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV-----AAKEAHK--------PP 623
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS-RCHLGKEERGVFFLD 254
F+ L++ P R +V P P + W ++++ + S+ R + ++ G L
Sbjct: 624 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 683
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
IQ D + A N+ G + SC +L
Sbjct: 684 IQGATKEDAGWYTVSAKNEAG--IVSCTARL 712
Score = 50.8 bits (116), Expect = 8e-05
Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Query: 287 IPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ 345
I + +P FL+ + EG + ++CKV G+P P L W DG+ ++P H+++ +
Sbjct: 517 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 576
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASLL 372
+G SL G YTC A+N G + S L+
Sbjct: 577 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 613
>AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein.
Length = 404
Score = 92.7 bits (220), Expect = 2e-17
Identities = 93/324 (28%), Positives = 139/324 (42%), Gaps = 51/324 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP-GDVY----QLTGTNSL 151
P F L+ EG+ V+F C+V G P P + WFKDG+++ P D Y L GT SL
Sbjct: 22 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 81
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVEDI---------------------QNQL 180
G+Y +A N G+ S + L V+ + +++
Sbjct: 82 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 141
Query: 181 NEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
+ +E + + P F+ + + + R KV+ P P L W D +PV S
Sbjct: 142 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 201
Query: 241 CHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENL 300
+ E GV L I+ + D + C+A N GQ+ S L + +K P F+E L
Sbjct: 202 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 261
Query: 301 QAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG---TCSL----- 351
Q ++D V LEC+V+GVP P + W K+ E L R+ QD C L
Sbjct: 262 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESL-THSTDRVSMHQDNHGYICLLIQGAT 320
Query: 352 ----GTYTCEASNCMGVAASSASL 371
G YT A N G+ + +A L
Sbjct: 321 KEDAGWYTVSAKNEAGIVSCTARL 344
Score = 65.7 bits (153), Expect = 2e-09
Identities = 58/211 (27%), Positives = 92/211 (43%), Gaps = 31/211 (14%)
Query: 91 VPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---- 145
+ + + +P F++ + +EG L +CKV G PTP LSW DG+ ++P +++
Sbjct: 149 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 208
Query: 146 TGTNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
G +SL G Y CIA N GQ S S EL V E K P
Sbjct: 209 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV-----AAKEAHK--------PP 255
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS-RCHLGKEERGVFFLD 254
F+ L++ P R +V P P + W ++++ + S+ R + ++ G L
Sbjct: 256 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 315
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
IQ D + A N+ G + SC +L
Sbjct: 316 IQGATKEDAGWYTVSAKNEAG--IVSCTARL 344
Score = 50.8 bits (116), Expect = 8e-05
Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 11/97 (11%)
Query: 287 IPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ 345
I + +P FL+ + EG + ++CKV G+P P L W DG+ ++P H+++ +
Sbjct: 149 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 208
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASLL 372
+G SL G YTC A+N G + S L+
Sbjct: 209 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 245
Score = 34.7 bits (76), Expect = 5.3
Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 2/104 (1%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERGVFF 252
AP F LK + P FT +VA P+P + W++D + + +S + ++ G
Sbjct: 21 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 80
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQ-SVTSCFLKLIIPRHYKKPR 295
L A D + +A N G+ S T + + + + PR
Sbjct: 81 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPR 124
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 92.3 bits (219), Expect = 3e-17
Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 38/285 (13%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG--TNSLGS 153
+ ++T +S EC+V G P P ++W KDG L G + QL + G
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A N G +L+V + + +++P+ + SV K
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSVHAPPS---------IIGNHRSPENI----SVVEK--NSVS 2405
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T + + P PS+ W++D PV S+ + R L + D ++ CV N
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNA 2462
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G+ L +++P H LE+++ + ++ +V L C+V G P P + W+KDG+ L
Sbjct: 2463 AGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQPL 2520
Query: 334 KPGDIHRIISG----QDGTCSL---GTYTCEASNCMGVAASSASL 371
+ + H IISG Q + G YTC AS+ G + S SL
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 83.8 bits (198), Expect = 9e-15
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD + L +T N G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNR-G 1973
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1974 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
R + P PSL W +D PV SS + + G L + + + D + CVA N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 2088 AAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGHP 2143
Query: 333 L--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 2144 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 1450 VPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 1508 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 1562
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ + P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 1618
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LECK G P P+L W
Sbjct: 1619 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECKAAGNPSPILTWL 1676
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 1677 KDGVPVKANDNIRIEAG 1693
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT-----------NSLGSYCCIAKNCM 162
++ EC+ P+ LSW+KDGQ LK D + + G Y C+A N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G+ ++ ++ + +KL N +G ++ + I+ P + P
Sbjct: 2752 GEDELDFDVNIQVPPSF----QKLWEIG-NMLDTGRNG-EAKDVIINNPISLYCETNAAP 2805
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P+L WY+D P+ S + + R L I + D + CVA N+ G+
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+++++P K L +L ++ A+ +EC G P P W KDG+ L D H+
Sbjct: 2863 VRVLVPPIIKGANSDLPEEVTVLVNKSAL-IECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2921
Query: 342 ISG-------QDGTCSLGTYTCEASNCMGVA 365
+S +G Y C A N G A
Sbjct: 2922 LSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 78.6 bits (185), Expect = 3e-13
Identities = 83/306 (27%), Positives = 129/306 (42%), Gaps = 43/306 (14%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK- 138
S K N + VP + P+ ENL V+ +S C+V GFP P LSW K+ Q +K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPK-SENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 139 -------PGD-VYQL--TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQL 188
PG Q+ + G Y CIA N G++ LTV + + + + L
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESL 3066
Query: 189 FSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
N V SV + + A+PP P + WY++ + + ES+ + + +
Sbjct: 3067 SVVN-----VREGTSVSLECESN-------AVPP-PVITWYKNGRMITESTHVEILADGQ 3113
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG 308
L I+ E D ++ C A N G+ + L + +P + P E + +
Sbjct: 3114 ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISN 3167
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISG-------QDGTCSLGTYTCEAS 359
V L C G+P P + W K+ + ++ D RI+SG + G YTC AS
Sbjct: 3168 PVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS 3227
Query: 360 NCMGVA 365
N G A
Sbjct: 3228 NMEGKA 3233
Score = 77.8 bits (183), Expect = 6e-13
Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS EC+ P PV++W+K+G+ + ++ G I K
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 3119
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 3120 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 3292
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 74.1 bits (174), Expect = 7e-12
Identities = 76/283 (26%), Positives = 115/283 (40%), Gaps = 46/283 (16%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD---------VYQLTGTN--S 150
E + ++ + L+ EC G P P SW KDGQ L D + Q+ T
Sbjct: 2880 EEVTVLVNKSALI--ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD 2937
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKI 208
+G Y C+A+N G A L V P V G KS + +
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVH-------------------VPPSVIGPKSENLTVVV 2978
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+ T +V+ P P L W +++QP+ ++ + R L I + D E+ C
Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT---LQIIRAKVSDGGEYTC 3035
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
+A N G+S L + +P K E+L + EG +V+LEC+ VP PV+ WY
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3094
Query: 328 KDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
K+G + + + + GQ G Y C A N G
Sbjct: 3095 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 73.7 bits (173), Expect = 9e-12
Identities = 66/262 (25%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ EC+ G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 1617
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I K A P P L W
Sbjct: 1618 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 1676 LKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 1733 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAG 1812
Score = 72.9 bits (171), Expect = 2e-11
Identities = 70/278 (25%), Positives = 111/278 (39%), Gaps = 42/278 (15%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG-------TN----SLGSYCCIA 158
E+ V+ C+V G P P ++W KDGQ L+ + + + TN G Y C+A
Sbjct: 2493 EKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ G S S L V + + P+ V ++ P +
Sbjct: 2553 SSPAGHKSRSFSLNVF-------VSPTIAGVGSDGNPE------DVTVILNSPTSLVCEA 2599
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA-EWKCVAFNDFGQS 277
P ++ W++D P++ + + R + L+ Q D A + CVA N+ G+
Sbjct: 2600 YSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQE----DNAGRYSCVATNEAGEM 2655
Query: 278 VTSCFLKLIIPRHYKKPRF----LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ +K+ IP K L + + + LEC+ +P L WYKDG+ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
K D H I+ T + G YTC ASN G
Sbjct: 2716 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 3557
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 3614 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 3671
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAG 3699
Score = 69.7 bits (163), Expect = 2e-10
Identities = 70/275 (25%), Positives = 109/275 (39%), Gaps = 39/275 (14%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPG-DVYQLTGTNSL----------GSYCCIAKNCMG 163
S C+ +P ++WFKDG L+ ++ L G +L G Y C+A N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ E+ V I +N+ + L+ +PK V+ K++ + P
Sbjct: 2654 EMIKHYEVKVY-IPPIINKGD---LWGPGLSPK------EVKIKVNNTLTLECEAYAIPS 2703
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
SL WY+D QP+ H+ G L I+ + D + CVA N G+ +
Sbjct: 2704 ASLSWYKDGQPLKSDD--HVNIAANG-HTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760
Query: 284 KLIIPRHYKKPRFLENL-----QAILSD---EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ +P ++K + N+ D ++L C+ P P L WYKDG L
Sbjct: 2761 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMG 363
D I+ G + G YTC A N G
Sbjct: 2821 SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 68.9 bits (161), Expect = 3e-10
Identities = 81/287 (28%), Positives = 118/287 (41%), Gaps = 47/287 (16%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR 1804
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 1848
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 1849 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDGE 331
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 1906 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 332 ELKPGD----IHR--IISGQDGTCS-LGTYTCEASNCMGVAASSASL 371
L ++R II + S G Y C A N G SL
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSL 2006
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 3967 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 4008
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 4065
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 4066 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 4121
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 4122 SIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 68.1 bits (159), Expect = 5e-10
Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 45/290 (15%)
Query: 103 NLQAVLTEEGLVSFECKVVGFPTPVLSWFKDG----------QELKPGDVYQLTGT--NS 150
N+ AV+ V EC+ G P P L+W KDG Q L G + LT +
Sbjct: 2019 NMVAVVVNNP-VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISD 2077
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y C+A N G+ +L V N + EE+ + + ++VE
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLIS----------QAVELLCQS 2127
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
AIPP P+L W +D P+ + + E R V L I+ + D + C A
Sbjct: 2128 D-------AIPP-PTLTWLKDGHPLLKKPGLSIS-ENRSV--LKIEDAQVQDTGRYTCEA 2176
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G++ + + + +P + L L I + ++L C+ G+P P L W K G
Sbjct: 2177 TNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIWKKKG 2234
Query: 331 EEL---KPGDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
+ G + + G+ S+ Y+C ASN G A +L
Sbjct: 2235 SPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 67.7 bits (158), Expect = 6e-10
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 3224
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 3225 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3282
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 3283 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 3341
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L ++ + ++N+EC+ G P P + W K+G L G + R
Sbjct: 3342 IRGNKDEAEKLMTLV--DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 3399
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 3400 IVRAQ--VSDVAVYTCVASNRAGV 3421
Score = 66.1 bits (154), Expect = 2e-09
Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 1408
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-- 202
+ G+ S A Q N + + P + G
Sbjct: 1409 TVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 1460
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 1518
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LEC+ G+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPM 1576
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 64.1 bits (149), Expect = 8e-09
Identities = 75/295 (25%), Positives = 114/295 (38%), Gaps = 40/295 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLT 146
P Q + T EG+ V+ CK G P P + W K G+ + G +Y ++
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 1040
Query: 147 -GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G G Y C A N G A +LTV ++ L P + L E
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEE 1096
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
+ + ++PP P + W ++ Q + S H + I D
Sbjct: 1097 VTLPCEVK-----SLPP-PIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGM 1147
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ CVA N G + L + +P K R ++L+ + V++ C G P PV+
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVIT 1203
Query: 326 WYKDGEE-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
W K G L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 1204 WSKGGSTMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Score = 62.5 bits (145), Expect = 2e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 3299
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 3300 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 3354
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 3355 LVDTSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 3411
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 3412 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 3469
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 3470 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Score = 60.9 bits (141), Expect = 7e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 1248 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 1294
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 1295 KPTIKWLHNGRELT-GREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 1352
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 1353 LKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 58.0 bits (134), Expect = 5e-07
Identities = 68/271 (25%), Positives = 104/271 (38%), Gaps = 28/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
+S C+ P P L+W+KDG L D V L G G I + + A +
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPG----GRVLQIPRAKVEDAGRYTCVA 2850
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS-----VEAKIDEPFRFTIKVAIPPEPSLL 227
V + E+ LQ + P + G S V +++ + P P
Sbjct: 2851 VNEAG-----EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W +D QP+ E R L I + D + CVA N G + L + +
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Query: 288 PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG--- 344
P P+ ENL ++++ ++L C+V G P P L W K+ + +K I+ G
Sbjct: 2963 PPSVIGPKS-ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT 3019
Query: 345 ----QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A N G + SL
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 3609
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 3610 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 3663
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 3664 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 3720
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 3721 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 3774
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 3775 VTDTGRYLCMATNAAG 3790
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/270 (22%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C G+P P ++W + + Y++T +L KN A A +
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL-----FIKNA---APKDAGIYG 680
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +++ +APK + + + + K + P P + W++ D
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ S+ + + + L IQ + LD ++ CVA N+ G++ L + P
Sbjct: 741 ELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP----- 792
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYK-DGEEL--KPGDIHRIISGQDGTC 349
P F++ + + G+ V L C V G P+P +KW + D + +P + I + G
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
+ GTY CEA N G S ++
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTV 882
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 4068
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 4069 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 4110
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 4167 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 4221
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 4222 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 3694
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 3695 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 3750
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 3751 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3808
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 3809 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 3844
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 1157 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 1255
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 1256 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 1307
Score = 48.8 bits (111), Expect = 3e-04
Identities = 79/304 (25%), Positives = 116/304 (38%), Gaps = 58/304 (19%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ M +L G ++ ECK G P P + WFK EL+P + ++
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 148 TNSL--GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
T L G Y C+A N G+A+ L V P F+ V
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDV------------------GSPPVFIQEPADVS 803
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYR-DDQPVDES--SRCHLGKEERGVFFLDIQALEFLD 262
+I V PEP++ W R D+ P+ S + + G F I L D
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF--ILNLWASD 861
Query: 263 QAEWKCVAFNDFG--QSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVI-G 318
+ + C A N FG QS T+ + L+ P P A + + + L C ++ G
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV-----ANVIEGQQLTLPCTLLAG 916
Query: 319 VPQPVLKWYKDGEEL---------KPGDIH-RIISGQDGTCSLGTYTCEASNCMGVAASS 368
P P +W K+ L G +H + QDG G YTC ASN G +
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG----GEYTCVASNVAGTNNKT 972
Query: 369 ASLL 372
S++
Sbjct: 973 TSVV 976
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 4149 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 4195
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 4196 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 4245
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 4246 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 4335
Score = 46.4 bits (105), Expect = 0.002
Identities = 68/283 (24%), Positives = 104/283 (36%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 4239
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 4240 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 4281
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 4282 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 4336
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
F+ + P +K + N L +N C+V G P P ++W + G +++
Sbjct: 4337 VKAIGFVYVKEPPVFKGD-YPSNWIEPLGGNAILN--CEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 4394 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 4377 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 4433 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488
Query: 342 IS 343
+S
Sbjct: 4489 LS 4490
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 3793 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 3891
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 3892 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 3947
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 4365 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 4423
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 4424 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 4475 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 4516
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 4444 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 4503
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 4504 TSEFECVARNLMG 4516
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 92.3 bits (219), Expect = 3e-17
Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 38/285 (13%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG--TNSLGS 153
+ ++T +S EC+V G P P ++W KDG L G + QL + G
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A N G +L+V + + +++P+ + SV K
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSVHAPPS---------IIGNHRSPENI----SVVEK--NSVS 2405
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T + + P PS+ W++D PV S+ + R L + D ++ CV N
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNA 2462
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G+ L +++P H LE+++ + ++ +V L C+V G P P + W+KDG+ L
Sbjct: 2463 AGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQPL 2520
Query: 334 KPGDIHRIISG----QDGTCSL---GTYTCEASNCMGVAASSASL 371
+ + H IISG Q + G YTC AS+ G + S SL
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 83.8 bits (198), Expect = 9e-15
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD + L +T N G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNR-G 1973
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1974 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
R + P PSL W +D PV SS + + G L + + + D + CVA N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 2088 AAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGHP 2143
Query: 333 L--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 2144 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 1450 VPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 1508 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 1562
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ + P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 1618
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LECK G P P+L W
Sbjct: 1619 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECKAAGNPSPILTWL 1676
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 1677 KDGVPVKANDNIRIEAG 1693
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT-----------NSLGSYCCIAKNCM 162
++ EC+ P+ LSW+KDGQ LK D + + G Y C+A N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G+ ++ ++ + +KL N +G ++ + I+ P + P
Sbjct: 2752 GEDELDFDVNIQVPPSF----QKLWEIG-NMLDTGRNG-EAKDVIINNPISLYCETNAAP 2805
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P+L WY+D P+ S + + R L I + D + CVA N+ G+
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+++++P K L +L ++ A+ +EC G P P W KDG+ L D H+
Sbjct: 2863 VRVLVPPIIKGANSDLPEEVTVLVNKSAL-IECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2921
Query: 342 ISG-------QDGTCSLGTYTCEASNCMGVA 365
+S +G Y C A N G A
Sbjct: 2922 LSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 78.6 bits (185), Expect = 3e-13
Identities = 83/306 (27%), Positives = 129/306 (42%), Gaps = 43/306 (14%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK- 138
S K N + VP + P+ ENL V+ +S C+V GFP P LSW K+ Q +K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPK-SENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 139 -------PGD-VYQL--TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQL 188
PG Q+ + G Y CIA N G++ LTV + + + + L
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESL 3066
Query: 189 FSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
N V SV + + A+PP P + WY++ + + ES+ + + +
Sbjct: 3067 SVVN-----VREGTSVSLECESN-------AVPP-PVITWYKNGRMITESTHVEILADGQ 3113
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG 308
L I+ E D ++ C A N G+ + L + +P + P E + +
Sbjct: 3114 ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISN 3167
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISG-------QDGTCSLGTYTCEAS 359
V L C G+P P + W K+ + ++ D RI+SG + G YTC AS
Sbjct: 3168 PVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS 3227
Query: 360 NCMGVA 365
N G A
Sbjct: 3228 NMEGKA 3233
Score = 77.8 bits (183), Expect = 6e-13
Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS EC+ P PV++W+K+G+ + ++ G I K
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 3119
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 3120 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 3292
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 74.1 bits (174), Expect = 7e-12
Identities = 76/283 (26%), Positives = 115/283 (40%), Gaps = 46/283 (16%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD---------VYQLTGTN--S 150
E + ++ + L+ EC G P P SW KDGQ L D + Q+ T
Sbjct: 2880 EEVTVLVNKSALI--ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD 2937
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKI 208
+G Y C+A+N G A L V P V G KS + +
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVH-------------------VPPSVIGPKSENLTVVV 2978
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+ T +V+ P P L W +++QP+ ++ + R L I + D E+ C
Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT---LQIIRAKVSDGGEYTC 3035
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
+A N G+S L + +P K E+L + EG +V+LEC+ VP PV+ WY
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3094
Query: 328 KDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
K+G + + + + GQ G Y C A N G
Sbjct: 3095 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 73.7 bits (173), Expect = 9e-12
Identities = 66/262 (25%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ EC+ G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 1617
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I K A P P L W
Sbjct: 1618 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 1676 LKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 1733 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAG 1812
Score = 72.9 bits (171), Expect = 2e-11
Identities = 70/278 (25%), Positives = 111/278 (39%), Gaps = 42/278 (15%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG-------TN----SLGSYCCIA 158
E+ V+ C+V G P P ++W KDGQ L+ + + + TN G Y C+A
Sbjct: 2493 EKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ G S S L V + + P+ V ++ P +
Sbjct: 2553 SSPAGHKSRSFSLNVF-------VSPTIAGVGSDGNPE------DVTVILNSPTSLVCEA 2599
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA-EWKCVAFNDFGQS 277
P ++ W++D P++ + + R + L+ Q D A + CVA N+ G+
Sbjct: 2600 YSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQE----DNAGRYSCVATNEAGEM 2655
Query: 278 VTSCFLKLIIPRHYKKPRF----LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ +K+ IP K L + + + LEC+ +P L WYKDG+ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
K D H I+ T + G YTC ASN G
Sbjct: 2716 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 3557
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 3614 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 3671
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAG 3699
Score = 69.7 bits (163), Expect = 2e-10
Identities = 70/275 (25%), Positives = 109/275 (39%), Gaps = 39/275 (14%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPG-DVYQLTGTNSL----------GSYCCIAKNCMG 163
S C+ +P ++WFKDG L+ ++ L G +L G Y C+A N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ E+ V I +N+ + L+ +PK V+ K++ + P
Sbjct: 2654 EMIKHYEVKVY-IPPIINKGD---LWGPGLSPK------EVKIKVNNTLTLECEAYAIPS 2703
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
SL WY+D QP+ H+ G L I+ + D + CVA N G+ +
Sbjct: 2704 ASLSWYKDGQPLKSDD--HVNIAANG-HTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760
Query: 284 KLIIPRHYKKPRFLENL-----QAILSD---EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ +P ++K + N+ D ++L C+ P P L WYKDG L
Sbjct: 2761 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMG 363
D I+ G + G YTC A N G
Sbjct: 2821 SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 68.9 bits (161), Expect = 3e-10
Identities = 81/287 (28%), Positives = 118/287 (41%), Gaps = 47/287 (16%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR 1804
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 1848
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 1849 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDGE 331
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 1906 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 332 ELKPGD----IHR--IISGQDGTCS-LGTYTCEASNCMGVAASSASL 371
L ++R II + S G Y C A N G SL
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSL 2006
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 3967 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 4008
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 4065
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 4066 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 4121
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 4122 SIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 68.1 bits (159), Expect = 5e-10
Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 45/290 (15%)
Query: 103 NLQAVLTEEGLVSFECKVVGFPTPVLSWFKDG----------QELKPGDVYQLTGT--NS 150
N+ AV+ V EC+ G P P L+W KDG Q L G + LT +
Sbjct: 2019 NMVAVVVNNP-VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISD 2077
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y C+A N G+ +L V N + EE+ + + ++VE
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLIS----------QAVELLCQS 2127
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
AIPP P+L W +D P+ + + E R V L I+ + D + C A
Sbjct: 2128 D-------AIPP-PTLTWLKDGHPLLKKPGLSIS-ENRSV--LKIEDAQVQDTGRYTCEA 2176
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G++ + + + +P + L L I + ++L C+ G+P P L W K G
Sbjct: 2177 TNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIWKKKG 2234
Query: 331 EEL---KPGDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
+ G + + G+ S+ Y+C ASN G A +L
Sbjct: 2235 SPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 67.7 bits (158), Expect = 6e-10
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 3224
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 3225 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3282
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 3283 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 3341
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L ++ + ++N+EC+ G P P + W K+G L G + R
Sbjct: 3342 IRGNKDEAEKLMTLV--DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 3399
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 3400 IVRAQ--VSDVAVYTCVASNRAGV 3421
Score = 66.1 bits (154), Expect = 2e-09
Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 1408
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-- 202
+ G+ S A Q N + + P + G
Sbjct: 1409 TVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 1460
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 1518
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LEC+ G+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPM 1576
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 64.1 bits (149), Expect = 8e-09
Identities = 75/295 (25%), Positives = 114/295 (38%), Gaps = 40/295 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLT 146
P Q + T EG+ V+ CK G P P + W K G+ + G +Y ++
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 1040
Query: 147 -GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G G Y C A N G A +LTV ++ L P + L E
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEE 1096
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
+ + ++PP P + W ++ Q + S H + I D
Sbjct: 1097 VTLPCEVK-----SLPP-PIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGM 1147
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ CVA N G + L + +P K R ++L+ + V++ C G P PV+
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVIT 1203
Query: 326 WYKDGEE-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
W K G L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 1204 WSKGGSTMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Score = 62.5 bits (145), Expect = 2e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 3299
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 3300 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 3354
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 3355 LVDTSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 3411
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 3412 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 3469
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 3470 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Score = 60.9 bits (141), Expect = 7e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 1248 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 1294
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 1295 KPTIKWLHNGRELT-GREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 1352
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 1353 LKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 58.0 bits (134), Expect = 5e-07
Identities = 68/271 (25%), Positives = 104/271 (38%), Gaps = 28/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
+S C+ P P L+W+KDG L D V L G G I + + A +
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPG----GRVLQIPRAKVEDAGRYTCVA 2850
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS-----VEAKIDEPFRFTIKVAIPPEPSLL 227
V + E+ LQ + P + G S V +++ + P P
Sbjct: 2851 VNEAG-----EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W +D QP+ E R L I + D + CVA N G + L + +
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Query: 288 PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG--- 344
P P+ ENL ++++ ++L C+V G P P L W K+ + +K I+ G
Sbjct: 2963 PPSVIGPKS-ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT 3019
Query: 345 ----QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A N G + SL
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 3609
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 3610 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 3663
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 3664 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 3720
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 3721 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 3774
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 3775 VTDTGRYLCMATNAAG 3790
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/270 (22%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C G+P P ++W + + Y++T +L KN A A +
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL-----FIKNA---APKDAGIYG 680
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +++ +APK + + + + K + P P + W++ D
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ S+ + + + L IQ + LD ++ CVA N+ G++ L + P
Sbjct: 741 ELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP----- 792
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYK-DGEEL--KPGDIHRIISGQDGTC 349
P F++ + + G+ V L C V G P+P +KW + D + +P + I + G
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
+ GTY CEA N G S ++
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTV 882
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 4068
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 4069 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 4110
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 4167 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 4221
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 4222 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 3694
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 3695 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 3750
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 3751 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3808
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 3809 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 3844
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 1157 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 1255
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 1256 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 1307
Score = 48.8 bits (111), Expect = 3e-04
Identities = 79/304 (25%), Positives = 116/304 (38%), Gaps = 58/304 (19%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ M +L G ++ ECK G P P + WFK EL+P + ++
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 148 TNSL--GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
T L G Y C+A N G+A+ L V P F+ V
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDV------------------GSPPVFIQEPADVS 803
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYR-DDQPVDES--SRCHLGKEERGVFFLDIQALEFLD 262
+I V PEP++ W R D+ P+ S + + G F I L D
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF--ILNLWASD 861
Query: 263 QAEWKCVAFNDFG--QSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVI-G 318
+ + C A N FG QS T+ + L+ P P A + + + L C ++ G
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV-----ANVIEGQQLTLPCTLLAG 916
Query: 319 VPQPVLKWYKDGEEL---------KPGDIH-RIISGQDGTCSLGTYTCEASNCMGVAASS 368
P P +W K+ L G +H + QDG G YTC ASN G +
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG----GEYTCVASNVAGTNNKT 972
Query: 369 ASLL 372
S++
Sbjct: 973 TSVV 976
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 4149 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 4195
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 4196 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 4245
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 4246 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 4335
Score = 46.4 bits (105), Expect = 0.002
Identities = 68/283 (24%), Positives = 104/283 (36%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 4239
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 4240 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 4281
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 4282 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 4336
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
F+ + P +K + N L +N C+V G P P ++W + G +++
Sbjct: 4337 VKAIGFVYVKEPPVFKGD-YPSNWIEPLGGNAILN--CEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 4394 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 4377 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 4433 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488
Query: 342 IS 343
+S
Sbjct: 4489 LS 4490
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 3793 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 3891
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 3892 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 3947
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 4365 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 4423
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 4424 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 4475 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 4516
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 4444 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 4503
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 4504 TSEFECVARNLMG 4516
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 92.3 bits (219), Expect = 3e-17
Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 38/285 (13%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG--TNSLGS 153
+ ++T +S EC+V G P P ++W KDG L G + QL + G
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A N G +L+V + + +++P+ + SV K
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSVHAPPS---------IIGNHRSPENI----SVVEK--NSVS 2405
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T + + P PS+ W++D PV S+ + R L + D ++ CV N
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNA 2462
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G+ L +++P H LE+++ + ++ +V L C+V G P P + W+KDG+ L
Sbjct: 2463 AGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQPL 2520
Query: 334 KPGDIHRIISG----QDGTCSL---GTYTCEASNCMGVAASSASL 371
+ + H IISG Q + G YTC AS+ G + S SL
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 83.8 bits (198), Expect = 9e-15
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD + L +T N G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNR-G 1973
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1974 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
R + P PSL W +D PV SS + + G L + + + D + CVA N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 2088 AAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGHP 2143
Query: 333 L--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 2144 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 1450 VPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 1508 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 1562
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ + P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 1618
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LECK G P P+L W
Sbjct: 1619 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECKAAGNPSPILTWL 1676
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 1677 KDGVPVKANDNIRIEAG 1693
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT-----------NSLGSYCCIAKNCM 162
++ EC+ P+ LSW+KDGQ LK D + + G Y C+A N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G+ ++ ++ + +KL N +G ++ + I+ P + P
Sbjct: 2752 GEDELDFDVNIQVPPSF----QKLWEIG-NMLDTGRNG-EAKDVIINNPISLYCETNAAP 2805
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P+L WY+D P+ S + + R L I + D + CVA N+ G+
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+++++P K L +L ++ A+ +EC G P P W KDG+ L D H+
Sbjct: 2863 VRVLVPPIIKGANSDLPEEVTVLVNKSAL-IECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2921
Query: 342 ISG-------QDGTCSLGTYTCEASNCMGVA 365
+S +G Y C A N G A
Sbjct: 2922 LSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 78.6 bits (185), Expect = 3e-13
Identities = 83/306 (27%), Positives = 129/306 (42%), Gaps = 43/306 (14%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK- 138
S K N + VP + P+ ENL V+ +S C+V GFP P LSW K+ Q +K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPK-SENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 139 -------PGD-VYQL--TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQL 188
PG Q+ + G Y CIA N G++ LTV + + + + L
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESL 3066
Query: 189 FSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
N V SV + + A+PP P + WY++ + + ES+ + + +
Sbjct: 3067 SVVN-----VREGTSVSLECESN-------AVPP-PVITWYKNGRMITESTHVEILADGQ 3113
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG 308
L I+ E D ++ C A N G+ + L + +P + P E + +
Sbjct: 3114 ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISN 3167
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISG-------QDGTCSLGTYTCEAS 359
V L C G+P P + W K+ + ++ D RI+SG + G YTC AS
Sbjct: 3168 PVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS 3227
Query: 360 NCMGVA 365
N G A
Sbjct: 3228 NMEGKA 3233
Score = 77.8 bits (183), Expect = 6e-13
Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS EC+ P PV++W+K+G+ + ++ G I K
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 3119
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 3120 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 3292
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 74.1 bits (174), Expect = 7e-12
Identities = 76/283 (26%), Positives = 115/283 (40%), Gaps = 46/283 (16%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD---------VYQLTGTN--S 150
E + ++ + L+ EC G P P SW KDGQ L D + Q+ T
Sbjct: 2880 EEVTVLVNKSALI--ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD 2937
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKI 208
+G Y C+A+N G A L V P V G KS + +
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVH-------------------VPPSVIGPKSENLTVVV 2978
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+ T +V+ P P L W +++QP+ ++ + R L I + D E+ C
Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT---LQIIRAKVSDGGEYTC 3035
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
+A N G+S L + +P K E+L + EG +V+LEC+ VP PV+ WY
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3094
Query: 328 KDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
K+G + + + + GQ G Y C A N G
Sbjct: 3095 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 73.7 bits (173), Expect = 9e-12
Identities = 66/262 (25%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ EC+ G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 1617
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I K A P P L W
Sbjct: 1618 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 1676 LKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 1733 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAG 1812
Score = 72.9 bits (171), Expect = 2e-11
Identities = 70/278 (25%), Positives = 111/278 (39%), Gaps = 42/278 (15%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG-------TN----SLGSYCCIA 158
E+ V+ C+V G P P ++W KDGQ L+ + + + TN G Y C+A
Sbjct: 2493 EKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ G S S L V + + P+ V ++ P +
Sbjct: 2553 SSPAGHKSRSFSLNVF-------VSPTIAGVGSDGNPE------DVTVILNSPTSLVCEA 2599
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA-EWKCVAFNDFGQS 277
P ++ W++D P++ + + R + L+ Q D A + CVA N+ G+
Sbjct: 2600 YSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQE----DNAGRYSCVATNEAGEM 2655
Query: 278 VTSCFLKLIIPRHYKKPRF----LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ +K+ IP K L + + + LEC+ +P L WYKDG+ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
K D H I+ T + G YTC ASN G
Sbjct: 2716 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 3557
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 3614 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 3671
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAG 3699
Score = 69.7 bits (163), Expect = 2e-10
Identities = 70/275 (25%), Positives = 109/275 (39%), Gaps = 39/275 (14%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPG-DVYQLTGTNSL----------GSYCCIAKNCMG 163
S C+ +P ++WFKDG L+ ++ L G +L G Y C+A N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ E+ V I +N+ + L+ +PK V+ K++ + P
Sbjct: 2654 EMIKHYEVKVY-IPPIINKGD---LWGPGLSPK------EVKIKVNNTLTLECEAYAIPS 2703
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
SL WY+D QP+ H+ G L I+ + D + CVA N G+ +
Sbjct: 2704 ASLSWYKDGQPLKSDD--HVNIAANG-HTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760
Query: 284 KLIIPRHYKKPRFLENL-----QAILSD---EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ +P ++K + N+ D ++L C+ P P L WYKDG L
Sbjct: 2761 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMG 363
D I+ G + G YTC A N G
Sbjct: 2821 SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 68.9 bits (161), Expect = 3e-10
Identities = 81/287 (28%), Positives = 118/287 (41%), Gaps = 47/287 (16%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR 1804
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 1848
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 1849 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDGE 331
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 1906 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 332 ELKPGD----IHR--IISGQDGTCS-LGTYTCEASNCMGVAASSASL 371
L ++R II + S G Y C A N G SL
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSL 2006
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 3967 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 4008
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 4065
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 4066 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 4121
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 4122 SIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 68.1 bits (159), Expect = 5e-10
Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 45/290 (15%)
Query: 103 NLQAVLTEEGLVSFECKVVGFPTPVLSWFKDG----------QELKPGDVYQLTGT--NS 150
N+ AV+ V EC+ G P P L+W KDG Q L G + LT +
Sbjct: 2019 NMVAVVVNNP-VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISD 2077
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y C+A N G+ +L V N + EE+ + + ++VE
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLIS----------QAVELLCQS 2127
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
AIPP P+L W +D P+ + + E R V L I+ + D + C A
Sbjct: 2128 D-------AIPP-PTLTWLKDGHPLLKKPGLSIS-ENRSV--LKIEDAQVQDTGRYTCEA 2176
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G++ + + + +P + L L I + ++L C+ G+P P L W K G
Sbjct: 2177 TNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIWKKKG 2234
Query: 331 EEL---KPGDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
+ G + + G+ S+ Y+C ASN G A +L
Sbjct: 2235 SPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 67.7 bits (158), Expect = 6e-10
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 3224
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 3225 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3282
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 3283 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 3341
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L ++ + ++N+EC+ G P P + W K+G L G + R
Sbjct: 3342 IRGNKDEAEKLMTLV--DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 3399
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 3400 IVRAQ--VSDVAVYTCVASNRAGV 3421
Score = 66.1 bits (154), Expect = 2e-09
Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 1408
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-- 202
+ G+ S A Q N + + P + G
Sbjct: 1409 TVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 1460
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 1518
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LEC+ G+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPM 1576
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 64.1 bits (149), Expect = 8e-09
Identities = 75/295 (25%), Positives = 114/295 (38%), Gaps = 40/295 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLT 146
P Q + T EG+ V+ CK G P P + W K G+ + G +Y ++
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 1040
Query: 147 -GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G G Y C A N G A +LTV ++ L P + L E
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEE 1096
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
+ + ++PP P + W ++ Q + S H + I D
Sbjct: 1097 VTLPCEVK-----SLPP-PIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGM 1147
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ CVA N G + L + +P K R ++L+ + V++ C G P PV+
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVIT 1203
Query: 326 WYKDGEE-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
W K G L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 1204 WSKGGSTMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Score = 62.5 bits (145), Expect = 2e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 3299
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 3300 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 3354
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 3355 LVDTSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 3411
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 3412 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 3469
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 3470 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Score = 60.9 bits (141), Expect = 7e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 1248 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 1294
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 1295 KPTIKWLHNGRELT-GREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 1352
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 1353 LKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 58.0 bits (134), Expect = 5e-07
Identities = 68/271 (25%), Positives = 104/271 (38%), Gaps = 28/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
+S C+ P P L+W+KDG L D V L G G I + + A +
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPG----GRVLQIPRAKVEDAGRYTCVA 2850
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS-----VEAKIDEPFRFTIKVAIPPEPSLL 227
V + E+ LQ + P + G S V +++ + P P
Sbjct: 2851 VNEAG-----EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W +D QP+ E R L I + D + CVA N G + L + +
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Query: 288 PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG--- 344
P P+ ENL ++++ ++L C+V G P P L W K+ + +K I+ G
Sbjct: 2963 PPSVIGPKS-ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT 3019
Query: 345 ----QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A N G + SL
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 3609
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 3610 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 3663
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 3664 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 3720
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 3721 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 3774
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 3775 VTDTGRYLCMATNAAG 3790
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/270 (22%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C G+P P ++W + + Y++T +L KN A A +
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL-----FIKNA---APKDAGIYG 680
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +++ +APK + + + + K + P P + W++ D
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ S+ + + + L IQ + LD ++ CVA N+ G++ L + P
Sbjct: 741 ELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP----- 792
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYK-DGEEL--KPGDIHRIISGQDGTC 349
P F++ + + G+ V L C V G P+P +KW + D + +P + I + G
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
+ GTY CEA N G S ++
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTV 882
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 4068
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 4069 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 4110
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 4167 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 4221
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 4222 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 3694
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 3695 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 3750
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 3751 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3808
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 3809 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 3844
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 1157 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 1255
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 1256 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 1307
Score = 48.8 bits (111), Expect = 3e-04
Identities = 79/304 (25%), Positives = 116/304 (38%), Gaps = 58/304 (19%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ M +L G ++ ECK G P P + WFK EL+P + ++
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 148 TNSL--GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
T L G Y C+A N G+A+ L V P F+ V
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDV------------------GSPPVFIQEPADVS 803
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYR-DDQPVDES--SRCHLGKEERGVFFLDIQALEFLD 262
+I V PEP++ W R D+ P+ S + + G F I L D
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF--ILNLWASD 861
Query: 263 QAEWKCVAFNDFG--QSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVI-G 318
+ + C A N FG QS T+ + L+ P P A + + + L C ++ G
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV-----ANVIEGQQLTLPCTLLAG 916
Query: 319 VPQPVLKWYKDGEEL---------KPGDIH-RIISGQDGTCSLGTYTCEASNCMGVAASS 368
P P +W K+ L G +H + QDG G YTC ASN G +
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG----GEYTCVASNVAGTNNKT 972
Query: 369 ASLL 372
S++
Sbjct: 973 TSVV 976
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 4149 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 4195
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 4196 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 4245
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 4246 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 4335
Score = 46.4 bits (105), Expect = 0.002
Identities = 68/283 (24%), Positives = 104/283 (36%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 4239
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 4240 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 4281
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 4282 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 4336
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
F+ + P +K + N L +N C+V G P P ++W + G +++
Sbjct: 4337 VKAIGFVYVKEPPVFKGD-YPSNWIEPLGGNAILN--CEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 4394 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 4377 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 4433 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488
Query: 342 IS 343
+S
Sbjct: 4489 LS 4490
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 3793 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 3891
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 3892 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 3947
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 4365 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 4423
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 4424 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 4475 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 4516
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 4444 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 4503
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 4504 TSEFECVARNLMG 4516
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 92.3 bits (219), Expect = 3e-17
Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 38/285 (13%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG--TNSLGS 153
+ ++T +S EC+V G P P ++W KDG L G + QL + G
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A N G +L+V + + +++P+ + SV K
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSVHAPPS---------IIGNHRSPENI----SVVEK--NSVS 2405
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T + + P PS+ W++D PV S+ + R L + D ++ CV N
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNA 2462
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G+ L +++P H LE+++ + ++ +V L C+V G P P + W+KDG+ L
Sbjct: 2463 AGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQPL 2520
Query: 334 KPGDIHRIISG----QDGTCSL---GTYTCEASNCMGVAASSASL 371
+ + H IISG Q + G YTC AS+ G + S SL
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 83.8 bits (198), Expect = 9e-15
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD + L +T N G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNR-G 1973
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1974 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
R + P PSL W +D PV SS + + G L + + + D + CVA N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 2088 AAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGHP 2143
Query: 333 L--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 2144 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 1450 VPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 1508 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 1562
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ + P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 1618
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LECK G P P+L W
Sbjct: 1619 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECKAAGNPSPILTWL 1676
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 1677 KDGVPVKANDNIRIEAG 1693
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT-----------NSLGSYCCIAKNCM 162
++ EC+ P+ LSW+KDGQ LK D + + G Y C+A N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G+ ++ ++ + +KL N +G ++ + I+ P + P
Sbjct: 2752 GEDELDFDVNIQVPPSF----QKLWEIG-NMLDTGRNG-EAKDVIINNPISLYCETNAAP 2805
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P+L WY+D P+ S + + R L I + D + CVA N+ G+
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+++++P K L +L ++ A+ +EC G P P W KDG+ L D H+
Sbjct: 2863 VRVLVPPIIKGANSDLPEEVTVLVNKSAL-IECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2921
Query: 342 ISG-------QDGTCSLGTYTCEASNCMGVA 365
+S +G Y C A N G A
Sbjct: 2922 LSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 78.6 bits (185), Expect = 3e-13
Identities = 83/306 (27%), Positives = 129/306 (42%), Gaps = 43/306 (14%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK- 138
S K N + VP + P+ ENL V+ +S C+V GFP P LSW K+ Q +K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPK-SENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 139 -------PGD-VYQL--TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQL 188
PG Q+ + G Y CIA N G++ LTV + + + + L
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESL 3066
Query: 189 FSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
N V SV + + A+PP P + WY++ + + ES+ + + +
Sbjct: 3067 SVVN-----VREGTSVSLECESN-------AVPP-PVITWYKNGRMITESTHVEILADGQ 3113
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG 308
L I+ E D ++ C A N G+ + L + +P + P E + +
Sbjct: 3114 ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISN 3167
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISG-------QDGTCSLGTYTCEAS 359
V L C G+P P + W K+ + ++ D RI+SG + G YTC AS
Sbjct: 3168 PVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS 3227
Query: 360 NCMGVA 365
N G A
Sbjct: 3228 NMEGKA 3233
Score = 77.8 bits (183), Expect = 6e-13
Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS EC+ P PV++W+K+G+ + ++ G I K
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 3119
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 3120 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 3292
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 74.1 bits (174), Expect = 7e-12
Identities = 76/283 (26%), Positives = 115/283 (40%), Gaps = 46/283 (16%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD---------VYQLTGTN--S 150
E + ++ + L+ EC G P P SW KDGQ L D + Q+ T
Sbjct: 2880 EEVTVLVNKSALI--ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD 2937
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKI 208
+G Y C+A+N G A L V P V G KS + +
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVH-------------------VPPSVIGPKSENLTVVV 2978
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+ T +V+ P P L W +++QP+ ++ + R L I + D E+ C
Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT---LQIIRAKVSDGGEYTC 3035
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
+A N G+S L + +P K E+L + EG +V+LEC+ VP PV+ WY
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3094
Query: 328 KDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
K+G + + + + GQ G Y C A N G
Sbjct: 3095 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 73.7 bits (173), Expect = 9e-12
Identities = 66/262 (25%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ EC+ G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 1617
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I K A P P L W
Sbjct: 1618 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 1676 LKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 1733 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAG 1812
Score = 72.9 bits (171), Expect = 2e-11
Identities = 70/278 (25%), Positives = 111/278 (39%), Gaps = 42/278 (15%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG-------TN----SLGSYCCIA 158
E+ V+ C+V G P P ++W KDGQ L+ + + + TN G Y C+A
Sbjct: 2493 EKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ G S S L V + + P+ V ++ P +
Sbjct: 2553 SSPAGHKSRSFSLNVF-------VSPTIAGVGSDGNPE------DVTVILNSPTSLVCEA 2599
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA-EWKCVAFNDFGQS 277
P ++ W++D P++ + + R + L+ Q D A + CVA N+ G+
Sbjct: 2600 YSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQE----DNAGRYSCVATNEAGEM 2655
Query: 278 VTSCFLKLIIPRHYKKPRF----LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ +K+ IP K L + + + LEC+ +P L WYKDG+ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
K D H I+ T + G YTC ASN G
Sbjct: 2716 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 3557
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 3614 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 3671
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAG 3699
Score = 69.7 bits (163), Expect = 2e-10
Identities = 70/275 (25%), Positives = 109/275 (39%), Gaps = 39/275 (14%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPG-DVYQLTGTNSL----------GSYCCIAKNCMG 163
S C+ +P ++WFKDG L+ ++ L G +L G Y C+A N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ E+ V I +N+ + L+ +PK V+ K++ + P
Sbjct: 2654 EMIKHYEVKVY-IPPIINKGD---LWGPGLSPK------EVKIKVNNTLTLECEAYAIPS 2703
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
SL WY+D QP+ H+ G L I+ + D + CVA N G+ +
Sbjct: 2704 ASLSWYKDGQPLKSDD--HVNIAANG-HTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760
Query: 284 KLIIPRHYKKPRFLENL-----QAILSD---EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ +P ++K + N+ D ++L C+ P P L WYKDG L
Sbjct: 2761 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMG 363
D I+ G + G YTC A N G
Sbjct: 2821 SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 68.9 bits (161), Expect = 3e-10
Identities = 81/287 (28%), Positives = 118/287 (41%), Gaps = 47/287 (16%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR 1804
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 1848
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 1849 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDGE 331
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 1906 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 332 ELKPGD----IHR--IISGQDGTCS-LGTYTCEASNCMGVAASSASL 371
L ++R II + S G Y C A N G SL
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSL 2006
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 3967 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 4008
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 4065
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 4066 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 4121
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 4122 SIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 68.1 bits (159), Expect = 5e-10
Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 45/290 (15%)
Query: 103 NLQAVLTEEGLVSFECKVVGFPTPVLSWFKDG----------QELKPGDVYQLTGT--NS 150
N+ AV+ V EC+ G P P L+W KDG Q L G + LT +
Sbjct: 2019 NMVAVVVNNP-VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISD 2077
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y C+A N G+ +L V N + EE+ + + ++VE
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLIS----------QAVELLCQS 2127
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
AIPP P+L W +D P+ + + E R V L I+ + D + C A
Sbjct: 2128 D-------AIPP-PTLTWLKDGHPLLKKPGLSIS-ENRSV--LKIEDAQVQDTGRYTCEA 2176
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G++ + + + +P + L L I + ++L C+ G+P P L W K G
Sbjct: 2177 TNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIWKKKG 2234
Query: 331 EEL---KPGDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
+ G + + G+ S+ Y+C ASN G A +L
Sbjct: 2235 SPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 67.7 bits (158), Expect = 6e-10
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 3224
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 3225 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3282
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 3283 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 3341
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L ++ + ++N+EC+ G P P + W K+G L G + R
Sbjct: 3342 IRGNKDEAEKLMTLV--DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 3399
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 3400 IVRAQ--VSDVAVYTCVASNRAGV 3421
Score = 66.1 bits (154), Expect = 2e-09
Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 1408
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-- 202
+ G+ S A Q N + + P + G
Sbjct: 1409 TVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 1460
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 1518
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LEC+ G+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPM 1576
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 64.1 bits (149), Expect = 8e-09
Identities = 75/295 (25%), Positives = 114/295 (38%), Gaps = 40/295 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLT 146
P Q + T EG+ V+ CK G P P + W K G+ + G +Y ++
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 1040
Query: 147 -GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G G Y C A N G A +LTV ++ L P + L E
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEE 1096
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
+ + ++PP P + W ++ Q + S H + I D
Sbjct: 1097 VTLPCEVK-----SLPP-PIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGM 1147
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ CVA N G + L + +P K R ++L+ + V++ C G P PV+
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVIT 1203
Query: 326 WYKDGEE-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
W K G L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 1204 WSKGGSTMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Score = 62.5 bits (145), Expect = 2e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 3299
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 3300 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 3354
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 3355 LVDTSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 3411
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 3412 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 3469
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 3470 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Score = 60.9 bits (141), Expect = 7e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 1248 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 1294
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 1295 KPTIKWLHNGRELT-GREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 1352
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 1353 LKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 58.0 bits (134), Expect = 5e-07
Identities = 68/271 (25%), Positives = 104/271 (38%), Gaps = 28/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
+S C+ P P L+W+KDG L D V L G G I + + A +
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPG----GRVLQIPRAKVEDAGRYTCVA 2850
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS-----VEAKIDEPFRFTIKVAIPPEPSLL 227
V + E+ LQ + P + G S V +++ + P P
Sbjct: 2851 VNEAG-----EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W +D QP+ E R L I + D + CVA N G + L + +
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Query: 288 PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG--- 344
P P+ ENL ++++ ++L C+V G P P L W K+ + +K I+ G
Sbjct: 2963 PPSVIGPKS-ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT 3019
Query: 345 ----QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A N G + SL
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 3609
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 3610 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 3663
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 3664 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 3720
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 3721 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 3774
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 3775 VTDTGRYLCMATNAAG 3790
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/270 (22%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C G+P P ++W + + Y++T +L KN A A +
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL-----FIKNA---APKDAGIYG 680
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +++ +APK + + + + K + P P + W++ D
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ S+ + + + L IQ + LD ++ CVA N+ G++ L + P
Sbjct: 741 ELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP----- 792
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYK-DGEEL--KPGDIHRIISGQDGTC 349
P F++ + + G+ V L C V G P+P +KW + D + +P + I + G
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
+ GTY CEA N G S ++
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTV 882
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 4068
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 4069 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 4110
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 4167 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 4221
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 4222 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 3694
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 3695 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 3750
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 3751 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3808
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 3809 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 3844
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 1157 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 1255
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 1256 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 1307
Score = 48.8 bits (111), Expect = 3e-04
Identities = 79/304 (25%), Positives = 116/304 (38%), Gaps = 58/304 (19%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ M +L G ++ ECK G P P + WFK EL+P + ++
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 148 TNSL--GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
T L G Y C+A N G+A+ L V P F+ V
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDV------------------GSPPVFIQEPADVS 803
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYR-DDQPVDES--SRCHLGKEERGVFFLDIQALEFLD 262
+I V PEP++ W R D+ P+ S + + G F I L D
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF--ILNLWASD 861
Query: 263 QAEWKCVAFNDFG--QSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVI-G 318
+ + C A N FG QS T+ + L+ P P A + + + L C ++ G
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV-----ANVIEGQQLTLPCTLLAG 916
Query: 319 VPQPVLKWYKDGEEL---------KPGDIH-RIISGQDGTCSLGTYTCEASNCMGVAASS 368
P P +W K+ L G +H + QDG G YTC ASN G +
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG----GEYTCVASNVAGTNNKT 972
Query: 369 ASLL 372
S++
Sbjct: 973 TSVV 976
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 4149 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 4195
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 4196 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 4245
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 4246 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 4335
Score = 46.4 bits (105), Expect = 0.002
Identities = 68/283 (24%), Positives = 104/283 (36%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 4239
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 4240 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 4281
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 4282 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 4336
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
F+ + P +K + N L +N C+V G P P ++W + G +++
Sbjct: 4337 VKAIGFVYVKEPPVFKGD-YPSNWIEPLGGNAILN--CEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 4394 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 4377 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 4433 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488
Query: 342 IS 343
+S
Sbjct: 4489 LS 4490
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 3793 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 3891
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 3892 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 3947
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 4365 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 4423
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 4424 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 4475 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 4516
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 4444 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 4503
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 4504 TSEFECVARNLMG 4516
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 92.3 bits (219), Expect = 3e-17
Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 38/285 (13%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG--TNSLGS 153
+ ++T +S EC+V G P P ++W KDG L G + QL + G
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A N G +L+V + + +++P+ + SV K
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSVHAPPS---------IIGNHRSPENI----SVVEK--NSVS 2405
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T + + P PS+ W++D PV S+ + R L + D ++ CV N
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNA 2462
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G+ L +++P H LE+++ + ++ +V L C+V G P P + W+KDG+ L
Sbjct: 2463 AGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQPL 2520
Query: 334 KPGDIHRIISG----QDGTCSL---GTYTCEASNCMGVAASSASL 371
+ + H IISG Q + G YTC AS+ G + S SL
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 83.8 bits (198), Expect = 9e-15
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD + L +T N G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNR-G 1973
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1974 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
R + P PSL W +D PV SS + + G L + + + D + CVA N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 2088 AAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGHP 2143
Query: 333 L--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 2144 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 1450 VPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 1508 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 1562
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ + P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 1618
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LECK G P P+L W
Sbjct: 1619 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECKAAGNPSPILTWL 1676
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 1677 KDGVPVKANDNIRIEAG 1693
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT-----------NSLGSYCCIAKNCM 162
++ EC+ P+ LSW+KDGQ LK D + + G Y C+A N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G+ ++ ++ + +KL N +G ++ + I+ P + P
Sbjct: 2752 GEDELDFDVNIQVPPSF----QKLWEIG-NMLDTGRNG-EAKDVIINNPISLYCETNAAP 2805
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P+L WY+D P+ S + + R L I + D + CVA N+ G+
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+++++P K L +L ++ A+ +EC G P P W KDG+ L D H+
Sbjct: 2863 VRVLVPPIIKGANSDLPEEVTVLVNKSAL-IECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2921
Query: 342 ISG-------QDGTCSLGTYTCEASNCMGVA 365
+S +G Y C A N G A
Sbjct: 2922 LSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 78.6 bits (185), Expect = 3e-13
Identities = 83/306 (27%), Positives = 129/306 (42%), Gaps = 43/306 (14%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK- 138
S K N + VP + P+ ENL V+ +S C+V GFP P LSW K+ Q +K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPK-SENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 139 -------PGD-VYQL--TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQL 188
PG Q+ + G Y CIA N G++ LTV + + + + L
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESL 3066
Query: 189 FSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
N V SV + + A+PP P + WY++ + + ES+ + + +
Sbjct: 3067 SVVN-----VREGTSVSLECESN-------AVPP-PVITWYKNGRMITESTHVEILADGQ 3113
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG 308
L I+ E D ++ C A N G+ + L + +P + P E + +
Sbjct: 3114 ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISN 3167
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISG-------QDGTCSLGTYTCEAS 359
V L C G+P P + W K+ + ++ D RI+SG + G YTC AS
Sbjct: 3168 PVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS 3227
Query: 360 NCMGVA 365
N G A
Sbjct: 3228 NMEGKA 3233
Score = 77.8 bits (183), Expect = 6e-13
Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS EC+ P PV++W+K+G+ + ++ G I K
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 3119
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 3120 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 3292
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 74.1 bits (174), Expect = 7e-12
Identities = 76/283 (26%), Positives = 115/283 (40%), Gaps = 46/283 (16%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD---------VYQLTGTN--S 150
E + ++ + L+ EC G P P SW KDGQ L D + Q+ T
Sbjct: 2880 EEVTVLVNKSALI--ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD 2937
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKI 208
+G Y C+A+N G A L V P V G KS + +
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVH-------------------VPPSVIGPKSENLTVVV 2978
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+ T +V+ P P L W +++QP+ ++ + R L I + D E+ C
Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT---LQIIRAKVSDGGEYTC 3035
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
+A N G+S L + +P K E+L + EG +V+LEC+ VP PV+ WY
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3094
Query: 328 KDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
K+G + + + + GQ G Y C A N G
Sbjct: 3095 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 73.7 bits (173), Expect = 9e-12
Identities = 66/262 (25%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ EC+ G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 1617
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I K A P P L W
Sbjct: 1618 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 1676 LKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 1733 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAG 1812
Score = 72.9 bits (171), Expect = 2e-11
Identities = 70/278 (25%), Positives = 111/278 (39%), Gaps = 42/278 (15%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG-------TN----SLGSYCCIA 158
E+ V+ C+V G P P ++W KDGQ L+ + + + TN G Y C+A
Sbjct: 2493 EKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ G S S L V + + P+ V ++ P +
Sbjct: 2553 SSPAGHKSRSFSLNVF-------VSPTIAGVGSDGNPE------DVTVILNSPTSLVCEA 2599
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA-EWKCVAFNDFGQS 277
P ++ W++D P++ + + R + L+ Q D A + CVA N+ G+
Sbjct: 2600 YSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQE----DNAGRYSCVATNEAGEM 2655
Query: 278 VTSCFLKLIIPRHYKKPRF----LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ +K+ IP K L + + + LEC+ +P L WYKDG+ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
K D H I+ T + G YTC ASN G
Sbjct: 2716 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 3557
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 3614 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 3671
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAG 3699
Score = 69.7 bits (163), Expect = 2e-10
Identities = 70/275 (25%), Positives = 109/275 (39%), Gaps = 39/275 (14%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPG-DVYQLTGTNSL----------GSYCCIAKNCMG 163
S C+ +P ++WFKDG L+ ++ L G +L G Y C+A N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ E+ V I +N+ + L+ +PK V+ K++ + P
Sbjct: 2654 EMIKHYEVKVY-IPPIINKGD---LWGPGLSPK------EVKIKVNNTLTLECEAYAIPS 2703
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
SL WY+D QP+ H+ G L I+ + D + CVA N G+ +
Sbjct: 2704 ASLSWYKDGQPLKSDD--HVNIAANG-HTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760
Query: 284 KLIIPRHYKKPRFLENL-----QAILSD---EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ +P ++K + N+ D ++L C+ P P L WYKDG L
Sbjct: 2761 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMG 363
D I+ G + G YTC A N G
Sbjct: 2821 SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 68.9 bits (161), Expect = 3e-10
Identities = 81/287 (28%), Positives = 118/287 (41%), Gaps = 47/287 (16%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR 1804
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 1848
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 1849 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDGE 331
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 1906 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 332 ELKPGD----IHR--IISGQDGTCS-LGTYTCEASNCMGVAASSASL 371
L ++R II + S G Y C A N G SL
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSL 2006
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 3967 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 4008
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 4065
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 4066 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 4121
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 4122 SIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 68.1 bits (159), Expect = 5e-10
Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 45/290 (15%)
Query: 103 NLQAVLTEEGLVSFECKVVGFPTPVLSWFKDG----------QELKPGDVYQLTGT--NS 150
N+ AV+ V EC+ G P P L+W KDG Q L G + LT +
Sbjct: 2019 NMVAVVVNNP-VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISD 2077
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y C+A N G+ +L V N + EE+ + + ++VE
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLIS----------QAVELLCQS 2127
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
AIPP P+L W +D P+ + + E R V L I+ + D + C A
Sbjct: 2128 D-------AIPP-PTLTWLKDGHPLLKKPGLSIS-ENRSV--LKIEDAQVQDTGRYTCEA 2176
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G++ + + + +P + L L I + ++L C+ G+P P L W K G
Sbjct: 2177 TNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIWKKKG 2234
Query: 331 EEL---KPGDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
+ G + + G+ S+ Y+C ASN G A +L
Sbjct: 2235 SPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 67.7 bits (158), Expect = 6e-10
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 3224
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 3225 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3282
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 3283 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 3341
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L ++ + ++N+EC+ G P P + W K+G L G + R
Sbjct: 3342 IRGNKDEAEKLMTLV--DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 3399
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 3400 IVRAQ--VSDVAVYTCVASNRAGV 3421
Score = 66.1 bits (154), Expect = 2e-09
Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 1408
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-- 202
+ G+ S A Q N + + P + G
Sbjct: 1409 TVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 1460
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 1518
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LEC+ G+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPM 1576
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 64.1 bits (149), Expect = 8e-09
Identities = 75/295 (25%), Positives = 114/295 (38%), Gaps = 40/295 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLT 146
P Q + T EG+ V+ CK G P P + W K G+ + G +Y ++
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 1040
Query: 147 -GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G G Y C A N G A +LTV ++ L P + L E
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEE 1096
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
+ + ++PP P + W ++ Q + S H + I D
Sbjct: 1097 VTLPCEVK-----SLPP-PIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGM 1147
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ CVA N G + L + +P K R ++L+ + V++ C G P PV+
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVIT 1203
Query: 326 WYKDGEE-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
W K G L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 1204 WSKGGSTMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Score = 62.5 bits (145), Expect = 2e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 3299
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 3300 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 3354
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 3355 LVDTSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 3411
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 3412 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 3469
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 3470 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Score = 60.9 bits (141), Expect = 7e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 1248 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 1294
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 1295 KPTIKWLHNGRELT-GREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 1352
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 1353 LKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 58.0 bits (134), Expect = 5e-07
Identities = 68/271 (25%), Positives = 104/271 (38%), Gaps = 28/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
+S C+ P P L+W+KDG L D V L G G I + + A +
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPG----GRVLQIPRAKVEDAGRYTCVA 2850
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS-----VEAKIDEPFRFTIKVAIPPEPSLL 227
V + E+ LQ + P + G S V +++ + P P
Sbjct: 2851 VNEAG-----EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W +D QP+ E R L I + D + CVA N G + L + +
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Query: 288 PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG--- 344
P P+ ENL ++++ ++L C+V G P P L W K+ + +K I+ G
Sbjct: 2963 PPSVIGPKS-ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT 3019
Query: 345 ----QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A N G + SL
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 3609
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 3610 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 3663
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 3664 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 3720
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 3721 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 3774
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 3775 VTDTGRYLCMATNAAG 3790
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/270 (22%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C G+P P ++W + + Y++T +L KN A A +
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL-----FIKNA---APKDAGIYG 680
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +++ +APK + + + + K + P P + W++ D
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ S+ + + + L IQ + LD ++ CVA N+ G++ L + P
Sbjct: 741 ELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP----- 792
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYK-DGEEL--KPGDIHRIISGQDGTC 349
P F++ + + G+ V L C V G P+P +KW + D + +P + I + G
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
+ GTY CEA N G S ++
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTV 882
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 4068
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 4069 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 4110
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 4167 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 4221
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 4222 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 3694
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 3695 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 3750
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 3751 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3808
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 3809 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 3844
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 1157 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 1255
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 1256 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 1307
Score = 48.8 bits (111), Expect = 3e-04
Identities = 79/304 (25%), Positives = 116/304 (38%), Gaps = 58/304 (19%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ M +L G ++ ECK G P P + WFK EL+P + ++
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 148 TNSL--GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
T L G Y C+A N G+A+ L V P F+ V
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDV------------------GSPPVFIQEPADVS 803
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYR-DDQPVDES--SRCHLGKEERGVFFLDIQALEFLD 262
+I V PEP++ W R D+ P+ S + + G F I L D
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF--ILNLWASD 861
Query: 263 QAEWKCVAFNDFG--QSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVI-G 318
+ + C A N FG QS T+ + L+ P P A + + + L C ++ G
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV-----ANVIEGQQLTLPCTLLAG 916
Query: 319 VPQPVLKWYKDGEEL---------KPGDIH-RIISGQDGTCSLGTYTCEASNCMGVAASS 368
P P +W K+ L G +H + QDG G YTC ASN G +
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG----GEYTCVASNVAGTNNKT 972
Query: 369 ASLL 372
S++
Sbjct: 973 TSVV 976
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 4149 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 4195
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 4196 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 4245
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 4246 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 4335
Score = 46.4 bits (105), Expect = 0.002
Identities = 68/283 (24%), Positives = 104/283 (36%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 4239
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 4240 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 4281
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 4282 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 4336
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
F+ + P +K + N L +N C+V G P P ++W + G +++
Sbjct: 4337 VKAIGFVYVKEPPVFKGD-YPSNWIEPLGGNAILN--CEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 4394 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 4377 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 4433 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488
Query: 342 IS 343
+S
Sbjct: 4489 LS 4490
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 3793 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 3891
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 3892 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 3947
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 4365 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 4423
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 4424 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 4475 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 4516
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 4444 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 4503
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 4504 TSEFECVARNLMG 4516
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 92.3 bits (219), Expect = 3e-17
Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 38/285 (13%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG--TNSLGS 153
+ ++T +S EC+V G P P ++W KDG L G + QL + G
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A N G +L+V + + +++P+ + SV K
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSVHAPPS---------IIGNHRSPENI----SVVEK--NSVS 2405
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T + + P PS+ W++D PV S+ + R L + D ++ CV N
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNA 2462
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G+ L +++P H LE+++ + ++ +V L C+V G P P + W+KDG+ L
Sbjct: 2463 AGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQPL 2520
Query: 334 KPGDIHRIISG----QDGTCSL---GTYTCEASNCMGVAASSASL 371
+ + H IISG Q + G YTC AS+ G + S SL
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 83.8 bits (198), Expect = 9e-15
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD + L +T N G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNR-G 1973
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1974 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
R + P PSL W +D PV SS + + G L + + + D + CVA N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 2088 AAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGHP 2143
Query: 333 L--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 2144 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 1450 VPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 1508 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 1562
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ + P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 1618
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LECK G P P+L W
Sbjct: 1619 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECKAAGNPSPILTWL 1676
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 1677 KDGVPVKANDNIRIEAG 1693
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT-----------NSLGSYCCIAKNCM 162
++ EC+ P+ LSW+KDGQ LK D + + G Y C+A N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G+ ++ ++ + +KL N +G ++ + I+ P + P
Sbjct: 2752 GEDELDFDVNIQVPPSF----QKLWEIG-NMLDTGRNG-EAKDVIINNPISLYCETNAAP 2805
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P+L WY+D P+ S + + R L I + D + CVA N+ G+
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+++++P K L +L ++ A+ +EC G P P W KDG+ L D H+
Sbjct: 2863 VRVLVPPIIKGANSDLPEEVTVLVNKSAL-IECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2921
Query: 342 ISG-------QDGTCSLGTYTCEASNCMGVA 365
+S +G Y C A N G A
Sbjct: 2922 LSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 78.6 bits (185), Expect = 3e-13
Identities = 83/306 (27%), Positives = 129/306 (42%), Gaps = 43/306 (14%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK- 138
S K N + VP + P+ ENL V+ +S C+V GFP P LSW K+ Q +K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPK-SENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 139 -------PGD-VYQL--TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQL 188
PG Q+ + G Y CIA N G++ LTV + + + + L
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESL 3066
Query: 189 FSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
N V SV + + A+PP P + WY++ + + ES+ + + +
Sbjct: 3067 SVVN-----VREGTSVSLECESN-------AVPP-PVITWYKNGRMITESTHVEILADGQ 3113
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG 308
L I+ E D ++ C A N G+ + L + +P + P E + +
Sbjct: 3114 ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISN 3167
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISG-------QDGTCSLGTYTCEAS 359
V L C G+P P + W K+ + ++ D RI+SG + G YTC AS
Sbjct: 3168 PVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS 3227
Query: 360 NCMGVA 365
N G A
Sbjct: 3228 NMEGKA 3233
Score = 77.8 bits (183), Expect = 6e-13
Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS EC+ P PV++W+K+G+ + ++ G I K
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 3119
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 3120 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 3292
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 74.1 bits (174), Expect = 7e-12
Identities = 76/283 (26%), Positives = 115/283 (40%), Gaps = 46/283 (16%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD---------VYQLTGTN--S 150
E + ++ + L+ EC G P P SW KDGQ L D + Q+ T
Sbjct: 2880 EEVTVLVNKSALI--ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD 2937
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKI 208
+G Y C+A+N G A L V P V G KS + +
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVH-------------------VPPSVIGPKSENLTVVV 2978
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+ T +V+ P P L W +++QP+ ++ + R L I + D E+ C
Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT---LQIIRAKVSDGGEYTC 3035
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
+A N G+S L + +P K E+L + EG +V+LEC+ VP PV+ WY
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3094
Query: 328 KDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
K+G + + + + GQ G Y C A N G
Sbjct: 3095 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 73.7 bits (173), Expect = 9e-12
Identities = 66/262 (25%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ EC+ G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 1617
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I K A P P L W
Sbjct: 1618 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 1676 LKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 1733 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAG 1812
Score = 72.9 bits (171), Expect = 2e-11
Identities = 70/278 (25%), Positives = 111/278 (39%), Gaps = 42/278 (15%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG-------TN----SLGSYCCIA 158
E+ V+ C+V G P P ++W KDGQ L+ + + + TN G Y C+A
Sbjct: 2493 EKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ G S S L V + + P+ V ++ P +
Sbjct: 2553 SSPAGHKSRSFSLNVF-------VSPTIAGVGSDGNPE------DVTVILNSPTSLVCEA 2599
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA-EWKCVAFNDFGQS 277
P ++ W++D P++ + + R + L+ Q D A + CVA N+ G+
Sbjct: 2600 YSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQE----DNAGRYSCVATNEAGEM 2655
Query: 278 VTSCFLKLIIPRHYKKPRF----LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ +K+ IP K L + + + LEC+ +P L WYKDG+ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
K D H I+ T + G YTC ASN G
Sbjct: 2716 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 3557
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 3614 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 3671
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAG 3699
Score = 69.7 bits (163), Expect = 2e-10
Identities = 70/275 (25%), Positives = 109/275 (39%), Gaps = 39/275 (14%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPG-DVYQLTGTNSL----------GSYCCIAKNCMG 163
S C+ +P ++WFKDG L+ ++ L G +L G Y C+A N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ E+ V I +N+ + L+ +PK V+ K++ + P
Sbjct: 2654 EMIKHYEVKVY-IPPIINKGD---LWGPGLSPK------EVKIKVNNTLTLECEAYAIPS 2703
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
SL WY+D QP+ H+ G L I+ + D + CVA N G+ +
Sbjct: 2704 ASLSWYKDGQPLKSDD--HVNIAANG-HTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760
Query: 284 KLIIPRHYKKPRFLENL-----QAILSD---EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ +P ++K + N+ D ++L C+ P P L WYKDG L
Sbjct: 2761 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMG 363
D I+ G + G YTC A N G
Sbjct: 2821 SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 68.9 bits (161), Expect = 3e-10
Identities = 81/287 (28%), Positives = 118/287 (41%), Gaps = 47/287 (16%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR 1804
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 1848
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 1849 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDGE 331
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 1906 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 332 ELKPGD----IHR--IISGQDGTCS-LGTYTCEASNCMGVAASSASL 371
L ++R II + S G Y C A N G SL
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSL 2006
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 3967 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 4008
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 4065
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 4066 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 4121
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 4122 SIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 68.1 bits (159), Expect = 5e-10
Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 45/290 (15%)
Query: 103 NLQAVLTEEGLVSFECKVVGFPTPVLSWFKDG----------QELKPGDVYQLTGT--NS 150
N+ AV+ V EC+ G P P L+W KDG Q L G + LT +
Sbjct: 2019 NMVAVVVNNP-VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISD 2077
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y C+A N G+ +L V N + EE+ + + ++VE
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLIS----------QAVELLCQS 2127
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
AIPP P+L W +D P+ + + E R V L I+ + D + C A
Sbjct: 2128 D-------AIPP-PTLTWLKDGHPLLKKPGLSIS-ENRSV--LKIEDAQVQDTGRYTCEA 2176
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G++ + + + +P + L L I + ++L C+ G+P P L W K G
Sbjct: 2177 TNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIWKKKG 2234
Query: 331 EEL---KPGDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
+ G + + G+ S+ Y+C ASN G A +L
Sbjct: 2235 SPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 67.7 bits (158), Expect = 6e-10
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 3224
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 3225 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3282
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 3283 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 3341
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L ++ + ++N+EC+ G P P + W K+G L G + R
Sbjct: 3342 IRGNKDEAEKLMTLV--DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 3399
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 3400 IVRAQ--VSDVAVYTCVASNRAGV 3421
Score = 66.1 bits (154), Expect = 2e-09
Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 1408
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-- 202
+ G+ S A Q N + + P + G
Sbjct: 1409 TVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 1460
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 1518
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LEC+ G+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPM 1576
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 64.1 bits (149), Expect = 8e-09
Identities = 75/295 (25%), Positives = 114/295 (38%), Gaps = 40/295 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLT 146
P Q + T EG+ V+ CK G P P + W K G+ + G +Y ++
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 1040
Query: 147 -GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G G Y C A N G A +LTV ++ L P + L E
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEE 1096
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
+ + ++PP P + W ++ Q + S H + I D
Sbjct: 1097 VTLPCEVK-----SLPP-PIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGM 1147
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ CVA N G + L + +P K R ++L+ + V++ C G P PV+
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVIT 1203
Query: 326 WYKDGEE-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
W K G L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 1204 WSKGGSTMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Score = 62.5 bits (145), Expect = 2e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 3299
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 3300 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 3354
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 3355 LVDTSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 3411
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 3412 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 3469
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 3470 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Score = 60.9 bits (141), Expect = 7e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 1248 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 1294
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 1295 KPTIKWLHNGRELT-GREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 1352
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 1353 LKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 58.0 bits (134), Expect = 5e-07
Identities = 68/271 (25%), Positives = 104/271 (38%), Gaps = 28/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
+S C+ P P L+W+KDG L D V L G G I + + A +
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPG----GRVLQIPRAKVEDAGRYTCVA 2850
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS-----VEAKIDEPFRFTIKVAIPPEPSLL 227
V + E+ LQ + P + G S V +++ + P P
Sbjct: 2851 VNEAG-----EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W +D QP+ E R L I + D + CVA N G + L + +
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Query: 288 PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG--- 344
P P+ ENL ++++ ++L C+V G P P L W K+ + +K I+ G
Sbjct: 2963 PPSVIGPKS-ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT 3019
Query: 345 ----QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A N G + SL
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 3609
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 3610 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 3663
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 3664 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 3720
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 3721 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 3774
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 3775 VTDTGRYLCMATNAAG 3790
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/270 (22%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C G+P P ++W + + Y++T +L KN A A +
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL-----FIKNA---APKDAGIYG 680
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +++ +APK + + + + K + P P + W++ D
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ S+ + + + L IQ + LD ++ CVA N+ G++ L + P
Sbjct: 741 ELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP----- 792
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYK-DGEEL--KPGDIHRIISGQDGTC 349
P F++ + + G+ V L C V G P+P +KW + D + +P + I + G
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
+ GTY CEA N G S ++
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTV 882
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 4068
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 4069 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 4110
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 4167 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 4221
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 4222 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 3694
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 3695 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 3750
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 3751 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3808
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 3809 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 3844
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 1157 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 1255
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 1256 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 1307
Score = 48.8 bits (111), Expect = 3e-04
Identities = 79/304 (25%), Positives = 116/304 (38%), Gaps = 58/304 (19%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ M +L G ++ ECK G P P + WFK EL+P + ++
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 148 TNSL--GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
T L G Y C+A N G+A+ L V P F+ V
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDV------------------GSPPVFIQEPADVS 803
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYR-DDQPVDES--SRCHLGKEERGVFFLDIQALEFLD 262
+I V PEP++ W R D+ P+ S + + G F I L D
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF--ILNLWASD 861
Query: 263 QAEWKCVAFNDFG--QSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVI-G 318
+ + C A N FG QS T+ + L+ P P A + + + L C ++ G
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV-----ANVIEGQQLTLPCTLLAG 916
Query: 319 VPQPVLKWYKDGEEL---------KPGDIH-RIISGQDGTCSLGTYTCEASNCMGVAASS 368
P P +W K+ L G +H + QDG G YTC ASN G +
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG----GEYTCVASNVAGTNNKT 972
Query: 369 ASLL 372
S++
Sbjct: 973 TSVV 976
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 4149 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 4195
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 4196 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 4245
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 4246 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 4335
Score = 46.4 bits (105), Expect = 0.002
Identities = 68/283 (24%), Positives = 104/283 (36%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 4239
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 4240 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 4281
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 4282 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 4336
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
F+ + P +K + N L +N C+V G P P ++W + G +++
Sbjct: 4337 VKAIGFVYVKEPPVFKGD-YPSNWIEPLGGNAILN--CEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 4394 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 4377 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 4433 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488
Query: 342 IS 343
+S
Sbjct: 4489 LS 4490
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 3793 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 3891
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 3892 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 3947
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 4365 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 4423
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 4424 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 4475 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 4516
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 4444 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 4503
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 4504 TSEFECVARNLMG 4516
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 92.3 bits (219), Expect = 3e-17
Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 38/285 (13%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG--TNSLGS 153
+ ++T +S EC+V G P P ++W KDG L G + QL + G
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A N G +L+V + + +++P+ + SV K
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSVHAPPS---------IIGNHRSPENI----SVVEK--NSVS 2405
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T + + P PS+ W++D PV S+ + R L + D ++ CV N
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNA 2462
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G+ L +++P H LE+++ + ++ +V L C+V G P P + W+KDG+ L
Sbjct: 2463 AGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQPL 2520
Query: 334 KPGDIHRIISG----QDGTCSL---GTYTCEASNCMGVAASSASL 371
+ + H IISG Q + G YTC AS+ G + S SL
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 83.8 bits (198), Expect = 9e-15
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD + L +T N G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNR-G 1973
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1974 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
R + P PSL W +D PV SS + + G L + + + D + CVA N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 2088 AAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGHP 2143
Query: 333 L--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 2144 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 1450 VPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 1508 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 1562
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ + P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 1618
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LECK G P P+L W
Sbjct: 1619 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECKAAGNPSPILTWL 1676
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 1677 KDGVPVKANDNIRIEAG 1693
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT-----------NSLGSYCCIAKNCM 162
++ EC+ P+ LSW+KDGQ LK D + + G Y C+A N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G+ ++ ++ + +KL N +G ++ + I+ P + P
Sbjct: 2752 GEDELDFDVNIQVPPSF----QKLWEIG-NMLDTGRNG-EAKDVIINNPISLYCETNAAP 2805
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P+L WY+D P+ S + + R L I + D + CVA N+ G+
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+++++P K L +L ++ A+ +EC G P P W KDG+ L D H+
Sbjct: 2863 VRVLVPPIIKGANSDLPEEVTVLVNKSAL-IECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2921
Query: 342 ISG-------QDGTCSLGTYTCEASNCMGVA 365
+S +G Y C A N G A
Sbjct: 2922 LSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 78.6 bits (185), Expect = 3e-13
Identities = 83/306 (27%), Positives = 129/306 (42%), Gaps = 43/306 (14%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK- 138
S K N + VP + P+ ENL V+ +S C+V GFP P LSW K+ Q +K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPK-SENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 139 -------PGD-VYQL--TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQL 188
PG Q+ + G Y CIA N G++ LTV + + + + L
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESL 3066
Query: 189 FSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
N V SV + + A+PP P + WY++ + + ES+ + + +
Sbjct: 3067 SVVN-----VREGTSVSLECESN-------AVPP-PVITWYKNGRMITESTHVEILADGQ 3113
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG 308
L I+ E D ++ C A N G+ + L + +P + P E + +
Sbjct: 3114 ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISN 3167
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISG-------QDGTCSLGTYTCEAS 359
V L C G+P P + W K+ + ++ D RI+SG + G YTC AS
Sbjct: 3168 PVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS 3227
Query: 360 NCMGVA 365
N G A
Sbjct: 3228 NMEGKA 3233
Score = 77.8 bits (183), Expect = 6e-13
Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS EC+ P PV++W+K+G+ + ++ G I K
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 3119
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 3120 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 3292
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 74.1 bits (174), Expect = 7e-12
Identities = 76/283 (26%), Positives = 115/283 (40%), Gaps = 46/283 (16%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD---------VYQLTGTN--S 150
E + ++ + L+ EC G P P SW KDGQ L D + Q+ T
Sbjct: 2880 EEVTVLVNKSALI--ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD 2937
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKI 208
+G Y C+A+N G A L V P V G KS + +
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVH-------------------VPPSVIGPKSENLTVVV 2978
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+ T +V+ P P L W +++QP+ ++ + R L I + D E+ C
Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT---LQIIRAKVSDGGEYTC 3035
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
+A N G+S L + +P K E+L + EG +V+LEC+ VP PV+ WY
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3094
Query: 328 KDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
K+G + + + + GQ G Y C A N G
Sbjct: 3095 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 73.7 bits (173), Expect = 9e-12
Identities = 66/262 (25%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ EC+ G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 1617
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I K A P P L W
Sbjct: 1618 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 1676 LKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 1733 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAG 1812
Score = 72.9 bits (171), Expect = 2e-11
Identities = 70/278 (25%), Positives = 111/278 (39%), Gaps = 42/278 (15%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG-------TN----SLGSYCCIA 158
E+ V+ C+V G P P ++W KDGQ L+ + + + TN G Y C+A
Sbjct: 2493 EKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ G S S L V + + P+ V ++ P +
Sbjct: 2553 SSPAGHKSRSFSLNVF-------VSPTIAGVGSDGNPE------DVTVILNSPTSLVCEA 2599
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA-EWKCVAFNDFGQS 277
P ++ W++D P++ + + R + L+ Q D A + CVA N+ G+
Sbjct: 2600 YSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQE----DNAGRYSCVATNEAGEM 2655
Query: 278 VTSCFLKLIIPRHYKKPRF----LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ +K+ IP K L + + + LEC+ +P L WYKDG+ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
K D H I+ T + G YTC ASN G
Sbjct: 2716 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 3557
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 3614 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 3671
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAG 3699
Score = 69.7 bits (163), Expect = 2e-10
Identities = 70/275 (25%), Positives = 109/275 (39%), Gaps = 39/275 (14%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPG-DVYQLTGTNSL----------GSYCCIAKNCMG 163
S C+ +P ++WFKDG L+ ++ L G +L G Y C+A N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ E+ V I +N+ + L+ +PK V+ K++ + P
Sbjct: 2654 EMIKHYEVKVY-IPPIINKGD---LWGPGLSPK------EVKIKVNNTLTLECEAYAIPS 2703
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
SL WY+D QP+ H+ G L I+ + D + CVA N G+ +
Sbjct: 2704 ASLSWYKDGQPLKSDD--HVNIAANG-HTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760
Query: 284 KLIIPRHYKKPRFLENL-----QAILSD---EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ +P ++K + N+ D ++L C+ P P L WYKDG L
Sbjct: 2761 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMG 363
D I+ G + G YTC A N G
Sbjct: 2821 SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 68.9 bits (161), Expect = 3e-10
Identities = 81/287 (28%), Positives = 118/287 (41%), Gaps = 47/287 (16%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR 1804
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 1848
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 1849 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDGE 331
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 1906 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 332 ELKPGD----IHR--IISGQDGTCS-LGTYTCEASNCMGVAASSASL 371
L ++R II + S G Y C A N G SL
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSL 2006
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 3967 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 4008
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 4065
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 4066 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 4121
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 4122 SIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 68.1 bits (159), Expect = 5e-10
Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 45/290 (15%)
Query: 103 NLQAVLTEEGLVSFECKVVGFPTPVLSWFKDG----------QELKPGDVYQLTGT--NS 150
N+ AV+ V EC+ G P P L+W KDG Q L G + LT +
Sbjct: 2019 NMVAVVVNNP-VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISD 2077
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y C+A N G+ +L V N + EE+ + + ++VE
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLIS----------QAVELLCQS 2127
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
AIPP P+L W +D P+ + + E R V L I+ + D + C A
Sbjct: 2128 D-------AIPP-PTLTWLKDGHPLLKKPGLSIS-ENRSV--LKIEDAQVQDTGRYTCEA 2176
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G++ + + + +P + L L I + ++L C+ G+P P L W K G
Sbjct: 2177 TNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIWKKKG 2234
Query: 331 EEL---KPGDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
+ G + + G+ S+ Y+C ASN G A +L
Sbjct: 2235 SPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 67.7 bits (158), Expect = 6e-10
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 3224
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 3225 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3282
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 3283 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 3341
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L ++ + ++N+EC+ G P P + W K+G L G + R
Sbjct: 3342 IRGNKDEAEKLMTLV--DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 3399
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 3400 IVRAQ--VSDVAVYTCVASNRAGV 3421
Score = 66.1 bits (154), Expect = 2e-09
Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 1408
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-- 202
+ G+ S A Q N + + P + G
Sbjct: 1409 TVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 1460
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 1518
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LEC+ G+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPM 1576
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 64.1 bits (149), Expect = 8e-09
Identities = 75/295 (25%), Positives = 114/295 (38%), Gaps = 40/295 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLT 146
P Q + T EG+ V+ CK G P P + W K G+ + G +Y ++
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 1040
Query: 147 -GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G G Y C A N G A +LTV ++ L P + L E
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEE 1096
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
+ + ++PP P + W ++ Q + S H + I D
Sbjct: 1097 VTLPCEVK-----SLPP-PIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGM 1147
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ CVA N G + L + +P K R ++L+ + V++ C G P PV+
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVIT 1203
Query: 326 WYKDGEE-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
W K G L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 1204 WSKGGSTMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Score = 62.5 bits (145), Expect = 2e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 3299
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 3300 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 3354
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 3355 LVDTSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 3411
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 3412 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 3469
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 3470 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Score = 60.9 bits (141), Expect = 7e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 1248 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 1294
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 1295 KPTIKWLHNGRELT-GREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 1352
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 1353 LKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 58.0 bits (134), Expect = 5e-07
Identities = 68/271 (25%), Positives = 104/271 (38%), Gaps = 28/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
+S C+ P P L+W+KDG L D V L G G I + + A +
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPG----GRVLQIPRAKVEDAGRYTCVA 2850
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS-----VEAKIDEPFRFTIKVAIPPEPSLL 227
V + E+ LQ + P + G S V +++ + P P
Sbjct: 2851 VNEAG-----EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W +D QP+ E R L I + D + CVA N G + L + +
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Query: 288 PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG--- 344
P P+ ENL ++++ ++L C+V G P P L W K+ + +K I+ G
Sbjct: 2963 PPSVIGPKS-ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT 3019
Query: 345 ----QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A N G + SL
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 3609
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 3610 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 3663
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 3664 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 3720
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 3721 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 3774
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 3775 VTDTGRYLCMATNAAG 3790
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/270 (22%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C G+P P ++W + + Y++T +L KN A A +
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL-----FIKNA---APKDAGIYG 680
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +++ +APK + + + + K + P P + W++ D
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ S+ + + + L IQ + LD ++ CVA N+ G++ L + P
Sbjct: 741 ELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP----- 792
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYK-DGEEL--KPGDIHRIISGQDGTC 349
P F++ + + G+ V L C V G P+P +KW + D + +P + I + G
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
+ GTY CEA N G S ++
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTV 882
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 4068
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 4069 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 4110
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 4167 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 4221
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 4222 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 3694
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 3695 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 3750
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 3751 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3808
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 3809 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 3844
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 1157 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 1255
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 1256 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 1307
Score = 48.8 bits (111), Expect = 3e-04
Identities = 79/304 (25%), Positives = 116/304 (38%), Gaps = 58/304 (19%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ M +L G ++ ECK G P P + WFK EL+P + ++
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 148 TNSL--GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
T L G Y C+A N G+A+ L V P F+ V
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDV------------------GSPPVFIQEPADVS 803
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYR-DDQPVDES--SRCHLGKEERGVFFLDIQALEFLD 262
+I V PEP++ W R D+ P+ S + + G F I L D
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF--ILNLWASD 861
Query: 263 QAEWKCVAFNDFG--QSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVI-G 318
+ + C A N FG QS T+ + L+ P P A + + + L C ++ G
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV-----ANVIEGQQLTLPCTLLAG 916
Query: 319 VPQPVLKWYKDGEEL---------KPGDIH-RIISGQDGTCSLGTYTCEASNCMGVAASS 368
P P +W K+ L G +H + QDG G YTC ASN G +
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG----GEYTCVASNVAGTNNKT 972
Query: 369 ASLL 372
S++
Sbjct: 973 TSVV 976
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 4149 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 4195
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 4196 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 4245
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 4246 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 4335
Score = 46.4 bits (105), Expect = 0.002
Identities = 68/283 (24%), Positives = 104/283 (36%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 4239
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 4240 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 4281
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 4282 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 4336
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
F+ + P +K + N L +N C+V G P P ++W + G +++
Sbjct: 4337 VKAIGFVYVKEPPVFKGD-YPSNWIEPLGGNAILN--CEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 4394 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 4377 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 4433 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488
Query: 342 IS 343
+S
Sbjct: 4489 LS 4490
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 3793 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 3891
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 3892 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 3947
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 4365 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 4423
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 4424 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 4475 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 4516
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 4444 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 4503
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 4504 TSEFECVARNLMG 4516
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 92.3 bits (219), Expect = 3e-17
Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 38/285 (13%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG--TNSLGS 153
+ ++T +S EC+V G P P ++W KDG L G + QL + G
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A N G +L+V + + +++P+ + SV K
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSVHAPPS---------IIGNHRSPENI----SVVEK--NSVS 2405
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T + + P PS+ W++D PV S+ + R L + D ++ CV N
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNA 2462
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G+ L +++P H LE+++ + ++ +V L C+V G P P + W+KDG+ L
Sbjct: 2463 AGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQPL 2520
Query: 334 KPGDIHRIISG----QDGTCSL---GTYTCEASNCMGVAASSASL 371
+ + H IISG Q + G YTC AS+ G + S SL
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 83.8 bits (198), Expect = 9e-15
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD + L +T N G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNR-G 1973
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1974 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
R + P PSL W +D PV SS + + G L + + + D + CVA N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 2088 AAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGHP 2143
Query: 333 L--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 2144 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 1450 VPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 1508 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 1562
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ + P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 1618
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LECK G P P+L W
Sbjct: 1619 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECKAAGNPSPILTWL 1676
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 1677 KDGVPVKANDNIRIEAG 1693
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT-----------NSLGSYCCIAKNCM 162
++ EC+ P+ LSW+KDGQ LK D + + G Y C+A N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G+ ++ ++ + +KL N +G ++ + I+ P + P
Sbjct: 2752 GEDELDFDVNIQVPPSF----QKLWEIG-NMLDTGRNG-EAKDVIINNPISLYCETNAAP 2805
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P+L WY+D P+ S + + R L I + D + CVA N+ G+
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2862
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+++++P K L +L ++ A+ +EC G P P W KDG+ L D H+
Sbjct: 2863 VRVLVPPIIKGANSDLPEEVTVLVNKSAL-IECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2921
Query: 342 ISG-------QDGTCSLGTYTCEASNCMGVA 365
+S +G Y C A N G A
Sbjct: 2922 LSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 78.6 bits (185), Expect = 3e-13
Identities = 83/306 (27%), Positives = 129/306 (42%), Gaps = 43/306 (14%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK- 138
S K N + VP + P+ ENL V+ +S C+V GFP P LSW K+ Q +K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPK-SENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 139 -------PGD-VYQL--TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQL 188
PG Q+ + G Y CIA N G++ LTV + + + + L
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESL 3066
Query: 189 FSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
N V SV + + A+PP P + WY++ + + ES+ + + +
Sbjct: 3067 SVVN-----VREGTSVSLECESN-------AVPP-PVITWYKNGRMITESTHVEILADGQ 3113
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG 308
L I+ E D ++ C A N G+ + L + +P + P E + +
Sbjct: 3114 ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISN 3167
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISG-------QDGTCSLGTYTCEAS 359
V L C G+P P + W K+ + ++ D RI+SG + G YTC AS
Sbjct: 3168 PVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS 3227
Query: 360 NCMGVA 365
N G A
Sbjct: 3228 NMEGKA 3233
Score = 77.8 bits (183), Expect = 6e-13
Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS EC+ P PV++W+K+G+ + ++ G I K
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 3119
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 3120 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 3292
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 74.1 bits (174), Expect = 7e-12
Identities = 76/283 (26%), Positives = 115/283 (40%), Gaps = 46/283 (16%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD---------VYQLTGTN--S 150
E + ++ + L+ EC G P P SW KDGQ L D + Q+ T
Sbjct: 2880 EEVTVLVNKSALI--ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD 2937
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKI 208
+G Y C+A+N G A L V P V G KS + +
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVH-------------------VPPSVIGPKSENLTVVV 2978
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+ T +V+ P P L W +++QP+ ++ + R L I + D E+ C
Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT---LQIIRAKVSDGGEYTC 3035
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
+A N G+S L + +P K E+L + EG +V+LEC+ VP PV+ WY
Sbjct: 3036 IAINQAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3094
Query: 328 KDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
K+G + + + + GQ G Y C A N G
Sbjct: 3095 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 73.7 bits (173), Expect = 9e-12
Identities = 66/262 (25%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ EC+ G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 1617
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I K A P P L W
Sbjct: 1618 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 1676 LKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 1733 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAG 1812
Score = 72.9 bits (171), Expect = 2e-11
Identities = 70/278 (25%), Positives = 111/278 (39%), Gaps = 42/278 (15%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG-------TN----SLGSYCCIA 158
E+ V+ C+V G P P ++W KDGQ L+ + + + TN G Y C+A
Sbjct: 2493 EKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ G S S L V + + P+ V ++ P +
Sbjct: 2553 SSPAGHKSRSFSLNVF-------VSPTIAGVGSDGNPE------DVTVILNSPTSLVCEA 2599
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA-EWKCVAFNDFGQS 277
P ++ W++D P++ + + R + L+ Q D A + CVA N+ G+
Sbjct: 2600 YSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQE----DNAGRYSCVATNEAGEM 2655
Query: 278 VTSCFLKLIIPRHYKKPRF----LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ +K+ IP K L + + + LEC+ +P L WYKDG+ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
K D H I+ T + G YTC ASN G
Sbjct: 2716 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 3514 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 3557
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 3558 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3613
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 3614 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 3671
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAG 3699
Score = 69.7 bits (163), Expect = 2e-10
Identities = 70/275 (25%), Positives = 109/275 (39%), Gaps = 39/275 (14%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPG-DVYQLTGTNSL----------GSYCCIAKNCMG 163
S C+ +P ++WFKDG L+ ++ L G +L G Y C+A N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ E+ V I +N+ + L+ +PK V+ K++ + P
Sbjct: 2654 EMIKHYEVKVY-IPPIINKGD---LWGPGLSPK------EVKIKVNNTLTLECEAYAIPS 2703
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
SL WY+D QP+ H+ G L I+ + D + CVA N G+ +
Sbjct: 2704 ASLSWYKDGQPLKSDD--HVNIAANG-HTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2760
Query: 284 KLIIPRHYKKPRFLENL-----QAILSD---EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ +P ++K + N+ D ++L C+ P P L WYKDG L
Sbjct: 2761 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMG 363
D I+ G + G YTC A N G
Sbjct: 2821 SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 68.9 bits (161), Expect = 3e-10
Identities = 81/287 (28%), Positives = 118/287 (41%), Gaps = 47/287 (16%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR 1804
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 1848
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 1849 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDGE 331
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 1906 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959
Query: 332 ELKPGD----IHR--IISGQDGTCS-LGTYTCEASNCMGVAASSASL 371
L ++R II + S G Y C A N G SL
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSL 2006
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 3907 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3966
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 3967 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 4008
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 4065
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 4066 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 4121
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 4122 SIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 68.1 bits (159), Expect = 5e-10
Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 45/290 (15%)
Query: 103 NLQAVLTEEGLVSFECKVVGFPTPVLSWFKDG----------QELKPGDVYQLTGT--NS 150
N+ AV+ V EC+ G P P L+W KDG Q L G + LT +
Sbjct: 2019 NMVAVVVNNP-VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISD 2077
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y C+A N G+ +L V N + EE+ + + ++VE
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLIS----------QAVELLCQS 2127
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
AIPP P+L W +D P+ + + E R V L I+ + D + C A
Sbjct: 2128 D-------AIPP-PTLTWLKDGHPLLKKPGLSIS-ENRSV--LKIEDAQVQDTGRYTCEA 2176
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G++ + + + +P + L L I + ++L C+ G+P P L W K G
Sbjct: 2177 TNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIWKKKG 2234
Query: 331 EEL---KPGDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
+ G + + G+ S+ Y+C ASN G A +L
Sbjct: 2235 SPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 67.7 bits (158), Expect = 6e-10
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 3224
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 3225 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3282
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 3283 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 3341
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L ++ + ++N+EC+ G P P + W K+G L G + R
Sbjct: 3342 IRGNKDEAEKLMTLV--DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 3399
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 3400 IVRAQ--VSDVAVYTCVASNRAGV 3421
Score = 66.1 bits (154), Expect = 2e-09
Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 1408
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-- 202
+ G+ S A Q N + + P + G
Sbjct: 1409 TVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 1460
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 1518
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LEC+ G+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPM 1576
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 64.1 bits (149), Expect = 8e-09
Identities = 75/295 (25%), Positives = 114/295 (38%), Gaps = 40/295 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLT 146
P Q + T EG+ V+ CK G P P + W K G+ + G +Y ++
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 1040
Query: 147 -GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G G Y C A N G A +LTV ++ L P + L E
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEE 1096
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
+ + ++PP P + W ++ Q + S H + I D
Sbjct: 1097 VTLPCEVK-----SLPP-PIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGM 1147
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ CVA N G + L + +P K R ++L+ + V++ C G P PV+
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVIT 1203
Query: 326 WYKDGEE-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
W K G L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 1204 WSKGGSTMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Score = 62.5 bits (145), Expect = 2e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 3299
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 3300 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 3354
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 3355 LVDTSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 3411
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 3412 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 3469
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 3470 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Score = 60.9 bits (141), Expect = 7e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 1248 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 1294
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 1295 KPTIKWLHNGRELT-GREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 1352
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 1353 LKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 58.0 bits (134), Expect = 5e-07
Identities = 68/271 (25%), Positives = 104/271 (38%), Gaps = 28/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
+S C+ P P L+W+KDG L D V L G G I + + A +
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPG----GRVLQIPRAKVEDAGRYTCVA 2850
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS-----VEAKIDEPFRFTIKVAIPPEPSLL 227
V + E+ LQ + P + G S V +++ + P P
Sbjct: 2851 VNEAG-----EDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W +D QP+ E R L I + D + CVA N G + L + +
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Query: 288 PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG--- 344
P P+ ENL ++++ ++L C+V G P P L W K+ + +K I+ G
Sbjct: 2963 PPSVIGPKS-ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT 3019
Query: 345 ----QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A N G + SL
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 3609
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 3610 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 3663
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 3664 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 3720
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 3721 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 3774
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 3775 VTDTGRYLCMATNAAG 3790
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/270 (22%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C G+P P ++W + + Y++T +L KN A A +
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL-----FIKNA---APKDAGIYG 680
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +++ +APK + + + + K + P P + W++ D
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ S+ + + + L IQ + LD ++ CVA N+ G++ L + P
Sbjct: 741 ELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP----- 792
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYK-DGEEL--KPGDIHRIISGQDGTC 349
P F++ + + G+ V L C V G P+P +KW + D + +P + I + G
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
+ GTY CEA N G S ++
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTV 882
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 4068
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 4069 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 4110
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 4167 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 4221
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 4222 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 3694
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 3695 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 3750
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 3751 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3808
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 3809 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 3844
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 1157 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 1255
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 1256 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 1307
Score = 48.8 bits (111), Expect = 3e-04
Identities = 79/304 (25%), Positives = 116/304 (38%), Gaps = 58/304 (19%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ M +L G ++ ECK G P P + WFK EL+P + ++
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 148 TNSL--GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
T L G Y C+A N G+A+ L V P F+ V
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDV------------------GSPPVFIQEPADVS 803
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYR-DDQPVDES--SRCHLGKEERGVFFLDIQALEFLD 262
+I V PEP++ W R D+ P+ S + + G F I L D
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF--ILNLWASD 861
Query: 263 QAEWKCVAFNDFG--QSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVI-G 318
+ + C A N FG QS T+ + L+ P P A + + + L C ++ G
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV-----ANVIEGQQLTLPCTLLAG 916
Query: 319 VPQPVLKWYKDGEEL---------KPGDIH-RIISGQDGTCSLGTYTCEASNCMGVAASS 368
P P +W K+ L G +H + QDG G YTC ASN G +
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG----GEYTCVASNVAGTNNKT 972
Query: 369 ASLL 372
S++
Sbjct: 973 TSVV 976
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 4149 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 4195
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 4196 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 4245
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 4246 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 4301 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 4335
Score = 46.4 bits (105), Expect = 0.002
Identities = 68/283 (24%), Positives = 104/283 (36%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 4239
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 4240 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 4281
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 4282 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 4336
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
F+ + P +K + N L +N C+V G P P ++W + G +++
Sbjct: 4337 VKAIGFVYVKEPPVFKGD-YPSNWIEPLGGNAILN--CEVKGDPTPTIQWNRKGVDIEIS 4393
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 4394 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 4377 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4432
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 4433 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4488
Query: 342 IS 343
+S
Sbjct: 4489 LS 4490
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 3793 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3834
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 3891
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 3892 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 3947
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 3948 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 3982
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 4365 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 4423
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 4424 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 4474
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 4475 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 4516
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 4444 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 4503
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 4504 TSEFECVARNLMG 4516
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 91.1 bits (216), Expect = 6e-17
Identities = 77/285 (27%), Positives = 125/285 (43%), Gaps = 38/285 (13%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG--TNSLGS 153
+ ++T +S EC+V G P P ++W KDG L G + QL + G
Sbjct: 2302 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGR 2361
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A N G +L+V + + +++P+ + SV K
Sbjct: 2362 YVCVAVNVAGMTDKKYDLSVHAPPS---------IIGNHRSPENI----SVVEK--NSVS 2406
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T + + P PS W++D PV S+ + R L + D ++ CV N
Sbjct: 2407 LTCEASGIPLPSTTWFKDGWPVSLSNSVRILSGGR---MLRLMQTTMEDAGQYTCVVRNA 2463
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G+ L +++P H LE+++ + ++ +V L C+V G P P + W+KDG+ L
Sbjct: 2464 AGEERKIFGLSVLVPPHIVGENTLEDVK--VKEKQSVTLTCEVTGNPVPEITWHKDGQPL 2521
Query: 334 KPGDIHRIISG----QDGTCSL---GTYTCEASNCMGVAASSASL 371
+ + H IISG Q + G YTC AS+ G + S SL
Sbjct: 2522 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2566
Score = 82.2 bits (194), Expect = 3e-14
Identities = 76/279 (27%), Positives = 113/279 (40%), Gaps = 26/279 (9%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD L +T N G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGST--SMTFLNR-G 1973
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1974 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 2029
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEE-RGVFFLDIQALEFLDQAEWKCVAF 271
R + P PSL W +D PV S G + G L + + + D + CVA
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPVSSFSN---GLQVLSGGRILALTSTQISDTGRYTCVAV 2086
Query: 272 NDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE 331
N G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 2087 NAAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGH 2142
Query: 332 EL--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 2143 PLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 81.0 bits (191), Expect = 6e-14
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 1450 VPPTIIGTNFPKEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 1507
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 1508 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 1562
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ K P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 1563 SLIKLECKTRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 1618
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LEC G P P+L W
Sbjct: 1619 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECNAAGNPSPILTWL 1676
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 1677 KDGVPVKANDNFRIEAG 1693
Score = 79.0 bits (186), Expect = 2e-13
Identities = 83/306 (27%), Positives = 129/306 (42%), Gaps = 43/306 (14%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK- 138
S K N + VP + P+ ENL V+ +S C+V GFP P LSW K+ Q +K
Sbjct: 2952 SAKKYFNLNVHVPPSVIGPK-SENLTVVVNN--FISLTCEVSGFPPPDLSWLKNXQPIKL 3008
Query: 139 -------PGD-VYQL--TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQL 188
PG Q+ + G Y CIA N G++ LTV + + + + L
Sbjct: 3009 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVY-VPPSIKDHDSESL 3067
Query: 189 FSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
N V SV + + A+PP P + WY++ + + ES+ + + +
Sbjct: 3068 SVVN-----VREGTSVSLECESN-------AVPP-PVITWYKNGRMITESTHVEILADGQ 3114
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG 308
L I+ E D ++ C A N G+ + L + +P + P E + +
Sbjct: 3115 ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISN 3168
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISG-------QDGTCSLGTYTCEAS 359
V L C G+P P + W K+ + ++ D RI+SG + G YTC AS
Sbjct: 3169 PVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIAS 3228
Query: 360 NCMGVA 365
N G A
Sbjct: 3229 NMEGKA 3234
Score = 78.6 bits (185), Expect = 3e-13
Identities = 66/271 (24%), Positives = 111/271 (40%), Gaps = 29/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT-----------NSLGSYCCIAKNCM 162
++ EC+ P+ LSW+KDGQ LK D + + G Y C+A N
Sbjct: 2693 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2752
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G+ ++ ++ + +KL N +G ++ + I+ P + P
Sbjct: 2753 GEDELDFDVNIQVPPSF----QKLWEIG-NMLDTGRNG-EAKDVIINNPISLYCETNAAP 2806
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P+L WY+D P+ S + + R L I + D + CVA N+ G+
Sbjct: 2807 PPTLTWYKDGHPLTSSDKVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYD 2863
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+++++P + L +L ++ A+ +EC G P P W KDG+ L D H+
Sbjct: 2864 VRVLVPPIIEGANSDLPEEVTVLVNKSAL-IECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2922
Query: 342 ISG-------QDGTCSLGTYTCEASNCMGVA 365
+S +G Y C A N G A
Sbjct: 2923 LSNGRILQILNTQITDIGRYVCVAENTAGSA 2953
Score = 77.0 bits (181), Expect = 1e-12
Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS EC+ P PV++W+K+G+ + ++ G I K
Sbjct: 3065 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 3120
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 3121 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 3176
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 3177 TGIPPPTIAWLKNYKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3235
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 3236 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 3293
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 3294 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3327
Score = 72.9 bits (171), Expect = 2e-11
Identities = 66/262 (25%), Positives = 104/262 (39%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ ECK G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 1564 LIKLECKTRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 1617
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I A P P L W
Sbjct: 1618 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECNAAGNPSPILTW 1675
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 1676 LKDGVPVKANDNFRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 1732
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 1733 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAG 1812
Score = 72.9 bits (171), Expect = 2e-11
Identities = 70/278 (25%), Positives = 111/278 (39%), Gaps = 42/278 (15%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG-------TN----SLGSYCCIA 158
E+ V+ C+V G P P ++W KDGQ L+ + + + TN G Y C+A
Sbjct: 2494 EKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA 2553
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ G S S L V + + P+ V ++ P +
Sbjct: 2554 SSPAGHKSRSFSLNVF-------VSPTIAGVGSDGNPE------DVTVILNSPTSLVCEA 2600
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA-EWKCVAFNDFGQS 277
P ++ W++D P++ + + R + L+ Q D A + CVA N+ G+
Sbjct: 2601 YSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQE----DNAGRYSCVATNEAGEM 2656
Query: 278 VTSCFLKLIIPRHYKKPRF----LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ +K+ IP K L + + + LEC+ +P L WYKDG+ L
Sbjct: 2657 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2716
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
K D H I+ T + G YTC ASN G
Sbjct: 2717 KSDD-HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2753
Score = 72.5 bits (170), Expect = 2e-11
Identities = 76/283 (26%), Positives = 114/283 (40%), Gaps = 46/283 (16%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD---------VYQLTGTN--S 150
E + ++ + L+ EC G P P SW KDGQ L D + Q+ T
Sbjct: 2881 EEVTVLVNKSALI--ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITD 2938
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKI 208
+G Y C+A+N G A L V P V G KS + +
Sbjct: 2939 IGRYVCVAENTAGSAKKYFNLNVH-------------------VPPSVIGPKSENLTVVV 2979
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+ T +V+ P P L W ++ QP+ ++ + R L I + D E+ C
Sbjct: 2980 NNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRT---LQIIRAKVSDGGEYTC 3036
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
+A N G+S L + +P K E+L + EG +V+LEC+ VP PV+ WY
Sbjct: 3037 IAINXAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVSLECESNAVPPPVITWY 3095
Query: 328 KDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
K+G + + + + GQ G Y C A N G
Sbjct: 3096 KNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3138
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 3455 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3514
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 3515 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 3558
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 3559 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 3614
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 3615 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 3672
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 3673 SGGRYLQINNADLGDTANYTCVASNIAG 3700
Score = 70.5 bits (165), Expect = 9e-11
Identities = 71/270 (26%), Positives = 106/270 (39%), Gaps = 43/270 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLTGT--NSLGSYCCIAKNC 161
V+ +C G P P ++W KD Q + G V Q+ T G Y C+A N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNA 1903
Query: 162 MGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP 221
G+ T + IQ ++E L+ K + + + P + K A
Sbjct: 1904 AGE-------TQQHIQLHVHEPPSLEDAGK---------MLNETVLVSNPVQLECKAAGN 1947
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P + WY+D+ + S+ RG +DI++ + D +KCVA N G T
Sbjct: 1948 PVPVITWYKDNCLLSGSTSMTF--LNRGQI-IDIESAQISDAGIYKCVAINSAG--ATEL 2002
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHR 340
F L + H N + V LEC+ G+P P L W KDG + + +
Sbjct: 2003 FYSLQV--HVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQ 2060
Query: 341 IISG-------QDGTCSLGTYTCEASNCMG 363
++SG G YTC A N G
Sbjct: 2061 VLSGGRILALTSTQISDTGRYTCVAVNAAG 2090
Score = 70.1 bits (164), Expect = 1e-10
Identities = 64/294 (21%), Positives = 112/294 (38%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 1351 YNLKVHVPPVIKDKEQVSNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 1408
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL--- 201
+ G+ S A Q N + + P + G
Sbjct: 1409 TVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 1460
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
K V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 1461 KEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 1518
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LECK G+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECKTRGLPM 1576
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 1577 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 69.7 bits (163), Expect = 2e-10
Identities = 70/275 (25%), Positives = 109/275 (39%), Gaps = 39/275 (14%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPG-DVYQLTGTNSL----------GSYCCIAKNCMG 163
S C+ +P ++WFKDG L+ ++ L G +L G Y C+A N G
Sbjct: 2595 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2654
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ E+ V I +N+ + L+ +PK V+ K++ + P
Sbjct: 2655 EMIKHYEVKVY-IPPIINKGD---LWGPGLSPK------EVKIKVNNTLTLECEAYAIPS 2704
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
SL WY+D QP+ H+ G L I+ + D + CVA N G+ +
Sbjct: 2705 ASLSWYKDGQPLKSDD--HVNIAANG-HTLQIKEAQISDTGRYTCVASNIAGEDELDFDV 2761
Query: 284 KLIIPRHYKKPRFLENL-----QAILSD---EGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ +P ++K + N+ D ++L C+ P P L WYKDG L
Sbjct: 2762 NIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2821
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMG 363
D I+ G + G YTC A N G
Sbjct: 2822 SDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2856
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 3908 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 3967
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 3968 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 4009
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 4010 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 4066
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 4067 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 4122
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 4123 SIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4164
Score = 68.1 bits (159), Expect = 5e-10
Identities = 82/289 (28%), Positives = 116/289 (40%), Gaps = 51/289 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 1745 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYR 1804
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 1805 CMAANTAGDHKKEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 1848
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 1849 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDG- 330
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 1906 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNC 1959
Query: 331 --------EELKPGDIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
L G I I S Q G Y C A N G SL
Sbjct: 1960 LLSGSTSMTFLNRGQIIDIESAQ--ISDAGIYKCVAINSAGATELFYSL 2006
Score = 67.3 bits (157), Expect = 8e-10
Identities = 76/291 (26%), Positives = 118/291 (40%), Gaps = 46/291 (15%)
Query: 103 NLQAVLTEEGLVSFECKVVGFPTPVLSWFKDG----------QELKPGDVYQLTGT--NS 150
N+ AV+ V EC+ G P P L+W KDG Q L G + LT T +
Sbjct: 2019 NMVAVVVNNP-VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSTQISD 2077
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y C+A N G+ +L V N + EE+ + + ++VE
Sbjct: 2078 TGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLIS----------QAVELLCQS 2127
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
AIPP P+L W +D P+ + + E R V L I+ + D + C A
Sbjct: 2128 D-------AIPP-PTLTWLKDGHPLLKKPGLSIS-ENRSV--LKIEDAQVQDTGRYTCEA 2176
Query: 271 FNDFGQSVTSCF-LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKD 329
N G++ + + + +P + L L I + ++L C+ G+P P L W K
Sbjct: 2177 TNVAGKTEKKNYNVNIWVPPNIGGSDELTQLTVI--EGNLISLLCESSGIPPPNLIWKKK 2234
Query: 330 GEEL---KPGDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
G + G + + G+ S+ Y+C ASN G A +L
Sbjct: 2235 GSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL 2285
Score = 65.7 bits (153), Expect = 2e-09
Identities = 64/264 (24%), Positives = 104/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 3170 VTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 3225
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 3226 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 3283
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 3284 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 3342
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L + + ++N+EC+ G P P + W K+G L G + R
Sbjct: 3343 IRGNKDEAEKLMTYV--DTSINIECRXTGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 3400
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 3401 IVRAQ--VSDVAVYTCVASNRAGV 3422
Score = 62.5 bits (145), Expect = 2e-08
Identities = 71/289 (24%), Positives = 113/289 (39%), Gaps = 28/289 (9%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P Q + T EG+ V+ CK G P P + W K G+ + G + GS
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD--GSLYV 1038
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL---KSVEAKI--DEP 211
++ G+ S T + + +L ++ + + + GL K VE + E
Sbjct: 1039 VSPE--GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDLRGLSQDKPVEISVLAGEE 1096
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
+V P P + W ++ Q + S H + I D + CVA
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVAT 1153
Query: 272 NDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE 331
N G + L + +P K R ++L+ + V++ C G P PV+ W K G
Sbjct: 1154 NIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVITWSKGGS 1209
Query: 332 E-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 1210 TMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Score = 62.1 bits (144), Expect = 3e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 1248 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 1294
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 1295 KPTIKWLHNGRELT-GREPGISILEEGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 1352
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 1353 LKVHVPPVIKDKEQVSNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 62.1 bits (144), Expect = 3e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 3244 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 3300
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 3301 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 3355
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 3356 YVDTSINIECRXTGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 3412
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 3413 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 3470
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 3471 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3514
Score = 59.3 bits (137), Expect = 2e-07
Identities = 68/271 (25%), Positives = 104/271 (38%), Gaps = 28/271 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
+S C+ P P L+W+KDG L D V L G G I + + A +
Sbjct: 2796 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPG----GRVLQIPRAKVEDAGRYTCVA 2851
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS-----VEAKIDEPFRFTIKVAIPPEPSLL 227
V + E+ LQ + P + G S V +++ + P P
Sbjct: 2852 VNEAG-----EDSLQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS 2906
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W +D QP+ E R L I + D + CVA N G + L + +
Sbjct: 2907 WQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2963
Query: 288 PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG--- 344
P P+ ENL ++++ ++L C+V G P P L W K+ + +K I+ G
Sbjct: 2964 PPSVIGPKS-ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRT 3020
Query: 345 ----QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A N G + SL
Sbjct: 3021 LQIIRAKVSDGGEYTCIAINXAGESKKKFSL 3051
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 3551 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 3610
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 3611 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 3664
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 3665 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 3721
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 3722 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 3775
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 3776 VTDTGRYLCMATNAAG 3791
Score = 56.8 bits (131), Expect = 1e-06
Identities = 61/270 (22%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C G+P P ++W + + Y++T +L KN A A +
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTL-----FIKNA---APKDAGIYG 680
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
N +++ +APK + + + + K + P P + W++ D
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ S+ + + + L IQ + LD ++ CVA N+ G++ L + P
Sbjct: 741 ELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP----- 792
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYK-DGEEL--KPGDIHRIISGQDGTC 349
P F++ + + G+ V L C V G P+P +KW + D + +P + I + G
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 350 SL--------GTYTCEASNCMGVAASSASL 371
+ GTY CEA N G S ++
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTV 882
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 4010 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 4069
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 4070 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 4111
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 4112 TWHKDGRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4167
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 4168 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 4222
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 4223 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4255
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 3640 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 3695
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 3696 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 3751
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 3752 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 3809
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 3810 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 3845
Score = 50.4 bits (115), Expect = 1e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 1097 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIA 1156
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 1157 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 1198
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 1199 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 1255
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 1256 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 1307
Score = 48.8 bits (111), Expect = 3e-04
Identities = 79/304 (25%), Positives = 116/304 (38%), Gaps = 58/304 (19%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ M +L G ++ ECK G P P + WFK EL+P + ++
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 148 TNSL--GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
T L G Y C+A N G+A+ L V P F+ V
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDV------------------GSPPVFIQEPADVS 803
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYR-DDQPVDES--SRCHLGKEERGVFFLDIQALEFLD 262
+I V PEP++ W R D+ P+ S + + G F I L D
Sbjct: 804 MEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF--ILNLWASD 861
Query: 263 QAEWKCVAFNDFG--QSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVI-G 318
+ + C A N FG QS T+ + L+ P P A + + + L C ++ G
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV-----ANVIEGQQLTLPCTLLAG 916
Query: 319 VPQPVLKWYKDGEEL---------KPGDIH-RIISGQDGTCSLGTYTCEASNCMGVAASS 368
P P +W K+ L G +H + QDG G YTC ASN G +
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG----GEYTCVASNVAGTNNKT 972
Query: 369 ASLL 372
S++
Sbjct: 973 TSVV 976
Score = 47.6 bits (108), Expect = 7e-04
Identities = 68/283 (24%), Positives = 105/283 (37%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 4181 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 4240
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 4241 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 4282
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 4283 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 4337
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
+ F+ + P +K + N L +N C+V G P P ++W + G +++
Sbjct: 4338 VKATGFVYVKEPPVFKGD-YPSNWIEPLGGNAILN--CEVKGDPTPTIQWNRKGVDIEIS 4394
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 4395 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4435
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 4090 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4149
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 4150 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 4196
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 4197 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 4246
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 4247 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4301
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 4302 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 4336
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 4378 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 4433
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 4434 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 4489
Query: 342 IS 343
+S
Sbjct: 4490 LS 4491
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 3734 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3793
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 3794 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 3835
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 3836 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 3892
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 3893 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 3948
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 3949 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 3983
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 4366 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 4424
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 4425 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 4475
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 4476 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 4517
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 4445 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 4504
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 4505 TSEFECVARNLMG 4517
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16
to 1881) protein.
Length = 1897
Score = 89.0 bits (211), Expect = 2e-16
Identities = 69/269 (25%), Positives = 117/269 (43%), Gaps = 12/269 (4%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 38 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 97
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 98 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 157
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W++D PVD ++ K+ R L I++ E DQ +++CVA N G S L +
Sbjct: 158 WFKDFLPVDPATSNGRIKQLRSGA-LQIESSEESDQGKYECVATNSAGTRY-SAPANLYV 215
Query: 288 PRHYKKPRFL--ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD---IHRII 342
PRF + Q ++ G+VNL C +G P P +KW EEL D + R +
Sbjct: 216 RVRRVAPRFSIPPSSQEVMPG-GSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNV 274
Query: 343 SGQDGTCSLGTYTCEASNCMGVAASSASL 371
YTC A + +G+ ++A +
Sbjct: 275 LELSNVVRSANYTCVAISSLGMIEATAQV 303
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 89.0 bits (211), Expect = 2e-16
Identities = 69/269 (25%), Positives = 117/269 (43%), Gaps = 12/269 (4%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 48 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 107
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 108 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 167
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W++D PVD ++ K+ R L I++ E DQ +++CVA N G S L +
Sbjct: 168 WFKDFLPVDPATSNGRIKQLRSGA-LQIESSEESDQGKYECVATNSAGTRY-SAPANLYV 225
Query: 288 PRHYKKPRFL--ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD---IHRII 342
PRF + Q ++ G+VNL C +G P P +KW EEL D + R +
Sbjct: 226 RVRRVAPRFSIPPSSQEVMPG-GSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNV 284
Query: 343 SGQDGTCSLGTYTCEASNCMGVAASSASL 371
YTC A + +G+ ++A +
Sbjct: 285 LELSNVVRSANYTCVAISSLGMIEATAQV 313
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 89.0 bits (211), Expect = 2e-16
Identities = 69/269 (25%), Positives = 117/269 (43%), Gaps = 12/269 (4%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 48 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 107
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 108 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 167
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W++D PVD ++ K+ R L I++ E DQ +++CVA N G S L +
Sbjct: 168 WFKDFLPVDPATSNGRIKQLRSGA-LQIESSEESDQGKYECVATNSAGTRY-SAPANLYV 225
Query: 288 PRHYKKPRFL--ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD---IHRII 342
PRF + Q ++ G+VNL C +G P P +KW EEL D + R +
Sbjct: 226 RVRRVAPRFSIPPSSQEVMPG-GSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNV 284
Query: 343 SGQDGTCSLGTYTCEASNCMGVAASSASL 371
YTC A + +G+ ++A +
Sbjct: 285 LELSNVVRSANYTCVAISSLGMIEATAQV 313
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 89.0 bits (211), Expect = 2e-16
Identities = 69/269 (25%), Positives = 117/269 (43%), Gaps = 12/269 (4%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 48 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 107
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 108 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 167
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W++D PVD ++ K+ R L I++ E DQ +++CVA N G S L +
Sbjct: 168 WFKDFLPVDPATSNGRIKQLRSGA-LQIESSEESDQGKYECVATNSAGTRY-SAPANLYV 225
Query: 288 PRHYKKPRFL--ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD---IHRII 342
PRF + Q ++ G+VNL C +G P P +KW EEL D + R +
Sbjct: 226 RVRRVAPRFSIPPSSQEVMPG-GSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNV 284
Query: 343 SGQDGTCSLGTYTCEASNCMGVAASSASL 371
YTC A + +G+ ++A +
Sbjct: 285 LELSNVVRSANYTCVAISSLGMIEATAQV 313
>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
Length = 1918
Score = 89.0 bits (211), Expect = 2e-16
Identities = 69/269 (25%), Positives = 117/269 (43%), Gaps = 12/269 (4%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 68 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 127
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 128 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 187
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
W++D PVD ++ K+ R L I++ E DQ +++CVA N G S L +
Sbjct: 188 WFKDFLPVDPATSNGRIKQLRSGA-LQIESSEESDQGKYECVATNSAGTRY-SAPANLYV 245
Query: 288 PRHYKKPRFL--ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD---IHRII 342
PRF + Q ++ G+VNL C +G P P +KW EEL D + R +
Sbjct: 246 RVRRVAPRFSIPPSSQEVMPG-GSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNV 304
Query: 343 SGQDGTCSLGTYTCEASNCMGVAASSASL 371
YTC A + +G+ ++A +
Sbjct: 305 LELSNVVRSANYTCVAISSLGMIEATAQV 333
>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
phosphatase, receptor type, S protein.
Length = 1501
Score = 88.2 bits (209), Expect = 4e-16
Identities = 72/283 (25%), Positives = 123/283 (43%), Gaps = 11/283 (3%)
Query: 98 PRFM-ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
PRF+ E + G+ SF C+ G P P ++W K G+++ + S G+
Sbjct: 33 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK-FVHGLKSVEAKIDEPFRFT 215
I + + E ++ ++ KL + ++Q P F + + K+ E R
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152
Query: 216 IKVAIP---PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
+ P+P + W++D PVD S+ K+ R L I++ E DQ +++CVA N
Sbjct: 153 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGA-LQIESSEETDQGKYECVATN 211
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE 331
G +S L + PRF + + + G VN+ C +G P P +KW + E
Sbjct: 212 SAGVRYSSP-ANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAE 270
Query: 332 ELKPGD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
+L P D + R + YTC A + +GV + A +
Sbjct: 271 DLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQI 313
Score = 43.6 bits (98), Expect = 0.011
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 7/72 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W + ++L P D V +LT +Y C+A + +G
Sbjct: 247 GNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV 306
Query: 165 ASSSAELTVEDI 176
+ A++TV+ +
Sbjct: 307 IEAVAQITVKSL 318
Score = 42.7 bits (96), Expect = 0.020
Identities = 46/195 (23%), Positives = 74/195 (37%), Gaps = 17/195 (8%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+F+ K F + P+P + W + + V+ + +E
Sbjct: 31 EPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 90
Query: 253 LDIQALEF-LDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQA-----ILSD 306
L IQ L D+ ++CVA N G+ KL + R + P N+ ++
Sbjct: 91 LRIQPLRTPRDENVYECVAQNSVGEITVHA--KLTVLREDQLPSGFPNIDMGPQLKVVER 148
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKP----GDIHRIISG-----QDGTCSLGTYTCE 357
+ C G P P + W+KD + P G I ++ SG G Y C
Sbjct: 149 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECV 208
Query: 358 ASNCMGVAASSASLL 372
A+N GV SS + L
Sbjct: 209 ATNSAGVRYSSPANL 223
>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
phosphatase, receptor type, sigma isoform 3 precursor
variant protein.
Length = 1560
Score = 88.2 bits (209), Expect = 4e-16
Identities = 72/283 (25%), Positives = 123/283 (43%), Gaps = 11/283 (3%)
Query: 98 PRFM-ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
PRF+ E + G+ SF C+ G P P ++W K G+++ + S G+
Sbjct: 59 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 118
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK-FVHGLKSVEAKIDEPFRFT 215
I + + E ++ ++ KL + ++Q P F + + K+ E R
Sbjct: 119 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 178
Query: 216 IKVAIP---PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
+ P+P + W++D PVD S+ K+ R L I++ E DQ +++CVA N
Sbjct: 179 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGA-LQIESSEETDQGKYECVATN 237
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE 331
G +S L + PRF + + + G VN+ C +G P P +KW + E
Sbjct: 238 SAGVRYSSP-ANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAE 296
Query: 332 ELKPGD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
+L P D + R + YTC A + +GV + A +
Sbjct: 297 DLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQI 339
Score = 43.6 bits (98), Expect = 0.011
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 7/72 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W + ++L P D V +LT +Y C+A + +G
Sbjct: 273 GNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV 332
Query: 165 ASSSAELTVEDI 176
+ A++TV+ +
Sbjct: 333 IEAVAQITVKSL 344
Score = 42.7 bits (96), Expect = 0.020
Identities = 46/195 (23%), Positives = 74/195 (37%), Gaps = 17/195 (8%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+F+ K F + P+P + W + + V+ + +E
Sbjct: 57 EPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 116
Query: 253 LDIQALEF-LDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQA-----ILSD 306
L IQ L D+ ++CVA N G+ KL + R + P N+ ++
Sbjct: 117 LRIQPLRTPRDENVYECVAQNSVGEITVHA--KLTVLREDQLPSGFPNIDMGPQLKVVER 174
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKP----GDIHRIISG-----QDGTCSLGTYTCE 357
+ C G P P + W+KD + P G I ++ SG G Y C
Sbjct: 175 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECV 234
Query: 358 ASNCMGVAASSASLL 372
A+N GV SS + L
Sbjct: 235 ATNSAGVRYSSPANL 249
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 85.4 bits (202), Expect = 3e-15
Identities = 74/277 (26%), Positives = 130/277 (46%), Gaps = 36/277 (12%)
Query: 104 LQAVLTEEGLVSFECKVVGFPTPV-LSWFKDGQELKPGDVYQLTGTNSL----------- 151
+ AV E G V + CK+ + ++W+ ++L+ + Y++T + +
Sbjct: 25078 MHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 25137
Query: 152 --GSYCCIAKNCMGQASSSAELTVEDIQNQLN-----EEEKLQLFSKN-----QAPKFVH 199
G+Y C N G+ SS AEL V+ ++ + +K++ + + P+F
Sbjct: 25138 DDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTL 25197
Query: 200 GLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD--ESSRCHLGKEERGVFFLDIQA 257
L + A + E RF + + + PEP + WY+ Q + ++ + + + ++G++ L I +
Sbjct: 25198 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 25257
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK------KPRFLENLQAILSDEG-AV 310
+ D AE+ VA N +G+ SC KL + H +P F L EG +V
Sbjct: 25258 VTTDDDAEYTVVARNKYGED--SCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSV 25315
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQD 346
E +V G+P P LKW KDG+ L G +I I G D
Sbjct: 25316 CFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD 25352
Score = 77.4 bits (182), Expect = 8e-13
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVF 251
QAP F L+SV F ++ P P + W+RD Q + S+ + G
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-V 310
L I A+ + + A N GQ+ ++ +L++ P F++ LQ++ +G+ V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTA--ELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 311 NLECKVIGVPQPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNC 361
L+ +V G+P PV+K+Y+DG E+ + GD++ ++ + GTY+ A+N
Sbjct: 122 RLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 362 MGVAASSASLL 372
+G A S+A LL
Sbjct: 182 VGRATSTAELL 192
Score = 69.7 bits (163), Expect = 2e-10
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 22/198 (11%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+ + L+ V + +P RF ++ P+P + WY+++Q + +C + +
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK--------KPRFLENLQAIL 304
L I+A D A + C A ND+G + TS L + +P P + LQ +
Sbjct: 3251 LLIEAFP-EDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3309
Query: 305 SDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GT 353
+ EG +C+V G V WY +++KP R+ +D T L GT
Sbjct: 3310 TSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGT 3367
Query: 354 YTCEASNCMGVAASSASL 371
YT A+N +G +S+A+L
Sbjct: 3368 YTFVANNAVGQVSSTANL 3385
Score = 65.7 bits (153), Expect = 2e-09
Identities = 54/177 (30%), Positives = 79/177 (44%), Gaps = 7/177 (3%)
Query: 179 QLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF--RFTIKVAIPPEPSLLWYRDDQPVD 236
+L E ++ QL + P FV LK V K E RF +KV P P W+ D Q +
Sbjct: 1396 RLEETDESQL-ERLYKPVFV--LKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIV 1452
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
+ +E G L I D EW VA N G+S S L + H KP F
Sbjct: 1453 NDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMF 1512
Query: 297 LENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL 351
+E L+ + EG+ + ++ + G P P + W K+ + + P +I I G G +L
Sbjct: 1513 VEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL 1569
Score = 62.5 bits (145), Expect = 2e-08
Identities = 60/249 (24%), Positives = 106/249 (42%), Gaps = 13/249 (5%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYC 155
P+ E +Q+ +G F +VVG P P W+K+G +++ D +Y +++
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE-- 2089
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
+ ++ + S+S + +I + + L L Q F L+ V AK +
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLITFTQELQDVVAKEKDTMATF 2148
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
P + WY+D V E + + +R V FL I ++ D ++ CV D
Sbjct: 2149 ECETSEPFVKVKWYKDGMEVHEGDKYRM-HSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2207
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELK 334
T+ KLI+ + F++ LQ I + + + LEC ++ KWY + ELK
Sbjct: 2208 VKTTA---KLIVEGAVVE--FVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELK 2261
Query: 335 PGDIHRIIS 343
+ I S
Sbjct: 2262 SNGKYTITS 2270
Score = 60.9 bits (141), Expect = 7e-08
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 2/187 (1%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + LQ+V+ EG +FE + GFP P +SWF+DGQ + + + + S G
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
S L + Q +L + ++ P FV L+S+ + R +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+V P P + +YRD + S + +E ++ L I D + A N G+
Sbjct: 126 RVTGIPNPVVKFYRDGAEIQSSLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 277 SVTSCFL 283
+ ++ L
Sbjct: 185 ATSTAEL 191
Score = 59.7 bits (138), Expect = 2e-07
Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 33/238 (13%)
Query: 79 KSIKMIHNSHPTVPKNYRKPRF---MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQ 135
+++K I T+ R P F + N A + E V F + P P ++W+K GQ
Sbjct: 25174 RTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGEN--VRFGVTITVHPEPHVTWYKSGQ 25231
Query: 136 ELKPGD------------VYQLT----GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQ 179
++KPGD +YQLT T+ Y +A+N G+ S A+LTV
Sbjct: 25232 KIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----T 25286
Query: 180 LNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS 239
L+ P F L + E + + F I+V+ P P+L W +D QP+
Sbjct: 25287 LHPPPT----DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGP 25342
Query: 240 RCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR-HYKKPRF 296
+ E + L I+ D ++ A N G TSC L + R YKK F
Sbjct: 25343 NIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGS--TSCQAHLQVERLRYKKQEF 25398
Score = 59.3 bits (137), Expect = 2e-07
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 6/162 (3%)
Query: 184 EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
+K++L +APK ++S F ++V P+P WY++ ++ S R +
Sbjct: 2021 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2080
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI 303
E V L I+ + D A A N G++ + FL + + + F + LQ +
Sbjct: 2081 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL---LVQAKQLITFTQELQDV 2137
Query: 304 LSDE--GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
++ E EC+ P +KWYKDG E+ GD +R+ S
Sbjct: 2138 VAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHS 2178
Score = 58.4 bits (135), Expect = 4e-07
Identities = 70/255 (27%), Positives = 114/255 (44%), Gaps = 31/255 (12%)
Query: 100 FMENLQAVLTEEG--LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
F + LQ V+ +E + +FEC+ P + W+KDG E+ GD Y++ + + I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKV-HFLSI 2187
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
A + + VED N + +L + +FV L+ +E + E + ++
Sbjct: 2188 LTIDTSDAEDYSCVLVEDE----NVKTTAKLIVEGAVVEFVKELQDIE--VPESYSGELE 2241
Query: 218 VAIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+ PE WY +D + + + + RG L ++ + DQ E+ V
Sbjct: 2242 CIVSPENIEGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFV----IDG 2296
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSD----EG-AVNLECKVIGVPQPVLKWYKDGE 331
T+C LK+ KPR + LQ LSD EG V LE KV + W KDG+
Sbjct: 2297 KKTTCKLKM-------KPRPIAILQG-LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQ 2347
Query: 332 ELKPGD-IHRIISGQ 345
E++P D +H +I Q
Sbjct: 2348 EVQPSDRVHIVIDKQ 2362
Score = 55.6 bits (128), Expect = 3e-06
Identities = 48/181 (26%), Positives = 76/181 (41%), Gaps = 28/181 (15%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL----------GSYCCIAKNC 161
F+ KVVG P P WF DGQ++ +++ GT SL G + +A+N
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 162 MGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP 221
G++S S LTVE +++Q+ P FV LK+V K ++
Sbjct: 1490 AGRSSISVILTVEAVEHQVK-------------PMFVEKLKNVNIKEGSRLEMKVRATGN 1536
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKE-ERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTS 280
P P ++W ++ + + E +G L I + D A + A N G+ T
Sbjct: 1537 PNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTR 1596
Query: 281 C 281
C
Sbjct: 1597 C 1597
Score = 55.2 bits (127), Expect = 4e-06
Identities = 83/303 (27%), Positives = 118/303 (38%), Gaps = 55/303 (18%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ---------------LTGTNSLG 152
L E G V F C+V G P P + W K G L G Y+ +T + G
Sbjct: 1047 LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1106
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN------------QAPKFVHG 200
Y + +N G+ S+SA L E L + ++ L+ AP FV+
Sbjct: 1107 EYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPEVGETAPGFVYS 1166
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS-RCHLGKE-ERGVFFLDIQAL 258
E + ++ K + Y +DQ SS L KE E + ++ L
Sbjct: 1167 --EYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEEL 1224
Query: 259 EFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIG 318
D E V ++ ++V S F I K R LE + V CK+ G
Sbjct: 1225 LEEDGEEKMAVDISE-SEAVESGFDLRI-----KNYRILEGM--------GVTFHCKMSG 1270
Query: 319 VPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASS 368
P P + WYKDG+ +K G+ +++ QDG SL G YT ASN G A S
Sbjct: 1271 YPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICS 1330
Query: 369 ASL 371
L
Sbjct: 1331 GKL 1333
Score = 55.2 bits (127), Expect = 4e-06
Identities = 58/251 (23%), Positives = 108/251 (43%), Gaps = 21/251 (8%)
Query: 98 PRFMENLQAVLTEEGLVSFECKVV-GFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ ++ LQ V + G + C ++ G P P +SW+K+ Q L G Y L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 148 TNSLGS----YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+ Y C AKN G A++SA L+VE + ++ ++++ ++ P + L+
Sbjct: 3253 IEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVY----PPAIITPLQD 3307
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+P RF +V+ + + WY D+ + + SR + + L+I D+
Sbjct: 3308 TVTSEGQPARFQCRVS-GTDLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDE 3365
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPV 323
+ VA N GQ ++ L L P R + ++ + + + L + G+
Sbjct: 3366 GTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAE 3425
Query: 324 LKWYKDGEELK 334
L+ K E L+
Sbjct: 3426 LQLSKINETLE 3436
Score = 52.4 bits (120), Expect = 2e-05
Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 3/124 (2%)
Query: 162 MGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP 221
+ + S + T E + E + + S P V GL+ D +F +K
Sbjct: 26324 ISETKKSDQKTTESTVTRKTEPKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGE 26381
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P+ +W +D + + + + L E++G FFL+I + D + C N G +SC
Sbjct: 26382 PRPTAIWTKDGKAITQGGKYKL-SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSC 26440
Query: 282 FLKL 285
L +
Sbjct: 26441 KLTI 26444
Score = 52.0 bits (119), Expect = 3e-05
Identities = 47/211 (22%), Positives = 95/211 (45%), Gaps = 36/211 (17%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS--RCHLGKEERGVFF 252
P F+ + + + + + ++ V P+P + W+ + + S+ + ++ +
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL--------------IIPRHYKK----- 293
L LE D+ E+ C+A ND+G+++ S +LK+ + + +K
Sbjct: 3517 L-FTKLE--DEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC 3573
Query: 294 -PRFLENLQAILSDEGAVNL-ECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL 351
P FL+ L+ I +G + E V+G P P + W+K+ ++L + II +G+ +
Sbjct: 3574 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 3633
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G Y C+A N +G + +A LL
Sbjct: 3634 IVNDPQREDSGLYICKAENMLGESTCAAELL 3664
Score = 51.2 bits (117), Expect = 6e-05
Identities = 36/146 (24%), Positives = 65/146 (44%), Gaps = 17/146 (11%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C A N G+ ++SA+LTV K AP ++ +E +
Sbjct: 4310 GEYVCEALNDSGKTATSAKLTVV----------------KRAAPVIKRKIEPLEVALGHL 4353
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
+FT ++ P W++ + + ES +C + + + + L+I + +D E+ C A
Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 4412
Query: 272 NDFGQSVTSCFLKLIIPRHYKKPRFL 297
N++G + L + +P KK R L
Sbjct: 4413 NEYGSVSCTATLTVTVPGGEKKVRKL 4438
Score = 50.0 bits (114), Expect = 1e-04
Identities = 37/149 (24%), Positives = 68/149 (45%), Gaps = 3/149 (2%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
QAP F L+++ + KV P+P + WYR + + + +E +G +
Sbjct: 24429 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24488
Query: 253 -LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AV 310
L I ++ D ++ A N G + L++ +P P+ LE + A+ + G V
Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 24548
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPGDIH 339
+++ G P PV+ W K G++L + H
Sbjct: 24549 SIKIPFSGKPDPVITWQK-GQDLIDNNGH 24576
Score = 49.6 bits (113), Expect = 2e-04
Identities = 42/156 (26%), Positives = 68/156 (43%), Gaps = 17/156 (10%)
Query: 228 WYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLD-QAEWKCVAFNDFGQSVTSCFLK 284
WY +++ P DE +C +++ + L I + D Q E+ C A ND G++ TS L
Sbjct: 4274 WYFENKLVPSDEKFKC---LQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4330
Query: 285 LIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG 344
++ R +E L+ L C++ P +W+K G E+ D I S
Sbjct: 4331 VVKRAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSS 4388
Query: 345 ---------QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC+ASN G + +A+L
Sbjct: 4389 KYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 4424
Score = 48.8 bits (111), Expect = 3e-04
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 14/96 (14%)
Query: 97 KPRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---------- 145
KP + LQ ++ + + F K G P P W KDG+ + G Y+L
Sbjct: 26354 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413
Query: 146 ---TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQN 178
T T+ G Y C KN G SSS +LT++ I++
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26449
Score = 48.4 bits (110), Expect = 4e-04
Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 15/79 (18%)
Query: 111 EGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TGTNSL----------GSYC 155
EG+ V+F CK+ G+P P ++W+KDG+ +K G+ YQ+ G SL G Y
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1317
Query: 156 CIAKNCMGQASSSAELTVE 174
A N G A S +L VE
Sbjct: 1318 AFASNIKGNAICSGKLYVE 1336
Score = 47.6 bits (108), Expect = 7e-04
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQLTG 147
P F++ LQ++ +G V + +V G P PV+ +++DG E++ GD+Y L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVE 174
+ G+Y A N +G+A+S+AEL V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 47.6 bits (108), Expect = 7e-04
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P V GLK+V E ++ P P++ WYR+D ++ S + + G+ L
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQI-TFQSGIARLM 955
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
I+ D + C A N+ G TSC+L + + ++K
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 994
Score = 46.8 bits (106), Expect = 0.001
Identities = 54/230 (23%), Positives = 105/230 (45%), Gaps = 21/230 (9%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+F+C++ PV W+ G++L+P D ++ + + ++ + + +LT +
Sbjct: 5717 TFDCELSYEDIPV-EWYLKGKKLEPSD--KVVPRSEGKVHTLTLRDVKLEDAGEVQLTAK 5773
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLL-WYRDDQ 233
D + N LF K +F L+ + ++E ++ + E + + W+++
Sbjct: 5774 DFKTHAN------LFVKEPPVEFTKPLE--DQTVEEGATAVLECEVSRENAKVKWFKNGT 5825
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ +S + + + R V L I D + C A DF TSC L ++P H +
Sbjct: 5826 EILKSKKYEIVADGR-VRKLVIHDCTPEDIKTYTCDA-KDFK---TSCNLN-VVPPHVEF 5879
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
R L +LQ + ++ EC+ + +KW+KDG E+K G + IIS
Sbjct: 5880 LRPLTDLQ--VREKEMARFECE-LSRENAKVKWFKDGAEIKKGKKYDIIS 5926
Score = 46.8 bits (106), Expect = 0.001
Identities = 34/145 (23%), Positives = 63/145 (43%), Gaps = 5/145 (3%)
Query: 190 SKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG 249
+ +AP +K V K+ E + + ++ P P + WYR + + +S + + + R
Sbjct: 24031 TSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR- 24089
Query: 250 VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL-IIPRHYKKPRFLENLQAILSDEG 308
L + E D+ + C+A N+ G+ TS L L P+ + E +
Sbjct: 24090 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVG--S 24147
Query: 309 AVNLECKVIGVPQPVLKWYKDGEEL 333
+ L IG P P + W+ G++L
Sbjct: 24148 TLRLHVMYIGRPVPAMTWF-HGQKL 24171
Score = 45.6 bits (103), Expect = 0.003
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 15/91 (16%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL------TGT-- 148
P F++ L+ + +GL + FE VVG P P ++WFK+ ++L Y + +GT
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 149 ------NSLGSYCCIAKNCMGQASSSAELTV 173
G Y C A+N +G+++ +AEL V
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 45.6 bits (103), Expect = 0.003
Identities = 54/226 (23%), Positives = 100/226 (44%), Gaps = 19/226 (8%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSA 169
E+ FEC+V P W K QE+ D ++L + + + K+ + +
Sbjct: 5356 EKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGT--KHSMVIKSAAFEDEAKY 5412
Query: 170 ELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWY 229
ED + +L + KF+ LK V AK E FT++++ + W+
Sbjct: 5413 MFEAED------KHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELS-HDNIRVKWF 5465
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
++DQ + ++R ++E + + L D ++ + A G S + L ++
Sbjct: 5466 KNDQRL-HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAM---GMS-SEAKLTVLEGD 5520
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
Y + L++ + DE V L+C++ PV KW+KDG+E+KP
Sbjct: 5521 PYFTGK-LQDYTGVEKDE--VILQCEISKADAPV-KWFKDGKEIKP 5562
Score = 45.2 bits (102), Expect = 0.004
Identities = 47/211 (22%), Positives = 85/211 (40%), Gaps = 23/211 (10%)
Query: 98 PRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQL-- 145
P F++ + A ++ + + V+G P P + WF +G L P GD + L
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTV-------EDIQNQLNEEEKLQLFSKNQAPK 196
T G Y C+A N G+ SA L + +D + + + L+ P
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
F+ LK + P F V P P++ W+++++ + S + G +
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3636
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + C A N G+S +C +L++
Sbjct: 3637 DPQREDSGLYICKAENMLGES--TCAAELLV 3665
Score = 44.8 bits (101), Expect = 0.005
Identities = 34/159 (21%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Query: 87 SHPTVPKN---YRKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQE-LKPGD 141
S P PK+ + P F E L+ + + + + CKV G P P++ W++ G+E + G
Sbjct: 24417 SEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGL 24476
Query: 142 VYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF--SKNQAPKFVH 199
Y++ G + I + ++ ++ + ++ L++ +K PK +
Sbjct: 24477 KYRIQEFKG-GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLE 24535
Query: 200 GLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES 238
G+ +V A E I + P+P + W + +D +
Sbjct: 24536 GMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNN 24574
Score = 43.2 bits (97), Expect = 0.015
Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 9/73 (12%)
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTCSL--------GTYTCEAS 359
A L C+++G P P +KWY+ G+EL +++ S G+ T ++ G YTC A+
Sbjct: 24052 AAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIAT 24111
Query: 360 NCMGVAASSASLL 372
N +G +S+ LL
Sbjct: 24112 NEVGEVETSSKLL 24124
Score = 40.3 bits (90), Expect = 0.11
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVF 251
+ AP F+ +S + FT +++ P P + W++++ P+ SS + + R V+
Sbjct: 26634 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR-SRNVY 26692
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
L+I+ D ++ A N GQ + L +++P
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQCSATASL-MVLP 26728
Score = 39.5 bits (88), Expect = 0.19
Identities = 30/130 (23%), Positives = 58/130 (44%), Gaps = 14/130 (10%)
Query: 59 GWTDLANFGLELFVEVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEG-LVSFE 117
G + + +F E + + S T + P + ++ V T+ G
Sbjct: 23997 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 24056
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTG---TNSL----------GSYCCIAKNCMGQ 164
C++VG P P + W++ G+EL Y+++ T++L G Y CIA N +G+
Sbjct: 24057 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24116
Query: 165 ASSSAELTVE 174
+S++L ++
Sbjct: 24117 VETSSKLLLQ 24126
Score = 39.5 bits (88), Expect = 0.19
Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH---YKKPRFLENLQAI-LSDEGAV 310
I+ LE+ E++ N G+S S + I P+ + P F E L+ + + +
Sbjct: 24393 IEGLEY----EFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA 24448
Query: 311 NLECKVIGVPQPVLKWYKDGEEL 333
L CKV G P+P++KWY+ G+E+
Sbjct: 24449 TLVCKVTGHPKPIVKWYRQGKEI 24471
Score = 39.5 bits (88), Expect = 0.19
Identities = 96/465 (20%), Positives = 174/465 (37%), Gaps = 37/465 (7%)
Query: 2500 LEVMAPH-LTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVEQDL 2558
L A H +T K K EI D V++++ E+ ++QKA V E+ +
Sbjct: 26104 LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26163
Query: 2559 NSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKITDNL 2618
SP + K+P V + + + K + E K + +L
Sbjct: 26164 TSPPRV------KSPEPRVKSPEAVKSPKRVKSPEPSHPK--AVSPTETKPTPREKVQHL 26215
Query: 2619 FSIEAAQSIEVKEDFSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPTNINLLVDD 2678
+ A I +K+ + +T V+ESS +R E D L ++
Sbjct: 26216 -PVSAPPKIT-----QFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDG-----KKLKEN 26264
Query: 2679 SLLEIDKAVKSTEALK--NIPQRDLAENEQQLGEDTTGSKQKVVELPDTIDDVSQDMI-V 2735
+ + T LK N+ + D E ++ + SK + + + + + +
Sbjct: 26265 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKI 26324
Query: 2736 EHLPTSEVKLLEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVD--LVKIAGEPEI 2793
S+ K E + E E + S V V +T + SV VK GEP
Sbjct: 26325 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 26384
Query: 2794 KSKLVEELQTIADSKSQKMIE-------ESTTRETVESPLITTGKTTETPNDITSMNVGE 2846
+ ++ + I K+ E E +T +S L T + +S +
Sbjct: 26385 TAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444
Query: 2847 TEKQRKESITELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEV 2906
+ E+ QK+S+ T + V V +EI + L S+EIK ++ + K L E
Sbjct: 26445 KAIKDTEAQKVSTQKTSEITPQKKAV--VQEEISQKALRSEEIKMSEAKSQEKLALKEEA 26502
Query: 2907 NLPLVTGHETIQTLNSNLENEMC--ESLKIEQAVSAETTESTVES 2949
+ L++ E ++ ++LE + E K QA T + +++
Sbjct: 26503 SKVLIS-EEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKA 26546
Score = 39.5 bits (88), Expect = 0.19
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 10/89 (11%)
Query: 293 KPRFLENLQ-AILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG---- 347
KP + LQ +S + K G P+P W KDG+ + G +++ + G
Sbjct: 26354 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413
Query: 348 -----TCSLGTYTCEASNCMGVAASSASL 371
T G YTC N G +SS L
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKL 26442
Score = 38.7 bits (86), Expect = 0.33
Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
S A L + + E Q F+ + AP+ ++S + RF + V P
Sbjct: 25848 SMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAE 25907
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+ WY + + ESS+ H GV L+I D ++ V N G++
Sbjct: 25908 VKWYHNGVELQESSKIHY-TNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA 25958
Score = 38.3 bits (85), Expect = 0.43
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P + L+ V EG V+ EC + G+P+P ++W+++ +++ +Q+T + +
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 152 --------GSYCCIAKNCMGQASSSAELTVE 174
G + C A N G S+S L V+
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Score = 38.3 bits (85), Expect = 0.43
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 14/94 (14%)
Query: 292 KKPRFLENLQAI-LSDEGAVNLECKVIGVPQP--VLKWYKDGEELKPGDIHRIISGQDGT 348
+KP F + L ++ L G + EC++ + P V++W DG+ L+ + R+I+ + G
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMIN-EFGY 1713
Query: 349 CSL----------GTYTCEASNCMGVAASSASLL 372
CSL G TC A+N G +SA+L+
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1747
Score = 38.3 bits (85), Expect = 0.43
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
IAKN G S ++ T + +++++L + PKF ++ E FR
Sbjct: 17099 IAKNAAGAISKPSDST-----GPITAKDEVELPRISMDPKF---RDTIVVNAGETFRLEA 17150
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHL 243
V P P++ W R D+ ++ES+RC +
Sbjct: 17151 DVHGKPLPTIEWLRGDKEIEESARCEI 17177
Score = 37.9 bits (84), Expect = 0.57
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P + L+ + EG +V LEC + G P P + WY++ +++ I I+ Q G L
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITFQSGIARLM 955
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G +TC A N G ++S L
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYL 984
Score = 37.9 bits (84), Expect = 0.57
Identities = 35/160 (21%), Positives = 70/160 (43%), Gaps = 12/160 (7%)
Query: 90 TVPKNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT 148
T K +KP + + V EG + F C+V G+P P ++W+ +GQ ++ +++
Sbjct: 1787 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD 1846
Query: 149 NSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G + +C + ++T E+ + + + KL++ + +SV +
Sbjct: 1847 ---GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED-------FRSVLRRA 1896
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
EP R V P + + D+PVD + + K +R
Sbjct: 1897 PEP-RPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKR 1935
Score = 37.5 bits (83), Expect = 0.75
Identities = 82/377 (21%), Positives = 158/377 (41%), Gaps = 36/377 (9%)
Query: 2695 NIPQRD-----LAENEQQLGEDTTGSKQKVV-ELPDTIDDVSQDMIVEHLPTSEVKL-LE 2747
N PQR+ + + E LGE T ++ V+ E D D + P + L+
Sbjct: 3636 NDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLK 3695
Query: 2748 GQLLAA--EENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKSKLVEELQTIA 2805
G + A E ++ +K +++ TE ++ + IA E+ S+L Q +
Sbjct: 3696 GPAVEALDSEQEIATFVKDTILKAALITE---ENQQLSYEHIAKANELSSQLPLGAQELQ 3752
Query: 2806 DSKSQKMIEESTTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESITELNQKSSDF 2865
Q + +TRE L G P S N+ Q +++ ++ +
Sbjct: 3753 SILEQDKLTPESTREF----LCINGSIHFQPLKEPSPNLQLQIVQSQKTFSKEGILMPEE 3808
Query: 2866 TKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHETIQTLNSNLE 2925
++Q+++SD +++I + ++I + L E N P + + + +++
Sbjct: 3809 PETQAVLSD-TEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSSIEPPMHSYLTSVA 3867
Query: 2926 NEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKKDQAESSNSQTA--ENIVR 2983
E+ SLK E+ VS E V Q+ ++ L ++S+ L + ES S +
Sbjct: 3868 EEVL-SLK-EKTVSDTNREQRVTLQKQEAQSAL-ILSQSLAEGHVESLQSPDVMISQVNY 3924
Query: 2984 EIVVTSEITALETLGL------PLERSGNDGDL-VEL-------LSIETKQITVEPRATT 3029
E +V SE + E + PLE +G D + +E L++E KQ+ ++ +
Sbjct: 3925 EPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEKQVLLKEEHSD 3984
Query: 3030 YEVVAEQQVVPSGQQPV 3046
V+ Q++ S ++PV
Sbjct: 3985 NVVMPPDQIIESKREPV 4001
Score = 37.5 bits (83), Expect = 0.75
Identities = 24/108 (22%), Positives = 43/108 (39%)
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDD 232
V + + EK+Q + PK LK+ +K ++ ++ + WY+D
Sbjct: 26199 VSPTETKPTPREKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDG 26258
Query: 233 QPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTS 280
+ + E+ G + L I L DQ E+ C + G S T+
Sbjct: 26259 KKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTN 26306
Score = 37.1 bits (82), Expect = 1.00
Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 14/104 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL-- 145
P F+ ++ EG V F C++ G P+P + WFK+ + + +VY L
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26696
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQ 187
+ G Y AKN GQ S++A L V + + + E L+
Sbjct: 26697 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLR 26740
Score = 36.3 bits (80), Expect = 1.7
Identities = 41/148 (27%), Positives = 62/148 (41%), Gaps = 13/148 (8%)
Query: 238 SSRCHLGKEERGVFFLDIQAL-EFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
S+ C+L + F + A+ E E + V D + TS + P P F
Sbjct: 979 STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1038
Query: 297 LEN-LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL--- 351
+ + L + G+V C+V G P+P + W K G L G +++ + Q G C L
Sbjct: 1039 ITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVIS 1098
Query: 352 -------GTYTCEASNCMGVAASSASLL 372
G YT N G ++SASLL
Sbjct: 1099 MTFADDAGEYTIVVRNKHGETSASASLL 1126
Score = 36.3 bits (80), Expect = 1.7
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V F + G P P W DG E+K + Y + T++ S I KNC+ + + ++TV
Sbjct: 11031 VRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE-TDNFSSVLTI-KNCLRRDTGEYQITV 11088
Query: 174 ED 175
+
Sbjct: 11089 SN 11090
Score = 35.5 bits (78), Expect = 3.0
Identities = 36/181 (19%), Positives = 70/181 (38%), Gaps = 14/181 (7%)
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
S + I+E R +K I + W + + S G L I+ D
Sbjct: 26548 STQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQT-LTIKQASHRD 26606
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PRFLENLQAILSDEGA-VNLECKVIGVP 320
+ C++ G + C L + + P F+ ++ +EG V C++ G P
Sbjct: 26607 EGILTCISKTKEG--IVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEP 26664
Query: 321 QPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
P ++W+K+ + + +++ + G YT +A N G +++ASL
Sbjct: 26665 SPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 26724
Query: 372 L 372
+
Sbjct: 26725 M 26725
Score = 35.1 bits (77), Expect = 4.0
Identities = 59/259 (22%), Positives = 106/259 (40%), Gaps = 30/259 (11%)
Query: 90 TVPKNYRKPRFMENLQAV----LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
T K KPR + LQ + + E +V E KV + W KDGQE++P D +
Sbjct: 2299 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHI 2357
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
S+ + ++ + + + T+ + L+ ++ ++S + + LK V
Sbjct: 2358 VIDKQ--SHMLLIEDMTKEDAGNYSFTIPAL--GLSTSGRVSVYSVD----VITPLKDVN 2409
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL---GKEERGVFFLDIQALEFLD 262
KV++P S+ WY +D+ + R G ++R L I D
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQR----LVINRTHASD 2465
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQP 322
+ +K + G+ T+C L + K R L +L + +E G+
Sbjct: 2466 EGPYKLIV----GRVETNCNLSV---EKIKIIRGLRDLTCTETQNVVFEVELSHSGI--D 2516
Query: 323 VLKWYKDGEELKPGDIHRI 341
VL +KD +E+KP ++I
Sbjct: 2517 VLWNFKD-KEIKPSSKYKI 2534
Score = 35.1 bits (77), Expect = 4.0
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 22/228 (9%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC+V P W +DG+ L TN++ S K + A++ + E
Sbjct: 2593 FECEVAN-PDSKGEWLRDGKHLPL--------TNNIRSESDGHKRRLIIAATKLDDIGEY 2643
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+ +L K +A K LK++ + FT+++ P + W ++ V
Sbjct: 2644 TYKVATSKTSAKL--KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV-V 2700
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
ES+ + + ++ L I+ +D++ + F G+ S L + + KKP+
Sbjct: 2701 LESNEKYAISVKGTIYSLRIKNCAIVDESVY---GFR-LGRLGASARLHVETVKIIKKPK 2756
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
+ L+ V E V PV KW+ E+KP D HR++S
Sbjct: 2757 DVTALE-----NATVAFEVSVSHDTVPV-KWFHKSVEIKPSDKHRLVS 2798
Score = 34.7 bits (76), Expect = 5.3
Identities = 12/29 (41%), Positives = 20/29 (68%)
Query: 120 VVGFPTPVLSWFKDGQELKPGDVYQLTGT 148
++G P P SW K G++++P D+ Q+T T
Sbjct: 13906 ILGKPLPKSSWSKAGKDIRPSDITQITST 13934
Score = 34.3 bits (75), Expect = 7.0
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 9/72 (12%)
Query: 310 VNLECKVIGVPQPVLKWYKDGEELKPGD--------IHRIISGQDGT-CSLGTYTCEASN 360
+ +E VIG P+P + W KDGE LK ++ ++G G YT A+N
Sbjct: 17832 LKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATN 17891
Query: 361 CMGVAASSASLL 372
G A + S++
Sbjct: 17892 SAGTATENLSVI 17903
Score = 33.9 bits (74), Expect = 9.3
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 20/168 (11%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL------- 151
R +E L+ L L F C++ P WFK G+E+ D + + +
Sbjct: 4341 RKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR 4398
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G Y C A N G S +A LTV + + KL L + PK LKSV
Sbjct: 4399 TQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVRKL-LPERKPEPKEEVVLKSVL 4456
Query: 206 AK---IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV 250
K +EP K+ +P++ +PV+E + K ER +
Sbjct: 4457 RKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKI 4504
Score = 33.9 bits (74), Expect = 9.3
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 9/72 (12%)
Query: 303 ILSDEGAVNLECKVIGVPQPVLKWYKDGEEL--------KPGDIHRIISGQDGT-CSLGT 353
IL A LE V G P P ++W KDG+EL K D + +D T G
Sbjct: 14975 ILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGA 15034
Query: 354 YTCEASNCMGVA 365
YT A+N G A
Sbjct: 15035 YTLTATNPGGFA 15046
>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
Length = 4650
Score = 85.4 bits (202), Expect = 3e-15
Identities = 74/277 (26%), Positives = 130/277 (46%), Gaps = 36/277 (12%)
Query: 104 LQAVLTEEGLVSFECKVVGFPTPV-LSWFKDGQELKPGDVYQLTGTNSL----------- 151
+ AV E G V + CK+ + ++W+ ++L+ + Y++T + +
Sbjct: 2802 MHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 2861
Query: 152 --GSYCCIAKNCMGQASSSAELTVEDIQNQLN-----EEEKLQLFSKN-----QAPKFVH 199
G+Y C N G+ SS AEL V+ ++ + +K++ + + P+F
Sbjct: 2862 DDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTL 2921
Query: 200 GLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD--ESSRCHLGKEERGVFFLDIQA 257
L + A + E RF + + + PEP + WY+ Q + ++ + + + ++G++ L I +
Sbjct: 2922 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 2981
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK------KPRFLENLQAILSDEG-AV 310
+ D AE+ VA N +G+ SC KL + H +P F L EG +V
Sbjct: 2982 VTTDDDAEYTVVARNKYGED--SCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSV 3039
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQD 346
E +V G+P P LKW KDG+ L G +I I G D
Sbjct: 3040 CFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD 3076
Score = 59.7 bits (138), Expect = 2e-07
Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 33/238 (13%)
Query: 79 KSIKMIHNSHPTVPKNYRKPRF---MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQ 135
+++K I T+ R P F + N A + E V F + P P ++W+K GQ
Sbjct: 2898 RTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGEN--VRFGVTITVHPEPHVTWYKSGQ 2955
Query: 136 ELKPGD------------VYQLT----GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQ 179
++KPGD +YQLT T+ Y +A+N G+ S A+LTV
Sbjct: 2956 KIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----T 3010
Query: 180 LNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS 239
L+ P F L + E + + F I+V+ P P+L W +D QP+
Sbjct: 3011 LHPPPT----DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGP 3066
Query: 240 RCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR-HYKKPRF 296
+ E + L I+ D ++ A N G TSC L + R YKK F
Sbjct: 3067 NIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGS--TSCQAHLQVERLRYKKQEF 3122
Score = 52.4 bits (120), Expect = 2e-05
Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 3/124 (2%)
Query: 162 MGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP 221
+ + S + T E + E + + S P V GL+ D +F +K
Sbjct: 4048 ISETKKSDQKTTESTVTRKTEPKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGE 4105
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P+ +W +D + + + + L E++G FFL+I + D + C N G +SC
Sbjct: 4106 PRPTAIWTKDGKAITQGGKYKL-SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSC 4164
Query: 282 FLKL 285
L +
Sbjct: 4165 KLTI 4168
Score = 50.0 bits (114), Expect = 1e-04
Identities = 37/149 (24%), Positives = 68/149 (45%), Gaps = 3/149 (2%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
QAP F L+++ + KV P+P + WYR + + + +E +G +
Sbjct: 2153 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 2212
Query: 253 -LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AV 310
L I ++ D ++ A N G + L++ +P P+ LE + A+ + G V
Sbjct: 2213 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 2272
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPGDIH 339
+++ G P PV+ W K G++L + H
Sbjct: 2273 SIKIPFSGKPDPVITWQK-GQDLIDNNGH 2300
Score = 48.8 bits (111), Expect = 3e-04
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 14/96 (14%)
Query: 97 KPRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---------- 145
KP + LQ ++ + + F K G P P W KDG+ + G Y+L
Sbjct: 4078 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 4137
Query: 146 ---TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQN 178
T T+ G Y C KN G SSS +LT++ I++
Sbjct: 4138 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 4173
Score = 46.8 bits (106), Expect = 0.001
Identities = 34/145 (23%), Positives = 63/145 (43%), Gaps = 5/145 (3%)
Query: 190 SKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG 249
+ +AP +K V K+ E + + ++ P P + WYR + + +S + + + R
Sbjct: 1755 TSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR- 1813
Query: 250 VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL-IIPRHYKKPRFLENLQAILSDEG 308
L + E D+ + C+A N+ G+ TS L L P+ + E +
Sbjct: 1814 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVG--S 1871
Query: 309 AVNLECKVIGVPQPVLKWYKDGEEL 333
+ L IG P P + W+ G++L
Sbjct: 1872 TLRLHVMYIGRPVPAMTWF-HGQKL 1895
Score = 44.8 bits (101), Expect = 0.005
Identities = 34/159 (21%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Query: 87 SHPTVPKN---YRKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQE-LKPGD 141
S P PK+ + P F E L+ + + + + CKV G P P++ W++ G+E + G
Sbjct: 2141 SEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGL 2200
Query: 142 VYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF--SKNQAPKFVH 199
Y++ G + I + ++ ++ + ++ L++ +K PK +
Sbjct: 2201 KYRIQEFKG-GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLE 2259
Query: 200 GLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES 238
G+ +V A E I + P+P + W + +D +
Sbjct: 2260 GMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNN 2298
Score = 43.2 bits (97), Expect = 0.015
Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 9/73 (12%)
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTCSL--------GTYTCEAS 359
A L C+++G P P +KWY+ G+EL +++ S G+ T ++ G YTC A+
Sbjct: 1776 AAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIAT 1835
Query: 360 NCMGVAASSASLL 372
N +G +S+ LL
Sbjct: 1836 NEVGEVETSSKLL 1848
Score = 39.5 bits (88), Expect = 0.19
Identities = 30/130 (23%), Positives = 58/130 (44%), Gaps = 14/130 (10%)
Query: 59 GWTDLANFGLELFVEVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEG-LVSFE 117
G + + +F E + + S T + P + ++ V T+ G
Sbjct: 1721 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 1780
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTG---TNSL----------GSYCCIAKNCMGQ 164
C++VG P P + W++ G+EL Y+++ T++L G Y CIA N +G+
Sbjct: 1781 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 1840
Query: 165 ASSSAELTVE 174
+S++L ++
Sbjct: 1841 VETSSKLLLQ 1850
Score = 39.5 bits (88), Expect = 0.19
Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH---YKKPRFLENLQAI-LSDEGAV 310
I+ LE+ E++ N G+S S + I P+ + P F E L+ + + +
Sbjct: 2117 IEGLEY----EFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA 2172
Query: 311 NLECKVIGVPQPVLKWYKDGEEL 333
L CKV G P+P++KWY+ G+E+
Sbjct: 2173 TLVCKVTGHPKPIVKWYRQGKEI 2195
Score = 39.5 bits (88), Expect = 0.19
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 10/89 (11%)
Query: 293 KPRFLENLQ-AILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG---- 347
KP + LQ +S + K G P+P W KDG+ + G +++ + G
Sbjct: 4078 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 4137
Query: 348 -----TCSLGTYTCEASNCMGVAASSASL 371
T G YTC N G +SS L
Sbjct: 4138 IHKTDTSDSGLYTCTVKNSAGSVSSSCKL 4166
Score = 39.5 bits (88), Expect = 0.19
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVF 251
+ AP F+ +S + FT +++ P P + W++++ P+ SS + + R V+
Sbjct: 4358 SDAPAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISR-SRNVY 4416
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
L+I+ D ++ A N GQ + L +++P
Sbjct: 4417 SLEIRNASVSDSGKYTIKAKNFRGQCSATASL-MVLP 4452
Score = 38.7 bits (86), Expect = 0.33
Identities = 96/465 (20%), Positives = 174/465 (37%), Gaps = 37/465 (7%)
Query: 2500 LEVMAPH-LTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVEQDL 2558
L A H +T K K EI D V++++ E+ ++QKA V E+ +
Sbjct: 3828 LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 3887
Query: 2559 NSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKITDNL 2618
SP + K+P V + + + K + E K + +L
Sbjct: 3888 TSPPRV------KSPEPRVKSPEAVKSPKRVKSPEPSHPK--AVSPTETKPTPIEKVQHL 3939
Query: 2619 FSIEAAQSIEVKEDFSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPTNINLLVDD 2678
+ A I +K+ + +T V+ESS +R E D L ++
Sbjct: 3940 -PVSAPPKIT-----QFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDG-----KKLKEN 3988
Query: 2679 SLLEIDKAVKSTEALK--NIPQRDLAENEQQLGEDTTGSKQKVVELPDTIDDVSQDMI-V 2735
+ + T LK N+ + D E ++ + SK + + + + + +
Sbjct: 3989 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKI 4048
Query: 2736 EHLPTSEVKLLEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVD--LVKIAGEPEI 2793
S+ K E + E E + S V V +T + SV VK GEP
Sbjct: 4049 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 4108
Query: 2794 KSKLVEELQTIADSKSQKMIE-------ESTTRETVESPLITTGKTTETPNDITSMNVGE 2846
+ ++ + I K+ E E +T +S L T + +S +
Sbjct: 4109 TAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 4168
Query: 2847 TEKQRKESITELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEV 2906
+ E+ QK+S+ T + V V +EI + L S+EIK ++ + K L E
Sbjct: 4169 KAIKDTEAQKVSTQKTSEITPQKKAV--VQEEISQKALRSEEIKMSEAKSQEKLALKEEA 4226
Query: 2907 NLPLVTGHETIQTLNSNLENEMC--ESLKIEQAVSAETTESTVES 2949
+ L++ E ++ ++LE + E K QA T + +++
Sbjct: 4227 SKVLIS-EEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKA 4270
Score = 38.3 bits (85), Expect = 0.43
Identities = 27/111 (24%), Positives = 44/111 (39%), Gaps = 1/111 (0%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
S A L + + E Q F+ + AP+ ++S + RF + V P
Sbjct: 3572 SMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAE 3631
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+ WY + + ESS+ H GV L+I D ++ V N G+
Sbjct: 3632 VKWYHNGVELQESSKIHY-TNTSGVLTLEILDCHTDDSGTYRAVCTNYKGE 3681
Score = 37.1 bits (82), Expect = 1.00
Identities = 23/97 (23%), Positives = 40/97 (41%)
Query: 184 EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
EK+Q + PK LK+ +K ++ ++ + WY+D + + E+
Sbjct: 3934 EKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQF 3993
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTS 280
G + L I L DQ E+ C + G S T+
Sbjct: 3994 HYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTN 4030
>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
Length = 3100
Score = 85.4 bits (202), Expect = 3e-15
Identities = 74/277 (26%), Positives = 130/277 (46%), Gaps = 36/277 (12%)
Query: 104 LQAVLTEEGLVSFECKVVGFPTPV-LSWFKDGQELKPGDVYQLTGTNSL----------- 151
+ AV E G V + CK+ + ++W+ ++L+ + Y++T + +
Sbjct: 2802 MHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 2861
Query: 152 --GSYCCIAKNCMGQASSSAELTVEDIQNQLN-----EEEKLQLFSKN-----QAPKFVH 199
G+Y C N G+ SS AEL V+ ++ + +K++ + + P+F
Sbjct: 2862 DDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTL 2921
Query: 200 GLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD--ESSRCHLGKEERGVFFLDIQA 257
L + A + E RF + + + PEP + WY+ Q + ++ + + + ++G++ L I +
Sbjct: 2922 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 2981
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK------KPRFLENLQAILSDEG-AV 310
+ D AE+ VA N +G+ SC KL + H +P F L EG +V
Sbjct: 2982 VTTDDDAEYTVVARNKYGED--SCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSV 3039
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQD 346
E +V G+P P LKW KDG+ L G +I I G D
Sbjct: 3040 CFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD 3076
Score = 50.8 bits (116), Expect = 8e-05
Identities = 56/213 (26%), Positives = 88/213 (41%), Gaps = 30/213 (14%)
Query: 79 KSIKMIHNSHPTVPKNYRKPRF---MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQ 135
+++K I T+ R P F + N A + E V F + P P ++W+K GQ
Sbjct: 2898 RTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGEN--VRFGVTITVHPEPHVTWYKSGQ 2955
Query: 136 ELKPGD------------VYQLT----GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQ 179
++KPGD +YQLT T+ Y +A+N G+ S A+LTV
Sbjct: 2956 KIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----T 3010
Query: 180 LNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS 239
L+ P F L + E + + F I+V+ P P+L W +D QP+
Sbjct: 3011 LHPPPT----DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGP 3066
Query: 240 RCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
+ E + L I+ D ++ A N
Sbjct: 3067 NIEIIHEGLDYYALHIRDTLPEDTGYYRVTATN 3099
Score = 50.0 bits (114), Expect = 1e-04
Identities = 37/149 (24%), Positives = 68/149 (45%), Gaps = 3/149 (2%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
QAP F L+++ + KV P+P + WYR + + + +E +G +
Sbjct: 2153 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 2212
Query: 253 -LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AV 310
L I ++ D ++ A N G + L++ +P P+ LE + A+ + G V
Sbjct: 2213 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 2272
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPGDIH 339
+++ G P PV+ W K G++L + H
Sbjct: 2273 SIKIPFSGKPDPVITWQK-GQDLIDNNGH 2300
Score = 46.8 bits (106), Expect = 0.001
Identities = 34/145 (23%), Positives = 63/145 (43%), Gaps = 5/145 (3%)
Query: 190 SKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG 249
+ +AP +K V K+ E + + ++ P P + WYR + + +S + + + R
Sbjct: 1755 TSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR- 1813
Query: 250 VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL-IIPRHYKKPRFLENLQAILSDEG 308
L + E D+ + C+A N+ G+ TS L L P+ + E +
Sbjct: 1814 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVG--S 1871
Query: 309 AVNLECKVIGVPQPVLKWYKDGEEL 333
+ L IG P P + W+ G++L
Sbjct: 1872 TLRLHVMYIGRPVPAMTWF-HGQKL 1895
Score = 44.8 bits (101), Expect = 0.005
Identities = 34/159 (21%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Query: 87 SHPTVPKN---YRKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQE-LKPGD 141
S P PK+ + P F E L+ + + + + CKV G P P++ W++ G+E + G
Sbjct: 2141 SEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGL 2200
Query: 142 VYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF--SKNQAPKFVH 199
Y++ G + I + ++ ++ + ++ L++ +K PK +
Sbjct: 2201 KYRIQEFKG-GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLE 2259
Query: 200 GLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES 238
G+ +V A E I + P+P + W + +D +
Sbjct: 2260 GMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNN 2298
Score = 43.2 bits (97), Expect = 0.015
Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 9/73 (12%)
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTCSL--------GTYTCEAS 359
A L C+++G P P +KWY+ G+EL +++ S G+ T ++ G YTC A+
Sbjct: 1776 AAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIAT 1835
Query: 360 NCMGVAASSASLL 372
N +G +S+ LL
Sbjct: 1836 NEVGEVETSSKLL 1848
Score = 39.5 bits (88), Expect = 0.19
Identities = 30/130 (23%), Positives = 58/130 (44%), Gaps = 14/130 (10%)
Query: 59 GWTDLANFGLELFVEVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEG-LVSFE 117
G + + +F E + + S T + P + ++ V T+ G
Sbjct: 1721 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 1780
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTG---TNSL----------GSYCCIAKNCMGQ 164
C++VG P P + W++ G+EL Y+++ T++L G Y CIA N +G+
Sbjct: 1781 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 1840
Query: 165 ASSSAELTVE 174
+S++L ++
Sbjct: 1841 VETSSKLLLQ 1850
Score = 39.5 bits (88), Expect = 0.19
Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH---YKKPRFLENLQAI-LSDEGAV 310
I+ LE+ E++ N G+S S + I P+ + P F E L+ + + +
Sbjct: 2117 IEGLEY----EFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA 2172
Query: 311 NLECKVIGVPQPVLKWYKDGEEL 333
L CKV G P+P++KWY+ G+E+
Sbjct: 2173 TLVCKVTGHPKPIVKWYRQGKEI 2195
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 85.4 bits (202), Expect = 3e-15
Identities = 74/277 (26%), Positives = 130/277 (46%), Gaps = 36/277 (12%)
Query: 104 LQAVLTEEGLVSFECKVVGFPTPV-LSWFKDGQELKPGDVYQLTGTNSL----------- 151
+ AV E G V + CK+ + ++W+ ++L+ + Y++T + +
Sbjct: 25078 MHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 25137
Query: 152 --GSYCCIAKNCMGQASSSAELTVEDIQNQLN-----EEEKLQLFSKN-----QAPKFVH 199
G+Y C N G+ SS AEL V+ ++ + +K++ + + P+F
Sbjct: 25138 DDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTL 25197
Query: 200 GLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD--ESSRCHLGKEERGVFFLDIQA 257
L + A + E RF + + + PEP + WY+ Q + ++ + + + ++G++ L I +
Sbjct: 25198 PLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINS 25257
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK------KPRFLENLQAILSDEG-AV 310
+ D AE+ VA N +G+ SC KL + H +P F L EG +V
Sbjct: 25258 VTTDDDAEYTVVARNKYGED--SCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSV 25315
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQD 346
E +V G+P P LKW KDG+ L G +I I G D
Sbjct: 25316 CFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD 25352
Score = 77.0 bits (181), Expect = 1e-12
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVF 251
QAP F L+SV F ++ P P + W+RD Q + S+ + G
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-V 310
L I A+ + + A N GQ+ ++ +L++ P F++ LQ++ +G+ V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTA--ELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 311 NLECKVIGVPQPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNC 361
L+ +V G+P PV+K+Y+DG E+ + GD++ ++ + GTY+ A+N
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 362 MGVAASSASLL 372
+G A S+A LL
Sbjct: 182 VGRATSTAELL 192
Score = 70.5 bits (165), Expect = 9e-11
Identities = 54/198 (27%), Positives = 91/198 (45%), Gaps = 22/198 (11%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+ + L+ V + +P RF ++ P+P + WY+++Q + +C + +
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK--------KPRFLENLQAIL 304
L I+A D A + C A ND+G + TS L + +P P + LQ +
Sbjct: 3251 LLIEAFP-EDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3309
Query: 305 SDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GT 353
+ EG +C+V G V WY +++KP R+ +D T L GT
Sbjct: 3310 TSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGT 3367
Query: 354 YTCEASNCMGVAASSASL 371
YT ASN +G +S+A+L
Sbjct: 3368 YTFVASNAVGQVSSTANL 3385
Score = 66.5 bits (155), Expect = 1e-09
Identities = 50/175 (28%), Positives = 77/175 (44%), Gaps = 3/175 (1%)
Query: 179 QLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES 238
+L E ++ QL + P FV S + + RF +KV P P W+ D Q +
Sbjct: 1396 RLEETDESQL-ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVND 1454
Query: 239 SRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLE 298
+ +E G L I D EW VA N G+S S L + H KP F+E
Sbjct: 1455 YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514
Query: 299 NLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL 351
L+ + EG+ + ++ + G P P + W K+ + + P +I I G G +L
Sbjct: 1515 KLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL 1569
Score = 62.5 bits (145), Expect = 2e-08
Identities = 60/249 (24%), Positives = 106/249 (42%), Gaps = 13/249 (5%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYC 155
P+ E +Q+ +G F +VVG P P W+K+G +++ D +Y +++
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE-- 2089
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
+ ++ + S+S + +I + + L L Q F L+ V AK +
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLITFTQELQDVVAKEKDTMATF 2148
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
P + WY+D V E + + +R V FL I ++ D ++ CV D
Sbjct: 2149 ECETSEPFVKVKWYKDGMEVHEGDKYRM-HSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2207
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELK 334
T+ KLI+ + F++ LQ I + + + LEC ++ KWY + ELK
Sbjct: 2208 VKTTA---KLIVEGAVVE--FVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELK 2261
Query: 335 PGDIHRIIS 343
+ I S
Sbjct: 2262 SNGKYTITS 2270
Score = 60.5 bits (140), Expect = 9e-08
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 2/187 (1%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + LQ+V+ EG +FE + GFP P +SWF+DGQ + + + + S G
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
S L + Q +L + ++ P FV L+S+ + R +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+V P P + +YRD + S + +E ++ L I D + A N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 277 SVTSCFL 283
+ ++ L
Sbjct: 185 ATSTAEL 191
Score = 59.7 bits (138), Expect = 2e-07
Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 33/238 (13%)
Query: 79 KSIKMIHNSHPTVPKNYRKPRF---MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQ 135
+++K I T+ R P F + N A + E V F + P P ++W+K GQ
Sbjct: 25174 RTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGEN--VRFGVTITVHPEPHVTWYKSGQ 25231
Query: 136 ELKPGD------------VYQLT----GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQ 179
++KPGD +YQLT T+ Y +A+N G+ S A+LTV
Sbjct: 25232 KIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV-----T 25286
Query: 180 LNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS 239
L+ P F L + E + + F I+V+ P P+L W +D QP+
Sbjct: 25287 LHPPPT----DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGP 25342
Query: 240 RCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR-HYKKPRF 296
+ E + L I+ D ++ A N G TSC L + R YKK F
Sbjct: 25343 NIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGS--TSCQAHLQVERLRYKKQEF 25398
Score = 59.3 bits (137), Expect = 2e-07
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 6/162 (3%)
Query: 184 EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
+K++L +APK ++S F ++V P+P WY++ ++ S R +
Sbjct: 2021 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2080
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI 303
E V L I+ + D A A N G++ + FL + + + F + LQ +
Sbjct: 2081 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL---LVQAKQLITFTQELQDV 2137
Query: 304 LSDE--GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
++ E EC+ P +KWYKDG E+ GD +R+ S
Sbjct: 2138 VAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHS 2178
Score = 58.4 bits (135), Expect = 4e-07
Identities = 70/255 (27%), Positives = 114/255 (44%), Gaps = 31/255 (12%)
Query: 100 FMENLQAVLTEEG--LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
F + LQ V+ +E + +FEC+ P + W+KDG E+ GD Y++ + + I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKV-HFLSI 2187
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
A + + VED N + +L + +FV L+ +E + E + ++
Sbjct: 2188 LTIDTSDAEDYSCVLVEDE----NVKTTAKLIVEGAVVEFVKELQDIE--VPESYSGELE 2241
Query: 218 VAIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+ PE WY +D + + + + RG L ++ + DQ E+ V
Sbjct: 2242 CIVSPENIEGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFV----IDG 2296
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSD----EG-AVNLECKVIGVPQPVLKWYKDGE 331
T+C LK+ KPR + LQ LSD EG V LE KV + W KDG+
Sbjct: 2297 KKTTCKLKM-------KPRPIAILQG-LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQ 2347
Query: 332 ELKPGD-IHRIISGQ 345
E++P D +H +I Q
Sbjct: 2348 EVQPSDRVHIVIDKQ 2362
Score = 57.2 bits (132), Expect = 9e-07
Identities = 84/302 (27%), Positives = 124/302 (41%), Gaps = 53/302 (17%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ---------------LTGTNSLG 152
L E G V F C+V G P P + W K G L G Y+ +T + G
Sbjct: 1047 LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1106
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA------ 206
Y + +N G+ S+SA L +E+ +L + + ++ + Q FV K E
Sbjct: 1107 EYTIVVRNKHGETSASASL-LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVY 1165
Query: 207 ----KIDEPFRFTIKVAIPPEPSLL-WYRDDQPVDESS-RCHLGKE-ERGVFFLDIQALE 259
K E + I+ + + ++ Y +DQ SS L KE E + ++ L
Sbjct: 1166 SEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELL 1225
Query: 260 FLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D E V ++ ++V S F I K R LE + V CK+ G
Sbjct: 1226 EEDGEEKMAVDISE-SEAVESGFDLRI-----KNYRILEGM--------GVTFHCKMSGY 1271
Query: 320 PQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSA 369
P P + WYKDG+ +K G+ +++ QDG SL G YT ASN G A S
Sbjct: 1272 PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSG 1331
Query: 370 SL 371
L
Sbjct: 1332 KL 1333
Score = 56.8 bits (131), Expect = 1e-06
Identities = 59/251 (23%), Positives = 108/251 (43%), Gaps = 21/251 (8%)
Query: 98 PRFMENLQAVLTEEGLVSFECKVV-GFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ ++ LQ V + G + C V+ G P P +SW+K+ Q L G Y L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 148 TNSLGS----YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+ Y C AKN G A++SA L+VE + ++ ++++ ++ P + L+
Sbjct: 3253 IEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVY----PPAIITPLQD 3307
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+P RF +V+ + + WY D+ + + SR + + L+I D+
Sbjct: 3308 TVTSEGQPARFQCRVS-GTDLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDE 3365
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPV 323
+ VA N GQ ++ L L P R + ++ + + + L + G+
Sbjct: 3366 GTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAE 3425
Query: 324 LKWYKDGEELK 334
L+ K E L+
Sbjct: 3426 LQLSKINETLE 3436
Score = 56.4 bits (130), Expect = 2e-06
Identities = 53/201 (26%), Positives = 84/201 (41%), Gaps = 29/201 (14%)
Query: 97 KPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL 151
KP F+ + EG + F+ KVVG P P WF DGQ++ +++ GT SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL 201
G + +A+N G++S S LTVE +++Q+ P FV L
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVK-------------PMFVEKL 1516
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVFFLDIQALEF 260
K+V K ++ P P ++W ++ + + E +G L I +
Sbjct: 1517 KNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVS 1576
Query: 261 LDQAEWKCVAFNDFGQSVTSC 281
D A + A N G+ T C
Sbjct: 1577 QDSAWYTATAINKAGRDTTRC 1597
Score = 52.4 bits (120), Expect = 2e-05
Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 3/124 (2%)
Query: 162 MGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP 221
+ + S + T E + E + + S P V GL+ D +F +K
Sbjct: 26324 ISETKKSDQKTTESTVTRKTEPKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGE 26381
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P+ +W +D + + + + L E++G FFL+I + D + C N G +SC
Sbjct: 26382 PRPTAIWTKDGKAITQGGKYKL-SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSC 26440
Query: 282 FLKL 285
L +
Sbjct: 26441 KLTI 26444
Score = 52.0 bits (119), Expect = 3e-05
Identities = 47/211 (22%), Positives = 95/211 (45%), Gaps = 36/211 (17%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS--RCHLGKEERGVFF 252
P F+ + + + + + ++ V P+P + W+ + + S+ + ++ +
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL--------------IIPRHYKK----- 293
L LE D+ E+ C+A ND+G+++ S +LK+ + + +K
Sbjct: 3517 L-FTKLE--DEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC 3573
Query: 294 -PRFLENLQAILSDEGAVNL-ECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL 351
P FL+ L+ I +G + E V+G P P + W+K+ ++L + II +G+ +
Sbjct: 3574 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 3633
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G Y C+A N +G + +A LL
Sbjct: 3634 IVNDPQREDSGLYICKAENMLGESTCAAELL 3664
Score = 51.2 bits (117), Expect = 6e-05
Identities = 36/146 (24%), Positives = 65/146 (44%), Gaps = 17/146 (11%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C A N G+ ++SA+LTV K AP ++ +E +
Sbjct: 4310 GEYVCEALNDSGKTATSAKLTVV----------------KRAAPVIKRKIEPLEVALGHL 4353
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
+FT ++ P W++ + + ES +C + + + + L+I + +D E+ C A
Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 4412
Query: 272 NDFGQSVTSCFLKLIIPRHYKKPRFL 297
N++G + L + +P KK R L
Sbjct: 4413 NEYGSVSCTATLTVTVPGGEKKVRKL 4438
Score = 50.0 bits (114), Expect = 1e-04
Identities = 54/217 (24%), Positives = 91/217 (41%), Gaps = 20/217 (9%)
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
SS+E E++ + +E F K P +H V+ +E + +I +
Sbjct: 4216 SSSESGTEEVAT-VKIQEAEGGFIKEDGP-MIH-TPLVDTVSEEGDIVHLTTSITNAKEV 4272
Query: 227 LWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLD-QAEWKCVAFNDFGQSVTSCFL 283
WY +++ P DE +C +++ + L I + D Q E+ C A ND G++ TS L
Sbjct: 4273 NWYFENKLVPSDEKFKC---LQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4329
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
++ R +E L+ L C++ P +W+K G E+ D I S
Sbjct: 4330 TVVKRAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS 4387
Query: 344 G---------QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC+ASN G + +A+L
Sbjct: 4388 SKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 4424
Score = 50.0 bits (114), Expect = 1e-04
Identities = 37/149 (24%), Positives = 68/149 (45%), Gaps = 3/149 (2%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
QAP F L+++ + KV P+P + WYR + + + +E +G +
Sbjct: 24429 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24488
Query: 253 -LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AV 310
L I ++ D ++ A N G + L++ +P P+ LE + A+ + G V
Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 24548
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPGDIH 339
+++ G P PV+ W K G++L + H
Sbjct: 24549 SIKIPFSGKPDPVITWQK-GQDLIDNNGH 24576
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/91 (32%), Positives = 51/91 (56%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQLTG 147
P F++ LQ++ +G V + +V G PTPV+ +++DG E++ GD+Y L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVE 174
+ G+Y A N +G+A+S+AEL V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 48.8 bits (111), Expect = 3e-04
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 14/96 (14%)
Query: 97 KPRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---------- 145
KP + LQ ++ + + F K G P P W KDG+ + G Y+L
Sbjct: 26354 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413
Query: 146 ---TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQN 178
T T+ G Y C KN G SSS +LT++ I++
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26449
Score = 48.4 bits (110), Expect = 4e-04
Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 15/79 (18%)
Query: 111 EGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TGTNSL----------GSYC 155
EG+ V+F CK+ G+P P ++W+KDG+ +K G+ YQ+ G SL G Y
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1317
Query: 156 CIAKNCMGQASSSAELTVE 174
A N G A S +L VE
Sbjct: 1318 AFASNIKGNAICSGKLYVE 1336
Score = 47.6 bits (108), Expect = 7e-04
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P V GLK+V E ++ P P++ WYR+D ++ S + + G+ L
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQI-TFQSGIARLM 955
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
I+ D + C A N+ G TSC+L + + ++K
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 994
Score = 46.8 bits (106), Expect = 0.001
Identities = 54/230 (23%), Positives = 105/230 (45%), Gaps = 21/230 (9%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+F+C++ PV W+ G++L+P D ++ + + ++ + + +LT +
Sbjct: 5717 TFDCELSYEDIPV-EWYLKGKKLEPSD--KVVPRSEGKVHTLTLRDVKLEDAGEVQLTAK 5773
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLL-WYRDDQ 233
D + N LF K +F L+ + ++E ++ + E + + W+++
Sbjct: 5774 DFKTHAN------LFVKEPPVEFTKPLE--DQTVEEGATAVLECEVSRENAKVKWFKNGT 5825
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
+ +S + + + R V L I D + C A DF TSC L ++P H +
Sbjct: 5826 EILKSKKYEIVADGR-VRKLVIHDCTPEDIKTYTCDA-KDFK---TSCNLN-VVPPHVEF 5879
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
R L +LQ + ++ EC+ + +KW+KDG E+K G + IIS
Sbjct: 5880 LRPLTDLQ--VREKEMARFECE-LSRENAKVKWFKDGAEIKKGKKYDIIS 5926
Score = 46.8 bits (106), Expect = 0.001
Identities = 34/145 (23%), Positives = 63/145 (43%), Gaps = 5/145 (3%)
Query: 190 SKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG 249
+ +AP +K V K+ E + + ++ P P + WYR + + +S + + + R
Sbjct: 24031 TSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR- 24089
Query: 250 VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL-IIPRHYKKPRFLENLQAILSDEG 308
L + E D+ + C+A N+ G+ TS L L P+ + E +
Sbjct: 24090 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVG--S 24147
Query: 309 AVNLECKVIGVPQPVLKWYKDGEEL 333
+ L IG P P + W+ G++L
Sbjct: 24148 TLRLHVMYIGRPVPAMTWF-HGQKL 24171
Score = 45.6 bits (103), Expect = 0.003
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 15/91 (16%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL------TGT-- 148
P F++ L+ + +GL + FE VVG P P ++WFK+ ++L Y + +GT
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 149 ------NSLGSYCCIAKNCMGQASSSAELTV 173
G Y C A+N +G+++ +AEL V
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 45.6 bits (103), Expect = 0.003
Identities = 54/226 (23%), Positives = 100/226 (44%), Gaps = 19/226 (8%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSA 169
E+ FEC+V P W K QE+ D ++L + + + K+ + +
Sbjct: 5356 EKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGT--KHSMVIKSAAFEDEAKY 5412
Query: 170 ELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWY 229
ED + +L + KF+ LK V AK E FT++++ + W+
Sbjct: 5413 MFEAED------KHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELS-HDNIRVKWF 5465
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
++DQ + ++R ++E + + L D ++ + A G S + L ++
Sbjct: 5466 KNDQRL-HTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAM---GMS-SEAKLTVLEGD 5520
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
Y + L++ + DE V L+C++ PV KW+KDG+E+KP
Sbjct: 5521 PYFTGK-LQDYTGVEKDE--VILQCEISKADAPV-KWFKDGKEIKP 5562
Score = 45.2 bits (102), Expect = 0.004
Identities = 47/211 (22%), Positives = 85/211 (40%), Gaps = 23/211 (10%)
Query: 98 PRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQL-- 145
P F++ + A ++ + + V+G P P + WF +G L P GD + L
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTV-------EDIQNQLNEEEKLQLFSKNQAPK 196
T G Y C+A N G+ SA L + +D + + + L+ P
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
F+ LK + P F V P P++ W+++++ + S + G +
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3636
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + C A N G+S +C +L++
Sbjct: 3637 DPQREDSGLYICKAENMLGES--TCAAELLV 3665
Score = 44.8 bits (101), Expect = 0.005
Identities = 34/159 (21%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Query: 87 SHPTVPKN---YRKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQE-LKPGD 141
S P PK+ + P F E L+ + + + + CKV G P P++ W++ G+E + G
Sbjct: 24417 SEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGL 24476
Query: 142 VYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLF--SKNQAPKFVH 199
Y++ G + I + ++ ++ + ++ L++ +K PK +
Sbjct: 24477 KYRIQEFKG-GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLE 24535
Query: 200 GLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES 238
G+ +V A E I + P+P + W + +D +
Sbjct: 24536 GMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNN 24574
Score = 43.2 bits (97), Expect = 0.015
Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 9/73 (12%)
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTCSL--------GTYTCEAS 359
A L C+++G P P +KWY+ G+EL +++ S G+ T ++ G YTC A+
Sbjct: 24052 AAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIAT 24111
Query: 360 NCMGVAASSASLL 372
N +G +S+ LL
Sbjct: 24112 NEVGEVETSSKLL 24124
Score = 42.7 bits (96), Expect = 0.020
Identities = 56/221 (25%), Positives = 90/221 (40%), Gaps = 43/221 (19%)
Query: 96 RKPRFMENLQAV-LTEEGLVSFECKV--VGFPTPVLSWFKDGQELKPGD----------- 141
+KP F + L ++ L G FEC++ +G PT V+ W DG+ L+ +
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1714
Query: 142 --VYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEE------------EKLQ 187
Y + + G C A N G +SA L V+D ++ + E E+L+
Sbjct: 1715 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELE 1774
Query: 188 LFS-------------KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + Q P V + V E RF +V P+P + WY + Q
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ +S R + + G+ +LDI + D E K A N G
Sbjct: 1835 IRKSKRFRVRYD--GIHYLDIVDCKSYDTGEVKVTAENPEG 1873
Score = 40.3 bits (90), Expect = 0.11
Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 14/94 (14%)
Query: 292 KKPRFLENLQAI-LSDEGAVNLECKV--IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT 348
+KP F + L ++ L G + EC++ IG P V++W DG+ L+ + R+I+ + G
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN-EFGY 1713
Query: 349 CSL----------GTYTCEASNCMGVAASSASLL 372
CSL G TC A+N G +SA+L+
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1747
Score = 40.3 bits (90), Expect = 0.11
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVF 251
+ AP F+ +S + FT +++ P P + W++++ P+ SS + + R V+
Sbjct: 26634 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR-SRNVY 26692
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
L+I+ D ++ A N GQ + L +++P
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQCSATASL-MVLP 26728
Score = 39.5 bits (88), Expect = 0.19
Identities = 30/130 (23%), Positives = 58/130 (44%), Gaps = 14/130 (10%)
Query: 59 GWTDLANFGLELFVEVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEG-LVSFE 117
G + + +F E + + S T + P + ++ V T+ G
Sbjct: 23997 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 24056
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTG---TNSL----------GSYCCIAKNCMGQ 164
C++VG P P + W++ G+EL Y+++ T++L G Y CIA N +G+
Sbjct: 24057 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24116
Query: 165 ASSSAELTVE 174
+S++L ++
Sbjct: 24117 VETSSKLLLQ 24126
Score = 39.5 bits (88), Expect = 0.19
Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH---YKKPRFLENLQAI-LSDEGAV 310
I+ LE+ E++ N G+S S + I P+ + P F E L+ + + +
Sbjct: 24393 IEGLEY----EFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA 24448
Query: 311 NLECKVIGVPQPVLKWYKDGEEL 333
L CKV G P+P++KWY+ G+E+
Sbjct: 24449 TLVCKVTGHPKPIVKWYRQGKEI 24471
Score = 39.5 bits (88), Expect = 0.19
Identities = 96/465 (20%), Positives = 174/465 (37%), Gaps = 37/465 (7%)
Query: 2500 LEVMAPH-LTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVEQDL 2558
L A H +T K K EI D V++++ E+ ++QKA V E+ +
Sbjct: 26104 LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26163
Query: 2559 NSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKITDNL 2618
SP + K+P V + + + K + E K + +L
Sbjct: 26164 TSPPRV------KSPEPRVKSPEAVKSPKRVKSPEPSHPK--AVSPTETKPTPTEKVQHL 26215
Query: 2619 FSIEAAQSIEVKEDFSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPTNINLLVDD 2678
+ A I +K+ + +T V+ESS +R E D L ++
Sbjct: 26216 -PVSAPPKIT-----QFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDG-----KKLKEN 26264
Query: 2679 SLLEIDKAVKSTEALK--NIPQRDLAENEQQLGEDTTGSKQKVVELPDTIDDVSQDMI-V 2735
+ + T LK N+ + D E ++ + SK + + + + + +
Sbjct: 26265 GHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKI 26324
Query: 2736 EHLPTSEVKLLEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVD--LVKIAGEPEI 2793
S+ K E + E E + S V V +T + SV VK GEP
Sbjct: 26325 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 26384
Query: 2794 KSKLVEELQTIADSKSQKMIE-------ESTTRETVESPLITTGKTTETPNDITSMNVGE 2846
+ ++ + I K+ E E +T +S L T + +S +
Sbjct: 26385 TAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444
Query: 2847 TEKQRKESITELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEV 2906
+ E+ QK+S+ T + V V +EI + L S+EIK ++ + K L E
Sbjct: 26445 KAIKDTEAQKVSTQKTSEITPQKKAV--VQEEISQKALRSEEIKMSEAKSQEKLALKEEA 26502
Query: 2907 NLPLVTGHETIQTLNSNLENEMC--ESLKIEQAVSAETTESTVES 2949
+ L++ E ++ ++LE + E K QA T + +++
Sbjct: 26503 SKVLIS-EEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKA 26546
Score = 39.5 bits (88), Expect = 0.19
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 10/89 (11%)
Query: 293 KPRFLENLQ-AILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG---- 347
KP + LQ +S + K G P+P W KDG+ + G +++ + G
Sbjct: 26354 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 26413
Query: 348 -----TCSLGTYTCEASNCMGVAASSASL 371
T G YTC N G +SS L
Sbjct: 26414 IHKTDTSDSGLYTCTVKNSAGSVSSSCKL 26442
Score = 38.7 bits (86), Expect = 0.33
Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
S A L + + E Q F+ + AP+ ++S + RF + V P
Sbjct: 25848 SMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAE 25907
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+ WY + + ESS+ H GV L+I D ++ V N G++
Sbjct: 25908 VKWYHNGVELQESSKIHY-TNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA 25958
Score = 38.3 bits (85), Expect = 0.43
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P + L+ V EG V+ EC + G+P+P ++W+++ +++ +Q+T + +
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 152 --------GSYCCIAKNCMGQASSSAELTVE 174
G + C A N G S+S L V+
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Score = 38.3 bits (85), Expect = 0.43
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
IAKN G S ++ T + +++++L + PKF ++ E FR
Sbjct: 17099 IAKNAAGAISKPSDST-----GPITAKDEVELPRISMDPKF---RDTIVVNAGETFRLEA 17150
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHL 243
V P P++ W R D+ ++ES+RC +
Sbjct: 17151 DVHGKPLPTIEWLRGDKEIEESARCEI 17177
Score = 37.9 bits (84), Expect = 0.57
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P + L+ + EG +V LEC + G P P + WY++ +++ I I+ Q G L
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITFQSGIARLM 955
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G +TC A N G ++S L
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYL 984
Score = 37.9 bits (84), Expect = 0.57
Identities = 35/160 (21%), Positives = 70/160 (43%), Gaps = 12/160 (7%)
Query: 90 TVPKNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT 148
T K +KP + + V EG + F C+V G+P P ++W+ +GQ ++ +++
Sbjct: 1787 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD 1846
Query: 149 NSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G + +C + ++T E+ + + + KL++ + +SV +
Sbjct: 1847 ---GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED-------FRSVLRRA 1896
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
EP R V P + + D+PVD + + K +R
Sbjct: 1897 PEP-RPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKR 1935
Score = 37.1 bits (82), Expect = 1.00
Identities = 23/97 (23%), Positives = 40/97 (41%)
Query: 184 EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
EK+Q + PK LK+ +K ++ ++ + WY+D + + E+
Sbjct: 26210 EKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQF 26269
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTS 280
G + L I L DQ E+ C + G S T+
Sbjct: 26270 HYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTN 26306
Score = 37.1 bits (82), Expect = 1.00
Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 14/104 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL-- 145
P F+ ++ EG V F C++ G P+P + WFK+ + + +VY L
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26696
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQ 187
+ G Y AKN GQ S++A L V + + + E L+
Sbjct: 26697 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLR 26740
Score = 36.3 bits (80), Expect = 1.7
Identities = 41/148 (27%), Positives = 62/148 (41%), Gaps = 13/148 (8%)
Query: 238 SSRCHLGKEERGVFFLDIQAL-EFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
S+ C+L + F + A+ E E + V D + TS + P P F
Sbjct: 979 STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1038
Query: 297 LEN-LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL--- 351
+ + L + G+V C+V G P+P + W K G L G +++ + Q G C L
Sbjct: 1039 ITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVIS 1098
Query: 352 -------GTYTCEASNCMGVAASSASLL 372
G YT N G ++SASLL
Sbjct: 1099 MTFADDAGEYTIVVRNKHGETSASASLL 1126
Score = 36.3 bits (80), Expect = 1.7
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V F + G P P W DG E+K + Y + T++ S I KNC+ + + ++TV
Sbjct: 11031 VRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE-TDNFSSVLTI-KNCLRRDTGEYQITV 11088
Query: 174 ED 175
+
Sbjct: 11089 SN 11090
Score = 35.5 bits (78), Expect = 3.0
Identities = 36/181 (19%), Positives = 70/181 (38%), Gaps = 14/181 (7%)
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
S + I+E R +K I + W + + S G L I+ D
Sbjct: 26548 STQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQT-LTIKQASHRD 26606
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PRFLENLQAILSDEGA-VNLECKVIGVP 320
+ C++ G + C L + + P F+ ++ +EG V C++ G P
Sbjct: 26607 EGILTCISKTKEG--IVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEP 26664
Query: 321 QPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
P ++W+K+ + + +++ + G YT +A N G +++ASL
Sbjct: 26665 SPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 26724
Query: 372 L 372
+
Sbjct: 26725 M 26725
Score = 35.1 bits (77), Expect = 4.0
Identities = 59/259 (22%), Positives = 106/259 (40%), Gaps = 30/259 (11%)
Query: 90 TVPKNYRKPRFMENLQAV----LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
T K KPR + LQ + + E +V E KV + W KDGQE++P D +
Sbjct: 2299 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHI 2357
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
S+ + ++ + + + T+ + L+ ++ ++S + + LK V
Sbjct: 2358 VIDKQ--SHMLLIEDMTKEDAGNYSFTIPAL--GLSTSGRVSVYSVD----VITPLKDVN 2409
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL---GKEERGVFFLDIQALEFLD 262
KV++P S+ WY +D+ + R G ++R L I D
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQR----LVINRTHASD 2465
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQP 322
+ +K + G+ T+C L + K R L +L + +E G+
Sbjct: 2466 EGPYKLIV----GRVETNCNLSV---EKIKIIRGLRDLTCTETQNVVFEVELSHSGI--D 2516
Query: 323 VLKWYKDGEELKPGDIHRI 341
VL +KD +E+KP ++I
Sbjct: 2517 VLWNFKD-KEIKPSSKYKI 2534
Score = 35.1 bits (77), Expect = 4.0
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 22/228 (9%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC+V P W +DG+ L TN++ S K + A++ + E
Sbjct: 2593 FECEVAN-PDSKGEWLRDGKHLPL--------TNNIRSESDGHKRRLIIAATKLDDIGEY 2643
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+ +L K +A K LK++ + FT+++ P + W ++ V
Sbjct: 2644 TYKVATSKTSAKL--KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV-V 2700
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
ES+ + + ++ L I+ +D++ + F G+ S L + + KKP+
Sbjct: 2701 LESNEKYAISVKGTIYSLRIKNCAIVDESVY---GFR-LGRLGASARLHVETVKIIKKPK 2756
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
+ L+ V E V PV KW+ E+KP D HR++S
Sbjct: 2757 DVTALE-----NATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVS 2798
Score = 34.7 bits (76), Expect = 5.3
Identities = 79/377 (20%), Positives = 155/377 (41%), Gaps = 36/377 (9%)
Query: 2695 NIPQRD-----LAENEQQLGEDTTGSKQKVV-ELPDTIDDVSQDMIVEHLPTSEVKL-LE 2747
N PQR+ + + E LGE T ++ V+ E D D + P + L+
Sbjct: 3636 NDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLK 3695
Query: 2748 GQLLAA--EENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKSKLVEELQTIA 2805
G + A E ++ +K +++ TE ++ + IA E+ S+L Q +
Sbjct: 3696 GPAVEALDSEQEIATFVKDTILKAALITE---ENQQLSYEHIAKANELSSQLPLGAQELQ 3752
Query: 2806 DSKSQKMIEESTTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESITELNQKSSDF 2865
Q + +TRE L G P S N+ Q +++ ++ +
Sbjct: 3753 SILEQDKLTPESTREF----LCINGSIHFQPLKEPSPNLQLQIVQSQKTFSKEGILMPEE 3808
Query: 2866 TKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHETIQTLNSNLE 2925
++Q+++SD +++I + ++I + L E N P + + + +++
Sbjct: 3809 PETQAVLSD-TEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSSIEPPMHSYLTSVA 3867
Query: 2926 NEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKKDQAESSNSQTA--ENIVR 2983
E+ E+ VS E V Q+ ++ L ++S+ L + ES S +
Sbjct: 3868 EEVLSPK--EKTVSDTNREQRVTLQKQEAQSAL-ILSQSLAEGHVESLQSPDVMISQVNY 3924
Query: 2984 EIVVTSEITALETLGL------PLERSGNDGDL-VEL-------LSIETKQITVEPRATT 3029
E +V SE + E + PLE +G D + +E L++E KQ+ ++ +
Sbjct: 3925 EPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEKQVLLKEEHSD 3984
Query: 3030 YEVVAEQQVVPSGQQPV 3046
V+ Q++ S ++PV
Sbjct: 3985 NVVMPPDQIIESKREPV 4001
Score = 34.7 bits (76), Expect = 5.3
Identities = 12/29 (41%), Positives = 20/29 (68%)
Query: 120 VVGFPTPVLSWFKDGQELKPGDVYQLTGT 148
++G P P SW K G++++P D+ Q+T T
Sbjct: 13906 ILGKPLPKSSWSKAGKDIRPSDITQITST 13934
Score = 34.3 bits (75), Expect = 7.0
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 9/72 (12%)
Query: 310 VNLECKVIGVPQPVLKWYKDGEELKPGD--------IHRIISGQDGT-CSLGTYTCEASN 360
+ +E VIG P+P + W KDGE LK ++ ++G G YT A+N
Sbjct: 17832 LKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATN 17891
Query: 361 CMGVAASSASLL 372
G A + S++
Sbjct: 17892 SAGTATENLSVI 17903
Score = 33.9 bits (74), Expect = 9.3
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 20/168 (11%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL------- 151
R +E L+ L L F C++ P WFK G+E+ D + + +
Sbjct: 4341 RKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR 4398
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G Y C A N G S +A LTV + + KL L + PK LKSV
Sbjct: 4399 TQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVRKL-LPERKPEPKEEVVLKSVL 4456
Query: 206 AK---IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV 250
K +EP K+ +P++ +PV+E + K ER +
Sbjct: 4457 RKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKI 4504
Score = 33.9 bits (74), Expect = 9.3
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 9/72 (12%)
Query: 303 ILSDEGAVNLECKVIGVPQPVLKWYKDGEEL--------KPGDIHRIISGQDGT-CSLGT 353
IL A LE V G P P ++W KDG+EL K D + +D T G
Sbjct: 14975 ILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGA 15034
Query: 354 YTCEASNCMGVA 365
YT A+N G A
Sbjct: 15035 YTLTATNPGGFA 15046
>U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphatase
sigma protein.
Length = 1948
Score = 84.6 bits (200), Expect = 5e-15
Identities = 72/294 (24%), Positives = 126/294 (42%), Gaps = 20/294 (6%)
Query: 98 PRFM-ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
PRF+ E + G+ SF C+ G P P ++W K G+++ + S G+
Sbjct: 33 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK-FVHGLKSVEAKIDEPFRFT 215
I + + E ++ ++ KL + ++Q P F + + K+ E R
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152
Query: 216 IKVAIP---PEPSLLWYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQA 264
+ P+P + W++D PVD S+ K+ R F L I++ E DQ
Sbjct: 153 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQG 212
Query: 265 EWKCVAFNDFG---QSVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVP 320
+++CVA N G S + +++ + PRF + + + G VN+ C +G P
Sbjct: 213 KYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSP 272
Query: 321 QPVLKWYKDGEELKPGD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
P +KW + E+L P D + R + YTC A + +GV + A +
Sbjct: 273 MPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQI 326
Score = 43.6 bits (98), Expect = 0.011
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 7/72 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W + ++L P D V +LT +Y C+A + +G
Sbjct: 260 GNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV 319
Query: 165 ASSSAELTVEDI 176
+ A++TV+ +
Sbjct: 320 IEAVAQITVKSL 331
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens cDNA
FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 83.8 bits (198), Expect = 9e-15
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 97 KPRFMENLQAVLTEEGLVS----FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
+P +E+ +L E LVS ECK G P PV++W+KD + L +T N G
Sbjct: 988 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNR-G 1044
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
I + A + + N E + AP V ++ P
Sbjct: 1045 QIIDIESAQISDAGIYKCVAI----NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPV 1100
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
R + P PSL W +D PV SS + + G L + + + D + CVA N
Sbjct: 1101 RLECEARGIPAPSLTWLKDGSPV--SSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 1158
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G+ L++ +P + +N+ ++S AV L C+ +P P L W KDG
Sbjct: 1159 AAGEKQRDIDLRVYVPPNIMGEE--QNVSVLISQ--AVELLCQSDAIPPPTLTWLKDGHP 1214
Query: 333 L--KPG----DIHRIISGQDGTC-SLGTYTCEASNCMG 363
L KPG + ++ +D G YTCEA+N G
Sbjct: 1215 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 1252
Score = 80.2 bits (189), Expect = 1e-13
Identities = 67/257 (26%), Positives = 111/257 (43%), Gaps = 16/257 (6%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTN 149
VP F + VL + V+ EC+V G P P + WFKDG+ L GD +L
Sbjct: 521 VPPTIIGTNFPNEVSVVLNRD--VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG 578
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
+ KN + TV + + ++ KL ++ K + + I+
Sbjct: 579 QV----LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSI-KGGNVTTDISVLIN 633
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKC 268
+ + P P++ WY+D QP+ SS+ ++ K + +L I + D A + C
Sbjct: 634 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQ----YLHIPRAQVSDSATYTC 689
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G + S + + +P + N Q +++ ++ LECK G P P+L W
Sbjct: 690 HVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAH--SLTLECKAAGNPSPILTWL 747
Query: 328 KDGEELKPGDIHRIISG 344
KDG +K D RI +G
Sbjct: 748 KDGVPVKANDNIRIEAG 764
Score = 73.3 bits (172), Expect = 1e-11
Identities = 66/262 (25%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L+ EC+ G P P ++W+KDGQ + Q + G Y I + Q S SA T
Sbjct: 635 LIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDK-GQYLHIPR---AQVSDSATYT 688
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV----EAKIDEPFRFTIKVAIPPEPSLLW 228
+ N EK P + G + + I K A P P L W
Sbjct: 689 CH-VANVAGTAEK-SFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 746
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
+D PV + + E G L+I + + +D+ ++ CVA + G+ + +++P
Sbjct: 747 LKDGVPVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVP 803
Query: 289 RHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI------- 341
+ E I+ + L+C V G P P + W KDG+ + D +I
Sbjct: 804 PAIEGGD--ETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLVDERDGFKILLNGRKL 861
Query: 342 ISGQDGTCSLGTYTCEASNCMG 363
+ Q + G Y C A+N G
Sbjct: 862 VIAQAQVSNTGLYRCMAANTAG 883
Score = 68.5 bits (160), Expect = 4e-10
Identities = 81/287 (28%), Positives = 118/287 (41%), Gaps = 47/287 (16%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ--LTG---------TNSLGSYC 155
++ L+ +C V G P P + W KDGQ + D ++ L G ++ G Y
Sbjct: 816 IVMVNNLLELDCHVTGSPPPTIMWLKDGQLVDERDGFKILLNGRKLVIAQAQVSNTGLYR 875
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A N G E+TV + S + + V K V +
Sbjct: 876 CMAANTAGDHKEEFEVTVHVPPT---------IKSSGLSERVVVKYKPVALQC------- 919
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
I IP PS+ W +DDQPV+ +++ +L + G L I D + CVA N G
Sbjct: 920 IANGIP-NPSITWLKDDQPVN-TAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAG 976
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSD----EGAVNLECKVIGVPQPVLKWYKDGE 331
+ T ++L H +P LE+ +L++ V LECK G P PV+ WYKD
Sbjct: 977 E--TQQHIQL----HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNR 1030
Query: 332 ELKPGD----IHR--IISGQDGTCS-LGTYTCEASNCMGVAASSASL 371
L ++R II + S G Y C A N G SL
Sbjct: 1031 LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSL 1077
Score = 65.7 bits (153), Expect = 2e-09
Identities = 62/294 (21%), Positives = 111/294 (37%), Gaps = 24/294 (8%)
Query: 85 HNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
+N VP + + N+ +L + L + C+V G P+P++ W+KD ++ Q
Sbjct: 422 YNLKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ 479
Query: 145 LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-- 202
+ G+ S A Q N + + P + G
Sbjct: 480 TVNNGRILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV--------PPTIIGTNFP 531
Query: 203 -SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFL 261
V ++ +V P P + W++D +P+ ++ +RG L ++
Sbjct: 532 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQV-LHLKNARRN 589
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
D+ ++C N G+ L + IP K ++ +++ + LEC+ G+P
Sbjct: 590 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINS--LIKLECETRGLPM 647
Query: 322 PVLKWYKDGEELKPGDIHRIIS-GQ------DGTCSLGTYTCEASNCMGVAASS 368
P + WYKDG+ + I GQ TYTC +N G A S
Sbjct: 648 PAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 701
Score = 64.9 bits (151), Expect = 4e-09
Identities = 75/295 (25%), Positives = 114/295 (38%), Gaps = 40/295 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP----------GDVYQLT 146
P Q + T EG+ V+ CK G P P + W K G+ + G +Y ++
Sbjct: 52 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 111
Query: 147 -GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G G Y C A N G A +LTV ++ L P + L E
Sbjct: 112 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEE 167
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
+ + ++PP P + W ++ Q + S H + I D
Sbjct: 168 VTLPCEVK-----SLPP-PIITWAKETQLISPFSPRHTFLPSGS---MKITETRTSDSGM 218
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ CVA N G + L + +P K R ++L+ + V++ C G P PV+
Sbjct: 219 YLCVAINIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQVGQR--VDIPCNAQGTPLPVIT 274
Query: 326 WYKDGEE-LKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
W K G L G+ H +S DGT S+ G YTC A+N G + +L
Sbjct: 275 WSKGGSTMLVDGEHH--VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 327
Score = 60.9 bits (141), Expect = 7e-08
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 35/270 (12%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT---GTNSL--------GSYCCIAKNCM 162
V C G P PV++W K G + + ++ GT S+ G Y C+A N
Sbjct: 259 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 318
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + E+T+ +Q E+ + P + E ++ F P
Sbjct: 319 G--TDETEITLH-VQEPPTVEDL-------EPP---YNTTFQERVANQRIEFPCPAKGTP 365
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P++ W + + + + E G + I ++ D E+ CVA N+ G +
Sbjct: 366 KPTIKWLHNGRELT-GREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAGTTERKYN 423
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRI 341
LK+ +P K + N+ +L+ NL C+V G P P++ WYKD ++ + I +
Sbjct: 424 LKVHVPPVIKDKEQVTNVSVLLNQ--LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 481
Query: 342 ISG------QDGTCSLGTYTCEASNCMGVA 365
+G + G Y+C+A N G +
Sbjct: 482 NNGRILKLFRATPEDAGRYSCKAINIAGTS 511
Score = 49.6 bits (113), Expect = 2e-04
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 35/233 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP----------GDV-YQLTGTNSLGSYCCIAKNCM 162
V+ C+V P P+++W K+ Q + P G + T T+ G Y C+A N
Sbjct: 168 VTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAINIA 227
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + +L V + PK G K ++ ++ + P
Sbjct: 228 GNVTQAVKLNV------------------HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTP 269
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W + + H+ + G +D QA D + CVA N G T
Sbjct: 270 LPVITWSKGGSTMLVDGEHHVSNPD-GTLSID-QATPS-DAGIYTCVATNIAGTDETEIT 326
Query: 283 LKLIIPRHYK--KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
L + P + +P + Q ++++ + C G P+P +KW +G EL
Sbjct: 327 LHVQEPPTVEDLEPPYNTTFQERVANQ-RIEFPCPAKGTPKPTIKWLHNGREL 378
>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
Length = 1502
Score = 83.4 bits (197), Expect = 1e-14
Identities = 71/284 (25%), Positives = 124/284 (43%), Gaps = 12/284 (4%)
Query: 98 PRFMENLQAVLTEEGLV-SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
PRF++ + + G V SF C+ G P P ++W K G+++ + S G+
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK-FVHGLKSVEAKIDEPFRFT 215
I + + E ++ ++ KL + ++Q P F + + K+ E R
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152
Query: 216 IKVAIP---PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
+ P+P + W++D PVD S+ K+ R L I++ E DQ +++CVA N
Sbjct: 153 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGA-LQIESSEETDQGKYECVATN 211
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE 331
G +S L + PRF + + + G VN+ C +G P P +KW + E
Sbjct: 212 SAGVRYSSP-ANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAE 270
Query: 332 ELKPGDI----HRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
+L P D ++ D S + C A + +GV + A +
Sbjct: 271 DLTPEDDMPVGRNVLELTDVKDSANYHPCVAMSSLGVIEAVAQI 314
Score = 43.6 bits (98), Expect = 0.011
Identities = 46/195 (23%), Positives = 74/195 (37%), Gaps = 17/195 (8%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+F+ K F + P+P + W + + V+ + +E
Sbjct: 31 EPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 90
Query: 253 LDIQALEF-LDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQA-----ILSD 306
L IQ L D+ ++CVA N G+ KL + R + P N+ ++
Sbjct: 91 LRIQPLRTPRDENVYECVAQNSVGEITVHA--KLTVLREDQLPSGFPNIDMGPQLKVVER 148
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKP----GDIHRIISG-----QDGTCSLGTYTCE 357
+ C G P P + W+KD + P G I ++ SG G Y C
Sbjct: 149 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECV 208
Query: 358 ASNCMGVAASSASLL 372
A+N GV SS + L
Sbjct: 209 ATNSAGVRYSSPANL 223
>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
Length = 1911
Score = 83.4 bits (197), Expect = 1e-14
Identities = 71/284 (25%), Positives = 124/284 (43%), Gaps = 12/284 (4%)
Query: 98 PRFMENLQAVLTEEGLV-SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
PRF++ + + G V SF C+ G P P ++W K G+++ + S G+
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK-FVHGLKSVEAKIDEPFRFT 215
I + + E ++ ++ KL + ++Q P F + + K+ E R
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152
Query: 216 IKVAIP---PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
+ P+P + W++D PVD S+ K+ R L I++ E DQ +++CVA N
Sbjct: 153 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGA-LQIESSEETDQGKYECVATN 211
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE 331
G +S L + PRF + + + G VN+ C +G P P +KW + E
Sbjct: 212 SAGVRYSSP-ANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAE 270
Query: 332 ELKPGDI----HRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
+L P D ++ D S + C A + +GV + A +
Sbjct: 271 DLTPEDDMPVGRNVLELTDVKDSANYHPCVAMSSLGVIEAVAQI 314
Score = 43.6 bits (98), Expect = 0.011
Identities = 46/195 (23%), Positives = 74/195 (37%), Gaps = 17/195 (8%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+F+ K F + P+P + W + + V+ + +E
Sbjct: 31 EPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 90
Query: 253 LDIQALEF-LDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQA-----ILSD 306
L IQ L D+ ++CVA N G+ KL + R + P N+ ++
Sbjct: 91 LRIQPLRTPRDENVYECVAQNSVGEITVHA--KLTVLREDQLPSGFPNIDMGPQLKVVER 148
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKP----GDIHRIISG-----QDGTCSLGTYTCE 357
+ C G P P + W+KD + P G I ++ SG G Y C
Sbjct: 149 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECV 208
Query: 358 ASNCMGVAASSASLL 372
A+N GV SS + L
Sbjct: 209 ATNSAGVRYSSPANL 223
>BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 81.8 bits (193), Expect = 4e-14
Identities = 67/270 (24%), Positives = 115/270 (42%), Gaps = 11/270 (4%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W++D PVD S+ K+ R + L I+ E DQ +++CVA N G S L
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRY-SAPANL 217
Query: 286 IIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD---IHRI 341
+ PRF + + G+VN+ C +G P P +KW E+L P D I R
Sbjct: 218 YVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRN 277
Query: 342 ISGQDGTCSLGTYTCEASNCMGVAASSASL 371
+ + YTC A + +GV + A +
Sbjct: 278 VLELNDVRQSANYTCVAMSTLGVIEAIAQI 307
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 241 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 300
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 301 IEAIAQITVK 310
>BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.
Length = 1496
Score = 80.2 bits (189), Expect = 1e-13
Identities = 65/273 (23%), Positives = 118/273 (43%), Gaps = 13/273 (4%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAFNDFG---QSVTSCF 282
W++D PVD S+ K+ R + L I+ E DQ +++CVA N G + + +
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLY 218
Query: 283 LKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD---I 338
++ + PRF + + G+VN+ C +G P P +KW E+L P D I
Sbjct: 219 VRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI 278
Query: 339 HRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
R + + YTC A + +GV + A +
Sbjct: 279 GRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 311
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 245 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 304
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 305 IEAIAQITVK 314
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 80.2 bits (189), Expect = 1e-13
Identities = 94/349 (26%), Positives = 146/349 (41%), Gaps = 67/349 (19%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT- 146
P++ + P F+ LQ ++G VSF+C V G P P + WFKDG+ L+ D Y +
Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176
Query: 147 ---GTNSL----------GSYCCIAKNCMGQASSSAELTVE----DIQNQLNEEEKLQLF 189
G + L G Y C+A+N MG +S+ AEL V+ D + E F
Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236
Query: 190 S------------------KNQAPKFVHGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWYR 230
S + Q P+ V L+ ++ A +F +KV P P L W++
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH 290
D QP+ S+ + +++ + L+I ++ D ++ N G + +S L + P
Sbjct: 5297 DGQPLTASAHIRM-TDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355
Query: 291 YKK------------PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL---- 333
++ PR LE +G ++ KV G P P + W ++ E
Sbjct: 5356 PEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLW 5415
Query: 334 ----KPG-------DIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
PG H ++ G GTYTC ASN G A SASL
Sbjct: 5416 IGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASL 5464
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 17/189 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F L A++ E + +V P+P + WY+D + V L ++ G L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLE 313
+ +L +D ++ C A + G T + + +P PRF+ ++A EG
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 6128
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC----------SLGTYTCEASNCM 362
C + G P P ++WYKDG L G+ + +S + G LG Y CE N +
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188
Query: 363 GVAASSASL 371
G A +SA L
Sbjct: 6189 GSARASAEL 6197
Score = 65.7 bits (153), Expect = 2e-09
Identities = 51/193 (26%), Positives = 87/193 (45%), Gaps = 15/193 (7%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFL 253
AP+F+ K+ + + + ++ P P + W +D QPV +R L ++ ++ L
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA-QDGDLYRL 67
Query: 254 DIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR--HYKKPRFLENLQAILSDEGA-V 310
I L D ++ C A N G++ + L++ + P FL +I EG+
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEA 127
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-----------GTYTCEAS 359
C+V G P+P + W KDG L D R+ + G S GTY A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 360 NCMGVAASSASLL 372
N +G A+++A+L+
Sbjct: 188 NPLGAASAAAALV 200
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
+R P F E L E G V C+V G P PV+SW+KDG+ ++ D + + + GS
Sbjct: 6011 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGS 6069
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
I + G S + K+ + P+FV+ +++ E +
Sbjct: 6070 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV---QVPPRFVNKVRASPFVEGEDAQ 6126
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER-GVFFLDIQALEFLDQAEWKCVAFN 272
FT + P P + WY+D + ++ E R G+ L I+A D ++C N
Sbjct: 6127 FTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 6186
Query: 273 DFGQSVTSCFLKLIIP 288
G + S L++ P
Sbjct: 6187 RLGSARASAELRIQSP 6202
Score = 59.3 bits (137), Expect = 2e-07
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 26/201 (12%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLT- 146
PRF+ +A + G + C++VG PTP +SW KD Q + + GD+Y+LT
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 147 ---GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G Y C A+N +G+A ++ L V+ + QAP F+ S
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVD-----------AEAACAEQAPHFLLRPTS 118
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLD 262
+ + F +V P P++ W +D + + E + EE G L I+A D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 263 QAEWKCVAFNDFGQSVTSCFL 283
++ A N G + + L
Sbjct: 179 GGTYEVRAENPLGAASAAAAL 199
Score = 56.8 bits (131), Expect = 1e-06
Identities = 78/288 (27%), Positives = 129/288 (44%), Gaps = 38/288 (13%)
Query: 88 HPTVPKN-YRKPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N +QA ++S C+V T V +W+KDG++L
Sbjct: 1066 HITEPKMMFAKEQSVHNEVQAEAGASAMLS--CEVAQAQTEV-TWYKDGKKLSSSSK--- 1119
Query: 146 TGTNSLGSYCCIAKNCMGQASS---SAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G G + G+A + S E + + L+ E +F+K Q+ VH
Sbjct: 1120 VGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQS---VHN-- 1174
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFL 261
V+A+ + +VA P+ + WY+D + + SS+ + E +G L +Q +
Sbjct: 1175 EVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRM--EVKGCTRRLVVQQVGKA 1231
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YKKPRFLENLQAILSDEGA-VNLECKVIGV 319
D E+ C A GQ V S L + P+ + K + + N + ++ GA L C+V
Sbjct: 1232 DAGEYSCEAG---GQRV-SFQLHITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQA 1285
Query: 320 PQPVLKWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
Q + WYKDG++L G + +++ Q G G YTCEA
Sbjct: 1286 -QTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 54.8 bits (126), Expect = 5e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
++ P F E L ++ G V L C+V G P+PV+ WYKDG+ ++ H +I DG+C
Sbjct: 6011 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 6070
Query: 350 SL----------GTYTCEASNCMGVAASSASLL 372
+L G Y C A++ G ++ +L
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKIL 6103
Score = 53.2 bits (122), Expect = 1e-05
Identities = 67/271 (24%), Positives = 116/271 (42%), Gaps = 43/271 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGD-----VYQLTGTNSL 151
P F+ ++ EG +F C+V G P P +SW KDG+ L D V +L ++L
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASAL 169
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVED----------------IQNQLNEEEK 185
G+Y A+N +G AS++A L V+ + + E
Sbjct: 170 RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229
Query: 186 LQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGK 245
++ +P G ++ + R + V P+P +W +D Q V E R + +
Sbjct: 230 MRAEGAPASPPST-GTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYE 288
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI-L 304
+ + F L I + D+ + C A N GQ+ +S L++ R P F + LQ + +
Sbjct: 289 DAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV---LVVVREPAVP-FKKRLQDLEV 344
Query: 305 SDEGAVNLECKVIGVPQPVLK--WYKDGEEL 333
++ + C+ VPQP + W+K+ L
Sbjct: 345 REKESATFLCE---VPQPSTEAAWFKEETRL 372
Score = 51.2 bits (117), Expect = 6e-05
Identities = 61/255 (23%), Positives = 105/255 (41%), Gaps = 26/255 (10%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ C+V T V+ W+KDG++L + S E +
Sbjct: 1001 TLSCEVAQAQTEVM-WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ +L+ E +F+K Q+ VH V+A+ + +VA + + WY+D +
Sbjct: 1060 RVSFRLHITEPKMMFAKEQS---VHN--EVQAEAGASAMLSCEVA-QAQTEVTWYKDGKK 1113
Query: 235 VDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YK 292
+ SS+ +G E +G L + D E+ C A GQ V S L + P+ +
Sbjct: 1114 LSSSSK--VGMEVKGCTRRLVLPQAGKADAGEYSCEAG---GQRV-SFHLHITEPKGVFA 1167
Query: 293 KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELK---------PGDIHRIIS 343
K + + N + ++ G + + PQ + WYKDG++L G R++
Sbjct: 1168 KEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVV 1225
Query: 344 GQDGTCSLGTYTCEA 358
Q G G Y+CEA
Sbjct: 1226 QQVGKADAGEYSCEA 1240
Score = 50.0 bits (114), Expect = 1e-04
Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 35/277 (12%)
Query: 96 RKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSY 154
R RF E L+ + + E G + C + PV W L+PGD Y L ++
Sbjct: 3183 RPVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGDKYSLRQEGAMLEL 3241
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ +N Q S + D + L +F+ L++ EA E
Sbjct: 3242 --VVRNLRPQDSGRYSCSFGD------QTTSATLTVTALPAQFIGKLRNKEAT--EGATA 3291
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
T++ + + W + + + + R L +++ + L I+ L +D AE+ CV
Sbjct: 3292 TLRCELSKAAPVEWRKGSETLRDGDRYCL-RQDGAMCELQIRGLAMVDAAEYSCVC---- 3346
Query: 275 GQSVTSCFLKL-IIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEE 332
G+ TS L + +P H F+ L+ S EGA L C+ + PV +W K E
Sbjct: 3347 GEERTSASLTIRPMPAH-----FIGRLRHQESIEGATATLRCE-LSKAAPV-EWRKGRES 3399
Query: 333 LKPGDIHRIISGQDGTCSLGTYTCEASNCMGVAASSA 369
L+ GD H + QDG CE C G+A + A
Sbjct: 3400 LRDGDRHSL--RQDGA------VCELQIC-GLAVADA 3427
Score = 48.4 bits (110), Expect = 4e-04
Identities = 67/283 (23%), Positives = 108/283 (38%), Gaps = 28/283 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT 146
H T PK + K + + N V E G + V P ++W+KDG++L ++
Sbjct: 1158 HITEPKGVFAKEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRME 1215
Query: 147 GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
S E + + QL+ E +F+K Q VH EA
Sbjct: 1216 VKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQ---LVHNEVRTEA 1272
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAE 265
+ A + + WY+D + + SS+ + E G L +Q D E
Sbjct: 1273 GASATLSCEVAQA---QTEVTWYKDGKKLSSSSKVRI--EAAGCMRQLVVQQAGQADAGE 1327
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVL 324
+ C A G S L + P+ L + + + ++ GA+ L C+V Q +
Sbjct: 1328 YTCEA----GGQRLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQA-QTEV 1381
Query: 325 KWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
WYKDG++L G R++ Q G Y+CEA
Sbjct: 1382 TWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Score = 48.0 bits (109), Expect = 5e-04
Identities = 66/285 (23%), Positives = 111/285 (38%), Gaps = 28/285 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N V TE G + C+V T V +W+KDG++L ++
Sbjct: 1250 HITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQAQTEV-TWYKDGKKLSSSSKVRI 1306
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
+ + E + + L+ E +F+K Q H + V+
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQ---LAH--RKVQ 1361
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQA 264
A+ + +VA + + WY+D + + SS+ + E G L +Q D
Sbjct: 1362 AEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRM--EAVGCTRRLVVQQACQADTG 1418
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVL 324
E+ C A G S L + P+ + + + L C+V V+
Sbjct: 1419 EYSCEA----GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVM 1474
Query: 325 KWYKDGEELK---------PGDIHRIISGQDGTCSLGTYTCEASN 360
WYKDG++L G R++ Q G G Y+CEA +
Sbjct: 1475 -WYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGS 1518
Score = 46.4 bits (105), Expect = 0.002
Identities = 29/74 (39%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEA 358
A+ LEC V +W KDG EL G H I DGTCSL G YTC+
Sbjct: 4914 ALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQV 4973
Query: 359 SNCMGVAASSASLL 372
SN G SA ++
Sbjct: 4974 SNKFGQVTHSACVV 4987
Score = 45.6 bits (103), Expect = 0.003
Identities = 60/257 (23%), Positives = 103/257 (40%), Gaps = 30/257 (11%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASS---SAEL 171
+ C+V T V+ W+KDG++L ++ ++G + GQA + S E
Sbjct: 1461 TLSCEVAQAQTEVM-WYKDGKKLSFSSKVRM---EAVGCTRRLVVQQAGQAVAGEYSCEA 1516
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD 231
+ + L+ E +F+K Q + V+A+ + +VA + + WY+D
Sbjct: 1517 GSQRLSFHLHVAEPKAVFAKEQPAS-----REVQAEAGTSATLSCEVA-QAQTEVTWYKD 1570
Query: 232 DQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH 290
+ + SS+ + E G L +Q D E+ C A G S L + P+
Sbjct: 1571 GKKLSSSSKVRM--EAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVAEPKV 1624
Query: 291 YKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP---------GDIHRI 341
+ + + L C+V Q + WYKDG++L G R+
Sbjct: 1625 VFAKEQPAHREVQAEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRVEAVGCTRRL 1683
Query: 342 ISGQDGTCSLGTYTCEA 358
+ Q G G Y+CEA
Sbjct: 1684 VVQQAGQAEAGEYSCEA 1700
Score = 44.0 bits (99), Expect = 0.009
Identities = 55/245 (22%), Positives = 96/245 (39%), Gaps = 22/245 (8%)
Query: 96 RKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSY 154
R+ +E+L+ V +EG +F C++ + WF D L ++ ++ G Y
Sbjct: 3003 RRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQP--GGY 3060
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ + S I + ++ + P V + +A I E
Sbjct: 3061 HVLTLRQLALKDSGT------IYFEAGDQRASAALRVTEKPS-VFSRELTDATITEGEDL 3113
Query: 215 TIKVAIPP-EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T+ + + W +D + + S+RC L E L I D +KC A
Sbjct: 3114 TLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLL-ITGATLQDSGRYKCEA--- 3169
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G + +S +++ H + RF E L+ + + + GA L C + V PV KW
Sbjct: 3170 -GGACSSSIVRV----HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNV 3223
Query: 333 LKPGD 337
L+PGD
Sbjct: 3224 LRPGD 3228
Score = 42.7 bits (96), Expect = 0.020
Identities = 44/178 (24%), Positives = 82/178 (46%), Gaps = 13/178 (7%)
Query: 181 NEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP-PEPSLLWYRDDQPVDESS 239
+++ + +L + + + V GL++VEA+ E T++V + + W RD +
Sbjct: 2063 DDKTQAKLTVEMRQVRLVRGLQAVEAR--EQGTATMEVQLSHADVDGSWTRDGLRFQQGP 2120
Query: 240 RCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN 299
CHL RG + L L + + F G ++ + +P + +P L++
Sbjct: 2121 TCHLAV--RGP--MHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRP--LQD 2174
Query: 300 LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCE 357
+ + +++ V LEC+ + P ++W KDG EL+ G I+ Q SL Y CE
Sbjct: 2175 V--VTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKT-MAIAAQGACRSLTIYRCE 2228
Score = 41.5 bits (93), Expect = 0.046
Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 20/241 (8%)
Query: 101 MENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAK 159
+E LQ V EG SF+C++ W G L+ ++ +T + K
Sbjct: 4253 LEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHK 4312
Query: 160 NCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVA 219
+ A TV + E +L++ +KN V GL++VEA F +++
Sbjct: 4313 VTLEDAG-----TVSFHVGTCSSEAQLKVTAKNTV---VRGLENVEALEGGEALFECQLS 4364
Query: 220 IPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P + W DD+PV S + E G+ L ++ L D +A G V
Sbjct: 4365 QPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLA----GDMV 4420
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVI-GVPQPVLKWYKDGEELKPG 336
TS FL + R ++ LE L+ GA C + VP WY +G ++P
Sbjct: 4421 TSAFLTV---RGWRL-EILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPD 4476
Query: 337 D 337
D
Sbjct: 4477 D 4477
Score = 39.9 bits (89), Expect = 0.14
Identities = 63/255 (24%), Positives = 103/255 (40%), Gaps = 26/255 (10%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
+F E L+ EG + + PV W K + L+ GD Y L G+ C +
Sbjct: 3451 KFTEGLRNEEAVEGATAMLWCELSKVAPV-EWRKGPENLRDGDRYIL---RQEGTRCELQ 3506
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ A + L V E L + +F+ +K+ EA+ E ++
Sbjct: 3507 ICGLAMADAGEYLCVCG-----QERTSATLTIRALPARFIEDVKNQEAR--EGATAVLQC 3559
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
+ + W + + + + R L +++ L I+ L D E+ CV GQ
Sbjct: 3560 ELNSAAPVEWRKGSETLRDGDRYSL-RQDGTKCELQIRGLAMADTGEYSCVC----GQER 3614
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGD 337
TS L + +F E L+ + EGA L C++ + PV +W+K E L+ GD
Sbjct: 3615 TSAMLTV----RALPIKFTEGLRNEEATEGATAVLRCELSKMA-PV-EWWKGHETLRDGD 3668
Query: 338 IHRIISGQDGT-CSL 351
H + QDG C L
Sbjct: 3669 RHSL--RQDGARCEL 3681
Score = 39.1 bits (87), Expect = 0.25
Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 24/238 (10%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
+F+E L+ EG + + PV W K + L+ GD + L S
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSKAAPV-EWRKGHETLRDGDRHSLRQDGS-------- 3765
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP-KFVHGLKSVEAKIDEPFRFTIK 217
C Q A + + +E + P +F+ +K+ EA+ E ++
Sbjct: 3766 -RCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAR--EGATAVLQ 3822
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+ + W + + + R L +++ L I L D E+ CV GQ
Sbjct: 3823 CELSKAAPVEWRKGSETLRGGDRYSL-RQDGTRCELQIHGLSVADTGEYSCVC----GQE 3877
Query: 278 VTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELK 334
TS L + P+ P F E LQ++ ++EG+ L+C+ + P + W K G +L+
Sbjct: 3878 RTSATLTVRAPQ----PVFREPLQSLQAEEGSTATLQCE-LSEPTATVVWSKGGLQLQ 3930
Score = 38.7 bits (86), Expect = 0.33
Identities = 61/290 (21%), Positives = 105/290 (36%), Gaps = 28/290 (9%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP 139
SI+M + P + N + A L EE + E + ++W KDG+ L P
Sbjct: 692 SIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAE---LSDQAAAVTWLKDGRTLSP 748
Query: 140 GDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED--IQNQLNEEEKLQLFSKNQAPKF 197
G Y++ S G + ++ + E I QL+ + + K+ A
Sbjct: 749 GPKYEVQA--SAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAG-- 804
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
V+A P +F + + + WY+D + S L ++ L
Sbjct: 805 ----SCVDAVAGGPAQFECETS-EAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAAT 859
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVI 317
+ D+ + C G+ L++ P+ L + + L C+V
Sbjct: 860 VTRQDEGTYSC----RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEV- 914
Query: 318 GVPQPVLKWYKDGEELK---------PGDIHRIISGQDGTCSLGTYTCEA 358
Q + WYKDG++L G R++ Q G G Y+CEA
Sbjct: 915 AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Score = 37.9 bits (84), Expect = 0.57
Identities = 51/245 (20%), Positives = 95/245 (38%), Gaps = 20/245 (8%)
Query: 128 LSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQ 187
++W KDG E++ ++ + + A S + E + EE
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEV-- 1807
Query: 188 LFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEE 247
A KF L+ V ++ +++ P ++W + + R + E
Sbjct: 1808 ------AAKFCRLLEPVCGELGGTVTLACELS-PACAEVVWRCGNTQLRVGKRFQM-VAE 1859
Query: 248 RGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDE 307
V L + L D E+ C + +D TS L + +PR K F+ L ++++E
Sbjct: 1860 GPVRSLTVLGLRAEDAGEYVCESRDDH----TSAQLTVSVPRVVK---FMSGLSTVVAEE 1912
Query: 308 GA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRII-SGQDGTCSLGTYTCEASNCMGVA 365
G +C V+ + W++DG L+P + I SG + ++ E + + V
Sbjct: 1913 GGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVE 1971
Query: 366 ASSAS 370
A AS
Sbjct: 1972 AEGAS 1976
Score = 37.1 bits (82), Expect = 1.00
Identities = 21/86 (24%), Positives = 34/86 (39%)
Query: 191 KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV 250
+ + P F H EA++ + R VA + W +D + + H+ + G
Sbjct: 4894 QQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGT 4953
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQ 276
L I L+ D + C N FGQ
Sbjct: 4954 CSLLITGLDRADAGCYTCQVSNKFGQ 4979
Score = 34.7 bits (76), Expect = 5.3
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 10/67 (14%)
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNC 361
L C V G P+P W KDG+ + G H + L G YTC ASN
Sbjct: 257 LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316
Query: 362 MGVAASS 368
+G SS
Sbjct: 317 VGQTYSS 323
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 80.2 bits (189), Expect = 1e-13
Identities = 94/349 (26%), Positives = 146/349 (41%), Gaps = 67/349 (19%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT- 146
P++ + P F+ LQ ++G VSF+C V G P P + WFKDG+ L+ D Y +
Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176
Query: 147 ---GTNSL----------GSYCCIAKNCMGQASSSAELTVE----DIQNQLNEEEKLQLF 189
G + L G Y C+A+N MG +S+ AEL V+ D + E F
Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236
Query: 190 S------------------KNQAPKFVHGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWYR 230
S + Q P+ V L+ ++ A +F +KV P P L W++
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH 290
D QP+ S+ + +++ + L+I ++ D ++ N G + +S L + P
Sbjct: 5297 DGQPLTASAHIRM-TDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355
Query: 291 YKK------------PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL---- 333
++ PR LE +G ++ KV G P P + W ++ E
Sbjct: 5356 PEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLW 5415
Query: 334 ----KPG-------DIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
PG H ++ G GTYTC ASN G A SASL
Sbjct: 5416 IGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASL 5464
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 17/189 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F L A++ E + +V P+P + WY+D + V L ++ G L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLE 313
+ +L +D ++ C A + G T + + +P PRF+ ++A EG
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 6128
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC----------SLGTYTCEASNCM 362
C + G P P ++WYKDG L G+ + +S + G LG Y CE N +
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188
Query: 363 GVAASSASL 371
G A +SA L
Sbjct: 6189 GSARASAEL 6197
Score = 65.7 bits (153), Expect = 2e-09
Identities = 51/193 (26%), Positives = 87/193 (45%), Gaps = 15/193 (7%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFL 253
AP+F+ K+ + + + ++ P P + W +D QPV +R L ++ ++ L
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA-QDGDLYRL 67
Query: 254 DIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR--HYKKPRFLENLQAILSDEGA-V 310
I L D ++ C A N G++ + L++ + P FL +I EG+
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEA 127
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-----------GTYTCEAS 359
C+V G P+P + W KDG L D R+ + G S GTY A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 360 NCMGVAASSASLL 372
N +G A+++A+L+
Sbjct: 188 NPLGAASAAAALV 200
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
+R P F E L E G V C+V G P PV+SW+KDG+ ++ D + + + GS
Sbjct: 6011 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGS 6069
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
I + G S + K+ + P+FV+ +++ E +
Sbjct: 6070 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV---QVPPRFVNKVRASPFVEGEDAQ 6126
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER-GVFFLDIQALEFLDQAEWKCVAFN 272
FT + P P + WY+D + ++ E R G+ L I+A D ++C N
Sbjct: 6127 FTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 6186
Query: 273 DFGQSVTSCFLKLIIP 288
G + S L++ P
Sbjct: 6187 RLGSARASAELRIQSP 6202
Score = 59.3 bits (137), Expect = 2e-07
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 26/201 (12%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLT- 146
PRF+ +A + G + C++VG PTP +SW KD Q + + GD+Y+LT
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 147 ---GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G Y C A+N +G+A ++ L V+ + QAP F+ S
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVD-----------AEAACAEQAPHFLLRPTS 118
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLD 262
+ + F +V P P++ W +D + + E + EE G L I+A D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 263 QAEWKCVAFNDFGQSVTSCFL 283
++ A N G + + L
Sbjct: 179 GGTYEVRAENPLGAASAAAAL 199
Score = 56.8 bits (131), Expect = 1e-06
Identities = 78/288 (27%), Positives = 129/288 (44%), Gaps = 38/288 (13%)
Query: 88 HPTVPKN-YRKPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N +QA ++S C+V T V +W+KDG++L
Sbjct: 1066 HITEPKMMFAKEQSVHNEVQAEAGASAMLS--CEVAQAQTEV-TWYKDGKKLSSSSK--- 1119
Query: 146 TGTNSLGSYCCIAKNCMGQASS---SAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G G + G+A + S E + + L+ E +F+K Q+ VH
Sbjct: 1120 VGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQS---VHN-- 1174
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFL 261
V+A+ + +VA P+ + WY+D + + SS+ + E +G L +Q +
Sbjct: 1175 EVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRM--EVKGCTRRLVVQQVGKA 1231
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YKKPRFLENLQAILSDEGA-VNLECKVIGV 319
D E+ C A GQ V S L + P+ + K + + N + ++ GA L C+V
Sbjct: 1232 DAGEYSCEAG---GQRV-SFQLHITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQA 1285
Query: 320 PQPVLKWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
Q + WYKDG++L G + +++ Q G G YTCEA
Sbjct: 1286 -QTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 54.8 bits (126), Expect = 5e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
++ P F E L ++ G V L C+V G P+PV+ WYKDG+ ++ H +I DG+C
Sbjct: 6011 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 6070
Query: 350 SL----------GTYTCEASNCMGVAASSASLL 372
+L G Y C A++ G ++ +L
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKIL 6103
Score = 53.2 bits (122), Expect = 1e-05
Identities = 67/271 (24%), Positives = 116/271 (42%), Gaps = 43/271 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGD-----VYQLTGTNSL 151
P F+ ++ EG +F C+V G P P +SW KDG+ L D V +L ++L
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASAL 169
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVED----------------IQNQLNEEEK 185
G+Y A+N +G AS++A L V+ + + E
Sbjct: 170 RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229
Query: 186 LQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGK 245
++ +P G ++ + R + V P+P +W +D Q V E R + +
Sbjct: 230 MRAEGAPASPPST-GTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYE 288
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI-L 304
+ + F L I + D+ + C A N GQ+ +S L++ R P F + LQ + +
Sbjct: 289 DAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV---LVVVREPAVP-FKKRLQDLEV 344
Query: 305 SDEGAVNLECKVIGVPQPVLK--WYKDGEEL 333
++ + C+ VPQP + W+K+ L
Sbjct: 345 REKESATFLCE---VPQPSTEAAWFKEETRL 372
Score = 51.2 bits (117), Expect = 6e-05
Identities = 61/255 (23%), Positives = 105/255 (41%), Gaps = 26/255 (10%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ C+V T V+ W+KDG++L + S E +
Sbjct: 1001 TLSCEVAQAQTEVM-WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ +L+ E +F+K Q+ VH V+A+ + +VA + + WY+D +
Sbjct: 1060 RVSFRLHITEPKMMFAKEQS---VHN--EVQAEAGASAMLSCEVA-QAQTEVTWYKDGKK 1113
Query: 235 VDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YK 292
+ SS+ +G E +G L + D E+ C A GQ V S L + P+ +
Sbjct: 1114 LSSSSK--VGMEVKGCTRRLVLPQAGKADAGEYSCEAG---GQRV-SFHLHITEPKGVFA 1167
Query: 293 KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELK---------PGDIHRIIS 343
K + + N + ++ G + + PQ + WYKDG++L G R++
Sbjct: 1168 KEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVV 1225
Query: 344 GQDGTCSLGTYTCEA 358
Q G G Y+CEA
Sbjct: 1226 QQVGKADAGEYSCEA 1240
Score = 50.0 bits (114), Expect = 1e-04
Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 35/277 (12%)
Query: 96 RKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSY 154
R RF E L+ + + E G + C + PV W L+PGD Y L ++
Sbjct: 3183 RPVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGDKYSLRQEGAMLEL 3241
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ +N Q S + D + L +F+ L++ EA E
Sbjct: 3242 --VVRNLRPQDSGRYSCSFGD------QTTSATLTVTALPAQFIGKLRNKEAT--EGATA 3291
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
T++ + + W + + + + R L +++ + L I+ L +D AE+ CV
Sbjct: 3292 TLRCELSKAAPVEWRKGSETLRDGDRYCL-RQDGAMCELQIRGLAMVDAAEYSCVC---- 3346
Query: 275 GQSVTSCFLKL-IIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEE 332
G+ TS L + +P H F+ L+ S EGA L C+ + PV +W K E
Sbjct: 3347 GEERTSASLTIRPMPAH-----FIGRLRHQESIEGATATLRCE-LSKAAPV-EWRKGRES 3399
Query: 333 LKPGDIHRIISGQDGTCSLGTYTCEASNCMGVAASSA 369
L+ GD H + QDG CE C G+A + A
Sbjct: 3400 LRDGDRHSL--RQDGA------VCELQIC-GLAVADA 3427
Score = 48.4 bits (110), Expect = 4e-04
Identities = 67/283 (23%), Positives = 108/283 (38%), Gaps = 28/283 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT 146
H T PK + K + + N V E G + V P ++W+KDG++L ++
Sbjct: 1158 HITEPKGVFAKEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRME 1215
Query: 147 GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
S E + + QL+ E +F+K Q VH EA
Sbjct: 1216 VKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQ---LVHNEVRTEA 1272
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAE 265
+ A + + WY+D + + SS+ + E G L +Q D E
Sbjct: 1273 GASATLSCEVAQA---QTEVTWYKDGKKLSSSSKVRI--EAAGCMRQLVVQQAGQADAGE 1327
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVL 324
+ C A G S L + P+ L + + + ++ GA+ L C+V Q +
Sbjct: 1328 YTCEA----GGQRLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQA-QTEV 1381
Query: 325 KWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
WYKDG++L G R++ Q G Y+CEA
Sbjct: 1382 TWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Score = 48.0 bits (109), Expect = 5e-04
Identities = 66/285 (23%), Positives = 111/285 (38%), Gaps = 28/285 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N V TE G + C+V T V +W+KDG++L ++
Sbjct: 1250 HITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQAQTEV-TWYKDGKKLSSSSKVRI 1306
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
+ + E + + L+ E +F+K Q H + V+
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQ---LAH--RKVQ 1361
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQA 264
A+ + +VA + + WY+D + + SS+ + E G L +Q D
Sbjct: 1362 AEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRM--EAVGCTRRLVVQQACQADTG 1418
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVL 324
E+ C A G S L + P+ + + + L C+V V+
Sbjct: 1419 EYSCEA----GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVM 1474
Query: 325 KWYKDGEELK---------PGDIHRIISGQDGTCSLGTYTCEASN 360
WYKDG++L G R++ Q G G Y+CEA +
Sbjct: 1475 -WYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGS 1518
Score = 46.4 bits (105), Expect = 0.002
Identities = 29/74 (39%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEA 358
A+ LEC V +W KDG EL G H I DGTCSL G YTC+
Sbjct: 4914 ALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQV 4973
Query: 359 SNCMGVAASSASLL 372
SN G SA ++
Sbjct: 4974 SNKFGQVTHSACVV 4987
Score = 45.6 bits (103), Expect = 0.003
Identities = 60/257 (23%), Positives = 103/257 (40%), Gaps = 30/257 (11%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASS---SAEL 171
+ C+V T V+ W+KDG++L ++ ++G + GQA + S E
Sbjct: 1461 TLSCEVAQAQTEVM-WYKDGKKLSFSSKVRM---EAVGCTRRLVVQQAGQAVAGEYSCEA 1516
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD 231
+ + L+ E +F+K Q + V+A+ + +VA + + WY+D
Sbjct: 1517 GSQRLSFHLHVAEPKAVFAKEQPAS-----REVQAEAGTSATLSCEVA-QAQTEVTWYKD 1570
Query: 232 DQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH 290
+ + SS+ + E G L +Q D E+ C A G S L + P+
Sbjct: 1571 GKKLSSSSKVRM--EAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVAEPKV 1624
Query: 291 YKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP---------GDIHRI 341
+ + + L C+V Q + WYKDG++L G R+
Sbjct: 1625 VFAKEQPAHREVQAEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRVEAVGCTRRL 1683
Query: 342 ISGQDGTCSLGTYTCEA 358
+ Q G G Y+CEA
Sbjct: 1684 VVQQAGQAEAGEYSCEA 1700
Score = 44.0 bits (99), Expect = 0.009
Identities = 55/245 (22%), Positives = 96/245 (39%), Gaps = 22/245 (8%)
Query: 96 RKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSY 154
R+ +E+L+ V +EG +F C++ + WF D L ++ ++ G Y
Sbjct: 3003 RRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQP--GGY 3060
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ + S I + ++ + P V + +A I E
Sbjct: 3061 HVLTLRQLALKDSGT------IYFEAGDQRASAALRVTEKPS-VFSRELTDATITEGEDL 3113
Query: 215 TIKVAIPP-EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T+ + + W +D + + S+RC L E L I D +KC A
Sbjct: 3114 TLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLL-ITGATLQDSGRYKCEA--- 3169
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G + +S +++ H + RF E L+ + + + GA L C + V PV KW
Sbjct: 3170 -GGACSSSIVRV----HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNV 3223
Query: 333 LKPGD 337
L+PGD
Sbjct: 3224 LRPGD 3228
Score = 42.7 bits (96), Expect = 0.020
Identities = 44/178 (24%), Positives = 82/178 (46%), Gaps = 13/178 (7%)
Query: 181 NEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP-PEPSLLWYRDDQPVDESS 239
+++ + +L + + + V GL++VEA+ E T++V + + W RD +
Sbjct: 2063 DDKTQAKLTVEMRQVRLVRGLQAVEAR--EQGTATMEVQLSHADVDGSWTRDGLRFQQGP 2120
Query: 240 RCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN 299
CHL RG + L L + + F G ++ + +P + +P L++
Sbjct: 2121 TCHLAV--RGP--MHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRP--LQD 2174
Query: 300 LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCE 357
+ + +++ V LEC+ + P ++W KDG EL+ G I+ Q SL Y CE
Sbjct: 2175 V--VTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKT-MAIAAQGACRSLTIYRCE 2228
Score = 41.5 bits (93), Expect = 0.046
Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 20/241 (8%)
Query: 101 MENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAK 159
+E LQ V EG SF+C++ W G L+ ++ +T + K
Sbjct: 4253 LEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHK 4312
Query: 160 NCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVA 219
+ A TV + E +L++ +KN V GL++VEA F +++
Sbjct: 4313 VTLEDAG-----TVSFHVGTCSSEAQLKVTAKNTV---VRGLENVEALEGGEALFECQLS 4364
Query: 220 IPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P + W DD+PV S + E G+ L ++ L D +A G V
Sbjct: 4365 QPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLA----GDMV 4420
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVI-GVPQPVLKWYKDGEELKPG 336
TS FL + R ++ LE L+ GA C + VP WY +G ++P
Sbjct: 4421 TSAFLTV---RGWRL-EILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPD 4476
Query: 337 D 337
D
Sbjct: 4477 D 4477
Score = 39.9 bits (89), Expect = 0.14
Identities = 63/255 (24%), Positives = 103/255 (40%), Gaps = 26/255 (10%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
+F E L+ EG + + PV W K + L+ GD Y L G+ C +
Sbjct: 3451 KFTEGLRNEEAVEGATAMLWCELSKVAPV-EWRKGPENLRDGDRYIL---RQEGTRCELQ 3506
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ A + L V E L + +F+ +K+ EA+ E ++
Sbjct: 3507 ICGLAMADAGEYLCVCG-----QERTSATLTIRALPARFIEDVKNQEAR--EGATAVLQC 3559
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
+ + W + + + + R L +++ L I+ L D E+ CV GQ
Sbjct: 3560 ELNSAAPVEWRKGSETLRDGDRYSL-RQDGTKCELQIRGLAMADTGEYSCVC----GQER 3614
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGD 337
TS L + +F E L+ + EGA L C++ + PV +W+K E L+ GD
Sbjct: 3615 TSAMLTV----RALPIKFTEGLRNEEATEGATAVLRCELSKMA-PV-EWWKGHETLRDGD 3668
Query: 338 IHRIISGQDGT-CSL 351
H + QDG C L
Sbjct: 3669 RHSL--RQDGARCEL 3681
Score = 39.1 bits (87), Expect = 0.25
Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 24/238 (10%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
+F+E L+ EG + + PV W K + L+ GD + L S
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSKAAPV-EWRKGHETLRDGDRHSLRQDGS-------- 3765
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP-KFVHGLKSVEAKIDEPFRFTIK 217
C Q A + + +E + P +F+ +K+ EA+ E ++
Sbjct: 3766 -RCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAR--EGATAVLQ 3822
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+ + W + + + R L +++ L I L D E+ CV GQ
Sbjct: 3823 CELSKAAPVEWRKGSETLRGGDRYSL-RQDGTRCELQIHGLSVADTGEYSCVC----GQE 3877
Query: 278 VTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELK 334
TS L + P+ P F E LQ++ ++EG+ L+C+ + P + W K G +L+
Sbjct: 3878 RTSATLTVRAPQ----PVFREPLQSLQAEEGSTATLQCE-LSEPTATVVWSKGGLQLQ 3930
Score = 38.7 bits (86), Expect = 0.33
Identities = 61/290 (21%), Positives = 105/290 (36%), Gaps = 28/290 (9%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP 139
SI+M + P + N + A L EE + E + ++W KDG+ L P
Sbjct: 692 SIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAE---LSDQAAAVTWLKDGRTLSP 748
Query: 140 GDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED--IQNQLNEEEKLQLFSKNQAPKF 197
G Y++ S G + ++ + E I QL+ + + K+ A
Sbjct: 749 GPKYEVQA--SAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAG-- 804
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
V+A P +F + + + WY+D + S L ++ L
Sbjct: 805 ----SCVDAVAGGPAQFECETS-EAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAAT 859
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVI 317
+ D+ + C G+ L++ P+ L + + L C+V
Sbjct: 860 VTRQDEGTYSC----RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEV- 914
Query: 318 GVPQPVLKWYKDGEELK---------PGDIHRIISGQDGTCSLGTYTCEA 358
Q + WYKDG++L G R++ Q G G Y+CEA
Sbjct: 915 AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Score = 37.9 bits (84), Expect = 0.57
Identities = 51/245 (20%), Positives = 95/245 (38%), Gaps = 20/245 (8%)
Query: 128 LSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQ 187
++W KDG E++ ++ + + A S + E + EE
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEV-- 1807
Query: 188 LFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEE 247
A KF L+ V ++ +++ P ++W + + R + E
Sbjct: 1808 ------AAKFCRLLEPVCGELGGTVTLACELS-PACAEVVWRCGNTQLRVGKRFQM-VAE 1859
Query: 248 RGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDE 307
V L + L D E+ C + +D TS L + +PR K F+ L ++++E
Sbjct: 1860 GPVRSLTVLGLRAEDAGEYVCESRDDH----TSAQLTVSVPRVVK---FMSGLSTVVAEE 1912
Query: 308 GA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRII-SGQDGTCSLGTYTCEASNCMGVA 365
G +C V+ + W++DG L+P + I SG + ++ E + + V
Sbjct: 1913 GGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVE 1971
Query: 366 ASSAS 370
A AS
Sbjct: 1972 AEGAS 1976
Score = 37.1 bits (82), Expect = 1.00
Identities = 21/86 (24%), Positives = 34/86 (39%)
Query: 191 KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV 250
+ + P F H EA++ + R VA + W +D + + H+ + G
Sbjct: 4894 QQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGT 4953
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQ 276
L I L+ D + C N FGQ
Sbjct: 4954 CSLLITGLDRADAGCYTCQVSNKFGQ 4979
Score = 34.7 bits (76), Expect = 5.3
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 10/67 (14%)
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNC 361
L C V G P+P W KDG+ + G H + L G YTC ASN
Sbjct: 257 LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316
Query: 362 MGVAASS 368
+G SS
Sbjct: 317 VGQTYSS 323
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 80.2 bits (189), Expect = 1e-13
Identities = 94/349 (26%), Positives = 146/349 (41%), Gaps = 67/349 (19%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT- 146
P++ + P F+ LQ ++G VSF+C V G P P + WFKDG+ L+ D Y +
Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176
Query: 147 ---GTNSL----------GSYCCIAKNCMGQASSSAELTVE----DIQNQLNEEEKLQLF 189
G + L G Y C+A+N MG +S+ AEL V+ D + E F
Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236
Query: 190 S------------------KNQAPKFVHGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWYR 230
S + Q P+ V L+ ++ A +F +KV P P L W++
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH 290
D QP+ S+ + +++ + L+I ++ D ++ N G + +S L + P
Sbjct: 5297 DGQPLTASAHIRM-TDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355
Query: 291 YKK------------PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL---- 333
++ PR LE +G ++ KV G P P + W ++ E
Sbjct: 5356 PEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLW 5415
Query: 334 ----KPG-------DIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
PG H ++ G GTYTC ASN G A SASL
Sbjct: 5416 IGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASL 5464
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 17/189 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F L A++ E + +V P+P + WY+D + V L ++ G L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLE 313
+ +L +D ++ C A + G T + + +P PRF+ ++A EG
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 6128
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC----------SLGTYTCEASNCM 362
C + G P P ++WYKDG L G+ + +S + G LG Y CE N +
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188
Query: 363 GVAASSASL 371
G A +SA L
Sbjct: 6189 GSARASAEL 6197
Score = 65.7 bits (153), Expect = 2e-09
Identities = 51/193 (26%), Positives = 87/193 (45%), Gaps = 15/193 (7%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFL 253
AP+F+ K+ + + + ++ P P + W +D QPV +R L ++ ++ L
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA-QDGDLYRL 67
Query: 254 DIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR--HYKKPRFLENLQAILSDEGA-V 310
I L D ++ C A N G++ + L++ + P FL +I EG+
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEA 127
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-----------GTYTCEAS 359
C+V G P+P + W KDG L D R+ + G S GTY A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 360 NCMGVAASSASLL 372
N +G A+++A+L+
Sbjct: 188 NPLGAASAAAALV 200
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
+R P F E L E G V C+V G P PV+SW+KDG+ ++ D + + + GS
Sbjct: 6011 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGS 6069
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
I + G S + K+ + P+FV+ +++ E +
Sbjct: 6070 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV---QVPPRFVNKVRASPFVEGEDAQ 6126
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER-GVFFLDIQALEFLDQAEWKCVAFN 272
FT + P P + WY+D + ++ E R G+ L I+A D ++C N
Sbjct: 6127 FTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 6186
Query: 273 DFGQSVTSCFLKLIIP 288
G + S L++ P
Sbjct: 6187 RLGSARASAELRIQSP 6202
Score = 59.3 bits (137), Expect = 2e-07
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 26/201 (12%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLT- 146
PRF+ +A + G + C++VG PTP +SW KD Q + + GD+Y+LT
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 147 ---GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G Y C A+N +G+A ++ L V+ + QAP F+ S
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVD-----------AEAACAEQAPHFLLRPTS 118
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLD 262
+ + F +V P P++ W +D + + E + EE G L I+A D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 263 QAEWKCVAFNDFGQSVTSCFL 283
++ A N G + + L
Sbjct: 179 GGTYEVRAENPLGAASAAAAL 199
Score = 56.8 bits (131), Expect = 1e-06
Identities = 78/288 (27%), Positives = 129/288 (44%), Gaps = 38/288 (13%)
Query: 88 HPTVPKN-YRKPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N +QA ++S C+V T V +W+KDG++L
Sbjct: 1066 HITEPKMMFAKEQSVHNEVQAEAGASAMLS--CEVAQAQTEV-TWYKDGKKLSSSSK--- 1119
Query: 146 TGTNSLGSYCCIAKNCMGQASS---SAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G G + G+A + S E + + L+ E +F+K Q+ VH
Sbjct: 1120 VGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQS---VHN-- 1174
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFL 261
V+A+ + +VA P+ + WY+D + + SS+ + E +G L +Q +
Sbjct: 1175 EVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRM--EVKGCTRRLVVQQVGKA 1231
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YKKPRFLENLQAILSDEGA-VNLECKVIGV 319
D E+ C A GQ V S L + P+ + K + + N + ++ GA L C+V
Sbjct: 1232 DAGEYSCEAG---GQRV-SFQLHITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQA 1285
Query: 320 PQPVLKWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
Q + WYKDG++L G + +++ Q G G YTCEA
Sbjct: 1286 -QTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 54.8 bits (126), Expect = 5e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
++ P F E L ++ G V L C+V G P+PV+ WYKDG+ ++ H +I DG+C
Sbjct: 6011 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 6070
Query: 350 SL----------GTYTCEASNCMGVAASSASLL 372
+L G Y C A++ G ++ +L
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKIL 6103
Score = 53.2 bits (122), Expect = 1e-05
Identities = 67/271 (24%), Positives = 116/271 (42%), Gaps = 43/271 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGD-----VYQLTGTNSL 151
P F+ ++ EG +F C+V G P P +SW KDG+ L D V +L ++L
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASAL 169
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVED----------------IQNQLNEEEK 185
G+Y A+N +G AS++A L V+ + + E
Sbjct: 170 RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229
Query: 186 LQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGK 245
++ +P G ++ + R + V P+P +W +D Q V E R + +
Sbjct: 230 MRAEGAPASPPST-GTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYE 288
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI-L 304
+ + F L I + D+ + C A N GQ+ +S L++ R P F + LQ + +
Sbjct: 289 DAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV---LVVVREPAVP-FKKRLQDLEV 344
Query: 305 SDEGAVNLECKVIGVPQPVLK--WYKDGEEL 333
++ + C+ VPQP + W+K+ L
Sbjct: 345 REKESATFLCE---VPQPSTEAAWFKEETRL 372
Score = 51.2 bits (117), Expect = 6e-05
Identities = 61/255 (23%), Positives = 105/255 (41%), Gaps = 26/255 (10%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ C+V T V+ W+KDG++L + S E +
Sbjct: 1001 TLSCEVAQAQTEVM-WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ +L+ E +F+K Q+ VH V+A+ + +VA + + WY+D +
Sbjct: 1060 RVSFRLHITEPKMMFAKEQS---VHN--EVQAEAGASAMLSCEVA-QAQTEVTWYKDGKK 1113
Query: 235 VDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YK 292
+ SS+ +G E +G L + D E+ C A GQ V S L + P+ +
Sbjct: 1114 LSSSSK--VGMEVKGCTRRLVLPQAGKADAGEYSCEAG---GQRV-SFHLHITEPKGVFA 1167
Query: 293 KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELK---------PGDIHRIIS 343
K + + N + ++ G + + PQ + WYKDG++L G R++
Sbjct: 1168 KEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVV 1225
Query: 344 GQDGTCSLGTYTCEA 358
Q G G Y+CEA
Sbjct: 1226 QQVGKADAGEYSCEA 1240
Score = 50.0 bits (114), Expect = 1e-04
Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 35/277 (12%)
Query: 96 RKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSY 154
R RF E L+ + + E G + C + PV W L+PGD Y L ++
Sbjct: 3183 RPVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGDKYSLRQEGAMLEL 3241
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ +N Q S + D + L +F+ L++ EA E
Sbjct: 3242 --VVRNLRPQDSGRYSCSFGD------QTTSATLTVTALPAQFIGKLRNKEAT--EGATA 3291
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
T++ + + W + + + + R L +++ + L I+ L +D AE+ CV
Sbjct: 3292 TLRCELSKAAPVEWRKGSETLRDGDRYCL-RQDGAMCELQIRGLAMVDAAEYSCVC---- 3346
Query: 275 GQSVTSCFLKL-IIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEE 332
G+ TS L + +P H F+ L+ S EGA L C+ + PV +W K E
Sbjct: 3347 GEERTSASLTIRPMPAH-----FIGRLRHQESIEGATATLRCE-LSKAAPV-EWRKGRES 3399
Query: 333 LKPGDIHRIISGQDGTCSLGTYTCEASNCMGVAASSA 369
L+ GD H + QDG CE C G+A + A
Sbjct: 3400 LRDGDRHSL--RQDGA------VCELQIC-GLAVADA 3427
Score = 48.4 bits (110), Expect = 4e-04
Identities = 67/283 (23%), Positives = 108/283 (38%), Gaps = 28/283 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT 146
H T PK + K + + N V E G + V P ++W+KDG++L ++
Sbjct: 1158 HITEPKGVFAKEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRME 1215
Query: 147 GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
S E + + QL+ E +F+K Q VH EA
Sbjct: 1216 VKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQ---LVHNEVRTEA 1272
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAE 265
+ A + + WY+D + + SS+ + E G L +Q D E
Sbjct: 1273 GASATLSCEVAQA---QTEVTWYKDGKKLSSSSKVRI--EAAGCMRQLVVQQAGQADAGE 1327
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVL 324
+ C A G S L + P+ L + + + ++ GA+ L C+V Q +
Sbjct: 1328 YTCEA----GGQRLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQA-QTEV 1381
Query: 325 KWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
WYKDG++L G R++ Q G Y+CEA
Sbjct: 1382 TWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Score = 48.0 bits (109), Expect = 5e-04
Identities = 66/285 (23%), Positives = 111/285 (38%), Gaps = 28/285 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N V TE G + C+V T V +W+KDG++L ++
Sbjct: 1250 HITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQAQTEV-TWYKDGKKLSSSSKVRI 1306
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
+ + E + + L+ E +F+K Q H + V+
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQ---LAH--RKVQ 1361
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQA 264
A+ + +VA + + WY+D + + SS+ + E G L +Q D
Sbjct: 1362 AEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRM--EAVGCTRRLVVQQACQADTG 1418
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVL 324
E+ C A G S L + P+ + + + L C+V V+
Sbjct: 1419 EYSCEA----GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVM 1474
Query: 325 KWYKDGEELK---------PGDIHRIISGQDGTCSLGTYTCEASN 360
WYKDG++L G R++ Q G G Y+CEA +
Sbjct: 1475 -WYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGS 1518
Score = 46.4 bits (105), Expect = 0.002
Identities = 29/74 (39%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEA 358
A+ LEC V +W KDG EL G H I DGTCSL G YTC+
Sbjct: 4914 ALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQV 4973
Query: 359 SNCMGVAASSASLL 372
SN G SA ++
Sbjct: 4974 SNKFGQVTHSACVV 4987
Score = 45.6 bits (103), Expect = 0.003
Identities = 60/257 (23%), Positives = 103/257 (40%), Gaps = 30/257 (11%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASS---SAEL 171
+ C+V T V+ W+KDG++L ++ ++G + GQA + S E
Sbjct: 1461 TLSCEVAQAQTEVM-WYKDGKKLSFSSKVRM---EAVGCTRRLVVQQAGQAVAGEYSCEA 1516
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD 231
+ + L+ E +F+K Q + V+A+ + +VA + + WY+D
Sbjct: 1517 GSQRLSFHLHVAEPKAVFAKEQPAS-----REVQAEAGTSATLSCEVA-QAQTEVTWYKD 1570
Query: 232 DQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH 290
+ + SS+ + E G L +Q D E+ C A G S L + P+
Sbjct: 1571 GKKLSSSSKVRM--EAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVAEPKV 1624
Query: 291 YKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP---------GDIHRI 341
+ + + L C+V Q + WYKDG++L G R+
Sbjct: 1625 VFAKEQPAHREVQAEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRVEAVGCTRRL 1683
Query: 342 ISGQDGTCSLGTYTCEA 358
+ Q G G Y+CEA
Sbjct: 1684 VVQQAGQAEAGEYSCEA 1700
Score = 44.0 bits (99), Expect = 0.009
Identities = 55/245 (22%), Positives = 96/245 (39%), Gaps = 22/245 (8%)
Query: 96 RKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSY 154
R+ +E+L+ V +EG +F C++ + WF D L ++ ++ G Y
Sbjct: 3003 RRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQP--GGY 3060
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ + S I + ++ + P V + +A I E
Sbjct: 3061 HVLTLRQLALKDSGT------IYFEAGDQRASAALRVTEKPS-VFSRELTDATITEGEDL 3113
Query: 215 TIKVAIPP-EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T+ + + W +D + + S+RC L E L I D +KC A
Sbjct: 3114 TLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLL-ITGATLQDSGRYKCEA--- 3169
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G + +S +++ H + RF E L+ + + + GA L C + V PV KW
Sbjct: 3170 -GGACSSSIVRV----HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNV 3223
Query: 333 LKPGD 337
L+PGD
Sbjct: 3224 LRPGD 3228
Score = 42.7 bits (96), Expect = 0.020
Identities = 44/178 (24%), Positives = 82/178 (46%), Gaps = 13/178 (7%)
Query: 181 NEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP-PEPSLLWYRDDQPVDESS 239
+++ + +L + + + V GL++VEA+ E T++V + + W RD +
Sbjct: 2063 DDKTQAKLTVEMRQVRLVRGLQAVEAR--EQGTATMEVQLSHADVDGSWTRDGLRFQQGP 2120
Query: 240 RCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN 299
CHL RG + L L + + F G ++ + +P + +P L++
Sbjct: 2121 TCHLAV--RGP--MHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRP--LQD 2174
Query: 300 LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCE 357
+ + +++ V LEC+ + P ++W KDG EL+ G I+ Q SL Y CE
Sbjct: 2175 V--VTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKT-MAIAAQGACRSLTIYRCE 2228
Score = 41.5 bits (93), Expect = 0.046
Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 20/241 (8%)
Query: 101 MENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAK 159
+E LQ V EG SF+C++ W G L+ ++ +T + K
Sbjct: 4253 LEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHK 4312
Query: 160 NCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVA 219
+ A TV + E +L++ +KN V GL++VEA F +++
Sbjct: 4313 VTLEDAG-----TVSFHVGTCSSEAQLKVTAKNTV---VRGLENVEALEGGEALFECQLS 4364
Query: 220 IPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P + W DD+PV S + E G+ L ++ L D +A G V
Sbjct: 4365 QPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLA----GDMV 4420
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVI-GVPQPVLKWYKDGEELKPG 336
TS FL + R ++ LE L+ GA C + VP WY +G ++P
Sbjct: 4421 TSAFLTV---RGWRL-EILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPD 4476
Query: 337 D 337
D
Sbjct: 4477 D 4477
Score = 39.9 bits (89), Expect = 0.14
Identities = 63/255 (24%), Positives = 103/255 (40%), Gaps = 26/255 (10%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
+F E L+ EG + + PV W K + L+ GD Y L G+ C +
Sbjct: 3451 KFTEGLRNEEAVEGATAMLWCELSKVAPV-EWRKGPENLRDGDRYIL---RQEGTRCELQ 3506
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ A + L V E L + +F+ +K+ EA+ E ++
Sbjct: 3507 ICGLAMADAGEYLCVCG-----QERTSATLTIRALPARFIEDVKNQEAR--EGATAVLQC 3559
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
+ + W + + + + R L +++ L I+ L D E+ CV GQ
Sbjct: 3560 ELNSAAPVEWRKGSETLRDGDRYSL-RQDGTKCELQIRGLAMADTGEYSCVC----GQER 3614
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGD 337
TS L + +F E L+ + EGA L C++ + PV +W+K E L+ GD
Sbjct: 3615 TSAMLTV----RALPIKFTEGLRNEEATEGATAVLRCELSKMA-PV-EWWKGHETLRDGD 3668
Query: 338 IHRIISGQDGT-CSL 351
H + QDG C L
Sbjct: 3669 RHSL--RQDGARCEL 3681
Score = 39.1 bits (87), Expect = 0.25
Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 24/238 (10%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
+F+E L+ EG + + PV W K + L+ GD + L S
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSKAAPV-EWRKGHETLRDGDRHSLRQDGS-------- 3765
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP-KFVHGLKSVEAKIDEPFRFTIK 217
C Q A + + +E + P +F+ +K+ EA+ E ++
Sbjct: 3766 -RCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAR--EGATAVLQ 3822
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+ + W + + + R L +++ L I L D E+ CV GQ
Sbjct: 3823 CELSKAAPVEWRKGSETLRGGDRYSL-RQDGTRCELQIHGLSVADTGEYSCVC----GQE 3877
Query: 278 VTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELK 334
TS L + P+ P F E LQ++ ++EG+ L+C+ + P + W K G +L+
Sbjct: 3878 RTSATLTVRAPQ----PVFREPLQSLQAEEGSTATLQCE-LSEPTATVVWSKGGLQLQ 3930
Score = 38.7 bits (86), Expect = 0.33
Identities = 61/290 (21%), Positives = 105/290 (36%), Gaps = 28/290 (9%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP 139
SI+M + P + N + A L EE + E + ++W KDG+ L P
Sbjct: 692 SIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAE---LSDQAAAVTWLKDGRTLSP 748
Query: 140 GDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED--IQNQLNEEEKLQLFSKNQAPKF 197
G Y++ S G + ++ + E I QL+ + + K+ A
Sbjct: 749 GPKYEVQA--SAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAG-- 804
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
V+A P +F + + + WY+D + S L ++ L
Sbjct: 805 ----SCVDAVAGGPAQFECETS-EAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAAT 859
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVI 317
+ D+ + C G+ L++ P+ L + + L C+V
Sbjct: 860 VTRQDEGTYSC----RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEV- 914
Query: 318 GVPQPVLKWYKDGEELK---------PGDIHRIISGQDGTCSLGTYTCEA 358
Q + WYKDG++L G R++ Q G G Y+CEA
Sbjct: 915 AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Score = 37.9 bits (84), Expect = 0.57
Identities = 51/245 (20%), Positives = 95/245 (38%), Gaps = 20/245 (8%)
Query: 128 LSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQ 187
++W KDG E++ ++ + + A S + E + EE
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEV-- 1807
Query: 188 LFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEE 247
A KF L+ V ++ +++ P ++W + + R + E
Sbjct: 1808 ------AAKFCRLLEPVCGELGGTVTLACELS-PACAEVVWRCGNTQLRVGKRFQM-VAE 1859
Query: 248 RGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDE 307
V L + L D E+ C + +D TS L + +PR K F+ L ++++E
Sbjct: 1860 GPVRSLTVLGLRAEDAGEYVCESRDDH----TSAQLTVSVPRVVK---FMSGLSTVVAEE 1912
Query: 308 GA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRII-SGQDGTCSLGTYTCEASNCMGVA 365
G +C V+ + W++DG L+P + I SG + ++ E + + V
Sbjct: 1913 GGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVE 1971
Query: 366 ASSAS 370
A AS
Sbjct: 1972 AEGAS 1976
Score = 37.1 bits (82), Expect = 1.00
Identities = 21/86 (24%), Positives = 34/86 (39%)
Query: 191 KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV 250
+ + P F H EA++ + R VA + W +D + + H+ + G
Sbjct: 4894 QQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGT 4953
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQ 276
L I L+ D + C N FGQ
Sbjct: 4954 CSLLITGLDRADAGCYTCQVSNKFGQ 4979
Score = 34.7 bits (76), Expect = 5.3
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 10/67 (14%)
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNC 361
L C V G P+P W KDG+ + G H + L G YTC ASN
Sbjct: 257 LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316
Query: 362 MGVAASS 368
+G SS
Sbjct: 317 VGQTYSS 323
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 80.2 bits (189), Expect = 1e-13
Identities = 94/349 (26%), Positives = 146/349 (41%), Gaps = 67/349 (19%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT- 146
P++ + P F+ LQ ++G VSF+C V G P P + WFKDG+ L+ D Y +
Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176
Query: 147 ---GTNSL----------GSYCCIAKNCMGQASSSAELTVE----DIQNQLNEEEKLQLF 189
G + L G Y C+A+N MG +S+ AEL V+ D + E F
Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236
Query: 190 S------------------KNQAPKFVHGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWYR 230
S + Q P+ V L+ ++ A +F +KV P P L W++
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH 290
D QP+ S+ + +++ + L+I ++ D ++ N G + +S L + P
Sbjct: 5297 DGQPLTASAHIRM-TDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDE 5355
Query: 291 YKK------------PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL---- 333
++ PR LE +G ++ KV G P P + W ++ E
Sbjct: 5356 PEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLW 5415
Query: 334 ----KPG-------DIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
PG H ++ G GTYTC ASN G A SASL
Sbjct: 5416 IGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASL 5464
Score = 67.7 bits (158), Expect = 6e-10
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 17/189 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F L A++ E + +V P+P + WY+D + V L ++ G L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLE 313
+ +L +D ++ C A + G T + + +P PRF+ + A EG
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVLASPFVEGEDAQFT 6128
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC----------SLGTYTCEASNCM 362
C + G P P ++WYKDG L G+ + +S + G LG Y CE N +
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188
Query: 363 GVAASSASL 371
G A +SA L
Sbjct: 6189 GSARASAEL 6197
Score = 66.1 bits (154), Expect = 2e-09
Identities = 51/193 (26%), Positives = 87/193 (45%), Gaps = 15/193 (7%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFL 253
AP+F+ K+ + + + ++ P P + W +D QPV +R L ++ ++ L
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLA-QDGDLYRL 67
Query: 254 DIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR--HYKKPRFLENLQAILSDEGA-V 310
I L D ++ C A N G++ + L++ + P FL +I EG+
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEA 127
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-----------GTYTCEAS 359
C+V G P+P + W KDG L D R+ + G S GTY A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 360 NCMGVAASSASLL 372
N +G A+++A+L+
Sbjct: 188 NPLGAASAAAALV 200
Score = 61.7 bits (143), Expect = 4e-08
Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 6/196 (3%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
+R P F E L E G V C+V G P PV+SW+KDG+ ++ D + + + GS
Sbjct: 6011 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGS 6069
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
I + G S + K+ + P+FV+ + + E +
Sbjct: 6070 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV---QVPPRFVNKVLASPFVEGEDAQ 6126
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER-GVFFLDIQALEFLDQAEWKCVAFN 272
FT + P P + WY+D + ++ E R G+ L I+A D ++C N
Sbjct: 6127 FTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 6186
Query: 273 DFGQSVTSCFLKLIIP 288
G + S L++ P
Sbjct: 6187 RLGSARASAELRIQSP 6202
Score = 59.3 bits (137), Expect = 2e-07
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 26/201 (12%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLT- 146
PRF+ +A + G + C++VG PTP +SW KD Q + + GD+Y+LT
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTI 69
Query: 147 ---GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G Y C A+N +G+A ++ L V+ + QAP F+ S
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVD-----------AEAACAEQAPHFLLRPTS 118
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLD 262
+ + F +V P P++ W +D + + E + EE G L I+A D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 263 QAEWKCVAFNDFGQSVTSCFL 283
++ A N G + + L
Sbjct: 179 GGTYEVRAENPLGAASAAAAL 199
Score = 56.8 bits (131), Expect = 1e-06
Identities = 78/288 (27%), Positives = 129/288 (44%), Gaps = 38/288 (13%)
Query: 88 HPTVPKN-YRKPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N +QA ++S C+V T V +W+KDG++L
Sbjct: 1066 HITEPKMMFAKEQSVHNEVQAEAGASAMLS--CEVAQAQTEV-TWYKDGKKLSSSSK--- 1119
Query: 146 TGTNSLGSYCCIAKNCMGQASS---SAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G G + G+A + S E + + L+ E +F+K Q+ VH
Sbjct: 1120 VGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQS---VHN-- 1174
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFL 261
V+A+ + +VA P+ + WY+D + + SS+ + E +G L +Q +
Sbjct: 1175 EVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRM--EVKGCTRRLVVQQVGKA 1231
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YKKPRFLENLQAILSDEGA-VNLECKVIGV 319
D E+ C A GQ V S L + P+ + K + + N + ++ GA L C+V
Sbjct: 1232 DAGEYSCEAG---GQRV-SFQLHITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQA 1285
Query: 320 PQPVLKWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
Q + WYKDG++L G + +++ Q G G YTCEA
Sbjct: 1286 -QTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 54.8 bits (126), Expect = 5e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
++ P F E L ++ G V L C+V G P+PV+ WYKDG+ ++ H +I DG+C
Sbjct: 6011 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 6070
Query: 350 SL----------GTYTCEASNCMGVAASSASLL 372
+L G Y C A++ G ++ +L
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKIL 6103
Score = 53.2 bits (122), Expect = 1e-05
Identities = 67/271 (24%), Positives = 116/271 (42%), Gaps = 43/271 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGD-----VYQLTGTNSL 151
P F+ ++ EG +F C+V G P P +SW KDG+ L D V +L ++L
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASAL 169
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVED----------------IQNQLNEEEK 185
G+Y A+N +G AS++A L V+ + + E
Sbjct: 170 RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229
Query: 186 LQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGK 245
++ +P G ++ + R + V P+P +W +D Q V E R + +
Sbjct: 230 MRAEGAPASPPST-GTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYE 288
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI-L 304
+ + F L I + D+ + C A N GQ+ +S L++ R P F + LQ + +
Sbjct: 289 DAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV---LVVVREPAVP-FKKRLQDLEV 344
Query: 305 SDEGAVNLECKVIGVPQPVLK--WYKDGEEL 333
++ + C+ VPQP + W+K+ L
Sbjct: 345 REKESATFLCE---VPQPSTEAAWFKEETRL 372
Score = 50.0 bits (114), Expect = 1e-04
Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 35/277 (12%)
Query: 96 RKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSY 154
R RF E L+ + + E G + C + PV W L+PGD Y L ++
Sbjct: 3183 RPVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNVLRPGDKYSLRQEGAMLEL 3241
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ +N Q S + D + L +F+ L++ EA E
Sbjct: 3242 --VVRNLRPQDSGRYSCSFGD------QTTSATLTVTALPAQFIGKLRNKEAT--EGATA 3291
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
T++ + + W + + + + R L +++ + L I+ L +D AE+ CV
Sbjct: 3292 TLRCELSKTAPVEWRKGSETLRDGDRYCL-RQDGAMCELQIRGLAMVDAAEYSCVC---- 3346
Query: 275 GQSVTSCFLKL-IIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEE 332
G+ TS L + +P H F+ L+ S EGA L C+ + PV +W K E
Sbjct: 3347 GEERTSASLTIRPMPAH-----FIGRLRHQESIEGATATLRCE-LSKAAPV-EWRKGRES 3399
Query: 333 LKPGDIHRIISGQDGTCSLGTYTCEASNCMGVAASSA 369
L+ GD H + QDG CE C G+A + A
Sbjct: 3400 LRDGDRHSL--RQDGA------VCELQIC-GLAVADA 3427
Score = 49.2 bits (112), Expect = 2e-04
Identities = 60/255 (23%), Positives = 104/255 (40%), Gaps = 26/255 (10%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ C+V V+ W+KDG++L + S E +
Sbjct: 1001 TLSCEVAQAQAEVM-WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ +L+ E +F+K Q+ VH V+A+ + +VA + + WY+D +
Sbjct: 1060 RVSFRLHITEPKMMFAKEQS---VHN--EVQAEAGASAMLSCEVA-QAQTEVTWYKDGKK 1113
Query: 235 VDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YK 292
+ SS+ +G E +G L + D E+ C A GQ V S L + P+ +
Sbjct: 1114 LSSSSK--VGMEVKGCTRRLVLPQAGKADAGEYSCEAG---GQRV-SFHLHITEPKGVFA 1167
Query: 293 KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELK---------PGDIHRIIS 343
K + + N + ++ G + + PQ + WYKDG++L G R++
Sbjct: 1168 KEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVV 1225
Query: 344 GQDGTCSLGTYTCEA 358
Q G G Y+CEA
Sbjct: 1226 QQVGKADAGEYSCEA 1240
Score = 48.8 bits (111), Expect = 3e-04
Identities = 66/285 (23%), Positives = 111/285 (38%), Gaps = 28/285 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N V TE G + C+V T V +W+KDG++L ++
Sbjct: 1250 HITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQAQTEV-TWYKDGKKLSSSSKVRI 1306
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
+ + E + + L+ E +F+K Q H + V+
Sbjct: 1307 EAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQ---LAH--RKVQ 1361
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQA 264
A+ + +VA + + WY+D + + SS+ + E G L +Q D
Sbjct: 1362 AEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRM--EAVGCTRRLVVQQACQADTG 1418
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVL 324
E+ C A G S L + P+ + + + L C+V V+
Sbjct: 1419 EYSCEA----GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVM 1474
Query: 325 KWYKDGEELK---------PGDIHRIISGQDGTCSLGTYTCEASN 360
WYKDG++L G R++ Q G G Y+CEA +
Sbjct: 1475 -WYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQADAGEYSCEAGS 1518
Score = 48.4 bits (110), Expect = 4e-04
Identities = 67/283 (23%), Positives = 108/283 (38%), Gaps = 28/283 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT 146
H T PK + K + + N V E G + V P ++W+KDG++L ++
Sbjct: 1158 HITEPKGVFAKEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRME 1215
Query: 147 GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
S E + + QL+ E +F+K Q VH EA
Sbjct: 1216 VKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQ---LVHNEVRTEA 1272
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAE 265
+ A + + WY+D + + SS+ + E G L +Q D E
Sbjct: 1273 GASATLSCEVAQA---QTEVTWYKDGKKLSSSSKVRI--EAAGCMRQLVVQQAGQADAGE 1327
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVL 324
+ C A G S L + P+ L + + + ++ GA+ L C+V Q +
Sbjct: 1328 YTCEA----GGQRLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQA-QTEV 1381
Query: 325 KWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
WYKDG++L G R++ Q G Y+CEA
Sbjct: 1382 TWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Score = 46.4 bits (105), Expect = 0.002
Identities = 60/257 (23%), Positives = 103/257 (40%), Gaps = 30/257 (11%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASS---SAEL 171
+ C+V T V+ W+KDG++L ++ ++G + GQA + S E
Sbjct: 1461 TLSCEVAQAQTEVM-WYKDGKKLSFSSKVRM---EAVGCTRRLVVQQAGQADAGEYSCEA 1516
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD 231
+ + L+ E +F+K Q + V+A+ + +VA + + WY+D
Sbjct: 1517 GSQRLSFHLHVAEPKAVFAKEQPAS-----REVQAEAGTSATLSCEVA-QAQTEVTWYKD 1570
Query: 232 DQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH 290
+ + SS+ + E G L +Q D E+ C A G S L + P+
Sbjct: 1571 GKKLSSSSKVRM--EAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVAEPKV 1624
Query: 291 YKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP---------GDIHRI 341
+ + + L C+V Q + WYKDG++L G R+
Sbjct: 1625 VFAKEQPAHREVQAEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRVEAVGCTRRL 1683
Query: 342 ISGQDGTCSLGTYTCEA 358
+ Q G G Y+CEA
Sbjct: 1684 VVQQAGQADAGEYSCEA 1700
Score = 46.4 bits (105), Expect = 0.002
Identities = 29/74 (39%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEA 358
A+ LEC V +W KDG EL G H I DGTCSL G YTC+
Sbjct: 4914 ALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLIAGLDRADAGCYTCQV 4973
Query: 359 SNCMGVAASSASLL 372
SN G SA ++
Sbjct: 4974 SNKFGQVTHSACVV 4987
Score = 44.4 bits (100), Expect = 0.007
Identities = 55/245 (22%), Positives = 96/245 (39%), Gaps = 22/245 (8%)
Query: 96 RKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSY 154
R+ +E+L+ V +EG +F C++ + WF D L ++ ++ G Y
Sbjct: 3003 RRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQP--GGY 3060
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ + S I + ++ + P V + +A I E
Sbjct: 3061 HVLTLRQLALKDSGT------IYFEAGDQRASAALRVTEKPS-VFSRELTDATITEGEDL 3113
Query: 215 TIKVAIPP-EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
T+ + + W +D + + S+RC L E L I D +KC A
Sbjct: 3114 TLVCETSTCDIPMCWTKDGKTLRGSARCQLSHEGHRAQLL-ITGATLQDSGRYKCEA--- 3169
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G + +S +++ H + RF E L+ + + + GA L C + V PV KW
Sbjct: 3170 -GGACSSSIVRV----HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAPV-KWCYGNNV 3223
Query: 333 LKPGD 337
L+PGD
Sbjct: 3224 LRPGD 3228
Score = 42.7 bits (96), Expect = 0.020
Identities = 44/178 (24%), Positives = 82/178 (46%), Gaps = 13/178 (7%)
Query: 181 NEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP-PEPSLLWYRDDQPVDESS 239
+++ + +L + + + V GL++VEA+ E T++V + + W RD +
Sbjct: 2063 DDKTQAKLTVEMRQVRLVRGLQAVEAR--EQGTATMEVQLSHADVDGSWTRDGLRFQQGP 2120
Query: 240 RCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN 299
CHL RG + L L + + F G ++ + +P + +P L++
Sbjct: 2121 TCHLAV--RGP--MHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRP--LQD 2174
Query: 300 LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCE 357
+ + +++ V LEC+ + P ++W KDG EL+ G I+ Q SL Y CE
Sbjct: 2175 V--VTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKT-MAIAAQGACRSLTIYRCE 2228
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 20/241 (8%)
Query: 101 MENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAK 159
+E LQ V EG SF+C++ W G L+ ++ +T + K
Sbjct: 4253 LEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHK 4312
Query: 160 NCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVA 219
+ A TV + E +L++ +KN V GL++VEA F +++
Sbjct: 4313 VTLEDAG-----TVSFHVGTCSSEAQLKVTAKNTV---VRGLENVEALEGGEALFECQLS 4364
Query: 220 IPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P + W DD+PV S + E G+ L ++ L D +A G V
Sbjct: 4365 QPEVAAHTWLLDDEPVRTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLA----GDMV 4420
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVI-GVPQPVLKWYKDGEELKPG 336
TS FL + R ++ LE L+ GA C + VP WY +G ++P
Sbjct: 4421 TSAFLTV---RGWRL-EILEPLKNAAVRAGAQARFTCTLSEAVPVGEASWYINGAAVQPD 4476
Query: 337 D 337
D
Sbjct: 4477 D 4477
Score = 41.1 bits (92), Expect = 0.061
Identities = 63/272 (23%), Positives = 105/272 (38%), Gaps = 27/272 (9%)
Query: 96 RKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSY 154
R +FM L V+ EEG +F+C V V+ WF+DG L+P + + ++ + + S
Sbjct: 1897 RVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVV-WFRDGALLQPSEKFAISQSGASHSL 1955
Query: 155 CC--IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
+ GQ + AE L E LF K P+ V SV +++
Sbjct: 1956 TISDLVLEDAGQITVEAEGASSSA--ALRVREAPVLFKKKLEPQTVEERSSVTLEVE--- 2010
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
P P L W R+ + + E L + + F D+ + C +
Sbjct: 2011 ------LTRPWPELRWTRNATALAPGKNVEI-HAEGARHRLVLHNVGFADRGFFGCETPD 2063
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGE 331
D Q+ KL + ++ R + LQA+ ++G +E ++ W +DG
Sbjct: 2064 DKTQA------KLTV--EMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDG-SWTRDGL 2114
Query: 332 ELKPG-DIHRIISGQDGTCSLGTYTCEASNCM 362
+ G H + G T +L E S M
Sbjct: 2115 RFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLM 2146
Score = 39.9 bits (89), Expect = 0.14
Identities = 63/255 (24%), Positives = 103/255 (40%), Gaps = 26/255 (10%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
+F E L+ EG + + PV W K + L+ GD Y L G+ C +
Sbjct: 3451 KFTEGLRNEEAVEGATAMLWCELSKVAPV-EWRKGPENLRDGDRYIL---RQEGTRCELQ 3506
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ A + L V E L + +F+ +K+ EA+ E ++
Sbjct: 3507 ICGLAMADAGEYLCVCG-----QERTSATLTIRALPARFIEDVKNQEAR--EGATAVLQC 3559
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
+ + W + + + + R L +++ L I+ L D E+ CV GQ
Sbjct: 3560 ELNSAAPVEWRKGSETLRDGDRYSL-RQDGTKCELQIRGLAMADTGEYSCVC----GQER 3614
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVN-LECKVIGVPQPVLKWYKDGEELKPGD 337
TS L + +F E L+ + EGA L C++ + PV +W+K E L+ GD
Sbjct: 3615 TSAMLTV----RALPIKFTEGLRNEEATEGATAVLRCELSKMA-PV-EWWKGHETLRDGD 3668
Query: 338 IHRIISGQDGT-CSL 351
H + QDG C L
Sbjct: 3669 RHSL--RQDGARCEL 3681
Score = 39.1 bits (87), Expect = 0.25
Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 24/238 (10%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
+F+E L+ EG + + PV W K + L+ GD + L S
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSKAAPV-EWRKGHETLRDGDRHSLRQDGS-------- 3765
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP-KFVHGLKSVEAKIDEPFRFTIK 217
C Q A + + +E + P +F+ +K+ EA+ E ++
Sbjct: 3766 -RCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAR--EGATAVLQ 3822
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+ + W + + + R L +++ L I L D E+ CV GQ
Sbjct: 3823 CELSKAAPVEWRKGSETLRGGDRYSL-RQDGTRCELQIHGLSVADTGEYSCVC----GQE 3877
Query: 278 VTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELK 334
TS L + P+ P F E LQ++ ++EG+ L+C+ + P + W K G +L+
Sbjct: 3878 RTSATLTVRAPQ----PVFREPLQSLQAEEGSTATLQCE-LSEPTATVVWSKGGLQLQ 3930
Score = 38.7 bits (86), Expect = 0.33
Identities = 61/290 (21%), Positives = 105/290 (36%), Gaps = 28/290 (9%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP 139
SI+M + P + N + A L EE + E + ++W KDG+ L P
Sbjct: 692 SIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAE---LSDQAAAVTWLKDGRTLSP 748
Query: 140 GDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED--IQNQLNEEEKLQLFSKNQAPKF 197
G Y++ S G + ++ + E I QL+ + + K+ A
Sbjct: 749 GPKYEVQA--SAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAG-- 804
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
V+A P +F + + + WY+D + S L ++ L
Sbjct: 805 ----SCVDAVAGGPAQFECETS-EAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAAT 859
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVI 317
+ D+ + C G+ L++ P+ L + + L C+V
Sbjct: 860 VTRQDEGTYSC----RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEV- 914
Query: 318 GVPQPVLKWYKDGEELK---------PGDIHRIISGQDGTCSLGTYTCEA 358
Q + WYKDG++L G R++ Q G G Y+CEA
Sbjct: 915 AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA 964
Score = 37.1 bits (82), Expect = 1.00
Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 10/120 (8%)
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VN 311
L + L D E+ C + +D TS L + +PR K F+ L ++++EG
Sbjct: 1865 LTVLGLRAEDAGEYVCESRDDH----TSAQLTVSVPRVVK---FMSGLSTVVAEEGGEAT 1917
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHRII-SGQDGTCSLGTYTCEASNCMGVAASSAS 370
+C V+ + W++DG L+P + I SG + ++ E + + V A AS
Sbjct: 1918 FQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGAS 1976
Score = 37.1 bits (82), Expect = 1.00
Identities = 21/86 (24%), Positives = 34/86 (39%)
Query: 191 KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV 250
+ + P F H EA++ + R VA + W +D + + H+ + G
Sbjct: 4894 QQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGT 4953
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQ 276
L I L+ D + C N FGQ
Sbjct: 4954 CSLLIAGLDRADAGCYTCQVSNKFGQ 4979
Score = 34.7 bits (76), Expect = 5.3
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 10/67 (14%)
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNC 361
L C V G P+P W KDG+ + G H + L G YTC ASN
Sbjct: 257 LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316
Query: 362 MGVAASS 368
+G SS
Sbjct: 317 VGQTYSS 323
>AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein.
Length = 1040
Score = 79.4 bits (187), Expect = 2e-13
Identities = 94/350 (26%), Positives = 146/350 (41%), Gaps = 68/350 (19%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT- 146
P++ + P F+ LQ ++G VSF+C V G P P + WFKDG+ L+ D Y +
Sbjct: 688 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 747
Query: 147 ---GTNSL----------GSYCCIAKNCMGQASSSAELTVE----DIQNQLNEEEKLQLF 189
G + L G Y C+A+N MG +S+ AEL V+ D + E F
Sbjct: 748 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 807
Query: 190 S-------------------KNQAPKFVHGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWY 229
S + Q P+ V L+ ++ A +F +KV P P L W+
Sbjct: 808 SAQGYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF 867
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
+D QP+ S+ + +++ + L+I ++ D ++ N G + +S L + P
Sbjct: 868 KDGQPLTASAHIRM-TDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD 926
Query: 290 HYKK------------PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL--- 333
++ PR LE +G ++ KV G P P + W ++ E
Sbjct: 927 EPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVL 986
Query: 334 -----KPG-------DIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
PG H ++ G GTYTC ASN G A SASL
Sbjct: 987 WIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASL 1036
Score = 46.4 bits (105), Expect = 0.002
Identities = 29/74 (39%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 309 AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEA 358
A+ LEC V +W KDG EL G H I DGTCSL G YTC+
Sbjct: 485 ALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQV 544
Query: 359 SNCMGVAASSASLL 372
SN G SA ++
Sbjct: 545 SNKFGQVTHSACVV 558
Score = 37.1 bits (82), Expect = 1.00
Identities = 21/86 (24%), Positives = 34/86 (39%)
Query: 191 KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV 250
+ + P F H EA++ + R VA + W +D + + H+ + G
Sbjct: 465 QQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGT 524
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQ 276
L I L+ D + C N FGQ
Sbjct: 525 CSLLITGLDRADAGCYTCQVSNKFGQ 550
>BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein.
Length = 637
Score = 77.0 bits (181), Expect = 1e-12
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVF 251
QAP F L+SV F ++ P P + W+RD Q + S+ + G
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-V 310
L I A+ + + A N GQ+ ++ +L++ P F++ LQ++ +G+ V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTA--ELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 311 NLECKVIGVPQPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNC 361
L+ +V G+P PV+K+Y+DG E+ + GD++ ++ + GTY+ A+N
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 362 MGVAASSASLL 372
+G A S+A LL
Sbjct: 182 VGRATSTAELL 192
Score = 60.5 bits (140), Expect = 9e-08
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 2/187 (1%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + LQ+V+ EG +FE + GFP P +SWF+DGQ + + + + S G
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
S L + Q +L + ++ P FV L+S+ + R +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+V P P + +YRD + S + +E ++ L I D + A N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 277 SVTSCFL 283
+ ++ L
Sbjct: 185 ATSTAEL 191
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/91 (32%), Positives = 51/91 (56%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQLTG 147
P F++ LQ++ +G V + +V G PTPV+ +++DG E++ GD+Y L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVE 174
+ G+Y A N +G+A+S+AEL V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
>BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein.
Length = 558
Score = 77.0 bits (181), Expect = 1e-12
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVF 251
QAP F L+SV F ++ P P + W+RD Q + S+ + G
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-V 310
L I A+ + + A N GQ+ ++ +L++ P F++ LQ++ +G+ V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTA--ELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 311 NLECKVIGVPQPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNC 361
L+ +V G+P PV+K+Y+DG E+ + GD++ ++ + GTY+ A+N
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 362 MGVAASSASLL 372
+G A S+A LL
Sbjct: 182 VGRATSTAELL 192
Score = 60.5 bits (140), Expect = 9e-08
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 2/187 (1%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + LQ+V+ EG +FE + GFP P +SWF+DGQ + + + + S G
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
S L + Q +L + ++ P FV L+S+ + R +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+V P P + +YRD + S + +E ++ L I D + A N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 277 SVTSCFL 283
+ ++ L
Sbjct: 185 ATSTAEL 191
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/91 (32%), Positives = 51/91 (56%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQLTG 147
P F++ LQ++ +G V + +V G PTPV+ +++DG E++ GD+Y L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVE 174
+ G+Y A N +G+A+S+AEL V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
>BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein.
Length = 305
Score = 77.0 bits (181), Expect = 1e-12
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVF 251
QAP F L+SV F ++ P P + W+RD Q + S+ + G
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-V 310
L I A+ + + A N GQ+ ++ +L++ P F++ LQ++ +G+ V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTA--ELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 311 NLECKVIGVPQPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNC 361
L+ +V G+P PV+K+Y+DG E+ + GD++ ++ + GTY+ A+N
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 362 MGVAASSASLL 372
+G A S+A LL
Sbjct: 182 VGRATSTAELL 192
Score = 60.5 bits (140), Expect = 9e-08
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 2/187 (1%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + LQ+V+ EG +FE + GFP P +SWF+DGQ + + + + S G
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
S L + Q +L + ++ P FV L+S+ + R +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+V P P + +YRD + S + +E ++ L I D + A N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 277 SVTSCFL 283
+ ++ L
Sbjct: 185 ATSTAEL 191
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/91 (32%), Positives = 51/91 (56%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQLTG 147
P F++ LQ++ +G V + +V G PTPV+ +++DG E++ GD+Y L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVE 174
+ G+Y A N +G+A+S+AEL V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
>AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform
protein.
Length = 5604
Score = 77.0 bits (181), Expect = 1e-12
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVF 251
QAP F L+SV F ++ P P + W+RD Q + S+ + G
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-V 310
L I A+ + + A N GQ+ ++ +L++ P F++ LQ++ +G+ V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTA--ELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 311 NLECKVIGVPQPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNC 361
L+ +V G+P PV+K+Y+DG E+ + GD++ ++ + GTY+ A+N
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 362 MGVAASSASLL 372
+G A S+A LL
Sbjct: 182 VGRATSTAELL 192
Score = 70.5 bits (165), Expect = 9e-11
Identities = 54/198 (27%), Positives = 91/198 (45%), Gaps = 22/198 (11%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+ + L+ V + +P RF ++ P+P + WY+++Q + +C + +
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK--------KPRFLENLQAIL 304
L I+A D A + C A ND+G + TS L + +P P + LQ +
Sbjct: 3297 LLIEAFP-EDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3355
Query: 305 SDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GT 353
+ EG +C+V G V WY +++KP R+ +D T L GT
Sbjct: 3356 TSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGT 3413
Query: 354 YTCEASNCMGVAASSASL 371
YT ASN +G +S+A+L
Sbjct: 3414 YTFVASNAVGQVSSTANL 3431
Score = 66.5 bits (155), Expect = 1e-09
Identities = 50/175 (28%), Positives = 77/175 (44%), Gaps = 3/175 (1%)
Query: 179 QLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES 238
+L E ++ QL + P FV S + + RF +KV P P W+ D Q +
Sbjct: 1442 RLEETDESQL-ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVND 1500
Query: 239 SRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLE 298
+ +E G L I D EW VA N G+S S L + H KP F+E
Sbjct: 1501 YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560
Query: 299 NLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL 351
L+ + EG+ + ++ + G P P + W K+ + + P +I I G G +L
Sbjct: 1561 KLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL 1615
Score = 62.5 bits (145), Expect = 2e-08
Identities = 60/249 (24%), Positives = 106/249 (42%), Gaps = 13/249 (5%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYC 155
P+ E +Q+ +G F +VVG P P W+K+G +++ D +Y +++
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE-- 2135
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
+ ++ + S+S + +I + + L L Q F L+ V AK +
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLITFTQELQDVVAKEKDTMATF 2194
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
P + WY+D V E + + +R V FL I ++ D ++ CV D
Sbjct: 2195 ECETSEPFVKVKWYKDGMEVHEGDKYRM-HSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2253
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELK 334
T+ KLI+ + F++ LQ I + + + LEC ++ KWY + ELK
Sbjct: 2254 VKTTA---KLIVEGAVVE--FVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELK 2307
Query: 335 PGDIHRIIS 343
+ I S
Sbjct: 2308 SNGKYTITS 2316
Score = 60.5 bits (140), Expect = 9e-08
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 2/187 (1%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + LQ+V+ EG +FE + GFP P +SWF+DGQ + + + + S G
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
S L + Q +L + ++ P FV L+S+ + R +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+V P P + +YRD + S + +E ++ L I D + A N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 277 SVTSCFL 283
+ ++ L
Sbjct: 185 ATSTAEL 191
Score = 59.3 bits (137), Expect = 2e-07
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 6/162 (3%)
Query: 184 EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
+K++L +APK ++S F ++V P+P WY++ ++ S R +
Sbjct: 2067 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2126
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI 303
E V L I+ + D A A N G++ + FL + + + F + LQ +
Sbjct: 2127 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL---LVQAKQLITFTQELQDV 2183
Query: 304 LSDE--GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
++ E EC+ P +KWYKDG E+ GD +R+ S
Sbjct: 2184 VAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHS 2224
Score = 59.3 bits (137), Expect = 2e-07
Identities = 61/225 (27%), Positives = 100/225 (44%), Gaps = 38/225 (16%)
Query: 98 PRF-MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLT---GTNSL- 151
PRF M + E F+C V+G PTP + W+K+ ++P ++ Y ++ G+++L
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQ-------------NQLNEEEKLQL- 188
+Y C A NC+G+A LT+ D + + L EE L+
Sbjct: 5440 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSN 5499
Query: 189 ----FSKNQA----PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
F + Q P+F+ G+ A I F V P P++ WY+D + V + R
Sbjct: 5500 YTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRR 5558
Query: 241 CHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ + G L I +L D+ E++CVA N G + + L L
Sbjct: 5559 FTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 58.4 bits (135), Expect = 4e-07
Identities = 70/255 (27%), Positives = 114/255 (44%), Gaps = 31/255 (12%)
Query: 100 FMENLQAVLTEEG--LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
F + LQ V+ +E + +FEC+ P + W+KDG E+ GD Y++ + + I
Sbjct: 2176 FTQELQDVVAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKV-HFLSI 2233
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
A + + VED N + +L + +FV L+ +E + E + ++
Sbjct: 2234 LTIDTSDAEDYSCVLVEDE----NVKTTAKLIVEGAVVEFVKELQDIE--VPESYSGELE 2287
Query: 218 VAIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+ PE WY +D + + + + RG L ++ + DQ E+ V
Sbjct: 2288 CIVSPENIEGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFV----IDG 2342
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSD----EG-AVNLECKVIGVPQPVLKWYKDGE 331
T+C LK+ KPR + LQ LSD EG V LE KV + W KDG+
Sbjct: 2343 KKTTCKLKM-------KPRPIAILQG-LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQ 2393
Query: 332 ELKPGD-IHRIISGQ 345
E++P D +H +I Q
Sbjct: 2394 EVQPSDRVHIVIDKQ 2408
Score = 57.2 bits (132), Expect = 9e-07
Identities = 84/302 (27%), Positives = 124/302 (41%), Gaps = 53/302 (17%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ---------------LTGTNSLG 152
L E G V F C+V G P P + W K G L G Y+ +T + G
Sbjct: 1093 LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1152
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA------ 206
Y + +N G+ S+SA L +E+ +L + + ++ + Q FV K E
Sbjct: 1153 EYTIVVRNKHGETSASASL-LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVY 1211
Query: 207 ----KIDEPFRFTIKVAIPPEPSLL-WYRDDQPVDESS-RCHLGKE-ERGVFFLDIQALE 259
K E + I+ + + ++ Y +DQ SS L KE E + ++ L
Sbjct: 1212 SEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELL 1271
Query: 260 FLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D E V ++ ++V S F I K R LE + V CK+ G
Sbjct: 1272 EEDGEEKMAVDISE-SEAVESGFDLRI-----KNYRILEGM--------GVTFHCKMSGY 1317
Query: 320 PQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSA 369
P P + WYKDG+ +K G+ +++ QDG SL G YT ASN G A S
Sbjct: 1318 PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSG 1377
Query: 370 SL 371
L
Sbjct: 1378 KL 1379
Score = 56.4 bits (130), Expect = 2e-06
Identities = 53/201 (26%), Positives = 84/201 (41%), Gaps = 29/201 (14%)
Query: 97 KPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL 151
KP F+ + EG + F+ KVVG P P WF DGQ++ +++ GT SL
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL 201
G + +A+N G++S S LTVE +++Q+ P FV L
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVK-------------PMFVEKL 1562
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVFFLDIQALEF 260
K+V K ++ P P ++W ++ + + E +G L I +
Sbjct: 1563 KNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVS 1622
Query: 261 LDQAEWKCVAFNDFGQSVTSC 281
D A + A N G+ T C
Sbjct: 1623 QDSAWYTATAINKAGRDTTRC 1643
Score = 54.0 bits (124), Expect = 8e-06
Identities = 53/218 (24%), Positives = 95/218 (43%), Gaps = 21/218 (9%)
Query: 98 PRFMENLQAVLTEEGLVSFECKVV-GFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ ++ LQ V + G + C V+ G P P +SW+K+ Q L G Y L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3298
Query: 148 TNSLGS----YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+ Y C AKN G A++SA L+VE + ++ ++++ ++ P + L+
Sbjct: 3299 IEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVY----PPAIITPLQD 3353
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+P RF +V+ + + WY D+ + + SR + + L+I D+
Sbjct: 3354 TVTSEGQPARFQCRVS-GTDLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDE 3411
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
+ VA N GQ ++ L L P R + ++
Sbjct: 3412 GTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIE 3449
Score = 51.6 bits (118), Expect = 4e-05
Identities = 72/300 (24%), Positives = 120/300 (40%), Gaps = 39/300 (13%)
Query: 92 PK-NYRKPRFMENL-QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------G 140
PK N P F+E L + + E + F +V G P P + W+++ L+P G
Sbjct: 5176 PKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVG 5235
Query: 141 DVYQLTGTNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK 196
+V L +N G Y C A N +G+A S A + DI Q L +Q
Sbjct: 5236 NVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV---DIMPQEERVVALPPPVTHQHVM 5292
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
+ ++ P ++V + + + + + V + + LD+
Sbjct: 5293 EFDLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPE--FTPDHKSMIVSLDVL 5350
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECK 315
F+D N + LK+ + PRF+ + E + +C
Sbjct: 5351 PFNFVDP--------NMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCS 5402
Query: 316 VIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVA 365
VIG+P P +KWYK+ ++P +I +IS + G+ +L TY C A NC+G A
Sbjct: 5403 VIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEA 5462
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/91 (32%), Positives = 51/91 (56%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQLTG 147
P F++ LQ++ +G V + +V G PTPV+ +++DG E++ GD+Y L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVE 174
+ G+Y A N +G+A+S+AEL V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 48.4 bits (110), Expect = 4e-04
Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 15/79 (18%)
Query: 111 EGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TGTNSL----------GSYC 155
EG+ V+F CK+ G+P P ++W+KDG+ +K G+ YQ+ G SL G Y
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1363
Query: 156 CIAKNCMGQASSSAELTVE 174
A N G A S +L VE
Sbjct: 1364 AFASNIKGNAICSGKLYVE 1382
Score = 47.6 bits (108), Expect = 7e-04
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P V GLK+V E ++ P P++ WYR+D ++ S + + G+ L
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQI-TFQSGIARLM 1001
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
I+ D + C A N+ G TSC+L + + ++K
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 1040
Score = 44.8 bits (101), Expect = 0.005
Identities = 34/110 (30%), Positives = 58/110 (52%), Gaps = 17/110 (15%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P + LQ +T EG + F+C+V G V SW+ +++KP D YQL
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNE--EEKLQLFSK 191
+ G+Y +A N +GQ SS+A L++E ++ L+E E+++++ K
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMK 3453
Score = 44.0 bits (99), Expect = 0.009
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 15/101 (14%)
Query: 98 PRFMENL--QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTN------ 149
P+ ++ + A E + EC + G P PV++WF++G LK +Q N
Sbjct: 4158 PKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLY 4217
Query: 150 -------SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEE 183
G Y C+A+N G S ++LTVE + + N +
Sbjct: 4218 IKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQ 4258
Score = 42.7 bits (96), Expect = 0.020
Identities = 56/221 (25%), Positives = 90/221 (40%), Gaps = 43/221 (19%)
Query: 96 RKPRFMENLQAV-LTEEGLVSFECKV--VGFPTPVLSWFKDGQELKPGD----------- 141
+KP F + L ++ L G FEC++ +G PT V+ W DG+ L+ +
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1760
Query: 142 --VYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEE------------EKLQ 187
Y + + G C A N G +SA L V+D ++ + E E+L+
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELE 1820
Query: 188 LFS-------------KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + Q P V + V E RF +V P+P + WY + Q
Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1880
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ +S R + + G+ +LDI + D E K A N G
Sbjct: 1881 IRKSKRFRVRYD--GIHYLDIVDCKSYDTGEVKVTAENPEG 1919
Score = 41.5 bits (93), Expect = 0.046
Identities = 75/340 (22%), Positives = 143/340 (42%), Gaps = 54/340 (15%)
Query: 73 EVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWF 131
+ +++ ++++ NS P+ P F++ +++ EG +F C G+P P+++W+
Sbjct: 3920 KTEQKEENMRFFENSFRKRPQRC-PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWY 3978
Query: 132 KDGQELKPG--------DVYQLTGTNSL-----GSYCCIAKNCMGQASSSAELTVE---- 174
+ + + Y + +S+ GS C+ N G +++ L V+
Sbjct: 3979 NNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQK 4038
Query: 175 -DIQ--------NQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP--E 223
D++ + L+EEE+L L +QA K H S E + + T +PP +
Sbjct: 4039 HDVKAHKVPVFHDYLDEEEELALVF-DQA-KGAHPSMSQEGQTNLHLLKT-NPPVPPSGD 4095
Query: 224 PSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
LL + + V ++ KE + VF + + E K + + QS F
Sbjct: 4096 TELLSFPVEIQVTAATPIPEQDKESKEVFQTE--------ELEPKAMPQDQVTQSPKHRF 4147
Query: 283 LKLIIPRHYKKPRFLENL--QAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD--- 337
+ L + + P+ L+ + A + ++ LEC + G PQPV+ W+++G LK
Sbjct: 4148 VFLSDITN-EPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQ 4206
Query: 338 ------IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
H++ + G Y C A N G S + L
Sbjct: 4207 FEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDL 4246
Score = 41.1 bits (92), Expect = 0.061
Identities = 28/136 (20%), Positives = 58/136 (42%), Gaps = 9/136 (6%)
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA-------PKFVHGLKSVEAKID 209
I K+ + + SA +++ + + +EE ++ F + P F+ ++S E
Sbjct: 3900 IKKDDLRELQLSASTRIDEFKTE-QKEENMRFFENSFRKRPQRCPPSFLQEIESQEVYEG 3958
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCV 269
+ F P+P + WY +D P+ + + E L + ++ ++ CV
Sbjct: 3959 DSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLE-NYSILTLSSVHHQNEGSITCV 4017
Query: 270 AFNDFGQSVTSCFLKL 285
FN +G T+ LK+
Sbjct: 4018 LFNQYGTVKTTSMLKV 4033
Score = 40.7 bits (91), Expect = 0.081
Identities = 24/105 (22%), Positives = 49/105 (46%)
Query: 181 NEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
++E K+ L P+F+ + + + F V P P + WY++ ++ +
Sbjct: 5366 DKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNI 5425
Query: 241 CHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
++ EE+G L I+ + D A ++C A N G+++ FL +
Sbjct: 5426 KYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTM 5470
Score = 40.3 bits (90), Expect = 0.11
Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 14/94 (14%)
Query: 292 KKPRFLENLQAI-LSDEGAVNLECKV--IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT 348
+KP F + L ++ L G + EC++ IG P V++W DG+ L+ + R+I+ + G
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN-EFGY 1759
Query: 349 CSL----------GTYTCEASNCMGVAASSASLL 372
CSL G TC A+N G +SA+L+
Sbjct: 1760 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1793
Score = 39.1 bits (87), Expect = 0.25
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGE---------ELKPGDIHRIIS 343
PRF++ + + G A +C V G P+P + WYKDG+ E H +
Sbjct: 5514 PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFI 5573
Query: 344 GQDGTCSLGTYTCEASNCMGVAASSASL 371
G Y C A+N G+A S A+L
Sbjct: 5574 TSLVKSDEGEYRCVATNKSGMAESFAAL 5601
Score = 38.7 bits (86), Expect = 0.33
Identities = 29/114 (25%), Positives = 46/114 (40%), Gaps = 3/114 (2%)
Query: 95 YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL-- 151
Y KP F + L EG V F C+++ PTP ++WF + + + G + + L
Sbjct: 3501 YFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHH 3560
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
S K + S S L + + L + K Q K++ LK E
Sbjct: 3561 HSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAE 3614
Score = 38.3 bits (85), Expect = 0.43
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P + L+ V EG V+ EC + G+P+P ++W+++ +++ +Q+T + +
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 152 --------GSYCCIAKNCMGQASSSAELTVE 174
G + C A N G S+S L V+
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Score = 37.9 bits (84), Expect = 0.57
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P + L+ + EG +V LEC + G P P + WY++ +++ I I+ Q G L
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITFQSGIARLM 1001
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G +TC A N G ++S L
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYL 1030
Score = 37.9 bits (84), Expect = 0.57
Identities = 35/160 (21%), Positives = 70/160 (43%), Gaps = 12/160 (7%)
Query: 90 TVPKNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT 148
T K +KP + + V EG + F C+V G+P P ++W+ +GQ ++ +++
Sbjct: 1833 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD 1892
Query: 149 NSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G + +C + ++T E+ + + + KL++ + +SV +
Sbjct: 1893 ---GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED-------FRSVLRRA 1942
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
EP R V P + + D+PVD + + K +R
Sbjct: 1943 PEP-RPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKR 1981
Score = 36.3 bits (80), Expect = 1.7
Identities = 41/148 (27%), Positives = 62/148 (41%), Gaps = 13/148 (8%)
Query: 238 SSRCHLGKEERGVFFLDIQAL-EFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
S+ C+L + F + A+ E E + V D + TS + P P F
Sbjct: 1025 STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1084
Query: 297 LEN-LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL--- 351
+ + L + G+V C+V G P+P + W K G L G +++ + Q G C L
Sbjct: 1085 ITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVIS 1144
Query: 352 -------GTYTCEASNCMGVAASSASLL 372
G YT N G ++SASLL
Sbjct: 1145 MTFADDAGEYTIVVRNKHGETSASASLL 1172
Score = 35.1 bits (77), Expect = 4.0
Identities = 59/259 (22%), Positives = 106/259 (40%), Gaps = 30/259 (11%)
Query: 90 TVPKNYRKPRFMENLQAV----LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
T K KPR + LQ + + E +V E KV + W KDGQE++P D +
Sbjct: 2345 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHI 2403
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
S+ + ++ + + + T+ + L+ ++ ++S + + LK V
Sbjct: 2404 VIDKQ--SHMLLIEDMTKEDAGNYSFTIPAL--GLSTSGRVSVYSVD----VITPLKDVN 2455
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL---GKEERGVFFLDIQALEFLD 262
KV++P S+ WY +D+ + R G ++R L I D
Sbjct: 2456 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQR----LVINRTHASD 2511
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQP 322
+ +K + G+ T+C L + K R L +L + +E G+
Sbjct: 2512 EGPYKLIV----GRVETNCNLSV---EKIKIIRGLRDLTCTETQNVVFEVELSHSGI--D 2562
Query: 323 VLKWYKDGEELKPGDIHRI 341
VL +KD +E+KP ++I
Sbjct: 2563 VLWNFKD-KEIKPSSKYKI 2580
Score = 35.1 bits (77), Expect = 4.0
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 22/228 (9%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC+V P W +DG+ L TN++ S K + A++ + E
Sbjct: 2639 FECEVAN-PDSKGEWLRDGKHLPL--------TNNIRSESDGHKRRLIIAATKLDDIGEY 2689
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+ +L K +A K LK++ + FT+++ P + W ++ V
Sbjct: 2690 TYKVATSKTSAKL--KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV-V 2746
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
ES+ + + ++ L I+ +D++ + F G+ S L + + KKP+
Sbjct: 2747 LESNEKYAISVKGTIYSLRIKNCAIVDESVY---GFR-LGRLGASARLHVETVKIIKKPK 2802
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
+ L+ V E V PV KW+ E+KP D HR++S
Sbjct: 2803 DVTALE-----NATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVS 2844
>AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein.
Length = 5604
Score = 77.0 bits (181), Expect = 1e-12
Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVF 251
QAP F L+SV F ++ P P + W+RD Q + S+ + G
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-V 310
L I A+ + + A N GQ+ ++ +L++ P F++ LQ++ +G+ V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTA--ELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 311 NLECKVIGVPQPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNC 361
L+ +V G+P PV+K+Y+DG E+ + GD++ ++ + GTY+ A+N
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 362 MGVAASSASLL 372
+G A S+A LL
Sbjct: 182 VGRATSTAELL 192
Score = 70.5 bits (165), Expect = 9e-11
Identities = 54/198 (27%), Positives = 91/198 (45%), Gaps = 22/198 (11%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+ + L+ V + +P RF ++ P+P + WY+++Q + +C + +
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK--------KPRFLENLQAIL 304
L I+A D A + C A ND+G + TS L + +P P + LQ +
Sbjct: 3297 LLIEAFP-EDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3355
Query: 305 SDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GT 353
+ EG +C+V G V WY +++KP R+ +D T L GT
Sbjct: 3356 TSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGT 3413
Query: 354 YTCEASNCMGVAASSASL 371
YT ASN +G +S+A+L
Sbjct: 3414 YTFVASNAVGQVSSTANL 3431
Score = 66.5 bits (155), Expect = 1e-09
Identities = 50/175 (28%), Positives = 77/175 (44%), Gaps = 3/175 (1%)
Query: 179 QLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDES 238
+L E ++ QL + P FV S + + RF +KV P P W+ D Q +
Sbjct: 1442 RLEETDESQL-ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVND 1500
Query: 239 SRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLE 298
+ +E G L I D EW VA N G+S S L + H KP F+E
Sbjct: 1501 YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560
Query: 299 NLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL 351
L+ + EG+ + ++ + G P P + W K+ + + P +I I G G +L
Sbjct: 1561 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL 1615
Score = 62.5 bits (145), Expect = 2e-08
Identities = 60/249 (24%), Positives = 106/249 (42%), Gaps = 13/249 (5%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSYC 155
P+ E +Q+ +G F +VVG P P W+K+G +++ D +Y +++
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE-- 2135
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
+ ++ + S+S + +I + + L L Q F L+ V AK +
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFL-LVQAKQLITFTQELQDVVAKEKDTMATF 2194
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
P + WY+D V E + + +R V FL I ++ D ++ CV D
Sbjct: 2195 ECETSEPFVKVKWYKDGMEVHEGDKYRM-HSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2253
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELK 334
T+ KLI+ + F++ LQ I + + + LEC ++ KWY + ELK
Sbjct: 2254 VKTTA---KLIVEGAVVE--FVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELK 2307
Query: 335 PGDIHRIIS 343
+ I S
Sbjct: 2308 SNGKYTITS 2316
Score = 60.5 bits (140), Expect = 9e-08
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 2/187 (1%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC 156
P F + LQ+V+ EG +FE + GFP P +SWF+DGQ + + + + S G
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
S L + Q +L + ++ P FV L+S+ + R +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+V P P + +YRD + S + +E ++ L I D + A N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQI-SQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 277 SVTSCFL 283
+ ++ L
Sbjct: 185 ATSTAEL 191
Score = 59.3 bits (137), Expect = 2e-07
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 6/162 (3%)
Query: 184 EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
+K++L +APK ++S F ++V P+P WY++ ++ S R +
Sbjct: 2067 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2126
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI 303
E V L I+ + D A A N G++ + FL + + + F + LQ +
Sbjct: 2127 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFL---LVQAKQLITFTQELQDV 2183
Query: 304 LSDE--GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
++ E EC+ P +KWYKDG E+ GD +R+ S
Sbjct: 2184 VAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHS 2224
Score = 59.3 bits (137), Expect = 2e-07
Identities = 61/225 (27%), Positives = 100/225 (44%), Gaps = 38/225 (16%)
Query: 98 PRF-MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLT---GTNSL- 151
PRF M + E F+C V+G PTP + W+K+ ++P ++ Y ++ G+++L
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQ-------------NQLNEEEKLQL- 188
+Y C A NC+G+A LT+ D + + L EE L+
Sbjct: 5440 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSN 5499
Query: 189 ----FSKNQA----PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
F + Q P+F+ G+ A I F V P P++ WY+D + V + R
Sbjct: 5500 YTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRR 5558
Query: 241 CHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ + G L I +L D+ E++CVA N G + + L L
Sbjct: 5559 FTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 58.4 bits (135), Expect = 4e-07
Identities = 70/255 (27%), Positives = 114/255 (44%), Gaps = 31/255 (12%)
Query: 100 FMENLQAVLTEEG--LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCI 157
F + LQ V+ +E + +FEC+ P + W+KDG E+ GD Y++ + + I
Sbjct: 2176 FTQELQDVVAKEKDTMATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKV-HFLSI 2233
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
A + + VED N + +L + +FV L+ +E + E + ++
Sbjct: 2234 LTIDTSDAEDYSCVLVEDE----NVKTTAKLIVEGAVVEFVKELQDIE--VPESYSGELE 2287
Query: 218 VAIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+ PE WY +D + + + + RG L ++ + DQ E+ V
Sbjct: 2288 CIVSPENIEGKWYHNDVELKSNGKYTI-TSRRGRQNLTVKDVTKEDQGEYSFV----IDG 2342
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSD----EG-AVNLECKVIGVPQPVLKWYKDGE 331
T+C LK+ KPR + LQ LSD EG V LE KV + W KDG+
Sbjct: 2343 KKTTCKLKM-------KPRPIAILQG-LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQ 2393
Query: 332 ELKPGD-IHRIISGQ 345
E++P D +H +I Q
Sbjct: 2394 EVQPSDRVHIVIDKQ 2408
Score = 58.0 bits (134), Expect = 5e-07
Identities = 84/302 (27%), Positives = 124/302 (41%), Gaps = 53/302 (17%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ---------------LTGTNSLG 152
L E G V F C+V G P P + W K G L G Y+ +T + G
Sbjct: 1093 LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAG 1152
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA------ 206
Y + +N G+ S+SA L +E+ +L + + ++ + Q FV K E
Sbjct: 1153 EYTIVVRNKHGETSASASL-LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVY 1211
Query: 207 ----KIDEPFRFTIKVAIPPEPSLL-WYRDDQPVDESS-RCHLGKE-ERGVFFLDIQALE 259
K E + I+ + + ++ Y +DQ SS L KE E + ++ L
Sbjct: 1212 SEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELL 1271
Query: 260 FLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D E V ++ ++V S F I K R LE + V CK+ G
Sbjct: 1272 EEDGEEKMAVDISE-SEAVESGFDSRI-----KNYRILEGM--------GVTFHCKMSGY 1317
Query: 320 PQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSA 369
P P + WYKDG+ +K G+ +++ QDG SL G YT ASN G A S
Sbjct: 1318 PLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSG 1377
Query: 370 SL 371
L
Sbjct: 1378 KL 1379
Score = 56.0 bits (129), Expect = 2e-06
Identities = 53/201 (26%), Positives = 84/201 (41%), Gaps = 29/201 (14%)
Query: 97 KPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLT----GTNSL 151
KP F+ + EG + F+ KVVG P P WF DGQ++ +++ GT SL
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 152 ----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGL 201
G + +A+N G++S S LTVE +++Q+ P FV L
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVK-------------PMFVEKL 1562
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKE-ERGVFFLDIQALEF 260
K+V K ++ P P ++W ++ + + E +G L I +
Sbjct: 1563 KNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVS 1622
Query: 261 LDQAEWKCVAFNDFGQSVTSC 281
D A + A N G+ T C
Sbjct: 1623 QDSAWYTATAINKAGRDTTRC 1643
Score = 54.0 bits (124), Expect = 8e-06
Identities = 53/218 (24%), Positives = 95/218 (43%), Gaps = 21/218 (9%)
Query: 98 PRFMENLQAVLTEEGLVSFECKVV-GFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ ++ LQ V + G + C V+ G P P +SW+K+ Q L G Y L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3298
Query: 148 TNSLGS----YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+ Y C AKN G A++SA L+VE + ++ ++++ ++ P + L+
Sbjct: 3299 IEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVY----PPAIITPLQD 3353
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+P RF +V+ + + WY D+ + + SR + + L+I D+
Sbjct: 3354 TVTSEGQPARFQCRVS-GTDLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDE 3411
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
+ VA N GQ ++ L L P R + ++
Sbjct: 3412 GTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIE 3449
Score = 51.6 bits (118), Expect = 4e-05
Identities = 72/300 (24%), Positives = 120/300 (40%), Gaps = 39/300 (13%)
Query: 92 PK-NYRKPRFMENL-QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------G 140
PK N P F+E L + + E + F +V G P P + W+++ L+P G
Sbjct: 5176 PKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVG 5235
Query: 141 DVYQLTGTNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK 196
+V L +N G Y C A N +G+A S A + DI Q L +Q
Sbjct: 5236 NVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV---DIMPQEERVVALPPPVTHQHVM 5292
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
+ ++ P ++V + + + + + V + + LD+
Sbjct: 5293 EFDLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPE--FTPDHKSMIVSLDVL 5350
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECK 315
F+D N + LK+ + PRF+ + E + +C
Sbjct: 5351 PFNFVDP--------NMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCS 5402
Query: 316 VIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVA 365
VIG+P P +KWYK+ ++P +I +IS + G+ +L TY C A NC+G A
Sbjct: 5403 VIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEA 5462
Score = 49.6 bits (113), Expect = 2e-04
Identities = 30/91 (32%), Positives = 51/91 (56%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQLTG 147
P F++ LQ++ +G V + +V G PTPV+ +++DG E++ GD+Y L
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVE 174
+ G+Y A N +G+A+S+AEL V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 48.4 bits (110), Expect = 4e-04
Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 15/79 (18%)
Query: 111 EGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL----TGTNSL----------GSYC 155
EG+ V+F CK+ G+P P ++W+KDG+ +K G+ YQ+ G SL G Y
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1363
Query: 156 CIAKNCMGQASSSAELTVE 174
A N G A S +L VE
Sbjct: 1364 AFASNIKGNAICSGKLYVE 1382
Score = 47.6 bits (108), Expect = 7e-04
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P V GLK+V E ++ P P++ WYR+D ++ S + + G+ L
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQI-TFQSGIARLM 1001
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
I+ D + C A N+ G TSC+L + + ++K
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEK 1040
Score = 44.8 bits (101), Expect = 0.005
Identities = 34/110 (30%), Positives = 58/110 (52%), Gaps = 17/110 (15%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P + LQ +T EG + F+C+V G V SW+ +++KP D YQL
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNE--EEKLQLFSK 191
+ G+Y +A N +GQ SS+A L++E ++ L+E E+++++ K
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMK 3453
Score = 44.0 bits (99), Expect = 0.009
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 15/101 (14%)
Query: 98 PRFMENL--QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTN------ 149
P+ ++ + A E + EC + G P PV++WF++G LK +Q N
Sbjct: 4158 PKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLY 4217
Query: 150 -------SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEE 183
G Y C+A+N G S ++LTVE + + N +
Sbjct: 4218 IKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQ 4258
Score = 42.7 bits (96), Expect = 0.020
Identities = 56/221 (25%), Positives = 90/221 (40%), Gaps = 43/221 (19%)
Query: 96 RKPRFMENLQAV-LTEEGLVSFECKV--VGFPTPVLSWFKDGQELKPGD----------- 141
+KP F + L ++ L G FEC++ +G PT V+ W DG+ L+ +
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1760
Query: 142 --VYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEE------------EKLQ 187
Y + + G C A N G +SA L V+D ++ + E E+L+
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELE 1820
Query: 188 LFS-------------KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ + Q P V + V E RF +V P+P + WY + Q
Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1880
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ +S R + + G+ +LDI + D E K A N G
Sbjct: 1881 IRKSKRFRVRYD--GIHYLDIVDCKSYDTGEVKVTAENPEG 1919
Score = 41.5 bits (93), Expect = 0.046
Identities = 75/340 (22%), Positives = 143/340 (42%), Gaps = 54/340 (15%)
Query: 73 EVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWF 131
+ +++ ++++ NS P+ P F++ +++ EG +F C G+P P+++W+
Sbjct: 3920 KTEQKEENMRFFENSFRKRPQRC-PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWY 3978
Query: 132 KDGQELKPG--------DVYQLTGTNSL-----GSYCCIAKNCMGQASSSAELTVE---- 174
+ + + Y + +S+ GS C+ N G +++ L V+
Sbjct: 3979 NNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQK 4038
Query: 175 -DIQ--------NQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP--E 223
D++ + L+EEE+L L +QA K H S E + + T +PP +
Sbjct: 4039 HDVKAHKVPVFHDYLDEEEELALVF-DQA-KGAHPSMSQEGQTNLHLLKT-NPPVPPSGD 4095
Query: 224 PSLLWYRDDQPVDESSRC-HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
LL + + V ++ KE + VF + + E K + + QS F
Sbjct: 4096 TELLSFPVEIQVTAATPIPEQDKESKEVFQTE--------ELEPKAMPQDQVTQSPKHRF 4147
Query: 283 LKLIIPRHYKKPRFLENL--QAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD--- 337
+ L + + P+ L+ + A + ++ LEC + G PQPV+ W+++G LK
Sbjct: 4148 VFLSDITN-EPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQ 4206
Query: 338 ------IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
H++ + G Y C A N G S + L
Sbjct: 4207 FEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDL 4246
Score = 41.1 bits (92), Expect = 0.061
Identities = 28/136 (20%), Positives = 58/136 (42%), Gaps = 9/136 (6%)
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA-------PKFVHGLKSVEAKID 209
I K+ + + SA +++ + + +EE ++ F + P F+ ++S E
Sbjct: 3900 IKKDDLRELQLSASTRIDEFKTE-QKEENMRFFENSFRKRPQRCPPSFLQEIESQEVYEG 3958
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCV 269
+ F P+P + WY +D P+ + + E L + ++ ++ CV
Sbjct: 3959 DSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLE-NYSILTLSSVHHQNEGSITCV 4017
Query: 270 AFNDFGQSVTSCFLKL 285
FN +G T+ LK+
Sbjct: 4018 LFNQYGTVKTTSMLKV 4033
Score = 40.7 bits (91), Expect = 0.081
Identities = 24/105 (22%), Positives = 49/105 (46%)
Query: 181 NEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
++E K+ L P+F+ + + + F V P P + WY++ ++ +
Sbjct: 5366 DKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNI 5425
Query: 241 CHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
++ EE+G L I+ + D A ++C A N G+++ FL +
Sbjct: 5426 KYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTM 5470
Score = 40.3 bits (90), Expect = 0.11
Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 14/94 (14%)
Query: 292 KKPRFLENLQAI-LSDEGAVNLECKV--IGVPQPVLKWYKDGEELKPGDIHRIISGQDGT 348
+KP F + L ++ L G + EC++ IG P V++W DG+ L+ + R+I+ + G
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN-EFGY 1759
Query: 349 CSL----------GTYTCEASNCMGVAASSASLL 372
CSL G TC A+N G +SA+L+
Sbjct: 1760 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1793
Score = 39.1 bits (87), Expect = 0.25
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGE---------ELKPGDIHRIIS 343
PRF++ + + G A +C V G P+P + WYKDG+ E H +
Sbjct: 5514 PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFI 5573
Query: 344 GQDGTCSLGTYTCEASNCMGVAASSASL 371
G Y C A+N G+A S A+L
Sbjct: 5574 TSLVKSDEGEYRCVATNKSGMAESFAAL 5601
Score = 38.7 bits (86), Expect = 0.33
Identities = 29/114 (25%), Positives = 46/114 (40%), Gaps = 3/114 (2%)
Query: 95 YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL-- 151
Y KP F + L EG V F C+++ PTP ++WF + + + G + + L
Sbjct: 3501 YFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHH 3560
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
S K + S S L + + L + K Q K++ LK E
Sbjct: 3561 HSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAE 3614
Score = 38.3 bits (85), Expect = 0.43
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P + L+ V EG V+ EC + G+P+P ++W+++ +++ +Q+T + +
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 152 --------GSYCCIAKNCMGQASSSAELTVE 174
G + C A N G S+S L V+
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Score = 37.9 bits (84), Expect = 0.57
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 12/89 (13%)
Query: 294 PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL- 351
P + L+ + EG +V LEC + G P P + WY++ +++ I I+ Q G L
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITFQSGIARLM 1001
Query: 352 ---------GTYTCEASNCMGVAASSASL 371
G +TC A N G ++S L
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYL 1030
Score = 37.9 bits (84), Expect = 0.57
Identities = 35/160 (21%), Positives = 70/160 (43%), Gaps = 12/160 (7%)
Query: 90 TVPKNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGT 148
T K +KP + + V EG + F C+V G+P P ++W+ +GQ ++ +++
Sbjct: 1833 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD 1892
Query: 149 NSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G + +C + ++T E+ + + + KL++ + +SV +
Sbjct: 1893 ---GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED-------FRSVLRRA 1942
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER 248
EP R V P + + D+PVD + + K +R
Sbjct: 1943 PEP-RPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKR 1981
Score = 36.3 bits (80), Expect = 1.7
Identities = 41/148 (27%), Positives = 62/148 (41%), Gaps = 13/148 (8%)
Query: 238 SSRCHLGKEERGVFFLDIQAL-EFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
S+ C+L + F + A+ E E + V D + TS + P P F
Sbjct: 1025 STSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYF 1084
Query: 297 LEN-LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI-ISGQDGTCSL--- 351
+ + L + G+V C+V G P+P + W K G L G +++ + Q G C L
Sbjct: 1085 ITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVIS 1144
Query: 352 -------GTYTCEASNCMGVAASSASLL 372
G YT N G ++SASLL
Sbjct: 1145 MTFADDAGEYTIVVRNKHGETSASASLL 1172
Score = 35.1 bits (77), Expect = 4.0
Identities = 59/259 (22%), Positives = 106/259 (40%), Gaps = 30/259 (11%)
Query: 90 TVPKNYRKPRFMENLQAV----LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
T K KPR + LQ + + E +V E KV + W KDGQE++P D +
Sbjct: 2345 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHI 2403
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
S+ + ++ + + + T+ + L+ ++ ++S + + LK V
Sbjct: 2404 VIDKQ--SHMLLIEDMTKEDAGNYSFTIPAL--GLSTSGRVSVYSVD----VITPLKDVN 2455
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL---GKEERGVFFLDIQALEFLD 262
KV++P S+ WY +D+ + R G ++R L I D
Sbjct: 2456 VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQR----LVINRTHASD 2511
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQP 322
+ +K + G+ T+C L + K R L +L + +E G+
Sbjct: 2512 EGPYKLIV----GRVETNCNLSV---EKIKIIRGLRDLTCTETQNVVFEVELSHSGI--D 2562
Query: 323 VLKWYKDGEELKPGDIHRI 341
VL +KD +E+KP ++I
Sbjct: 2563 VLWNFKD-KEIKPSSKYKI 2580
Score = 35.1 bits (77), Expect = 4.0
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 22/228 (9%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC+V P W +DG+ L TN++ S K + A++ + E
Sbjct: 2639 FECEVAN-PDSKGEWLRDGKHLPL--------TNNIRSESDGHKRRLIIAATKLDDIGEY 2689
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+ +L K +A K LK++ + FT+++ P + W ++ V
Sbjct: 2690 TYKVATSKTSAKL--KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV-V 2746
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
ES+ + + ++ L I+ +D++ + F G+ S L + + KKP+
Sbjct: 2747 LESNEKYAISVKGTIYSLRIKNCAIVDESVY---GFR-LGRLGASARLHVETVKIIKKPK 2802
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
+ L+ V E V PV KW+ E+KP D HR++S
Sbjct: 2803 DVTALE-----NATVAFEVSVSHDTVPV-KWFHKSVEIKPSDKHRLVS 2844
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 76.6 bits (180), Expect = 1e-12
Identities = 85/306 (27%), Positives = 129/306 (42%), Gaps = 35/306 (11%)
Query: 86 NSHPTVPKNYRKPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG---- 140
+S P + +P F+ + V+ EE V F C+V G P P + W KD +L G
Sbjct: 213 DSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDI 272
Query: 141 -DVYQL----TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
D Y L T + G+Y CIA+N +G+ +SA LTV Q + Q+ ++ +
Sbjct: 273 KDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVR-APPQFVVRPRDQIVAQGRTV 331
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDI 255
F K +P F K +LL+ +QP +SRC + L I
Sbjct: 332 TFPCETKGNP----QPAVFWQKEG---SQNLLF--PNQPQQPNSRCSVSPTGD----LTI 378
Query: 256 QALEFLDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLEN-LQAILSDEGAVNLE 313
++ D + C A G + L++ + P L+ L+ +G L+
Sbjct: 379 TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLK 438
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVA 365
CK G P PV+ W K+G PG R + GT + GTYTC A++ G
Sbjct: 439 CKATGDPLPVISWLKEGFTF-PGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGET 497
Query: 366 ASSASL 371
+ SA L
Sbjct: 498 SWSAVL 503
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/305 (26%), Positives = 131/305 (42%), Gaps = 58/305 (19%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELK-----PGDVYQLTGTNSL 151
PR +E+ V+ +G + CK G PTP + W+KDG+ ++ P L + SL
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90
Query: 152 ---------------GSYCCIAKNCMGQA-SSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
GSY C+A+N +G+A S +A L V +++ F +N
Sbjct: 91 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDD---------FRQNPTD 141
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF--- 252
V + + P PEP++ W +D +D+ KEER
Sbjct: 142 VVVAAGEPAILECQPPRGH-------PEPTIYWKKDKVRIDD-------KEERISIRGGK 187
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN-LQAILSDEGAVN 311
L I D + CV N G+ S +L + +++P FL + ++ +E AV
Sbjct: 188 LMISNTRKSDAGMYTCVGTNMVGER-DSDPAELTV---FERPTFLRRPINQVVLEEEAVE 243
Query: 312 LECKVIGVPQPVLKWYKDGEELKPG-----DIHRIISGQDGTCSLGTYTCEASNCMGVAA 366
C+V G PQP ++W KD +L G D + + + + GTY C A N +G
Sbjct: 244 FRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKME 303
Query: 367 SSASL 371
+SA+L
Sbjct: 304 ASATL 308
Score = 40.7 bits (91), Expect = 0.081
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 11/79 (13%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---KPGDVYQLTGT--------NSLGSYCC 156
L +G +CK G P PV+SW K+G P Q GT + G+Y C
Sbjct: 429 LAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTC 488
Query: 157 IAKNCMGQASSSAELTVED 175
+A + G+ S SA L V +
Sbjct: 489 VATSSSGETSWSAVLDVTE 507
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 76.6 bits (180), Expect = 1e-12
Identities = 85/306 (27%), Positives = 129/306 (42%), Gaps = 35/306 (11%)
Query: 86 NSHPTVPKNYRKPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG---- 140
+S P + +P F+ + V+ EE V F C+V G P P + W KD +L G
Sbjct: 229 DSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDI 288
Query: 141 -DVYQL----TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
D Y L T + G+Y CIA+N +G+ +SA LTV Q + Q+ ++ +
Sbjct: 289 KDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVR-APPQFVVRPRDQIVAQGRTV 347
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDI 255
F K +P F K +LL+ +QP +SRC + L I
Sbjct: 348 TFPCETKGNP----QPAVFWQKEG---SQNLLF--PNQPQQPNSRCSVSPTGD----LTI 394
Query: 256 QALEFLDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLEN-LQAILSDEGAVNLE 313
++ D + C A G + L++ + P L+ L+ +G L+
Sbjct: 395 TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLK 454
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVA 365
CK G P PV+ W K+G PG R + GT + GTYTC A++ G
Sbjct: 455 CKATGDPLPVISWLKEGFTF-PGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGET 513
Query: 366 ASSASL 371
+ SA L
Sbjct: 514 SWSAVL 519
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/305 (26%), Positives = 131/305 (42%), Gaps = 58/305 (19%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELK-----PGDVYQLTGTNSL 151
PR +E+ V+ +G + CK G PTP + W+KDG+ ++ P L + SL
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 106
Query: 152 ---------------GSYCCIAKNCMGQA-SSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
GSY C+A+N +G+A S +A L V +++ F +N
Sbjct: 107 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDD---------FRQNPTD 157
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF--- 252
V + + P PEP++ W +D +D+ KEER
Sbjct: 158 VVVAAGEPAILECQPPRGH-------PEPTIYWKKDKVRIDD-------KEERISIRGGK 203
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN-LQAILSDEGAVN 311
L I D + CV N G+ S +L + +++P FL + ++ +E AV
Sbjct: 204 LMISNTRKSDAGMYTCVGTNMVGER-DSDPAELTV---FERPTFLRRPINQVVLEEEAVE 259
Query: 312 LECKVIGVPQPVLKWYKDGEELKPG-----DIHRIISGQDGTCSLGTYTCEASNCMGVAA 366
C+V G PQP ++W KD +L G D + + + + GTY C A N +G
Sbjct: 260 FRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKME 319
Query: 367 SSASL 371
+SA+L
Sbjct: 320 ASATL 324
Score = 40.7 bits (91), Expect = 0.081
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 11/79 (13%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---KPGDVYQLTGT--------NSLGSYCC 156
L +G +CK G P PV+SW K+G P Q GT + G+Y C
Sbjct: 445 LAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTC 504
Query: 157 IAKNCMGQASSSAELTVED 175
+A + G+ S SA L V +
Sbjct: 505 VATSSSGETSWSAVLDVTE 523
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 76.6 bits (180), Expect = 1e-12
Identities = 85/306 (27%), Positives = 129/306 (42%), Gaps = 35/306 (11%)
Query: 86 NSHPTVPKNYRKPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG---- 140
+S P + +P F+ + V+ EE V F C+V G P P + W KD +L G
Sbjct: 215 DSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDI 274
Query: 141 -DVYQL----TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
D Y L T + G+Y CIA+N +G+ +SA LTV Q + Q+ ++ +
Sbjct: 275 KDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVR-APPQFVVRPRDQIVAQGRTV 333
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDI 255
F K +P F K +LL+ +QP +SRC + L I
Sbjct: 334 TFPCETKGNP----QPAVFWQKEG---SQNLLF--PNQPQQPNSRCSVSPTGD----LTI 380
Query: 256 QALEFLDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLEN-LQAILSDEGAVNLE 313
++ D + C A G + L++ + P L+ L+ +G L+
Sbjct: 381 TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLK 440
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVA 365
CK G P PV+ W K+G PG R + GT + GTYTC A++ G
Sbjct: 441 CKATGDPLPVISWLKEGFTF-PGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGET 499
Query: 366 ASSASL 371
+ SA L
Sbjct: 500 SWSAVL 505
Score = 71.7 bits (168), Expect = 4e-11
Identities = 82/305 (26%), Positives = 131/305 (42%), Gaps = 58/305 (19%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELK-----PGDVYQLTGTNSL 151
PR +E+ V+ +G + CK G PTP + W+KDG+ ++ P L + SL
Sbjct: 33 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 92
Query: 152 ---------------GSYCCIAKNCMGQA-SSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
GSY C+A+N +G+A S +A L V +++ F +N
Sbjct: 93 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDD---------FRQNPTD 143
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF--- 252
V + + P PEP++ W +D +D+ KEER
Sbjct: 144 VVVAAGEPAILECQPPRGH-------PEPTIYWKKDKVRIDD-------KEERISIRGGK 189
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN-LQAILSDEGAVN 311
L I D + CV N G+ S +L + +++P FL + ++ +E AV
Sbjct: 190 LMISNTRKSDAGMYTCVGTNMVGER-DSDPAELTV---FERPTFLRRPINQVVLEEEAVE 245
Query: 312 LECKVIGVPQPVLKWYKDGEELKPG-----DIHRIISGQDGTCSLGTYTCEASNCMGVAA 366
C+V G PQP ++W KD +L G D + + + + GTY C A N +G
Sbjct: 246 FRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKME 305
Query: 367 SSASL 371
+SA+L
Sbjct: 306 ASATL 310
Score = 40.7 bits (91), Expect = 0.081
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 11/79 (13%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---KPGDVYQLTGT--------NSLGSYCC 156
L +G +CK G P PV+SW K+G P Q GT + G+Y C
Sbjct: 431 LAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTC 490
Query: 157 IAKNCMGQASSSAELTVED 175
+A + G+ S SA L V +
Sbjct: 491 VATSSSGETSWSAVLDVTE 509
>AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine
phosphatase, receptor type, D isoform 4 precursor
variant protein.
Length = 1478
Score = 75.8 bits (178), Expect = 2e-12
Identities = 66/276 (23%), Positives = 118/276 (42%), Gaps = 16/276 (5%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 15 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 74
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 75 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 134
Query: 228 WYRDDQPVDESSRCHLGKEER--GVFF---LDIQALEFLDQAEWKCVAFNDFG---QSVT 279
W++D PVD S+ K+ R G L I+ E DQ +++CVA N G +
Sbjct: 135 WFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPA 194
Query: 280 SCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD- 337
+ +++ + PRF + + G+VN+ C +G P P +KW E+L P D
Sbjct: 195 NLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDD 254
Query: 338 --IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
I R + + YTC A + +GV + A +
Sbjct: 255 MPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 290
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 224 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 283
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 284 IEAIAQITVK 293
>AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 812
Score = 75.4 bits (177), Expect = 3e-12
Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 15/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C V G LSW+++G+ L PG ++TG N I + + + + V
Sbjct: 161 VSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN---LIMDHMVKSDGGAYQCFV 217
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+++L+ ++ +Q+ ++ PK + EP V P P++ W DD
Sbjct: 218 R--KDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD 275
Query: 234 PVDESSRCHLGK----EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ + + + E V +L+I + + D ++C A N G + + + P
Sbjct: 276 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 335
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R ++N+ AI + + C+VIG P +KWYK+ L P + ++ +GT
Sbjct: 336 SI---RPMKNITAIAGRD--TYIHCRVIGYPYYSIKWYKN-SNLLPFNHRQVAFENNGTL 389
Query: 350 SL 351
L
Sbjct: 390 KL 391
Score = 54.0 bits (124), Expect = 8e-06
Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVF 251
N AP + G +A + K PEP W +D+ P++ S G+ ++ V
Sbjct: 52 NSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELS-----GRFQKTVT 106
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP-RFLENLQAILSDEGA- 309
L I+ + D + C N +G + K+I + K+P + + + + S G+
Sbjct: 107 GLLIENIRPSDSGSYVCEVSNRYGTA------KVIGRLYVKQPLKATISPRKVKSSVGSQ 160
Query: 310 VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
V+L C V G L WY++GE L PG RI
Sbjct: 161 VSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 192
Score = 47.6 bits (108), Expect = 7e-04
Identities = 56/273 (20%), Positives = 99/273 (36%), Gaps = 30/273 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V CK +G P P W KD L+ +Q T T L +N S S V
Sbjct: 72 VELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLL------IENIRPSDSGS---YV 122
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
++ N+ + + Q K + V++ + + V + L WYR+ +
Sbjct: 123 CEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGE 182
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
++ + +D D ++C D + ++++++
Sbjct: 183 ILNPGKNVRITGINHENLIMDHMVKS--DGGAYQCFVRKD--KLSAQDYVQVVL--EDGT 236
Query: 294 PRFLENL-QAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI---ISGQDGTC 349
P+ + + ++S V+L C V G P P + W D + + G HRI I+ +
Sbjct: 237 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 296
Query: 350 SL-----------GTYTCEASNCMGVAASSASL 371
S G Y C A+N GV A +
Sbjct: 297 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 329
Score = 37.9 bits (84), Expect = 0.57
Identities = 49/233 (21%), Positives = 92/233 (39%), Gaps = 22/233 (9%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
R M+N+ A+ + + C+V+G+P + W+K+ L P + Q+ N+
Sbjct: 338 RPMKNITAIAGRDTYI--HCRVIGYPYYSIKWYKNSN-LLPFNHRQVAFENNGTLKLSDV 394
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ + + + + V Q QL+ + + + K P F+ + I + V
Sbjct: 395 QKEVDEGEYTCNVLV---QPQLSTSQSVHVTVK--VPPFIQPFEFPRFSIGQRVFIPCVV 449
Query: 219 AIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFF---LDIQALEFLDQAEWKCVAFNDF 274
P ++ W +D +P+ S LG + F L I L + + C+A N+
Sbjct: 450 VSGDLPITITWQKDGRPIPGS----LGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEA 505
Query: 275 GQ-SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
S + + P+ +PR + + AV L C G P P + W
Sbjct: 506 AAVEHQSQLIVRVPPKFVVQPRDQDGIYG-----KAVILNCSAEGYPVPTIVW 553
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 75.4 bits (177), Expect = 3e-12
Identities = 77/284 (27%), Positives = 120/284 (42%), Gaps = 42/284 (14%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELK--------PGD-VYQL--TGTNS 150
ENL V+ +S C+V GFP P LSW K+ Q +K PG Q+ +
Sbjct: 10 ENLTVVVNN--FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSD 67
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G Y CIA N G++ LTV + + + + L N V SV + +
Sbjct: 68 GGEYTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVN-----VREGTSVSLEXES 121
Query: 211 PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
A+PP P + WY++ + + ES+ + + + L I+ E D ++ C A
Sbjct: 122 N-------AVPP-PVITWYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRA 170
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G+ + L + +P + P E + + V L C G+P P + W K+
Sbjct: 171 INVAGRDDKNFHLNVYVPPSIEGP---EREVIVETISNPVTLTCDATGIPPPTIAWLKNH 227
Query: 331 EELKPGDIH--RIISG-------QDGTCSLGTYTCEASNCMGVA 365
+ ++ D RI+SG + G YTC ASN G A
Sbjct: 228 KRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 271
Score = 73.3 bits (172), Expect = 1e-11
Identities = 63/274 (22%), Positives = 111/274 (40%), Gaps = 23/274 (8%)
Query: 102 ENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKN 160
E+L V EG VS E + P PV++W+K+G+ + ++ G I K
Sbjct: 102 ESLSVVNVREGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEILAD---GQMLHIKK- 157
Query: 161 CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS--VEAKIDEPFRFTIKV 218
+ S + + I +++ L P + G + + I P T
Sbjct: 158 --AEVSDTGQYVCRAINVAGRDDKNFHL--NVYVPPSIEGPEREVIVETISNPVTLTCDA 213
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P++ W ++ + ++ S + + G L I + D + C+A N G++
Sbjct: 214 TGIPPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 272
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDI 338
FL + +P ++ +L + V L C G+P P+++W KDG+ + G+
Sbjct: 273 KYYFLSIQVPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGET 330
Query: 339 HRIISGQDG---------TCSLGTYTCEASNCMG 363
RI +G T G YTC A+N G
Sbjct: 331 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 364
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/268 (26%), Positives = 108/268 (40%), Gaps = 41/268 (15%)
Query: 115 SFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL--TGTNSLGSYCCIAKNCMG 163
S C G P P ++W +DGQ L G V QL T G Y CIA N G
Sbjct: 492 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 551
Query: 164 QASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
+ S L V + + EE + + ++ P T + P
Sbjct: 552 EVSKHFILKVLEPPHINGSEEH----------------EEISVIVNNPLELTCIASGIPA 595
Query: 224 PSLLWYRDDQPVDESSRCH-LGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
P + W +D +P+ ++ + LG E L I + D + C+A + G
Sbjct: 596 PKMTWMKDGRPLPQTDQVQTLGGGE----VLRISTAQVEDTGRYTCLASSPAGDDDKEYL 651
Query: 283 LKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
+++ +P + ++ + + + V LECK VP PV+ W ++GE L+ RI+
Sbjct: 652 VRVHVPPNIAGTDEPRDITVLRNRQ--VTLECKSDAVPPPVITWLRNGERLQATPRVRIL 709
Query: 343 SG----QDGTCSLG---TYTCEASNCMG 363
SG Q LG YTC ASN G
Sbjct: 710 SGGRYLQINNADLGDTANYTCVASNIAG 737
Score = 68.9 bits (161), Expect = 3e-10
Identities = 70/282 (24%), Positives = 111/282 (39%), Gaps = 42/282 (14%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQL----------TGTNSLGSYC 155
++T+ C G P P + W K+G L P GD Y++ T N G Y
Sbjct: 945 LVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYT 1004
Query: 156 CIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFT 215
C+A+N G A L V +E +Q P +H + ++ P
Sbjct: 1005 CVARNAAGSAHRHVTLHV-------HEPPVIQ-----PQPSELHVI------LNNPILLP 1046
Query: 216 IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
+ P P + W ++ V+ S R H G L I D + CVA N G
Sbjct: 1047 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMCVAQNPAG 1103
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
++ L + +P P E + A+ + + L C+ G+P P + W+KDG +
Sbjct: 1104 TALGKIKLNVQVPPVIS-PHLKEYVIAV---DKPITLSCEADGLPPPDITWHKDGRAIVE 1159
Query: 336 GDIHRIISGQDGTCSL------GTYTCEASNCMGVAASSASL 371
R++S + G YTC A+N G +++S L
Sbjct: 1160 SIRQRVLSSGSLQITFVQPGDAGHYTCMAANVAGSSSTSTKL 1201
Score = 67.7 bits (158), Expect = 6e-10
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ C G P P ++W K+ + ++ D ++ + GS IA++ Q S S T
Sbjct: 207 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG-GSKLQIARS---QHSDSGNYTC 262
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLK---SVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
I + + + + F Q P V G + V + E P P + W +
Sbjct: 263 --IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLK 320
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII-PR 289
D +P+ + G L+I D ++ CVA N G+ L + + P
Sbjct: 321 DGKPIASGETERIRVSANGST-LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT 379
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG---------EELKPGDIHR 340
E L ++ + ++N+EC+ G P P + W K+G L G + R
Sbjct: 380 IRGNKDEAEKLMTLV--DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIR 437
Query: 341 IISGQDGTCSLGTYTCEASNCMGV 364
I+ Q + YTC ASN GV
Sbjct: 438 IVRAQ--VSDVAVYTCVASNRAGV 459
Score = 62.5 bits (145), Expect = 2e-08
Identities = 67/285 (23%), Positives = 109/285 (38%), Gaps = 26/285 (9%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + ++ +L E V C G PTP++ W KDG+ + G+ ++ ++
Sbjct: 281 VPPSVAGAEIPSDVSVLLGEN--VELVCNANGIPTPLIQWLKDGKPIASGETERIR-VSA 337
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAK--- 207
GS N G +S N EE+++ + P + G K K
Sbjct: 338 NGS----TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IRGNKDEAEKLMT 392
Query: 208 -IDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+D + P P + W ++ P+ SS H+ G ++A + D A +
Sbjct: 393 LVDTSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVIRIVRA-QVSDVAVY 449
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
CVA N G L++ P + E + + + ++ C G P P + W
Sbjct: 450 TCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGS--STSMACITDGTPAPSMAW 507
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
+DG+ L D H +S L G YTC ASN G
Sbjct: 508 LRDGQPLGL-DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 551
Score = 58.0 bits (134), Expect = 5e-07
Identities = 64/256 (25%), Positives = 103/256 (40%), Gaps = 25/256 (9%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV-EDI 176
C G P P ++W KDG+ L D Q G + G+ + A +D
Sbjct: 588 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDD 647
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ L + P+ + L++ + ++ A+PP P + W R+ + +
Sbjct: 648 KEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE-----CKSDAVPP-PVITWLRNGERLQ 701
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PR 295
+ R + R +L I + D A + CVA N G++ L + +P + K P+
Sbjct: 702 ATPRVRILSGGR---YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ 758
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
L IL ++ V LEC GVP P + W KDG L G+ R ++G
Sbjct: 759 SL----VILLNKSTV-LECIAEGVPTPRITWRKDGAVL-AGNHARYSILENGFLHIQSAH 812
Query: 348 TCSLGTYTCEASNCMG 363
G Y C A+N G
Sbjct: 813 VTDTGRYLCMATNAAG 828
Score = 55.6 bits (128), Expect = 3e-06
Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 14/179 (7%)
Query: 195 PKFVHGLKS--VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
P V G KS + ++ T +V+ P P L W +++QP+ ++ + R
Sbjct: 1 PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT--- 57
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVN 311
L I + D E+ C+A N G+S L + +P K E+L + EG +V+
Sbjct: 58 LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSI-KDHDSESLSVVNVREGTSVS 116
Query: 312 LECKVIGVPQPVLKWYKDGEEL-KPGDIHRIISGQ------DGTCSLGTYTCEASNCMG 363
LE + VP PV+ WYK+G + + + + GQ G Y C A N G
Sbjct: 117 LEXESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 175
Score = 55.2 bits (127), Expect = 4e-06
Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 46/273 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELK---------PGDVYQLTGT--NSLGSYCCIAKNCMGQAS 166
C+ G P+P ++W K+G + P Q++ G+Y C+A+N G A
Sbjct: 1047 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTAL 1106
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+L V+ P LK +D+P + + P P +
Sbjct: 1107 GKIKLNVQ------------------VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI 1148
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W++D + + ES R + L I ++ D + C+A N G S TS L +
Sbjct: 1149 TWHKDGRAIVESIRQRVLSSGS----LQITFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 1204
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD 346
+P + R E + + A+ L C G+P P + W KD L + + +
Sbjct: 1205 VP---PRIRSTEGHYTVNENSQAI-LPCVADGIPTPAINWKKD-NVLLANLLGKYTAEPY 1259
Query: 347 GTCSL--------GTYTCEASNCMGVAASSASL 371
G L G YTC A+N G + SL
Sbjct: 1260 GELILENVVLEDSGFYTCVANNAAGEDTHTVSL 1292
Score = 52.8 bits (121), Expect = 2e-05
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 14/220 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V+ ECK P PV++W ++G+ L+ ++ S G Y I +G ++
Sbjct: 677 VTLECKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYT-CVA 732
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+I + E L + N P G +S+ +++ P P + W R D
Sbjct: 733 SNIAGKTTREFILTV---NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW-RKDG 788
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
V + E G FL IQ+ D + C+A N G L++ +P
Sbjct: 789 AVLAGNHARYSILENG--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAP 846
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
N+ I++ + L C+ G+P+P + W K+G L
Sbjct: 847 GP--TNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLL 882
Score = 46.8 bits (106), Expect = 0.001
Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 48/276 (17%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCC 156
V+ + ++ C+ G P P ++W KDG+ + ++ + SL G Y C
Sbjct: 1127 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQITFVQPGDAGHYTC 1186
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA--PKFVHGLKSVEAKIDEPFRF 214
+A N G +S+S +LTV + E + +QA P G+
Sbjct: 1187 MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI------------- 1233
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P++ W +D+ + + E G L+ LE D + CVA N
Sbjct: 1234 -------PTPAINWKKDNVLLANLLGKYTA-EPYGELILENVVLE--DSGFYTCVANNAA 1283
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
G+ + L + + P F E + ++G + L CK G+P P L W + +
Sbjct: 1284 GEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 1338
Query: 334 KP------GDIHRIISGQDGTCSLGTYTCEASNCMG 363
G +I S GTY C A N +G
Sbjct: 1339 PAHFDSVNGHSELVIERVSKEDS-GTYVCTAENSVG 1373
Score = 46.0 bits (104), Expect = 0.002
Identities = 67/283 (23%), Positives = 104/283 (36%), Gaps = 47/283 (16%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---------KP-GD-VYQLTGTNSLGSYCC 156
+ E C G PTP ++W KD L +P G+ + + G Y C
Sbjct: 1218 VNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTC 1277
Query: 157 IAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+A N G+ + + LTV + P F V E R +
Sbjct: 1278 VANNAAGEDTHTVSLTVHVL------------------PTFTELPGDVSLNKGEQLRLSC 1319
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
K P P L W ++ + G E L I+ + D + C A N G
Sbjct: 1320 KATGIPLPKLTWTFNNNIIPAHFDSVNGHSE-----LVIERVSKEDSGTYVCTAENSVGF 1374
Query: 277 SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPG 336
F+ + P +K ++ + G L C+V G P P ++W + G +++
Sbjct: 1375 VKAIGFVYVKEPPVFKGDYPSHWIEPL---GGNAILNCEVKGDPTPTIQWNRKGVDIEIS 1431
Query: 337 DIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
HRI +G+ ++ G YTC A+N GV S SL
Sbjct: 1432 --HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 1472
Score = 44.4 bits (100), Expect = 0.007
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W R ++ S R + G L I D ++ CVA N+ G S
Sbjct: 1415 PTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSM 1470
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L L P LE ++ +++ G + L C+ G PQP + W + G + D +
Sbjct: 1471 SLTLQSPPIIT----LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNV 1526
Query: 342 IS 343
+S
Sbjct: 1527 LS 1528
Score = 42.3 bits (95), Expect = 0.027
Identities = 61/275 (22%), Positives = 100/275 (36%), Gaps = 45/275 (16%)
Query: 117 ECKVVGFPTPVLSWFKDGQEL----------KPGDVY-QLTGTNSLGSYCCIAKNCMGQA 165
EC G PTP ++W KDG L + G ++ Q G Y C+A N G
Sbjct: 771 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 830
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+L V + P G ++ ++ + P+PS
Sbjct: 831 RRRIDLQV------------------HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPS 872
Query: 226 LLWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
+ W ++ VD++ + + + +++ D A ++C N G + L
Sbjct: 873 INWRKNGHLLNVDQNQNSYRLLSSGSLVIIS-PSVD--DTATYECTVTNGAGDDKRTVDL 929
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRII 342
+ +P E +++ + C GVP P + W K+G L P GD +RI+
Sbjct: 930 TVQVPPSIAD----EPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRIL 985
Query: 343 SG------QDGTCSLGTYTCEASNCMGVAASSASL 371
S G YTC A N G A +L
Sbjct: 986 SSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTL 1020
Score = 35.9 bits (79), Expect = 2.3
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G C+V G PTP + W + G +++ + G SL Y + ++ G + A
Sbjct: 1403 GNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATN 1461
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI--KVAIPPEPSLLWY 229
++ ++ L L Q+P + L+ VE I+ + + + P+P++ W
Sbjct: 1462 EAGVVERSMS----LTL----QSPPII-TLEPVETVINAGGKIILNCQATGEPQPTITWS 1512
Query: 230 RDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
R + R ++ ++ D Q D +E++CVA N G
Sbjct: 1513 RQGHSISWDDRVNV-LSNNSLYIADAQK---EDTSEFECVARNLMG 1554
Score = 35.9 bits (79), Expect = 2.3
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL--------- 151
+E ++ V+ G + C+ G P P ++W + G + D + NSL
Sbjct: 1482 LEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKED 1541
Query: 152 -GSYCCIAKNCMG 163
+ C+A+N MG
Sbjct: 1542 TSEFECVARNLMG 1554
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell
adhesion molecule splice variant protein.
Length = 1746
Score = 75.4 bits (177), Expect = 3e-12
Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 15/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C V G LSW+++G+ L PG ++TG N I + + + + V
Sbjct: 83 VSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN---LIMDHMVKSDGGAYQCFV 139
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+++L+ ++ +Q+ ++ PK + EP V P P++ W DD
Sbjct: 140 R--KDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD 197
Query: 234 PVDESSRCHLGK----EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ + + + E V +L+I + + D ++C A N G + + + P
Sbjct: 198 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 257
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R ++N+ AI + + C+VIG P +KWYK+ L P + ++ +GT
Sbjct: 258 SI---RPMKNITAIAGRD--TYIHCRVIGYPYYSIKWYKN-SNLLPFNHRQVAFENNGTL 311
Query: 350 SL 351
L
Sbjct: 312 KL 313
Score = 48.0 bits (109), Expect = 5e-04
Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 13/122 (10%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
PEP W +D+ P++ S G+ ++ V L I+ + D + C N +G +
Sbjct: 4 PEPDYRWLKDNMPLELS-----GRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTA---- 54
Query: 282 FLKLIIPRHYKKP-RFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIH 339
K+I + K+P + + + + S G+ V+L C V G L WY++GE L PG
Sbjct: 55 --KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNV 112
Query: 340 RI 341
RI
Sbjct: 113 RI 114
Score = 37.9 bits (84), Expect = 0.57
Identities = 49/233 (21%), Positives = 92/233 (39%), Gaps = 22/233 (9%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
R M+N+ A+ + + C+V+G+P + W+K+ L P + Q+ N+
Sbjct: 260 RPMKNITAIAGRDTYI--HCRVIGYPYYSIKWYKNSN-LLPFNHRQVAFENNGTLKLSDV 316
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ + + + + V Q QL+ + + + K P F+ + I + V
Sbjct: 317 QKEVDEGEYTCNVLV---QPQLSTSQSVHVTVK--VPPFIQPFEFPRFSIGQRVFIPCVV 371
Query: 219 AIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFF---LDIQALEFLDQAEWKCVAFNDF 274
P ++ W +D +P+ S LG + F L I L + + C+A N+
Sbjct: 372 VSGDLPITITWQKDGRPIPGS----LGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEA 427
Query: 275 GQ-SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
S + + P+ +PR + + AV L C G P P + W
Sbjct: 428 AAVEHQSQLIVRVPPKFVVQPRDQDGIYG-----KAVILNCSAEGYPVPTIVW 475
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 2012
Score = 75.4 bits (177), Expect = 3e-12
Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 15/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C V G LSW+++G+ L PG ++TG N I + + + + V
Sbjct: 331 VSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN---LIMDHMVKSDGGAYQCFV 387
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+++L+ ++ +Q+ ++ PK + EP V P P++ W DD
Sbjct: 388 R--KDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD 445
Query: 234 PVDESSRCHLGK----EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ + + + E V +L+I + + D ++C A N G + + + P
Sbjct: 446 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 505
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R ++N+ AI + + C+VIG P +KWYK+ L P + ++ +GT
Sbjct: 506 SI---RPMKNITAIAGRD--TYIHCRVIGYPYYSIKWYKN-SNLLPFNHRQVAFENNGTL 559
Query: 350 SL 351
L
Sbjct: 560 KL 561
Score = 61.3 bits (142), Expect = 5e-08
Identities = 58/220 (26%), Positives = 94/220 (42%), Gaps = 19/220 (8%)
Query: 127 VLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKL 186
V+SW KD L G + +T T +L Y +N G + +T + +
Sbjct: 157 VVSWEKDTVSLVSGSRFLITSTGAL--YIKDVQNEDGLYNYRC-ITRHRYTGETRQSNSA 213
Query: 187 QLFSK---NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
+LF N AP + G +A + K PEP W +D+ P++ S
Sbjct: 214 RLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELS----- 268
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP-RFLENLQA 302
G+ ++ V L I+ + D + C N +G + K+I + K+P + + +
Sbjct: 269 GRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTA------KVIGRLYVKQPLKATISPRK 322
Query: 303 ILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+ S G+ V+L C V G L WY++GE L PG RI
Sbjct: 323 VKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 362
Score = 47.6 bits (108), Expect = 7e-04
Identities = 56/273 (20%), Positives = 99/273 (36%), Gaps = 30/273 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V CK +G P P W KD L+ +Q T T L +N S S V
Sbjct: 242 VELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLL------IENIRPSDSGS---YV 292
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
++ N+ + + Q K + V++ + + V + L WYR+ +
Sbjct: 293 CEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGE 352
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
++ + +D D ++C D + ++++++
Sbjct: 353 ILNPGKNVRITGINHENLIMDHMVKS--DGGAYQCFVRKD--KLSAQDYVQVVL--EDGT 406
Query: 294 PRFLENL-QAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI---ISGQDGTC 349
P+ + + ++S V+L C V G P P + W D + + G HRI I+ +
Sbjct: 407 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 466
Query: 350 SL-----------GTYTCEASNCMGVAASSASL 371
S G Y C A+N GV A +
Sbjct: 467 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 499
Score = 37.9 bits (84), Expect = 0.57
Identities = 49/233 (21%), Positives = 92/233 (39%), Gaps = 22/233 (9%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
R M+N+ A+ + + C+V+G+P + W+K+ L P + Q+ N+
Sbjct: 508 RPMKNITAIAGRDTYI--HCRVIGYPYYSIKWYKNSN-LLPFNHRQVAFENNGTLKLSDV 564
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ + + + + V Q QL+ + + + K P F+ + I + V
Sbjct: 565 QKEVDEGEYTCNVLV---QPQLSTSQSVHVTVK--VPPFIQPFEFPRFSIGQRVFIPCVV 619
Query: 219 AIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFF---LDIQALEFLDQAEWKCVAFNDF 274
P ++ W +D +P+ S LG + F L I L + + C+A N+
Sbjct: 620 VSGDLPITITWQKDGRPIPGS----LGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEA 675
Query: 275 GQ-SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
S + + P+ +PR + + AV L C G P P + W
Sbjct: 676 AAVEHQSQLIVRVPPKFVVQPRDQDGIYG-----KAVILNCSAEGYPVPTIVW 723
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1571
Score = 75.4 bits (177), Expect = 3e-12
Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 15/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C V G LSW+++G+ L PG ++TG N I + + + + V
Sbjct: 331 VSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN---LIMDHMVKSDGGAYQCFV 387
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+++L+ ++ +Q+ ++ PK + EP V P P++ W DD
Sbjct: 388 R--KDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD 445
Query: 234 PVDESSRCHLGK----EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ + + + E V +L+I + + D ++C A N G + + + P
Sbjct: 446 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 505
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R ++N+ AI + + C+VIG P +KWYK+ L P + ++ +GT
Sbjct: 506 SI---RPMKNITAIAGRD--TYIHCRVIGYPYYSIKWYKN-SNLLPFNHRQVAFENNGTL 559
Query: 350 SL 351
L
Sbjct: 560 KL 561
Score = 61.3 bits (142), Expect = 5e-08
Identities = 58/220 (26%), Positives = 94/220 (42%), Gaps = 19/220 (8%)
Query: 127 VLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKL 186
V+SW KD L G + +T T +L Y +N G + +T + +
Sbjct: 157 VVSWEKDTVSLVSGSRFLITSTGAL--YIKDVQNEDGLYNYRC-ITRHRYTGETRQSNSA 213
Query: 187 QLFSK---NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
+LF N AP + G +A + K PEP W +D+ P++ S
Sbjct: 214 RLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELS----- 268
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP-RFLENLQA 302
G+ ++ V L I+ + D + C N +G + K+I + K+P + + +
Sbjct: 269 GRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTA------KVIGRLYVKQPLKATISPRK 322
Query: 303 ILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+ S G+ V+L C V G L WY++GE L PG RI
Sbjct: 323 VKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 362
Score = 47.6 bits (108), Expect = 7e-04
Identities = 56/273 (20%), Positives = 99/273 (36%), Gaps = 30/273 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V CK +G P P W KD L+ +Q T T L +N S S V
Sbjct: 242 VELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLL------IENIRPSDSGS---YV 292
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
++ N+ + + Q K + V++ + + V + L WYR+ +
Sbjct: 293 CEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGE 352
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
++ + +D D ++C D + ++++++
Sbjct: 353 ILNPGKNVRITGINHENLIMDHMVKS--DGGAYQCFVRKD--KLSAQDYVQVVL--EDGT 406
Query: 294 PRFLENL-QAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI---ISGQDGTC 349
P+ + + ++S V+L C V G P P + W D + + G HRI I+ +
Sbjct: 407 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 466
Query: 350 SL-----------GTYTCEASNCMGVAASSASL 371
S G Y C A+N GV A +
Sbjct: 467 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 499
Score = 37.9 bits (84), Expect = 0.57
Identities = 49/233 (21%), Positives = 92/233 (39%), Gaps = 22/233 (9%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
R M+N+ A+ + + C+V+G+P + W+K+ L P + Q+ N+
Sbjct: 508 RPMKNITAIAGRDTYI--HCRVIGYPYYSIKWYKNSN-LLPFNHRQVAFENNGTLKLSDV 564
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ + + + + V Q QL+ + + + K P F+ + I + V
Sbjct: 565 QKEVDEGEYTCNVLV---QPQLSTSQSVHVTVK--VPPFIQPFEFPRFSIGQRVFIPCVV 619
Query: 219 AIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFF---LDIQALEFLDQAEWKCVAFNDF 274
P ++ W +D +P+ S LG + F L I L + + C+A N+
Sbjct: 620 VSGDLPITITWQKDGRPIPGS----LGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEA 675
Query: 275 GQ-SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
S + + P+ +PR + + AV L C G P P + W
Sbjct: 676 AAVEHQSQLIVRVPPKFVVQPRDQDGIYG-----KAVILNCSAEGYPVPTIVW 723
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1896
Score = 75.4 bits (177), Expect = 3e-12
Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 15/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C V G LSW+++G+ L PG ++TG N I + + + + V
Sbjct: 317 VSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN---LIMDHMVKSDGGAYQCFV 373
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+++L+ ++ +Q+ ++ PK + EP V P P++ W DD
Sbjct: 374 R--KDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD 431
Query: 234 PVDESSRCHLGK----EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ + + + E V +L+I + + D ++C A N G + + + P
Sbjct: 432 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 491
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R ++N+ AI + + C+VIG P +KWYK+ L P + ++ +GT
Sbjct: 492 SI---RPMKNITAIAGRD--TYIHCRVIGYPYYSIKWYKN-SNLLPFNHRQVAFENNGTL 545
Query: 350 SL 351
L
Sbjct: 546 KL 547
Score = 61.3 bits (142), Expect = 5e-08
Identities = 58/220 (26%), Positives = 94/220 (42%), Gaps = 19/220 (8%)
Query: 127 VLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKL 186
V+SW KD L G + +T T +L Y +N G + +T + +
Sbjct: 143 VVSWEKDTVSLVSGSRFLITSTGAL--YIKDVQNEDGLYNYRC-ITRHRYTGETRQSNSA 199
Query: 187 QLFSK---NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
+LF N AP + G +A + K PEP W +D+ P++ S
Sbjct: 200 RLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELS----- 254
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP-RFLENLQA 302
G+ ++ V L I+ + D + C N +G + K+I + K+P + + +
Sbjct: 255 GRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTA------KVIGRLYVKQPLKATISPRK 308
Query: 303 ILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+ S G+ V+L C V G L WY++GE L PG RI
Sbjct: 309 VKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 348
Score = 47.6 bits (108), Expect = 7e-04
Identities = 56/273 (20%), Positives = 99/273 (36%), Gaps = 30/273 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V CK +G P P W KD L+ +Q T T L +N S S V
Sbjct: 228 VELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLL------IENIRPSDSGS---YV 278
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
++ N+ + + Q K + V++ + + V + L WYR+ +
Sbjct: 279 CEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGE 338
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
++ + +D D ++C D + ++++++
Sbjct: 339 ILNPGKNVRITGINHENLIMDHMVKS--DGGAYQCFVRKD--KLSAQDYVQVVL--EDGT 392
Query: 294 PRFLENL-QAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI---ISGQDGTC 349
P+ + + ++S V+L C V G P P + W D + + G HRI I+ +
Sbjct: 393 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 452
Query: 350 SL-----------GTYTCEASNCMGVAASSASL 371
S G Y C A+N GV A +
Sbjct: 453 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 485
Score = 37.9 bits (84), Expect = 0.57
Identities = 49/233 (21%), Positives = 92/233 (39%), Gaps = 22/233 (9%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
R M+N+ A+ + + C+V+G+P + W+K+ L P + Q+ N+
Sbjct: 494 RPMKNITAIAGRDTYI--HCRVIGYPYYSIKWYKNSN-LLPFNHRQVAFENNGTLKLSDV 550
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ + + + + V Q QL+ + + + K P F+ + I + V
Sbjct: 551 QKEVDEGEYTCNVLV---QPQLSTSQSVHVTVK--VPPFIQPFEFPRFSIGQRVFIPCVV 605
Query: 219 AIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFF---LDIQALEFLDQAEWKCVAFNDF 274
P ++ W +D +P+ S LG + F L I L + + C+A N+
Sbjct: 606 VSGDLPITITWQKDGRPIPGS----LGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEA 661
Query: 275 GQ-SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
S + + P+ +PR + + AV L C G P P + W
Sbjct: 662 AAVEHQSQLIVRVPPKFVVQPRDQDGIYG-----KAVILNCSAEGYPVPTIVW 709
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell
adhesion molecule isoform CHD2-42 precursor variant
protein.
Length = 2023
Score = 75.4 bits (177), Expect = 3e-12
Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 15/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
VS C V G LSW+++G+ L PG ++TG N I + + + + V
Sbjct: 342 VSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN---LIMDHMVKSDGGAYQCFV 398
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+++L+ ++ +Q+ ++ PK + EP V P P++ W DD
Sbjct: 399 R--KDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD 456
Query: 234 PVDESSRCHLGK----EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ + + + E V +L+I + + D ++C A N G + + + P
Sbjct: 457 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 516
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R ++N+ AI + + C+VIG P +KWYK+ L P + ++ +GT
Sbjct: 517 SI---RPMKNITAIAGRD--TYIHCRVIGYPYYSIKWYKN-SNLLPFNHRQVAFENNGTL 570
Query: 350 SL 351
L
Sbjct: 571 KL 572
Score = 62.1 bits (144), Expect = 3e-08
Identities = 58/220 (26%), Positives = 95/220 (43%), Gaps = 19/220 (8%)
Query: 127 VLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKL 186
V+SW KD L G + +T T +L Y +N G + +T + +
Sbjct: 168 VVSWEKDTVSLVSGSRFLITSTGAL--YIKDVQNEDGLYNYRC-ITRHRYTGETRQSNSA 224
Query: 187 QLFSK---NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
+LF N AP + G + +A + K PEP W +D+ P++ S
Sbjct: 225 RLFVSDPANSAPSILDGFEHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELS----- 279
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKP-RFLENLQA 302
G+ ++ V L I+ + D + C N +G + K+I + K+P + + +
Sbjct: 280 GRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTA------KVIGRLYVKQPLKATISPRK 333
Query: 303 ILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
+ S G+ V+L C V G L WY++GE L PG RI
Sbjct: 334 VKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRI 373
Score = 47.6 bits (108), Expect = 7e-04
Identities = 56/273 (20%), Positives = 99/273 (36%), Gaps = 30/273 (10%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V CK +G P P W KD L+ +Q T T L +N S S V
Sbjct: 253 VELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLL------IENIRPSDSGS---YV 303
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
++ N+ + + Q K + V++ + + V + L WYR+ +
Sbjct: 304 CEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGE 363
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
++ + +D D ++C D + ++++++
Sbjct: 364 ILNPGKNVRITGINHENLIMDHMVKS--DGGAYQCFVRKD--KLSAQDYVQVVL--EDGT 417
Query: 294 PRFLENL-QAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI---ISGQDGTC 349
P+ + + ++S V+L C V G P P + W D + + G HRI I+ +
Sbjct: 418 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 477
Query: 350 SL-----------GTYTCEASNCMGVAASSASL 371
S G Y C A+N GV A +
Sbjct: 478 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARI 510
Score = 37.9 bits (84), Expect = 0.57
Identities = 49/233 (21%), Positives = 92/233 (39%), Gaps = 22/233 (9%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
R M+N+ A+ + + C+V+G+P + W+K+ L P + Q+ N+
Sbjct: 519 RPMKNITAIAGRDTYI--HCRVIGYPYYSIKWYKNSN-LLPFNHRQVAFENNGTLKLSDV 575
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+ + + + + V Q QL+ + + + K P F+ + I + V
Sbjct: 576 QKEVDEGEYTCNVLV---QPQLSTSQSVHVTVK--VPPFIQPFEFPRFSIGQRVFIPCVV 630
Query: 219 AIPPEP-SLLWYRDDQPVDESSRCHLGKEERGVFF---LDIQALEFLDQAEWKCVAFNDF 274
P ++ W +D +P+ S LG + F L I L + + C+A N+
Sbjct: 631 VSGDLPITITWQKDGRPIPGS----LGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEA 686
Query: 275 GQ-SVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKW 326
S + + P+ +PR + + AV L C G P P + W
Sbjct: 687 AAVEHQSQLIVRVPPKFVVQPRDQDGIYG-----KAVILNCSAEGYPVPTIVW 734
>X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for a
nontransmembrane isoform of N-CAM from skeletal muscle.
).
Length = 761
Score = 74.5 bits (175), Expect = 5e-12
Identities = 71/294 (24%), Positives = 129/294 (43%), Gaps = 27/294 (9%)
Query: 78 FKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL 137
FK I++I N PT+ + N A L + V+ C GFP P +SW KDG+++
Sbjct: 201 FKDIQVIVNVPPTIQARQN----IVNATANLGQS--VTLVCDAEGFPEPTMSWTKDGEQI 254
Query: 138 KPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK---LQLFSKNQA 194
+ + + + S I K + AE + +N+ E++ L++F+K
Sbjct: 255 EQEEDDEKYIFSDDSSQLTIKKV---DKNDEAEY-ICIAENKAGEQDATIHLKVFAK--- 307
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLG----KEERGV 250
PK + +++E T + + P PS+ W + + + G + V
Sbjct: 308 PKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARV 367
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-A 309
L ++++++ D E+ C A N GQ S +L++ Y P+ L+ A+ + EG
Sbjct: 368 SSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV----QYA-PK-LQGPVAVYTWEGNQ 421
Query: 310 VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCEASNCMG 363
VN+ C+V P + W++DG+ L + I + S T ++ N G
Sbjct: 422 VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFG 475
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 74.5 bits (175), Expect = 5e-12
Identities = 71/294 (24%), Positives = 129/294 (43%), Gaps = 27/294 (9%)
Query: 78 FKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL 137
FK I++I N PT+ + N A L + V+ C GFP P +SW KDG+++
Sbjct: 201 FKDIQVIVNVPPTIQARQN----IVNATANLGQS--VTLVCDAEGFPEPTMSWTKDGEQI 254
Query: 138 KPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK---LQLFSKNQA 194
+ + + + S I K + AE + +N+ E++ L++F+K
Sbjct: 255 EQEEDDEKYIFSDDSSQLTIKKV---DKNDEAEY-ICIAENKAGEQDATIHLKVFAK--- 307
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLG----KEERGV 250
PK + +++E T + + P PS+ W + + + G + V
Sbjct: 308 PKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARV 367
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-A 309
L ++++++ D E+ C A N GQ S +L++ Y P+ L+ A+ + EG
Sbjct: 368 SSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV----QYA-PK-LQGPVAVYTWEGNQ 421
Query: 310 VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCEASNCMG 363
VN+ C+V P + W++DG+ L + I + S T ++ N G
Sbjct: 422 VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFG 475
>L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphatase
delta protein.
Length = 1912
Score = 74.5 bits (175), Expect = 5e-12
Identities = 65/279 (23%), Positives = 117/279 (41%), Gaps = 19/279 (6%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQAEWKCVAFNDFG---Q 276
W++D PVD S+ K+ R L I+ E DQ +++CVA N G
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYS 218
Query: 277 SVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + +++ + PRF + + G+VN+ C +G P P +KW E+L P
Sbjct: 219 APANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 278
Query: 336 GD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
D I R + + YTC A + +GV + A +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 317
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 251 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 311 IEAIAQITVK 320
>BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 74.5 bits (175), Expect = 5e-12
Identities = 65/279 (23%), Positives = 117/279 (41%), Gaps = 19/279 (6%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQAEWKCVAFNDFG---Q 276
W++D PVD S+ K+ R L I+ E DQ +++CVA N G
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYS 218
Query: 277 SVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + +++ + PRF + + G+VN+ C +G P P +KW E+L P
Sbjct: 219 APANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 278
Query: 336 GD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
D I R + + YTC A + +GV + A +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 317
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 251 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 311 IEAIAQITVK 320
>BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.
Length = 1506
Score = 74.5 bits (175), Expect = 5e-12
Identities = 65/279 (23%), Positives = 117/279 (41%), Gaps = 19/279 (6%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQAEWKCVAFNDFG---Q 276
W++D PVD S+ K+ R L I+ E DQ +++CVA N G
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYS 218
Query: 277 SVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + +++ + PRF + + G+VN+ C +G P P +KW E+L P
Sbjct: 219 APANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 278
Query: 336 GD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
D I R + + YTC A + +GV + A +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 317
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 251 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 311 IEAIAQITVK 320
>AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 74.5 bits (175), Expect = 5e-12
Identities = 65/279 (23%), Positives = 117/279 (41%), Gaps = 19/279 (6%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQAEWKCVAFNDFG---Q 276
W++D PVD S+ K+ R L I+ E DQ +++CVA N G
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYS 218
Query: 277 SVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + +++ + PRF + + G+VN+ C +G P P +KW E+L P
Sbjct: 219 APANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 278
Query: 336 GD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
D I R + + YTC A + +GV + A +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 317
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 251 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 311 IEAIAQITVK 320
>AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 74.5 bits (175), Expect = 5e-12
Identities = 65/279 (23%), Positives = 117/279 (41%), Gaps = 19/279 (6%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQAEWKCVAFNDFG---Q 276
W++D PVD S+ K+ R L I+ E DQ +++CVA N G
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYS 218
Query: 277 SVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + +++ + PRF + + G+VN+ C +G P P +KW E+L P
Sbjct: 219 APANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 278
Query: 336 GD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
D I R + + YTC A + +GV + A +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 317
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 251 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 311 IEAIAQITVK 320
>AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 74.5 bits (175), Expect = 5e-12
Identities = 65/279 (23%), Positives = 117/279 (41%), Gaps = 19/279 (6%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQAEWKCVAFNDFG---Q 276
W++D PVD S+ K+ R L I+ E DQ +++CVA N G
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYS 218
Query: 277 SVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + +++ + PRF + + G+VN+ C +G P P +KW E+L P
Sbjct: 219 APANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 278
Query: 336 GD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
D I R + + YTC A + +GV + A +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 317
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 251 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 311 IEAIAQITVK 320
>AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 74.5 bits (175), Expect = 5e-12
Identities = 65/279 (23%), Positives = 117/279 (41%), Gaps = 19/279 (6%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQAEWKCVAFNDFG---Q 276
W++D PVD S+ K+ R L I+ E DQ +++CVA N G
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYS 218
Query: 277 SVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + +++ + PRF + + G+VN+ C +G P P +KW E+L P
Sbjct: 219 APANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 278
Query: 336 GD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
D I R + + YTC A + +GV + A +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 317
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 251 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 311 IEAIAQITVK 320
>AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 74.5 bits (175), Expect = 5e-12
Identities = 65/279 (23%), Positives = 117/279 (41%), Gaps = 19/279 (6%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQAEWKCVAFNDFG---Q 276
W++D PVD S+ K+ R L I+ E DQ +++CVA N G
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYS 218
Query: 277 SVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + +++ + PRF + + G+VN+ C +G P P +KW E+L P
Sbjct: 219 APANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 278
Query: 336 GD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
D I R + + YTC A + +GV + A +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 317
Score = 39.9 bits (89), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 251 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310
Query: 165 ASSSAELTVE 174
+ A++TV+
Sbjct: 311 IEAIAQITVK 320
>AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine
phosphatase receptor type D protein.
Length = 1912
Score = 74.5 bits (175), Expect = 5e-12
Identities = 65/279 (23%), Positives = 117/279 (41%), Gaps = 19/279 (6%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P + W K G+++ + + GS I + + E
Sbjct: 39 GVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYEC 98
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK-SVEAKIDEPFRFTIKVAIP---PEPSLL 227
+ +++ +L + ++Q P+ + + K+ E R + P+P +
Sbjct: 99 VASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIT 158
Query: 228 WYRDDQPVDESSRCHLGKEERGVFF--------LDIQALEFLDQAEWKCVAFNDFG---Q 276
W++D PVD S+ K+ R L I+ E DQ +++CVA N G
Sbjct: 159 WFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYS 218
Query: 277 SVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + +++ + PRF + + G+VN+ C +G P P +KW E+L P
Sbjct: 219 APANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 278
Query: 336 GD---IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
D I R + + YTC A + +GV + A +
Sbjct: 279 EDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQI 317
Score = 40.3 bits (90), Expect = 0.11
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 7/72 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W ++L P D V +L +Y C+A + +G
Sbjct: 251 GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310
Query: 165 ASSSAELTVEDI 176
+ A++TV+ +
Sbjct: 311 IEAIAQITVKPL 322
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 74.5 bits (175), Expect = 5e-12
Identities = 71/294 (24%), Positives = 129/294 (43%), Gaps = 27/294 (9%)
Query: 78 FKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL 137
FK I++I N PT+ + N A L + V+ C GFP P +SW KDG+++
Sbjct: 282 FKDIQVIVNVPPTIQARQN----IVNATANLGQS--VTLVCDAEGFPEPTMSWTKDGEQI 335
Query: 138 KPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK---LQLFSKNQA 194
+ + + + S I K + AE + +N+ E++ L++F+K
Sbjct: 336 EQEEDDEKYIFSDDSSQLTIKKV---DKNDEAEY-ICIAENKAGEQDATIHLKVFAK--- 388
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLG----KEERGV 250
PK + +++E T + + P PS+ W + + + G + V
Sbjct: 389 PKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARV 448
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-A 309
L ++++++ D E+ C A N GQ S +L++ Y P+ L+ A+ + EG
Sbjct: 449 SSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV----QYA-PK-LQGPVAVYTWEGNQ 502
Query: 310 VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCEASNCMG 363
VN+ C+V P + W++DG+ L + I + S T ++ N G
Sbjct: 503 VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFG 556
>AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein.
Length = 1264
Score = 73.3 bits (172), Expect = 1e-11
Identities = 64/223 (28%), Positives = 97/223 (43%), Gaps = 31/223 (13%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD----VYQLTGTNSL-----GSYCCIAKNCMGQ 164
V+ EC V G P P + W KDGQ++ PG +Y T+S+ G+Y C+A N G
Sbjct: 239 VTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGD 298
Query: 165 ASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEP 224
VE + +N E + SK GL+ + FT V P P
Sbjct: 299 --------VEYVTYMVNVLEHASI-SK--------GLQDQIVSLGATVHFTCDVHGNPAP 341
Query: 225 SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
+ W+ + QP+ S+R HL L I + D ++CVA N G ++ L+
Sbjct: 342 NCTWFHNAQPIHPSAR-HLTAGNG----LKISGVTVEDVGMYQCVADNGIGFMHSTGRLE 396
Query: 285 LIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
+ +K + A ++D V L C G+P PV++WY
Sbjct: 397 IENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWY 439
Score = 52.8 bits (121), Expect = 2e-05
Identities = 76/285 (26%), Positives = 116/285 (40%), Gaps = 44/285 (15%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG----DVYQLTGT----NS--L 151
E L AV G V C T + SW +G+ L ++Q T T NS L
Sbjct: 34 EPLSAVQKLGGPVVLHCSAQPVTTRI-SWLHNGKTLDGNLEHIKIHQGTLTILSLNSSLL 92
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C+A N +G S + K + ++ ++ F+ G + E+
Sbjct: 93 GYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFI-GCRVPESNPKAE 151
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
R+ I+ W ++ S+ +L + L++ +LE D+ +KC A+
Sbjct: 152 VRYKIRGK--------W------LEHSTENYLILPSGNLQILNV-SLE--DKGSYKCAAY 194
Query: 272 NDFGQS--VTSCFLKLIIPR------HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPV 323
N V KL++ R H P + L A+LS V LEC V GVP P
Sbjct: 195 NPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQAL-AVLS-RSPVTLECVVSGVPAPQ 252
Query: 324 LKWYKDGEELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMG 363
+ W KDG+++ PG R + T S+ G Y+C A N G
Sbjct: 253 VYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSG 297
Score = 37.9 bits (84), Expect = 0.57
Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 15/156 (9%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P + W +D Q + S R L +++ D + C+A N G
Sbjct: 249 PAPQVYWLKDGQDIAPGSNWR-----RLYSHLATDSVDPADSGNYSCMAGNKSGDVEYVT 303
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ ++ H + L++ I+S V+ C V G P P W+ + + + P H +
Sbjct: 304 YMVNVL-EHASISKGLQD--QIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARH-L 359
Query: 342 ISGQDGTCS------LGTYTCEASNCMGVAASSASL 371
+G S +G Y C A N +G S+ L
Sbjct: 360 TAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRL 395
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion
molecule CD56 protein.
Length = 848
Score = 72.5 bits (170), Expect = 2e-11
Identities = 71/294 (24%), Positives = 130/294 (44%), Gaps = 27/294 (9%)
Query: 78 FKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL 137
FK I++I N PT+ R + + N A L + V+ C FP P +SW KDG+++
Sbjct: 201 FKDIQVIVNVPPTI----RARQNIVNATANLGQS--VTLVCDAERFPEPTMSWTKDGEQI 254
Query: 138 KPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK---LQLFSKNQA 194
+ + + + S I K + AE + +N+ E++ L++F+K
Sbjct: 255 EQEEDDEKYIFSDDSSQLTIKKV---DKNDEAEY-ICIAENKAGEQDATIHLKVFAK--- 307
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLG----KEERGV 250
PK + +++E T + + P PS+ W + + + G + V
Sbjct: 308 PKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARV 367
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-A 309
L ++++++ D E+ C A N GQ S +L++ Y P+ L+ A+ + EG
Sbjct: 368 SSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV----QYA-PK-LQGPVAVYTWEGNQ 421
Query: 310 VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCEASNCMG 363
VN+ C+V P + W++DG+ L + I + S T ++ N G
Sbjct: 422 VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFG 475
>BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1264
Score = 71.7 bits (168), Expect = 4e-11
Identities = 63/223 (28%), Positives = 97/223 (43%), Gaps = 31/223 (13%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD----VYQLTGTNSL-----GSYCCIAKNCMGQ 164
V+ EC V G P P + W KDGQ++ PG +Y T+S+ G+Y C+A N G
Sbjct: 239 VTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSGD 298
Query: 165 ASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEP 224
V+ + +N E + SK GL+ + FT V P P
Sbjct: 299 --------VKYVTYMVNVLEHASI-SK--------GLQDQIVSLGATVHFTCDVHGNPAP 341
Query: 225 SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
+ W+ + QP+ S+R HL L I + D ++CVA N G ++ L+
Sbjct: 342 NCTWFHNAQPIHPSAR-HLTAGNG----LKISGVTVEDVGMYQCVADNGIGFMHSTGRLE 396
Query: 285 LIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
+ +K + A ++D V L C G+P PV++WY
Sbjct: 397 IENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWY 439
Score = 52.0 bits (119), Expect = 3e-05
Identities = 76/285 (26%), Positives = 115/285 (40%), Gaps = 44/285 (15%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG----DVYQLTGT----NS--L 151
E L AV G V C T + SW +G+ L ++Q T T NS L
Sbjct: 34 EPLSAVQKLGGPVVLHCSAQPVTTRI-SWLHNGKTLDGNLEHIKIHQGTLTILSLNSSLL 92
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C+A N +G S + K + ++ ++ F+ G + E+
Sbjct: 93 GYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFI-GCRVPESNPKAE 151
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
R+ I+ W + S+ +L + L++ +LE D+ +KC A+
Sbjct: 152 VRYKIRGK--------WLK------HSTENYLILPSGNLQILNV-SLE--DKGSYKCAAY 194
Query: 272 NDFGQS--VTSCFLKLIIPR------HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPV 323
N V KL++ R H P + L A+LS V LEC V GVP P
Sbjct: 195 NPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQAL-AVLS-RSPVTLECVVSGVPAPQ 252
Query: 324 LKWYKDGEELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMG 363
+ W KDG+++ PG R + T S+ G Y+C A N G
Sbjct: 253 VYWLKDGQDIAPGSNWRRLYSHLATDSVDPADSGNYSCMAGNKSG 297
Score = 37.9 bits (84), Expect = 0.57
Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 15/156 (9%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P + W +D Q + S R L +++ D + C+A N G
Sbjct: 249 PAPQVYWLKDGQDIAPGSNWR-----RLYSHLATDSVDPADSGNYSCMAGNKSGDVKYVT 303
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ ++ H + L++ I+S V+ C V G P P W+ + + + P H +
Sbjct: 304 YMVNVL-EHASISKGLQD--QIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARH-L 359
Query: 342 ISGQDGTCS------LGTYTCEASNCMGVAASSASL 371
+G S +G Y C A N +G S+ L
Sbjct: 360 TAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRL 395
>AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform
protein.
Length = 2154
Score = 70.5 bits (165), Expect = 9e-11
Identities = 54/198 (27%), Positives = 91/198 (45%), Gaps = 22/198 (11%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+ + L+ V + +P RF ++ P+P + WY+++Q + +C + +
Sbjct: 793 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 852
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK--------KPRFLENLQAIL 304
L I+A D A + C A ND+G + TS L + +P P + LQ +
Sbjct: 853 LLIEAFP-EDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 911
Query: 305 SDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GT 353
+ EG +C+V G V WY +++KP R+ +D T L GT
Sbjct: 912 TSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGT 969
Query: 354 YTCEASNCMGVAASSASL 371
YT ASN +G +S+A+L
Sbjct: 970 YTFVASNAVGQVSSTANL 987
Score = 62.9 bits (146), Expect = 2e-08
Identities = 65/264 (24%), Positives = 113/264 (42%), Gaps = 28/264 (10%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P + LQ +T EG + F+C+V G V SW+ +++KP D YQL
Sbjct: 901 PAIITPLQDTVTSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFEDTYQLEI 959
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVEDI----QNQLNEEEKLQL---FSKN---Q 193
+ G+Y +A N +GQ SS+A L++E +N N + + L F K Q
Sbjct: 960 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQ 1019
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFL 253
P F+ L S+ E RF +V+ P+P + W+ + Q + + EE L
Sbjct: 1020 KPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMAL 1079
Query: 254 DIQALEFLDQA-EWKCVAFNDFGQSVTSCFLKLI--IPRHYKKPRFLENLQAILSDEGAV 310
+ + + A ++ C A N G++ + L + P R + ++ + + +
Sbjct: 1080 MLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSS 1139
Query: 311 NLECKVIGVPQPVLKWYKDGEELK 334
L + G+ L+ K E L+
Sbjct: 1140 FLSAEEEGLHSAELQLSKINETLE 1163
Score = 58.0 bits (134), Expect = 5e-07
Identities = 75/323 (23%), Positives = 136/323 (42%), Gaps = 56/323 (17%)
Query: 98 PRFMENLQAVLTEEGLVSFECKVV-GFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ ++ LQ V + G + C V+ G P P +SW+K+ Q L G Y L
Sbjct: 795 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 854
Query: 148 TNSLGS----YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+ Y C AKN G A++SA L+VE + ++ ++++ ++ P + L+
Sbjct: 855 IEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVY----PPAIITPLQD 909
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+P RF +V+ + + WY D+ + + SR + + L+I D+
Sbjct: 910 TVTSEGQPARFQCRVS-GTDLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDE 967
Query: 264 AEWKCVAFNDFGQSVTSCFLKL-----------------IIPRHYK------KPRFLENL 300
+ VA N GQ ++ L L + +K KP F++ L
Sbjct: 968 GTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPL 1027
Query: 301 QAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKP-GDIHRIISGQDGTCSL------- 351
++ G V +V G+P+P ++W+ + + + P D+ G +
Sbjct: 1028 SSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYS 1087
Query: 352 ---GTYTCEASNCMGVAASSASL 371
G Y+C+A+N G A +A+L
Sbjct: 1088 EHAGQYSCKAANSAGEATCAATL 1110
Score = 52.0 bits (119), Expect = 3e-05
Identities = 47/211 (22%), Positives = 95/211 (45%), Gaps = 36/211 (17%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS--RCHLGKEERGVFF 252
P F+ + + + + + ++ V P+P + W+ + + S+ + ++ +
Sbjct: 1184 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 1243
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL--------------IIPRHYKK----- 293
L LE D+ E+ C+A ND+G+++ S +LK+ + + +K
Sbjct: 1244 L-FTKLE--DEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC 1300
Query: 294 -PRFLENLQAILSDEGAVNL-ECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL 351
P FL+ L+ I +G + E V+G P P + W+K+ ++L + II +G+ +
Sbjct: 1301 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 1360
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G Y C+A N +G + +A LL
Sbjct: 1361 IVNDPQREDSGLYICKAENMLGESTCAAELL 1391
Score = 50.0 bits (114), Expect = 1e-04
Identities = 54/217 (24%), Positives = 91/217 (41%), Gaps = 20/217 (9%)
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
SS+E E++ + +E F K P +H V+ +E + +I +
Sbjct: 1943 SSSESGTEEVAT-VKIQEAEGGFIKEDGP-MIH-TPLVDTVSEEGDIVHLTTSITNAKEV 1999
Query: 227 LWYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLD-QAEWKCVAFNDFGQSVTSCFL 283
WY +++ P DE +C +++ + L I + D Q E+ C A ND G++ TS L
Sbjct: 2000 NWYFENKLVPSDEKFKC---LQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 2056
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
++ R +E L+ L C++ P +W+K G E+ D I S
Sbjct: 2057 TVVKRAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS 2114
Query: 344 G---------QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC+ASN G + +A+L
Sbjct: 2115 SKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 2151
Score = 46.0 bits (104), Expect = 0.002
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 19/136 (13%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C A N G+ ++SA+LTV K AP ++ +E +
Sbjct: 2037 GEYVCEALNDSGKTATSAKLTVV----------------KRAAPVIKRKIEPLEVALGHL 2080
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
+FT ++ P W++ + + ES +C + + + + L+I + +D E+ C A
Sbjct: 2081 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 2139
Query: 272 NDFGQSVTSCFLKLII 287
N++G SC L +
Sbjct: 2140 NEYGS--VSCTATLTV 2153
Score = 45.6 bits (103), Expect = 0.003
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 15/91 (16%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL------TGT-- 148
P F++ L+ + +GL + FE VVG P P ++WFK+ ++L Y + +GT
Sbjct: 1302 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 1361
Query: 149 ------NSLGSYCCIAKNCMGQASSSAELTV 173
G Y C A+N +G+++ +AEL V
Sbjct: 1362 VNDPQREDSGLYICKAENMLGESTCAAELLV 1392
Score = 45.2 bits (102), Expect = 0.004
Identities = 47/211 (22%), Positives = 85/211 (40%), Gaps = 23/211 (10%)
Query: 98 PRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQL-- 145
P F++ + A ++ + + V+G P P + WF +G L P GD + L
Sbjct: 1184 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 1243
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTV-------EDIQNQLNEEEKLQLFSKNQAPK 196
T G Y C+A N G+ SA L + +D + + + L+ P
Sbjct: 1244 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 1303
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
F+ LK + P F V P P++ W+++++ + S + G +
Sbjct: 1304 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 1363
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + C A N G+S +C +L++
Sbjct: 1364 DPQREDSGLYICKAENMLGES--TCAAELLV 1392
Score = 35.1 bits (77), Expect = 4.0
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 22/228 (9%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC+V P W +DG+ L TN++ S K + A++ + E
Sbjct: 195 FECEVAN-PDSKGEWLRDGKHLPL--------TNNIRSESDGHKRRLIIAATKLDDIGEY 245
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+ +L K +A K LK++ + FT+++ P + W ++ V
Sbjct: 246 TYKVATSKTSAKL--KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV-V 302
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
ES+ + + ++ L I+ +D++ + F G+ S L + + KKP+
Sbjct: 303 LESNEKYAISVKGTIYSLRIKNCAIVDESVY---GFR-LGRLGASARLHVETVKIIKKPK 358
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
+ L+ V E V PV KW+ E+KP D HR++S
Sbjct: 359 DVTALE-----NATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVS 400
Score = 34.7 bits (76), Expect = 5.3
Identities = 79/377 (20%), Positives = 155/377 (41%), Gaps = 36/377 (9%)
Query: 2695 NIPQRD-----LAENEQQLGEDTTGSKQKVV-ELPDTIDDVSQDMIVEHLPTSEVKL-LE 2747
N PQR+ + + E LGE T ++ V+ E D D + P + L+
Sbjct: 1363 NDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLK 1422
Query: 2748 GQLLAA--EENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKSKLVEELQTIA 2805
G + A E ++ +K +++ TE ++ + IA E+ S+L Q +
Sbjct: 1423 GPAVEALDSEQEIATFVKDTILKAALITE---ENQQLSYEHIAKANELSSQLPLGAQELQ 1479
Query: 2806 DSKSQKMIEESTTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESITELNQKSSDF 2865
Q + +TRE L G P S N+ Q +++ ++ +
Sbjct: 1480 SILEQDKLTPESTREF----LCINGSIHFQPLKEPSPNLQLQIVQSQKTFSKEGILMPEE 1535
Query: 2866 TKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHETIQTLNSNLE 2925
++Q+++SD +++I + ++I + L E N P + + + +++
Sbjct: 1536 PETQAVLSD-TEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSSIEPPMHSYLTSVA 1594
Query: 2926 NEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKKDQAESSNSQTA--ENIVR 2983
E+ E+ VS E V Q+ ++ L ++S+ L + ES S +
Sbjct: 1595 EEVLSPK--EKTVSDTNREQRVTLQKQEAQSAL-ILSQSLAEGHVESLQSPDVMISQVNY 1651
Query: 2984 EIVVTSEITALETLGL------PLERSGNDGDL-VEL-------LSIETKQITVEPRATT 3029
E +V SE + E + PLE +G D + +E L++E KQ+ ++ +
Sbjct: 1652 EPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEKQVLLKEEHSD 1711
Query: 3030 YEVVAEQQVVPSGQQPV 3046
V+ Q++ S ++PV
Sbjct: 1712 NVVMPPDQIIESKREPV 1728
>AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform
protein.
Length = 1294
Score = 70.5 bits (165), Expect = 9e-11
Identities = 54/198 (27%), Positives = 91/198 (45%), Gaps = 22/198 (11%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+ P+ + L+ V + +P RF ++ P+P + WY+++Q + +C + +
Sbjct: 793 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 852
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK--------KPRFLENLQAIL 304
L I+A D A + C A ND+G + TS L + +P P + LQ +
Sbjct: 853 LLIEAFP-EDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 911
Query: 305 SDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GT 353
+ EG +C+V G V WY +++KP R+ +D T L GT
Sbjct: 912 TSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGT 969
Query: 354 YTCEASNCMGVAASSASL 371
YT ASN +G +S+A+L
Sbjct: 970 YTFVASNAVGQVSSTANL 987
Score = 56.4 bits (130), Expect = 2e-06
Identities = 36/139 (25%), Positives = 71/139 (51%), Gaps = 7/139 (5%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDI-QNQLNE--EEKLQLFSKNQAPKFVHGLKSVEAKI 208
G Y CI N G+ ++SA L+VE ++ L+E E+++++ K AP ++ +E +
Sbjct: 1159 GLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEMK-AAPVIKRKIEPLEVAL 1217
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
+FT ++ P W++ + + ES +C + + + + L+I + +D E+ C
Sbjct: 1218 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTC 1276
Query: 269 VAFNDFGQSVTSCFLKLII 287
A N++G SC L +
Sbjct: 1277 KASNEYGS--VSCTATLTV 1293
Score = 52.0 bits (119), Expect = 3e-05
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 21/202 (10%)
Query: 98 PRFMENLQAVLTEEGLVSFECKVV-GFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P+ ++ LQ V + G + C V+ G P P +SW+K+ Q L G Y L
Sbjct: 795 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 854
Query: 148 TNSLGS----YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+ Y C AKN G A++SA L+VE + ++ ++++ ++ P + L+
Sbjct: 855 IEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVY----PPAIITPLQD 909
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+P RF +V+ + + WY D+ + + SR + + L+I D+
Sbjct: 910 TVTSEGQPARFQCRVS-GTDLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDE 967
Query: 264 AEWKCVAFNDFGQSVTSCFLKL 285
+ VA N GQ ++ L L
Sbjct: 968 GTYTFVASNAVGQVSSTANLSL 989
Score = 47.6 bits (108), Expect = 7e-04
Identities = 50/208 (24%), Positives = 84/208 (40%), Gaps = 28/208 (13%)
Query: 190 SKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG 249
S +APK L+ V K + +F + + W + ++ES R L + + G
Sbjct: 1086 STGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESER--LKQSQNG 1143
Query: 250 -VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL------IIPRHYKKPRFLENLQA 302
+ FL I ++ +DQ + C+ ND G+ TS L + I+ ++ +E A
Sbjct: 1144 NIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEMKAA 1203
Query: 303 ILSDEGAVNLE----------CKVIGVPQPVLKWYKDGEELKPGDIHRIISG-------- 344
+ LE C++ P +W+K G E+ D I S
Sbjct: 1204 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 1263
Query: 345 -QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC+ASN G + +A+L
Sbjct: 1264 LRTQVVDCGEYTCKASNEYGSVSCTATL 1291
Score = 41.9 bits (94), Expect = 0.035
Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 15/91 (16%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPG---------DVYQLTG 147
P + LQ +T EG + F+C+V G V SW+ +++KP D YQL
Sbjct: 901 PAIITPLQDTVTSEGQPARFQCRVSGTDLKV-SWYSKDKKIKPSRFFRMTQFEDTYQLEI 959
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVE 174
+ G+Y +A N +GQ SS+A L++E
Sbjct: 960 AEAYPEDEGTYTFVASNAVGQVSSTANLSLE 990
Score = 35.1 bits (77), Expect = 4.0
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 22/228 (9%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
FEC+V P W +DG+ L TN++ S K + A++ + E
Sbjct: 195 FECEVAN-PDSKGEWLRDGKHLPL--------TNNIRSESDGHKRRLIIAATKLDDIGEY 245
Query: 176 IQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
+ +L K +A K LK++ + FT+++ P + W ++ V
Sbjct: 246 TYKVATSKTSAKL--KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGV-V 302
Query: 236 DESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPR 295
ES+ + + ++ L I+ +D++ + F G+ S L + + KKP+
Sbjct: 303 LESNEKYAISVKGTIYSLRIKNCAIVDESVY---GFR-LGRLGASARLHVETVKIIKKPK 358
Query: 296 FLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIIS 343
+ L+ V E V PV KW+ E+KP D HR++S
Sbjct: 359 DVTALE-----NATVAFEVSVSHDTVPV-KWFHKNVEIKPSDKHRLVS 400
>BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.
Length = 1240
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 245 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 302
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 303 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 355
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 356 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 411
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 412 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 468
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 516
Score = 44.4 bits (100), Expect = 0.007
Identities = 44/181 (24%), Positives = 73/181 (40%), Gaps = 32/181 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 511 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 556
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 557 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Query: 286 I 286
+
Sbjct: 610 L 610
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 358 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 417
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 418 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 461
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 462 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 517
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 518 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 573 EDDSLTIFGV-AERDQGSYTCVAS 595
>AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1040
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 214 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 271
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 272 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 324
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 325 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 380
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 381 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 437
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 438 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 485
Score = 44.4 bits (100), Expect = 0.007
Identities = 44/181 (24%), Positives = 73/181 (40%), Gaps = 32/181 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 420 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 479
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 480 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 525
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 526 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 578
Query: 286 I 286
+
Sbjct: 579 L 579
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 327 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 386
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 387 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 430
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 431 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 486
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 487 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 541
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 542 EDDSLTIFGV-AERDQGSYTCVAS 564
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 232 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 289
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 290 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 342
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 343 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 398
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 399 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 455
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 456 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 503
Score = 44.4 bits (100), Expect = 0.007
Identities = 44/181 (24%), Positives = 73/181 (40%), Gaps = 32/181 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 438 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 497
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 498 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 543
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 544 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 596
Query: 286 I 286
+
Sbjct: 597 L 597
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 345 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 404
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 405 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 448
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 449 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 504
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 505 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 559
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 560 EDDSLTIFGV-AERDQGSYTCVAS 582
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 239 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 296
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 297 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 349
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 350 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 405
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 406 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 462
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 463 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 510
Score = 44.8 bits (101), Expect = 0.005
Identities = 48/193 (24%), Positives = 78/193 (40%), Gaps = 34/193 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 445 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 504
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 505 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 550
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 551 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 603
Query: 286 IIPRHYKKPRFLE 298
+ +PR LE
Sbjct: 604 L--GRPDRPRDLE 614
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 352 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 411
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 412 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 455
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 456 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 511
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 512 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 566
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 567 EDDSLTIFGV-AERDQGSYTCVAS 589
>AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1240
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 245 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 302
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 303 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 355
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 356 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 411
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 412 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 468
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 516
Score = 44.4 bits (100), Expect = 0.007
Identities = 44/181 (24%), Positives = 73/181 (40%), Gaps = 32/181 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 511 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 556
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 557 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Query: 286 I 286
+
Sbjct: 610 L 610
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 358 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 417
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 418 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 461
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 462 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 517
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 518 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 573 EDDSLTIFGV-AERDQGSYTCVAS 595
>AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1347
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 245 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 302
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 303 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 355
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 356 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 411
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 412 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 468
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 516
Score = 44.4 bits (100), Expect = 0.007
Identities = 44/181 (24%), Positives = 73/181 (40%), Gaps = 32/181 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 511 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 556
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 557 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Query: 286 I 286
+
Sbjct: 610 L 610
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 358 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 417
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 418 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 461
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 462 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 517
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 518 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 573 EDDSLTIFGV-AERDQGSYTCVAS 595
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 256 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 313
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 314 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 366
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 367 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 422
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 423 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 479
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 480 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 527
Score = 44.8 bits (101), Expect = 0.005
Identities = 48/193 (24%), Positives = 78/193 (40%), Gaps = 34/193 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 462 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 521
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 522 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 567
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 568 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 620
Query: 286 IIPRHYKKPRFLE 298
+ +PR LE
Sbjct: 621 L--GRPDRPRDLE 631
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 369 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 428
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 429 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 472
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 473 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 528
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 529 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 583
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 584 EDDSLTIFGV-AERDQGSYTCVAS 606
>AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 619
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 245 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 302
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 303 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 355
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 356 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 411
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 412 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 468
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 516
Score = 44.4 bits (100), Expect = 0.007
Identities = 44/181 (24%), Positives = 73/181 (40%), Gaps = 32/181 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 510
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 511 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 556
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 557 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Query: 286 I 286
+
Sbjct: 610 L 610
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 358 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 417
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 418 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 461
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 462 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 517
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 518 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 572
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 573 EDDSLTIFGV-AERDQGSYTCVAS 595
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 53 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 110
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 111 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 163
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 164 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 219
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 220 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 276
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 277 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 324
Score = 44.8 bits (101), Expect = 0.005
Identities = 48/193 (24%), Positives = 78/193 (40%), Gaps = 34/193 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 259 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 318
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 319 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 364
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 365 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 417
Query: 286 IIPRHYKKPRFLE 298
+ +PR LE
Sbjct: 418 L--GRPDRPRDLE 428
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 166 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 225
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 226 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 269
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 270 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 325
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 326 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 380
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 381 EDDSLTIFGV-AERDQGSYTCVAS 403
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 70.1 bits (164), Expect = 1e-10
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 94 NYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
++ P+ + Q VL L+ EC G PTP ++W+K G +L P D + N
Sbjct: 309 SFMYPQGTASSQMVLRGMDLL-LECIASGVPTPDIAWYKKGGDL-PSDKAKFENFNKALR 366
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
+++ G+ A + I++ ++ K AP ++ K++ E R
Sbjct: 367 ITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILAPGEDGR 419
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAF 271
+ P+P++ W + +P+ +S+ + +E G + F D Q +A ++C
Sbjct: 420 LVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTIIFRDTQ---ISSRAVYQCNTS 475
Query: 272 NDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N+ G + + F+ ++ +P PR + ++ IL + L+C G P P L+W+K+G
Sbjct: 476 NEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--TRLDCPFFGSPIPTLRWFKNG 532
Query: 331 E--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMGVAASSASL 371
+ L G+ H +G + G YTC A+N +G A + L
Sbjct: 533 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 580
Score = 44.8 bits (101), Expect = 0.005
Identities = 48/193 (24%), Positives = 78/193 (40%), Gaps = 34/193 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 515 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 574
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 575 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 620
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 621 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 673
Query: 286 IIPRHYKKPRFLE 298
+ +PR LE
Sbjct: 674 L--GRPDRPRDLE 684
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELKP----------GD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 422 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 481
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 482 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 525
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 526 LRWFKNGQGSNLDGGNYHV--YENGS--LEIKMIRKEDQGIYTCVATNILGKAENQVRLE 581
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 582 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 636
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 637 EDDSLTIFGV-AERDQGSYTCVAS 659
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 68.9 bits (161), Expect = 3e-10
Identities = 77/302 (25%), Positives = 122/302 (40%), Gaps = 50/302 (16%)
Query: 97 KPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F++ +T + F+C+ G P P + W KD EL P Y++ ++L
Sbjct: 222 RPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDHTLKIRK 280
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
GSY C+A+N +G+A +SA LTV Q+ E P FV +
Sbjct: 281 VTAGDMGSYTCVAENMVGKAEASATLTV-----QVGSEP----------PHFVVKPRDQV 325
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDD--------QPVDESSRCHLGKEERGVFFLDIQA 257
+ F + P+P++ W R+ QP SSR + + L I
Sbjct: 326 VALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITN 381
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN--LQAILSDEGAVNLECK 315
++ D + C N G +T +L++ + P + + ++ +G L C
Sbjct: 382 VQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCV 441
Query: 316 VIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAAS 367
G P P + W KDG + D RI ++G + G YTC AS G A
Sbjct: 442 ATGSPVPTILWRKDGVLVSTQD-SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATW 500
Query: 368 SA 369
SA
Sbjct: 501 SA 502
Score = 64.5 bits (150), Expect = 6e-09
Identities = 76/303 (25%), Positives = 127/303 (41%), Gaps = 54/303 (17%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELK-----PGDVYQLTGTNSL 151
PR +E+ ++ +G + CK G PTP + W+K G+ ++ P L + SL
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 152 ---------------GSYCCIAKNCMGQA-SSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
G Y C+A+N +G+A S +A L V +++ F +N +
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD---------FRQNPSD 139
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDI 255
V + + P PEP++ W +D P+D+ + + L I
Sbjct: 140 VMVVVGEPAVMECQPPRGH-------PEPTISWKKDGSPLDDKDERITIRGGK----LMI 188
Query: 256 QALEFLDQAEWKCVAFNDFGQSVTSCFLKLII--PRHYKKPRFLENLQAILSDEGAVNLE 313
D ++ CV N G+ + ++ P K+P NL A+ D+ A +
Sbjct: 189 TYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP---SNL-AVTVDDSA-EFK 243
Query: 314 CKVIGVPQPVLKWYKDGEELKPG-----DIHRIISGQDGTCSLGTYTCEASNCMGVAASS 368
C+ G P P ++W KD EL D H + + +G+YTC A N +G A +S
Sbjct: 244 CEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEAS 303
Query: 369 ASL 371
A+L
Sbjct: 304 ATL 306
Score = 62.5 bits (145), Expect = 2e-08
Identities = 74/299 (24%), Positives = 122/299 (40%), Gaps = 49/299 (16%)
Query: 51 LLFVSLANGWTDLANFGLELFVEVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTE 110
L F+ + +G + G+ +V V R + + HN+ V + F +N V+
Sbjct: 88 LFFLRIVHGRKSRPDEGV--YVCVARNYLGEAVSHNASLEVA--ILRDDFRQNPSDVMVV 143
Query: 111 EGLVS-FECKVV-GFPTPVLSWFKDGQELKPGD----------VYQLTGTNSLGSYCCIA 158
G + EC+ G P P +SW KDG L D + T + G Y C+
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVG 203
Query: 159 KNCMGQASSS-AELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
N +G+ S AELTV + P FV ++ +D+ F +
Sbjct: 204 TNMVGERESEVAELTVLE------------------RPSFVKRPSNLAVTVDDSAEFKCE 245
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
P P++ W +DD + +S E R L I+ + D + CVA N G++
Sbjct: 246 ARGDPVPTVRWRKDDGELPKSRY-----EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 278 VTSCFLKLII---PRHYK-KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
S L + + P H+ KPR +++ V +C+ G PQP + W ++G +
Sbjct: 301 EASATLTVQVGSEPPHFVVKPR-----DQVVALGRTVTFQCEATGNPQPAIFWRREGSQ 354
Score = 42.3 bits (95), Expect = 0.027
Identities = 50/192 (26%), Positives = 79/192 (41%), Gaps = 17/192 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD---ESSRCHLGKEERG-V 250
P+ V + EP K P P++ WY+ + V+ + R H G +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 251 FFLDIQ--ALEFLDQAEWKCVAFNDFGQSVT-SCFLKLIIPRHYKKPRFLENLQAILSDE 307
FFL I D+ + CVA N G++V+ + L++ I R + + + ++ E
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVM--VVVGE 146
Query: 308 GAVNLECKVI-GVPQPVLKWYKDGEELKPGDIHRIISG------QDGTCSLGTYTCEASN 360
AV +EC+ G P+P + W KDG L D I G G Y C +N
Sbjct: 147 PAV-MECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTN 205
Query: 361 CMGVAASSASLL 372
+G S + L
Sbjct: 206 MVGERESEVAEL 217
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 68.9 bits (161), Expect = 3e-10
Identities = 77/302 (25%), Positives = 122/302 (40%), Gaps = 50/302 (16%)
Query: 97 KPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F++ +T + F+C+ G P P + W KD EL P Y++ ++L
Sbjct: 222 RPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDHTLKIRK 280
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
GSY C+A+N +G+A +SA LTV Q+ E P FV +
Sbjct: 281 VTAGDMGSYTCVAENMVGKAEASATLTV-----QVGSEP----------PHFVVKPRDQV 325
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDD--------QPVDESSRCHLGKEERGVFFLDIQA 257
+ F + P+P++ W R+ QP SSR + + L I
Sbjct: 326 VALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITN 381
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN--LQAILSDEGAVNLECK 315
++ D + C N G +T +L++ + P + + ++ +G L C
Sbjct: 382 VQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCV 441
Query: 316 VIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAAS 367
G P P + W KDG + D RI ++G + G YTC AS G A
Sbjct: 442 ATGSPVPTILWRKDGVLVSTQD-SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATW 500
Query: 368 SA 369
SA
Sbjct: 501 SA 502
Score = 64.9 bits (151), Expect = 4e-09
Identities = 76/303 (25%), Positives = 127/303 (41%), Gaps = 54/303 (17%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELK-----PGDVYQLTGTNSL 151
PR +E+ ++ +G + CK G PTP + W+K G+ ++ P L + SL
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 152 ---------------GSYCCIAKNCMGQA-SSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
G Y C+A+N +G+A S +A L V +++ F +N +
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD---------FRQNPSD 139
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDI 255
V + + P PEP++ W +D P+D+ + + L I
Sbjct: 140 VMVAVGEPAVMECQPPRGH-------PEPTISWKKDGSPLDDKDERITIRGGK----LMI 188
Query: 256 QALEFLDQAEWKCVAFNDFGQSVTSCFLKLII--PRHYKKPRFLENLQAILSDEGAVNLE 313
D ++ CV N G+ + ++ P K+P NL A+ D+ A +
Sbjct: 189 TYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP---SNL-AVTVDDSA-EFK 243
Query: 314 CKVIGVPQPVLKWYKDGEELKPG-----DIHRIISGQDGTCSLGTYTCEASNCMGVAASS 368
C+ G P P ++W KD EL D H + + +G+YTC A N +G A +S
Sbjct: 244 CEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEAS 303
Query: 369 ASL 371
A+L
Sbjct: 304 ATL 306
Score = 62.9 bits (146), Expect = 2e-08
Identities = 74/299 (24%), Positives = 122/299 (40%), Gaps = 49/299 (16%)
Query: 51 LLFVSLANGWTDLANFGLELFVEVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTE 110
L F+ + +G + G+ +V V R + + HN+ V + F +N V+
Sbjct: 88 LFFLRIVHGRKSRPDEGV--YVCVARNYLGEAVSHNASLEVA--ILRDDFRQNPSDVMVA 143
Query: 111 EGLVS-FECKVV-GFPTPVLSWFKDGQELKPGD----------VYQLTGTNSLGSYCCIA 158
G + EC+ G P P +SW KDG L D + T + G Y C+
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVG 203
Query: 159 KNCMGQASSS-AELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
N +G+ S AELTV + P FV ++ +D+ F +
Sbjct: 204 TNMVGERESEVAELTVLE------------------RPSFVKRPSNLAVTVDDSAEFKCE 245
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
P P++ W +DD + +S E R L I+ + D + CVA N G++
Sbjct: 246 ARGDPVPTVRWRKDDGELPKSRY-----EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 278 VTSCFLKLII---PRHYK-KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
S L + + P H+ KPR +++ V +C+ G PQP + W ++G +
Sbjct: 301 EASATLTVQVGSEPPHFVVKPR-----DQVVALGRTVTFQCEATGNPQPAIFWRREGSQ 354
Score = 43.6 bits (98), Expect = 0.011
Identities = 51/192 (26%), Positives = 79/192 (41%), Gaps = 17/192 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD---ESSRCHLGKEERG-V 250
P+ V + EP K P P++ WY+ + V+ + R H G +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 251 FFLDIQ--ALEFLDQAEWKCVAFNDFGQSVT-SCFLKLIIPRHYKKPRFLENLQAILSDE 307
FFL I D+ + CVA N G++V+ + L++ I R + + + A+ E
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV--GE 146
Query: 308 GAVNLECKVI-GVPQPVLKWYKDGEELKPGDIHRIISG------QDGTCSLGTYTCEASN 360
AV +EC+ G P+P + W KDG L D I G G Y C +N
Sbjct: 147 PAV-MECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTN 205
Query: 361 CMGVAASSASLL 372
+G S + L
Sbjct: 206 MVGERESEVAEL 217
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 68.9 bits (161), Expect = 3e-10
Identities = 77/302 (25%), Positives = 122/302 (40%), Gaps = 50/302 (16%)
Query: 97 KPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F++ +T + F+C+ G P P + W KD EL P Y++ ++L
Sbjct: 222 RPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDHTLKIRK 280
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
GSY C+A+N +G+A +SA LTV Q+ E P FV +
Sbjct: 281 VTAGDMGSYTCVAENMVGKAEASATLTV-----QVGSEP----------PHFVVKPRDQV 325
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDD--------QPVDESSRCHLGKEERGVFFLDIQA 257
+ F + P+P++ W R+ QP SSR + + L I
Sbjct: 326 VALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITN 381
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN--LQAILSDEGAVNLECK 315
++ D + C N G +T +L++ + P + + ++ +G L C
Sbjct: 382 VQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCV 441
Query: 316 VIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAAS 367
G P P + W KDG + D RI ++G + G YTC AS G A
Sbjct: 442 ATGSPVPTILWRKDGVLVSTQD-SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATW 500
Query: 368 SA 369
SA
Sbjct: 501 SA 502
Score = 64.9 bits (151), Expect = 4e-09
Identities = 76/303 (25%), Positives = 127/303 (41%), Gaps = 54/303 (17%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELK-----PGDVYQLTGTNSL 151
PR +E+ ++ +G + CK G PTP + W+K G+ ++ P L + SL
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 152 ---------------GSYCCIAKNCMGQA-SSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
G Y C+A+N +G+A S +A L V +++ F +N +
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD---------FRQNPSD 139
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDI 255
V + + P PEP++ W +D P+D+ + + L I
Sbjct: 140 VMVAVGEPAVMECQPPRGH-------PEPTISWKKDGSPLDDKDERITIRGGK----LMI 188
Query: 256 QALEFLDQAEWKCVAFNDFGQSVTSCFLKLII--PRHYKKPRFLENLQAILSDEGAVNLE 313
D ++ CV N G+ + ++ P K+P NL A+ D+ A +
Sbjct: 189 TYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP---SNL-AVTVDDSA-EFK 243
Query: 314 CKVIGVPQPVLKWYKDGEELKPG-----DIHRIISGQDGTCSLGTYTCEASNCMGVAASS 368
C+ G P P ++W KD EL D H + + +G+YTC A N +G A +S
Sbjct: 244 CEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEAS 303
Query: 369 ASL 371
A+L
Sbjct: 304 ATL 306
Score = 62.9 bits (146), Expect = 2e-08
Identities = 74/299 (24%), Positives = 122/299 (40%), Gaps = 49/299 (16%)
Query: 51 LLFVSLANGWTDLANFGLELFVEVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTE 110
L F+ + +G + G+ +V V R + + HN+ V + F +N V+
Sbjct: 88 LFFLRIVHGRKSRPDEGV--YVCVARNYLGEAVSHNASLEVA--ILRDDFRQNPSDVMVA 143
Query: 111 EGLVS-FECKVV-GFPTPVLSWFKDGQELKPGD----------VYQLTGTNSLGSYCCIA 158
G + EC+ G P P +SW KDG L D + T + G Y C+
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVG 203
Query: 159 KNCMGQASSS-AELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
N +G+ S AELTV + P FV ++ +D+ F +
Sbjct: 204 TNMVGERESEVAELTVLE------------------RPSFVKRPSNLAVTVDDSAEFKCE 245
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
P P++ W +DD + +S E R L I+ + D + CVA N G++
Sbjct: 246 ARGDPVPTVRWRKDDGELPKSRY-----EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 278 VTSCFLKLII---PRHYK-KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
S L + + P H+ KPR +++ V +C+ G PQP + W ++G +
Sbjct: 301 EASATLTVQVGSEPPHFVVKPR-----DQVVALGRTVTFQCEATGNPQPAIFWRREGSQ 354
Score = 43.6 bits (98), Expect = 0.011
Identities = 51/192 (26%), Positives = 79/192 (41%), Gaps = 17/192 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD---ESSRCHLGKEERG-V 250
P+ V + EP K P P++ WY+ + V+ + R H G +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 251 FFLDIQ--ALEFLDQAEWKCVAFNDFGQSVT-SCFLKLIIPRHYKKPRFLENLQAILSDE 307
FFL I D+ + CVA N G++V+ + L++ I R + + + A+ E
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV--GE 146
Query: 308 GAVNLECKVI-GVPQPVLKWYKDGEELKPGDIHRIISG------QDGTCSLGTYTCEASN 360
AV +EC+ G P+P + W KDG L D I G G Y C +N
Sbjct: 147 PAV-MECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTN 205
Query: 361 CMGVAASSASLL 372
+G S + L
Sbjct: 206 MVGERESEVAEL 217
>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B
protein.
Length = 1960
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 17/189 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F L A++ E + +V P+P + WY+D + V L ++ G L
Sbjct: 6 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 65
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLE 313
+ +L +D ++ C A + G T + + +P PRF+ ++A EG
Sbjct: 66 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 120
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC----------SLGTYTCEASNCM 362
C + G P P ++WYKDG L G+ + +S + G LG Y CE N +
Sbjct: 121 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 180
Query: 363 GVAASSASL 371
G A +SA L
Sbjct: 181 GSARASAEL 189
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
+R P F E L E G V C+V G P PV+SW+KDG+ ++ D + + + GS
Sbjct: 3 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGS 61
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
I + G S + K+ + P+FV+ +++ E +
Sbjct: 62 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV---QVPPRFVNKVRASPFVEGEDAQ 118
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER-GVFFLDIQALEFLDQAEWKCVAFN 272
FT + P P + WY+D + ++ E R G+ L I+A D ++C N
Sbjct: 119 FTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 178
Query: 273 DFGQSVTSCFLKLIIP 288
G + S L++ P
Sbjct: 179 RLGSARASAELRIQSP 194
Score = 54.8 bits (126), Expect = 5e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
++ P F E L ++ G V L C+V G P+PV+ WYKDG+ ++ H +I DG+C
Sbjct: 3 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 62
Query: 350 SL----------GTYTCEASNCMGVAASSASLL 372
+L G Y C A++ G ++ +L
Sbjct: 63 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKIL 95
Score = 40.3 bits (90), Expect = 0.11
Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 14/104 (13%)
Query: 96 RKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL 145
R P ++ V + G FE + G P P ++W+KD +L + G Y L
Sbjct: 347 RPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSL 406
Query: 146 ----TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
+ G Y C+A+N GQ AEL V N+ + E++
Sbjct: 407 VLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQ 450
Score = 37.1 bits (82), Expect = 1.00
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 15/87 (17%)
Query: 297 LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC------- 349
+E++QA G E + G PQP + WYKD +L D R+ Q+GT
Sbjct: 355 IEDVQA--QTGGTAQFEAIIEGDPQPSVTWYKDSVQLV--DSTRLSQQQEGTTYSLVLRH 410
Query: 350 ----SLGTYTCEASNCMGVAASSASLL 372
G YTC A N G A LL
Sbjct: 411 VASKDAGVYTCLAQNTGGQVLCKAELL 437
Score = 35.5 bits (78), Expect = 3.0
Identities = 22/88 (25%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALE 259
++ V+A+ +F + P+PS+ WY+D + +S+R L +++ G + L ++ +
Sbjct: 355 IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR--LSQQQEGTTYSLVLRHVA 412
Query: 260 FLDQAEWKCVAFNDFGQSVTSCFLKLII 287
D + C+A N GQ + C +L++
Sbjct: 413 SKDAGVYTCLAQNTGGQVL--CKAELLV 438
Score = 34.3 bits (75), Expect = 7.0
Identities = 22/97 (22%), Positives = 38/97 (39%)
Query: 188 LFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEE 247
L S ++AP F+ L + + +V+ P W +D P++ SSR +
Sbjct: 1448 LKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATL 1507
Query: 248 RGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
+ L I + D + C N G T+ L+
Sbjct: 1508 KNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 1544
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 17/189 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F L A++ E + +V P+P + WY+D + V L ++ G L
Sbjct: 630 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 689
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLE 313
+ +L +D ++ C A + G T + + +P PRF+ ++A EG
Sbjct: 690 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 744
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC----------SLGTYTCEASNCM 362
C + G P P ++WYKDG L G+ + +S + G LG Y CE N +
Sbjct: 745 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 804
Query: 363 GVAASSASL 371
G A +SA L
Sbjct: 805 GSARASAEL 813
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
+R P F E L E G V C+V G P PV+SW+KDG+ ++ D + + + GS
Sbjct: 627 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGS 685
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
I + G S + K+ + P+FV+ +++ E +
Sbjct: 686 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV---QVPPRFVNKVRASPFVEGEDAQ 742
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER-GVFFLDIQALEFLDQAEWKCVAFN 272
FT + P P + WY+D + ++ E R G+ L I+A D ++C N
Sbjct: 743 FTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 802
Query: 273 DFGQSVTSCFLKLIIP 288
G + S L++ P
Sbjct: 803 RLGSARASAELRIQSP 818
Score = 54.8 bits (126), Expect = 5e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
++ P F E L ++ G V L C+V G P+PV+ WYKDG+ ++ H +I DG+C
Sbjct: 627 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 686
Query: 350 SL----------GTYTCEASNCMGVAASSASLL 372
+L G Y C A++ G ++ +L
Sbjct: 687 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKIL 719
Score = 40.3 bits (90), Expect = 0.11
Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 14/104 (13%)
Query: 96 RKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL 145
R P ++ V + G FE + G P P ++W+KD +L + G Y L
Sbjct: 971 RPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSL 1030
Query: 146 ----TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
+ G Y C+A+N GQ AEL V N+ + E++
Sbjct: 1031 VLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQ 1074
Score = 37.1 bits (82), Expect = 1.00
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 15/87 (17%)
Query: 297 LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC------- 349
+E++QA G E + G PQP + WYKD +L D R+ Q+GT
Sbjct: 979 IEDVQA--QTGGTAQFEAIIEGDPQPSVTWYKDSVQLV--DSTRLSQQQEGTTYSLVLRH 1034
Query: 350 ----SLGTYTCEASNCMGVAASSASLL 372
G YTC A N G A LL
Sbjct: 1035 VASKDAGVYTCLAQNTGGQVLCKAELL 1061
Score = 35.5 bits (78), Expect = 3.0
Identities = 22/88 (25%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALE 259
++ V+A+ +F + P+PS+ WY+D + +S+R L +++ G + L ++ +
Sbjct: 979 IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR--LSQQQEGTTYSLVLRHVA 1036
Query: 260 FLDQAEWKCVAFNDFGQSVTSCFLKLII 287
D + C+A N GQ + C +L++
Sbjct: 1037 SKDAGVYTCLAQNTGGQVL--CKAELLV 1062
Score = 34.3 bits (75), Expect = 7.0
Identities = 22/97 (22%), Positives = 38/97 (39%)
Query: 188 LFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEE 247
L S ++AP F+ L + + +V+ P W +D P++ SSR +
Sbjct: 2072 LKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATL 2131
Query: 248 RGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
+ L I + D + C N G T+ L+
Sbjct: 2132 KNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 17/189 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F L A++ E + +V P+P + WY+D + V L ++ G L
Sbjct: 630 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 689
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLE 313
+ +L +D ++ C A + G T + + +P PRF+ ++A EG
Sbjct: 690 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 744
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC----------SLGTYTCEASNCM 362
C + G P P ++WYKDG L G+ + +S + G LG Y CE N +
Sbjct: 745 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 804
Query: 363 GVAASSASL 371
G A +SA L
Sbjct: 805 GSARASAEL 813
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
+R P F E L E G V C+V G P PV+SW+KDG+ ++ D + + + GS
Sbjct: 627 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGS 685
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
I + G S + K+ + P+FV+ +++ E +
Sbjct: 686 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV---QVPPRFVNKVRASPFVEGEDAQ 742
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER-GVFFLDIQALEFLDQAEWKCVAFN 272
FT + P P + WY+D + ++ E R G+ L I+A D ++C N
Sbjct: 743 FTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 802
Query: 273 DFGQSVTSCFLKLIIP 288
G + S L++ P
Sbjct: 803 RLGSARASAELRIQSP 818
Score = 54.8 bits (126), Expect = 5e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
++ P F E L ++ G V L C+V G P+PV+ WYKDG+ ++ H +I DG+C
Sbjct: 627 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 686
Query: 350 SL----------GTYTCEASNCMGVAASSASLL 372
+L G Y C A++ G ++ +L
Sbjct: 687 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKIL 719
Score = 40.3 bits (90), Expect = 0.11
Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 14/104 (13%)
Query: 96 RKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL 145
R P ++ V + G FE + G P P ++W+KD +L + G Y L
Sbjct: 971 RPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSL 1030
Query: 146 ----TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
+ G Y C+A+N GQ AEL V N+ + E++
Sbjct: 1031 VLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQ 1074
Score = 37.1 bits (82), Expect = 1.00
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 15/87 (17%)
Query: 297 LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC------- 349
+E++QA G E + G PQP + WYKD +L D R+ Q+GT
Sbjct: 979 IEDVQA--QTGGTAQFEAIIEGDPQPSVTWYKDSVQLV--DSTRLSQQQEGTTYSLVLRH 1034
Query: 350 ----SLGTYTCEASNCMGVAASSASLL 372
G YTC A N G A LL
Sbjct: 1035 VASKDAGVYTCLAQNTGGQVLCKAELL 1061
Score = 35.5 bits (78), Expect = 3.0
Identities = 22/88 (25%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALE 259
++ V+A+ +F + P+PS+ WY+D + +S+R L +++ G + L ++ +
Sbjct: 979 IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR--LSQQQEGTTYSLVLRHVA 1036
Query: 260 FLDQAEWKCVAFNDFGQSVTSCFLKLII 287
D + C+A N GQ + C +L++
Sbjct: 1037 SKDAGVYTCLAQNTGGQVL--CKAELLV 1062
Score = 34.3 bits (75), Expect = 7.0
Identities = 22/97 (22%), Positives = 38/97 (39%)
Query: 188 LFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEE 247
L S ++AP F+ L + + +V+ P W +D P++ SSR +
Sbjct: 2072 LKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATL 2131
Query: 248 RGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
+ L I + D + C N G T+ L+
Sbjct: 2132 KNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168
>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
Length = 1020
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 17/189 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F L A++ E + +V P+P + WY+D + V L ++ G L
Sbjct: 414 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 473
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLE 313
+ +L +D ++ C A + G T + + +P PRF+ ++A EG
Sbjct: 474 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 528
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC----------SLGTYTCEASNCM 362
C + G P P ++WYKDG L G+ + +S + G LG Y CE N +
Sbjct: 529 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 588
Query: 363 GVAASSASL 371
G A +SA L
Sbjct: 589 GSARASAEL 597
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
+R P F E L E G V C+V G P PV+SW+KDG+ ++ D + + + GS
Sbjct: 411 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGS 469
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
I + G S + K+ + P+FV+ +++ E +
Sbjct: 470 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV---QVPPRFVNKVRASPFVEGEDAQ 526
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER-GVFFLDIQALEFLDQAEWKCVAFN 272
FT + P P + WY+D + ++ E R G+ L I+A D ++C N
Sbjct: 527 FTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 586
Query: 273 DFGQSVTSCFLKLIIP 288
G + S L++ P
Sbjct: 587 RLGSARASAELRIQSP 602
Score = 54.8 bits (126), Expect = 5e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
++ P F E L ++ G V L C+V G P+PV+ WYKDG+ ++ H +I DG+C
Sbjct: 411 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 470
Query: 350 SL----------GTYTCEASNCMGVAASSASLL 372
+L G Y C A++ G ++ +L
Sbjct: 471 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKIL 503
>AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS
protein.
Length = 475
Score = 68.9 bits (161), Expect = 3e-10
Identities = 46/154 (29%), Positives = 73/154 (47%), Gaps = 6/154 (3%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P+P + W++D PVD S+ K+ R L I++ E DQ +++CVA N G +S
Sbjct: 36 PDPEITWFKDFLPVDPSASNGRIKQLRSGA-LQIESSEETDQGKYECVATNSAGVRYSSP 94
Query: 282 FLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD--- 337
L + PRF + + + G VN+ C +G P P +KW + E+L P D
Sbjct: 95 -ANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMP 153
Query: 338 IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
+ R + YTC A + +GV + A +
Sbjct: 154 VGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQI 187
Score = 43.6 bits (98), Expect = 0.011
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 7/72 (9%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGD-------VYQLTGTNSLGSYCCIAKNCMGQ 164
G V+ C VG P P + W + ++L P D V +LT +Y C+A + +G
Sbjct: 121 GNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV 180
Query: 165 ASSSAELTVEDI 176
+ A++TV+ +
Sbjct: 181 IEAVAQITVKSL 192
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 68.9 bits (161), Expect = 3e-10
Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 17/189 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F L A++ E + +V P+P + WY+D + V L ++ G L
Sbjct: 630 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 689
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLE 313
+ +L +D ++ C A + G T + + +P PRF+ ++A EG
Sbjct: 690 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 744
Query: 314 CKVIGVPQPVLKWYKDGEELKPGDIHRIIS-GQDGTC----------SLGTYTCEASNCM 362
C + G P P ++WYKDG L G+ + +S + G LG Y CE N +
Sbjct: 745 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 804
Query: 363 GVAASSASL 371
G A +SA L
Sbjct: 805 GSARASAEL 813
Score = 63.3 bits (147), Expect = 1e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 6/196 (3%)
Query: 95 YRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
+R P F E L E G V C+V G P PV+SW+KDG+ ++ D + + + GS
Sbjct: 627 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGS 685
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
I + G S + K+ + P+FV+ +++ E +
Sbjct: 686 CALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV---QVPPRFVNKVRASPFVEGEDAQ 742
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER-GVFFLDIQALEFLDQAEWKCVAFN 272
FT + P P + WY+D + ++ E R G+ L I+A D ++C N
Sbjct: 743 FTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 802
Query: 273 DFGQSVTSCFLKLIIP 288
G + S L++ P
Sbjct: 803 RLGSARASAELRIQSP 818
Score = 54.8 bits (126), Expect = 5e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
++ P F E L ++ G V L C+V G P+PV+ WYKDG+ ++ H +I DG+C
Sbjct: 627 WRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSC 686
Query: 350 SL----------GTYTCEASNCMGVAASSASLL 372
+L G Y C A++ G ++ +L
Sbjct: 687 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKIL 719
Score = 40.3 bits (90), Expect = 0.11
Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 14/104 (13%)
Query: 96 RKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL 145
R P ++ V + G FE + G P P ++W+KD +L + G Y L
Sbjct: 971 RPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSL 1030
Query: 146 ----TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
+ G Y C+A+N GQ AEL V N+ + E++
Sbjct: 1031 VLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQ 1074
Score = 37.1 bits (82), Expect = 1.00
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 15/87 (17%)
Query: 297 LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC------- 349
+E++QA G E + G PQP + WYKD +L D R+ Q+GT
Sbjct: 979 IEDVQA--QTGGTAQFEAIIEGDPQPSVTWYKDSVQLV--DSTRLSQQQEGTTYSLVLRH 1034
Query: 350 ----SLGTYTCEASNCMGVAASSASLL 372
G YTC A N G A LL
Sbjct: 1035 VASKDAGVYTCLAQNTGGQVLCKAELL 1061
Score = 35.5 bits (78), Expect = 3.0
Identities = 22/88 (25%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALE 259
++ V+A+ +F + P+PS+ WY+D + +S+R L +++ G + L ++ +
Sbjct: 979 IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR--LSQQQEGTTYSLVLRHVA 1036
Query: 260 FLDQAEWKCVAFNDFGQSVTSCFLKLII 287
D + C+A N GQ + C +L++
Sbjct: 1037 SKDAGVYTCLAQNTGGQVL--CKAELLV 1062
Score = 34.3 bits (75), Expect = 7.0
Identities = 22/97 (22%), Positives = 38/97 (39%)
Query: 188 LFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEE 247
L S ++AP F+ L + + +V+ P W +D P++ SSR +
Sbjct: 2072 LKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATL 2131
Query: 248 RGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
+ L I + D + C N G T+ L+
Sbjct: 2132 KNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLR 2168
>BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1287
Score = 68.5 bits (160), Expect = 4e-10
Identities = 62/223 (27%), Positives = 96/223 (43%), Gaps = 31/223 (13%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD----VYQLTGTNSL-----GSYCCIAKNCMGQ 164
V+ EC V G P P + W KDGQ++ P +Y T+S+ G+Y C+A N G
Sbjct: 239 VTLECVVSGVPAPQVYWLKDGQDIAPESNWRRLYSHLATDSVDPADSGNYSCMAGNKSGD 298
Query: 165 ASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEP 224
V+ + +N E + SK GL+ + FT V P P
Sbjct: 299 --------VKYVTYMVNVLEHASI-SK--------GLQDQIVSLGATVHFTCDVHGNPAP 341
Query: 225 SLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
+ W+ + QP+ S+R HL L I + D ++CVA N G ++ L+
Sbjct: 342 NCTWFHNAQPIHPSAR-HLTAGNG----LKISGVTVEDVGMYQCVADNGIGFMHSTGRLE 396
Query: 285 LIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
+ +K + A ++D V L C G+P PV++WY
Sbjct: 397 IENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRWY 439
Score = 49.6 bits (113), Expect = 2e-04
Identities = 75/285 (26%), Positives = 115/285 (40%), Gaps = 44/285 (15%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG----DVYQLTGT----NS--L 151
E L AV G V C T + SW +G+ L ++Q T T NS L
Sbjct: 34 EPLSAVQKLGGPVVLHCSAQPVTTRI-SWLHNGKTLDGNLEHIKIHQGTLTILSLNSSLL 92
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C+A N +G S + K + ++ ++ F+ G + E+
Sbjct: 93 GYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTKHVITAEEKSAGFI-GCRVPESNPKAE 151
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
R+ I+ W ++ S+ +L + L++ +LE D+ +KC A+
Sbjct: 152 VRYKIRGK--------W------LEHSTENYLILPSGNLQILNV-SLE--DKGSYKCAAY 194
Query: 272 NDFGQS--VTSCFLKLIIPR------HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPV 323
N V KL++ R H P + L A+LS V LEC V GVP P
Sbjct: 195 NPVTHQLKVEPIGRKLLVSRPSSDDVHILHPTHSQAL-AVLS-RSPVTLECVVSGVPAPQ 252
Query: 324 LKWYKDGEELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMG 363
+ W KDG+++ P R + T S+ G Y+C A N G
Sbjct: 253 VYWLKDGQDIAPESNWRRLYSHLATDSVDPADSGNYSCMAGNKSG 297
Score = 37.9 bits (84), Expect = 0.57
Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 15/156 (9%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P + W +D Q + S R L +++ D + C+A N G
Sbjct: 249 PAPQVYWLKDGQDIAPESNWR-----RLYSHLATDSVDPADSGNYSCMAGNKSGDVKYVT 303
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ ++ H + L++ I+S V+ C V G P P W+ + + + P H +
Sbjct: 304 YMVNVL-EHASISKGLQD--QIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARH-L 359
Query: 342 ISGQDGTCS------LGTYTCEASNCMGVAASSASL 371
+G S +G Y C A N +G S+ L
Sbjct: 360 TAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRL 395
>BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion
molecule 1 protein.
Length = 858
Score = 68.1 bits (159), Expect = 5e-10
Identities = 71/304 (23%), Positives = 130/304 (42%), Gaps = 37/304 (12%)
Query: 78 FKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL 137
FK I++I N PT+ + N A L + V+ C GFP P +SW KDG+++
Sbjct: 201 FKDIQVIVNVPPTIQARQN----IVNATANLGQS--VTLVCDAEGFPEPTMSWTKDGEQI 254
Query: 138 KPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK---LQLFSKNQA 194
+ + + + S I K + AE + +N+ E++ L++F+K
Sbjct: 255 EQEEDDEKYIFSDDSSQLTIKKV---DKNDEAEY-ICIAENKAGEQDATIHLKVFAK--- 307
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEER------ 248
PK + +++E T + + P PS+ W + + + + E+
Sbjct: 308 PKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDG 367
Query: 249 --------GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENL 300
V L ++++++ D E+ C A N GQ S +L++ Y P+ L+
Sbjct: 368 HMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV----QY-APK-LQGP 421
Query: 301 QAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCEAS 359
A+ + EG VN+ C+V P + W++DG+ L + I + S T ++
Sbjct: 422 VAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSE 481
Query: 360 NCMG 363
N G
Sbjct: 482 NDFG 485
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 67.3 bits (157), Expect = 8e-10
Identities = 68/282 (24%), Positives = 113/282 (40%), Gaps = 26/282 (9%)
Query: 94 NYRKPRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
N +PR Q A +T V F C+ G P P + W ++ EL +L N L
Sbjct: 259 NCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRL---NLLD 315
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEE-KLQLFSKNQAPKFVHGLKSVEAKIDEP 211
+ +N + +++ ++ +E L+ F P FV ++ E + E
Sbjct: 316 DGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGES 375
Query: 212 FRFTIKVAIPPEPSLLWYRDDQ-PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
P P + W R D+ P+ R ++ G++ IQ + D E+ C A
Sbjct: 376 VTLECSATGHPPPRISWTRGDRTPLPVDPRVNI-TPSGGLY---IQNVVQGDSGEYACSA 431
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKD 329
N+ + F+ + P+F Q + EG V+ +C+ G P PV+ W K
Sbjct: 432 TNNIDSVHATAFIIV-----QALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKG 486
Query: 330 GEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
G +L H ++S GT + G Y C+A N +G
Sbjct: 487 GSQLSVDRRHLVLS--SGTLRISGVALHDQGQYECQAVNIIG 526
Score = 54.4 bits (125), Expect = 6e-06
Identities = 51/202 (25%), Positives = 78/202 (38%), Gaps = 31/202 (15%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P+F Q + EG V F+C+ G P PV++W K G +L + + + +L
Sbjct: 450 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGV 509
Query: 152 -----GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
G Y C A N +G A LTV+ P F
Sbjct: 510 ALHDQGQYECQAVNIIGSQKVVAHLTVQP----------------RVTPVFASIPSDTTV 553
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
++ + PEP++ W +D V ES + H+ E FL I + D +
Sbjct: 554 EVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG----FLTINDVGPADAGRY 609
Query: 267 KCVAFNDFGQSVTSCFLKLIIP 288
+CVA N G + S L + +P
Sbjct: 610 ECVARNTIGSASVSMVLSVNVP 631
Score = 50.8 bits (116), Expect = 8e-05
Identities = 69/279 (24%), Positives = 109/279 (39%), Gaps = 27/279 (9%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC-IAKN 160
+N + ++ E V+ EC G P P +SW + + P D ++ T S G Y + +
Sbjct: 366 QNTEVLVGES--VTLECSATGHPPPRISWTRGDRTPLPVDP-RVNITPSGGLYIQNVVQG 422
Query: 161 CMGQASSSAELTVEDIQ-NQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVA 219
G+ + SA ++ + + L F+ + V ++V+ F +
Sbjct: 423 DSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVD--------FQCEAK 474
Query: 220 IPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVT 279
P P + W + + R HL G L I + DQ +++C A N G
Sbjct: 475 GNPPPVIAWTKGGSQLSVDRR-HLVLSS-GT--LRISGVALHDQGQYECQAVNIIGSQKV 530
Query: 280 SCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEEL-KPGD 337
L + PR P F + GA V L C G P+P + W KDG ++ + G
Sbjct: 531 VAHLT-VQPR--VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGK 587
Query: 338 IHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASL 371
H G G G Y C A N +G A+ S L
Sbjct: 588 FHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVL 626
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 67.3 bits (157), Expect = 8e-10
Identities = 68/282 (24%), Positives = 113/282 (40%), Gaps = 26/282 (9%)
Query: 94 NYRKPRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
N +PR Q A +T V F C+ G P P + W ++ EL +L N L
Sbjct: 237 NCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRL---NLLD 293
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEE-KLQLFSKNQAPKFVHGLKSVEAKIDEP 211
+ +N + +++ ++ +E L+ F P FV ++ E + E
Sbjct: 294 DGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGES 353
Query: 212 FRFTIKVAIPPEPSLLWYRDDQ-PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
P P + W R D+ P+ R ++ G++ IQ + D E+ C A
Sbjct: 354 VTLECSATGHPPPRISWTRGDRTPLPVDPRVNI-TPSGGLY---IQNVVQGDSGEYACSA 409
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKD 329
N+ + F+ + P+F Q + EG V+ +C+ G P PV+ W K
Sbjct: 410 TNNIDSVHATAFIIV-----QALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKG 464
Query: 330 GEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
G +L H ++S GT + G Y C+A N +G
Sbjct: 465 GSQLSVDRRHLVLS--SGTLRISGVALHDQGQYECQAVNIIG 504
Score = 54.4 bits (125), Expect = 6e-06
Identities = 51/202 (25%), Positives = 78/202 (38%), Gaps = 31/202 (15%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P+F Q + EG V F+C+ G P PV++W K G +L + + + +L
Sbjct: 428 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGV 487
Query: 152 -----GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
G Y C A N +G A LTV+ P F
Sbjct: 488 ALHDQGQYECQAVNIIGSQKVVAHLTVQP----------------RVTPVFASIPSDTTV 531
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
++ + PEP++ W +D V ES + H+ E FL I + D +
Sbjct: 532 EVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG----FLTINDVGPADAGRY 587
Query: 267 KCVAFNDFGQSVTSCFLKLIIP 288
+CVA N G + S L + +P
Sbjct: 588 ECVARNTIGSASVSMVLSVNVP 609
Score = 50.8 bits (116), Expect = 8e-05
Identities = 69/279 (24%), Positives = 109/279 (39%), Gaps = 27/279 (9%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC-IAKN 160
+N + ++ E V+ EC G P P +SW + + P D ++ T S G Y + +
Sbjct: 344 QNTEVLVGES--VTLECSATGHPPPRISWTRGDRTPLPVDP-RVNITPSGGLYIQNVVQG 400
Query: 161 CMGQASSSAELTVEDIQ-NQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVA 219
G+ + SA ++ + + L F+ + V ++V+ F +
Sbjct: 401 DSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVD--------FQCEAK 452
Query: 220 IPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVT 279
P P + W + + R HL G L I + DQ +++C A N G
Sbjct: 453 GNPPPVIAWTKGGSQLSVDRR-HLVLSS-GT--LRISGVALHDQGQYECQAVNIIGSQKV 508
Query: 280 SCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEEL-KPGD 337
L + PR P F + GA V L C G P+P + W KDG ++ + G
Sbjct: 509 VAHLT-VQPR--VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGK 565
Query: 338 IHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASL 371
H G G G Y C A N +G A+ S L
Sbjct: 566 FHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVL 604
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 67.3 bits (157), Expect = 8e-10
Identities = 68/282 (24%), Positives = 113/282 (40%), Gaps = 26/282 (9%)
Query: 94 NYRKPRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
N +PR Q A +T V F C+ G P P + W ++ EL +L N L
Sbjct: 259 NCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRL---NLLD 315
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEE-KLQLFSKNQAPKFVHGLKSVEAKIDEP 211
+ +N + +++ ++ +E L+ F P FV ++ E + E
Sbjct: 316 DGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGES 375
Query: 212 FRFTIKVAIPPEPSLLWYRDDQ-PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
P P + W R D+ P+ R ++ G++ IQ + D E+ C A
Sbjct: 376 VTLECSATGHPPPRISWTRGDRTPLPVDPRVNI-TPSGGLY---IQNVVQGDSGEYACSA 431
Query: 271 FNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKD 329
N+ + F+ + P+F Q + EG V+ +C+ G P PV+ W K
Sbjct: 432 TNNIDSVHATAFIIV-----QALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKG 486
Query: 330 GEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
G +L H ++S GT + G Y C+A N +G
Sbjct: 487 GSQLSVDRRHLVLS--SGTLRISGVALHDQGQYECQAVNIIG 526
Score = 54.4 bits (125), Expect = 6e-06
Identities = 51/202 (25%), Positives = 78/202 (38%), Gaps = 31/202 (15%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P+F Q + EG V F+C+ G P PV++W K G +L + + + +L
Sbjct: 450 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGV 509
Query: 152 -----GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
G Y C A N +G A LTV+ P F
Sbjct: 510 ALHDQGQYECQAVNIIGSQKVVAHLTVQP----------------RVTPVFASIPSDTTV 553
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
++ + PEP++ W +D V ES + H+ E FL I + D +
Sbjct: 554 EVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG----FLTINDVGPADAGRY 609
Query: 267 KCVAFNDFGQSVTSCFLKLIIP 288
+CVA N G + S L + +P
Sbjct: 610 ECVARNTIGSASVSMVLSVNVP 631
Score = 50.8 bits (116), Expect = 8e-05
Identities = 69/279 (24%), Positives = 109/279 (39%), Gaps = 27/279 (9%)
Query: 102 ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCC-IAKN 160
+N + ++ E V+ EC G P P +SW + + P D ++ T S G Y + +
Sbjct: 366 QNTEVLVGES--VTLECSATGHPPPRISWTRGDRTPLPVDP-RVNITPSGGLYIQNVVQG 422
Query: 161 CMGQASSSAELTVEDIQ-NQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVA 219
G+ + SA ++ + + L F+ + V ++V+ F +
Sbjct: 423 DSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVD--------FQCEAK 474
Query: 220 IPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVT 279
P P + W + + R HL G L I + DQ +++C A N G
Sbjct: 475 GNPPPVIAWTKGGSQLSVDRR-HLVLSS-GT--LRISGVALHDQGQYECQAVNIIGSQKV 530
Query: 280 SCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEEL-KPGD 337
L + PR P F + GA V L C G P+P + W KDG ++ + G
Sbjct: 531 VAHLT-VQPR--VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGK 587
Query: 338 IHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASL 371
H G G G Y C A N +G A+ S L
Sbjct: 588 FHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVL 626
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 67.3 bits (157), Expect = 8e-10
Identities = 75/302 (24%), Positives = 121/302 (40%), Gaps = 53/302 (17%)
Query: 97 KPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F++ +T + F+C+ G P P + W KD EL P Y++ ++L
Sbjct: 261 RPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDHTLKIRK 319
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
GSY C+A+N +G+A +SA LTV++ P FV +
Sbjct: 320 VTAGDMGSYTCVAENMVGKAEASATLTVQE------------------PPHFVVKPRDQV 361
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDD--------QPVDESSRCHLGKEERGVFFLDIQA 257
+ F + P+P++ W R+ QP SSR + + L I
Sbjct: 362 VALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITN 417
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN--LQAILSDEGAVNLECK 315
++ D + C N G +T +L++ + P + + ++ +G L C
Sbjct: 418 VQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCV 477
Query: 316 VIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAAS 367
G P P + W KDG + D RI ++G + G YTC AS G A
Sbjct: 478 ATGSPVPTILWRKDGVLVSTQD-SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATW 536
Query: 368 SA 369
SA
Sbjct: 537 SA 538
Score = 66.5 bits (155), Expect = 1e-09
Identities = 74/296 (25%), Positives = 121/296 (40%), Gaps = 46/296 (15%)
Query: 51 LLFVSLANGWTDLANFGLELFVEVQRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTE 110
L F+ + +G + G+ +V V R + + HN+ V + F +N V+
Sbjct: 127 LFFLRIVHGRKSRPDEGV--YVCVARNYLGEAVSHNASLEVA--ILRDDFRQNPSDVMVA 182
Query: 111 EGLVS-FECKVV-GFPTPVLSWFKDGQELKPGD----------VYQLTGTNSLGSYCCIA 158
G + EC+ G P P +SW KDG L D + T + G Y C+
Sbjct: 183 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVG 242
Query: 159 KNCMGQASSS-AELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
N +G+ S AELTV + P FV ++ +D+ F +
Sbjct: 243 TNMVGERESEVAELTVLE------------------RPSFVKRPSNLAVTVDDSAEFKCE 284
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
P P++ W +DD + +S E R L I+ + D + CVA N G++
Sbjct: 285 ARGDPVPTVRWRKDDGELPKSRY-----EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA 339
Query: 278 VTSCFLKLIIPRHYK-KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
S L + P H+ KPR +++ V +C+ G PQP + W ++G +
Sbjct: 340 EASATLTVQEPPHFVVKPR-----DQVVALGRTVTFQCEATGNPQPAIFWRREGSQ 390
Score = 64.9 bits (151), Expect = 4e-09
Identities = 76/303 (25%), Positives = 127/303 (41%), Gaps = 54/303 (17%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELK-----PGDVYQLTGTNSL 151
PR +E+ ++ +G + CK G PTP + W+K G+ ++ P L + SL
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 127
Query: 152 ---------------GSYCCIAKNCMGQA-SSSAELTVEDIQNQLNEEEKLQLFSKNQAP 195
G Y C+A+N +G+A S +A L V +++ F +N +
Sbjct: 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD---------FRQNPSD 178
Query: 196 KFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDI 255
V + + P PEP++ W +D P+D+ + + L I
Sbjct: 179 VMVAVGEPAVMECQPPRGH-------PEPTISWKKDGSPLDDKDERITIRGGK----LMI 227
Query: 256 QALEFLDQAEWKCVAFNDFGQSVTSCFLKLII--PRHYKKPRFLENLQAILSDEGAVNLE 313
D ++ CV N G+ + ++ P K+P NL A+ D+ A +
Sbjct: 228 TYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP---SNL-AVTVDDSA-EFK 282
Query: 314 CKVIGVPQPVLKWYKDGEELKPG-----DIHRIISGQDGTCSLGTYTCEASNCMGVAASS 368
C+ G P P ++W KD EL D H + + +G+YTC A N +G A +S
Sbjct: 283 CEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEAS 342
Query: 369 ASL 371
A+L
Sbjct: 343 ATL 345
Score = 43.6 bits (98), Expect = 0.011
Identities = 51/192 (26%), Positives = 79/192 (41%), Gaps = 17/192 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD---ESSRCHLGKEERG-V 250
P+ V + EP K P P++ WY+ + V+ + R H G +
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 127
Query: 251 FFLDIQ--ALEFLDQAEWKCVAFNDFGQSVT-SCFLKLIIPRHYKKPRFLENLQAILSDE 307
FFL I D+ + CVA N G++V+ + L++ I R + + + A+ E
Sbjct: 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV--GE 185
Query: 308 GAVNLECKVI-GVPQPVLKWYKDGEELKPGDIHRIISG------QDGTCSLGTYTCEASN 360
AV +EC+ G P+P + W KDG L D I G G Y C +N
Sbjct: 186 PAV-MECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTN 244
Query: 361 CMGVAASSASLL 372
+G S + L
Sbjct: 245 MVGERESEVAEL 256
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 65.7 bits (153), Expect = 2e-09
Identities = 212/1174 (18%), Positives = 503/1174 (42%), Gaps = 107/1174 (9%)
Query: 1926 ILQESLGETKQKIECDTNDEALD--IKAALMEMVEPLQNLHTQLIHVQEVVLSGVQEDSI 1983
+L+E+ ++ + + D + A E+ Q L + VQE + + + +
Sbjct: 836 VLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLN---EMEQL 892
Query: 1984 SLDIDSAESIVQTISDVHKKISAKLELETVNVSDKDVALIFEVDKDLHAIQDSIKALKNQ 2043
+++ +S +QT+ I+ KL+ +T+ ++V + + DL +Q+S++ ++Q
Sbjct: 893 KEQLENRDSPLQTVEREKTLITEKLQ-QTL----EEVKTLTQEKDDLKQLQESLQIERDQ 947
Query: 2044 PAAQDIKDVTKQIQDVEKSLHVLVASENVITDVKDKIPKGSTEQLVQHINQYXXXXXXXX 2103
DI D D ++ L + S + + + +E++ ++++
Sbjct: 948 -LKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKD 1006
Query: 2104 XXXXXXXXXDLKETIEMAKDLRETFVTSDMINDEVAESIKEEI-LIEQARLAHKLQKAIS 2162
D K+ +E AK+ + +T+D+ ++E+ E ++ LI++ ++ +++
Sbjct: 1007 EFQQKMVGIDKKQDLE-AKNTQT--LTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVI 1063
Query: 2163 ALQVQVFDSAQEMVPELSTEIFQRVARVTAQL--QADLMAVTGVHITIQAPPY--VLDEV 2218
A + Q+ +E + E++ E + + + +L Q +++A H + D +
Sbjct: 1064 AEKEQLKTDLKENI-EMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRL 1122
Query: 2219 AKSLETISTENRLVPESAQGDKLVSIVENVNMFENTADPPIQPKPKELSN--ITVEPEEV 2276
A+ E + +++ + E Q +L+++ E ++ + + I+ EL N +T+E E
Sbjct: 1123 AEVEEKLKEKSQQLQEKQQ--QLLNVQEEMSEMQKKINE-IENLKNELKNKELTLEHMET 1179
Query: 2277 NITQLLEDVSSNERVINENLVTVTQEVAVAQ-----METNMD-IAGVTKKTQ-DGL-IKD 2328
+L + ++ N E + ++T+E V + ET D + G ++ + GL K+
Sbjct: 1180 ERLELAQKLNENY----EEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE 1235
Query: 2329 DIK--SFSISEEAQSIFE---QGSPEVYNVLNAEELASNQTFSADSASNNMPDNELDIVE 2383
++K + E ++I E S + ++N ++L + T + + E +++
Sbjct: 1236 ELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIP--VLHEEQELLP 1293
Query: 2384 PVLVCSVPASSLDDLEGSVNPKT--GLVTDEKIDLQKVDVTIEMPE----IAQLDKCQPF 2437
V S ++++LE T T +I+++++ + + E I L K +
Sbjct: 1294 NVKKVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDN 1353
Query: 2438 YANLHELM-----QSVDLAKQLQKSITISESVIEPNIETEPNPQSPVYLAS---QLKMAL 2489
+ E + Q + ++ I S+S E ++ + + S Q K
Sbjct: 1354 LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKD 1413
Query: 2490 LVLYNQDIESLEVMAP-HLTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESV 2548
L +IE L + + D++K +++ DDL ++ E +QS + + ++KE
Sbjct: 1414 SALLRIEIEMLGLSKRLQESHDEMKSVAKEK----DDLQRLQEVLQSESDQLKENIKE-- 1467
Query: 2549 QKANVVEQDLNSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIK 2608
+V + L + EE+ ++ QE + V K +++
Sbjct: 1468 ----IVAKHLETEEEL-KVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQ 1522
Query: 2609 SVVGKITDNLFSIEAAQSIEVKEDFSDVK--STDLRVTDSVTEVLESSDVRVIENVSKSD 2666
+ + +I + + Q EV+E+ +++K + DS + +ES +++E ++
Sbjct: 1523 NKIQEIYEKEEQLNIKQISEVQENVNELKQFKEHRKAKDSALQSIES---KMLELTNRLQ 1579
Query: 2667 DVPTNINLLVDDSLLEIDKAVKSTEALKNIPQRDLAENEQQLGEDTTGSKQKVVE-LPDT 2725
+ I +++ E ++ + EAL+ I + L EN +++ S++K + L T
Sbjct: 1580 ESQEEIQIMIK----EKEEMKRVQEALQ-IERDQLKENTKEIVAKMKESQEKEYQFLKMT 1634
Query: 2726 IDDVSQDMI--VEHLPTS-EVKLLEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSV 2782
+ +Q+ + +EHL E + L + + E L++ L +L ++ T+ D SV
Sbjct: 1635 AVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSV 1694
Query: 2783 DLVKIAGEPEIKSKLVEELQTIADSKSQKMIEESTTRETVESPLITTGKTTETPNDITSM 2842
+ ++K L E + + + + I +E E+ G +E N+I++M
Sbjct: 1695 EETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNM 1754
Query: 2843 NVGETEKQRKESITELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDL 2902
+K+ + S+D K+Q + + +E+ + H+ +K +E +
Sbjct: 1755 --------QKDL-----EHSNDALKAQDL--KIQEELRIAHM---HLKEQQETIDKLRGI 1796
Query: 2903 TAEVNLPLVTGHETIQTLNSNLENEMCESLKIEQAVSAETTESTVESQRVASEVILELVS 2962
+E L + ++ N+ L+ E + LK + + E+Q+ SE +E +
Sbjct: 1797 VSEKTDKLSNMQKDLENSNAKLQ-EKIQELKANEHQLITLKKDVNETQKKVSE--MEQLK 1853
Query: 2963 EQLKKDQAESSNSQTAENIVREIVVTSEITALETLGLPLERSGNDGDLVELLSIETKQIT 3022
+Q+ KDQ+ + + EN+ + + ++++ + + ++L + K+
Sbjct: 1854 KQI-KDQSLTLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRVEETLKLERDQLKESL 1912
Query: 3023 VEPRATTYEVVAEQQVVPS-GQQPVEAIDSMKKE 3055
E +A E+ E + ++ E +D ++++
Sbjct: 1913 QETKARDLEIQQELKTARMLSKEHKETVDKLREK 1946
Score = 56.0 bits (129), Expect = 2e-06
Identities = 235/1229 (19%), Positives = 506/1229 (41%), Gaps = 135/1229 (10%)
Query: 1782 LATVRQSLIKIVESQSELLFKSPIVNLKYLSHRNHFDKMANLVAKLD-DFVDAVKPNAEN 1840
L ++R +V +L + + LK L +N D+ L K D + N
Sbjct: 500 LNSLRADYDNLVLDYEQLRTEKEEMELK-LKEKNDLDEFEALERKTKKDQEMQLIHEISN 558
Query: 1841 IKDKII-MELKNLDLCNVNNEENKLVRTMDDFFRFVEDEIVVQEDNDKKVILKKILTCLE 1899
+K+ + E+ N DL N + + +L+R +D + +++ I Q+ + K+ L L +E
Sbjct: 559 LKNLVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIE 618
Query: 1900 KDRDYKDAT-DAGKVLIIMHCLSNCVDILQESLGETKQKIECDTNDEALDIKAALMEMVE 1958
+ K DA V + D +ES + +E ++ ++ +M
Sbjct: 619 DPKQMKQTLFDAETVAL---------DAKRESAFLRSENLEL--KEKMKELATTYKQMEN 667
Query: 1959 PLQNLHTQLIHVQEVVLSGVQE-DSISLDIDSAESIVQTISDVHKKISAKLELETVNVSD 2017
+Q +QL +++ + +E S +I S++ V K + LELE ++D
Sbjct: 668 DIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLID--GKVPKDLLCNLELEG-KITD 724
Query: 2018 KDVALIFEVDKDLHAIQDSIKALKNQPAAQDIKDVTKQIQDVEKSLHVLVA-SENVITDV 2076
L EV+++ ++ I + + +++ + K+IQD + LH++ + + + ++V
Sbjct: 725 LQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEV 784
Query: 2077 KDKIPKGSTEQLVQHINQYXXXXXXXXXXXXXXXXXDLKETIEMAKDLRETFVTSDMIND 2136
K + + L++ I + + + K L F +
Sbjct: 785 VHK--ESRVQGLLEEIGK-----TKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVL 837
Query: 2137 EVAESIKEEILIEQARLAHKLQKAISALQVQVFDSAQEMVPELSTEIFQRVARVTAQLQA 2196
E E + +EI + ++ A K ++ AL+ ++ QE+ E + E+ +R+ + QL+
Sbjct: 838 EENERMNQEI-VNLSKEAQKFDSSLGALKTELSYKTQEL-QEKTREVQERLNEM-EQLKE 894
Query: 2197 DLMAVTGVHITIQAPPYVLDEVAKSLETISTENRLVPESAQGDKLVSIVENVNMFENTAD 2256
L T++ ++ E K +T+ L E D L + E++ + +
Sbjct: 895 QLENRDSPLQTVEREKTLITE--KLQQTLEEVKTLTQEK---DDLKQLQESLQIERDQLK 949
Query: 2257 PPIQPKPKELSNITVEPEEVNITQLLEDVSSNERVINENLVTVTQEVAVAQMETNMDIAG 2316
I + N+ ++ +E + LE + ++ IN +++EV+ N+ +
Sbjct: 950 SDIH----DTVNMNIDTQE-QLRNALESLKQHQETINTLKSKISEEVS-----RNLHMEE 999
Query: 2317 VTKKTQDGLIKDDIKSFSISEEAQSIFEQGSPEVYNVLNAEELASNQTFSADSASNNMPD 2376
T +T+D + K I ++ Q + E + QT +AD N + +
Sbjct: 1000 NTGETKDEFQQ---KMVGI-DKKQDL---------------EAKNTQTLTADVKDNEIIE 1040
Query: 2377 NELDIVEPVLVCSVPASSLDDLEGSVNPKTGLVTDEKIDLQKVDVTIEMPEIA-----QL 2431
+ I + LE + K L TD K + +++TIE E +L
Sbjct: 1041 QQRKIFS---LIQEKNELQQMLESVIAEKEQLKTDLK---ENIEMTIENQEELRLLGDEL 1094
Query: 2432 DKCQPFYA--NLHELMQSVDLAKQLQKSITISESVIEPNIETEPNPQSPVYLASQLKMAL 2489
K Q A H + + +L++ + + E + E + + + Q L Q +M+
Sbjct: 1095 KKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQ--LLNVQEEMSE 1152
Query: 2490 LVLYNQDIESL--EVMAPHLTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKES 2547
+ +IE+L E+ LT + ++ +E + L L + E V+S T E V +
Sbjct: 1153 MQKKINEIENLKNELKNKELTLEHME--TERL-ELAQKLNENYEEVKS--ITKERKVLKE 1207
Query: 2548 VQKANVVEQDLNSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEI 2607
+QK+ E+D + I EI T +E +I ETID E+
Sbjct: 1208 LQKSFETERD-HLRGYIREIEATGLQTKEELKIAHI----------HLKEHQETID--EL 1254
Query: 2608 KSVVGKITDNLFSIEAAQSIEVKEDFSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDD 2667
+ V + T + + + + K ++ V E+L + ++ VS++ +
Sbjct: 1255 RRSVSEKTAQIINTQDLEKSHTK------LQEEIPVLHEEQELLPN-----VKKVSETQE 1303
Query: 2668 VPTNINLLVDDSLLEIDKAVKSTEALKNIPQRDLAENEQQLGEDTTGSKQKVVELPDTID 2727
+ LL + S + D + ++ + + + Q+ + T + + + + +
Sbjct: 1304 TMNELELLTEQSTTK-DSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEAL- 1361
Query: 2728 DVSQDMIVEHLPTSEVKLLEGQLLAAEENTLSEALKSSLVTVQKTTE-TPLDDTSVDL-V 2785
+V D + EH+ + K+ E Q + + E + V + + P D + + +
Sbjct: 1362 EVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEI 1421
Query: 2786 KIAGEPEIKSKLVEELQTIADSKS--QKMIE--ESTTRETVESPLITTGKTTETPNDITS 2841
++ G + + +E++++A K Q++ E +S + + E+ K ET ++
Sbjct: 1422 EMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKV 1481
Query: 2842 MNVGETEKQRKESITELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKED 2901
+ K+++E+I EL S+ ++ +S + +++ I+D+++ ++ KE+
Sbjct: 1482 AHC--CLKEQEETINELRVNLSE---KETEISTIQKQL---EAINDKLQNKIQEIYEKEE 1533
Query: 2902 LTAEVNLPLVTG-HETIQTLNSNLENEMCESLKIEQAVSAETTESTVESQRVASEV-ILE 2959
++N+ ++ E + L E+ + + Q++ ++ E T Q E+ I+
Sbjct: 1534 ---QLNIKQISEVQENVNELKQFKEHRKAKDSAL-QSIESKMLELTNRLQESQEEIQIMI 1589
Query: 2960 LVSEQLKKDQ--AESSNSQTAENIVREIV 2986
E++K+ Q + Q EN +EIV
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKEN-TKEIV 1617
Score = 54.0 bits (124), Expect = 8e-06
Identities = 218/1208 (18%), Positives = 502/1208 (41%), Gaps = 120/1208 (9%)
Query: 1719 NEFTILRCLLNKSMSPKKIIRLVQEFCN--IQSTIQGFKTKTNELQLSDDVNQCIESFLI 1776
NE L+ L SP + + + +Q T++ KT T E DD+ Q ES I
Sbjct: 887 NEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQE---KDDLKQLQESLQI 943
Query: 1777 HSDDCLATVRQSLIKIVESQSELLFKSPIVNLKYLSHRNHFDKMANLVAKLDDFVDA--- 1833
D + + ++ +++Q +L ++ + +LK H + + L +K+ + V
Sbjct: 944 ERDQLKSDIHDTVNMNIDTQEQL--RNALESLK-----QHQETINTLKSKISEEVSRNLH 996
Query: 1834 VKPNAENIKD----KII-------MELKNLDLCNVNNEENKLVRTMDDFFRFVEDEIVVQ 1882
++ N KD K++ +E KN + ++N+++ F ++++ +Q
Sbjct: 997 MEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ 1056
Query: 1883 EDNDKKVILKKILTCLEKDRDYKDATDAGKVLIIMHCLSNCVDIL-QESLGETKQKIECD 1941
+ + + K+ L K+ + ++ ++ L +I+ QE K++ E
Sbjct: 1057 QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELS 1116
Query: 1942 -TNDEALDIKAALMEMVEPLQNLHTQLIHVQEVVLSGVQEDSISLDIDSAESIVQTISDV 2000
T D +++ L E + LQ QL++VQE +S +Q+ ++ E + ++
Sbjct: 1117 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQE-EMSEMQKKINEIENLKNELKNKELTLE 1175
Query: 2001 HKKISAKLEL-ETVNVSDKDVALIFEVDKDLHAIQDSIKALKN--QPAAQDIKDVTKQIQ 2057
H + + +LEL + +N + ++V I + K L +Q S + ++ + ++I+ Q +
Sbjct: 1176 HME-TERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTK 1234
Query: 2058 DVEKSLHVLVASENVITDVKDKIPKGSTEQLVQHINQYXXXXXXXXXXXXXXXXXDLKET 2117
+ K H+ + + D++ + +E+ Q IN L E
Sbjct: 1235 EELKIAHIHLKEHQ---ETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPV---LHEE 1288
Query: 2118 IEMAKDLRETFVTSDMINDEVAESIKEEILIEQARLAHKLQKAISALQVQVFDSAQEMVP 2177
E+ ++++ T + +N+ E + E+ + + +++ L + F +QE +
Sbjct: 1289 QELLPNVKKVSETQETMNE--LELLTEQSTTKDSTTLARIEMERLRLN-EKFQESQEEIK 1345
Query: 2178 ELSTEIFQRVARVTAQLQADLMAVTGVHITIQAPPYVLDEVAKSLETISTENRLVPESAQ 2237
L+ E L+ A+ H Q ++ + +AK E+ S + + + +
Sbjct: 1346 SLTKE--------RDNLKTIKEALEVKH--DQLKEHIRETLAKIQESQSKQEQSLNMKEK 1395
Query: 2238 GDKLVSIVENVNMFENTADPPIQPKPKELSNITVEPEEVNITQLLEDVSSNERVINENLV 2297
++ IV + F KPK+ + + +E E + +++ L++ + + +
Sbjct: 1396 DNETTKIVSEMEQF----------KPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKD 1445
Query: 2298 TVTQEVAVAQMETNM---DIAGVTKKTQDGLIKDDIKSFSISEEAQSIFEQGSPEVYNVL 2354
+ + V Q E++ +I + K + + + + E+ ++I E N+
Sbjct: 1446 DLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELR----VNLS 1501
Query: 2355 NAEELASNQTFSADSASNNMPDNELDIVEPVLVCSVPASSLDDLEGSVNPKTGLVTDEKI 2414
E S ++ ++ + + +I E ++ + +++ +VN K
Sbjct: 1502 EKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNI--KQISEVQENVNELKQFKEHRKA 1559
Query: 2415 DLQKVDVTIEMPEIAQLDKCQPFYANLHELMQSVDLAKQLQKSITISESVIEPNIE--TE 2472
+ +IE + ++ Q + +++ + K++Q+++ I ++ N +
Sbjct: 1560 KDSALQ-SIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVA 1618
Query: 2473 PNPQSPVYLASQLKMALLVLYNQDIESLEVMAPHLTKDKLKVISEIVHNLCDDLTQVMEA 2532
+S LKM + + + +E + KL + + N+ LTQ++
Sbjct: 1619 KMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENI--RLTQIL-- 1674
Query: 2533 VQSNQNTSESSVKESVQKANVVEQDLNSPEEIDEI--FETKTPLQEVGTAQNIVXXXXXX 2590
N S KE DL S EE ++ + K L+E T
Sbjct: 1675 -HENLEEMRSVTKE--------RDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKI 1725
Query: 2591 XXXXXXXKHETIDTAEIKSVVGKITDNLFSIEAAQSIEVKEDFSDVKSTDLRVTDSVTEV 2650
ETID +++ +V + T+ + +++ + +E D +K+ DL+ + E
Sbjct: 1726 VHMHLKEHQETID--KLRGIVSEKTNEISNMQ--KDLEHSND--ALKAQDLK----IQEE 1775
Query: 2651 LESSDVRVIENVSKSDDVPTNINLLVDDSLLEIDKAVKSTEALKNIPQRDLAENEQQ--- 2707
L + + + E D + I D L + K ++++ A ++L NE Q
Sbjct: 1776 LRIAHMHLKEQQETIDKL-RGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLIT 1834
Query: 2708 LGEDTTGSKQKVVELPDTIDDVSQDMIVEHLPTSEVKLLEGQLLAAEENTLSEALKSSLV 2767
L +D +++KV E+ + + + + + L S+++ +E LA E + E +KS V
Sbjct: 1835 LKKDVNETQKKVSEM----EQLKKQIKDQSLTLSKLE-IENLNLAQELHENLEEMKS--V 1887
Query: 2768 TVQKTTETPLDDTSVDLVKIAGEPEIKSKLVEELQTIADSKSQKMIEESTTRETVESPLI 2827
++ +++T + L + + ++ +L+ + K+ +M+ + +ETV+
Sbjct: 1888 MKERDNLRRVEET-LKLERDQLKESLQETKARDLEIQQELKTARMLSKE-HKETVD---- 1941
Query: 2828 TTGKTTETPNDITSMNVGETEKQRKESITELNQKSSDFTKSQSIVSDVSQEILVEHLISD 2887
K E ++ T + + + +K +S EL +K + K + + V +++ + H +
Sbjct: 1942 ---KLREKISEKT-IQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKIN 1997
Query: 2888 EIKFTKEQ 2895
E++ K+Q
Sbjct: 1998 EMEQLKKQ 2005
Score = 49.6 bits (113), Expect = 2e-04
Identities = 205/1066 (19%), Positives = 435/1066 (40%), Gaps = 91/1066 (8%)
Query: 745 EIISSLINPLSEILSITDTIQESASETIEVQRTLFSRLPKPLKVLQQTLTIIEKCIDVES 804
E+ L + ++E + ++E+ TIE Q L L LK QQ + EK ++
Sbjct: 1054 ELQQMLESVIAEKEQLKTDLKENIEMTIENQEEL-RLLGDELKK-QQEIVAQEKNHAIKK 1111
Query: 805 DNRTLVKKTC---VSIMEKCGNAIQNLVS-EINAIEKKEYLLLSENVCNELDVVSNEIS- 859
+ + +TC + EK Q L + + +E + + NE++ + NE+
Sbjct: 1112 EGE--LSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKN 1169
Query: 860 ---TVVNFSTESIKTNNLLNETTEVKLESTVESKHLTDTQKALFELKGPLRSLLYIVDSA 916
T+ + TE ++ LNE E T E K L + QK+ + LR YI +
Sbjct: 1170 KELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRG--YIREIE 1227
Query: 917 ESGKIVDISQVNNSEVILNDMSASIQDLQSALEQIESLSVLECATSLNKYNTEIIENVME 976
+G + ++ + + L + +I +L+ ++ E + + L K +T++ E +
Sbjct: 1228 ATG-LQTKEELKIAHIHLKEHQETIDELRRSVS--EKTAQIINTQDLEKSHTKLQEEI-- 1282
Query: 977 PVLQLRSSFEKMSTEIKAEDKIQLNKVLSSIKENLTVISSYINKVENNIGAFDVLQNENK 1036
PVL ++ +E + +N++ +++ T S+ + ++E + L+ K
Sbjct: 1283 PVLHEEQELLPNVKKV-SETQETMNELELLTEQSTTKDSTTLARIE-----MERLRLNEK 1336
Query: 1037 LEALQKMAETLISLEKNLPTLDTMPQVQGNMNSFHKNLTKALEKVIESNNANKYLSMIEI 1096
+ Q+ ++L NL T+ +V+ + H + + L K+ ES +K + +
Sbjct: 1337 FQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEH--IRETLAKIQESQ--SKQEQSLNM 1392
Query: 1097 CDGIRRINSCIRDMDTDNILSLASLSNTLKIIQNQFIKNIFDSELNCCVVTNITDILIGI 1156
+ + +M+ A L ++++ K + +S V D L +
Sbjct: 1393 KEKDNETTKIVSEMEQFKPKDSALLRIEIEML--GLSKRLQESHDEMKSVAKEKDDLQRL 1450
Query: 1157 QETINQAQEFTTEIQYDNFQDTQAPIFDSTKVEIIVEH--VNQTVAAINQVKLLETTSSL 1214
QE + + E N ++ A + T+ E+ V H + + IN+ L S
Sbjct: 1451 QEVLQSESDQLKE----NIKEIVAKHLE-TEEELKVAHCCLKEQEETINE---LRVNLSE 1502
Query: 1215 KENITPTLQKICPILEELKQNIASACVGGIQKEAYVSDISE--KSFSE--KFAVPLSELN 1270
KE T+QK + + QN + +++ + ISE ++ +E +F +
Sbjct: 1503 KETEISTIQKQLEAINDKLQNKIQE-IYEKEEQLNIKQISEVQENVNELKQFKEHRKAKD 1561
Query: 1271 HNVIVLNQTIIENIESLKESNEIVTAIAEPLQELFRTLEVIQQDVISQFGPDLSPYEISV 1330
+ + ++E L+ES E + + + +E+ R E +Q I + + EI
Sbjct: 1562 SALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQ---IERDQLKENTKEI-- 1616
Query: 1331 DIASIIQSLQSCVVMIQDHAAIEVVDDMSTLEDISGIKTTAETASADQLVLPTAEFATTE 1390
+A + +S + ++ A E + M +E +K ET + + T T+
Sbjct: 1617 -VAKMKESQEKEYQFLKMTAVNETQEKMCEIEH---LKEQFETQKLNLENIETENIRLTQ 1672
Query: 1391 QTLGSFYDEQPKSSIAQALHVLNEHLTILQSPEIIDAIDTLS-EISDYSSLKSVTLGLSD 1449
+ + + + L + E L + + + +T++ ++ LK V + L +
Sbjct: 1673 ILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKE 1732
Query: 1450 LHSGIEEVLQPIVLEGLQSINASKLAAMAEPMQVLQHSLSVVDPNNIPIYENILELLTDN 1509
I++ L G+ S ++++ M + L+HS + ++ I E EL +
Sbjct: 1733 HQETIDK------LRGIVSEKTNEISNMQKD---LEHSNDALKAQDLKIQE---ELRIAH 1780
Query: 1510 IHSVLNKINAFKEHLDKCMQAILPALE-FTKQSIEISSSVNKLREACQHLKI---MLKSI 1565
+H + +E +DK + + + ++ +S KL+E Q LK L ++
Sbjct: 1781 MH-----LKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITL 1835
Query: 1566 NQSSTTQIPEVQVLDDVVNEILIATDVTEGIKIEQVRYLSEELYARVAGVREEILRFTPN 1625
+ +V ++ + +I + ++IE + L++EL+ + EE+
Sbjct: 1836 KKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLN-LAQELHENL----EEMKSVMKE 1890
Query: 1626 SSEALPNEASFIHTIEEVEHNIAVLEEYDFVDLSRASELSSCASPQIAKEVEIESLVHIS 1685
E + ++++ + L+E DL EL + + ++KE + E++ +
Sbjct: 1891 RDNLRRVEETLKLERDQLKES---LQETKARDLEIQQELKT--ARMLSKEHK-ETVDKLR 1944
Query: 1686 EIVETAVRIIKDAGEDTPMADLMIVEDFFTTCKNEFTILRCLLNKSMSPKKIIRLVQEFC 1745
E + I D +D + + + K E +LR + +MS KKI + Q
Sbjct: 1945 EKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKK 2004
Query: 1746 NIQSTIQGFKTKTNELQLSDDVNQCIESFLI--HSDDCLATVRQSL 1789
+ K + + QL+ +++ +E I D L +++SL
Sbjct: 2005 QFEPNYL-CKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESL 2049
Score = 46.4 bits (105), Expect = 0.002
Identities = 225/1185 (18%), Positives = 471/1185 (39%), Gaps = 113/1185 (9%)
Query: 861 VVNFSTESIKTNNLLNETTEVKLESTVESKHLTDTQKALFELKGPLRSLLYIVDSAESGK 920
+VN S E+ K ++ L +K E + +++ L + + + E + L +++ +S
Sbjct: 847 IVNLSKEAQKFDSSLGA---LKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDS-- 901
Query: 921 IVDISQVNNSEVILNDMSASIQDLQSALEQIESLSVLECATSLNKYNTEIIENVMEPVLQ 980
+ V + ++ + LQ LE++++L T ++ E++ Q
Sbjct: 902 --PLQTVEREKTLITEK------LQQTLEEVKTL------TQEKDDLKQLQESLQIERDQ 947
Query: 981 LRSSFEKMSTEIKAEDKIQLNKVLSSIKENLTVISSYINKVENNIGAFDVLQNENKLEAL 1040
L+S + + + + QL L S+K++ I++ +K+ + ++ EN E
Sbjct: 948 LKSDIHD-TVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSR-NLHMEENTGETK 1005
Query: 1041 QKMAETLISLEK--NLPTLDTMPQVQG-NMNSFHKNLTKALEKVIESNNANKYL-SMIEI 1096
+ + ++ ++K +L +T N + K + E N + L S+I
Sbjct: 1006 DEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAE 1065
Query: 1097 CDGIRRINSCIRDMDTDNILSLASLSNTLKIIQ-------NQFIKNIFDSELNCCVVTNI 1149
+ ++ +M +N L L + LK Q N IK + C + +
Sbjct: 1066 KEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEV 1125
Query: 1150 TDILIGIQETINQAQEFTTEIQYDNFQDTQAPIFDSTKVEIIVEHVNQTVAAINQVKLLE 1209
+ L + + + Q+ +Q + + Q I + ++ +++ T+ + + + LE
Sbjct: 1126 EEKLKEKSQQLQEKQQQLLNVQ-EEMSEMQKKINEIENLKNELKNKELTLEHM-ETERLE 1183
Query: 1210 TTSSLKENI--TPTLQKICPILEELKQNIASAC--VGGIQKEAYVSDISEKSFSEKFAVP 1265
L EN ++ K +L+EL+++ + + G +E + + K + +
Sbjct: 1184 LAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIH 1243
Query: 1266 LSELNHNVIVLNQTIIENIESLKESNEIV---TAIAEPLQELFRTLEVIQQ-DVISQFGP 1321
L E + L +++ E + + ++ T + E + L E++ +S+
Sbjct: 1244 LKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQE 1303
Query: 1322 DLSPYEISVDIASIIQSLQSCVVMIQ----DHAAIEVVDDMSTL-EDISGIKTTAETASA 1376
++ E+ + ++ S + ++ + E +++ +L ++ +KT E
Sbjct: 1304 TMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEV 1363
Query: 1377 --DQLVLPTAEF--------ATTEQTLGSFYDEQPKSSIAQALHVLNEHLTILQSPEIID 1426
DQL E + EQ+L + + I + + L EI +
Sbjct: 1364 KHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEI-E 1422
Query: 1427 AIDTLSEISD-YSSLKSVTLGLSDLHSGIEEVLQPI---VLEGLQSINASKLAAMAEPMQ 1482
+ + + + +KSV DL ++EVLQ + E ++ I A L E ++
Sbjct: 1423 MLGLSKRLQESHDEMKSVAKEKDDLQR-LQEVLQSESDQLKENIKEIVAKHLET-EEELK 1480
Query: 1483 VLQHSLSVVDPNNIPIYENILELLTDNIHSVLNKINAFKEHLDKCMQAILPALEFT--KQ 1540
V L + + N+ E T+ I ++ ++ A + L +Q I E KQ
Sbjct: 1481 VAHCCLKEQEETINELRVNLSEKETE-ISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQ 1539
Query: 1541 SIEISSSVNKLREACQHLKI---MLKSINQSS---TTQIPEVQ-VLDDVVNEILIATDVT 1593
E+ +VN+L++ +H K L+SI T ++ E Q + ++ E V
Sbjct: 1540 ISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQ 1599
Query: 1594 EGIKIE--QVRYLSEELYARVAGVREEILRFTPNS--SEALPNEASFIHTIEEVEHNIAV 1649
E ++IE Q++ ++E+ A++ +E+ +F + +E H E+ E
Sbjct: 1600 EALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLN 1659
Query: 1650 LEEYDFVDLSRASELSSCASPQIAKEVEIESLVHISEIVETAVRIIKDAGEDTPMADLMI 1709
LE + ++ L + E + L + E ++ +K+ +T DL
Sbjct: 1660 LENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEK 1719
Query: 1710 VEDFFTTCKNEFTILRCLLNKSMSP-KKIIRLVQEFCNIQSTIQGFKTKTNELQLSDDVN 1768
E E I+ L + K+ +V E N S +Q +N+ + D+
Sbjct: 1720 QE--------ELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLK 1771
Query: 1769 QCIESFLIHS---------DDCLATVRQSLIKIVESQSELLFKSPIVNLKYLSHRNHFDK 1819
E + H D V + K+ Q +L + + K + + +
Sbjct: 1772 IQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQ 1831
Query: 1820 MANL---VAKLDDFVDAVKPNAENIKDKII----MELKNLDLC---NVNNEENKLVRTMD 1869
+ L V + V ++ + IKD+ + +E++NL+L + N EE K V
Sbjct: 1832 LITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKER 1891
Query: 1870 DFFRFVEDEIVVQEDNDKKVILKKILTCLEKDRDYKDATDAGKVLIIMHCLSNCVDILQE 1929
D R VE+ + ++ D K+ + + LE ++ K A ++L H VD L+E
Sbjct: 1892 DNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTA----RMLSKEH--KETVDKLRE 1945
Query: 1930 SLGETKQKIECDTNDEALDIKAALMEMVEPLQNLHTQLIHVQEVV 1974
+ E +I D + K L + ++ LQ QL+ V+E V
Sbjct: 1946 KISEKTIQIS-DIQKDLDKSKDELQKKIQELQKKELQLLRVKEDV 1989
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 64.9 bits (151), Expect = 4e-09
Identities = 74/288 (25%), Positives = 118/288 (40%), Gaps = 45/288 (15%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTNSL-------- 151
+E + A++ E + +F C V +P P +SW ++ +K D Y + L
Sbjct: 34 LETVDALVEE--VATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVED 91
Query: 152 ---GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G YCC A N +G A S L + K ++ K + GLK+V
Sbjct: 92 SDDGIYCCTANNGVGGAVESC--------GALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
P+PS+ W + D P+ E+SR + E G L I ++ D +++C
Sbjct: 140 -----LPCTTMGNPKPSVSWIKGDSPLRENSR--IAVLESGS--LRIHNVQKEDAGQYRC 190
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK 328
VA N G + + +KL + + R E+ V L C G+P P + W +
Sbjct: 191 VAKNSLGTAYSKV-VKLEVEVFARILRAPESHNVTFGS--FVTLHCTATGIPVPTITWIE 247
Query: 329 DGEELKPGDIHRIISGQ--DGTCSL-----GTYTCEASNCMGVAASSA 369
+G + G I + + D L G YTC A+N G S+A
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTA 295
Score = 47.2 bits (107), Expect = 0.001
Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 25/188 (13%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP L++V+A ++E F V P+P + W R ++ + + E G
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTR-NKILIKLFDTRYSIRENGQ-L 83
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSC-----FLKLIIPRHYKKPRFLENLQAILSDE 307
L I ++E D + C A N G +V SC +K I R + +E L+A+
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 308 GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEAS 359
L C +G P+P + W K L+ RI + G+ + G Y C A
Sbjct: 140 ----LPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGSLRIHNVQKEDAGQYRCVAK 193
Query: 360 NCMGVAAS 367
N +G A S
Sbjct: 194 NSLGTAYS 201
>BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 64.9 bits (151), Expect = 4e-09
Identities = 44/173 (25%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ +N+++ +Q K P+F+ +++ R KV+ P P + WY + + V
Sbjct: 234 RGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ 291
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
+ E+G+ L + + D + CVA N G++ + L ++ H + P F
Sbjct: 292 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 351
Query: 297 LENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGT 348
+ Q+ EG +V LEC++ +P P L W K E+ + RI QD T
Sbjct: 352 IYKPQSKKVLEGDSVKLECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNT 403
Score = 62.9 bits (146), Expect = 2e-08
Identities = 54/216 (25%), Positives = 103/216 (47%), Gaps = 31/216 (14%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
N + + + PRF++ + + +EG + KV G P P +SW+ +G+ ++ D+++
Sbjct: 238 NDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHK 297
Query: 145 LT----GTNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFS 190
+ G +SL G+Y C+AKN G+A+ + +L V L +E K
Sbjct: 298 MIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV------LAKEHK----- 346
Query: 191 KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERG 249
+AP F++ +S + + + +++ P P L W R+++ V + R L ++ G
Sbjct: 347 --RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTG 404
Query: 250 VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
L I+ + D + A N+ G VT+C +L
Sbjct: 405 RVTLLIKDVNKKDAGWYTVSAVNEAG--VTTCNTRL 438
Score = 47.6 bits (108), Expect = 7e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
Query: 287 IPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ 345
I + PRF++ + + DEG ++ KV G+P P + WY +G ++ D+H++I +
Sbjct: 243 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 302
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASL 371
G SL G Y C A N G A + L
Sbjct: 303 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL 338
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 64.9 bits (151), Expect = 4e-09
Identities = 74/288 (25%), Positives = 118/288 (40%), Gaps = 45/288 (15%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTNSL-------- 151
+E + A++ E + +F C V +P P +SW ++ +K D Y + L
Sbjct: 34 LETVDALVEE--VATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVED 91
Query: 152 ---GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G YCC A N +G A S L + K ++ K + GLK+V
Sbjct: 92 SDDGIYCCTANNGVGGAVESC--------GALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
P+PS+ W + D P+ E+SR + E G L I ++ D +++C
Sbjct: 140 -----LPCTTMGNPKPSVSWIKGDSPLRENSR--IAVLESGS--LRIHNVQKEDAGQYRC 190
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK 328
VA N G + + +KL + + R E+ V L C G+P P + W +
Sbjct: 191 VAKNSLGTAYSKV-VKLEVEVFARILRAPESHNVTFGS--FVTLHCTATGIPVPTITWIE 247
Query: 329 DGEELKPGDIHRIISGQ--DGTCSL-----GTYTCEASNCMGVAASSA 369
+G + G I + + D L G YTC A+N G S+A
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTA 295
Score = 47.2 bits (107), Expect = 0.001
Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 25/188 (13%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP L++V+A ++E F V P+P + W R ++ + + E G
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTR-NKILIKLFDTRYSIRENGQ-L 83
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSC-----FLKLIIPRHYKKPRFLENLQAILSDE 307
L I ++E D + C A N G +V SC +K I R + +E L+A+
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 308 GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEAS 359
L C +G P+P + W K L+ RI + G+ + G Y C A
Sbjct: 140 ----LPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGSLRIHNVQKEDAGQYRCVAK 193
Query: 360 NCMGVAAS 367
N +G A S
Sbjct: 194 NSLGTAYS 201
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 64.9 bits (151), Expect = 4e-09
Identities = 74/288 (25%), Positives = 118/288 (40%), Gaps = 45/288 (15%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTNSL-------- 151
+E + A++ E + +F C V +P P +SW ++ +K D Y + L
Sbjct: 34 LETVDALVEE--VATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVED 91
Query: 152 ---GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G YCC A N +G A S L + K ++ K + GLK+V
Sbjct: 92 SDDGIYCCTANNGVGGAVESC--------GALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
P+PS+ W + D P+ E+SR + E G L I ++ D +++C
Sbjct: 140 -----LPCTTMGNPKPSVSWIKGDSPLRENSR--IAVLESGS--LRIHNVQKEDAGQYRC 190
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK 328
VA N G + + +KL + + R E+ V L C G+P P + W +
Sbjct: 191 VAKNSLGTAYSKV-VKLEVEVFARILRAPESHNVTFGS--FVTLHCTATGIPVPTITWIE 247
Query: 329 DGEELKPGDIHRIISGQ--DGTCSL-----GTYTCEASNCMGVAASSA 369
+G + G I + + D L G YTC A+N G S+A
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTA 295
Score = 47.2 bits (107), Expect = 0.001
Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 25/188 (13%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP L++V+A ++E F V P+P + W R ++ + + E G
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTR-NKILIKLFDTRYSIRENGQ-L 83
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSC-----FLKLIIPRHYKKPRFLENLQAILSDE 307
L I ++E D + C A N G +V SC +K I R + +E L+A+
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 308 GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEAS 359
L C +G P+P + W K L+ RI + G+ + G Y C A
Sbjct: 140 ----LPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGSLRIHNVQKEDAGQYRCVAK 193
Query: 360 NCMGVAAS 367
N +G A S
Sbjct: 194 NSLGTAYS 201
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 64.9 bits (151), Expect = 4e-09
Identities = 74/288 (25%), Positives = 118/288 (40%), Gaps = 45/288 (15%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTNSL-------- 151
+E + A++ E + +F C V +P P +SW ++ +K D Y + L
Sbjct: 34 LETVDALVEE--VATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVED 91
Query: 152 ---GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G YCC A N +G A S L + K ++ K + GLK+V
Sbjct: 92 SDDGIYCCTANNGVGGAVESC--------GALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
P+PS+ W + D P+ E+SR + E G L I ++ D +++C
Sbjct: 140 -----LPCTTMGNPKPSVSWIKGDSPLRENSR--IAVLESGS--LRIHNVQKEDAGQYRC 190
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK 328
VA N G + + +KL + + R E+ V L C G+P P + W +
Sbjct: 191 VAKNSLGTAYSKV-VKLEVEVFARILRAPESHNVTFGS--FVTLHCTATGIPVPTITWIE 247
Query: 329 DGEELKPGDIHRIISGQ--DGTCSL-----GTYTCEASNCMGVAASSA 369
+G + G I + + D L G YTC A+N G S+A
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTA 295
Score = 47.2 bits (107), Expect = 0.001
Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 25/188 (13%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP L++V+A ++E F V P+P + W R ++ + + E G
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTR-NKILIKLFDTRYSIRENGQ-L 83
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSC-----FLKLIIPRHYKKPRFLENLQAILSDE 307
L I ++E D + C A N G +V SC +K I R + +E L+A+
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 308 GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEAS 359
L C +G P+P + W K L+ RI + G+ + G Y C A
Sbjct: 140 ----LPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGSLRIHNVQKEDAGQYRCVAK 193
Query: 360 NCMGVAAS 367
N +G A S
Sbjct: 194 NSLGTAYS 201
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 64.9 bits (151), Expect = 4e-09
Identities = 74/288 (25%), Positives = 118/288 (40%), Gaps = 45/288 (15%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTNSL-------- 151
+E + A++ E + +F C V +P P +SW ++ +K D Y + L
Sbjct: 34 LETVDALVEE--VATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVED 91
Query: 152 ---GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G YCC A N +G A S L + K ++ K + GLK+V
Sbjct: 92 SDDGIYCCTANNGVGGAVESC--------GALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
P+PS+ W + D P+ E+SR + E G L I ++ D +++C
Sbjct: 140 -----LPCTTMGNPKPSVSWIKGDSPLRENSR--IAVLESGS--LRIHNVQKEDAGQYRC 190
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK 328
VA N G + + +KL + + R E+ V L C G+P P + W +
Sbjct: 191 VAKNSLGTAYSKV-VKLEVEVFARILRAPESHNVTFGS--FVTLHCTATGIPVPTITWIE 247
Query: 329 DGEELKPGDIHRIISGQ--DGTCSL-----GTYTCEASNCMGVAASSA 369
+G + G I + + D L G YTC A+N G S+A
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTA 295
Score = 47.2 bits (107), Expect = 0.001
Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 25/188 (13%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP L++V+A ++E F V P+P + W R ++ + + E G
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTR-NKILIKLFDTRYSIRENGQ-L 83
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSC-----FLKLIIPRHYKKPRFLENLQAILSDE 307
L I ++E D + C A N G +V SC +K I R + +E L+A+
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 308 GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEAS 359
L C +G P+P + W K L+ RI + G+ + G Y C A
Sbjct: 140 ----LPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGSLRIHNVQKEDAGQYRCVAK 193
Query: 360 NCMGVAAS 367
N +G A S
Sbjct: 194 NSLGTAYS 201
>AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 64.9 bits (151), Expect = 4e-09
Identities = 44/173 (25%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ +N+++ +Q K P+F+ +++ R KV+ P P + WY + + V
Sbjct: 234 RGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ 291
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
+ E+G+ L + + D + CVA N G++ + L ++ H + P F
Sbjct: 292 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 351
Query: 297 LENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGT 348
+ Q+ EG +V LEC++ +P P L W K E+ + RI QD T
Sbjct: 352 IYKPQSKKVLEGDSVKLECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNT 403
Score = 62.9 bits (146), Expect = 2e-08
Identities = 54/216 (25%), Positives = 103/216 (47%), Gaps = 31/216 (14%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
N + + + PRF++ + + +EG + KV G P P +SW+ +G+ ++ D+++
Sbjct: 238 NDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHK 297
Query: 145 LT----GTNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFS 190
+ G +SL G+Y C+AKN G+A+ + +L V L +E K
Sbjct: 298 MIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV------LAKEHK----- 346
Query: 191 KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERG 249
+AP F++ +S + + + +++ P P L W R+++ V + R L ++ G
Sbjct: 347 --RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTG 404
Query: 250 VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
L I+ + D + A N+ G VT+C +L
Sbjct: 405 RVTLLIKDVNKKDAGWYTVSAVNEAG--VTTCNTRL 438
Score = 47.6 bits (108), Expect = 7e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
Query: 287 IPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ 345
I + PRF++ + + DEG ++ KV G+P P + WY +G ++ D+H++I +
Sbjct: 243 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 302
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASL 371
G SL G Y C A N G A + L
Sbjct: 303 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL 338
>AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein
protein.
Length = 498
Score = 64.9 bits (151), Expect = 4e-09
Identities = 44/173 (25%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Query: 177 QNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
+ +N+++ +Q K P+F+ +++ R KV+ P P + WY + + V
Sbjct: 234 RGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ 291
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
+ E+G+ L + + D + CVA N G++ + L ++ H + P F
Sbjct: 292 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 351
Query: 297 LENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGT 348
+ Q+ EG +V LEC++ +P P L W K E+ + RI QD T
Sbjct: 352 IYKPQSKKVLEGDSVKLECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNT 403
Score = 62.9 bits (146), Expect = 2e-08
Identities = 54/216 (25%), Positives = 103/216 (47%), Gaps = 31/216 (14%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ 144
N + + + PRF++ + + +EG + KV G P P +SW+ +G+ ++ D+++
Sbjct: 238 NDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHK 297
Query: 145 LT----GTNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFS 190
+ G +SL G+Y C+AKN G+A+ + +L V L +E K
Sbjct: 298 MIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV------LAKEHK----- 346
Query: 191 KNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD-ESSRCHLGKEERG 249
+AP F++ +S + + + +++ P P L W R+++ V + R L ++ G
Sbjct: 347 --RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTG 404
Query: 250 VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
L I+ + D + A N+ G VT+C +L
Sbjct: 405 RVTLLIKDVNKKDAGWYTVSAVNEAG--VTTCNTRL 438
Score = 47.6 bits (108), Expect = 7e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
Query: 287 IPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ 345
I + PRF++ + + DEG ++ KV G+P P + WY +G ++ D+H++I +
Sbjct: 243 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 302
Query: 346 DGTCSL----------GTYTCEASNCMGVAASSASL 371
G SL G Y C A N G A + L
Sbjct: 303 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL 338
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 64.9 bits (151), Expect = 4e-09
Identities = 74/288 (25%), Positives = 118/288 (40%), Gaps = 45/288 (15%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTNSL-------- 151
+E + A++ E + +F C V +P P +SW ++ +K D Y + L
Sbjct: 34 LETVDALVEE--VATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVED 91
Query: 152 ---GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G YCC A N +G A S L + K ++ K + GLK+V
Sbjct: 92 SDDGIYCCTANNGVGGAVESC--------GALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
P+PS+ W + D P+ E+SR + E G L I ++ D +++C
Sbjct: 140 -----LPCTTMGNPKPSVSWIKGDSPLRENSR--IAVLESGS--LRIHNVQKEDAGQYRC 190
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK 328
VA N G + + +KL + + R E+ V L C G+P P + W +
Sbjct: 191 VAKNSLGTAYSKV-VKLEVEVFARILRAPESHNVTFGS--FVTLHCTATGIPVPTITWIE 247
Query: 329 DGEELKPGDIHRIISGQ--DGTCSL-----GTYTCEASNCMGVAASSA 369
+G + G I + + D L G YTC A+N G S+A
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTA 295
Score = 47.2 bits (107), Expect = 0.001
Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 25/188 (13%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP L++V+A ++E F V P+P + W R ++ + + E G
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTR-NKILIKLFDTRYSIRENGQ-L 83
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSC-----FLKLIIPRHYKKPRFLENLQAILSDE 307
L I ++E D + C A N G +V SC +K I R + +E L+A+
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 308 GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEAS 359
L C +G P+P + W K L+ RI + G+ + G Y C A
Sbjct: 140 ----LPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGSLRIHNVQKEDAGQYRCVAK 193
Query: 360 NCMGVAAS 367
N +G A S
Sbjct: 194 NSLGTAYS 201
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 64.9 bits (151), Expect = 4e-09
Identities = 212/1174 (18%), Positives = 501/1174 (42%), Gaps = 107/1174 (9%)
Query: 1926 ILQESLGETKQKIECDTNDEALD--IKAALMEMVEPLQNLHTQLIHVQEVVLSGVQEDSI 1983
+L+E+ ++ + + D + A E+ Q L + VQE + + + +
Sbjct: 816 VLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLN---EMEQL 872
Query: 1984 SLDIDSAESIVQTISDVHKKISAKLELETVNVSDKDVALIFEVDKDLHAIQDSIKALKNQ 2043
+++ +S +QT+ I+ KL+ +T+ ++V + + DL +Q+S++ ++Q
Sbjct: 873 KEQLENRDSTLQTVEREKTLITEKLQ-QTL----EEVKTLTQEKDDLKQLQESLQIERDQ 927
Query: 2044 PAAQDIKDVTKQIQDVEKSLHVLVASENVITDVKDKIPKGSTEQLVQHINQYXXXXXXXX 2103
DI D D ++ L + S + + + +E++ ++++
Sbjct: 928 -LKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKD 986
Query: 2104 XXXXXXXXXDLKETIEMAKDLRETFVTSDMINDEVAESIKEEI-LIEQARLAHKLQKAIS 2162
D K+ +E AK+ + +T+D+ ++E+ E ++ LI++ ++ +++
Sbjct: 987 EFQQKMVGIDKKQDLE-AKNTQT--LTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVI 1043
Query: 2163 ALQVQVFDSAQEMVPELSTEIFQRVARVTAQL--QADLMAVTGVHITIQAPPY--VLDEV 2218
A + Q+ +E + E++ E + + + +L Q +++A H + D +
Sbjct: 1044 AEKEQLKTDLKENI-EMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRL 1102
Query: 2219 AKSLETISTENRLVPESAQGDKLVSIVENVNMFENTADPPIQPKPKELSN--ITVEPEEV 2276
A+ E + +++ + E Q +L+++ E ++ + + I+ EL N +T+E E
Sbjct: 1103 AEVEEKLKEKSQQLQEKQQ--QLLNVQEEMSEMQKKINE-IENLKNELKNKELTLEHMET 1159
Query: 2277 NITQLLEDVSSNERVINENLVTVTQEVAVAQ-----METNMD-IAGVTKKTQ-DGL-IKD 2328
+L + ++ N E + ++T+E V + ET D + G ++ + GL K+
Sbjct: 1160 ERLELAQKLNENY----EEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE 1215
Query: 2329 DIK--SFSISEEAQSIFE---QGSPEVYNVLNAEELASNQTFSADSASNNMPDNELDIVE 2383
++K + E ++I E S + ++N ++L + T + + E +++
Sbjct: 1216 ELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIP--VLHEEQELLP 1273
Query: 2384 PVLVCSVPASSLDDLEGSVNPKT--GLVTDEKIDLQKVDVTIEMPE----IAQLDKCQPF 2437
V S ++++LE T T +I+++++ + + E I L K +
Sbjct: 1274 NVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDN 1333
Query: 2438 YANLHELM-----QSVDLAKQLQKSITISESVIEPNIETEPNPQSPVYLAS---QLKMAL 2489
+ E + Q + ++ I S+S E ++ + + S Q K
Sbjct: 1334 LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKD 1393
Query: 2490 LVLYNQDIESLEVMAP-HLTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESV 2548
L +IE L + + D++K +++ DDL ++ E +QS + + ++KE
Sbjct: 1394 SALLRIEIEMLGLSKRLQESHDEMKSVAKEK----DDLQRLQEVLQSESDQLKENIKE-- 1447
Query: 2549 QKANVVEQDLNSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIK 2608
+V + L + EE+ ++ QE + V K +++
Sbjct: 1448 ----IVAKHLETEEEL-KVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQ 1502
Query: 2609 SVVGKITDNLFSIEAAQSIEVKEDFSDVK--STDLRVTDSVTEVLESSDVRVIENVSKSD 2666
+ + +I + Q EV+E +++K + DS + +ES +++E ++
Sbjct: 1503 NKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIES---KMLELTNRLQ 1559
Query: 2667 DVPTNINLLVDDSLLEIDKAVKSTEALKNIPQRDLAENEQQLGEDTTGSKQKVVE-LPDT 2725
+ I +++ E ++ + EAL+ I + L EN +++ S++K + L T
Sbjct: 1560 ESQEEIQIMIK----EKEEMKRVQEALQ-IERDQLKENTKEIVAKMKESQEKEYQFLKMT 1614
Query: 2726 IDDVSQDMI--VEHLPTS-EVKLLEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSV 2782
+ +Q+ + +EHL E + L + + E L++ L +L ++ T+ D SV
Sbjct: 1615 AVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSV 1674
Query: 2783 DLVKIAGEPEIKSKLVEELQTIADSKSQKMIEESTTRETVESPLITTGKTTETPNDITSM 2842
+ ++K L E + + + + I +E E+ G +E N+I++M
Sbjct: 1675 EETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNM 1734
Query: 2843 NVGETEKQRKESITELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDL 2902
+K+ + S+D K+Q + + +E+ + H+ +K +E +
Sbjct: 1735 --------QKDL-----EHSNDALKAQDL--KIQEELRIAHM---HLKEQQETIDKLRGI 1776
Query: 2903 TAEVNLPLVTGHETIQTLNSNLENEMCESLKIEQAVSAETTESTVESQRVASEVILELVS 2962
+E L + ++ N+ L+ E + LK + + E+Q+ SE +E +
Sbjct: 1777 VSEKTDKLSNMQKDLENSNAKLQ-EKIQELKANEHQLITLKKDVNETQKKVSE--MEQLK 1833
Query: 2963 EQLKKDQAESSNSQTAENIVREIVVTSEITALETLGLPLERSGNDGDLVELLSIETKQIT 3022
+Q+ KDQ+ + + EN+ + + ++++ + + ++L + K+
Sbjct: 1834 KQI-KDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESL 1892
Query: 3023 VEPRATTYEVVAEQQVVPS-GQQPVEAIDSMKKE 3055
E +A E+ E + ++ E +D ++++
Sbjct: 1893 QETKARDLEIQQELKTARMLSKEHKETVDKLREK 1926
Score = 53.2 bits (122), Expect = 1e-05
Identities = 132/662 (19%), Positives = 261/662 (39%), Gaps = 57/662 (8%)
Query: 2266 LSNITVEPEEVN-ITQLLEDVSSNERVINENLVTVTQEVAVAQMETNMDIAGVTKKTQDG 2324
LS + P EV + + ++D S +I + EV + + + K T+D
Sbjct: 726 LSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGK-TKDD 784
Query: 2325 LIKDDIKSFSISEEAQSI--FEQGSPEVYNVLNAEELASNQTFSADSASNNMPDNELDIV 2382
L S +E Q+ + Y ++ E NQ S D+ L +
Sbjct: 785 LATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGAL 844
Query: 2383 EPVLVCSVPASSLDDLEGSVNPKTGLVTDEKIDLQKVDVTIEMPEIAQL---DKCQPFYA 2439
+ L S L + V + + K L+ D T++ E + +K Q
Sbjct: 845 KTEL--SYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLE 902
Query: 2440 NLHELMQSVDLAKQLQKSITISESVIEPNIETEPNPQSPVYLASQLKMALLVLYNQDIES 2499
+ L Q D KQLQ+S+ I ++ +I N + QL+ AL L Q E+
Sbjct: 903 EVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMN--IDTQEQLRNALESL-KQHQET 959
Query: 2500 LEVMAPHLTKDKLKVI--SEIVHNLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVEQD 2557
+ + ++++ + + E D+ Q M + Q+ + + A+V + +
Sbjct: 960 INTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQ--TLTADVKDNE 1017
Query: 2558 -LNSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKITD 2616
+ +I + + K LQ++ ++++ TI+ E ++G
Sbjct: 1018 IIEQQRKIFSLIQEKNELQQM--LESVIAEKEQLKTDLKENIEMTIENQEELRLLGD--- 1072
Query: 2617 NLFSIEAAQSIEVKEDFSDVKSTD--LRVTDSVTEVLESSDVRVIENVSKSDDVPTNINL 2674
++ Q I +E +K R D + EV E + + K + L
Sbjct: 1073 ---ELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL-----L 1124
Query: 2675 LVDDSLLEIDKAVKSTEALKN-IPQRDLAENEQQLGEDTTGSKQKVVELPDTIDDVSQD- 2732
V + + E+ K + E LKN + ++L + + + QK+ E + + ++++
Sbjct: 1125 NVQEEMSEMQKKINEIENLKNELKNKEL--TLEHMETERLELAQKLNENYEEVKSITKER 1182
Query: 2733 MIVEHLPTS---EVKLLEGQLLAAEENTL--SEALKSSLVTVQKTTET------PLDDTS 2781
+++ L S E L G + E L E LK + + +++ ET + + +
Sbjct: 1183 KVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKT 1242
Query: 2782 VDLVKIAGEPEIKSKLVEELQTIADSKS--QKMIEESTTRETV-ESPLITTGKTTETPND 2838
++ + +KL EE+ + + + + E S T+ET+ E L+T TT+ D
Sbjct: 1243 AQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTK---D 1299
Query: 2839 ITSMNVGETEKQR-KESITELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQL 2897
T++ E E+ R E E ++ TK + + + + + V+H D++K + L
Sbjct: 1300 STTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKH---DQLKEHIRETL 1356
Query: 2898 AK 2899
AK
Sbjct: 1357 AK 1358
Score = 52.4 bits (120), Expect = 2e-05
Identities = 263/1376 (19%), Positives = 561/1376 (40%), Gaps = 147/1376 (10%)
Query: 1640 IEEVEHNIAVLEEY--DFVDLSRASELSSCASPQIAKEVEIESLVHISEIVETAVRIIKD 1697
+ EV + A+L+ Y + +DL + E S + A E + +++++E + K
Sbjct: 340 VNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKD-----QLAQLLEEKDLLQKV 394
Query: 1698 AGEDTPMADLMIVEDFFTTCKNEFTILRCLLNKSMSPKKIIRLVQEFCNIQSTIQ-GFKT 1756
E M+V T + E R + KI ++ QS I T
Sbjct: 395 QNEKIENLTRMLVTSSSLTLQQELKAKR-KRRVTWCLGKINKMKNSNYADQSNIPTNITT 453
Query: 1757 KTNELQLSDDVNQCIESFLIHSDDCLATVRQSLIKIVESQSELLFKSPIVNLKYLSHRNH 1816
KT++L ++ + + I+ + D + +L +I + + L + + S R
Sbjct: 454 KTHKLSIN--LLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRAD 511
Query: 1817 FDKMANLVAKLDDFVDAVKPNAENIKDKIIM-ELKNLDLCNVNNEENKLVRTMDDFFRFV 1875
+D NLV + + +K+K + E + L+ ++EN+L ++ R
Sbjct: 512 YD---NLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQENELSSKVE-LLREK 567
Query: 1876 EDEIV-VQE--DNDKKVILKKILT-CLEKDRDYKDATDAGKVLIIMHCLSNCVDILQESL 1931
ED+I +QE D+ K +K L+ LE D K + + +D +ES
Sbjct: 568 EDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQT-----LFDAETVALDAKRESA 622
Query: 1932 GETKQKIECDTNDEALDIKAALMEMVEPLQNLHTQLIHVQEVVLSGVQE-DSISLDIDSA 1990
+ +E ++ ++ +M +Q +QL +++ + +E S +I
Sbjct: 623 FLRSENLEL--KEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKL 680
Query: 1991 ESIVQTISDVHKKISAKLELETVNVSDKDVALIFEVDKDLHAIQDSIKALKNQPAAQDIK 2050
S++ V K + LELE ++D L EV+++ ++ I + + +++
Sbjct: 681 TSLID--GKVPKDLLCNLELEG-KITDLQKELNKEVEENEALREEVILLSELKSLPSEVE 737
Query: 2051 DVTKQIQDVEKSLHVLVA-SENVITDVKDKIPKGSTEQLVQHINQYXXXXXXXXXXXXXX 2109
+ K+IQD + LH++ + + + ++V K + + L++ I +
Sbjct: 738 RLRKEIQDKSEELHIITSEKDKLFSEVVHK--ESRVQGLLEEIGK-----TKDDLATTQS 790
Query: 2110 XXXDLKETIEMAKDLRETFVTSDMINDEVAESIKEEILIEQARLAHKLQKAISALQVQVF 2169
+ + K L F + E E + +EI + ++ A K ++ AL+ ++
Sbjct: 791 NYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEI-VNLSKEAQKFDSSLGALKTELS 849
Query: 2170 DSAQEMVPELSTEIFQRVARVTAQLQADLMAVTGVHITIQAPPYVLDEVAKSLETISTEN 2229
QE+ E + E+ +R+ + QL+ L T++ ++ E K +T+
Sbjct: 850 YKTQEL-QEKTREVQERLNEM-EQLKEQLENRDSTLQTVEREKTLITE--KLQQTLEEVK 905
Query: 2230 RLVPESAQGDKLVSIVENVNMFENTADPPIQPKPKELSNITVEPEEVNITQLLEDVSSNE 2289
L E D L + E++ + + I + N+ ++ +E + LE + ++
Sbjct: 906 TLTQEK---DDLKQLQESLQIERDQLKSDIH----DTVNMNIDTQE-QLRNALESLKQHQ 957
Query: 2290 RVINENLVTVTQEVAVAQMETNMDIAGVTKKTQDGLIKDDIKSFSISEEAQSIFEQGSPE 2349
IN +++EV+ N+ + T +T+D + K I ++ Q +
Sbjct: 958 ETINTLKSKISEEVS-----RNLHMEENTGETKDEFQQ---KMVGI-DKKQDL------- 1001
Query: 2350 VYNVLNAEELASNQTFSADSASNNMPDNELDIVEPVLVCSVPASSLDDLEGSVNPKTGLV 2409
E + QT +AD N + + + I + LE + K L
Sbjct: 1002 --------EAKNTQTLTADVKDNEIIEQQRKIFS---LIQEKNELQQMLESVIAEKEQLK 1050
Query: 2410 TDEKIDLQKVDVTIEMPEIA-----QLDKCQPFYA--NLHELMQSVDLAKQLQKSITISE 2462
TD K + +++TIE E +L K Q A H + + +L++ + + E
Sbjct: 1051 TDLK---ENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEE 1107
Query: 2463 SVIEPNIETEPNPQSPVYLASQLKMALLVLYNQDIESL--EVMAPHLTKDKLKVISEIVH 2520
+ E + + + Q L Q +M+ + +IE+L E+ LT + ++ +E +
Sbjct: 1108 KLKEKSQQLQEKQQQ--LLNVQEEMSEMQKKINEIENLKNELKNKELTLEHME--TERL- 1162
Query: 2521 NLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVEQDLNSPEEIDEIFETKTPLQEVGTA 2580
L L + E V+S T E V + +QK+ E+D + I EI T +E
Sbjct: 1163 ELAQKLNENYEEVKS--ITKERKVLKELQKSFETERD-HLRGYIREIEATGLQTKEELKI 1219
Query: 2581 QNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKITDNLFSIEAAQSIEVKEDFSDVKSTD 2640
+I ETID E++ V + T + + + + K +
Sbjct: 1220 AHI----------HLKEHQETID--ELRRSVSEKTAQIINTQDLEKSHTK------LQEE 1261
Query: 2641 LRVTDSVTEVLESSDVRVIENVSKSDDVPTNINLLVDDSLLEIDKAVKSTEALKNIPQRD 2700
+ V E+L + ++ VS++ + + LL + S + D + ++ + +
Sbjct: 1262 IPVLHEEQELLPN-----VKEVSETQETMNELELLTEQSTTK-DSTTLARIEMERLRLNE 1315
Query: 2701 LAENEQQLGEDTTGSKQKVVELPDTIDDVSQDMIVEHLPTSEVKLLEGQLLAAEENTLSE 2760
+ Q+ + T + + + + + +V D + EH+ + K+ E Q + + E
Sbjct: 1316 KFQESQEEIKSLTKERDNLKTIKEAL-EVKHDQLKEHIRETLAKIQESQSKQEQSLNMKE 1374
Query: 2761 ALKSSLVTVQKTTE-TPLDDTSVDL-VKIAGEPEIKSKLVEELQTIADSKS--QKMIE-- 2814
+ V + + P D + + +++ G + + +E++++A K Q++ E
Sbjct: 1375 KDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVL 1434
Query: 2815 ESTTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESITELNQKSSDFTKSQSIVSD 2874
+S + + E+ K ET ++ + K+++E+I EL S+ ++ +S
Sbjct: 1435 QSESDQLKENIKEIVAKHLETEEELKVAHC--CLKEQEETINELRVNLSE---KETEIST 1489
Query: 2875 VSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTG-HETIQTLNSNLENEMCESLK 2933
+ +++ I+D+++ ++ KE+ + N+ ++ E + L E+ +
Sbjct: 1490 IQKQL---EAINDKLQNKIQEIYEKEE---QFNIKQISEVQEKVNELKQFKEHRKAKDSA 1543
Query: 2934 IEQAVSAETTESTVESQRVASEV-ILELVSEQLKKDQ--AESSNSQTAENIVREIV 2986
+ Q++ ++ E T Q E+ I+ E++K+ Q + Q EN +EIV
Sbjct: 1544 L-QSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKEN-TKEIV 1597
Score = 52.4 bits (120), Expect = 2e-05
Identities = 228/1270 (17%), Positives = 509/1270 (40%), Gaps = 122/1270 (9%)
Query: 1747 IQSTIQGFKTKTNELQLSDDVNQCIESFLIHSDDCLATVRQSLIKIVESQSELLFKSPIV 1806
+Q T++ KT T E DD+ Q ES I D + + ++ +++Q +L ++ +
Sbjct: 897 LQQTLEEVKTLTQE---KDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQL--RNALE 951
Query: 1807 NLKYLSHRNHFDKMANLVAKLDDFVDA---VKPNAENIKD----KII-------MELKNL 1852
+LK H + + L +K+ + V ++ N KD K++ +E KN
Sbjct: 952 SLK-----QHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNT 1006
Query: 1853 DLCNVNNEENKLVRTMDDFFRFVEDEIVVQEDNDKKVILKKILTCLEKDRDYKDATDAGK 1912
+ ++N+++ F ++++ +Q+ + + K+ L K+ + +
Sbjct: 1007 QTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEE 1066
Query: 1913 VLIIMHCLSNCVDIL-QESLGETKQKIECD-TNDEALDIKAALMEMVEPLQNLHTQLIHV 1970
+ ++ L +I+ QE K++ E T D +++ L E + LQ QL++V
Sbjct: 1067 LRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNV 1126
Query: 1971 QEVVLSGVQEDSISLDIDSAESIVQTISDVHKKISAKLEL-ETVNVSDKDVALIFEVDKD 2029
QE +S +Q+ ++ E + ++ H + + +LEL + +N + ++V I + K
Sbjct: 1127 QE-EMSEMQKKINEIENLKNELKNKELTLEHME-TERLELAQKLNENYEEVKSITKERKV 1184
Query: 2030 LHAIQDSIKALKN--QPAAQDIKDVTKQIQDVEKSLHVLVASENVITDVKDKIPKGSTEQ 2087
L +Q S + ++ + ++I+ Q ++ K H+ + + D++ + +E+
Sbjct: 1185 LKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQ---ETIDELRRSVSEK 1241
Query: 2088 LVQHINQYXXXXXXXXXXXXXXXXXDLKETIEMAKDLRETFVTSDMINDEVAESIKEEIL 2147
Q IN L E E+ +++E T + +N+ E + E+
Sbjct: 1242 TAQIINTQDLEKSHTKLQEEIPV---LHEEQELLPNVKEVSETQETMNE--LELLTEQST 1296
Query: 2148 IEQARLAHKLQKAISALQVQVFDSAQEMVPELSTEIFQRVARVTAQLQADLMAVTGVHIT 2207
+ + +++ L + F +QE + L+ E L+ A+ H
Sbjct: 1297 TKDSTTLARIEMERLRLN-EKFQESQEEIKSLTKE--------RDNLKTIKEALEVKH-- 1345
Query: 2208 IQAPPYVLDEVAKSLETISTENRLVPESAQGDKLVSIVENVNMFENTADPPIQPKPKELS 2267
Q ++ + +AK E+ S + + + + ++ IV + F KPK+ +
Sbjct: 1346 DQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQF----------KPKDSA 1395
Query: 2268 NITVEPEEVNITQLLEDVSSNERVINENLVTVTQEVAVAQMETNM---DIAGVTKKTQDG 2324
+ +E E + +++ L++ + + + + + V Q E++ +I + K +
Sbjct: 1396 LLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLET 1455
Query: 2325 LIKDDIKSFSISEEAQSIFEQGSPEVYNVLNAEELASNQTFSADSASNNMPDNELDIVEP 2384
+ + + E+ ++I E N+ E S ++ ++ + + +I E
Sbjct: 1456 EEELKVAHCCLKEQEETINELR----VNLSEKETEISTIQKQLEAINDKLQNKIQEIYEK 1511
Query: 2385 VLVCSVPASSLDDLEGSVNPKTGLVTDEKIDLQKVDVTIEMPEIAQLDKCQPFYANLHEL 2444
++ + +++ VN K + +IE + ++ Q + +
Sbjct: 1512 EEQFNI--KQISEVQEKVNELKQFKEHRKAKDSALQ-SIESKMLELTNRLQESQEEIQIM 1568
Query: 2445 MQSVDLAKQLQKSITISESVIEPNIE--TEPNPQSPVYLASQLKMALLVLYNQDIESLEV 2502
++ + K++Q+++ I ++ N + +S LKM + + + +E
Sbjct: 1569 IKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEH 1628
Query: 2503 MAPHLTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVEQDLNSPE 2562
+ KL + + N+ LTQ++ N S KE DL S E
Sbjct: 1629 LKEQFETQKLNLENIETENI--RLTQIL---HENLEEMRSVTKE--------RDDLRSVE 1675
Query: 2563 EIDEI--FETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKITDNLFS 2620
E ++ + K L+E T ETID +++ +V + T+ + +
Sbjct: 1676 ETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETID--KLRGIVSEKTNEISN 1733
Query: 2621 IEAAQSIEVKEDFSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPTNINLLVDDSL 2680
++ + +E D +K+ DL+ + E L + + + E D + I D L
Sbjct: 1734 MQ--KDLEHSND--ALKAQDLK----IQEELRIAHMHLKEQQETIDKL-RGIVSEKTDKL 1784
Query: 2681 LEIDKAVKSTEALKNIPQRDLAENEQQ---LGEDTTGSKQKVVELPDTIDDV-SQDMIVE 2736
+ K ++++ A ++L NE Q L +D +++KV E+ + Q + +
Sbjct: 1785 SNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLS 1844
Query: 2737 HLPTSEVKL-------LEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAG 2789
L + L LE +E ++ +L + + L +T ++I
Sbjct: 1845 KLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQ 1904
Query: 2790 EPEIKSKLVEELQTIADSKSQKMIEESTTRETVESPLITTGKTTETPNDITSMNV----- 2844
E + L +E + D +K+ E++ ++ L + + D + V
Sbjct: 1905 ELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKQDRQNHQVKPEKR 1964
Query: 2845 --GETEKQRKESITELNQKSSDFTKSQSIVSDVSQEILVEHL-ISDEIKFTKEQQLAKED 2901
+ ++ ES+ E + + K S + D + + L + EI+F KE +
Sbjct: 1965 LLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMR--- 2021
Query: 2902 LTAEVNLP-LVTGH-ETIQTLNSNLENEMCESLKIEQAVSAETTESTVESQRVASEVILE 2959
+ A ++LP L T H E + T N E +K + V + T+ E ++ ++
Sbjct: 2022 VKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMD 2081
Query: 2960 LVSEQLKKDQ 2969
+ E K+ +
Sbjct: 2082 FIDEVEKQKE 2091
Score = 48.4 bits (110), Expect = 4e-04
Identities = 117/581 (20%), Positives = 240/581 (41%), Gaps = 44/581 (7%)
Query: 745 EIISSLINPLSEILSITDTIQESASETIEVQRTLFSRLPKPLKVLQQTLTIIEKCIDVES 804
E+ L + ++E + ++E+ TIE Q L L LK QQ + EK ++
Sbjct: 1034 ELQQMLESVIAEKEQLKTDLKENIEMTIENQEEL-RLLGDELKK-QQEIVAQEKNHAIKK 1091
Query: 805 DNRTLVKKTC---VSIMEKCGNAIQNLVS-EINAIEKKEYLLLSENVCNELDVVSNEIS- 859
+ + +TC + EK Q L + + +E + + NE++ + NE+
Sbjct: 1092 EGE--LSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKN 1149
Query: 860 ---TVVNFSTESIKTNNLLNETTEVKLESTVESKHLTDTQKALFELKGPLRSLLYIVDSA 916
T+ + TE ++ LNE E T E K L + QK+ + LR YI +
Sbjct: 1150 KELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRG--YIREIE 1207
Query: 917 ESGKIVDISQVNNSEVILNDMSASIQDLQSALEQIESLSVLECATSLNKYNTEIIENVME 976
+G + ++ + + L + +I +L+ ++ E + + L K +T++ E +
Sbjct: 1208 ATG-LQTKEELKIAHIHLKEHQETIDELRRSVS--EKTAQIINTQDLEKSHTKLQEEI-- 1262
Query: 977 PVLQLRSSFEKMSTEIKAEDKIQLNKVLSSIKENLTVISSYINKVENNIGAFDVLQNENK 1036
PVL E+ +E + +N++ +++ T S+ + ++E + L+ K
Sbjct: 1263 PVLHEEQELLPNVKEV-SETQETMNELELLTEQSTTKDSTTLARIE-----MERLRLNEK 1316
Query: 1037 LEALQKMAETLISLEKNLPTLDTMPQVQGNMNSFHKNLTKALEKVIESNNANKYLSMIEI 1096
+ Q+ ++L NL T+ +V+ + H + + L K+ ES +K + +
Sbjct: 1317 FQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEH--IRETLAKIQESQ--SKQEQSLNM 1372
Query: 1097 CDGIRRINSCIRDMDTDNILSLASLSNTLKIIQNQFIKNIFDSELNCCVVTNITDILIGI 1156
+ + +M+ A L ++++ K + +S V D L +
Sbjct: 1373 KEKDNETTKIVSEMEQFKPKDSALLRIEIEML--GLSKRLQESHDEMKSVAKEKDDLQRL 1430
Query: 1157 QETINQAQEFTTEIQYDNFQDTQAPIFDSTKVEIIVEH--VNQTVAAINQVKLLETTSSL 1214
QE + + E N ++ A + T+ E+ V H + + IN+ L S
Sbjct: 1431 QEVLQSESDQLKE----NIKEIVAKHLE-TEEELKVAHCCLKEQEETINE---LRVNLSE 1482
Query: 1215 KENITPTLQKICPILEELKQNIASACVGGIQK--EAYVSDISEK-SFSEKFAVPLSELNH 1271
KE T+QK + + QN ++ +S++ EK + ++F +
Sbjct: 1483 KETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDS 1542
Query: 1272 NVIVLNQTIIENIESLKESNEIVTAIAEPLQELFRTLEVIQ 1312
+ + ++E L+ES E + + + +E+ R E +Q
Sbjct: 1543 ALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQ 1583
Score = 42.7 bits (96), Expect = 0.020
Identities = 216/1189 (18%), Positives = 462/1189 (38%), Gaps = 101/1189 (8%)
Query: 836 EKKEYLLLSENVCNELDVVS-NEISTVVNFSTESIKTNNLLNETTEVKLESTVESKHLTD 894
E+K ++L EN ++V+ ++ + + S ++KT L+ T+ E T E + +
Sbjct: 810 EQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTE--LSYKTQELQEKTREVQERLN 867
Query: 895 TQKALFELKGPLRSLLYIVDSAESGKIVDISQVNNSEVILNDMSASIQDLQSAL--EQIE 952
+ L E S L V+ ++ + Q L ++ LQ +L E+ +
Sbjct: 868 EMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQ 927
Query: 953 SLSVLECATSLNKYNTEIIENVMEPVLQLRSSFEKMSTEIKAEDKIQLN------KVLSS 1006
S + ++N E + N +E + Q + + + ++I E L+ +
Sbjct: 928 LKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDE 987
Query: 1007 IKENLTVISSYINKVENNIGAFDVLQNENKLEALQKMAETLISLEKNLPTLDTMPQVQGN 1066
++ + I + N +N++ Q+ +LI + L + + V
Sbjct: 988 FQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQM--LESVIAE 1045
Query: 1067 MNSFHKNLTKALEKVIESNNANKYLSMIEICDGIRRINSCIRDMDTDNILSLASLSNT-- 1124
+L + +E IE+ + L D +++ + I LS T
Sbjct: 1046 KEQLKTDLKENIEMTIENQEELRLLG-----DELKKQQEIVAQEKNHAIKKEGELSRTCD 1100
Query: 1125 -LKIIQNQFIKNIFDSELNCCVVTNITDILIGIQETINQAQEFTTEIQYDNFQDTQAPIF 1183
L ++ + + + + N+ + + +Q+ IN+ + E++ ++
Sbjct: 1101 RLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKN---KELTLEHM 1157
Query: 1184 DSTKVEIIVEHVNQTVAAINQV-KLLETTSSLKENITPTLQKICPILEELK----QNIAS 1238
++ ++E+ + +N+ + + K + L+++ + + E++ Q
Sbjct: 1158 ETERLEL-AQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEE 1216
Query: 1239 ACVGGIQKEAYVSDISE--KSFSEKFAVPLSELNHNVIVLNQTIIENIESLKESNEIVTA 1296
+ I + + I E +S SEK A ++ ++ + + E I L E E++
Sbjct: 1217 LKIAHIHLKEHQETIDELRRSVSEKTAQIIN--TQDLEKSHTKLQEEIPVLHEEQELLPN 1274
Query: 1297 IAE--PLQELFRTLEVIQQDVISQFGPDLSPYEISVDIASIIQSLQSCVVMIQDHAAIEV 1354
+ E QE LE++ + ++ L+ I ++ + + Q I+ + +
Sbjct: 1275 VKEVSETQETMNELELLTEQSTTKDSTTLA--RIEMERLRLNEKFQESQEEIK--SLTKE 1330
Query: 1355 VDDMSTLEDISGIKTTAETASADQLVLPTAEFATT-EQTLGSFYDEQPKSSIAQALHVLN 1413
D++ T+++ +K + + E + EQ+L + + I +
Sbjct: 1331 RDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFK 1390
Query: 1414 EHLTILQSPEIIDAIDTLSEISD-YSSLKSVTLGLSDLHSGIEEVLQPI---VLEGLQSI 1469
+ L EI + + + + + +KSV DL ++EVLQ + E ++ I
Sbjct: 1391 PKDSALLRIEI-EMLGLSKRLQESHDEMKSVAKEKDDLQR-LQEVLQSESDQLKENIKEI 1448
Query: 1470 NASKLAAMAEPMQVLQHSLSVVDPNNIPIYENILELLTDNIHSVLNKINAFKEHLDKCMQ 1529
A L E ++V L + + N+ E T+ I ++ ++ A + L +Q
Sbjct: 1449 VAKHLET-EEELKVAHCCLKEQEETINELRVNLSEKETE-ISTIQKQLEAINDKLQNKIQ 1506
Query: 1530 AILPALE-FT-KQSIEISSSVNKLREACQHLKIMLKSINQSSTTQIPEVQVLDDVVNEIL 1587
I E F KQ E+ VN+L++ +H K ++ + + L + EI
Sbjct: 1507 EIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQ 1566
Query: 1588 IATDVTEGIKIEQVRYLSEELYARVAGVREEILRFTPNSSEALPNEASFIH--TIEEVEH 1645
I + E+++ + E L ++E E+ E F+ + E +
Sbjct: 1567 IMIK-----EKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQE 1621
Query: 1646 NIAVLEEYDFVDLSRASELSSCASPQIAKE-VEIESLVHISEIVETAVRIIKDAGEDTPM 1704
+ +E L E I E + + ++H E +E + K+ + +
Sbjct: 1622 KMCEIEH-----LKEQFETQKLNLENIETENIRLTQILH--ENLEEMRSVTKERDDLRSV 1674
Query: 1705 ADLMIVEDFFTTCKNEFTILRCLLNKSMSPKKIIRL-VQEFCNIQSTIQGF-KTKTNELQ 1762
+ + VE TI R L + KI+ + ++E ++G KTNE+
Sbjct: 1675 EETLKVERDQLKENLRETITRDL--EKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEI- 1731
Query: 1763 LSDDVNQCIESFLIHSDDCLATVRQSLIKIVESQSELLFKSPIVNLKYLSHRNHFDKMAN 1822
++ L HS+D L + +KI Q EL I ++ + DK+
Sbjct: 1732 ------SNMQKDLEHSNDAL---KAQDLKI---QEEL----RIAHMHLKEQQETIDKLRG 1775
Query: 1823 LVAKLDDFVDAVKPNAENIKDKI---IMELKN-----LDLCNVNNEENKLVRTMDDFFRF 1874
+V++ D + ++ + EN K+ I ELK + L NE K V M+ +
Sbjct: 1776 IVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQ 1835
Query: 1875 VEDEIVV--QEDNDKKVILKKILTCLEKDRDYKDATDAGKVLIIMHCLSNCVDILQESLG 1932
++D+ + + + + + +K+ LE+ + D + + L D L+ESL
Sbjct: 1836 IKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERD--NLRRVEETLKLERDQLKESLQ 1893
Query: 1933 ETKQKIECDTNDEALDIKAALMEMVEPLQNLHTQLIHVQEVVLSGVQED 1981
ETK + + + E + E E + L + I + + +S +Q+D
Sbjct: 1894 ETKAR-DLEIQQELKTARMLSKEHKETVDKLR-EKISEKTIQISDIQKD 1940
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 63.7 bits (148), Expect = 1e-08
Identities = 67/287 (23%), Positives = 124/287 (43%), Gaps = 45/287 (15%)
Query: 105 QAVLTEEGL-VSFECKVVGFPTPVLSWFK-DGQEL-------KPGDVYQLTG--TNSLGS 153
+ V T +G V EC +G P P + W + DG+ + K + ++ G
Sbjct: 233 ETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGL 292
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A+N G+ + +LT +++ P ++ + + ++E
Sbjct: 293 YECVAENSRGKNVARGQLT---------------FYAQ---PNWIQKINDIHVAMEENVF 334
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
+ K P+P+ W ++ +P+ R + E+G L+I + D ++C+A N
Sbjct: 335 WECKANGRPKPTYKWLKNGEPLLTRDRIQI---EQGT--LNITIVNLSDAGMYQCLAENK 389
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G ++ L +I L+ + ++ G V +ECK P+PV W K + L
Sbjct: 390 HGVIFSNAELSVIAVGPDFSRTLLKRV-TLVKVGGEVVIECKPKASPKPVYTWKKGRDIL 448
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASLL 372
K + RI +DG + G+YTC A+N G A+S+ +L+
Sbjct: 449 KENE--RITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLV 493
Score = 44.0 bits (99), Expect = 0.009
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 10/89 (11%)
Query: 95 YRKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL-TGT---- 148
Y +P +++ + + + E V +ECK G P P W K+G+ L D Q+ GT
Sbjct: 313 YAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNIT 372
Query: 149 ----NSLGSYCCIAKNCMGQASSSAELTV 173
+ G Y C+A+N G S+AEL+V
Sbjct: 373 IVNLSDAGMYQCLAENKHGVIFSNAELSV 401
Score = 41.9 bits (94), Expect = 0.035
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 8/78 (10%)
Query: 305 SDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHR--------IISGQDGTCSLGTYTC 356
S+E V L C+V G P+P ++W +G ++ G R +I+ + T GTY C
Sbjct: 41 SEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQC 100
Query: 357 EASNCMGVAASSASLLGF 374
A+N G S + L F
Sbjct: 101 TATNSFGTIVSREAKLQF 118
Score = 40.7 bits (91), Expect = 0.081
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCCIAKNC 161
G V ECK P PV +W K LK + ++ +L GSY CIA N
Sbjct: 423 GEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNH 482
Query: 162 MGQASSSAELTVED 175
G ASS+ L V+D
Sbjct: 483 FGTASSTGNLVVKD 496
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 63.7 bits (148), Expect = 1e-08
Identities = 67/287 (23%), Positives = 124/287 (43%), Gaps = 45/287 (15%)
Query: 105 QAVLTEEGL-VSFECKVVGFPTPVLSWFK-DGQEL-------KPGDVYQLTG--TNSLGS 153
+ V T +G V EC +G P P + W + DG+ + K + ++ G
Sbjct: 233 ETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGL 292
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y C+A+N G+ + +LT +++ P ++ + + ++E
Sbjct: 293 YECVAENSRGKNVARGQLT---------------FYAQ---PNWIQKINDIHVAMEENVF 334
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
+ K P+P+ W ++ +P+ R + E+G L+I + D ++C+A N
Sbjct: 335 WECKANGRPKPTYKWLKNGEPLLTRDRIQI---EQGT--LNITIVNLSDAGMYQCLAENK 389
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
G ++ L +I L+ + ++ G V +ECK P+PV W K + L
Sbjct: 390 HGVIFSNAELSVIAVGPDFSRTLLKRV-TLVKVGGEVVIECKPKASPKPVYTWKKGRDIL 448
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASLL 372
K + RI +DG + G+YTC A+N G A+S+ +L+
Sbjct: 449 KENE--RITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLV 493
Score = 44.0 bits (99), Expect = 0.009
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 10/89 (11%)
Query: 95 YRKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL-TGT---- 148
Y +P +++ + + + E V +ECK G P P W K+G+ L D Q+ GT
Sbjct: 313 YAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNIT 372
Query: 149 ----NSLGSYCCIAKNCMGQASSSAELTV 173
+ G Y C+A+N G S+AEL+V
Sbjct: 373 IVNLSDAGMYQCLAENKHGVIFSNAELSV 401
Score = 41.9 bits (94), Expect = 0.035
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 8/78 (10%)
Query: 305 SDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHR--------IISGQDGTCSLGTYTC 356
S+E V L C+V G P+P ++W +G ++ G R +I+ + T GTY C
Sbjct: 41 SEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQC 100
Query: 357 EASNCMGVAASSASLLGF 374
A+N G S + L F
Sbjct: 101 TATNSFGTIVSREAKLQF 118
Score = 40.7 bits (91), Expect = 0.081
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCCIAKNC 161
G V ECK P PV +W K LK + ++ +L GSY CIA N
Sbjct: 423 GEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNH 482
Query: 162 MGQASSSAELTVED 175
G ASS+ L V+D
Sbjct: 483 FGTASSTGNLVVKD 496
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 62.1 bits (144), Expect = 3e-08
Identities = 76/296 (25%), Positives = 121/296 (40%), Gaps = 51/296 (17%)
Query: 101 MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLTGTNSL-------- 151
+E + A++ E + +F C V +P P +SW ++ +K D Y + L
Sbjct: 34 LETVDALVEE--VATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVED 91
Query: 152 ---GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKI 208
G YCC A N +G A S L + K ++ K + GLK+V
Sbjct: 92 SDDGIYCCTANNGVGGAVESC--------GALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 209 DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
P+PS+ W + D P+ E+SR + E G L I ++ D +++C
Sbjct: 140 -----LPCTTMGNPKPSVSWIKGDSPLRENSR--IAVLESGS--LRIHNVQKEDAGQYRC 190
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPR----FLENLQAILSDE----GAVNLECKVIGVP 320
VA N G + + +KL + + + F L+A S V L C G+P
Sbjct: 191 VAKNSLGTAYSKV-VKLEVEEESEPEQDTKVFARILRAPESHNVTFGSFVTLHCTATGIP 249
Query: 321 QPVLKWYKDGEELKPGDIHRIISGQ--DGTCSL-----GTYTCEASNCMGVAASSA 369
P + W ++G + G I + + D L G YTC A+N G S+A
Sbjct: 250 VPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTA 305
Score = 47.2 bits (107), Expect = 0.001
Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 25/188 (13%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
+AP L++V+A ++E F V P+P + W R ++ + + E G
Sbjct: 26 KAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTR-NKILIKLFDTRYSIRENGQ-L 83
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSC-----FLKLIIPRHYKKPRFLENLQAILSDE 307
L I ++E D + C A N G +V SC +K I R + +E L+A+
Sbjct: 84 LTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAV---- 139
Query: 308 GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEAS 359
L C +G P+P + W K L+ RI + G+ + G Y C A
Sbjct: 140 ----LPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGSLRIHNVQKEDAGQYRCVAK 193
Query: 360 NCMGVAAS 367
N +G A S
Sbjct: 194 NSLGTAYS 201
Score = 35.1 bits (77), Expect = 4.0
Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 13/106 (12%)
Query: 97 KPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
KP+ V EGL + C +G P P +SW K L+ + + SL
Sbjct: 120 KPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHN 179
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSK 191
G Y C+AKN +G A S ++ +++ + E+ ++F++
Sbjct: 180 VQKEDAGQYRCVAKNSLGTAYS--KVVKLEVEEESEPEQDTKVFAR 223
>EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform A
protein.
Length = 1896
Score = 61.7 bits (143), Expect = 4e-08
Identities = 78/282 (27%), Positives = 114/282 (40%), Gaps = 38/282 (13%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-------PGDVYQ----LTGT--NSLGSYCCIAKNCMG 163
+C V+G P PV+ W K GQ+L P D + LT G Y C A+N G
Sbjct: 32 KCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAG 91
Query: 164 QASSSAELTV-----EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+A ++A +TV D + Q E S AP F+ G +S T +
Sbjct: 92 EAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRA 151
Query: 219 AIPPEPSLLWYRDDQPVDE---SSRCHL--GKEERG---VFFLDIQALEFLDQAEWKCVA 270
PEP+L W +D +DE SS L G+ E G L I A D + C A
Sbjct: 152 GGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHA 211
Query: 271 FNDFGQSVTSCFLKLIIPRHY------KKPR-FLENL----QAILSDEGA-VNLECKVIG 318
N G + L++ P + P +E L + +EG C V+G
Sbjct: 212 RNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMG 271
Query: 319 VPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCEASN 360
P+P ++W+ +G L P + +DG L C+A +
Sbjct: 272 KPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKD 313
Score = 52.8 bits (121), Expect = 2e-05
Identities = 71/281 (25%), Positives = 109/281 (38%), Gaps = 49/281 (17%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQEL-----------KPGDVYQLTGTN-----------SL 151
V C+ G P P L W KDG L +PG G +
Sbjct: 145 VVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDS 204
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK-FVHGLKSVEAKI-- 208
G Y C A+N G A + A L Q+++ + ++AP V LK
Sbjct: 205 GVYVCHARNAHGHAQAGALL-------QVHQPPESPPADPDEAPAPVVEPLKCAPKTFWV 257
Query: 209 --DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+ +F V PEP + W+ + +P+ R + ++ G F L + + D+ +
Sbjct: 258 NEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLY 317
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDE-GAVNLECKVIGVPQPVLK 325
C A N GQ++++ L + PR RF LQ + E G LECKV P
Sbjct: 318 VCAARNSAGQTLSAVQLHVKEPR----LRFTRPLQDVEGREHGIAVLECKVPNSRIPT-A 372
Query: 326 WYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCE 357
W+++ + L P G + R+I + G Y CE
Sbjct: 373 WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE 413
Score = 38.3 bits (85), Expect = 0.43
Identities = 62/220 (28%), Positives = 91/220 (41%), Gaps = 18/220 (8%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
F C V+G P P + W +G+ L P D +L + G + C QA L V
Sbjct: 265 FRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMYRDRDGGFVLKVLYC--QAKDRG-LYVCA 320
Query: 176 IQNQLNEE-EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+N + +QL K +F L+ VE + KV P+ W+R+DQ
Sbjct: 321 ARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPT-AWFREDQR 379
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK-LIIPRHYKK 293
+ R + EE V L I L+ D + C ++V + +K I+ R +K
Sbjct: 380 L-LPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC-EMRGRVRTVANVTVKGPILKRLPRK 437
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
LE A+L E LE V G +W +DGEEL
Sbjct: 438 LDVLEGENAVLLVE---TLEAGVEG------RWSRDGEEL 468
Score = 38.3 bits (85), Expect = 0.43
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
WY+D Q V+ES + + R L + + D E++C + V++ F +
Sbjct: 749 WYKDGQKVEESELLVVKMDGRK-HRLILPEAKVQDSGEFECRT-----EGVSAFFGVTVQ 802
Query: 288 --PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD 337
P H PR + AI S+ V L C+V PV +WYKDG+E++ D
Sbjct: 803 DPPVHIVDPREHVFVHAITSE--CVMLACEVDREDAPV-RWYKDGQEVEESD 851
Score = 36.7 bits (81), Expect = 1.3
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELK-------PGD--IHRIIS 343
P FL + + GA L+C V+G P PV+ W K G++L P D H ++
Sbjct: 12 PCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLL 71
Query: 344 GQDGTCSLGTYTCEASNCMGVAASSASL 371
G Y C A N G A ++A++
Sbjct: 72 TAALPTDAGVYVCRARNAAGEAYAAAAV 99
Score = 34.3 bits (75), Expect = 7.0
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 13/119 (10%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND---FGQSV 278
P + W +D + V ES L KE+ V L + A++ D E+ C ++ F +V
Sbjct: 925 PWAEVRWTKDGEEVVESPALLLQKEDT-VRRLVLPAVQLEDSGEYLCEIDDESASFTVTV 983
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD 337
T +++I PR + + I V L C++ PV +WYKDG E++ +
Sbjct: 984 TEPPVRIIYPR--------DEVTLIAVTLECVVLMCELSREDAPV-RWYKDGLEVEESE 1033
>EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform C
protein.
Length = 1544
Score = 61.7 bits (143), Expect = 4e-08
Identities = 78/282 (27%), Positives = 114/282 (40%), Gaps = 38/282 (13%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-------PGDVYQ----LTGT--NSLGSYCCIAKNCMG 163
+C V+G P PV+ W K GQ+L P D + LT G Y C A+N G
Sbjct: 32 KCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAG 91
Query: 164 QASSSAELTV-----EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+A ++A +TV D + Q E S AP F+ G +S T +
Sbjct: 92 EAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRA 151
Query: 219 AIPPEPSLLWYRDDQPVDE---SSRCHL--GKEERG---VFFLDIQALEFLDQAEWKCVA 270
PEP+L W +D +DE SS L G+ E G L I A D + C A
Sbjct: 152 GGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHA 211
Query: 271 FNDFGQSVTSCFLKLIIPRHY------KKPR-FLENL----QAILSDEGA-VNLECKVIG 318
N G + L++ P + P +E L + +EG C V+G
Sbjct: 212 RNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMG 271
Query: 319 VPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCEASN 360
P+P ++W+ +G L P + +DG L C+A +
Sbjct: 272 KPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKD 313
Score = 52.8 bits (121), Expect = 2e-05
Identities = 71/281 (25%), Positives = 109/281 (38%), Gaps = 49/281 (17%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQEL-----------KPGDVYQLTGTN-----------SL 151
V C+ G P P L W KDG L +PG G +
Sbjct: 145 VVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDS 204
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK-FVHGLKSVEAKI-- 208
G Y C A+N G A + A L Q+++ + ++AP V LK
Sbjct: 205 GVYVCHARNAHGHAQAGALL-------QVHQPPESPPADPDEAPAPVVEPLKCAPKTFWV 257
Query: 209 --DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+ +F V PEP + W+ + +P+ R + ++ G F L + + D+ +
Sbjct: 258 NEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLY 317
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDE-GAVNLECKVIGVPQPVLK 325
C A N GQ++++ L + PR RF LQ + E G LECKV P
Sbjct: 318 VCAARNSAGQTLSAVQLHVKEPR----LRFTRPLQDVEGREHGIAVLECKVPNSRIPT-A 372
Query: 326 WYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCE 357
W+++ + L P G + R+I + G Y CE
Sbjct: 373 WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE 413
Score = 38.3 bits (85), Expect = 0.43
Identities = 62/220 (28%), Positives = 91/220 (41%), Gaps = 18/220 (8%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
F C V+G P P + W +G+ L P D +L + G + C QA L V
Sbjct: 265 FRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMYRDRDGGFVLKVLYC--QAKDRG-LYVCA 320
Query: 176 IQNQLNEE-EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+N + +QL K +F L+ VE + KV P+ W+R+DQ
Sbjct: 321 ARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPT-AWFREDQR 379
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK-LIIPRHYKK 293
+ R + EE V L I L+ D + C ++V + +K I+ R +K
Sbjct: 380 L-LPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC-EMRGRVRTVANVTVKGPILKRLPRK 437
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
LE A+L E LE V G +W +DGEEL
Sbjct: 438 LDVLEGENAVLLVE---TLEAGVEG------RWSRDGEEL 468
Score = 38.3 bits (85), Expect = 0.43
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
WY+D Q V+ES + + R L + + D E++C + V++ F +
Sbjct: 750 WYKDGQKVEESELLVVKMDGRK-HRLILPEAKVQDSGEFECRT-----EGVSAFFGVTVQ 803
Query: 288 --PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD 337
P H PR + AI S+ V L C+V PV +WYKDG+E++ D
Sbjct: 804 DPPVHIVDPREHVFVHAITSE--CVMLACEVDREDAPV-RWYKDGQEVEESD 852
Score = 36.7 bits (81), Expect = 1.3
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELK-------PGD--IHRIIS 343
P FL + + GA L+C V+G P PV+ W K G++L P D H ++
Sbjct: 12 PCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLL 71
Query: 344 GQDGTCSLGTYTCEASNCMGVAASSASL 371
G Y C A N G A ++A++
Sbjct: 72 TAALPTDAGVYVCRARNAAGEAYAAAAV 99
Score = 34.3 bits (75), Expect = 7.0
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 13/119 (10%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND---FGQSV 278
P + W +D + V ES L KE+ V L + A++ D E+ C ++ F +V
Sbjct: 926 PWAEVRWTKDGEEVVESPALLLQKEDT-VRRLVLPAVQLEDSGEYLCEIDDESASFTVTV 984
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD 337
T +++I PR + + I V L C++ PV +WYKDG E++ +
Sbjct: 985 TEPPVRIIYPR--------DEVTLIAVTLECVVLMCELSREDAPV-RWYKDGLEVEESE 1034
>BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein.
Length = 1044
Score = 61.7 bits (143), Expect = 4e-08
Identities = 78/282 (27%), Positives = 114/282 (40%), Gaps = 38/282 (13%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-------PGDVYQ----LTGT--NSLGSYCCIAKNCMG 163
+C V+G P PV+ W K GQ+L P D + LT G Y C A+N G
Sbjct: 51 KCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAG 110
Query: 164 QASSSAELTV-----EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
+A ++A +TV D + Q E S AP F+ G +S T +
Sbjct: 111 EAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRA 170
Query: 219 AIPPEPSLLWYRDDQPVDE---SSRCHL--GKEERG---VFFLDIQALEFLDQAEWKCVA 270
PEP+L W +D +DE SS L G+ E G L I A D + C A
Sbjct: 171 GGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHA 230
Query: 271 FNDFGQSVTSCFLKLIIPRHY------KKPR-FLENL----QAILSDEGA-VNLECKVIG 318
N G + L++ P + P +E L + +EG C V+G
Sbjct: 231 RNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMG 290
Query: 319 VPQPVLKWYKDGEELKPGDIHRIISGQDGTCSLGTYTCEASN 360
P+P ++W+ +G L P + +DG L C+A +
Sbjct: 291 KPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKD 332
Score = 52.8 bits (121), Expect = 2e-05
Identities = 71/281 (25%), Positives = 109/281 (38%), Gaps = 49/281 (17%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQEL-----------KPGDVYQLTGTN-----------SL 151
V C+ G P P L W KDG L +PG G +
Sbjct: 164 VVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDS 223
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK-FVHGLKSVEAKI-- 208
G Y C A+N G A + A L Q+++ + ++AP V LK
Sbjct: 224 GVYVCHARNAHGHAQAGALL-------QVHQPPESPPADPDEAPAPVVEPLKCAPKTFWV 276
Query: 209 --DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+ +F V PEP + W+ + +P+ R + ++ G F L + + D+ +
Sbjct: 277 NEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLY 336
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDE-GAVNLECKVIGVPQPVLK 325
C A N GQ++++ L + PR RF LQ + E G LECKV P
Sbjct: 337 VCAARNSAGQTLSAVQLHVKEPR----LRFTRPLQDVEGREHGIAVLECKVPNSRIPT-A 391
Query: 326 WYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCE 357
W+++ + L P G + R+I + G Y CE
Sbjct: 392 WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE 432
Score = 38.3 bits (85), Expect = 0.43
Identities = 62/220 (28%), Positives = 91/220 (41%), Gaps = 18/220 (8%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
F C V+G P P + W +G+ L P D +L + G + C QA L V
Sbjct: 284 FRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMYRDRDGGFVLKVLYC--QAKDRG-LYVCA 339
Query: 176 IQNQLNEE-EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+N + +QL K +F L+ VE + KV P+ W+R+DQ
Sbjct: 340 ARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPT-AWFREDQR 398
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK-LIIPRHYKK 293
+ R + EE V L I L+ D + C ++V + +K I+ R +K
Sbjct: 399 L-LPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC-EMRGRVRTVANVTVKGPILKRLPRK 456
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
LE A+L E LE V G +W +DGEEL
Sbjct: 457 LDVLEGENAVLLVE---TLEAGVEG------RWSRDGEEL 487
Score = 38.3 bits (85), Expect = 0.43
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
WY+D Q V+ES + + R L + + D E++C + V++ F +
Sbjct: 768 WYKDGQKVEESELLVVKMDGRK-HRLILPEAKVQDSGEFECRT-----EGVSAFFGVTVQ 821
Query: 288 --PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD 337
P H PR + AI S+ V L C+V PV +WYKDG+E++ D
Sbjct: 822 DPPVHIVDPREHVFVHAITSE--CVMLACEVDREDAPV-RWYKDGQEVEESD 870
Score = 36.7 bits (81), Expect = 1.3
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELK-------PGD--IHRIIS 343
P FL + + GA L+C V+G P PV+ W K G++L P D H ++
Sbjct: 31 PCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLL 90
Query: 344 GQDGTCSLGTYTCEASNCMGVAASSASL 371
G Y C A N G A ++A++
Sbjct: 91 TAALPTDAGVYVCRARNAAGEAYAAAAV 118
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 61.7 bits (143), Expect = 4e-08
Identities = 64/238 (26%), Positives = 96/238 (40%), Gaps = 34/238 (14%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL-------KPGDVYQLTGTN--SLGSYCCIA 158
LT + C G P P ++W KDGQ L + V ++ G Y C+A
Sbjct: 418 LTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVENVQVRDAGLYTCLA 477
Query: 159 KNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKV 218
++ G S + V+ N + + P+FV GL + ++ V
Sbjct: 478 ESPAGAIEKSFRVRVQAPPNIVGP----------RGPRFVVGLAPGQLVLE------CSV 521
Query: 219 AIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSV 278
P P + W+RD + E + H ERG F L +QAL D ++ C A N G
Sbjct: 522 EAEPAPKITWHRDGIVLQEDA--HTQFPERGRF-LQLQALSTADSGDYSCTARNAAGS-- 576
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAI-LSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
TS ++ I + P A+ +S L C+ GVP P++ W KD L P
Sbjct: 577 TSVAFRVEI---HTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDP 631
Score = 60.5 bits (140), Expect = 9e-08
Identities = 69/277 (24%), Positives = 112/277 (40%), Gaps = 25/277 (9%)
Query: 98 PRFMEN-LQAVLTEEGLVSF-ECKVVGFPTPVLSWFKDGQELKPGD-VYQLTGTNSLGSY 154
P +EN L + T EG +F CK G P P ++W KDGQ + + + + + L
Sbjct: 934 PPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL--- 990
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
+ KN GQ + + T E+ + L + P F ++ +
Sbjct: 991 --LVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV---LPVFTTLPGDRSLRLGDRLWL 1045
Query: 215 TIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF 274
P P + W +D+PV E E+ G L A+ D + C A N
Sbjct: 1046 RCAARGSPTPRIGWTVNDRPVTEGV-----SEQDGGSTLQRAAVSREDSGTYVCWAENRV 1100
Query: 275 GQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELK 334
G++ F+ + + F ++ + G++ L+C V G P P + W KDG L+
Sbjct: 1101 GRTQAVSFVHVKEAPVLQGEAFSYLVEPV---GGSIQLDCVVRGDPVPDIHWIKDGLPLR 1157
Query: 335 PGDI-HRIISG-----QDGTCSLGTYTCEASNCMGVA 365
+ H++ +G + G Y C A N MGVA
Sbjct: 1158 GSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVA 1194
Score = 52.4 bits (120), Expect = 2e-05
Identities = 67/291 (23%), Positives = 115/291 (39%), Gaps = 23/291 (7%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP + P+ E + V +++ C V G P P ++W KD ++ V+ G S
Sbjct: 35 VPPTFENPK-TETVSQVAGSPLVLT--CDVSGVPAPTVTWLKDRMPVESSAVH---GVVS 88
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
G +++ QA + + +N E K + + AP+ + E + E
Sbjct: 89 RGGRLQLSRLQPAQAGTYTCVA----ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLE 144
Query: 211 --PFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKC 268
R + P P + W +D P+ + HL G L ++ L D + C
Sbjct: 145 GQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDG-GSLVLKGLWASDAGAYTC 203
Query: 269 VAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWY 327
VA N G+ + +++P K+ + ++S G V + C V G P + W
Sbjct: 204 VAHNPAGEDARLHTVNVLVPPTIKQG--ADGSGTLVSRPGELVTMVCPVRGSPPIHVSWL 261
Query: 328 KDG-------EELKPGDIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
KDG L G H + + G +TC A++ GVA + +L
Sbjct: 262 KDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTL 312
Score = 50.4 bits (115), Expect = 1e-04
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNL 312
L+IQ + D+ + C N G++V + L + +P ++ P+ E + + + L
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPK-TETVSQVAGSP--LVL 57
Query: 313 ECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGV 364
C V GVP P + W KD ++ +H ++S + G L GTYTC A N
Sbjct: 58 TCDVSGVPAPTVTWLKDRMPVESSAVHGVVS-RGGRLQLSRLQPAQAGTYTCVAENTQAE 116
Query: 365 A 365
A
Sbjct: 117 A 117
Score = 49.6 bits (113), Expect = 2e-04
Identities = 72/281 (25%), Positives = 105/281 (37%), Gaps = 54/281 (19%)
Query: 104 LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GS 153
++AV EE L+ C+ G P P ++W K+G + G Q+ L G+
Sbjct: 854 VRAVAEEEVLLP--CEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGN 911
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
Y CIAKN G A L V+ P +GL +
Sbjct: 912 YLCIAKNSAGSAMGKTRLVVQ------------------VPPVIENGLPDLSTTEGSHAF 953
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
K PEP++ W +D QPV + + G L ++ LE D + C A N
Sbjct: 954 LPCKARGSPEPNITWDKDGQPV-SGAEGKFTIQPSGE--LLVKNLEGQDAGTYTCTAENA 1010
Query: 274 FGQSVTSCFLK-LIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEE 332
G++ L L++P P + L D + L C G P P + W +
Sbjct: 1011 VGRARRRVHLTILVLPVFTTLP---GDRSLRLGDR--LWLRCAARGSPTPRIGWTVNDRP 1065
Query: 333 LKPGDIHRIISGQDGTCSL----------GTYTCEASNCMG 363
+ G +S QDG +L GTY C A N +G
Sbjct: 1066 VTEG-----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 1101
Score = 47.6 bits (108), Expect = 7e-04
Identities = 61/267 (22%), Positives = 99/267 (37%), Gaps = 20/267 (7%)
Query: 113 LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
L C+ G P P++ W+KDGQ+L D G L + G S+
Sbjct: 677 LALLPCEASGSPKPLVVWWKDGQKL---DFRLQQGAYRLLPSNALLLTAPGPQDSAQFEC 733
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDD 232
V + N++ E +L + + P + P T P P++ W +
Sbjct: 734 V--VSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAG 791
Query: 233 QPVDESSRCHLGKEERGVFFLDI-QALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHY 291
+ G L+I QAL + + C A N G + FL +
Sbjct: 792 AQLGARGS---GYRVSPSGALEIGQALP-IHAGRYTCSARNSAGVAHKHVFLT-VQASPV 846
Query: 292 KKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG------Q 345
KP L ++ +++E V L C+ G+P+P + W K+G + G +++ G
Sbjct: 847 VKP--LPSVVRAVAEE-EVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAH 903
Query: 346 DGTCSLGTYTCEASNCMGVAASSASLL 372
G Y C A N G A L+
Sbjct: 904 ASPEDAGNYLCIAKNSAGSAMGKTRLV 930
Score = 47.6 bits (108), Expect = 7e-04
Identities = 62/265 (23%), Positives = 104/265 (39%), Gaps = 30/265 (11%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQ 177
C G PTP + W + + + G V + G ++L +++ G AE
Sbjct: 1047 CAARGSPTPRIGWTVNDRPVTEG-VSEQDGGSTL-QRAAVSREDSGTYVCWAE------- 1097
Query: 178 NQLNEEEKLQLFSKNQAPKFV-HGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVD 236
N++ + + +AP + + + V P P + W +D P+
Sbjct: 1098 NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR 1157
Query: 237 ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRF 296
S H + + G L I E D ++C+A N+ G + K++I P F
Sbjct: 1158 GSHLRH--QLQNGS--LTIHRTERDDAGRYQCLAENEMGVAK-----KVVILVLQSAPVF 1208
Query: 297 LENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG-------- 347
Q + G V L C+ G P P ++W + G+ L+ R+ + DG
Sbjct: 1209 QVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS--RRLRTLPDGSLWLENVE 1266
Query: 348 TCSLGTYTCEASNCMGVAASSASLL 372
T GTY C A N +G A + A L+
Sbjct: 1267 TGDAGTYDCVAHNLLGSATARAFLV 1291
Score = 40.3 bits (90), Expect = 0.11
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNL 312
L ++A+ D + CVA ++ G++ L ++ P H + + + L+ + L
Sbjct: 369 LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSG--QPTELSLTPGAPMEL 426
Query: 313 ECKVIGVPQPVLKWYKDGEEL 333
C G PQP + W+KDG+ L
Sbjct: 427 LCDAQGTPQPNITWHKDGQAL 447
Score = 39.9 bits (89), Expect = 0.14
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 10/70 (14%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELK---------PGDVY-QLTGTNSLGSYCCIAKNCMG 163
V+ C+ G PTP + W + GQ L+ G ++ + T G+Y C+A N +G
Sbjct: 1223 VALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLG 1282
Query: 164 QASSSAELTV 173
A++ A L V
Sbjct: 1283 SATARAFLVV 1292
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 61.7 bits (143), Expect = 4e-08
Identities = 78/296 (26%), Positives = 130/296 (43%), Gaps = 37/296 (12%)
Query: 97 KPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F+ + V+ + V+F C+V G P P L W K+ EL G Y++ +SL
Sbjct: 257 RPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGR-YEIRSDHSLWIGH 315
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G+Y C+A+N +G+A +S L+V + QL + + Q+ + ++ F E
Sbjct: 316 VSAEDEGTYTCVAENSVGRAEASGSLSVH-VPPQLVTQPQDQMAAPGESVAF-----QCE 369
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
K + P + E S + Q + + R + RG L+I A++ D
Sbjct: 370 TKGNPP----PAIFWQKEGSQVLLFPSQSLQPTGRFSVSP--RGQ--LNITAVQRGDAGY 421
Query: 266 WKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLEN-LQAILSDEGAVNLECKVIGVPQPV 323
+ C A + G + L++ P L+ L +V L C+V G PQP
Sbjct: 422 YMCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPS 481
Query: 324 LKWYKDGEELKPGDIHRIISGQDGT--------CSLGTYTCEASNCMGVAASSASL 371
++W KDG+ L+ GD + + +GT +G Y+C A + G A S L
Sbjct: 482 VRWKKDGQWLQ-GDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWL 536
Score = 52.8 bits (121), Expect = 2e-05
Identities = 57/223 (25%), Positives = 90/223 (40%), Gaps = 38/223 (17%)
Query: 122 GFPTPVLSWFKDGQELKP--------GDVYQLTGT--NSLGSYCCIAKNCMGQASSSAEL 171
G P P +SW KDG LK G ++ T + G Y C+A N G+ S+A
Sbjct: 192 GHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAA- 250
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD 231
E + L + P F+ + D P F +V P P L W ++
Sbjct: 251 ------------EVMVL----ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKE 294
Query: 232 DQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHY 291
D + E R L I + D+ + CVA N G++ S L + +P
Sbjct: 295 DGELPTGR-----YEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVP--- 346
Query: 292 KKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
P+ + Q ++ G +V +C+ G P P + W K+G ++
Sbjct: 347 --PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQV 387
Score = 38.3 bits (85), Expect = 0.43
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 11/69 (15%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS-----------LGSYCCIAKNCMGQAS 166
C+V G P P + W KDGQ L+ D+ T N +G Y C+AK+ G+A+
Sbjct: 472 CRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEAT 531
Query: 167 SSAELTVED 175
S L + +
Sbjct: 532 WSGWLKMRE 540
Score = 37.1 bits (82), Expect = 1.00
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 17/190 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ---PVDESSRCHLGKEERGVF 251
P+ V + EP + P P++ WY++ V E R H G
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 252 FLD--IQALEFL-DQAEWKCVAFNDFGQSVT-SCFLKLIIPRHYKKPRFLENLQAILSDE 307
F + D+ + CVA N G + + + L++ + R + + A+ E
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAV--GE 181
Query: 308 GAVNLEC-KVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCS------LGTYTCEASN 360
AV LEC G P+P + W KDG LK + I G S G Y C ASN
Sbjct: 182 PAV-LECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASN 240
Query: 361 CMGVAASSAS 370
G S+A+
Sbjct: 241 MAGERESAAA 250
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 61.3 bits (142), Expect = 5e-08
Identities = 78/296 (26%), Positives = 130/296 (43%), Gaps = 37/296 (12%)
Query: 97 KPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F+ + V+ + V+F C+V G P P L W K+ EL G Y++ +SL
Sbjct: 257 RPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGR-YEIRSDHSLWIGH 315
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G+Y C+A+N +G+A +S L+V + QL + + Q+ + ++ F E
Sbjct: 316 VSAEDEGTYTCVAENSVGRAEASGSLSVH-VPPQLVTQPQDQMAAPGESVAF-----QCE 369
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
K + P + E S + Q + + R + RG L+I A++ D
Sbjct: 370 TKGNPP----PAIFWQKEGSQVLLFPSQSLQPTGRFSVSP--RGQ--LNITAVQRGDAGY 421
Query: 266 WKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLEN-LQAILSDEGAVNLECKVIGVPQPV 323
+ C A + G + L++ P L+ L +V L C+V G PQP
Sbjct: 422 YVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPS 481
Query: 324 LKWYKDGEELKPGDIHRIISGQDGT--------CSLGTYTCEASNCMGVAASSASL 371
++W KDG+ L+ GD + + +GT +G Y+C A + G A S L
Sbjct: 482 VRWKKDGQWLQ-GDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWL 536
Score = 52.8 bits (121), Expect = 2e-05
Identities = 57/223 (25%), Positives = 90/223 (40%), Gaps = 38/223 (17%)
Query: 122 GFPTPVLSWFKDGQELKP--------GDVYQLTGT--NSLGSYCCIAKNCMGQASSSAEL 171
G P P +SW KDG LK G ++ T + G Y C+A N G+ S+A
Sbjct: 192 GHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAA- 250
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD 231
E + L + P F+ + D P F +V P P L W ++
Sbjct: 251 ------------EVMVL----ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKE 294
Query: 232 DQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHY 291
D + E R L I + D+ + CVA N G++ S L + +P
Sbjct: 295 DGELPTGR-----YEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVP--- 346
Query: 292 KKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
P+ + Q ++ G +V +C+ G P P + W K+G ++
Sbjct: 347 --PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQV 387
Score = 38.3 bits (85), Expect = 0.43
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 11/69 (15%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS-----------LGSYCCIAKNCMGQAS 166
C+V G P P + W KDGQ L+ D+ T N +G Y C+AK+ G+A+
Sbjct: 472 CRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEAT 531
Query: 167 SSAELTVED 175
S L + +
Sbjct: 532 WSGWLKMRE 540
Score = 37.1 bits (82), Expect = 1.00
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 17/190 (8%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ---PVDESSRCHLGKEERGVF 251
P+ V + EP + P P++ WY++ V E R H G
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 252 FLD--IQALEFL-DQAEWKCVAFNDFGQSVT-SCFLKLIIPRHYKKPRFLENLQAILSDE 307
F + D+ + CVA N G + + + L++ + R + + A+ E
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAV--GE 181
Query: 308 GAVNLEC-KVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCS------LGTYTCEASN 360
AV LEC G P+P + W KDG LK + I G S G Y C ASN
Sbjct: 182 PAV-LECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASN 240
Query: 361 CMGVAASSAS 370
G S+A+
Sbjct: 241 MAGERESAAA 250
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 60.1 bits (139), Expect = 1e-07
Identities = 63/266 (23%), Positives = 106/266 (39%), Gaps = 25/266 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V EC +G P P ++W K + P +L + ++ N + E
Sbjct: 318 VKMECFALGNPVPTITWMKVNGYI-PSKA-RLRKSQAVLEI----PNVQLDDAGIYECRA 371
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
E+ + + + +LQ+++ P +V L + P R+ K P P+ W ++
Sbjct: 372 ENSRGKNSFRGQLQVYTY---PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV 428
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
P+ SR + GV L I + D ++C+A N +G S LK++
Sbjct: 429 PLSPQSRVEM---VNGV--LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA 483
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
L+ + D+ V +ECK G P+P + W K ++ + RI DG+ +
Sbjct: 484 LNQLKKTIIVTKDQEVV-IECKPQGSPKPTISWKKGDRAVR--ENKRIAILPDGSLRILN 540
Query: 352 ------GTYTCEASNCMGVAASSASL 371
G Y C N G A ASL
Sbjct: 541 ASKSDEGKYVCRGENVFGSAEIIASL 566
Score = 53.6 bits (123), Expect = 1e-05
Identities = 58/233 (24%), Positives = 101/233 (43%), Gaps = 29/233 (12%)
Query: 148 TNSLGSYCCIAKNCMGQASSSAELTVEDIQNQ--LNE-EEKLQLFSKNQAPKFVHGLKSV 204
T+ +GSY C+ KN + A + T ++N + E E K+++ P V K
Sbjct: 261 TSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEV----HFPFTVTAAKGT 316
Query: 205 EAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA 264
K++ F + P P++ W + + + +R ++ + V L+I ++ D
Sbjct: 317 TVKME---CFALG---NPVPTITWMKVNGYIPSKARL---RKSQAV--LEIPNVQLDDAG 365
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPV 323
++C A N G++ L++ Y P ++E L D G+ + ECK G P+P
Sbjct: 366 IYECRAENSRGKNSFRGQLQV-----YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPT 420
Query: 324 LKWYKDGEELKPGDIHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASL 371
+W K+G L P +++G G Y C A N G +SA L
Sbjct: 421 YRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 473
Score = 47.6 bits (108), Expect = 7e-04
Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 25/156 (16%)
Query: 95 YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP-GDVYQLTGT---- 148
Y P ++E L + G + +ECK G P P W K+G L P V + G
Sbjct: 387 YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIH 446
Query: 149 ----NSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV 204
+ G Y C+A+N G +SAEL + F+ NQ K + K
Sbjct: 447 NVNQSDAGMYQCLAENKYGAIYASAELKI---------LASAPTFALNQLKKTIIVTKDQ 497
Query: 205 EAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
E I+ K P+P++ W + D+ V E+ R
Sbjct: 498 EVVIE------CKPQGSPKPTISWKKGDRAVRENKR 527
Score = 37.9 bits (84), Expect = 0.57
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 305 SDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHR--------IISGQDGTCSLGTYTC 356
SDE V L C+V G P P +W ++G E+ +R IIS G Y C
Sbjct: 114 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQC 173
Query: 357 EASNCMGVAASSASLLGF 374
A+N +G S + L F
Sbjct: 174 LATNTVGSILSREATLQF 191
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 60.1 bits (139), Expect = 1e-07
Identities = 63/266 (23%), Positives = 106/266 (39%), Gaps = 25/266 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V EC +G P P ++W K + P +L + ++ N + E
Sbjct: 24 VKMECFALGNPVPTITWMKVNGYI-PSKA-RLRKSQAVLEI----PNVQLDDAGIYECRA 77
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
E+ + + + +LQ+++ P +V L + P R+ K P P+ W ++
Sbjct: 78 ENSRGKNSFRGQLQVYTY---PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV 134
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
P+ SR + GV L I + D ++C+A N +G S LK++
Sbjct: 135 PLSPQSRVEM---VNGV--LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA 189
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
L+ + D+ V +ECK G P+P + W K ++ + RI DG+ +
Sbjct: 190 LNQLKKTIIVTKDQEVV-IECKPQGSPKPTISWKKGDRAVR--ENKRIAILPDGSLRILN 246
Query: 352 ------GTYTCEASNCMGVAASSASL 371
G Y C N G A ASL
Sbjct: 247 ASKSDEGKYVCRGENVFGSAEIIASL 272
Score = 47.6 bits (108), Expect = 7e-04
Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 25/156 (16%)
Query: 95 YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP-GDVYQLTGT---- 148
Y P ++E L + G + +ECK G P P W K+G L P V + G
Sbjct: 93 YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIH 152
Query: 149 ----NSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV 204
+ G Y C+A+N G +SAEL + F+ NQ K + K
Sbjct: 153 NVNQSDAGMYQCLAENKYGAIYASAELKI---------LASAPTFALNQLKKTIIVTKDQ 203
Query: 205 EAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
E I+ K P+P++ W + D+ V E+ R
Sbjct: 204 EVVIE------CKPQGSPKPTISWKKGDRAVRENKR 233
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 60.1 bits (139), Expect = 1e-07
Identities = 63/266 (23%), Positives = 106/266 (39%), Gaps = 25/266 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V EC +G P P ++W K + P +L + ++ N + E
Sbjct: 244 VKMECFALGNPVPTITWMKVNGYI-PSKA-RLRKSQAVLEI----PNVQLDDAGIYECRA 297
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
E+ + + + +LQ+++ P +V L + P R+ K P P+ W ++
Sbjct: 298 ENSRGKNSFRGQLQVYTY---PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV 354
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
P+ SR + GV L I + D ++C+A N +G S LK++
Sbjct: 355 PLSPQSRVEM---VNGV--LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA 409
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
L+ + D+ V +ECK G P+P + W K ++ + RI DG+ +
Sbjct: 410 LNQLKKTIIVTKDQEVV-IECKPQGSPKPTISWKKGDRAVR--ENKRIAILPDGSLRILN 466
Query: 352 ------GTYTCEASNCMGVAASSASL 371
G Y C N G A ASL
Sbjct: 467 ASKSDEGKYVCRGENVFGSAEIIASL 492
Score = 53.6 bits (123), Expect = 1e-05
Identities = 58/233 (24%), Positives = 101/233 (43%), Gaps = 29/233 (12%)
Query: 148 TNSLGSYCCIAKNCMGQASSSAELTVEDIQNQ--LNE-EEKLQLFSKNQAPKFVHGLKSV 204
T+ +GSY C+ KN + A + T ++N + E E K+++ P V K
Sbjct: 187 TSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEV----HFPFTVTAAKGT 242
Query: 205 EAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA 264
K++ F + P P++ W + + + +R ++ + V L+I ++ D
Sbjct: 243 TVKME---CFALG---NPVPTITWMKVNGYIPSKARL---RKSQAV--LEIPNVQLDDAG 291
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPV 323
++C A N G++ L++ Y P ++E L D G+ + ECK G P+P
Sbjct: 292 IYECRAENSRGKNSFRGQLQV-----YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPT 346
Query: 324 LKWYKDGEELKPGDIHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASL 371
+W K+G L P +++G G Y C A N G +SA L
Sbjct: 347 YRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 399
Score = 47.6 bits (108), Expect = 7e-04
Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 25/156 (16%)
Query: 95 YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP-GDVYQLTGT---- 148
Y P ++E L + G + +ECK G P P W K+G L P V + G
Sbjct: 313 YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIH 372
Query: 149 ----NSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV 204
+ G Y C+A+N G +SAEL + F+ NQ K + K
Sbjct: 373 NVNQSDAGMYQCLAENKYGAIYASAELKI---------LASAPTFALNQLKKTIIVTKDQ 423
Query: 205 EAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
E I+ K P+P++ W + D+ V E+ R
Sbjct: 424 EVVIE------CKPQGSPKPTISWKKGDRAVRENKR 453
Score = 37.9 bits (84), Expect = 0.57
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 305 SDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHR--------IISGQDGTCSLGTYTC 356
SDE V L C+V G P P +W ++G E+ +R IIS G Y C
Sbjct: 40 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQC 99
Query: 357 EASNCMGVAASSASLLGF 374
A+N +G S + L F
Sbjct: 100 LATNTVGSILSREATLQF 117
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 60.1 bits (139), Expect = 1e-07
Identities = 63/266 (23%), Positives = 106/266 (39%), Gaps = 25/266 (9%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V EC +G P P ++W K + P +L + ++ N + E
Sbjct: 318 VKMECFALGNPVPTITWMKVNGYI-PSKA-RLRKSQAVLEI----PNVQLDDAGIYECRA 371
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
E+ + + + +LQ+++ P +V L + P R+ K P P+ W ++
Sbjct: 372 ENSRGKNSFRGQLQVYTY---PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV 428
Query: 234 PVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK 293
P+ SR + GV L I + D ++C+A N +G S LK++
Sbjct: 429 PLSPQSRVEM---VNGV--LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFA 483
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL-- 351
L+ + D+ V +ECK G P+P + W K ++ + RI DG+ +
Sbjct: 484 LNQLKKTIIVTKDQEVV-IECKPQGSPKPTISWKKGDRAVR--ENKRIAILPDGSLRILN 540
Query: 352 ------GTYTCEASNCMGVAASSASL 371
G Y C N G A ASL
Sbjct: 541 ASKSDEGKYVCRGENVFGSAEIIASL 566
Score = 53.6 bits (123), Expect = 1e-05
Identities = 58/233 (24%), Positives = 101/233 (43%), Gaps = 29/233 (12%)
Query: 148 TNSLGSYCCIAKNCMGQASSSAELTVEDIQNQ--LNE-EEKLQLFSKNQAPKFVHGLKSV 204
T+ +GSY C+ KN + A + T ++N + E E K+++ P V K
Sbjct: 261 TSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEV----HFPFTVTAAKGT 316
Query: 205 EAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA 264
K++ F + P P++ W + + + +R ++ + V L+I ++ D
Sbjct: 317 TVKME---CFALG---NPVPTITWMKVNGYIPSKARL---RKSQAV--LEIPNVQLDDAG 365
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPV 323
++C A N G++ L++ Y P ++E L D G+ + ECK G P+P
Sbjct: 366 IYECRAENSRGKNSFRGQLQV-----YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPT 420
Query: 324 LKWYKDGEELKPGDIHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASL 371
+W K+G L P +++G G Y C A N G +SA L
Sbjct: 421 YRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 473
Score = 47.6 bits (108), Expect = 7e-04
Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 25/156 (16%)
Query: 95 YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKP-GDVYQLTGT---- 148
Y P ++E L + G + +ECK G P P W K+G L P V + G
Sbjct: 387 YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIH 446
Query: 149 ----NSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV 204
+ G Y C+A+N G +SAEL + F+ NQ K + K
Sbjct: 447 NVNQSDAGMYQCLAENKYGAIYASAELKI---------LASAPTFALNQLKKTIIVTKDQ 497
Query: 205 EAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
E I+ K P+P++ W + D+ V E+ R
Sbjct: 498 EVVIE------CKPQGSPKPTISWKKGDRAVRENKR 527
Score = 37.9 bits (84), Expect = 0.57
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 305 SDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHR--------IISGQDGTCSLGTYTC 356
SDE V L C+V G P P +W ++G E+ +R IIS G Y C
Sbjct: 114 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQC 173
Query: 357 EASNCMGVAASSASLLGF 374
A+N +G S + L F
Sbjct: 174 LATNTVGSILSREATLQF 191
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 59.7 bits (138), Expect = 2e-07
Identities = 75/296 (25%), Positives = 123/296 (41%), Gaps = 42/296 (14%)
Query: 99 RFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKP--GD---VYQLTGT---- 148
RF+ ++V G V +C+V+G P P + W K+ Q+L P GD V +G
Sbjct: 141 RFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQIS 200
Query: 149 ----NSLGSYCCIAKN-CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+G Y C A+N + + AE+ + L++ + Q P V ++
Sbjct: 201 RLQPGDIGIYRCSARNPASSRTGNEAEVRI------LSDPGLHRQLYFLQRPSNVVAIEG 254
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+A ++ V+ P PS W R ++ + S+ + G L I + D
Sbjct: 255 KDAVLE------CCVSGYPPPSFTWLRGEEVIQLRSKKY---SLLGGSNLLISNVTDDDS 305
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQP 322
+ CV S L +++P P FL + + + E + EC V G P P
Sbjct: 306 GMYTCVVTYKNENISASAELTVLVP-----PWFLNHPSNLYAYESMDIEFECTVSGKPVP 360
Query: 323 VLKWYKDGEELKPGDIHRIISGQD----GTCSL--GTYTCEASNCMGVAASSASLL 372
+ W K+G+ + P D +I+ G + G G Y C A N G A +SA L+
Sbjct: 361 TVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLI 416
Score = 52.8 bits (121), Expect = 2e-05
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 11/87 (12%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F+ + + E + + FEC V G P P ++W K+G + P D +Q+ G ++L
Sbjct: 331 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGV 390
Query: 152 -----GSYCCIAKNCMGQASSSAELTV 173
G Y C+A+N G A +SA+L V
Sbjct: 391 VKSDEGFYQCVAENEAGNAQTSAQLIV 417
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 59.7 bits (138), Expect = 2e-07
Identities = 75/296 (25%), Positives = 123/296 (41%), Gaps = 42/296 (14%)
Query: 99 RFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKP--GD---VYQLTGT---- 148
RF+ ++V G V +C+V+G P P + W K+ Q+L P GD V +G
Sbjct: 141 RFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQIS 200
Query: 149 ----NSLGSYCCIAKN-CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+G Y C A+N + + AE+ + L++ + Q P V ++
Sbjct: 201 RLQPGDIGIYRCSARNPASSRTGNEAEVRI------LSDPGLHRQLYFLQRPSNVVAIEG 254
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+A ++ V+ P PS W R ++ + S+ + G L I + D
Sbjct: 255 KDAVLE------CCVSGYPPPSFTWLRGEEVIQLRSKKY---SLLGGSNLLISNVTDDDS 305
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQP 322
+ CV S L +++P P FL + + + E + EC V G P P
Sbjct: 306 GMYTCVVTYKNENISASAELTVLVP-----PWFLNHPSNLYAYESMDIEFECTVSGKPVP 360
Query: 323 VLKWYKDGEELKPGDIHRIISGQD----GTCSL--GTYTCEASNCMGVAASSASLL 372
+ W K+G+ + P D +I+ G + G G Y C A N G A +SA L+
Sbjct: 361 TVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLI 416
Score = 52.8 bits (121), Expect = 2e-05
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 11/87 (12%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F+ + + E + + FEC V G P P ++W K+G + P D +Q+ G ++L
Sbjct: 331 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGV 390
Query: 152 -----GSYCCIAKNCMGQASSSAELTV 173
G Y C+A+N G A +SA+L V
Sbjct: 391 VKSDEGFYQCVAENEAGNAQTSAQLIV 417
>BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein.
Length = 347
Score = 59.7 bits (138), Expect = 2e-07
Identities = 42/168 (25%), Positives = 75/168 (44%), Gaps = 5/168 (2%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 48 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 107
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGL-KSVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 108 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 167
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
W++D PVD ++ K+ R L I++ E DQ +++CVA N G
Sbjct: 168 WFKDFLPVDPATSNGRIKQLRS-GALQIESSEESDQGKYECVATNSAG 214
Score = 40.7 bits (91), Expect = 0.081
Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 17/174 (9%)
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFL-DQAEWKCVAF 271
F + P+P + W + + V S R + + + G L IQ L D+A ++C A
Sbjct: 52 FVCQATGEPKPRITWMKKGKKVS-SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTAT 110
Query: 272 NDFGQSVTSCFLKLI----IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G+ TS L ++ +P + L+ + A L C G P P + W+
Sbjct: 111 NSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATML-CAAGGNPDPEISWF 169
Query: 328 KDGEELKP----GDIHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASLL 372
KD + P G I ++ SG G Y C A+N G S+ + L
Sbjct: 170 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
>AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 347
Score = 59.7 bits (138), Expect = 2e-07
Identities = 42/168 (25%), Positives = 75/168 (44%), Gaps = 5/168 (2%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 48 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 107
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGL-KSVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 108 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 167
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
W++D PVD ++ K+ R L I++ E DQ +++CVA N G
Sbjct: 168 WFKDFLPVDPATSNGRIKQLRS-GALQIESSEESDQGKYECVATNSAG 214
Score = 40.7 bits (91), Expect = 0.081
Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 17/174 (9%)
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFL-DQAEWKCVAF 271
F + P+P + W + + V S R + + + G L IQ L D+A ++C A
Sbjct: 52 FVCQATGEPKPRITWMKKGKKVS-SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTAT 110
Query: 272 NDFGQSVTSCFLKLI----IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G+ TS L ++ +P + L+ + A L C G P P + W+
Sbjct: 111 NSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATML-CAAGGNPDPEISWF 169
Query: 328 KDGEELKP----GDIHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASLL 372
KD + P G I ++ SG G Y C A+N G S+ + L
Sbjct: 170 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
>AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 262
Score = 59.7 bits (138), Expect = 2e-07
Identities = 42/168 (25%), Positives = 75/168 (44%), Gaps = 5/168 (2%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 48 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 107
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGL-KSVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 108 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 167
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
W++D PVD ++ K+ R L I++ E DQ +++CVA N G
Sbjct: 168 WFKDFLPVDPATSNGRIKQLRS-GALQIESSEESDQGKYECVATNSAG 214
Score = 40.7 bits (91), Expect = 0.081
Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 17/174 (9%)
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFL-DQAEWKCVAF 271
F + P+P + W + + V S R + + + G L IQ L D+A ++C A
Sbjct: 52 FVCQATGEPKPRITWMKKGKKVS-SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTAT 110
Query: 272 NDFGQSVTSCFLKLI----IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G+ TS L ++ +P + L+ + A L C G P P + W+
Sbjct: 111 NSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATML-CAAGGNPDPEISWF 169
Query: 328 KDGEELKP----GDIHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASLL 372
KD + P G I ++ SG G Y C A+N G S+ + L
Sbjct: 170 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
>AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1
protein.
Length = 1484
Score = 59.7 bits (138), Expect = 2e-07
Identities = 42/168 (25%), Positives = 75/168 (44%), Gaps = 5/168 (2%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 68 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 127
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGL-KSVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 128 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 187
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
W++D PVD ++ K+ R L I++ E DQ +++CVA N G
Sbjct: 188 WFKDFLPVDPATSNGRIKQLRS-GALQIESSEESDQGKYECVATNSAG 234
Score = 40.7 bits (91), Expect = 0.081
Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 17/174 (9%)
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFL-DQAEWKCVAF 271
F + P+P + W + + V S R + + + G L IQ L D+A ++C A
Sbjct: 72 FVCQATGEPKPRITWMKKGKKVS-SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTAT 130
Query: 272 NDFGQSVTSCFLKLI----IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G+ TS L ++ +P + L+ + A L C G P P + W+
Sbjct: 131 NSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATML-CAAGGNPDPEISWF 189
Query: 328 KDGEELKP----GDIHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASLL 372
KD + P G I ++ SG G Y C A+N G S+ + L
Sbjct: 190 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 243
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 59.3 bits (137), Expect = 2e-07
Identities = 75/296 (25%), Positives = 123/296 (41%), Gaps = 42/296 (14%)
Query: 99 RFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKP--GD---VYQLTGT---- 148
RF+ ++V G V +C+V+G P P + W K+ Q+L P GD V +G
Sbjct: 75 RFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQIS 134
Query: 149 ----NSLGSYCCIAKN-CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
+G Y C A+N + + AE+ + L++ + Q P V ++
Sbjct: 135 RLQPGDIGIYRCSARNPASSRTGNEAEVRI------LSDPGLHRQLYFLQRPSNVVAIEG 188
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+A ++ V+ P PS W R ++ + S+ + G L I + D
Sbjct: 189 KDAVLEGC------VSGYPPPSFTWLRGEEVIQLRSKKY---SLLGGSNLLISNVTDDDS 239
Query: 264 AEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQP 322
+ CV S L +++P P FL + + + E + EC V G P P
Sbjct: 240 GMYTCVVTYKNENISASAELTVLVP-----PWFLNHPSNLYAYESMDIEFECTVSGKPVP 294
Query: 323 VLKWYKDGEELKPGDIHRIISGQD----GTCSL--GTYTCEASNCMGVAASSASLL 372
+ W K+G+ + P D +I+ G + G G Y C A N G A +SA L+
Sbjct: 295 TVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLI 350
Score = 52.8 bits (121), Expect = 2e-05
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 11/87 (12%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F+ + + E + + FEC V G P P ++W K+G + P D +Q+ G ++L
Sbjct: 265 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGV 324
Query: 152 -----GSYCCIAKNCMGQASSSAELTV 173
G Y C+A+N G A +SA+L V
Sbjct: 325 VKSDEGFYQCVAENEAGNAQTSAQLIV 351
>AK092284-1|BAC03850.1| 885|Homo sapiens protein ( Homo sapiens
cDNA FLJ34965 fis, clone NTONG2004308. ).
Length = 885
Score = 59.3 bits (137), Expect = 2e-07
Identities = 61/225 (27%), Positives = 100/225 (44%), Gaps = 38/225 (16%)
Query: 98 PRF-MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLT---GTNSL- 151
PRF M + E F+C V+G PTP + W+K+ ++P ++ Y ++ G+++L
Sbjct: 661 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 720
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQ-------------NQLNEEEKLQL- 188
+Y C A NC+G+A LT+ D + + L EE L+
Sbjct: 721 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSN 780
Query: 189 ----FSKNQA----PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
F + Q P+F+ G+ A I F V P P++ WY+D + V + R
Sbjct: 781 YTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRR 839
Query: 241 CHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ + G L I +L D+ E++CVA N G + + L L
Sbjct: 840 FTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 884
Score = 51.6 bits (118), Expect = 4e-05
Identities = 72/300 (24%), Positives = 120/300 (40%), Gaps = 39/300 (13%)
Query: 92 PK-NYRKPRFMENL-QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------G 140
PK N P F+E L + + E + F +V G P P + W+++ L+P G
Sbjct: 457 PKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVG 516
Query: 141 DVYQLTGTNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK 196
+V L +N G Y C A N +G+A S A + DI Q L +Q
Sbjct: 517 NVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV---DIMPQEERVVALPPPVTHQHVM 573
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
+ ++ P ++V + + + + + V + + LD+
Sbjct: 574 EFDLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPD--FTPDHKSMIVSLDVL 631
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECK 315
F+D N + LK+ + PRF+ + E + +C
Sbjct: 632 PFNFVDP--------NMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCS 683
Query: 316 VIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVA 365
VIG+P P +KWYK+ ++P +I +IS + G+ +L TY C A NC+G A
Sbjct: 684 VIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEA 743
Score = 40.7 bits (91), Expect = 0.081
Identities = 24/105 (22%), Positives = 49/105 (46%)
Query: 181 NEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
++E K+ L P+F+ + + + F V P P + WY++ ++ +
Sbjct: 647 DKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNI 706
Query: 241 CHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
++ EE+G L I+ + D A ++C A N G+++ FL +
Sbjct: 707 KYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTM 751
Score = 39.1 bits (87), Expect = 0.25
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGE---------ELKPGDIHRIIS 343
PRF++ + + G A +C V G P+P + WYKDG+ E H +
Sbjct: 795 PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFI 854
Query: 344 GQDGTCSLGTYTCEASNCMGVAASSASL 371
G Y C A+N G+A S A+L
Sbjct: 855 TSLVKSDEGEYRCVATNKSGMAESFAAL 882
>AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein.
Length = 163
Score = 59.3 bits (137), Expect = 2e-07
Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFL 253
AP+F+ K+ + + + ++ P P + W +D QPV +R L ++ ++ L
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA-QDGDLYRL 67
Query: 254 DIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR--HYKKPRFLENLQAILSDEGA-V 310
I L D ++ C A N G++ + L++ + P FL +I EG+
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEA 127
Query: 311 NLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
C+V G P+P + W KDG L D R+
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRV 158
Score = 56.0 bits (129), Expect = 2e-06
Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 25/164 (15%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLT- 146
PRF+ +A + G + C++VG PTP +SW KD Q + + GD+Y+LT
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 147 ---GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKS 203
G Y C A+N +G+A ++ L V+ + QAP F+ S
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVD-----------AEAACAEQAPHFLLRPTS 118
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEE 247
+ + F +V P P++ W +D + + E + EE
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEE 162
Score = 41.5 bits (93), Expect = 0.046
Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Query: 288 PRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEEL---------KPGD 337
P+ PRFL +A + G L C+++G P P + W KD + + + GD
Sbjct: 4 PQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD 63
Query: 338 IHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
++R+ G Y C A N +G A ++ L
Sbjct: 64 LYRLTILDLALGDSGQYVCRARNAIGEAFAAVGL 97
>DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine
phosphatase receptor type F protein.
Length = 262
Score = 58.0 bits (134), Expect = 5e-07
Identities = 42/168 (25%), Positives = 74/168 (44%), Gaps = 5/168 (2%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 48 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 107
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGL-KSVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + +N KL + + Q P + + K+ E R + P+P +
Sbjct: 108 TATNSLGGINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 167
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFG 275
W++D PVD ++ K+ R L I++ E DQ +++CVA N G
Sbjct: 168 WFKDFLPVDPATSNGRIKQLRS-GALQIESSEESDQGKYECVATNSAG 214
Score = 39.1 bits (87), Expect = 0.25
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 17/174 (9%)
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFL-DQAEWKCVAF 271
F + P+P + W + + V S R + + + G L IQ L D+A ++C A
Sbjct: 52 FVCQATGEPKPRITWMKKGKKVS-SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTAT 110
Query: 272 NDFGQSVTSCFLKLI----IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G TS L ++ +P + L+ + A L C G P P + W+
Sbjct: 111 NSLGGINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATML-CAAGGNPDPEISWF 169
Query: 328 KDGEELKP----GDIHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASLL 372
KD + P G I ++ SG G Y C A+N G S+ + L
Sbjct: 170 KDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
>BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein
protein.
Length = 1263
Score = 58.0 bits (134), Expect = 5e-07
Identities = 61/225 (27%), Positives = 99/225 (44%), Gaps = 38/225 (16%)
Query: 98 PRF-MENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDV-YQLT---GTNSL- 151
PRF M + E F+C V+G PTP + W+K+ ++P ++ Y ++ G+ +L
Sbjct: 1039 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLK 1098
Query: 152 ---------GSYCCIAKNCMGQASSSAELTVEDIQ-------------NQLNEEEKLQL- 188
+Y C A NC+G+A LT+ D + + L EE L+
Sbjct: 1099 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSN 1158
Query: 189 ----FSKNQA----PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
F + Q P+F+ G+ A I F V P P++ WY+D + V + R
Sbjct: 1159 YTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLV-QGRR 1217
Query: 241 CHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
+ + G L I +L D+ E++CVA N G + + L L
Sbjct: 1218 FTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 1262
Score = 52.0 bits (119), Expect = 3e-05
Identities = 72/300 (24%), Positives = 120/300 (40%), Gaps = 39/300 (13%)
Query: 92 PK-NYRKPRFMENL-QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------G 140
PK N P F+E L + + E + F +V G P P + W+++ L+P G
Sbjct: 835 PKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVG 894
Query: 141 DVYQLTGTNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK 196
+V L +N G Y C A N +G+A S A + DI Q L +Q
Sbjct: 895 NVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANV---DIMPQEERVVALPPPVTHQHVM 951
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
+ ++ P ++V + + + + + V + + LD+
Sbjct: 952 EFDLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPE--FTPDHKSMIVSLDVL 1009
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECK 315
F+D N + LK+ + PRF+ + E + +C
Sbjct: 1010 PFNFVDP--------NMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCS 1061
Query: 316 VIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVA 365
VIG+P P +KWYK+ ++P +I +IS + G+ +L TY C A NC+G A
Sbjct: 1062 VIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVGEA 1121
Score = 42.3 bits (95), Expect = 0.027
Identities = 24/105 (22%), Positives = 50/105 (47%)
Query: 181 NEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSR 240
++E K+ L P+F+ + + + F V P P + WY++ ++ +
Sbjct: 1025 DKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNI 1084
Query: 241 CHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
++ EE+G + L I+ + D A ++C A N G+++ FL +
Sbjct: 1085 KYVISEEKGSYTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTM 1129
Score = 39.1 bits (87), Expect = 0.25
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGE---------ELKPGDIHRIIS 343
PRF++ + + G A +C V G P+P + WYKDG+ E H +
Sbjct: 1173 PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFI 1232
Query: 344 GQDGTCSLGTYTCEASNCMGVAASSASL 371
G Y C A+N G+A S A+L
Sbjct: 1233 TSLVKSDEGEYRCVATNKSGMAESFAAL 1260
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 58.0 bits (134), Expect = 5e-07
Identities = 66/227 (29%), Positives = 92/227 (40%), Gaps = 40/227 (17%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G+Y C A N +G AS+ +L V AP+ + V ++
Sbjct: 24 GTYTCRAVNELGDASAEIQLAV------------------GHAPQLTELPRDVTVELGRS 65
Query: 212 FRFTIKVAIPPEPSLLWYRDD-QPVDESSRCHLGKEER----GVFFLDIQALEFLDQAEW 266
+ P P++ W R D QP+ G R GV F + A E DQA +
Sbjct: 66 ALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPE--DQAPY 123
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVI-GVPQPVL 324
C A N FG+ +LI+ H P+ + + EG V+L C V+ G P P
Sbjct: 124 VCEARNVFGKVQAEA--RLIVTGH-APPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPER 180
Query: 325 KWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMG 363
W KDG L PG H I + DG+ L G Y+C A+N G
Sbjct: 181 HWLKDGRPLPPGSRHSIRA--DGSLHLDRALQEHAGRYSCVATNTAG 225
Score = 50.0 bits (114), Expect = 1e-04
Identities = 75/298 (25%), Positives = 111/298 (37%), Gaps = 44/298 (14%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVV-GFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
P+ + V EG VS C V+ G P P W KDG+ L PG + + SL
Sbjct: 148 PQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDR 207
Query: 152 ------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
G Y C+A N G EL V+ + +++ P H + +
Sbjct: 208 ALQEHAGRYSCVATNTAGSQHRDVELVVQ-VPPRIH-------------PTATHHITNEG 253
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
P + +P P++ W ++ + S H + G + + + D
Sbjct: 254 VPASLP---CVASGVPA-PTITWTKETNALT-SRGPHYNVSKEGTLLIAQPSAQ--DAGA 306
Query: 266 WKCVAFNDFGQSVTSCFLKLII-PR-HYKKPRFLE-NLQAILSDEGAVNLECKVIGVPQP 322
+ C A N G S L + PR H R + LQ V L+C+ G P P
Sbjct: 307 YVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVPLQVTAKAGEEVTLDCEAKGSPPP 366
Query: 323 VLKWYKDGEELKP--GDIHRIISG-----QDGTCSLGTYTCEASNCMGVAASSASLLG 373
++ W KD + P + SG Q G Y C ASN G +AS +LG
Sbjct: 367 LVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAG-SASHRYVLG 423
Score = 49.6 bits (113), Expect = 2e-04
Identities = 64/286 (22%), Positives = 111/286 (38%), Gaps = 22/286 (7%)
Query: 98 PRFMENLQAVLTEEGLVSF-ECKVVGFPTPVLSWFK-DGQELKPG-DVYQLTGTNSLGSY 154
P+ E + V E G + C+ G P P ++W + DGQ L + + + S
Sbjct: 49 PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG 108
Query: 155 CCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRF 214
++ + + ++ ++ E +L + + + P+ +V +P
Sbjct: 109 VLFFESVAPEDQAPYVCEARNVFGKVQAEARL-IVTGHAPPQIASSAPTVRVLEGQPVSL 167
Query: 215 T-IKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
I +A P P W +D +P+ SR + + G LD +AL+ + CVA N
Sbjct: 168 PCIVLAGRPLPERHWLKDGRPLPPGSRHSIRAD--GSLHLD-RALQE-HAGRYSCVATNT 223
Query: 274 FGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEE 332
G L + +P PR +++EG +L C GVP P + W K+
Sbjct: 224 AGSQHRDVELVVQVP-----PRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNA 278
Query: 333 LKPGDIHRIIS-------GQDGTCSLGTYTCEASNCMGVAASSASL 371
L H +S Q G Y C A+N +G ++ L
Sbjct: 279 LTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRL 324
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1a protein.
Length = 2053
Score = 58.0 bits (134), Expect = 5e-07
Identities = 52/242 (21%), Positives = 96/242 (39%), Gaps = 16/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V C + G P + W+++ + + P + + G ++ A Q S S
Sbjct: 332 VILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSA-----QKSHSGAYQC 386
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+ ++ + ++ P+ V E F P P++ W DD+
Sbjct: 387 FATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDE 446
Query: 234 PV--DESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ D S R + G + ++++ + D ++C A N G + + + P
Sbjct: 447 PIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 506
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R + N+ A+ + +N C+VIG P +KWYKD L D HR + ++GT
Sbjct: 507 SI---RAMRNITAVAGRDTLIN--CRVIGYPYYSIKWYKDA--LLLPDNHRQVVFENGTL 559
Query: 350 SL 351
L
Sbjct: 560 KL 561
Score = 42.3 bits (95), Expect = 0.027
Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 11/144 (7%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P + G S E + P P++ W +D +P+ SR + + L
Sbjct: 226 PTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRW-----TKRITGLT 280
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK-KPRFLENLQAILSDEGAVNLE 313
I L D + C N FG + + L +I P H P+ L+ V L
Sbjct: 281 ISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKT-----GIGSTVILS 335
Query: 314 CKVIGVPQPVLKWYKDGEELKPGD 337
C + G P+ ++WY++ E + P +
Sbjct: 336 CALTGSPEFTIRWYRNTELVLPDE 359
Score = 39.5 bits (88), Expect = 0.19
Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 12/133 (9%)
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDF-GQSVTSCFLKLIIPRHYKK-PRFLENLQAILSD 306
G++ D+Q + L + ++C+ + + G++ S +L + + P L+ +
Sbjct: 181 GLYISDVQKEDAL--STYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVW 238
Query: 307 EG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISGQD----GTCSLGTYTCEAS 359
G V L C G P P ++W KDG L P D + I+G T GTY CE +
Sbjct: 239 AGHTVELPCTASGYPIPAIRWLKDGRPL-PADSRWTKRITGLTISDLRTEDSGTYICEVT 297
Query: 360 NCMGVAASSASLL 372
N G A ++ L+
Sbjct: 298 NTFGSAEATGILM 310
Score = 38.3 bits (85), Expect = 0.43
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD---VYQLTG-------TNSLGSYCCIAKNCMG 163
V C G+P P + W KDG+ L P D ++TG T G+Y C N G
Sbjct: 243 VELPCTASGYPIPAIRWLKDGRPL-PADSRWTKRITGLTISDLRTEDSGTYICEVTNTFG 301
Query: 164 QASSSAELTVED 175
A ++ L V D
Sbjct: 302 SAEATGILMVID 313
Score = 35.9 bits (79), Expect = 2.3
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 12/74 (16%)
Query: 310 VNLECKVIGVPQPVLKWYKDGEELK---PGDIHRIISGQDGTCSL--------GTYTCEA 358
V L C +G P P +KW KD E+ D HR+I +GT L G YTC A
Sbjct: 1307 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIH-TNGTLLLRAVKAEDSGYYTCTA 1365
Query: 359 SNCMGVAASSASLL 372
+N G +LL
Sbjct: 1366 TNTGGFDTIIVNLL 1379
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 57.6 bits (133), Expect = 7e-07
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 51/282 (18%)
Query: 113 LVSFECKVVGFPTPVLSWFK-DGQELKPGDVY-------QLTGTNSL--GSYCCIAKNCM 162
++S EC G PTP++ W K DG K VY Q+ + G+Y CIAKN +
Sbjct: 281 VLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNAL 340
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + V+ AP ++ +++ E + P
Sbjct: 341 GAIHHTISVRVK------------------AAPYWITAPQNLVLSPGEDGTLICRANGNP 382
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
+P + W + P++ + K + + F ++Q A ++C A N++G + +
Sbjct: 383 KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS---SAVYQCNASNEYGYLLANA 439
Query: 282 FLKLIIPRHYKKPRFL---ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE-ELKPGD 337
F+ ++ + PR L L ++++ A+ L+C G P P ++W+K + D
Sbjct: 440 FVNVLA----EPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHED 494
Query: 338 IHRIISGQDGTC--------SLGTYTCEASNCMGVAASSASL 371
I+ + ++GT S GTYTC A N +G+A + L
Sbjct: 495 IY--VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 534
Score = 40.7 bits (91), Expect = 0.081
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 11/84 (13%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLS--WFKDGQELKPGDVYQL---------TGTNSLGSY 154
AV+ +VSFECKV T L+ W KD +EL + + + + G+Y
Sbjct: 549 AVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTY 608
Query: 155 CCIAKNCMGQASSSAELTVEDIQN 178
C+A + S+SA L+V D+ N
Sbjct: 609 TCVANTTLDSVSASAVLSVVDVPN 632
Score = 38.7 bits (86), Expect = 0.33
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 11/70 (15%)
Query: 117 ECKVVGFPTPVLSWFKDGQ-ELKPGDVYQL--TGT--------NSLGSYCCIAKNCMGQA 165
+C G P P + WFK + D+Y L GT +S G+Y C+A+N +G A
Sbjct: 469 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 528
Query: 166 SSSAELTVED 175
+ L ++D
Sbjct: 529 KNEVHLEIKD 538
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 57.6 bits (133), Expect = 7e-07
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 51/282 (18%)
Query: 113 LVSFECKVVGFPTPVLSWFK-DGQELKPGDVY-------QLTGTNSL--GSYCCIAKNCM 162
++S EC G PTP++ W K DG K VY Q+ + G+Y CIAKN +
Sbjct: 268 VLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNAL 327
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + V+ AP ++ +++ E + P
Sbjct: 328 GAIHHTISVRVK------------------AAPYWITAPQNLVLSPGEDGTLICRANGNP 369
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
+P + W + P++ + K + + F ++Q A ++C A N++G + +
Sbjct: 370 KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS---SAVYQCNASNEYGYLLANA 426
Query: 282 FLKLIIPRHYKKPRFL---ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE-ELKPGD 337
F+ ++ + PR L L ++++ A+ L+C G P P ++W+K + D
Sbjct: 427 FVNVLA----EPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHED 481
Query: 338 IHRIISGQDGTC--------SLGTYTCEASNCMGVAASSASL 371
I+ + ++GT S GTYTC A N +G+A + L
Sbjct: 482 IY--VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 521
Score = 38.7 bits (86), Expect = 0.33
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 11/70 (15%)
Query: 117 ECKVVGFPTPVLSWFKDGQ-ELKPGDVYQL--TGT--------NSLGSYCCIAKNCMGQA 165
+C G P P + WFK + D+Y L GT +S G+Y C+A+N +G A
Sbjct: 456 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 515
Query: 166 SSSAELTVED 175
+ L ++D
Sbjct: 516 KNEVHLEIKD 525
Score = 35.9 bits (79), Expect = 2.3
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLS--WFKDGQELKPGDVYQL---------TGTNSLGSY 154
AV+ +VSFECKV T L+ W KD +EL + + + + G+Y
Sbjct: 536 AVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTY 595
Query: 155 CCIAKNCMGQASSSAELTV 173
C+A + S+SA L+V
Sbjct: 596 TCVANTTLDSVSASAVLSV 614
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 57.6 bits (133), Expect = 7e-07
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 51/282 (18%)
Query: 113 LVSFECKVVGFPTPVLSWFK-DGQELKPGDVY-------QLTGTNSL--GSYCCIAKNCM 162
++S EC G PTP++ W K DG K VY Q+ + G+Y CIAKN +
Sbjct: 268 VLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNAL 327
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + V+ AP ++ +++ E + P
Sbjct: 328 GAIHHTISVRVK------------------AAPYWITAPQNLVLSPGEDGTLICRANGNP 369
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
+P + W + P++ + K + + F ++Q A ++C A N++G + +
Sbjct: 370 KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS---SAVYQCNASNEYGYLLANA 426
Query: 282 FLKLIIPRHYKKPRFL---ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE-ELKPGD 337
F+ ++ + PR L L ++++ A+ L+C G P P ++W+K + D
Sbjct: 427 FVNVLA----EPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHED 481
Query: 338 IHRIISGQDGTC--------SLGTYTCEASNCMGVAASSASL 371
I+ + ++GT S GTYTC A N +G+A + L
Sbjct: 482 IY--VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 521
Score = 38.7 bits (86), Expect = 0.33
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 11/70 (15%)
Query: 117 ECKVVGFPTPVLSWFKDGQ-ELKPGDVYQL--TGT--------NSLGSYCCIAKNCMGQA 165
+C G P P + WFK + D+Y L GT +S G+Y C+A+N +G A
Sbjct: 456 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 515
Query: 166 SSSAELTVED 175
+ L ++D
Sbjct: 516 KNEVHLEIKD 525
Score = 35.9 bits (79), Expect = 2.3
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLS--WFKDGQELKPGDVYQL---------TGTNSLGSY 154
AV+ +VSFECKV T L+ W KD +EL + + + + G+Y
Sbjct: 536 AVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTY 595
Query: 155 CCIAKNCMGQASSSAELTV 173
C+A + S+SA L+V
Sbjct: 596 TCVANTTLDSVSASAVLSV 614
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 57.6 bits (133), Expect = 7e-07
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 51/282 (18%)
Query: 113 LVSFECKVVGFPTPVLSWFK-DGQELKPGDVY-------QLTGTNSL--GSYCCIAKNCM 162
++S EC G PTP++ W K DG K VY Q+ + G+Y CIAKN +
Sbjct: 281 VLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNAL 340
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + V+ AP ++ +++ E + P
Sbjct: 341 GAIHHTISVRVK------------------AAPYWITAPQNLVLSPGEDGTLICRANGNP 382
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
+P + W + P++ + K + + F ++Q A ++C A N++G + +
Sbjct: 383 KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS---SAVYQCNASNEYGYLLANA 439
Query: 282 FLKLIIPRHYKKPRFL---ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE-ELKPGD 337
F+ ++ + PR L L ++++ A+ L+C G P P ++W+K + D
Sbjct: 440 FVNVLA----EPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHED 494
Query: 338 IHRIISGQDGTC--------SLGTYTCEASNCMGVAASSASL 371
I+ + ++GT S GTYTC A N +G+A + L
Sbjct: 495 IY--VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 534
Score = 40.7 bits (91), Expect = 0.081
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 11/84 (13%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLS--WFKDGQELKPGDVYQL---------TGTNSLGSY 154
AV+ +VSFECKV T L+ W KD +EL + + + + G+Y
Sbjct: 549 AVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTY 608
Query: 155 CCIAKNCMGQASSSAELTVEDIQN 178
C+A + S+SA L+V D+ N
Sbjct: 609 TCVANTTLDSVSASAVLSVVDVPN 632
Score = 38.7 bits (86), Expect = 0.33
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 11/70 (15%)
Query: 117 ECKVVGFPTPVLSWFKDGQ-ELKPGDVYQL--TGT--------NSLGSYCCIAKNCMGQA 165
+C G P P + WFK + D+Y L GT +S G+Y C+A+N +G A
Sbjct: 469 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 528
Query: 166 SSSAELTVED 175
+ L ++D
Sbjct: 529 KNEVHLEIKD 538
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 57.6 bits (133), Expect = 7e-07
Identities = 59/211 (27%), Positives = 98/211 (46%), Gaps = 19/211 (9%)
Query: 107 VLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQAS 166
V+ EE V + C+ G P PV+ W K G +L + + + +L A++ GQ
Sbjct: 429 VVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTL-RIDRAAQHDQGQYE 487
Query: 167 SSA--ELTVEDIQNQLNEEEK-LQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPE 223
A L V+ + QL + K L +F+ Q P+ SVE + + + P+
Sbjct: 488 CQAVSSLGVKKVSVQLTVKPKALAVFT--QLPQDT----SVE--VGKNINISCHAQGEPQ 539
Query: 224 PSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFL 283
P + W ++ + ES + H+ ++ G L I F DQ ++CVA N FG +VT+ FL
Sbjct: 540 PIITWNKEGVQITESGKFHV--DDEGT--LTIYDAGFPDQGRYECVARNSFGLAVTNMFL 595
Query: 284 KL-IIPRHYKKPRFLEN--LQAILSDEGAVN 311
+ I F+E+ L A+ + A+N
Sbjct: 596 TVTAIQGRQAGDDFVESSILDAVQRVDSAIN 626
Score = 54.8 bits (126), Expect = 5e-06
Identities = 67/289 (23%), Positives = 107/289 (37%), Gaps = 26/289 (8%)
Query: 94 NYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLG 152
N + PR Q V G V F C+ G P P + W + L D+ T N
Sbjct: 230 NCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSL---DLEDDTRLNVFD 286
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQA-PKFVHGLKSVEAKIDEP 211
+ +N + + + + + +S A P FV + E I
Sbjct: 287 DGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTS 346
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
P P + W RD+ + SR H+ G++ +Q + D + C A
Sbjct: 347 TTLECMATGHPHPLITWTRDNGLELDGSR-HVATSS-GLY---LQNITQRDHGRFTCHAN 401
Query: 272 NDFGQSVTSCFLKLIIPRHYKKPRF-LENLQAILSDEGAVNLECKVIGVPQPVLKWYKDG 330
N G + + + P P+F + ++ +E AV C+ G P PV+ W K G
Sbjct: 402 NSHGTVQAAANIIVQAP-----PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTG 456
Query: 331 EELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
+L H ++S GT + G Y C+A + +GV S L
Sbjct: 457 GQLPVEGQHTVLS--SGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQL 503
Score = 53.6 bits (123), Expect = 1e-05
Identities = 47/186 (25%), Positives = 78/186 (41%), Gaps = 9/186 (4%)
Query: 193 QAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF 252
Q+P+ + VE FT + P+P ++W ++ +D L + G
Sbjct: 232 QSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGT-- 289
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVN 311
L I+ DQ ++C+A N G++ T + L KP F+ Q G +
Sbjct: 290 LMIRNTRESDQGVYQCMARNSAGEAKTQSAM-LRYSSLPAKPSFVIQPQDTEVLIGTSTT 348
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHRIISG----QDGTC-SLGTYTCEASNCMGVAA 366
LEC G P P++ W +D G H S Q+ T G +TC A+N G
Sbjct: 349 LECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQ 408
Query: 367 SSASLL 372
++A+++
Sbjct: 409 AAANII 414
Score = 43.2 bits (97), Expect = 0.015
Identities = 72/317 (22%), Positives = 120/317 (37%), Gaps = 54/317 (17%)
Query: 75 QRRFKSIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKD- 133
+ + +S + ++S P P +P+ E L T + EC G P P+++W +D
Sbjct: 313 EAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTST-----TLECMATGHPHPLITWTRDN 367
Query: 134 GQEL--------KPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
G EL G Q G + C A N G ++A + V+ Q K
Sbjct: 368 GLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQ-APPQFTVTPK 426
Query: 186 LQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGK 245
Q+ + A +++ EA + P P ++W + + + H
Sbjct: 427 DQVVLEEHAVEWL-----CEADGNPP------------PVIVWTKTGGQLPVEGQ-HTVL 468
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILS 305
G +D A DQ +++C A + G S L + KP+ L +
Sbjct: 469 SS-GTLRIDRAAQH--DQGQYECQAVSSLGVKKVSVQLTV-------KPKALAVFTQLPQ 518
Query: 306 DEGA-----VNLECKVIGVPQPVLKWYKDGEEL-KPGDIHRIISG-----QDGTCSLGTY 354
D +N+ C G PQP++ W K+G ++ + G H G G G Y
Sbjct: 519 DTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRY 578
Query: 355 TCEASNCMGVAASSASL 371
C A N G+A ++ L
Sbjct: 579 ECVARNSFGLAVTNMFL 595
>AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar to
hemicentin (LOC392395) protein.
Length = 746
Score = 57.6 bits (133), Expect = 7e-07
Identities = 75/275 (27%), Positives = 117/275 (42%), Gaps = 53/275 (19%)
Query: 118 CKVVGFPTPVLSWFKDGQEL--KPGDVYQLTGTN---------SLGSYCCIAKNCMGQAS 166
C+V+G L+W +D + L G V QL + G Y C+A N G
Sbjct: 501 CRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTR 560
Query: 167 SSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSL 226
+S L V E ++ + + +Q H + VE K+ + + P P +
Sbjct: 561 ASVWLLVR-------EAPQVSIHTSSQ-----HFSQGVEVKV------SCSASGYPTPHI 602
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W R+ Q + E SR H+ + +G L IQ + D + C A N+ G + L
Sbjct: 603 SWSRESQALQEDSRIHV--DAQGT--LIIQGVAPEDAGNYSCQATNEVGTDQETVTL--- 655
Query: 287 IPRHYKKPRFLENLQAILS---DEGAVNLECKVIGVPQPVLKWYKDGEEL-------KPG 336
+Y P + + A++ E AV L C+ GVP P + WY+ G E+ G
Sbjct: 656 ---YYTDPPSVSAVNAVVLVAVGEEAV-LVCEASGVPPPRVIWYRGGLEMILAPEGSSSG 711
Query: 337 DIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
+ RI + Q+ GTYTC A N +G A++ L
Sbjct: 712 KL-RIPAAQER--DAGTYTCRAVNELGDASAEIQL 743
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 57.6 bits (133), Expect = 7e-07
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 51/282 (18%)
Query: 113 LVSFECKVVGFPTPVLSWFK-DGQELKPGDVY-------QLTGTNSL--GSYCCIAKNCM 162
++S EC G PTP++ W K DG K VY Q+ + G+Y CIAKN +
Sbjct: 282 VLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNAL 341
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + V+ AP ++ +++ E + P
Sbjct: 342 GAIHHTISVRVK------------------AAPYWITAPQNLVLSPGEDGTLICRANGNP 383
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
+P + W + P++ + K + + F ++Q A ++C A N++G + +
Sbjct: 384 KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS---SAVYQCNASNEYGYLLANA 440
Query: 282 FLKLIIPRHYKKPRFL---ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE-ELKPGD 337
F+ ++ + PR L L ++++ A+ L+C G P P ++W+K + D
Sbjct: 441 FVNVLA----EPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIQWFKGAKGSALHED 495
Query: 338 IHRIISGQDGTC--------SLGTYTCEASNCMGVAASSASL 371
I+ + ++GT S GTYTC A N +G+A + L
Sbjct: 496 IY--VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 535
Score = 38.7 bits (86), Expect = 0.33
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 11/70 (15%)
Query: 117 ECKVVGFPTPVLSWFKDGQ-ELKPGDVYQL--TGT--------NSLGSYCCIAKNCMGQA 165
+C G P P + WFK + D+Y L GT +S G+Y C+A+N +G A
Sbjct: 470 DCAFFGSPLPTIQWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 529
Query: 166 SSSAELTVED 175
+ L ++D
Sbjct: 530 KNEVHLEIKD 539
Score = 35.9 bits (79), Expect = 2.3
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLS--WFKDGQELKPGDVYQL---------TGTNSLGSY 154
AV+ +VSFECKV T L+ W KD +EL + + + + G+Y
Sbjct: 550 AVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTY 609
Query: 155 CCIAKNCMGQASSSAELTV 173
C+A + S+SA L+V
Sbjct: 610 TCVANTTLDSVSASAVLSV 628
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus
protein.
Length = 1236
Score = 57.6 bits (133), Expect = 7e-07
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 51/282 (18%)
Query: 113 LVSFECKVVGFPTPVLSWFK-DGQELKPGDVY-------QLTGTNSL--GSYCCIAKNCM 162
++S EC G PTP++ W K DG K VY Q+ + G+Y CIAKN +
Sbjct: 287 VLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNAL 346
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + V+ AP ++ +++ E + P
Sbjct: 347 GAIHHTISVRVK------------------AAPYWITAPQNLVLSPGEDGTLICRANGNP 388
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
+P + W + P++ + K + + F ++Q A ++C A N++G + +
Sbjct: 389 KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS---SAVYQCNASNEYGYLLANA 445
Query: 282 FLKLIIPRHYKKPRFL---ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE-ELKPGD 337
F+ ++ + PR L L ++++ A+ L+C G P P ++W+K + D
Sbjct: 446 FVNVLA----EPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHED 500
Query: 338 IHRIISGQDGTC--------SLGTYTCEASNCMGVAASSASL 371
I+ + ++GT S GTYTC A N +G+A + L
Sbjct: 501 IY--VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 540
Score = 38.7 bits (86), Expect = 0.33
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 11/70 (15%)
Query: 117 ECKVVGFPTPVLSWFKDGQ-ELKPGDVYQL--TGT--------NSLGSYCCIAKNCMGQA 165
+C G P P + WFK + D+Y L GT +S G+Y C+A+N +G A
Sbjct: 475 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 534
Query: 166 SSSAELTVED 175
+ L ++D
Sbjct: 535 KNEVHLEIKD 544
Score = 35.9 bits (79), Expect = 2.3
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLS--WFKDGQELKPGDVYQL---------TGTNSLGSY 154
AV+ +VSFECKV T L+ W KD +EL + + + + G+Y
Sbjct: 555 AVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTY 614
Query: 155 CCIAKNCMGQASSSAELTV 173
C+A + S+SA L+V
Sbjct: 615 TCVANTTLDSVSASAVLSV 633
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 57.6 bits (133), Expect = 7e-07
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 51/282 (18%)
Query: 113 LVSFECKVVGFPTPVLSWFK-DGQELKPGDVY-------QLTGTNSL--GSYCCIAKNCM 162
++S EC G PTP++ W K DG K VY Q+ + G+Y CIAKN +
Sbjct: 287 VLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNAL 346
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + V+ AP ++ +++ E + P
Sbjct: 347 GAIHHTISVRVK------------------AAPYWITAPQNLVLSPGEDGTLICRANGNP 388
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
+P + W + P++ + K + + F ++Q A ++C A N++G + +
Sbjct: 389 KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS---SAVYQCNASNEYGYLLANA 445
Query: 282 FLKLIIPRHYKKPRFL---ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE-ELKPGD 337
F+ ++ + PR L L ++++ A+ L+C G P P ++W+K + D
Sbjct: 446 FVNVLA----EPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHED 500
Query: 338 IHRIISGQDGTC--------SLGTYTCEASNCMGVAASSASL 371
I+ + ++GT S GTYTC A N +G+A + L
Sbjct: 501 IY--VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 540
Score = 38.7 bits (86), Expect = 0.33
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 11/70 (15%)
Query: 117 ECKVVGFPTPVLSWFKDGQ-ELKPGDVYQL--TGT--------NSLGSYCCIAKNCMGQA 165
+C G P P + WFK + D+Y L GT +S G+Y C+A+N +G A
Sbjct: 475 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 534
Query: 166 SSSAELTVED 175
+ L ++D
Sbjct: 535 KNEVHLEIKD 544
Score = 35.9 bits (79), Expect = 2.3
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLS--WFKDGQELKPGDVYQL---------TGTNSLGSY 154
AV+ +VSFECKV T L+ W KD +EL + + + + G+Y
Sbjct: 555 AVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTY 614
Query: 155 CCIAKNCMGQASSSAELTV 173
C+A + S+SA L+V
Sbjct: 615 TCVANTTLDSVSASAVLSV 633
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 57.6 bits (133), Expect = 7e-07
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 51/282 (18%)
Query: 113 LVSFECKVVGFPTPVLSWFK-DGQELKPGDVY-------QLTGTNSL--GSYCCIAKNCM 162
++S EC G PTP++ W K DG K VY Q+ + G+Y CIAKN +
Sbjct: 275 VLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNAL 334
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
G + + V+ AP ++ +++ E + P
Sbjct: 335 GAIHHTISVRVK------------------AAPYWITAPQNLVLSPGEDGTLICRANGNP 376
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERG-VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
+P + W + P++ + K + + F ++Q A ++C A N++G + +
Sbjct: 377 KPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERS---SAVYQCNASNEYGYLLANA 433
Query: 282 FLKLIIPRHYKKPRFL---ENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGE-ELKPGD 337
F+ ++ + PR L L ++++ A+ L+C G P P ++W+K + D
Sbjct: 434 FVNVLA----EPPRILTPANTLYQVIANRPAL-LDCAFFGSPLPTIEWFKGAKGSALHED 488
Query: 338 IHRIISGQDGTC--------SLGTYTCEASNCMGVAASSASL 371
I+ + ++GT S GTYTC A N +G+A + L
Sbjct: 489 IY--VLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHL 528
Score = 38.7 bits (86), Expect = 0.33
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 11/70 (15%)
Query: 117 ECKVVGFPTPVLSWFKDGQ-ELKPGDVYQL--TGT--------NSLGSYCCIAKNCMGQA 165
+C G P P + WFK + D+Y L GT +S G+Y C+A+N +G A
Sbjct: 463 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMA 522
Query: 166 SSSAELTVED 175
+ L ++D
Sbjct: 523 KNEVHLEIKD 532
Score = 35.9 bits (79), Expect = 2.3
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Query: 106 AVLTEEGLVSFECKVVGFPTPVLS--WFKDGQELKPGDVYQL---------TGTNSLGSY 154
AV+ +VSFECKV T L+ W KD +EL + + + + G+Y
Sbjct: 543 AVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTY 602
Query: 155 CCIAKNCMGQASSSAELTV 173
C+A + S+SA L+V
Sbjct: 603 TCVANTTLDSVSASAVLSV 621
>BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein
protein.
Length = 143
Score = 57.2 bits (132), Expect = 9e-07
Identities = 45/136 (33%), Positives = 63/136 (46%), Gaps = 14/136 (10%)
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI-LSDE 307
GV L I+ + D + C+A N GQ+ S L + +K P F+E LQ ++D
Sbjct: 2 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 61
Query: 308 GAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG---TCSL---------GTYT 355
V LEC+V+GVP P + W K+ E L R+ QD C L G YT
Sbjct: 62 YPVRLECRVLGVPPPQIFWKKENESL-THSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 120
Query: 356 CEASNCMGVAASSASL 371
A N G+ + +A L
Sbjct: 121 VSAKNEAGIVSCTARL 136
Score = 40.3 bits (90), Expect = 0.11
Identities = 38/140 (27%), Positives = 56/140 (40%), Gaps = 14/140 (10%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y CIA N GQ S S EL V E K P F+ L++ P
Sbjct: 17 GIYTCIATNRAGQNSFSLELVV-----AAKEAHK--------PPVFIEKLQNTGVADGYP 63
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESS-RCHLGKEERGVFFLDIQALEFLDQAEWKCVA 270
R +V P P + W ++++ + S+ R + ++ G L IQ D + A
Sbjct: 64 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 123
Query: 271 FNDFGQSVTSCFLKLIIPRH 290
N+ G + L + I RH
Sbjct: 124 KNEAGIVSCTARLDVYISRH 143
Score = 35.5 bits (78), Expect = 3.0
Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 95 YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL 137
++ P F+E LQ +G V EC+V+G P P + W K+ + L
Sbjct: 44 HKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL 87
>AJ314900-1|CAC85747.1| 551|Homo sapiens obscurin protein.
Length = 551
Score = 56.8 bits (131), Expect = 1e-06
Identities = 78/288 (27%), Positives = 129/288 (44%), Gaps = 38/288 (13%)
Query: 88 HPTVPKN-YRKPRFMEN-LQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N +QA ++S C+V T V +W+KDG++L
Sbjct: 89 HITEPKMMFAKEQSVHNEVQAEAGASAMLS--CEVAQAQTEV-TWYKDGKKLSSSSK--- 142
Query: 146 TGTNSLGSYCCIAKNCMGQASS---SAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLK 202
G G + G+A + S E + + L+ E +F+K Q+ VH
Sbjct: 143 VGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQS---VHN-- 197
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFL 261
V+A+ + +VA P+ + WY+D + + SS+ + E +G L +Q +
Sbjct: 198 EVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRM--EVKGCTRRLVVQQVGKA 254
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YKKPRFLENLQAILSDEGA-VNLECKVIGV 319
D E+ C A GQ V S L + P+ + K + + N + ++ GA L C+V
Sbjct: 255 DAGEYSCEAG---GQRV-SFQLHITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQA 308
Query: 320 PQPVLKWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
Q + WYKDG++L G + +++ Q G G YTCEA
Sbjct: 309 -QTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA 355
Score = 51.2 bits (117), Expect = 6e-05
Identities = 61/255 (23%), Positives = 105/255 (41%), Gaps = 26/255 (10%)
Query: 115 SFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVE 174
+ C+V T V+ W+KDG++L + S E +
Sbjct: 24 TLSCEVAQAQTEVM-WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 82
Query: 175 DIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+ +L+ E +F+K Q+ VH V+A+ + +VA + + WY+D +
Sbjct: 83 RVSFRLHITEPKMMFAKEQS---VHN--EVQAEAGASAMLSCEVA-QAQTEVTWYKDGKK 136
Query: 235 VDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRH-YK 292
+ SS+ +G E +G L + D E+ C A GQ V S L + P+ +
Sbjct: 137 LSSSSK--VGMEVKGCTRRLVLPQAGKADAGEYSCEAG---GQRV-SFHLHITEPKGVFA 190
Query: 293 KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELK---------PGDIHRIIS 343
K + + N + ++ G + + PQ + WYKDG++L G R++
Sbjct: 191 KEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVV 248
Query: 344 GQDGTCSLGTYTCEA 358
Q G G Y+CEA
Sbjct: 249 QQVGKADAGEYSCEA 263
Score = 48.4 bits (110), Expect = 4e-04
Identities = 67/283 (23%), Positives = 108/283 (38%), Gaps = 28/283 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLT 146
H T PK + K + + N V E G + V P ++W+KDG++L ++
Sbjct: 181 HITEPKGVFAKEQSVHN--EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRME 238
Query: 147 GTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEA 206
S E + + QL+ E +F+K Q VH EA
Sbjct: 239 VKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQ---LVHNEVRTEA 295
Query: 207 KIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAE 265
+ A + + WY+D + + SS+ + E G L +Q D E
Sbjct: 296 GASATLSCEVAQA---QTEVTWYKDGKKLSSSSKVRI--EAAGCMRQLVVQQAGQADAGE 350
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-NLECKVIGVPQPVL 324
+ C A G S L + P+ L + + + ++ GA+ L C+V Q +
Sbjct: 351 YTCEA----GGQRLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCEVAQA-QTEV 404
Query: 325 KWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
WYKDG++L G R++ Q G Y+CEA
Sbjct: 405 TWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 447
Score = 48.0 bits (109), Expect = 5e-04
Identities = 66/285 (23%), Positives = 111/285 (38%), Gaps = 28/285 (9%)
Query: 88 HPTVPKN-YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
H T PK + K + + N V TE G + C+V T V +W+KDG++L ++
Sbjct: 273 HITEPKAVFAKEQLVHN--EVRTEAGASATLSCEVAQAQTEV-TWYKDGKKLSSSSKVRI 329
Query: 146 TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
+ + E + + L+ E +F+K Q H + V+
Sbjct: 330 EAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQ---LAH--RKVQ 384
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQA 264
A+ + +VA + + WY+D + + SS+ + E G L +Q D
Sbjct: 385 AEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRM--EAVGCTRRLVVQQACQADTG 441
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVL 324
E+ C A G S L + P+ + + + L C+V V+
Sbjct: 442 EYSCEA----GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVM 497
Query: 325 KWYKDGEELK---------PGDIHRIISGQDGTCSLGTYTCEASN 360
WYKDG++L G R++ Q G G Y+CEA +
Sbjct: 498 -WYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGS 541
>AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.
Length = 1598
Score = 56.8 bits (131), Expect = 1e-06
Identities = 48/163 (29%), Positives = 71/163 (43%), Gaps = 19/163 (11%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P PS+ WY+D V+ + G L I L D ++C A N G+ TS
Sbjct: 13 PPPSITWYKDAAVVEVEKLTRFRQRNDGG--LQISGLVPDDTGMFQCFARNAAGEVQTST 70
Query: 282 FLKL--IIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIH 339
+L + I P + P L + + D +V L C+ G P+P + W K L G +
Sbjct: 71 YLAVTSIAPNITRGP-----LDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQ 125
Query: 340 --RIISGQDGTCSL--------GTYTCEASNCMGVAASSASLL 372
R + G+ + GTYTC A+N GV +SA L+
Sbjct: 126 LPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV 168
Score = 34.3 bits (75), Expect = 7.0
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 8/70 (11%)
Query: 310 VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNC 361
V++ C+ GVP P + WYKD ++ + R DG + G + C A N
Sbjct: 3 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNA 62
Query: 362 MGVAASSASL 371
G +S L
Sbjct: 63 AGEVQTSTYL 72
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell
adhesion molecule 2 protein.
Length = 2113
Score = 56.4 bits (130), Expect = 2e-06
Identities = 52/242 (21%), Positives = 95/242 (39%), Gaps = 16/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V C + G P + W+++ + + P + + G ++ A Q S S
Sbjct: 392 VILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSA-----QKSHSGAYQC 446
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+ ++ + ++ P+ V E F P P++ W DD+
Sbjct: 447 FATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDE 506
Query: 234 PV--DESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ D S R + G + +++ + D ++C A N G + + + P
Sbjct: 507 PIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 566
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R + N+ A+ + +N C+VIG P +KWYKD L D HR + ++GT
Sbjct: 567 SI---RAMRNITAVAGRDTLIN--CRVIGYPYYSIKWYKDA--LLLPDNHRQVVFENGTL 619
Query: 350 SL 351
L
Sbjct: 620 KL 621
Score = 42.3 bits (95), Expect = 0.027
Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 11/144 (7%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P + G S E + P P++ W +D +P+ SR + + L
Sbjct: 286 PTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRW-----TKRITGLT 340
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK-KPRFLENLQAILSDEGAVNLE 313
I L D + C N FG + + L +I P H P+ L+ V L
Sbjct: 341 ISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKT-----GIGSTVILS 395
Query: 314 CKVIGVPQPVLKWYKDGEELKPGD 337
C + G P+ ++WY++ E + P +
Sbjct: 396 CALTGSPEFTIRWYRNTELVLPDE 419
Score = 39.5 bits (88), Expect = 0.19
Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 12/133 (9%)
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDF-GQSVTSCFLKLIIPRHYKK-PRFLENLQAILSD 306
G++ D+Q + L + ++C+ + + G++ S +L + + P L+ +
Sbjct: 241 GLYISDVQKEDAL--STYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVW 298
Query: 307 EG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RIISGQD----GTCSLGTYTCEAS 359
G V L C G P P ++W KDG L P D + I+G T GTY CE +
Sbjct: 299 AGHTVELPCTASGYPIPAIRWLKDGRPL-PADSRWTKRITGLTISDLRTEDSGTYICEVT 357
Query: 360 NCMGVAASSASLL 372
N G A ++ L+
Sbjct: 358 NTFGSAEATGILM 370
Score = 38.3 bits (85), Expect = 0.43
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD---VYQLTG-------TNSLGSYCCIAKNCMG 163
V C G+P P + W KDG+ L P D ++TG T G+Y C N G
Sbjct: 303 VELPCTASGYPIPAIRWLKDGRPL-PADSRWTKRITGLTISDLRTEDSGTYICEVTNTFG 361
Query: 164 QASSSAELTVED 175
A ++ L V D
Sbjct: 362 SAEATGILMVID 373
Score = 35.9 bits (79), Expect = 2.3
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 12/74 (16%)
Query: 310 VNLECKVIGVPQPVLKWYKDGEELK---PGDIHRIISGQDGTCSL--------GTYTCEA 358
V L C +G P P +KW KD E+ D HR+I +GT L G YTC A
Sbjct: 1367 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIH-TNGTLLLRAVKAEDSGYYTCTA 1425
Query: 359 SNCMGVAASSASLL 372
+N G +LL
Sbjct: 1426 TNTGGFDTIIVNLL 1439
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule DSCAML1 protein.
Length = 2053
Score = 56.4 bits (130), Expect = 2e-06
Identities = 52/242 (21%), Positives = 95/242 (39%), Gaps = 16/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V C + G P + W+++ + + P + + G ++ A Q S S
Sbjct: 332 VILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSA-----QKSHSGAYQC 386
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+ ++ + ++ P+ V E F P P++ W DD+
Sbjct: 387 FATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDE 446
Query: 234 PV--DESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ D S R + G + +++ + D ++C A N G + + + P
Sbjct: 447 PIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 506
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R + N+ A+ + +N C+VIG P +KWYKD L D HR + ++GT
Sbjct: 507 SI---RAMRNITAVAGRDTLIN--CRVIGYPYYSIKWYKDA--LLLPDNHRQVVFENGTL 559
Query: 350 SL 351
L
Sbjct: 560 KL 561
Score = 42.3 bits (95), Expect = 0.027
Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 11/144 (7%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P + G S E + P P++ W +D +P+ SR + + L
Sbjct: 226 PTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRW-----TKRITGLT 280
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK-KPRFLENLQAILSDEGAVNLE 313
I L D + C N FG + + L +I P H P+ L+ V L
Sbjct: 281 ISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKT-----GIGSTVILS 335
Query: 314 CKVIGVPQPVLKWYKDGEELKPGD 337
C + G P+ ++WY++ E + P +
Sbjct: 336 CALTGSPEFTIRWYRNTELVLPDE 359
Score = 39.9 bits (89), Expect = 0.14
Identities = 39/154 (25%), Positives = 68/154 (44%), Gaps = 13/154 (8%)
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF-GQSVTSCFLKLI 286
W +D + +R + G++ D+Q + L + ++C+ + + G++ S +L
Sbjct: 161 WEKDTVSIIPENRFFI-TYHGGLYISDVQKEDAL--STYRCITKHKYSGETRQSNGARLS 217
Query: 287 IPRHYKK-PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RII 342
+ + P L+ + G V L C G P P ++W KDG L P D + I
Sbjct: 218 VTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPL-PADSRWTKRI 276
Query: 343 SGQD----GTCSLGTYTCEASNCMGVAASSASLL 372
+G T GTY CE +N G A ++ L+
Sbjct: 277 TGLTISDLRTEDSGTYICEVTNTFGSAEATGILM 310
Score = 38.3 bits (85), Expect = 0.43
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD---VYQLTG-------TNSLGSYCCIAKNCMG 163
V C G+P P + W KDG+ L P D ++TG T G+Y C N G
Sbjct: 243 VELPCTASGYPIPAIRWLKDGRPL-PADSRWTKRITGLTISDLRTEDSGTYICEVTNTFG 301
Query: 164 QASSSAELTVED 175
A ++ L V D
Sbjct: 302 SAEATGILMVID 313
Score = 35.9 bits (79), Expect = 2.3
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 12/74 (16%)
Query: 310 VNLECKVIGVPQPVLKWYKDGEELK---PGDIHRIISGQDGTCSL--------GTYTCEA 358
V L C +G P P +KW KD E+ D HR+I +GT L G YTC A
Sbjct: 1307 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIH-TNGTLLLRAVKAEDSGYYTCTA 1365
Query: 359 SNCMGVAASSASLL 372
+N G +LL
Sbjct: 1366 TNTGGFDTIIVNLL 1379
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1b protein.
Length = 1842
Score = 56.4 bits (130), Expect = 2e-06
Identities = 52/242 (21%), Positives = 95/242 (39%), Gaps = 16/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V C + G P + W+++ + + P + + G ++ A Q S S
Sbjct: 121 VILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSA-----QKSHSGAYQC 175
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+ ++ + ++ P+ V E F P P++ W DD+
Sbjct: 176 FATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDE 235
Query: 234 PV--DESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ D S R + G + +++ + D ++C A N G + + + P
Sbjct: 236 PIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 295
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R + N+ A+ + +N C+VIG P +KWYKD L D HR + ++GT
Sbjct: 296 SI---RAMRNITAVAGRDTLIN--CRVIGYPYYSIKWYKDA--LLLPDNHRQVVFENGTL 348
Query: 350 SL 351
L
Sbjct: 349 KL 350
Score = 41.5 bits (93), Expect = 0.046
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 11/117 (9%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W +D +P+ SR + + L I L D + C N FG + +
Sbjct: 42 PIPAIRWLKDGRPLPADSRW-----TKRITGLTISDLRTEDSGTYICEVTNTFGSAEATG 96
Query: 282 FLKLIIPRHYK-KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD 337
L +I P H P+ L+ V L C + G P+ ++WY++ E + P +
Sbjct: 97 ILMVIDPLHVTLTPKKLKT-----GIGSTVILSCALTGSPEFTIRWYRNTELVLPDE 148
Score = 40.7 bits (91), Expect = 0.081
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 9/97 (9%)
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIH-- 339
FL L+ H +P + ++D ++ L C G P P ++W KDG L P D
Sbjct: 6 FLLLLDSLHKARPEDVGTSLYFVND--SLQLPCTAPGYPIPAIRWLKDGRPL-PADSRWT 62
Query: 340 RIISGQD----GTCSLGTYTCEASNCMGVAASSASLL 372
+ I+G T GTY CE +N G A ++ L+
Sbjct: 63 KRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILM 99
Score = 37.1 bits (82), Expect = 1.00
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 11/68 (16%)
Query: 118 CKVVGFPTPVLSWFKDGQELKPGD---VYQLTG-------TNSLGSYCCIAKNCMGQASS 167
C G+P P + W KDG+ L P D ++TG T G+Y C N G A +
Sbjct: 36 CTAPGYPIPAIRWLKDGRPL-PADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEA 94
Query: 168 SAELTVED 175
+ L V D
Sbjct: 95 TGILMVID 102
Score = 35.9 bits (79), Expect = 2.3
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 12/74 (16%)
Query: 310 VNLECKVIGVPQPVLKWYKDGEELK---PGDIHRIISGQDGTCSL--------GTYTCEA 358
V L C +G P P +KW KD E+ D HR+I +GT L G YTC A
Sbjct: 1096 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIH-TNGTLLLRAVKAEDSGYYTCTA 1154
Query: 359 SNCMGVAASSASLL 372
+N G +LL
Sbjct: 1155 TNTGGFDTIIVNLL 1168
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 56.4 bits (130), Expect = 2e-06
Identities = 52/242 (21%), Positives = 95/242 (39%), Gaps = 16/242 (6%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
V C + G P + W+++ + + P + + G ++ A Q S S
Sbjct: 371 VILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSA-----QKSHSGAYQC 425
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQ 233
+ ++ + ++ P+ V E F P P++ W DD+
Sbjct: 426 FATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDE 485
Query: 234 PV--DESSRCHLGKEERG--VFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
P+ D S R + G + +++ + D ++C A N G + + + P
Sbjct: 486 PIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 545
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTC 349
R + N+ A+ + +N C+VIG P +KWYKD L D HR + ++GT
Sbjct: 546 SI---RAMRNITAVAGRDTLIN--CRVIGYPYYSIKWYKDA--LLLPDNHRQVVFENGTL 598
Query: 350 SL 351
L
Sbjct: 599 KL 600
Score = 42.3 bits (95), Expect = 0.027
Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 11/144 (7%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P + G S E + P P++ W +D +P+ SR + + L
Sbjct: 265 PTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRW-----TKRITGLT 319
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK-KPRFLENLQAILSDEGAVNLE 313
I L D + C N FG + + L +I P H P+ L+ V L
Sbjct: 320 ISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKT-----GIGSTVILS 374
Query: 314 CKVIGVPQPVLKWYKDGEELKPGD 337
C + G P+ ++WY++ E + P +
Sbjct: 375 CALTGSPEFTIRWYRNTELVLPDE 398
Score = 39.9 bits (89), Expect = 0.14
Identities = 39/154 (25%), Positives = 68/154 (44%), Gaps = 13/154 (8%)
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF-GQSVTSCFLKLI 286
W +D + +R + G++ D+Q + L + ++C+ + + G++ S +L
Sbjct: 200 WEKDTVSIIPENRFFI-TYHGGLYISDVQKEDAL--STYRCITKHKYSGETRQSNGARLS 256
Query: 287 IPRHYKK-PRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIH--RII 342
+ + P L+ + G V L C G P P ++W KDG L P D + I
Sbjct: 257 VTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPL-PADSRWTKRI 315
Query: 343 SGQD----GTCSLGTYTCEASNCMGVAASSASLL 372
+G T GTY CE +N G A ++ L+
Sbjct: 316 TGLTISDLRTEDSGTYICEVTNTFGSAEATGILM 349
Score = 38.3 bits (85), Expect = 0.43
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGD---VYQLTG-------TNSLGSYCCIAKNCMG 163
V C G+P P + W KDG+ L P D ++TG T G+Y C N G
Sbjct: 282 VELPCTASGYPIPAIRWLKDGRPL-PADSRWTKRITGLTISDLRTEDSGTYICEVTNTFG 340
Query: 164 QASSSAELTVED 175
A ++ L V D
Sbjct: 341 SAEATGILMVID 352
Score = 35.9 bits (79), Expect = 2.3
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 12/74 (16%)
Query: 310 VNLECKVIGVPQPVLKWYKDGEELK---PGDIHRIISGQDGTCSL--------GTYTCEA 358
V L C +G P P +KW KD E+ D HR+I +GT L G YTC A
Sbjct: 1346 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIH-TNGTLLLRAVKAEDSGYYTCTA 1404
Query: 359 SNCMGVAASSASLL 372
+N G +LL
Sbjct: 1405 TNTGGFDTIIVNLL 1418
>BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein.
Length = 227
Score = 55.6 bits (128), Expect = 3e-06
Identities = 48/177 (27%), Positives = 79/177 (44%), Gaps = 16/177 (9%)
Query: 124 PTPVLSWFKDGQELKPG--DVYQLTGT--NSLGSYCCIA--KNCMGQASSSAELTVEDIQ 177
P + SW GQ L P ++Q TG ++G +A G+ SS+ T
Sbjct: 39 PLALPSW-NQGQRLSPTLVSIFQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNA 97
Query: 178 NQLNEEEKLQLFSKNQA-------PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
+L E+ Q F + A P F ++ +E RF K+ P+P ++W++
Sbjct: 98 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 157
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
DDQ + ES + +E G L I + D A++ C A N G++ +C +LI+
Sbjct: 158 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 212
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 103 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 162
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 163 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 211
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 117 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 176
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 177 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 224
>BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein.
Length = 236
Score = 55.6 bits (128), Expect = 3e-06
Identities = 48/177 (27%), Positives = 79/177 (44%), Gaps = 16/177 (9%)
Query: 124 PTPVLSWFKDGQELKPG--DVYQLTGT--NSLGSYCCIA--KNCMGQASSSAELTVEDIQ 177
P + SW GQ L P ++Q TG ++G +A G+ SS+ T
Sbjct: 38 PLALPSW-NQGQRLSPTLVSIFQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNA 96
Query: 178 NQLNEEEKLQLFSKNQA-------PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
+L E+ Q F + A P F ++ +E RF K+ P+P ++W++
Sbjct: 97 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 156
Query: 231 DDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
DDQ + ES + +E G L I + D A++ C A N G++ +C +LI+
Sbjct: 157 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 211
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 102 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 161
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 162 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 210
Score = 53.6 bits (123), Expect = 1e-05
Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 15/119 (12%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 116 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 175
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK 196
SL Y C A N +G+A+ +AEL VE ++ E E+ + K + K
Sbjct: 176 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEEQKKKKKKK 234
>BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein.
Length = 353
Score = 55.2 bits (127), Expect = 4e-06
Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 9/173 (5%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 48 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 107
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGL-KSVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 108 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 167
Query: 228 WYRDDQPVDESSRCHLGKEERG-----VFFLDIQALEFLDQAEWKCVAFNDFG 275
W++D PVD ++ K+ R L I++ E DQ +++CVA N G
Sbjct: 168 WFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKYECVATNSAG 220
Score = 36.7 bits (81), Expect = 1.3
Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 23/180 (12%)
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFL-DQAEWKCVAF 271
F + P+P + W + + V S R + + + G L IQ L D+A ++C A
Sbjct: 52 FVCQATGEPKPRITWMKKGKKVS-SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTAT 110
Query: 272 NDFGQSVTSCFLKLI----IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G+ TS L ++ +P + L+ + A L C G P P + W+
Sbjct: 111 NSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATML-CAAGGNPDPEISWF 169
Query: 328 KDGEELKP----GDIHRIISGQD---GTCSL--------GTYTCEASNCMGVAASSASLL 372
KD + P G I ++ SG G + G Y C A+N G S+ + L
Sbjct: 170 KDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKYECVATNSAGTRYSAPANL 229
>AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 353
Score = 55.2 bits (127), Expect = 4e-06
Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 9/173 (5%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAEL 171
G+ SF C+ G P P ++W K G+++ + + GS I + + + E
Sbjct: 48 GVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYEC 107
Query: 172 TVEDIQNQLNEEEKLQLFSKNQAPKFVHGL-KSVEAKIDEPFRFTIKVAIP---PEPSLL 227
T + ++N KL + + Q P + + K+ E R + P+P +
Sbjct: 108 TATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEIS 167
Query: 228 WYRDDQPVDESSRCHLGKEERG-----VFFLDIQALEFLDQAEWKCVAFNDFG 275
W++D PVD ++ K+ R L I++ E DQ +++CVA N G
Sbjct: 168 WFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKYECVATNSAG 220
Score = 36.7 bits (81), Expect = 1.3
Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 23/180 (12%)
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGV-FFLDIQALEFL-DQAEWKCVAF 271
F + P+P + W + + V S R + + + G L IQ L D+A ++C A
Sbjct: 52 FVCQATGEPKPRITWMKKGKKVS-SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTAT 110
Query: 272 NDFGQSVTSCFLKLI----IPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
N G+ TS L ++ +P + L+ + A L C G P P + W+
Sbjct: 111 NSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATML-CAAGGNPDPEISWF 169
Query: 328 KDGEELKP----GDIHRIISGQD---GTCSL--------GTYTCEASNCMGVAASSASLL 372
KD + P G I ++ SG G + G Y C A+N G S+ + L
Sbjct: 170 KDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKYECVATNSAGTRYSAPANL 229
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 55.2 bits (127), Expect = 4e-06
Identities = 67/286 (23%), Positives = 117/286 (40%), Gaps = 34/286 (11%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIA 158
+F E L A + V EC +G P P ++W + D + L + +
Sbjct: 124 QFPETLPAA--KGSTVKLECFALGNPIPQINW-------RRSDGLPFSSKIKLRKFSGVL 174
Query: 159 K--NCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTI 216
+ N + + S E E+ + + +L ++K P +V +K VE +++ +
Sbjct: 175 EIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAK---PHWVQLIKDVEIAVEDSLYWEC 231
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQ 276
+ + P+PS W ++ + R + E G L I L D ++C+A N G
Sbjct: 232 RASGKPKPSYRWLKNGAALVLEERTQI---ENGA--LTISNLSVTDSGMFQCIAENKHGL 286
Query: 277 SVTSCFLKLII--PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELK 334
+S LK++ P K P ++ L + V+L+CK P+ + W K ++
Sbjct: 287 VYSSAELKVVASAPDFSKNP--MKKLVQVQVGS-LVSLDCKPRASPRALSSWKKGDVSVQ 343
Query: 335 PGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASLL 372
+ RI DG + GTYTC A N G A + L+
Sbjct: 344 EHE--RISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLV 387
Score = 42.7 bits (96), Expect = 0.020
Identities = 64/248 (25%), Positives = 97/248 (39%), Gaps = 35/248 (14%)
Query: 95 YRKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQ-----LTGT 148
Y KP +++ ++ V + E + +EC+ G P P W K+G L + Q LT +
Sbjct: 207 YAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTIS 266
Query: 149 N----SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV 204
N G + CIA+N G SSAEL V FSKN K V
Sbjct: 267 NLSVTDSGMFQCIAENKHGLVYSSAELKV---------VASAPDFSKNPMKKL------V 311
Query: 205 EAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQA 264
+ ++ K P W + D V E R L + G L I + D
Sbjct: 312 QVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISL-LNDGG---LKIANVTKADAG 367
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QP 322
+ C+A N FG++ + L + P N+ + + +V L C+V P
Sbjct: 368 TYTCMAENQFGKANGTTHLVVTEPTRITLAP--SNMDVSVGE--SVILPCQVQHDPLLDI 423
Query: 323 VLKWYKDG 330
+ WY +G
Sbjct: 424 IFTWYFNG 431
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 54.8 bits (126), Expect = 5e-06
Identities = 61/246 (24%), Positives = 99/246 (40%), Gaps = 22/246 (8%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP P+ N A EE ++F C+ G P P +SWF++G+ ++ + Y L G+N+
Sbjct: 207 VPPAISMPQKSFNATAERGEE--MTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNT 264
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
+N + +S V N+ E+EK Q F + + LK+ +
Sbjct: 265 E----LTVRNII---NSDGGPYVCRATNKAGEDEK-QAFLQVFVQPHIIQLKNETTYENG 316
Query: 211 PFRFTIKVAIPPEPSLLWYR--DDQPVDESSRCHLG----KEERGVFFLDIQALEFLDQA 264
P P + W R D E + G K + G L I+ ++ D
Sbjct: 317 QVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSG 376
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPV 323
+ C A + G S +L + Y P+F+ N S EG +N+ C V P
Sbjct: 377 RYDCEAASRIGGHQKSMYLDI----EY-APKFISNQTIYYSWEGNPINISCDVKSNPPAS 431
Query: 324 LKWYKD 329
+ W +D
Sbjct: 432 IHWRRD 437
Score = 53.6 bits (123), Expect = 1e-05
Identities = 67/294 (22%), Positives = 120/294 (40%), Gaps = 43/294 (14%)
Query: 95 YRKPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELK--PGDVYQLTGTNSL 151
Y+K F E + ++G C+V P P +SW +E+ + + + N+L
Sbjct: 112 YQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNL 171
Query: 152 GSYCCIAKN------CMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVE 205
I K+ C G+ + E+ DI +N + + K+ +
Sbjct: 172 -QILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKS---------FNAT 221
Query: 206 AKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAE 265
A+ E F+ + + PEP++ W+R+ + ++E+ + L L ++ + D
Sbjct: 222 AERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTE---LTVRNIINSDGGP 278
Query: 266 WKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLK 325
+ C A N G+ FL++ + +P ++ + G V L C G P P +
Sbjct: 279 YVCRATNKAGEDEKQAFLQVFV-----QPHIIQLKNETTYENGQVTLVCDAEGEPIPEIT 333
Query: 326 WYK--DGEELKPGDIH---RI-ISGQDGTCSL----------GTYTCEASNCMG 363
W + DG GD RI + GQ G+ SL G Y CEA++ +G
Sbjct: 334 WKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIG 387
>BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein.
Length = 697
Score = 54.8 bits (126), Expect = 5e-06
Identities = 43/159 (27%), Positives = 75/159 (47%), Gaps = 16/159 (10%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P+P+ W ++ +P+ R + E+G L+I + D ++C+A N G ++
Sbjct: 15 PKPTYKWLKNGEPLLTRDRIQI---EQGT--LNITIVNLSDAGMYQCLAENKHGVIFSNA 69
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
L +I L+ + ++ G V +ECK P+PV W K + LK + RI
Sbjct: 70 ELSVIAVGPDFSRTLLKRV-TLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENE--RI 126
Query: 342 ISGQDGTCSL--------GTYTCEASNCMGVAASSASLL 372
+DG + G+YTC A+N G A+S+ +L+
Sbjct: 127 TISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLV 165
Score = 40.7 bits (91), Expect = 0.081
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 10/74 (13%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----------GSYCCIAKNC 161
G V ECK P PV +W K LK + ++ +L GSY CIA N
Sbjct: 95 GEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNH 154
Query: 162 MGQASSSAELTVED 175
G ASS+ L V+D
Sbjct: 155 FGTASSTGNLVVKD 168
Score = 40.3 bits (90), Expect = 0.11
Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 9/69 (13%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKPGDVYQL-TGT--------NSLGSYCCIAKNCMGQ 164
V +ECK G P P W K+G+ L D Q+ GT + G Y C+A+N G
Sbjct: 5 VFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGV 64
Query: 165 ASSSAELTV 173
S+AEL+V
Sbjct: 65 IFSNAELSV 73
Score = 39.1 bits (87), Expect = 0.25
Identities = 25/64 (39%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Query: 313 ECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ-----DGTCSLGTYTCEASNCMGVAAS 367
ECK G P+P KW K+GE L D +I G G Y C A N GV S
Sbjct: 8 ECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFS 67
Query: 368 SASL 371
+A L
Sbjct: 68 NAEL 71
>X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase
protein.
Length = 458
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 334 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 393
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 394 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 442
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 348 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 407
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 408 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 455
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 5/125 (4%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQA---PKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
S ++ L E ++++ + L+ ++ + P F ++ +E RF K+ P
Sbjct: 321 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 380
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P ++W++DDQ + ES + +E G L I + D A++ C A N G++ +C
Sbjct: 381 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCT 438
Query: 283 LKLII 287
+LI+
Sbjct: 439 AELIV 443
>X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase
protein.
Length = 991
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 867 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 926
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 927 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 975
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 881 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 940
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 941 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 988
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 5/125 (4%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQA---PKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
S ++ L E ++++ + L+ ++ + P F ++ +E RF K+ P
Sbjct: 854 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 913
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P ++W++DDQ + ES + +E G L I + D A++ C A N G++ +C
Sbjct: 914 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCT 971
Query: 283 LKLII 287
+LI+
Sbjct: 972 AELIV 976
Score = 45.6 bits (103), Expect = 0.003
Identities = 44/154 (28%), Positives = 69/154 (44%), Gaps = 18/154 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F + LQ V EG + +C+V P + W +G+ LK L+ SL
Sbjct: 176 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 235
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLN-EEEKLQLFSKNQAPKFVHGLK 202
G Y C+AKN GQA S ++TV+D N + +++ +P V G +
Sbjct: 236 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSPPPVLGTE 295
Query: 203 SVEAKIDEPFRFT-IKVAIPPEPSLLWYRDDQPV 235
S +P T K A+PP+ ++ + +DQ V
Sbjct: 296 SDATVKKKPAPKTPPKAAMPPQ--IIQFPEDQKV 327
Score = 36.3 bits (80), Expect = 1.7
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Query: 166 SSSAELTVEDIQNQLN--------EEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
S+S E +D++N +N + + + S+ AP F L+ V + +
Sbjct: 139 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 198
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ P +++W + + + ++++ + +E + + I+ D+ +KCVA ND GQ+
Sbjct: 199 VSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 257
Query: 278 VTSC 281
SC
Sbjct: 258 ECSC 261
>BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein.
Length = 166
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 42 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 101
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 102 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 150
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 56 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 115
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 116 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 163
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 61 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 120
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 121 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 151
>BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein.
Length = 167
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 43 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 102
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 103 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 151
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 57 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 116
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 117 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 164
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 62 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 121
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 122 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 152
>BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 29 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 88
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 89 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 137
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 150
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 5/125 (4%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQA---PKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
S ++ L E ++++ + L+ ++ + P F ++ +E RF K+ P
Sbjct: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P ++W++DDQ + ES + +E G L I + D A++ C A N G++ +C
Sbjct: 76 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCT 133
Query: 283 LKLII 287
+LI+
Sbjct: 134 AELIV 138
>BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 30 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 89
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 90 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 151
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 139
>BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 30 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 89
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 90 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 151
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 139
>BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 29 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 88
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 89 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 137
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 150
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 5/125 (4%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQA---PKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
S ++ L E ++++ + L+ ++ + P F ++ +E RF K+ P
Sbjct: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P ++W++DDQ + ES + +E G L I + D A++ C A N G++ +C
Sbjct: 76 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCT 133
Query: 283 LKLII 287
+LI+
Sbjct: 134 AELIV 138
>AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein
isoform 2 protein.
Length = 154
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 30 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 89
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 90 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 151
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 139
>AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein
isoform 1 protein.
Length = 153
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 29 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 88
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 89 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 137
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 150
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 5/125 (4%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQA---PKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
S ++ L E ++++ + L+ ++ + P F ++ +E RF K+ P
Sbjct: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P ++W++DDQ + ES + +E G L I + D A++ C A N G++ +C
Sbjct: 76 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCT 133
Query: 283 LKLII 287
+LI+
Sbjct: 134 AELIV 138
>AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein
protein.
Length = 154
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 30 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 89
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 90 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 138
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 104 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 151
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 139
>AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein
protein.
Length = 153
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 29 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 88
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 89 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 137
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 103 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 150
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 5/125 (4%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQA---PKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
S ++ L E ++++ + L+ ++ + P F ++ +E RF K+ P
Sbjct: 16 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 75
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P ++W++DDQ + ES + +E G L I + D A++ C A N G++ +C
Sbjct: 76 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCT 133
Query: 283 LKLII 287
+LI+
Sbjct: 134 AELIV 138
>AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle
myosin light chain kinase protein.
Length = 300
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 176 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 235
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 236 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 284
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 190 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 249
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 250 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 297
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 5/125 (4%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQA---PKFVHGLKSVEAKIDEPFRFTIKVAIPP 222
S ++ L E ++++ + L+ ++ + P F ++ +E RF K+ P
Sbjct: 163 SPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 222
Query: 223 EPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCF 282
+P ++W++DDQ + ES + +E G L I + D A++ C A N G++ +C
Sbjct: 223 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA--TCT 280
Query: 283 LKLII 287
+LI+
Sbjct: 281 AELIV 285
>AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kinase
protein.
Length = 992
Score = 54.4 bits (125), Expect = 6e-06
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 12/109 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 868 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 927
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSASLL 372
+ +I +DG CSL YTC+A N +G A +A L+
Sbjct: 928 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 976
Score = 52.8 bits (121), Expect = 2e-05
Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 882 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 941
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AEL VE ++ E E+
Sbjct: 942 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 989
Score = 49.2 bits (112), Expect = 2e-04
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 887 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 946
Query: 255 IQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
I + D A++ C A N G++ +C +LI+
Sbjct: 947 ISDVCGDDDAKYTCKAVNSLGEA--TCTAELIV 977
Score = 44.0 bits (99), Expect = 0.009
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL----- 151
P F + LQ V EG + +C+V P + W +G+ LK L+ SL
Sbjct: 176 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 235
Query: 152 --------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEE--EKLQLFSKNQAPKFVHGL 201
G Y C+AKN GQA S ++TV+D N + E K+ P +
Sbjct: 236 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 295
Query: 202 KSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPV 235
K + K A+PP+ ++ + +DQ V
Sbjct: 296 SDATVKKKPAPKTPPKAAMPPQ--IIQFPEDQKV 327
Score = 36.3 bits (80), Expect = 1.7
Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 9/124 (7%)
Query: 166 SSSAELTVEDIQNQLN--------EEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
S+S E +D++N +N + + + S+ AP F L+ V + +
Sbjct: 139 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 198
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
V+ P +++W + + + ++++ + +E + + I+ D+ +KCVA ND GQ+
Sbjct: 199 VSSDPPATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 257
Query: 278 VTSC 281
SC
Sbjct: 258 ECSC 261
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 54.0 bits (124), Expect = 8e-06
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 21/192 (10%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD---DQPVDESSRCHLGKEER 248
N P F + + R P P + W +D D P R H+ E+
Sbjct: 600 NMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDD 659
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENL--QAILSD 306
F +D++ +E D + C A N G + L ++ + P FL L + +
Sbjct: 660 VFFIVDVK-IE--DIGVYSCTAQNSAGSISANATLTVL-----ETPSFLRPLLDRTVTKG 711
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------DGTCS-LGTYTCEAS 359
E AV L+C G P P L W KD L + H +G D S G YTCE S
Sbjct: 712 ETAV-LQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMS 770
Query: 360 NCMGVAASSASL 371
N +G + L
Sbjct: 771 NTLGTERGNVRL 782
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 15/130 (11%)
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-N 311
L ++ +EF + +++CV N FG S S KL + P F + + GA+
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSY-SVKAKLTVNM---LPSFTKTPMDLTIRAGAMAR 621
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHR--IISGQDGTC--------SLGTYTCEASNC 361
LEC +G P P + W KDG P R + +D +G Y+C A N
Sbjct: 622 LECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNS 681
Query: 362 MGVAASSASL 371
G +++A+L
Sbjct: 682 AGSISANATL 691
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 54.0 bits (124), Expect = 8e-06
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 21/192 (10%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD---DQPVDESSRCHLGKEER 248
N P F + + R P P + W +D D P R H+ E+
Sbjct: 600 NMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDD 659
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENL--QAILSD 306
F +D++ +E D + C A N G + L ++ + P FL L + +
Sbjct: 660 VFFIVDVK-IE--DIGVYSCTAQNSAGSISANATLTVL-----ETPSFLRPLLDRTVTKG 711
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------DGTCS-LGTYTCEAS 359
E AV L+C G P P L W KD L + H +G D S G YTCE S
Sbjct: 712 ETAV-LQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMS 770
Query: 360 NCMGVAASSASL 371
N +G + L
Sbjct: 771 NTLGTERGNVRL 782
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 15/130 (11%)
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-N 311
L ++ +EF + +++CV N FG S S KL + P F + + GA+
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSY-SVKAKLTVNM---LPSFTKTPMDLTIRAGAMAR 621
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHR--IISGQDGTC--------SLGTYTCEASNC 361
LEC +G P P + W KDG P R + +D +G Y+C A N
Sbjct: 622 LECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNS 681
Query: 362 MGVAASSASL 371
G +++A+L
Sbjct: 682 AGSISANATL 691
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 54.0 bits (124), Expect = 8e-06
Identities = 84/398 (21%), Positives = 186/398 (46%), Gaps = 37/398 (9%)
Query: 2602 IDTAEIKSVVGKITDNLFSIEAAQSIEVKE-DFSDVKSTD-LRVTDSVTEVLESSDVRVI 2659
+D AE + +V ++ D L ++ A+ I+VKE + K + +V D+ T L++++ +++
Sbjct: 717 LDKAEDQHLV-EMEDTLNKLQEAE-IKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLL 774
Query: 2660 E--NVSKSDDVPTNINLLVDDSLLEIDKAVKSTEALKNIPQRDLAENEQQLGEDTTGSKQ 2717
+ + K+ + + L +K +K E KN + ++L G +
Sbjct: 775 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITREL----QGREL 830
Query: 2718 KVVELPDTIDDVSQDMIVEHLPTSEVKLLEGQLLAAEENTLSEALKSSLVTVQKT--TET 2775
K+ L + + +VSQ V+ E+++L+ + A E +S +S TV K E
Sbjct: 831 KLTNLQENLSEVSQ---VKETLEKELQILKEKFAEASEEAVS-VQRSMQETVNKLHQKEE 886
Query: 2776 PLDDTSVDLVKIAGE-PEIKSKLVEELQTIADSKSQKMIEESTTRETVESPLITTGKTT- 2833
+ S DL K+ ++++K E+ D + +++I+ +E +E+ + K +
Sbjct: 887 QFNMLSSDLEKLRENLADMEAKFREK-----DEREEQLIK---AKEKLENDIAEIMKMSG 938
Query: 2834 ETPNDITSMNVGETEKQRKESITELNQKSSDFTKSQSIVSDVSQEILV--EHLISDEIKF 2891
+ P+ +T MN + + ++ + EL K + ++ S + +++ V E + K
Sbjct: 939 DNPSQLTKMN--DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKK 996
Query: 2892 TKEQQLAKEDLTAEVNLPLVTGHETIQTLNSNLENEMCES-LKIEQAV-----SAETTES 2945
+E++ E +++ + T H Q L + E E+ K E+ + + TE
Sbjct: 997 HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTED 1056
Query: 2946 TVESQRVASEVILELVSEQLKKDQAESSNSQTAENIVR 2983
++ R + +L+ + E+L+K ++ +QTAE+ ++
Sbjct: 1057 KLKGAREENSGLLQEL-EELRKQAEKAKAAQTAEDAMQ 1093
Score = 39.9 bits (89), Expect = 0.14
Identities = 123/586 (20%), Positives = 237/586 (40%), Gaps = 50/586 (8%)
Query: 2452 KQLQKSITISESVIEPNIETEPNPQSPVY--LASQLKMALLVLYNQDIESLEVMAPHLTK 2509
K+L++ + +E I+ ++E E N +S + +L+ L L N EV T
Sbjct: 791 KKLRQQLEAAEKQIK-HLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETL 849
Query: 2510 DK-LKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVEQDLNSPEEIDEIF 2568
+K L+++ E ++ V ++Q N + + ++ N++ DL E
Sbjct: 850 EKELQILKEKFAEASEEAVSVQRSMQETVN----KLHQKEEQFNMLSSDLEKLRENLADM 905
Query: 2569 ETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKITDNLFSIEAAQSIE 2628
E K ++ Q I K E D AEI + G L + +
Sbjct: 906 EAKFREKDEREEQLI----------KAKEKLEN-DIAEIMKMSGDNPSQLTKMN--DELR 952
Query: 2629 VKEDFSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPTNINLLVDDSLLEIDKAV- 2687
+KE DV+ L++T + E + + K++ ++ E+++ +
Sbjct: 953 LKE--RDVEELQLKLTKA-NENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 1009
Query: 2688 ---KSTEALKNIPQRDLAENEQQLGEDTTGSKQKVVELPDTIDDVSQDMIVEHLPTSEV- 2743
K E N Q A E+ E T ++ + L T+ D + S +
Sbjct: 1010 DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLL 1069
Query: 2744 KLLEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKSKLVEELQT 2803
+ LE AE+ ++ + ++ +++ T+ + + L + + +KL EL T
Sbjct: 1070 QELEELRKQAEKAKAAQTAEDAMQIMEQMTK----EKTETLASLEDTKQTNAKLQNELDT 1125
Query: 2804 IADSKSQKMIEESTTRE--TVESPLITT-GKTTETPNDITSMNVGETEKQRKESIT---E 2857
+ ++ + + E + ++E TVE+ + K ET + + ++E++ E
Sbjct: 1126 LKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEE 1185
Query: 2858 LNQKSSDFTKSQSIVSD--VSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHE 2915
L + + T Q + + V L+E + E KF K+ K L +++ E
Sbjct: 1186 LGRSRDEVTSHQKLEEERSVLNNQLLE-MKKRESKFIKDADEEKASLQKSISITSALLTE 1244
Query: 2916 TIQTLNSNLENEMCESLKIEQAV--SAETTESTVESQRVASEVILELVSEQLK--KDQAE 2971
L L NE+ L+ E A S + T+ES +V E+ ++ + QLK K Q
Sbjct: 1245 KDAELEK-LRNEVTV-LRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLS 1302
Query: 2972 SSNSQT-AENIVREIVVTSEITALETLGLPLERSGNDGDL-VELLS 3015
SS+ T + E S+I L ++ + L+R D + VE++S
Sbjct: 1303 SSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMS 1348
Score = 37.9 bits (84), Expect = 0.57
Identities = 70/362 (19%), Positives = 149/362 (41%), Gaps = 30/362 (8%)
Query: 751 INPLSEILSITDTIQESASETIEVQRTLFSRLPKPLKVLQQTLTIIEKCIDVESD---NR 807
++ S I+ + + E E++R L S KP + +L+++++ ++ R
Sbjct: 506 VSEKSRIMELEKDLALRVQEVAELRRRLESN--KPAGDVDMSLSLLQEISSLQEKLEVTR 563
Query: 808 TLVKKTCVSIMEKCGNAIQNLVSEINAIEKKEYLLLSEN--VCNELDVVSNEISTVVNFS 865
T ++ S+ E G + EI A+ L EN + ++L+ + E S V+
Sbjct: 564 TDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALW 623
Query: 866 TESIKTNNLLNETT--EVKLE-------STVESKHL-TDTQKALFELKGPLRSLLYIVDS 915
++T ++ E+K+ T E L T +K + + + +L DS
Sbjct: 624 KSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDS 683
Query: 916 AESGKIVDISQVNNSEV-ILNDMSASIQDLQSALEQIESLSVLECATSLNKYNTEIIENV 974
+ ++ + + ++ + S++ ++S L++ E ++E +LNK I+
Sbjct: 684 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 743
Query: 975 MEPVLQLRSS-----FEKMSTEIKA-EDKI----QLNKVLSSIKENLTVISSYINKVENN 1024
VLQ + + + ++++KA E+K+ L K S K + + + E
Sbjct: 744 ELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQ 803
Query: 1025 IGAFDVLQNENKLEALQKMAETLISLEKNLPTL-DTMPQVQGNMNSFHKNLTKALEKVIE 1083
I ++ +N +A + L E L L + + +V + K L EK E
Sbjct: 804 IKHLEIEKNAESSKA-SSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAE 862
Query: 1084 SN 1085
++
Sbjct: 863 AS 864
Score = 34.3 bits (75), Expect = 7.0
Identities = 60/301 (19%), Positives = 130/301 (43%), Gaps = 15/301 (4%)
Query: 676 DELIKE-QTIIATETEMEGKQVMTNEEFRVSMTNVSTSLNKVINDXXXXXXXXXXXSELM 734
+EL K+ + A +T + Q+M + T S K N + L
Sbjct: 1073 EELRKQAEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLK 1132
Query: 735 ASAATASKSLEIISSLINPLSEILSITDTIQESASETIEVQRTLFSRLPKPLKVLQQTLT 794
+ +KS E+++ + E +T++++A++ + L K + L ++
Sbjct: 1133 -NVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRD 1191
Query: 795 IIEKCIDVESDNRTLVKKTCVSIMEKCGNAIQNLVSEINAIEKKEYL---LLSENVCNEL 851
+ +E + R+++ + + ++ I++ E +++K + LL+E EL
Sbjct: 1192 EVTSHQKLEEE-RSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDA-EL 1249
Query: 852 DVVSNEISTV--VNFSTESIKTNNLLNETTEVKLESTVESKHLTDTQKALFELKGPLRSL 909
+ + NE++ + N S +S+ + E+ +VKLE V++ L L E K L S
Sbjct: 1250 EKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQ-----LKENKRQLSSS 1304
Query: 910 LYIVDS-AESGKIVDISQVNNSEVILNDMSASIQDLQSALEQIESLSVLECATSLNKYNT 968
D+ A+ + SQ++ ++ D+ QDL+ +E + ++ LN Y++
Sbjct: 1305 SGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDS 1364
Query: 969 E 969
+
Sbjct: 1365 D 1365
>BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.
Length = 1028
Score = 54.0 bits (124), Expect = 8e-06
Identities = 64/285 (22%), Positives = 117/285 (41%), Gaps = 32/285 (11%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFK-DGQELKPGDVYQLTGTNSLGSYCCI 157
RF E +QA ++ V EC +G P P +SW + DG L PG V S
Sbjct: 232 RFPETIQAA--KDSSVKLECFALGNPVPDISWRRLDGSPL-PGKVKY-----SKSQAILE 283
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
N + E +++ + + +L ++ P++ +++ I + + K
Sbjct: 284 IPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAP---PEWEQKIQNTHLSIYDNLLWECK 340
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+ P P W ++ + ++ R + E G L I L D ++C A N +
Sbjct: 341 ASGKPNPWYTWLKNGERLNPEERIQI---ENGT--LIITMLNVSDSGVYQCAAENKYQII 395
Query: 278 VTSCFLKLII--PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ L+++ P K P ++ + G + + CK P+ + W + E L+
Sbjct: 396 YANAELRVLASAPDFSKSP---VKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQ 452
Query: 336 GDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASLL 372
RI +DG+ + G+YTC A+N G A ++ SL+
Sbjct: 453 SK--RIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLI 495
Score = 39.9 bits (89), Expect = 0.14
Identities = 39/182 (21%), Positives = 74/182 (40%), Gaps = 11/182 (6%)
Query: 95 YRKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
Y P + + +Q L+ + +ECK G P P +W K+G+ L P + Q+ + +
Sbjct: 315 YAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIIT 374
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
++ + + Q ++ + + +L FSK+ K KS ++
Sbjct: 375 MLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKK-----KSF-VQVGGDIV 428
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
K P ++ W R + + +S R L ++ L I + D + C+A N
Sbjct: 429 IGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGS----LKIYNITRSDAGSYTCIATNQ 484
Query: 274 FG 275
FG
Sbjct: 485 FG 486
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 54.0 bits (124), Expect = 8e-06
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 21/192 (10%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD---DQPVDESSRCHLGKEER 248
N P F + + R P P + W +D D P R H+ E+
Sbjct: 600 NMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDD 659
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENL--QAILSD 306
F +D++ +E D + C A N G + L ++ + P FL L + +
Sbjct: 660 VFFIVDVK-IE--DIGVYSCTAQNSAGSISANATLTVL-----ETPSFLRPLLDRTVTKG 711
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------DGTCS-LGTYTCEAS 359
E AV L+C G P P L W KD L + H +G D S G YTCE S
Sbjct: 712 ETAV-LQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMS 770
Query: 360 NCMGVAASSASL 371
N +G + L
Sbjct: 771 NTLGTERGNVRL 782
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 15/130 (11%)
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-N 311
L ++ +EF + +++CV N FG S S KL + P F + + GA+
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSY-SVKAKLTVNM---LPSFTKTPMDLTIRAGAMAR 621
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHR--IISGQDGTC--------SLGTYTCEASNC 361
LEC +G P P + W KDG P R + +D +G Y+C A N
Sbjct: 622 LECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNS 681
Query: 362 MGVAASSASL 371
G +++A+L
Sbjct: 682 AGSISANATL 691
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 54.0 bits (124), Expect = 8e-06
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 21/192 (10%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD---DQPVDESSRCHLGKEER 248
N P F + + R P P + W +D D P R H+ E+
Sbjct: 540 NMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDD 599
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENL--QAILSD 306
F +D++ +E D + C A N G + L ++ + P FL L + +
Sbjct: 600 VFFIVDVK-IE--DIGVYSCTAQNSAGSISANATLTVL-----ETPSFLRPLLDRTVTKG 651
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------DGTCS-LGTYTCEAS 359
E AV L+C G P P L W KD L + H +G D S G YTCE S
Sbjct: 652 ETAV-LQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMS 710
Query: 360 NCMGVAASSASL 371
N +G + L
Sbjct: 711 NTLGTERGNVRL 722
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 15/130 (11%)
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-N 311
L ++ +EF + +++CV N FG S S KL + P F + + GA+
Sbjct: 506 LRLREVEFASEGKYQCVISNHFGSSY-SVKAKLTVNM---LPSFTKTPMDLTIRAGAMAR 561
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHR--IISGQDGTC--------SLGTYTCEASNC 361
LEC +G P P + W KDG P R + +D +G Y+C A N
Sbjct: 562 LECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNS 621
Query: 362 MGVAASSASL 371
G +++A+L
Sbjct: 622 AGSISANATL 631
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 54.0 bits (124), Expect = 8e-06
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 21/192 (10%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD---DQPVDESSRCHLGKEER 248
N P F + + R P P + W +D D P R H+ E+
Sbjct: 600 NMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDD 659
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENL--QAILSD 306
F +D++ +E D + C A N G + L ++ + P FL L + +
Sbjct: 660 VFFIVDVK-IE--DIGVYSCTAQNSAGSISANATLTVL-----ETPSFLRPLLDRTVTKG 711
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------DGTCS-LGTYTCEAS 359
E AV L+C G P P L W KD L + H +G D S G YTCE S
Sbjct: 712 ETAV-LQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMS 770
Query: 360 NCMGVAASSASL 371
N +G + L
Sbjct: 771 NTLGTERGNVRL 782
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 15/130 (11%)
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-N 311
L ++ +EF + +++CV N FG S S KL + P F + + GA+
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSY-SVKAKLTVNM---LPSFTKTPMDLTIRAGAMAR 621
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHR--IISGQDGTC--------SLGTYTCEASNC 361
LEC +G P P + W KDG P R + +D +G Y+C A N
Sbjct: 622 LECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNS 681
Query: 362 MGVAASSASL 371
G +++A+L
Sbjct: 682 AGSISANATL 691
>AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open reading
frame 9 protein.
Length = 1263
Score = 54.0 bits (124), Expect = 8e-06
Identities = 73/310 (23%), Positives = 123/310 (39%), Gaps = 53/310 (17%)
Query: 105 QAVLTEEGLVS--FECKVVGFPTPVLSWFKDGQE--------LKPGDVYQLTG--TNSLG 152
Q V G +S C+ +G P P +SW ++G+E L+P D Q+ +G
Sbjct: 688 QTVALASGTLSVLLHCEAIGHPRPTISWARNGEEVQFSDRILLQPDDSLQILAPVEADVG 747
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
Y C A N +G S S +T+ L + ++ + + + V +++
Sbjct: 748 FYTCNATNALGYDSVSIAVTLAG--KPLVKTSRMTVINTEKPAVTVDIGSTIKTVQGVNV 805
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
+VA PE + W+R+ + H G L + + DQ + C A N
Sbjct: 806 TINCQVAGVPEAEVTWFRNKSKLGSPHHLHEGS-------LLLTNVSSSDQGLYSCRAAN 858
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG---------------------AVN 311
G+ S L ++ P + P LE+++A+L+ G +
Sbjct: 859 LHGELTESTQLLILDPP--QVPTQLEDIRALLAATGPNLPSVLTSPLGTQLVLDPGNSAL 916
Query: 312 LECKVIGVPQPVLKWYKDGEEL--KPGDIHRII-SGQD------GTCSLGTYTCEASNCM 362
L C + G P P + W+ G+ + G H I+ +GQ S G ++C A N
Sbjct: 917 LGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLSGGSQGEFSCLAQNEA 976
Query: 363 GVAASSASLL 372
GV ASL+
Sbjct: 977 GVLMQKASLV 986
Score = 34.3 bits (75), Expect = 7.0
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 13/84 (15%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQE-----------LKPGDVYQLTGTN--SL 151
Q VL C + G P P ++WF GQ L G + Q+ + S
Sbjct: 906 QLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLSGGSQ 965
Query: 152 GSYCCIAKNCMGQASSSAELTVED 175
G + C+A+N G A L ++D
Sbjct: 966 GEFSCLAQNEAGVLMQKASLVIQD 989
>AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open reading
frame 9 protein.
Length = 1263
Score = 54.0 bits (124), Expect = 8e-06
Identities = 73/310 (23%), Positives = 123/310 (39%), Gaps = 53/310 (17%)
Query: 105 QAVLTEEGLVS--FECKVVGFPTPVLSWFKDGQE--------LKPGDVYQLTG--TNSLG 152
Q V G +S C+ +G P P +SW ++G+E L+P D Q+ +G
Sbjct: 688 QTVALASGTLSVLLHCEAIGHPRPTISWARNGEEVQFSDRILLQPDDSLQILAPVEADVG 747
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
Y C A N +G S S +T+ L + ++ + + + V +++
Sbjct: 748 FYTCNATNALGYDSVSIAVTLAG--KPLVKTSRMTVINTEKPAVTVDIGSTIKTVQGVNV 805
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
+VA PE + W+R+ + H G L + + DQ + C A N
Sbjct: 806 TINCQVAGVPEAEVTWFRNKSKLGSPHHLHEGS-------LLLTNVSSSDQGLYSCRAAN 858
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG---------------------AVN 311
G+ S L ++ P + P LE+++A+L+ G +
Sbjct: 859 LHGELTESTQLLILDPP--QVPTQLEDIRALLAATGPNLPSVLTSPLGTQLVLDPGNSAL 916
Query: 312 LECKVIGVPQPVLKWYKDGEEL--KPGDIHRII-SGQD------GTCSLGTYTCEASNCM 362
L C + G P P + W+ G+ + G H I+ +GQ S G ++C A N
Sbjct: 917 LGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLSGGSQGEFSCLAQNEA 976
Query: 363 GVAASSASLL 372
GV ASL+
Sbjct: 977 GVLMQKASLV 986
Score = 34.3 bits (75), Expect = 7.0
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 13/84 (15%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQE-----------LKPGDVYQLTGTN--SL 151
Q VL C + G P P ++WF GQ L G + Q+ + S
Sbjct: 906 QLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLSGGSQ 965
Query: 152 GSYCCIAKNCMGQASSSAELTVED 175
G + C+A+N G A L ++D
Sbjct: 966 GEFSCLAQNEAGVLMQKASLVIQD 989
>AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open reading
frame 9 protein.
Length = 1263
Score = 54.0 bits (124), Expect = 8e-06
Identities = 73/310 (23%), Positives = 123/310 (39%), Gaps = 53/310 (17%)
Query: 105 QAVLTEEGLVS--FECKVVGFPTPVLSWFKDGQE--------LKPGDVYQLTG--TNSLG 152
Q V G +S C+ +G P P +SW ++G+E L+P D Q+ +G
Sbjct: 688 QTVALASGTLSVLLHCEAIGHPRPTISWARNGEEVQFSDRILLQPDDSLQILAPVEADVG 747
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
Y C A N +G S S +T+ L + ++ + + + V +++
Sbjct: 748 FYTCNATNALGYDSVSIAVTLAG--KPLVKTSRMTVINTEKPAVTVDIGSTIKTVQGVNV 805
Query: 213 RFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFN 272
+VA PE + W+R+ + H G L + + DQ + C A N
Sbjct: 806 TINCQVAGVPEAEVTWFRNKSKLGSPHHLHEGS-------LLLTNVSSSDQGLYSCRAAN 858
Query: 273 DFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG---------------------AVN 311
G+ S L ++ P + P LE+++A+L+ G +
Sbjct: 859 LHGELTESTQLLILDPP--QVPTQLEDIRALLAATGPNLPSVLTSPLGTQLVLDPGNSAL 916
Query: 312 LECKVIGVPQPVLKWYKDGEEL--KPGDIHRII-SGQD------GTCSLGTYTCEASNCM 362
L C + G P P + W+ G+ + G H I+ +GQ S G ++C A N
Sbjct: 917 LGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLSGGSQGEFSCLAQNEA 976
Query: 363 GVAASSASLL 372
GV ASL+
Sbjct: 977 GVLMQKASLV 986
Score = 34.3 bits (75), Expect = 7.0
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 13/84 (15%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQE-----------LKPGDVYQLTGTN--SL 151
Q VL C + G P P ++WF GQ L G + Q+ + S
Sbjct: 906 QLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLSGGSQ 965
Query: 152 GSYCCIAKNCMGQASSSAELTVED 175
G + C+A+N G A L ++D
Sbjct: 966 GEFSCLAQNEAGVLMQKASLVIQD 989
>AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens
cDNA FLJ90440 fis, clone NT2RP3000921, weakly similar to
TUMOR SUPPRESSOR PROTEIN DCC PRECURSOR. ).
Length = 697
Score = 54.0 bits (124), Expect = 8e-06
Identities = 52/192 (27%), Positives = 74/192 (38%), Gaps = 21/192 (10%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRD---DQPVDESSRCHLGKEER 248
N P F + + R P P + W +D D P R H+ E+
Sbjct: 178 NMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDD 237
Query: 249 GVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENL--QAILSD 306
F +D++ +E D + C A N G + L ++ + P FL L + +
Sbjct: 238 VFFIVDVK-IE--DIGVYSCTAQNSAGSISANATLTVL-----ETPSFLRPLLDRTVTKG 289
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQ------DGTCS-LGTYTCEAS 359
E AV L+C G P P L W KD L + H +G D S G YTCE S
Sbjct: 290 ETAV-LQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMS 348
Query: 360 NCMGVAASSASL 371
N +G + L
Sbjct: 349 NTLGTERGNVRL 360
Score = 45.6 bits (103), Expect = 0.003
Identities = 37/130 (28%), Positives = 58/130 (44%), Gaps = 15/130 (11%)
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAV-N 311
L ++ +EF + +++CV N FG S S KL + P F + + GA+
Sbjct: 144 LRLREVEFASEGKYQCVISNHFGSSY-SVKAKLTVNM---LPSFTKTPMDLTIRAGAMAR 199
Query: 312 LECKVIGVPQPVLKWYKDGEELKPGDIHR--IISGQDGTC--------SLGTYTCEASNC 361
LEC +G P P + W KDG P R + +D +G Y+C A N
Sbjct: 200 LECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNS 259
Query: 362 MGVAASSASL 371
G +++A+L
Sbjct: 260 AGSISANATL 269
>AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein.
Length = 507
Score = 54.0 bits (124), Expect = 8e-06
Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 10/88 (11%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPG-DIHRIISGQDGTCSL 351
PRF + L++ EG V L+C V+G+P P ++WY +G+EL+ DIH + +G + ++
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 352 --------GTYTCEASNCMGVAASSASL 371
G Y+C ASN G ++SA +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEI 356
Score = 51.6 bits (118), Expect = 4e-05
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 15/126 (11%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQLTG 147
PRF + L++ EG V +C VVG P P + W+ +G+EL + G+++ LT
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 148 TNSL----GSYCCIAKNCMGQASSSAELTVEDIQNQLNE-EEKLQLFSKNQAPKFVHGLK 202
+ G Y C A N G S+SAE+ +E + + +E + + ++ Q P V
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 388
Query: 203 SVEAKI 208
+ A I
Sbjct: 389 TTSAVI 394
Score = 38.7 bits (86), Expect = 0.33
Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 98 PRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDG 134
P F + LQ + EG LV FEC+V G P+P + W+++G
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREG 472
Score = 38.3 bits (85), Expect = 0.43
Identities = 18/50 (36%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
P F + LQ + + EG V EC+V G P P ++WY++G ++ RI+
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRIL 484
>AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecule
NB-3 protein.
Length = 1028
Score = 54.0 bits (124), Expect = 8e-06
Identities = 64/285 (22%), Positives = 117/285 (41%), Gaps = 32/285 (11%)
Query: 99 RFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFK-DGQELKPGDVYQLTGTNSLGSYCCI 157
RF E +QA ++ V EC +G P P +SW + DG L PG V S
Sbjct: 232 RFPETIQAA--KDSSVKLECFALGNPVPDISWRRLDGSPL-PGKVKY-----SKSQAILE 283
Query: 158 AKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIK 217
N + E +++ + + +L ++ P++ +++ I + + K
Sbjct: 284 IPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAP---PEWEQKIQNTHLSIYDNLLWECK 340
Query: 218 VAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+ P P W ++ + ++ R + E G L I L D ++C A N +
Sbjct: 341 ASGKPNPWYTWLKNGERLNPEERIQI---ENGT--LIITMLNVSDSGVYQCAAENKYQII 395
Query: 278 VTSCFLKLII--PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ L+++ P K P ++ + G + + CK P+ + W + E L+
Sbjct: 396 YANAELRVLASAPDFSKSP---VKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQ 452
Query: 336 GDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASLL 372
RI +DG+ + G+YTC A+N G A ++ SL+
Sbjct: 453 SK--RIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLI 495
Score = 39.9 bits (89), Expect = 0.14
Identities = 39/182 (21%), Positives = 74/182 (40%), Gaps = 11/182 (6%)
Query: 95 YRKPRFMENLQAV-LTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGS 153
Y P + + +Q L+ + +ECK G P P +W K+G+ L P + Q+ + +
Sbjct: 315 YAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIIT 374
Query: 154 YCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFR 213
++ + + Q ++ + + +L FSK+ K KS ++
Sbjct: 375 MLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKK-----KSF-VQVGGDIV 428
Query: 214 FTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND 273
K P ++ W R + + +S R L ++ L I + D + C+A N
Sbjct: 429 IGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGS----LKIYNITRSDAGSYTCIATNQ 484
Query: 274 FG 275
FG
Sbjct: 485 FG 486
>BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein.
Length = 294
Score = 53.6 bits (123), Expect = 1e-05
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 17/188 (9%)
Query: 194 APKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERG--VF 251
AP ++ K++ E R + P+P++ W + +P+ +S+ + +E G +
Sbjct: 11 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPL-QSAPPNPNREVAGDTII 69
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAV 310
F D Q +A ++C N+ G + + F+ ++ +P PR + ++ IL +
Sbjct: 70 FRDTQ---ISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN-QLIRVILYNR--T 123
Query: 311 NLECKVIGVPQPVLKWYKDGE--ELKPGDIHRIISGQDGTCSL-----GTYTCEASNCMG 363
L+C G P P L+W+K+G+ L G+ H +G + G YTC A+N +G
Sbjct: 124 RLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILG 183
Query: 364 VAASSASL 371
A + L
Sbjct: 184 KAENQVRL 191
Score = 44.4 bits (100), Expect = 0.007
Identities = 44/181 (24%), Positives = 73/181 (40%), Gaps = 32/181 (17%)
Query: 117 ECKVVGFPTPVLSWFKDGQELK-PGDVYQLTGTNSL----------GSYCCIAKNCMGQA 165
+C G P P L WFK+GQ G Y + SL G Y C+A N +G+A
Sbjct: 126 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 185
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
+ L V+D ++ + Q+ + + K D + T+
Sbjct: 186 ENQVRLEVKD-PTRIYRMPEDQVARRGTTVQL-----ECRVKHDPSLKLTVS-------- 231
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL 285
W +DD+P+ +R + KE+ L I + DQ + CVA + Q + +L +
Sbjct: 232 --WLKDDEPLYIGNR--MKKEDDS---LTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 284
Query: 286 I 286
+
Sbjct: 285 L 285
Score = 41.1 bits (92), Expect = 0.061
Identities = 66/264 (25%), Positives = 110/264 (41%), Gaps = 48/264 (18%)
Query: 118 CKVVGFPTPVLSWFKDGQELK----------PGD--VYQLTGTNSLGSYCCIAKNCMGQA 165
C+ G P P + W +G+ L+ GD +++ T +S Y C N G
Sbjct: 33 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 92
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
++A ++V D+ ++ L +NQ + + ++D PF + P P+
Sbjct: 93 LANAFVSVLDVPPRM-------LSPRNQ---LIRVILYNRTRLDCPFFGS------PIPT 136
Query: 226 LLWYRDDQPVD-ESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK 284
L W+++ Q + + H+ E G L+I+ + DQ + CVA N G++ L+
Sbjct: 137 LRWFKNGQGSNLDGGNYHV--YENG--SLEIKMIRKEDQGIYTCVATNILGKAENQVRLE 192
Query: 285 LIIP-RHYKKPRFLENLQAILSDEGAVNLECKVIGVP--QPVLKWYKD------GEELKP 335
+ P R Y+ P + V LEC+V P + + W KD G +K
Sbjct: 193 VKDPTRIYRMPE-----DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK 247
Query: 336 GDIHRIISGQDGTCSLGTYTCEAS 359
D I G G+YTC AS
Sbjct: 248 EDDSLTIFGV-AERDQGSYTCVAS 270
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 53.2 bits (122), Expect = 1e-05
Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 14/158 (8%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W ++++ +D S L G L+I + D + C+A N G
Sbjct: 276 PTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTEDDAGTYFCIADN--GNETIEA 331
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHR 340
+L + +P FL+ I + E + EC+V G P P +KW K+G+ + P D +
Sbjct: 332 QAELTVQA---QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFK 388
Query: 341 IISGQD----GTCSL--GTYTCEASNCMGVAASSASLL 372
I+ + G G Y C A N +G A + A L+
Sbjct: 389 IVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLI 426
Score = 52.8 bits (121), Expect = 2e-05
Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 11/88 (12%)
Query: 97 KPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F++ + E + + FEC+V G PTP + W K+G + P D +++ ++L
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLG 399
Query: 152 ------GSYCCIAKNCMGQASSSAELTV 173
G Y CIA+N +G A + A+L +
Sbjct: 400 LVKSDEGFYQCIAENDVGNAQAGAQLII 427
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 53.2 bits (122), Expect = 1e-05
Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 14/158 (8%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W ++++ +D S L G L+I + D + C+A N G
Sbjct: 276 PTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTEDDAGTYFCIADN--GNETIEA 331
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHR 340
+L + +P FL+ I + E + EC+V G P P +KW K+G+ + P D +
Sbjct: 332 QAELTVQA---QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFK 388
Query: 341 IISGQD----GTCSL--GTYTCEASNCMGVAASSASLL 372
I+ + G G Y C A N +G A + A L+
Sbjct: 389 IVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLI 426
Score = 52.8 bits (121), Expect = 2e-05
Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 11/88 (12%)
Query: 97 KPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F++ + E + + FEC+V G PTP + W K+G + P D +++ ++L
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLG 399
Query: 152 ------GSYCCIAKNCMGQASSSAELTV 173
G Y CIA+N +G A + A+L +
Sbjct: 400 LVKSDEGFYQCIAENDVGNAQAGAQLII 427
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 53.2 bits (122), Expect = 1e-05
Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 14/158 (8%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W ++++ +D S L G L+I + D + C+A N G
Sbjct: 276 PTPTIKWMKNEEALDTESSERLVLLAGGS--LEISDVTEDDAGTYFCIADN--GNETIEA 331
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHR 340
+L + +P FL+ I + E + EC+V G P P +KW K+G+ + P D +
Sbjct: 332 QAELTVQA---QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFK 388
Query: 341 IISGQD----GTCSL--GTYTCEASNCMGVAASSASLL 372
I+ + G G Y C A N +G A + A L+
Sbjct: 389 IVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLI 426
Score = 52.8 bits (121), Expect = 2e-05
Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 11/88 (12%)
Query: 97 KPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F++ + E + + FEC+V G PTP + W K+G + P D +++ ++L
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLG 399
Query: 152 ------GSYCCIAKNCMGQASSSAELTV 173
G Y CIA+N +G A + A+L +
Sbjct: 400 LVKSDEGFYQCIAENDVGNAQAGAQLII 427
>AJ314898-1|CAC85746.1| 646|Homo sapiens obscurin protein.
Length = 646
Score = 52.8 bits (121), Expect = 2e-05
Identities = 61/258 (23%), Positives = 102/258 (39%), Gaps = 27/258 (10%)
Query: 112 GLVSFECKVVGFPTPVLSWFKDGQEL-KPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAE 170
G FEC+ V W+KDG EL G+ + + + + S
Sbjct: 393 GPAQFECETSEAHVHV-HWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCR 451
Query: 171 LTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYR 230
+ + + +L E +F+K Q + V+A++ + +VA + + WY+
Sbjct: 452 VGEDSVDFRLRVSEPKAVFAKEQP-----ACREVQAEVGASATLSCEVA-QDQMEVTWYK 505
Query: 231 DDQPVDESSRCHLGKEERGVFF-LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR 289
D + + SS+ H+ E G L +Q + D E+ C A GQ V+ +L P+
Sbjct: 506 DGKKLSSSSKVHV--EAVGCMRRLVVQQVGQADSGEYSCEAR---GQRVS---FRLDEPK 557
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP---------GDIHR 340
L + + L C+V Q + WYKDG++L G R
Sbjct: 558 VVFAKEQLARRKLQAEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKVCMEATGCTRR 616
Query: 341 IISGQDGTCSLGTYTCEA 358
++ Q G G Y+CEA
Sbjct: 617 LVVQQAGQADAGEYSCEA 634
Score = 37.5 bits (83), Expect = 0.75
Identities = 63/292 (21%), Positives = 110/292 (37%), Gaps = 32/292 (10%)
Query: 80 SIKMIHNSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP 139
SI+M + P + N + A L EE + E + ++W KDG+ L P
Sbjct: 272 SIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAE---LSDQAAAVTWLKDGRTLSP 328
Query: 140 GDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED--IQNQLNEEEKLQLFSKNQAPKF 197
G Y++ S G + ++ + E I QL+ + + K+ A
Sbjct: 329 GPKYEVQA--SAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAG-- 384
Query: 198 VHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQA 257
V+A P +F + + + WY+D + S L ++ L
Sbjct: 385 ----SCVDAVAGGPAQFECETS-EAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAAT 439
Query: 258 LEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPR--HYKKPRFLENLQAILSDEGAVNLECK 315
+ D+ + C G+ L++ P+ K+ +QA + + L C+
Sbjct: 440 VTRQDEGTYSC----RVGEDSVDFRLRVSEPKAVFAKEQPACREVQAEVG--ASATLSCE 493
Query: 316 VIGVPQPVLKWYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCEA 358
V Q + WYKDG++L G + R++ Q G G Y+CEA
Sbjct: 494 V-AQDQMEVTWYKDGKKLSSSSKVHVEAVGCMRRLVVQQVGQADSGEYSCEA 544
>AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 variant
protein.
Length = 1130
Score = 52.8 bits (121), Expect = 2e-05
Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 11/88 (12%)
Query: 97 KPRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSL---- 151
+P F++ + E + + FEC+V G PTP + W K+G + P D +++ ++L
Sbjct: 16 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLG 75
Query: 152 ------GSYCCIAKNCMGQASSSAELTV 173
G Y CIA+N +G A + A+L +
Sbjct: 76 LVKSDEGFYQCIAENDVGNAQAGAQLII 103
Score = 45.2 bits (102), Expect = 0.004
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 7/87 (8%)
Query: 293 KPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQD----G 347
+P FL+ I + E + EC+V G P P +KW K+G+ + P D +I+ + G
Sbjct: 16 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLG 75
Query: 348 TCSL--GTYTCEASNCMGVAASSASLL 372
G Y C A N +G A + A L+
Sbjct: 76 LVKSDEGFYQCIAENDVGNAQAGAQLI 102
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 52.4 bits (120), Expect = 2e-05
Identities = 60/246 (24%), Positives = 98/246 (39%), Gaps = 22/246 (8%)
Query: 91 VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNS 150
VP P+ N A EE ++F C+ G P P +SWF++G+ ++ + Y L G+N+
Sbjct: 207 VPPAISMPQKSFNATAERGEE--MTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNT 264
Query: 151 LGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE 210
+N + +S V N+ E+EK Q F + + LK+ +
Sbjct: 265 E----LTVRNII---NSDGGPYVCRATNKAGEDEK-QAFLQVFVQPHIIQLKNETTYENG 316
Query: 211 PFRFTIKVAIPPEPSLLWYR--DDQPVDESSRCHLG----KEERGVFFLDIQALEFLDQA 264
P P + W R D E + G K + G L I+ ++
Sbjct: 317 QVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSG 376
Query: 265 EWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPV 323
+ C A + G S +L + Y P+F+ N S EG +N+ C V P
Sbjct: 377 RYDCEAASRIGGHQKSMYLDI----EY-APKFISNQTIYYSWEGNPINISCDVKSNPPAS 431
Query: 324 LKWYKD 329
+ W +D
Sbjct: 432 IHWRRD 437
>AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein
protein.
Length = 1232
Score = 52.4 bits (120), Expect = 2e-05
Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 3/124 (2%)
Query: 162 MGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIP 221
+ + S + T E + E + + S P V GL+ D +F +K
Sbjct: 630 ISETKKSDQKTTESTVTRKTEPKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGE 687
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P+ +W +D + + + + L E++G FFL+I + D + C N G +SC
Sbjct: 688 PRPTAIWTKDGKAITQGGKYKL-SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSC 746
Query: 282 FLKL 285
L +
Sbjct: 747 KLTI 750
Score = 48.8 bits (111), Expect = 3e-04
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 14/96 (14%)
Query: 97 KPRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL---------- 145
KP + LQ ++ + + F K G P P W KDG+ + G Y+L
Sbjct: 660 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 719
Query: 146 ---TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQN 178
T T+ G Y C KN G SSS +LT++ I++
Sbjct: 720 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 755
Score = 40.7 bits (91), Expect = 0.081
Identities = 96/465 (20%), Positives = 175/465 (37%), Gaps = 37/465 (7%)
Query: 2500 LEVMAPH-LTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVEQDL 2558
L A H +T K K EI D V++++ E+ ++QKA V E+ +
Sbjct: 410 LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 469
Query: 2559 NSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKITDNL 2618
SP + K+P V + + + K + E K + +L
Sbjct: 470 TSPPRV------KSPEPRVKSPEAVKSPKRVKSPEPSHPK--AVSPTETKPTPTEKVQHL 521
Query: 2619 FSIEAAQSIEVKEDFSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPTNINLLVDD 2678
+ A I +K+ + +T V+ESS +R E D L ++
Sbjct: 522 -PVSAPPKIT-----QFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDG-----KKLKEN 570
Query: 2679 SLLEIDKAVKSTEALK--NIPQRDLAENEQQLGEDTTGSKQKVVELPDTIDDVSQDMI-V 2735
+ + T LK N+ + D E+ ++ + SK + + + + + +
Sbjct: 571 GHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKI 630
Query: 2736 EHLPTSEVKLLEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVD--LVKIAGEPEI 2793
S+ K E + E E + S V V +T + SV VK GEP
Sbjct: 631 SETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 690
Query: 2794 KSKLVEELQTIADSKSQKMIE-------ESTTRETVESPLITTGKTTETPNDITSMNVGE 2846
+ ++ + I K+ E E +T +S L T + +S +
Sbjct: 691 TAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 750
Query: 2847 TEKQRKESITELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEV 2906
+ E+ QK+S+ T + V V +EI + L S+EIK ++ + K L E
Sbjct: 751 KAIKDTEAQKVSTQKTSEITPQKKAV--VQEEISQKALRSEEIKMSEAKSQEKLALKEEA 808
Query: 2907 NLPLVTGHETIQTLNSNLENEMC--ESLKIEQAVSAETTESTVES 2949
+ L++ E ++ ++LE + E K QA T + +++
Sbjct: 809 SKVLIS-EEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKA 852
Score = 40.3 bits (90), Expect = 0.11
Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 192 NQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVF 251
+ AP F+ +S + FT +++ P P + W++++ P+ SS + + R V+
Sbjct: 940 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR-SRNVY 998
Query: 252 FLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
L+I+ D ++ A N GQ + L +++P
Sbjct: 999 SLEIRNASVSDSGKYTIKAKNFRGQCSATASL-MVLP 1034
Score = 39.5 bits (88), Expect = 0.19
Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 10/89 (11%)
Query: 293 KPRFLENLQ-AILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDG---- 347
KP + LQ +S + K G P+P W KDG+ + G +++ + G
Sbjct: 660 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 719
Query: 348 -----TCSLGTYTCEASNCMGVAASSASL 371
T G YTC N G +SS L
Sbjct: 720 IHKTDTSDSGLYTCTVKNSAGSVSSSCKL 748
Score = 38.7 bits (86), Expect = 0.33
Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 166 SSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPS 225
S A L + + E Q F+ + AP+ ++S + RF + V P
Sbjct: 154 SMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAE 213
Query: 226 LLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQS 277
+ WY + + ESS+ H GV L+I D ++ V N G++
Sbjct: 214 VKWYHNGVELQESSKIHY-TNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEA 264
Score = 37.1 bits (82), Expect = 1.00
Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 14/104 (13%)
Query: 98 PRFMENLQAVLTEEGL-VSFECKVVGFPTPVLSWFKDGQEL---------KPGDVYQL-- 145
P F+ ++ EG V F C++ G P+P + WFK+ + + +VY L
Sbjct: 943 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 1002
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQ 187
+ G Y AKN GQ S++A L V + + + E L+
Sbjct: 1003 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLR 1046
Score = 35.5 bits (78), Expect = 3.0
Identities = 23/97 (23%), Positives = 39/97 (40%)
Query: 184 EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHL 243
EK+Q + PK LK+ +K ++ ++ + WY+D + + E+
Sbjct: 516 EKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQF 575
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTS 280
G + L I L DQ E C + G S T+
Sbjct: 576 HYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTN 612
Score = 34.7 bits (76), Expect = 5.3
Identities = 36/181 (19%), Positives = 69/181 (38%), Gaps = 14/181 (7%)
Query: 203 SVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLD 262
S + I+E R +K I W + + S G L I+ D
Sbjct: 854 STQMSINEGQRLVLKANIAGATDAKWVLNGVELTNSEEYRYGVSGSDQT-LTIKQASHRD 912
Query: 263 QAEWKCVAFNDFGQSVTSCFLKLIIPRHYKK-PRFLENLQAILSDEGA-VNLECKVIGVP 320
+ C++ G + C L + + P F+ ++ +EG V C++ G P
Sbjct: 913 EGILTCISKTKEG--IVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEP 970
Query: 321 QPVLKWYKDGEEL---------KPGDIHRIISGQDGTCSLGTYTCEASNCMGVAASSASL 371
P ++W+K+ + + +++ + G YT +A N G +++ASL
Sbjct: 971 SPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 1030
Query: 372 L 372
+
Sbjct: 1031 M 1031
>AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kinase
isoform 4 protein.
Length = 560
Score = 52.0 bits (119), Expect = 3e-05
Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 12/106 (11%)
Query: 276 QSVTSCFLKLIIP-RHYKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEEL 333
+ V+ FL+ + + + KP F + ++ + EG A +CK+ G P P + W+KD + +
Sbjct: 436 EDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 495
Query: 334 KPGDIHRIISGQDGTCSL----------GTYTCEASNCMGVAASSA 369
+ +I +DG CSL YTC+A N +G A +A
Sbjct: 496 RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 541
Score = 50.0 bits (114), Expect = 1e-04
Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 15/108 (13%)
Query: 93 KNYRKPRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL----TG 147
K + KP F + ++ + EG + F+CK+ G+P P + WFKD Q ++ +Q+ G
Sbjct: 450 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 509
Query: 148 TNSL----------GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEK 185
SL Y C A N +G+A+ +AE VE ++ E E+
Sbjct: 510 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGEGEE 557
Score = 46.8 bits (106), Expect = 0.001
Identities = 24/83 (28%), Positives = 41/83 (49%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLD 254
P F ++ +E RF K+ P+P ++W++DDQ + ES + +E G L
Sbjct: 455 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 514
Query: 255 IQALEFLDQAEWKCVAFNDFGQS 277
I + D A++ C A N G++
Sbjct: 515 ISDVCGDDDAKYTCKAVNSLGEA 537
>AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific titin
protein.
Length = 926
Score = 52.0 bits (119), Expect = 3e-05
Identities = 47/211 (22%), Positives = 95/211 (45%), Gaps = 36/211 (17%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS--RCHLGKEERGVFF 252
P F+ + + + + + ++ V P+P + W+ + + S+ + ++ +
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL--------------IIPRHYKK----- 293
L LE D+ E+ C+A ND+G+++ S +LK+ + + +K
Sbjct: 109 L-FTKLE--DEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC 165
Query: 294 -PRFLENLQAILSDEGAVNL-ECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL 351
P FL+ L+ I +G + E V+G P P + W+K+ ++L + II +G+ +
Sbjct: 166 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 225
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G Y C+A N +G + +A LL
Sbjct: 226 IVNDPQREDSGLYICKAENMLGESTCAAELL 256
Score = 45.6 bits (103), Expect = 0.003
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 15/91 (16%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL------TGT-- 148
P F++ L+ + +GL + FE VVG P P ++WFK+ ++L Y + +GT
Sbjct: 167 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 226
Query: 149 ------NSLGSYCCIAKNCMGQASSSAELTV 173
G Y C A+N +G+++ +AEL V
Sbjct: 227 VNDPQREDSGLYICKAENMLGESTCAAELLV 257
Score = 45.2 bits (102), Expect = 0.004
Identities = 47/211 (22%), Positives = 85/211 (40%), Gaps = 23/211 (10%)
Query: 98 PRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQL-- 145
P F++ + A ++ + + V+G P P + WF +G L P GD + L
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTV-------EDIQNQLNEEEKLQLFSKNQAPK 196
T G Y C+A N G+ SA L + +D + + + L+ P
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
F+ LK + P F V P P++ W+++++ + S + G +
Sbjct: 169 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + C A N G+S +C +L++
Sbjct: 229 DPQREDSGLYICKAENMLGES--TCAAELLV 257
Score = 35.5 bits (78), Expect = 3.0
Identities = 81/377 (21%), Positives = 157/377 (41%), Gaps = 36/377 (9%)
Query: 2695 NIPQRD-----LAENEQQLGEDTTGSKQKVV-ELPDTIDDVSQDMIVEHLPTSEVKL-LE 2747
N PQR+ + + E LGE T ++ V+ E D D + P + L+
Sbjct: 228 NDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLK 287
Query: 2748 GQLLAA--EENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKSKLVEELQTIA 2805
G + A E ++ +K +++ TE ++ + IA E+ S+L Q +
Sbjct: 288 GPAVEALDSEQEIATFVKDTILKAALITE---ENQQLSYEHIAKANELSSQLPLGAQELQ 344
Query: 2806 DSKSQKMIEESTTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESITELNQKSSDF 2865
Q + +TRE L G P S N+ Q +++ ++ +
Sbjct: 345 SILEQDKLTPESTREF----LCINGSIHFQPLKEPSPNLQLQIVQSQKTFSKEGILMPEE 400
Query: 2866 TKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHETIQTLNSNLE 2925
++Q+++SD +++I + ++I + L E N P + + + +++
Sbjct: 401 PETQAVLSD-TEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSSIEPPMHSYLTSVA 459
Query: 2926 NEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKKDQAESSNSQTA--ENIVR 2983
E+ S K E+ VS E V Q+ ++ L ++S+ L + ES S +
Sbjct: 460 EEVL-SXK-EKTVSDTNREQRVTLQKQEAQSAL-ILSQSLAEGHVESLQSPDVMISQVNY 516
Query: 2984 EIVVTSEITALETLGL------PLERSGNDGDL-VEL-------LSIETKQITVEPRATT 3029
E +V SE + E + PLE +G D + +E L++E KQ+ ++ +
Sbjct: 517 EPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEKQVLLKEEHSD 576
Query: 3030 YEVVAEQQVVPSGQQPV 3046
V+ Q++ S ++PV
Sbjct: 577 NVVMPPDQIIESKREPV 593
>AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein.
Length = 1019
Score = 52.0 bits (119), Expect = 3e-05
Identities = 47/211 (22%), Positives = 95/211 (45%), Gaps = 36/211 (17%)
Query: 195 PKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESS--RCHLGKEERGVFF 252
P F+ + + + + + ++ V P+P + W+ + + S+ + ++ +
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 253 LDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKL--------------IIPRHYKK----- 293
L LE D+ E+ C+A ND+G+++ S +LK+ + + +K
Sbjct: 109 L-FTKLE--DEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPC 165
Query: 294 -PRFLENLQAILSDEGAVNL-ECKVIGVPQPVLKWYKDGEELKPGDIHRIISGQDGTCSL 351
P FL+ L+ I +G + E V+G P P + W+K+ ++L + II +G+ +
Sbjct: 166 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTF 225
Query: 352 ----------GTYTCEASNCMGVAASSASLL 372
G Y C+A N +G + +A LL
Sbjct: 226 IVNDPQREDSGLYICKAENMLGESTCAAELL 256
Score = 49.6 bits (113), Expect = 2e-04
Identities = 42/156 (26%), Positives = 68/156 (43%), Gaps = 17/156 (10%)
Query: 228 WYRDDQ--PVDESSRCHLGKEERGVFFLDIQALEFLD-QAEWKCVAFNDFGQSVTSCFLK 284
WY +++ P DE +C +++ + L I + D Q E+ C A ND G++ TS L
Sbjct: 866 WYFENKLVPSDEKFKC---LQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 922
Query: 285 LIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG 344
++ R +E L+ L C++ P +W+K G E+ D I S
Sbjct: 923 VVKRAAPVIKRKIEPLEVALGH--LAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSS 980
Query: 345 ---------QDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC+ASN G + +A+L
Sbjct: 981 KYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 1016
Score = 46.0 bits (104), Expect = 0.002
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 19/136 (13%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G Y C A N G+ ++SA+LTV K AP ++ +E +
Sbjct: 902 GEYVCEALNDSGKTATSAKLTVV----------------KRAAPVIKRKIEPLEVALGHL 945
Query: 212 FRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAF 271
+FT ++ P W++ + + ES +C + + + + L+I + +D E+ C A
Sbjct: 946 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 1004
Query: 272 NDFGQSVTSCFLKLII 287
N++G SC L +
Sbjct: 1005 NEYGS--VSCTATLTV 1018
Score = 45.6 bits (103), Expect = 0.003
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 15/91 (16%)
Query: 98 PRFMENLQAVLTEEGLVS-FECKVVGFPTPVLSWFKDGQELKPGDVYQL------TGT-- 148
P F++ L+ + +GL + FE VVG P P ++WFK+ ++L Y + +GT
Sbjct: 167 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 226
Query: 149 ------NSLGSYCCIAKNCMGQASSSAELTV 173
G Y C A+N +G+++ +AEL V
Sbjct: 227 VNDPQREDSGLYICKAENMLGESTCAAELLV 257
Score = 45.2 bits (102), Expect = 0.004
Identities = 47/211 (22%), Positives = 85/211 (40%), Gaps = 23/211 (10%)
Query: 98 PRFMENLQ-AVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKP---------GDVYQL-- 145
P F++ + A ++ + + V+G P P + WF +G L P GD + L
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 146 --TGTNSLGSYCCIAKNCMGQASSSAELTV-------EDIQNQLNEEEKLQLFSKNQAPK 196
T G Y C+A N G+ SA L + +D + + + L+ P
Sbjct: 109 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 168
Query: 197 FVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQ 256
F+ LK + P F V P P++ W+++++ + S + G +
Sbjct: 169 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 228
Query: 257 ALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
+ D + C A N G+S +C +L++
Sbjct: 229 DPQREDSGLYICKAENMLGES--TCAAELLV 257
Score = 35.5 bits (78), Expect = 3.0
Identities = 81/377 (21%), Positives = 157/377 (41%), Gaps = 36/377 (9%)
Query: 2695 NIPQRD-----LAENEQQLGEDTTGSKQKVV-ELPDTIDDVSQDMIVEHLPTSEVKL-LE 2747
N PQR+ + + E LGE T ++ V+ E D D + P + L+
Sbjct: 228 NDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLK 287
Query: 2748 GQLLAA--EENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKSKLVEELQTIA 2805
G + A E ++ +K +++ TE ++ + IA E+ S+L Q +
Sbjct: 288 GPAVEALDSEQEIATFVKDTILKAALITE---ENQQLSYEHIAKANELSSQLPLGAQELQ 344
Query: 2806 DSKSQKMIEESTTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESITELNQKSSDF 2865
Q + +TRE L G P S N+ Q +++ ++ +
Sbjct: 345 SILEQDKLTPESTREF----LCINGSIHFQPLKEPSPNLQLQIVQSQKTFSKEGILMPEE 400
Query: 2866 TKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHETIQTLNSNLE 2925
++Q+++SD +++I + ++I + L E N P + + + +++
Sbjct: 401 PETQAVLSD-TEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSSIEPPMHSYLTSVA 459
Query: 2926 NEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKKDQAESSNSQTA--ENIVR 2983
E+ S K E+ VS E V Q+ ++ L ++S+ L + ES S +
Sbjct: 460 EEVL-SXK-EKTVSDTNREQRVTLQKQEAQSAL-ILSQSLAEGHVESLQSPDVMISQVNY 516
Query: 2984 EIVVTSEITALETLGL------PLERSGNDGDL-VEL-------LSIETKQITVEPRATT 3029
E +V SE + E + PLE +G D + +E L++E KQ+ ++ +
Sbjct: 517 EPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEKQVLLKEEHSD 576
Query: 3030 YEVVAEQQVVPSGQQPV 3046
V+ Q++ S ++PV
Sbjct: 577 NVVMPPDQIIESKREPV 593
>AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.
Length = 1250
Score = 51.6 bits (118), Expect = 4e-05
Identities = 66/283 (23%), Positives = 99/283 (34%), Gaps = 39/283 (13%)
Query: 110 EEGLVSFECKVVGFPTPVLSWFKDGQELK--------PGDVYQLTGT--NSLGSYCCIAK 159
E G FEC + G P P+++W KD L P V Q+ + G Y C+A
Sbjct: 156 ENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVAT 215
Query: 160 NCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVA 219
N Q S L + L ++ Q V ++ + +
Sbjct: 216 NSARQHFSQEALLSVAHRGSLAS-------TRGQDVVIVAAPENTTVVSGQSVVMECVAS 268
Query: 220 IPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVA----FNDFG 275
P P + W R D + LG+ L I + + C A DF
Sbjct: 269 ADPTPFVSWVRQDGKPISTDVIVLGRTN-----LLIANAQPWHSGVYVCRANKPRTRDFA 323
Query: 276 QSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKP 335
+ + L P + P L +A C+ G P+P L+W +G L+P
Sbjct: 324 TAAAELRV-LAAPAITQAPEALSRTRA-----STARFVCRASGEPRPALRWLHNGAPLRP 377
Query: 336 GDIHRIISG-------QDGTCSLGTYTCEASNCMGVAASSASL 371
++ G Q G G Y C A N G+A ++ASL
Sbjct: 378 NGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASL 420
Score = 39.1 bits (87), Expect = 0.25
Identities = 43/175 (24%), Positives = 72/175 (41%), Gaps = 12/175 (6%)
Query: 114 VSFECKVVGFPTPVLSWFK-DGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELT 172
V EC PTP +SW + DG+ + DV L TN L + + + ++ T
Sbjct: 261 VVMECVASADPTPFVSWVRQDGKPIST-DVIVLGRTNLLIANAQPWHSGVYVCRANKPRT 319
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDD 232
D E L + QAP+ + ++ A RF + + P P+L W +
Sbjct: 320 -RDFATAAAELRVLAAPAITQAPEALSRTRASTA------RFVCRASGEPRPALRWLHNG 372
Query: 233 QPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
P+ + R K + G L I + D ++CVA N G + + L +++
Sbjct: 373 APLRPNGRV---KVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVV 424
Score = 38.7 bits (86), Expect = 0.33
Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 11/76 (14%)
Query: 109 TEEGLVSFECKVVGFPTPVLSWFKDGQELKP-GDVYQLTGTNSL----------GSYCCI 157
T F C+ G P P L W +G L+P G V G SL G Y C+
Sbjct: 347 TRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCV 406
Query: 158 AKNCMGQASSSAELTV 173
A+N G A ++A L V
Sbjct: 407 AENSAGMACAAASLAV 422
>AK096458-1|BAC04796.1| 410|Homo sapiens protein ( Homo sapiens
cDNA FLJ39139 fis, clone NTONG2009229. ).
Length = 410
Score = 51.2 bits (117), Expect = 6e-05
Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 19/117 (16%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQEL----------K 138
P P+ +KPR E + E V EC+V G PTP + WF +G+EL +
Sbjct: 145 PAAPRFIQKPRSQE-----VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCE 199
Query: 139 PGDVYQL----TGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSK 191
GD++ L + G Y C+A N G ++SAE+ +E + ++ E L S+
Sbjct: 200 GGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSR 256
Score = 48.8 bits (111), Expect = 3e-04
Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 11/89 (12%)
Query: 294 PRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEEL----------KPGDIHRII 342
PRF++ ++ EG+ V LEC+V G P P ++W+ +G+EL + GD+H +I
Sbjct: 148 PRFIQKPRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 207
Query: 343 SGQDGTCSLGTYTCEASNCMGVAASSASL 371
+ G YTC A+N G +SA +
Sbjct: 208 IAEAFEDDTGRYTCLATNPSGSDTTSAEV 236
Score = 34.3 bits (75), Expect = 7.0
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 291 YKKPRFLENLQAILSDEG-AVNLECKVIGVPQPVLKWYKDGEELKPGDIHRII 342
Y P F + LQ EG V LEC+V G P +W++ G E++ RI+
Sbjct: 315 YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQDQWFRQGSEIQDSPDFRIL 367
>AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ90299 fis, clone NT2RP2000514, highly similar to
Homo sapiens roundabout 2 (robo2) mRNA. ).
Length = 570
Score = 51.2 bits (117), Expect = 6e-05
Identities = 60/238 (25%), Positives = 94/238 (39%), Gaps = 37/238 (15%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEP 211
G+Y CIA+N +G+ +SA LTV P+FV +
Sbjct: 6 GTYMCIAENRVGKMEASATLTVRA--------------RPVAPPQFVVRPRDQIVAQGRT 51
Query: 212 FRFTIKVAIPPEPSLLWYRD--------DQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
F + P+P++ W ++ +QP +SRC + L I ++ D
Sbjct: 52 VTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD----LTITNIQRSDA 107
Query: 264 AEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLEN-LQAILSDEGAVNLECKVIGVPQ 321
+ C A G + L++ + P L+ L+ +G L+CK G P
Sbjct: 108 GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL 167
Query: 322 PVLKWYKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
PV+ W K+G PG R + GT + GTYTC A++ G + SA L
Sbjct: 168 PVISWLKEGFTF-PGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVL 224
Score = 40.7 bits (91), Expect = 0.081
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 11/79 (13%)
Query: 108 LTEEGLVSFECKVVGFPTPVLSWFKDGQEL---KPGDVYQLTGT--------NSLGSYCC 156
L +G +CK G P PV+SW K+G P Q GT + G+Y C
Sbjct: 150 LAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTC 209
Query: 157 IAKNCMGQASSSAELTVED 175
+A + G+ S SA L V +
Sbjct: 210 VATSSSGETSWSAVLDVTE 228
Score = 35.1 bits (77), Expect = 4.0
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 262 DQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEG-AVNLECKVIGVP 320
D+ + C+A N G+ S L + R P+F+ + + +G V C+ G P
Sbjct: 4 DEGTYMCIAENRVGKMEASATLT-VRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNP 62
Query: 321 QPVLKWYKDGEE 332
QP + W K+G +
Sbjct: 63 QPAVFWQKEGSQ 74
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 50.8 bits (116), Expect = 8e-05
Identities = 45/180 (25%), Positives = 76/180 (42%), Gaps = 19/180 (10%)
Query: 204 VEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQ 263
+ A+++E + P P+L WY+D + G L IQ L D
Sbjct: 396 ISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGG--LRIQKLRPEDS 453
Query: 264 AEWKCVAFNDFGQSVTSCFLKL--IIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQ 321
++C A N+ G+ T +L + I P ++P + ++D L C+V G P+
Sbjct: 454 GIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRP-----VDTTVTDGMTAILRCEVSGAPK 508
Query: 322 PVLKWYKDGEELKPGDIH--RIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
P + W ++ L G + R + + G + G YTC A+N G +SA+L
Sbjct: 509 PAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATL 568
>X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor
receptor protein.
Length = 822
Score = 50.4 bits (115), Expect = 1e-04
Identities = 55/249 (22%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 147 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 263
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGKEERGV 250
+ + F KV P+P + W + D+ P V + ++ +
Sbjct: 264 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM 323
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 324 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 382
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 383 GAFLISCMV 391
Score = 46.0 bits (104), Expect = 0.002
Identities = 54/269 (20%), Positives = 108/269 (40%), Gaps = 31/269 (11%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRC 241
N+ P + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 242 HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
K + + + ++ D+ + C+ N++G S+ + ++ R +P L
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLP 262
Query: 302 AILSDEGAVNLE--CKVIGVPQPVLKWYK 328
A + N+E CKV PQP ++W K
Sbjct: 263 ANKTVALGSNVEFMCKVYSDPQPHIQWLK 291
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 148 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
>X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor
Receptor, 3-Ig Domain+2orm protein.
Length = 822
Score = 50.4 bits (115), Expect = 1e-04
Identities = 55/249 (22%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 147 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 263
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGKEERGV 250
+ + F KV P+P + W + D+ P V + ++ +
Sbjct: 264 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM 323
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 324 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 382
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 383 GAFLISCMV 391
Score = 46.0 bits (104), Expect = 0.002
Identities = 54/269 (20%), Positives = 108/269 (40%), Gaps = 31/269 (11%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRC 241
N+ P + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 242 HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
K + + + ++ D+ + C+ N++G S+ + ++ R +P L
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLP 262
Query: 302 AILSDEGAVNLE--CKVIGVPQPVLKWYK 328
A + N+E CKV PQP ++W K
Sbjct: 263 ANKTVALGSNVEFMCKVYSDPQPHIQWLK 291
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 148 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
>X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor
Receptor, 2-Ig Domain+25-1 protein.
Length = 733
Score = 50.4 bits (115), Expect = 1e-04
Identities = 55/249 (22%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 58 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 114
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 115 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 174
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGKEERGV 250
+ + F KV P+P + W + D+ P V + ++ +
Sbjct: 175 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM 234
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 235 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 293
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 294 GAFLISCMV 302
Score = 40.3 bits (90), Expect = 0.11
Identities = 36/164 (21%), Positives = 70/164 (42%), Gaps = 10/164 (6%)
Query: 174 EDIQNQLNEEEKLQLFSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSL 226
+D + +EE++ N+ P + + +E K+ P T+K P P P+L
Sbjct: 40 DDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTL 99
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W ++ + R K + + + ++ D+ + C+ N++G S+ + +
Sbjct: 100 RWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDV 158
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLE--CKVIGVPQPVLKWYK 328
+ R +P L A + N+E CKV PQP ++W K
Sbjct: 159 VERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 202
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 59 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 114
>X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA for
fibroblast growth factor receptor-FLG. ).
Length = 822
Score = 50.4 bits (115), Expect = 1e-04
Identities = 55/249 (22%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 147 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 263
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGKEERGV 250
+ + F KV P+P + W + D+ P V + ++ +
Sbjct: 264 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM 323
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 324 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 382
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 383 GAFLISCMV 391
Score = 46.0 bits (104), Expect = 0.002
Identities = 54/269 (20%), Positives = 108/269 (40%), Gaps = 31/269 (11%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRC 241
N+ P + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 242 HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
K + + + ++ D+ + C+ N++G S+ + ++ R +P L
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLP 262
Query: 302 AILSDEGAVNLE--CKVIGVPQPVLKWYK 328
A + N+E CKV PQP ++W K
Sbjct: 263 ANKTVALGSNVEFMCKVYSDPQPHIQWLK 291
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 148 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
>X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for
fibroblast growth factor (FGF) receptor. ).
Length = 822
Score = 50.4 bits (115), Expect = 1e-04
Identities = 55/249 (22%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 147 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 263
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGKEERGV 250
+ + F KV P+P + W + D+ P V + ++ +
Sbjct: 264 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM 323
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 324 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 382
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 383 GAFLISCMV 391
Score = 46.0 bits (104), Expect = 0.002
Identities = 54/269 (20%), Positives = 108/269 (40%), Gaps = 31/269 (11%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRC 241
N+ P + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 242 HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
K + + + ++ D+ + C+ N++G S+ + ++ R +P L
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLP 262
Query: 302 AILSDEGAVNLE--CKVIGVPQPVLKWYK 328
A + N+E CKV PQP ++W K
Sbjct: 263 ANKTVALGSNVEFMCKVYSDPQPHIQWLK 291
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 148 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
>M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 733
Score = 50.4 bits (115), Expect = 1e-04
Identities = 55/249 (22%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 58 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 114
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 115 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 174
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGKEERGV 250
+ + F KV P+P + W + D+ P V + ++ +
Sbjct: 175 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM 234
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 235 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 293
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 294 GAFLISCMV 302
Score = 40.3 bits (90), Expect = 0.11
Identities = 36/164 (21%), Positives = 70/164 (42%), Gaps = 10/164 (6%)
Query: 174 EDIQNQLNEEEKLQLFSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSL 226
+D + +EE++ N+ P + + +E K+ P T+K P P P+L
Sbjct: 40 DDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTL 99
Query: 227 LWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLI 286
W ++ + R K + + + ++ D+ + C+ N++G S+ + +
Sbjct: 100 RWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDV 158
Query: 287 IPRHYKKPRFLENLQAILSDEGAVNLE--CKVIGVPQPVLKWYK 328
+ R +P L A + N+E CKV PQP ++W K
Sbjct: 159 VERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 202
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 59 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 114
>BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein.
Length = 820
Score = 50.4 bits (115), Expect = 1e-04
Identities = 55/249 (22%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 147 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 263
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGKEERGV 250
+ + F KV P+P + W + D+ P V + ++ +
Sbjct: 264 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM 323
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 324 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 382
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 383 GAFLISCMV 391
Score = 46.0 bits (104), Expect = 0.002
Identities = 54/269 (20%), Positives = 108/269 (40%), Gaps = 31/269 (11%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRC 241
N+ P + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 242 HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
K + + + ++ D+ + C+ N++G S+ + ++ R +P L
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLP 262
Query: 302 AILSDEGAVNLE--CKVIGVPQPVLKWYK 328
A + N+E CKV PQP ++W K
Sbjct: 263 ANKTVALGSNVEFMCKVYSDPQPHIQWLK 291
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 148 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
>AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 822
Score = 50.4 bits (115), Expect = 1e-04
Identities = 55/249 (22%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 147 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 263
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGKEERGV 250
+ + F KV P+P + W + D+ P V + ++ +
Sbjct: 264 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM 323
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 324 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 382
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 383 GAFLISCMV 391
Score = 46.0 bits (104), Expect = 0.002
Identities = 54/269 (20%), Positives = 108/269 (40%), Gaps = 31/269 (11%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRC 241
N+ P + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 242 HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
K + + + ++ D+ + C+ N++G S+ + ++ R +P L
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLP 262
Query: 302 AILSDEGAVNLE--CKVIGVPQPVLKWYK 328
A + N+E CKV PQP ++W K
Sbjct: 263 ANKTVALGSNVEFMCKVYSDPQPHIQWLK 291
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 148 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 50.4 bits (115), Expect = 1e-04
Identities = 70/276 (25%), Positives = 105/276 (38%), Gaps = 56/276 (20%)
Query: 114 VSFECKVVGFPTPVLSWFKDGQELKP-GDVYQLTGTNSL----------GSYCCIAKNCM 162
V C G P P +SW K G +L G Y+++ + +L G Y C A+N
Sbjct: 5 VVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSA 64
Query: 163 GQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSV-EAKIDEPFRFTIKVAIP 221
G A LTV QA V L SV A +E + +
Sbjct: 65 GVAHKHVFLTV-------------------QASPVVKPLPSVVRAVAEEEVLLPCEASGI 105
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P++ W ++ V + + L I D + C+A N G ++
Sbjct: 106 PRPTITWQKEGLNVATGVSTQVLPGGQ----LRIAHASPEDAGNYLCIAKNSAGSAMGKT 161
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGA-VNLECKVIGVPQPVLKWYKDGEELKPGD--- 337
L + +P P L + + EG+ L CK G P+P + W KDG+ + +
Sbjct: 162 RLVVQVP-----PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKF 216
Query: 338 --------IHRIISGQDGTCSLGTYTCEASNCMGVA 365
+ + + GQD GTYTC A N +G A
Sbjct: 217 TIQPSGELLVKNLEGQDA----GTYTCTAENAVGRA 248
Score = 39.9 bits (89), Expect = 0.14
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 15/90 (16%)
Query: 98 PRFMEN-LQAVLTEEGLVSF-ECKVVGFPTPVLSWFKDGQELKPGD------------VY 143
P +EN L + T EG +F CK G P P ++W KDGQ + + V
Sbjct: 168 PPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVK 227
Query: 144 QLTGTNSLGSYCCIAKNCMGQASSSAELTV 173
L G ++ G+Y C A+N +G+A LT+
Sbjct: 228 NLEGQDA-GTYTCTAENAVGRARRRVHLTI 256
Score = 34.7 bits (76), Expect = 5.3
Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 6/72 (8%)
Query: 307 EGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRIISG------QDGTCSLGTYTCEASN 360
E V L C+ G+P+P + W K+G + G +++ G G Y C A N
Sbjct: 93 EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKN 152
Query: 361 CMGVAASSASLL 372
G A L+
Sbjct: 153 SAGSAMGKTRLV 164
>AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth factor
receptor 1 isoform 1 precursor variant protein.
Length = 814
Score = 50.4 bits (115), Expect = 1e-04
Identities = 55/249 (22%), Positives = 100/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 141 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 197
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 198 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 257
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGKEERGV 250
+ + F KV P+P + W + D+ P V + ++ +
Sbjct: 258 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEM 317
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 318 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 376
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 377 GAFLISCMV 385
Score = 43.6 bits (98), Expect = 0.011
Identities = 47/229 (20%), Positives = 92/229 (40%), Gaps = 29/229 (12%)
Query: 128 LSWFKDGQELKPGDVYQLTGTN---------SLGSYCCIAKNCMGQASSSAELTVEDI-- 176
++W +DG +L + ++TG G Y C+ + G ++ + V D
Sbjct: 58 INWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALP 117
Query: 177 --------QNQLNEEEKLQLFSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP---- 221
+ +EE++ N+ P + + +E K+ P T+K P
Sbjct: 118 SSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGT 177
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSC 281
P P+L W ++ + R K + + + ++ D+ + C+ N++G S+
Sbjct: 178 PNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHT 236
Query: 282 FLKLIIPRHYKKPRFLENLQAILSDEGAVNLE--CKVIGVPQPVLKWYK 328
+ ++ R +P L A + N+E CKV PQP ++W K
Sbjct: 237 YQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 285
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 142 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 197
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 50.4 bits (115), Expect = 1e-04
Identities = 116/600 (19%), Positives = 245/600 (40%), Gaps = 46/600 (7%)
Query: 2415 DLQKVDVTIEMPEIAQLDKCQPFYANLHELMQSVDLAKQLQKSI--TISESVIEPNIETE 2472
+L + ++T+EM + +D+ L ++ ++ +L++ QKS+ ++E ++ E
Sbjct: 407 ELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLE 466
Query: 2473 PNPQSPVYLASQLKMALLVLYNQDIESLEVMAPHLTK--DKLKVISEIVHNLCDDLTQVM 2530
QS +L+ ++S+E A + K + + +S+ V L +++ Q
Sbjct: 467 MENQSLTKTVEELRTT--------VDSVEGNASKILKMEKENQRLSKKVEILENEIVQEK 518
Query: 2531 EAVQSNQNTSESSVKESVQKANVVEQ-DLNSPEEIDEIFETKTPLQEVGTAQNIVXXXXX 2589
+++Q+ QN S+ +KE Q +E NS +I + + L + ++
Sbjct: 519 QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA 578
Query: 2590 XXXXXXXXKHETIDTAEIKSVVGKITDNLFSIEAAQSIEVKEDFSDVKSTDLRVTDSVTE 2649
K I IK K++ F + ++K++ K R + E
Sbjct: 579 EARVKDIEKENKILHESIKETSSKLSKIEF-----EKRQIKKELEHYKEKGERAEELENE 633
Query: 2650 V--LESSDVRVIENVSKSDDVPTNINLL-VDDSLLEID--KAVKSTEALKNIP-QRDLAE 2703
+ LE + + + ++ I L ++S LE + K K+ ++ KN+ Q + E
Sbjct: 634 LHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLE 693
Query: 2704 NE-QQLGEDTTGSKQKVVELPDTIDDVSQDMIVEHLPTSEVKLLEGQLLAAEENTLSEAL 2762
E QL E+ ++ V +++ S M L E++ + QL E L
Sbjct: 694 KENSQLDEENLELRRNV----ESLKCASMKMAQLQLENKELESEKEQLKKG-----LELL 744
Query: 2763 KSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKSKLVEELQT------IADSKSQKMIEES 2816
K+S ++ E ++ ++ E +K +++L++ + + QK +EE
Sbjct: 745 KASFKKTER-LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Query: 2817 TTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESITELNQKSSDFTKSQSIVSDVS 2876
L K+ E + + EK+ K + K + ++ + ++
Sbjct: 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE 863
Query: 2877 QEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHETIQTLNSNLENEMCESLKIEQ 2936
+E +S EI KE + ++L E + I+TL + E+ + E LK +Q
Sbjct: 864 KE---NKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ 920
Query: 2937 AVSAETTESTVESQRVASEVILELVSEQLKKDQAESSNSQTAENIVREIVVTSE-ITALE 2995
++ + + T E +++ L EQ D+ + S+ + + + + E I ALE
Sbjct: 921 -MNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALE 979
>AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein.
Length = 1237
Score = 50.4 bits (115), Expect = 1e-04
Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 27/221 (12%)
Query: 152 GSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPK-FVHGLKSVEAKI-- 208
G Y C A+N G A + A L Q+++ + ++AP V LK
Sbjct: 41 GVYVCHARNAHGHAQAGALL-------QVHQPPESPPADPDEAPAPVVEPLKCAPKTFWV 93
Query: 209 --DEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEW 266
+ +F V PEP + W+ + +P+ R + ++ G F L + + D+ +
Sbjct: 94 NEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLY 153
Query: 267 KCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDE-GAVNLECKVIGVPQPVLK 325
C A N GQ++++ L + PR RF LQ + E G LECKV P
Sbjct: 154 VCAARNSAGQTLSAVQLHVKEPR----LRFTRPLQDVEGREHGIAVLECKVPNSRIPT-A 208
Query: 326 WYKDGEELKP---------GDIHRIISGQDGTCSLGTYTCE 357
W+++ + L P G + R+I + G Y CE
Sbjct: 209 WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE 249
Score = 38.3 bits (85), Expect = 0.43
Identities = 62/220 (28%), Positives = 91/220 (41%), Gaps = 18/220 (8%)
Query: 116 FECKVVGFPTPVLSWFKDGQELKPGDVYQLTGTNSLGSYCCIAKNCMGQASSSAELTVED 175
F C V+G P P + W +G+ L P D +L + G + C QA L V
Sbjct: 101 FRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMYRDRDGGFVLKVLYC--QAKDRG-LYVCA 156
Query: 176 IQNQLNEE-EKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQP 234
+N + +QL K +F L+ VE + KV P+ W+R+DQ
Sbjct: 157 ARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPT-AWFREDQR 215
Query: 235 VDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLK-LIIPRHYKK 293
+ R + EE V L I L+ D + C ++V + +K I+ R +K
Sbjct: 216 L-LPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC-EMRGRVRTVANVTVKGPILKRLPRK 273
Query: 294 PRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
LE A+L E LE V G +W +DGEEL
Sbjct: 274 LDVLEGENAVLLVE---TLEAGVEG------RWSRDGEEL 304
Score = 38.3 bits (85), Expect = 0.43
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 228 WYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLII 287
WY+D Q V+ES + + R L + + D E++C + V++ F +
Sbjct: 585 WYKDGQKVEESELLVVKMDGRK-HRLILPEAKVQDSGEFECRT-----EGVSAFFGVTVQ 638
Query: 288 --PRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD 337
P H PR + AI S+ V L C+V PV +WYKDG+E++ D
Sbjct: 639 DPPVHIVDPREHVFVHAITSE--CVMLACEVDREDAPV-RWYKDGQEVEESD 687
Score = 34.3 bits (75), Expect = 7.0
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 13/119 (10%)
Query: 222 PEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFND---FGQSV 278
P + W +D + V ES L KE+ V L + A++ D E+ C ++ F +V
Sbjct: 761 PWAEVRWTKDGEEVVESPALLLQKEDT-VRRLVLPAVQLEDSGEYLCEIDDESASFTVTV 819
Query: 279 TSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGD 337
T +++I PR + + I V L C++ PV +WYKDG E++ +
Sbjct: 820 TEPPVRIIYPR--------DEVTLIAVTLECVVLMCELSREDAPV-RWYKDGLEVEESE 869
>Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 238 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 296
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 297 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 338
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 339 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 396
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 397 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 453
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 454 PVPSVQWLDEDG 465
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 50.0 bits (114), Expect = 1e-04
Identities = 194/1068 (18%), Positives = 428/1068 (40%), Gaps = 86/1068 (8%)
Query: 1958 EPLQNLHTQLIHVQEVVLSGVQEDSISLDIDSAESIVQT-ISDVHKKISAKLELETVNVS 2016
E LQ L Q E + +++ +L + E I Q I ++++K KL+++ +
Sbjct: 629 EKLQVLKQQYQTEMEKLREKCEQEKETL-LKDKEIIFQAHIEEMNEKTLEKLDVKQTELE 687
Query: 2017 DKDVALIFEVDKDLHAIQDSIKALKNQP--AAQDIK-DVTKQIQDVEKSLHVLVASENVI 2073
L EV K H +++ + LK+Q Q+++ + +Q ++ + ++ V
Sbjct: 688 SLSSELS-EVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 746
Query: 2074 TDVKDKIPKGSTEQLVQHINQYXXXXXXXXXXXXXXXXXDLKET---IEMAKDLRETFVT 2130
+K K QL + + D+K + ++ A + F +
Sbjct: 747 IQRTEKALKDQINQLELLLKE-RDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQS 805
Query: 2131 SDMINDEVAESIKEEIL-IEQARLAHKLQKAISALQV-QVFDSAQEMVPELST------E 2182
E ++ +E++ ++Q L + ++ + QV +V +++ EL +
Sbjct: 806 YQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQD 865
Query: 2183 IFQRVARVTAQLQADLMAVTGVHITIQAPPYVLDEVAKSLETISTENRLVPESAQGDKLV 2242
+ Q++ + ++++ + ++T V+ + E K + + EN ++ K +
Sbjct: 866 LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI-LVEKENMILQMREGQKKEI 924
Query: 2243 SIV--------ENVNMFENTADPPIQPKPKELSNITVEPEEVNITQLLEDVSSNERVINE 2294
I+ +++++ + + + K++ + + +E+ T L + + E + +
Sbjct: 925 EILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQET-LKKKLLDQEAKLKK 983
Query: 2295 NLVTVTQEVAVAQMETNMDIAGVTKKTQDGLIKDDIKSFSIS--EEAQSIFEQGSPEVYN 2352
L E++ + + N + + + G I D + + E+ +S+ E E+ +
Sbjct: 984 ELENTALELSQKEKQFNAKMLEMAQANSAG-ISDAVSRLETNQKEQIESLTEVHRRELND 1042
Query: 2353 VLNAEELASNQTFSA--DSASNNMPDNELDIVEPVLVCSVPASSLDDLEGSVN--PKTGL 2408
V++ E NQ + + + E ++ E + +++ + + G+
Sbjct: 1043 VISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGV 1102
Query: 2409 VTDEKIDLQKVDVTIEMPEIAQLDKCQP-FYANLHELMQSVDLAKQLQKSITISESVIEP 2467
D ++ + + + + L + + A+L +L VDL K L+++ + E ++E
Sbjct: 1103 KQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKL--EVDLNKSLKENTFLQEQLVEL 1160
Query: 2468 NIETEPNPQSPVYLASQLK------MALLVLYNQDIESLEVMAPHLTKDKLKVISEIVHN 2521
+ E + + L S+LK +L + + +SLE + L KL I +
Sbjct: 1161 KMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKS--LEFKKLSEELAIQLD 1218
Query: 2522 LCDDLTQVMEAVQSNQ--NTSESSVKESVQKANVVEQDLNSPEEI-----DEIFETKTPL 2574
+C T+ + ++N+ N S S + + + + +E + E + L
Sbjct: 1219 ICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQL 1278
Query: 2575 QEVGTAQNIVXXXXXXXXXXXXXKHETIDT--AEIKSVVG-KITDNLFSIEAAQSIEVKE 2631
+++ QN + K I + A+I+S+V K Q+ KE
Sbjct: 1279 RQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKE 1338
Query: 2632 D-FSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPT-NINLLVDDSLLEIDKAVKS 2689
+ +K ++VT + E + +E S S + N+ L SL E + A+ S
Sbjct: 1339 SCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISS 1398
Query: 2690 TEALKNIPQRDLAENEQQLG-EDTTGSKQKVVELPDTIDDVSQDMIVEHLPTSEVKLLEG 2748
+ + +L + Q L + T SK+K+ L + +DD S SE K
Sbjct: 1399 LRKQYDEEKCELLDQVQDLSFKVDTLSKEKISAL-EQVDDWSNKF-------SEWKKKAQ 1450
Query: 2749 QLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPE------IKSKLVEELQ 2802
+NT+ E L+ L K+ E D ++L+K + + +K ++ ++
Sbjct: 1451 SRFTQHQNTVKE-LQIQLEL--KSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKS 1507
Query: 2803 TIADSKSQKMIE-ESTTRETVESPLITTGKTTETP--NDITSMNVGETEKQRKESITELN 2859
+ +S E +S T +E T KT E N++ + + + KE + +L
Sbjct: 1508 KMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQ 1567
Query: 2860 QKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHETIQT 2919
+ + V + ++IL + +++ K + K+ VNL + + E ++
Sbjct: 1568 HFQELGEEKDNRVKEAEEKILT---LENQVYSMKAELETKKKELEHVNLSVKSKEEELKA 1624
Query: 2920 LNSNLENEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKK 2967
L LE+E L E AE + ++ Q ++ +E EQ KK
Sbjct: 1625 LEDRLESESAAKL-AELKRKAEQKIAAIKKQLLSQ---MEEKEEQYKK 1668
Score = 39.1 bits (87), Expect = 0.25
Identities = 135/671 (20%), Positives = 274/671 (40%), Gaps = 71/671 (10%)
Query: 2318 TKKTQDGLIKDDIKSFSISE-EAQSIFEQGSPEVYNVLNAEELASNQTFSADSASNNMPD 2376
T K ++ L+ IK+ ++SE EAQ + E N LN T + N +
Sbjct: 1257 TTKVKEALL---IKTCTVSELEAQL---RQLTEEQNTLNIS--FQQATHQLEEKENQIKS 1308
Query: 2377 NELDIVEPVLVCSVPASSLDDLEGSVNPKTGLVTDEKIDL-QKVDVTIEMPEIAQLDKCQ 2435
+ DI V + + + + K +T K +L + ++ M E + K +
Sbjct: 1309 MKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVE 1368
Query: 2436 PFYANLHELMQSVDLAKQLQKSITISESVIEPNIETEPNPQSPVYLASQLKMALLVLYNQ 2495
++L + Q DL QLQ SI++SE E I + L Q L +Q
Sbjct: 1369 --ISSLSK--QLTDLNVQLQNSISLSEK--EAAISS---------LRKQYDEEKCELLDQ 1413
Query: 2496 DIESLEVMAPHLTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVE 2555
++ L L+K+K+ + E V + + ++ + QS +++VKE + +
Sbjct: 1414 -VQDLSFKVDTLSKEKISAL-EQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKS 1471
Query: 2556 QDLNSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKIT 2615
++ + E+ ++I K L + + + K ++T E+KS +I
Sbjct: 1472 KE--AYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET-ELKSQTARIM 1528
Query: 2616 DNLFSIEAAQSIEVKEDFSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPTNINLL 2675
+ L ++IE+ E ++V L+ + ++ V+ +++ + + N
Sbjct: 1529 E-LEDHITQKTIEI-ESLNEV----LKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKE 1582
Query: 2676 VDDSLLEIDKAVKSTEALKNIPQRDLAENEQQLGEDTTGSKQKVVELPDTIDDVSQDMIV 2735
++ +L ++ V S +A +L +++L K K EL D + +
Sbjct: 1583 AEEKILTLENQVYSMKA-------ELETKKKELEHVNLSVKSKEEELKALEDRLESESAA 1635
Query: 2736 EHLPTSEVKLLEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKS 2795
+ +E+K Q +AA + L ++ +K TE+ L + + L + E I
Sbjct: 1636 K---LAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHI-- 1690
Query: 2796 KLVEELQTIADSKSQKMIEESTTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESI 2855
L E+L+++ S+S+ +I + + T + D + G +K +E I
Sbjct: 1691 -LEEKLKSVESSQSETLIVPRSAKN-------VAAYTEQEEAD----SQGCVQKTYEEKI 1738
Query: 2856 TELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHE 2915
+ L + ++ K V +E + H E++ +++L K + AE HE
Sbjct: 1739 SVLQRNLTEKEKLLQRVGQEKEETVSSHF---EMRCQYQERLIKLE-HAEAK-----QHE 1789
Query: 2916 TIQTLNSNLENEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKKD-QAESSN 2974
Q++ +L+ E+ E K + A+ E + ++ LE V + ++K Q +
Sbjct: 1790 D-QSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT 1848
Query: 2975 SQTAENIVREI 2985
Q E ++E+
Sbjct: 1849 CQILEQKIKEL 1859
Score = 38.3 bits (85), Expect = 0.43
Identities = 87/462 (18%), Positives = 189/462 (40%), Gaps = 36/462 (7%)
Query: 733 LMASAATASKSLEIIS-SLINPLSEILSITDTIQ-ESASETIEVQRTLFSRLPKPLKVLQ 790
+ A T K LE ++ S+ + E+ ++ D ++ ESA++ E++R K Q
Sbjct: 1597 MKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKR----------KAEQ 1646
Query: 791 QTLTIIEKCIDVESDNRTLVKKTCVSIMEKCGNAIQNLVSEINAIEKKEYLLLSENVCNE 850
+ I ++ + + KK S + + +Q E++ +E+K L E+ +E
Sbjct: 1647 KIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEK--LKSVESSQSE 1704
Query: 851 LDVVSNEISTVVNFST-ESIKTNNLLNETTEVKLESTVESKHLTDTQKALFELKGPLRSL 909
+V V ++ E + + +T E K+ +V ++LT+ +K L +
Sbjct: 1705 TLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKI--SVLQRNLTEKEKLLQRVGQEKEET 1762
Query: 910 LYIVDSAESGKIVDISQVNNSEVILNDMSASIQDLQSALEQIESLSVLECATSLNKYNTE 969
+ + ++ ++E ++ + I LQ LE+ L A + K E
Sbjct: 1763 VSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK---E 1819
Query: 970 IIENVMEPVLQLRSSFEKMSTEIKAEDKIQLNKVLSSIKE--NLTVISSYINKVENN--I 1025
+N ++ L + F+ + ++ E ++ + IKE + V +++VE
Sbjct: 1820 GGKNNIQAKQNLENVFDDVQKTLQ-EKELTCQILEQKIKELDSCLVRQKEVHRVEMEELT 1878
Query: 1026 GAFDVLQNENKLEALQKMAETLI-SLEKNLPTLDTMPQVQGNMNSFHKNLTKALEKVIES 1084
++ LQ +++ K E L + E+ + P++ NM + H +L L E
Sbjct: 1879 SKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA-ER 1937
Query: 1085 NNANKYLSMIEICDGIRRINS--------CIRDMDTDNILSLASLSNTLKIIQNQFIKNI 1136
++ + +R + ++ D + + L++ N +K +
Sbjct: 1938 EKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 1997
Query: 1137 FDSELNCCVVTNITDILIGIQETINQAQEFTTEIQYDNFQDT 1178
E N + ++ + I+ETIN+AQE E+ + ++T
Sbjct: 1998 M-REFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEET 2038
Score = 37.5 bits (83), Expect = 0.75
Identities = 52/266 (19%), Positives = 112/266 (42%), Gaps = 16/266 (6%)
Query: 839 EYLLLSENVCNELDVVSNEISTVVNFSTESI------KTNNLLNETTEVKLESTVESKHL 892
E+ LSE + +LD+ + ++ T + KTN +L+ + + +T + L
Sbjct: 1205 EFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1264
Query: 893 TDTQKALFELKGPLRSLLYIVDSAESGKIVDISQVNNSEVILNDMSASIQDLQSALE--Q 950
+ EL+ LR L ++ Q+ E + M A I+ L + E Q
Sbjct: 1265 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQ 1324
Query: 951 IESLSVLECATSLNKYNTEIIENVMEPVLQLRSSFEKMSTEIKAEDKIQLNKVLSSIKE- 1009
E + + A+ T++ + + E + ++ M E+K E K++++ + + +
Sbjct: 1325 KEGGNQQQAASEKESCITQLKKELSENI----NAVTLMKEELK-EKKVEISSLSKQLTDL 1379
Query: 1010 NLTVISSY-INKVENNIGAFDVLQNENKLEALQKMAETLISLEK-NLPTLDTMPQVQGNM 1067
N+ + +S +++ E I + +E K E L ++ + ++ + + + QV
Sbjct: 1380 NVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWS 1439
Query: 1068 NSFHKNLTKALEKVIESNNANKYLSM 1093
N F + KA + + N K L +
Sbjct: 1440 NKFSEWKKKAQSRFTQHQNTVKELQI 1465
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 50.0 bits (114), Expect = 1e-04
Identities = 70/293 (23%), Positives = 114/293 (38%), Gaps = 49/293 (16%)
Query: 97 KPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG-----DVYQLTGTN-- 149
K RF A++ ++ V+ EC G P P + W K L P Q+ +
Sbjct: 242 KARFPAETYALVGQQ--VTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSFE 299
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
G+Y C A+N G+ + + V+ P+++ + EA I
Sbjct: 300 DEGTYECEAENSKGRDTVQGRIIVQ------------------AQPEWLKVISDTEADIG 341
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCV 269
R+ A P P++ W R+ +P+ +R + + L L D ++CV
Sbjct: 342 SNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD-----LRFSKLSLEDSGMYQCV 396
Query: 270 AFNDFGQSVTSCFLKLIIPRHYKKPRF-LENLQAIL--SDEGAVNLECKVIGVPQPVLKW 326
A N G S L + P F L ++ ++ + G + + C+ P+ V+ W
Sbjct: 397 AENKHGTIYASAELAV----QALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLW 452
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
K E L + R+ DGT + G YTC A N MG A S+ L
Sbjct: 453 SKGTEILV--NSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGIL 503
Score = 38.3 bits (85), Expect = 0.43
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Query: 305 SDEGAVNLECKVIGVPQPVLKWYKDGEELK--PGDIHRIISGQ------DGTCSLGTYTC 356
S E V L C+ P +W +G E+K PG H+++ G G Y C
Sbjct: 52 STEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQC 111
Query: 357 EASNCMGVAASSASLLGF 374
ASN +G S ++L F
Sbjct: 112 LASNPVGTVVSREAILRF 129
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 50.0 bits (114), Expect = 1e-04
Identities = 70/293 (23%), Positives = 114/293 (38%), Gaps = 49/293 (16%)
Query: 97 KPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG-----DVYQLTGTN-- 149
K RF A++ ++ V+ EC G P P + W K L P Q+ +
Sbjct: 242 KARFPAETYALVGQQ--VTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSFE 299
Query: 150 SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKID 209
G+Y C A+N G+ + + V+ P+++ + EA I
Sbjct: 300 DEGTYECEAENSKGRDTVQGRIIVQ------------------AQPEWLKVISDTEADIG 341
Query: 210 EPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCV 269
R+ A P P++ W R+ +P+ +R + + L L D ++CV
Sbjct: 342 SNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD-----LRFSKLSLEDSGMYQCV 396
Query: 270 AFNDFGQSVTSCFLKLIIPRHYKKPRF-LENLQAIL--SDEGAVNLECKVIGVPQPVLKW 326
A N G S L + P F L ++ ++ + G + + C+ P+ V+ W
Sbjct: 397 AENKHGTIYASAELAV----QALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLW 452
Query: 327 YKDGEELKPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASSASL 371
K E L + R+ DGT + G YTC A N MG A S+ L
Sbjct: 453 SKGTEILV--NSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGIL 503
Score = 38.3 bits (85), Expect = 0.43
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Query: 305 SDEGAVNLECKVIGVPQPVLKWYKDGEELK--PGDIHRIISGQ------DGTCSLGTYTC 356
S E V L C+ P +W +G E+K PG H+++ G G Y C
Sbjct: 52 STEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQC 111
Query: 357 EASNCMGVAASSASLLGF 374
ASN +G S ++L F
Sbjct: 112 LASNPVGTVVSREAILRF 129
>X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor
Receptor, 2 Ig-Domain Form protein.
Length = 731
Score = 50.0 bits (114), Expect = 1e-04
Identities = 56/254 (22%), Positives = 102/254 (40%), Gaps = 22/254 (8%)
Query: 82 KMIHNSHPT-VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG 140
K N+ P V + P ME + V F+C G P P L W K+G+E KP
Sbjct: 50 KETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD 109
Query: 141 DVYQLTGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFV 198
+++ G ++ I + + + VE+ +N +L + ++ P
Sbjct: 110 --HRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQ 167
Query: 199 HGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGK 245
GL + + + F KV P+P + W + D+ P V +
Sbjct: 168 AGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNT 227
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQA 302
++ + L ++ + F D E+ C+A N G S S +L ++ ++P + + L+
Sbjct: 228 TDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEI 286
Query: 303 ILSDEGAVNLECKV 316
I+ GA + C V
Sbjct: 287 IIYCTGAFLISCMV 300
Score = 41.9 bits (94), Expect = 0.035
Identities = 35/162 (21%), Positives = 68/162 (41%), Gaps = 8/162 (4%)
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLW 228
+D + +EE++ N + + +E K+ P T+K P P P+L W
Sbjct: 40 DDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRW 99
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
++ + R K + + + ++ D+ + C+ N++G S+ + ++
Sbjct: 100 LKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVE 158
Query: 289 RHYKKPRFLENLQAILSDEGAVNLE--CKVIGVPQPVLKWYK 328
R +P L A + N+E CKV PQP ++W K
Sbjct: 159 RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
Score = 36.3 bits (80), Expect = 1.7
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 63 YWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 112
>X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor
Receptor, 3 Ig-Domain Form protein.
Length = 820
Score = 50.0 bits (114), Expect = 1e-04
Identities = 56/254 (22%), Positives = 102/254 (40%), Gaps = 22/254 (8%)
Query: 82 KMIHNSHPT-VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG 140
K N+ P V + P ME + V F+C G P P L W K+G+E KP
Sbjct: 139 KETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD 198
Query: 141 DVYQLTGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFV 198
+++ G ++ I + + + VE+ +N +L + ++ P
Sbjct: 199 --HRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQ 256
Query: 199 HGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGK 245
GL + + + F KV P+P + W + D+ P V +
Sbjct: 257 AGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNT 316
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQA 302
++ + L ++ + F D E+ C+A N G S S +L ++ ++P + + L+
Sbjct: 317 TDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEI 375
Query: 303 ILSDEGAVNLECKV 316
I+ GA + C V
Sbjct: 376 IIYCTGAFLISCMV 389
Score = 47.6 bits (108), Expect = 7e-04
Identities = 53/267 (19%), Positives = 106/267 (39%), Gaps = 29/267 (10%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAPKFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRCHL 243
N + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGG 203
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI 303
K + + + ++ D+ + C+ N++G S+ + ++ R +P L A
Sbjct: 204 YKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLPAN 262
Query: 304 LSDEGAVNLE--CKVIGVPQPVLKWYK 328
+ N+E CKV PQP ++W K
Sbjct: 263 KTVALGSNVEFMCKVYSDPQPHIQWLK 289
Score = 36.3 bits (80), Expect = 1.7
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 152 YWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 201
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 50.0 bits (114), Expect = 1e-04
Identities = 194/1068 (18%), Positives = 428/1068 (40%), Gaps = 86/1068 (8%)
Query: 1958 EPLQNLHTQLIHVQEVVLSGVQEDSISLDIDSAESIVQT-ISDVHKKISAKLELETVNVS 2016
E LQ L Q E + +++ +L + E I Q I ++++K KL+++ +
Sbjct: 629 EKLQVLKQQYQTEMEKLREKCEQEKETL-LKDKEIIFQAHIEEMNEKTLEKLDVKQTELE 687
Query: 2017 DKDVALIFEVDKDLHAIQDSIKALKNQP--AAQDIK-DVTKQIQDVEKSLHVLVASENVI 2073
L EV K H +++ + LK+Q Q+++ + +Q ++ + ++ V
Sbjct: 688 SLSSELS-EVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 746
Query: 2074 TDVKDKIPKGSTEQLVQHINQYXXXXXXXXXXXXXXXXXDLKET---IEMAKDLRETFVT 2130
+K K QL + + D+K + ++ A + F +
Sbjct: 747 IQRTEKALKDQINQLELLLKE-RDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQS 805
Query: 2131 SDMINDEVAESIKEEIL-IEQARLAHKLQKAISALQV-QVFDSAQEMVPELST------E 2182
E ++ +E++ ++Q L + ++ + QV +V +++ EL +
Sbjct: 806 YQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQD 865
Query: 2183 IFQRVARVTAQLQADLMAVTGVHITIQAPPYVLDEVAKSLETISTENRLVPESAQGDKLV 2242
+ Q++ + ++++ + ++T V+ + E K + + EN ++ K +
Sbjct: 866 LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI-LVEKENMILQMREGQKKEI 924
Query: 2243 SIV--------ENVNMFENTADPPIQPKPKELSNITVEPEEVNITQLLEDVSSNERVINE 2294
I+ +++++ + + + K++ + + +E+ T L + + E + +
Sbjct: 925 EILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQET-LKKKLLDQEAKLKK 983
Query: 2295 NLVTVTQEVAVAQMETNMDIAGVTKKTQDGLIKDDIKSFSIS--EEAQSIFEQGSPEVYN 2352
L E++ + + N + + + G I D + + E+ +S+ E E+ +
Sbjct: 984 ELENTALELSQKEKQFNAKMLEMAQANSAG-ISDAVSRLETNQKEQIESLTEVHRRELND 1042
Query: 2353 VLNAEELASNQTFSA--DSASNNMPDNELDIVEPVLVCSVPASSLDDLEGSVN--PKTGL 2408
V++ E NQ + + + E ++ E + +++ + + G+
Sbjct: 1043 VISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGV 1102
Query: 2409 VTDEKIDLQKVDVTIEMPEIAQLDKCQP-FYANLHELMQSVDLAKQLQKSITISESVIEP 2467
D ++ + + + + L + + A+L +L VDL K L+++ + E ++E
Sbjct: 1103 KQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKL--EVDLNKSLKENTFLQEQLVEL 1160
Query: 2468 NIETEPNPQSPVYLASQLK------MALLVLYNQDIESLEVMAPHLTKDKLKVISEIVHN 2521
+ E + + L S+LK +L + + +SLE + L KL I +
Sbjct: 1161 KMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKS--LEFKKLSEELAIQLD 1218
Query: 2522 LCDDLTQVMEAVQSNQ--NTSESSVKESVQKANVVEQDLNSPEEI-----DEIFETKTPL 2574
+C T+ + ++N+ N S S + + + + +E + E + L
Sbjct: 1219 ICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQL 1278
Query: 2575 QEVGTAQNIVXXXXXXXXXXXXXKHETIDT--AEIKSVVG-KITDNLFSIEAAQSIEVKE 2631
+++ QN + K I + A+I+S+V K Q+ KE
Sbjct: 1279 RQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKE 1338
Query: 2632 D-FSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPT-NINLLVDDSLLEIDKAVKS 2689
+ +K ++VT + E + +E S S + N+ L SL E + A+ S
Sbjct: 1339 SCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISS 1398
Query: 2690 TEALKNIPQRDLAENEQQLG-EDTTGSKQKVVELPDTIDDVSQDMIVEHLPTSEVKLLEG 2748
+ + +L + Q L + T SK+K+ L + +DD S SE K
Sbjct: 1399 LRKQYDEEKCELLDQVQDLSFKVDTLSKEKISAL-EQVDDWSNKF-------SEWKKKAQ 1450
Query: 2749 QLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPE------IKSKLVEELQ 2802
+NT+ E L+ L K+ E D ++L+K + + +K ++ ++
Sbjct: 1451 SRFTQHQNTVKE-LQIQLEL--KSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKS 1507
Query: 2803 TIADSKSQKMIE-ESTTRETVESPLITTGKTTETP--NDITSMNVGETEKQRKESITELN 2859
+ +S E +S T +E T KT E N++ + + + KE + +L
Sbjct: 1508 KMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQ 1567
Query: 2860 QKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHETIQT 2919
+ + V + ++IL + +++ K + K+ VNL + + E ++
Sbjct: 1568 HFQELGEEKDNRVKEAEEKILT---LENQVYSMKAELETKKKELEHVNLSVKSKEEELKA 1624
Query: 2920 LNSNLENEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKK 2967
L LE+E L E AE + ++ Q ++ +E EQ KK
Sbjct: 1625 LEDRLESESAAKL-AELKRKAEQKIAAIKKQLLSQ---MEEKEEQYKK 1668
Score = 39.1 bits (87), Expect = 0.25
Identities = 135/671 (20%), Positives = 274/671 (40%), Gaps = 71/671 (10%)
Query: 2318 TKKTQDGLIKDDIKSFSISE-EAQSIFEQGSPEVYNVLNAEELASNQTFSADSASNNMPD 2376
T K ++ L+ IK+ ++SE EAQ + E N LN T + N +
Sbjct: 1257 TTKVKEALL---IKTCTVSELEAQL---RQLTEEQNTLNIS--FQQATHQLEEKENQIKS 1308
Query: 2377 NELDIVEPVLVCSVPASSLDDLEGSVNPKTGLVTDEKIDL-QKVDVTIEMPEIAQLDKCQ 2435
+ DI V + + + + K +T K +L + ++ M E + K +
Sbjct: 1309 MKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVE 1368
Query: 2436 PFYANLHELMQSVDLAKQLQKSITISESVIEPNIETEPNPQSPVYLASQLKMALLVLYNQ 2495
++L + Q DL QLQ SI++SE E I + L Q L +Q
Sbjct: 1369 --ISSLSK--QLTDLNVQLQNSISLSEK--EAAISS---------LRKQYDEEKCELLDQ 1413
Query: 2496 DIESLEVMAPHLTKDKLKVISEIVHNLCDDLTQVMEAVQSNQNTSESSVKESVQKANVVE 2555
++ L L+K+K+ + E V + + ++ + QS +++VKE + +
Sbjct: 1414 -VQDLSFKVDTLSKEKISAL-EQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKS 1471
Query: 2556 QDLNSPEEIDEIFETKTPLQEVGTAQNIVXXXXXXXXXXXXXKHETIDTAEIKSVVGKIT 2615
++ + E+ ++I K L + + + K ++T E+KS +I
Sbjct: 1472 KE--AYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET-ELKSQTARIM 1528
Query: 2616 DNLFSIEAAQSIEVKEDFSDVKSTDLRVTDSVTEVLESSDVRVIENVSKSDDVPTNINLL 2675
+ L ++IE+ E ++V L+ + ++ V+ +++ + + N
Sbjct: 1529 E-LEDHITQKTIEI-ESLNEV----LKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKE 1582
Query: 2676 VDDSLLEIDKAVKSTEALKNIPQRDLAENEQQLGEDTTGSKQKVVELPDTIDDVSQDMIV 2735
++ +L ++ V S +A +L +++L K K EL D + +
Sbjct: 1583 AEEKILTLENQVYSMKA-------ELETKKKELEHVNLSVKSKEEELKALEDRLESESAA 1635
Query: 2736 EHLPTSEVKLLEGQLLAAEENTLSEALKSSLVTVQKTTETPLDDTSVDLVKIAGEPEIKS 2795
+ +E+K Q +AA + L ++ +K TE+ L + + L + E I
Sbjct: 1636 K---LAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHI-- 1690
Query: 2796 KLVEELQTIADSKSQKMIEESTTRETVESPLITTGKTTETPNDITSMNVGETEKQRKESI 2855
L E+L+++ S+S+ +I + + T + D + G +K +E I
Sbjct: 1691 -LEEKLKSVESSQSETLIVPRSAKN-------VAAYTEQEEAD----SQGCVQKTYEEKI 1738
Query: 2856 TELNQKSSDFTKSQSIVSDVSQEILVEHLISDEIKFTKEQQLAKEDLTAEVNLPLVTGHE 2915
+ L + ++ K V +E + H E++ +++L K + AE HE
Sbjct: 1739 SVLQRNLTEKEKLLQRVGQEKEETVSSHF---EMRCQYQERLIKLE-HAEAK-----QHE 1789
Query: 2916 TIQTLNSNLENEMCESLKIEQAVSAETTESTVESQRVASEVILELVSEQLKKD-QAESSN 2974
Q++ +L+ E+ E K + A+ E + ++ LE V + ++K Q +
Sbjct: 1790 D-QSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT 1848
Query: 2975 SQTAENIVREI 2985
Q E ++E+
Sbjct: 1849 CQILEQKIKEL 1859
Score = 38.3 bits (85), Expect = 0.43
Identities = 87/462 (18%), Positives = 189/462 (40%), Gaps = 36/462 (7%)
Query: 733 LMASAATASKSLEIIS-SLINPLSEILSITDTIQ-ESASETIEVQRTLFSRLPKPLKVLQ 790
+ A T K LE ++ S+ + E+ ++ D ++ ESA++ E++R K Q
Sbjct: 1597 MKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKR----------KAEQ 1646
Query: 791 QTLTIIEKCIDVESDNRTLVKKTCVSIMEKCGNAIQNLVSEINAIEKKEYLLLSENVCNE 850
+ I ++ + + KK S + + +Q E++ +E+K L E+ +E
Sbjct: 1647 KIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEK--LKSVESSQSE 1704
Query: 851 LDVVSNEISTVVNFST-ESIKTNNLLNETTEVKLESTVESKHLTDTQKALFELKGPLRSL 909
+V V ++ E + + +T E K+ +V ++LT+ +K L +
Sbjct: 1705 TLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKI--SVLQRNLTEKEKLLQRVGQEKEET 1762
Query: 910 LYIVDSAESGKIVDISQVNNSEVILNDMSASIQDLQSALEQIESLSVLECATSLNKYNTE 969
+ + ++ ++E ++ + I LQ LE+ L A + K E
Sbjct: 1763 VSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK---E 1819
Query: 970 IIENVMEPVLQLRSSFEKMSTEIKAEDKIQLNKVLSSIKE--NLTVISSYINKVENN--I 1025
+N ++ L + F+ + ++ E ++ + IKE + V +++VE
Sbjct: 1820 GGKNNIQAKQNLENVFDDVQKTLQ-EKELTCQILEQKIKELDSCLVRQKEVHRVEMEELT 1878
Query: 1026 GAFDVLQNENKLEALQKMAETLI-SLEKNLPTLDTMPQVQGNMNSFHKNLTKALEKVIES 1084
++ LQ +++ K E L + E+ + P++ NM + H +L L E
Sbjct: 1879 SKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA-ER 1937
Query: 1085 NNANKYLSMIEICDGIRRINS--------CIRDMDTDNILSLASLSNTLKIIQNQFIKNI 1136
++ + +R + ++ D + + L++ N +K +
Sbjct: 1938 EKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 1997
Query: 1137 FDSELNCCVVTNITDILIGIQETINQAQEFTTEIQYDNFQDT 1178
E N + ++ + I+ETIN+AQE E+ + ++T
Sbjct: 1998 M-REFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEET 2038
Score = 37.5 bits (83), Expect = 0.75
Identities = 52/266 (19%), Positives = 112/266 (42%), Gaps = 16/266 (6%)
Query: 839 EYLLLSENVCNELDVVSNEISTVVNFSTESI------KTNNLLNETTEVKLESTVESKHL 892
E+ LSE + +LD+ + ++ T + KTN +L+ + + +T + L
Sbjct: 1205 EFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1264
Query: 893 TDTQKALFELKGPLRSLLYIVDSAESGKIVDISQVNNSEVILNDMSASIQDLQSALE--Q 950
+ EL+ LR L ++ Q+ E + M A I+ L + E Q
Sbjct: 1265 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQ 1324
Query: 951 IESLSVLECATSLNKYNTEIIENVMEPVLQLRSSFEKMSTEIKAEDKIQLNKVLSSIKE- 1009
E + + A+ T++ + + E + ++ M E+K E K++++ + + +
Sbjct: 1325 KEGGNQQQAASEKESCITQLKKELSENI----NAVTLMKEELK-EKKVEISSLSKQLTDL 1379
Query: 1010 NLTVISSY-INKVENNIGAFDVLQNENKLEALQKMAETLISLEK-NLPTLDTMPQVQGNM 1067
N+ + +S +++ E I + +E K E L ++ + ++ + + + QV
Sbjct: 1380 NVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWS 1439
Query: 1068 NSFHKNLTKALEKVIESNNANKYLSM 1093
N F + KA + + N K L +
Sbjct: 1440 NKFSEWKKKAQSRFTQHQNTVKELQI 1465
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 50.0 bits (114), Expect = 1e-04
Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 15/163 (9%)
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF-G 275
+V P + W D PV ++ R + + F + L+ D ++CVA +D G
Sbjct: 54 EVEAPGPVHVYWLLDGAPVQDTERRFA--QGSSLSFAAVDRLQ--DSGTFQCVARDDVTG 109
Query: 276 QSVTSCFLKLIIPRHYKKPRFLEN--LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ S I P L++ +A + + V L C + G P+P +W++DG L
Sbjct: 110 EEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPL 169
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASS 368
G + +S ++ +L G Y+C A + G A SS
Sbjct: 170 SDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSS 212
Score = 50.0 bits (114), Expect = 1e-04
Identities = 69/281 (24%), Positives = 108/281 (38%), Gaps = 41/281 (14%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD------------VYQLTGTNSLG 152
+A + + V+ C + G P P WF+DG L G + G G
Sbjct: 137 EAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSG 196
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
Y C A + GQA SS T+ + +E ++ AP+ V V A+ +E
Sbjct: 197 LYSCCAHSAFGQACSSQNFTL-----SIADESFARVV---LAPQDV-----VVARYEEAM 243
Query: 213 RFTIKVAIPPEPSLLW-YRDDQPVDESSR-CHLGKEERGVF---FLDIQALEFLDQAEWK 267
F + + P PSL W + D+ P+ SR HL + VF L + + + ++
Sbjct: 244 -FHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRAT--VFANGSLLLTQVRPRNAGIYR 300
Query: 268 CVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
C+ G + L + P F + S+E L K G+P+P + W
Sbjct: 301 CIGQGQRGPPII-LEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPK--GLPEPSVWWE 357
Query: 328 KDGEELKP-GDI----HRIISGQDGTCSLGTYTCEASNCMG 363
G L G + H ++ G YTC A+N G
Sbjct: 358 HAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAG 398
Score = 48.0 bits (109), Expect = 5e-04
Identities = 59/255 (23%), Positives = 95/255 (37%), Gaps = 44/255 (17%)
Query: 122 GFPTPVLSWFKDGQELKP-GDVYQL--------TGTNSLGSYCCIAKNCMGQASSSAELT 172
G P P + W G L G VYQ + G Y C A N GQ +T
Sbjct: 348 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNIT 407
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDD 232
V + + L + + QL + P ++ L P+P+++WYR+
Sbjct: 408 VATVPSWLKKPQDSQL--EEGKPGYLDCLTQAT----------------PKPTVVWYRNQ 449
Query: 233 QPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK 292
+ E SR + K L I ++E D ++C++ G ++++ +
Sbjct: 450 MLISEDSRFEVFKNGT----LRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFT 505
Query: 293 KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK-DGEEL------KPGDIHRIISGQ 345
P Q + + + C G +P +KW + DG L G +H +
Sbjct: 506 PP---PQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTR 562
Query: 346 DGTCSLGTYTCEASN 360
D G YTC ASN
Sbjct: 563 D---DAGNYTCIASN 574
>U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4
protein.
Length = 1070
Score = 50.0 bits (114), Expect = 1e-04
Identities = 60/255 (23%), Positives = 95/255 (37%), Gaps = 44/255 (17%)
Query: 122 GFPTPVLSWFKDGQELKP-GDVYQL--------TGTNSLGSYCCIAKNCMGQASSSAELT 172
G P P + W G L G VYQ + G Y C A N GQ +T
Sbjct: 348 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNIT 407
Query: 173 VEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDD 232
V + + L + + QL + P ++ L P+P+++WYR+
Sbjct: 408 VATVPSWLKKPQDSQL--EEGKPGYLDCLTQAT----------------PKPTVVWYRNQ 449
Query: 233 QPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYK 292
+ E SR + K L I ++E D ++C++ G L+++ +
Sbjct: 450 MLISEDSRFEVFKNGT----LRINSVEVYDGTWYRCMSSTPAGSIEAQAVLQVLEKLKFT 505
Query: 293 KPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYK-DGEEL------KPGDIHRIISGQ 345
P Q + + + C G +P +KW + DG L G +H +
Sbjct: 506 PP---PQPQQCMGFDKEATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTR 562
Query: 346 DGTCSLGTYTCEASN 360
D G YTC ASN
Sbjct: 563 D---DAGNYTCIASN 574
Score = 47.6 bits (108), Expect = 7e-04
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 15/163 (9%)
Query: 217 KVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDF-G 275
+V P + W D PV ++ R + + F + L+ D ++CVA +D G
Sbjct: 54 EVEAPGPVHVYWLLDGAPVQDTERRFA--QGSSLSFAAVDPLQ--DSGTFQCVARDDVTG 109
Query: 276 QSVTSCFLKLIIPRHYKKPRFLEN--LQAILSDEGAVNLECKVIGVPQPVLKWYKDGEEL 333
+ S I P L++ +A + + V L C + G P+P +W++DG L
Sbjct: 110 EEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVKLRCHIDGHPRPTYQWFRDGTPL 169
Query: 334 KPGDIHRIISGQDGTCSL--------GTYTCEASNCMGVAASS 368
G + +S ++ +L G Y+C A + A SS
Sbjct: 170 SDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFSQACSS 212
Score = 47.2 bits (107), Expect = 0.001
Identities = 68/281 (24%), Positives = 106/281 (37%), Gaps = 41/281 (14%)
Query: 105 QAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD------------VYQLTGTNSLG 152
+A + + V C + G P P WF+DG L G + G G
Sbjct: 137 EAEIQPQTQVKLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSG 196
Query: 153 SYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDEPF 212
Y C A + QA SS T+ + +E ++ AP+ V V A+ +E
Sbjct: 197 LYSCCAHSAFSQACSSQNFTL-----SIADESFARVV---LAPQDV-----VVARYEEAM 243
Query: 213 RFTIKVAIPPEPSLLW-YRDDQPVDESSR-CHLGKEERGVF---FLDIQALEFLDQAEWK 267
F + + P PSL W + D+ P+ SR HL + VF L + + + ++
Sbjct: 244 -FHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRAT--VFANGSLLLTQVRPRNAGIYR 300
Query: 268 CVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWY 327
C+ G + L + P F + S+E L K G+P+P + W
Sbjct: 301 CIGQGQRGPPII-LEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPK--GLPEPSVWWE 357
Query: 328 KDGEELKP-GDI----HRIISGQDGTCSLGTYTCEASNCMG 363
G L G + H ++ G YTC A+N G
Sbjct: 358 HAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAG 398
>M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 238 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 296
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 297 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 338
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 339 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 396
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 397 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 453
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 454 PVPSVQWLDEDG 465
>M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1
protein.
Length = 1253
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 238 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 296
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 297 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 338
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 339 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 396
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 397 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 453
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 454 PVPSVQWLDEDG 465
>M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 662
Score = 50.0 bits (114), Expect = 1e-04
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 147 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 263
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQPVDESSR-CHLGKEERGV 250
+ + F KV P+P + W + D+ P + + + ++ +
Sbjct: 264 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYAQILKTAGVNTTDKEM 323
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 324 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 382
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 383 GAFLISCMV 391
Score = 46.0 bits (104), Expect = 0.002
Identities = 54/269 (20%), Positives = 108/269 (40%), Gaps = 31/269 (11%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRC 241
N+ P + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 242 HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
K + + + ++ D+ + C+ N++G S+ + ++ R +P L
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLP 262
Query: 302 AILSDEGAVNLE--CKVIGVPQPVLKWYK 328
A + N+E CKV PQP ++W K
Sbjct: 263 ANKTVALGSNVEFMCKVYSDPQPHIQWLK 291
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 148 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
>M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 822
Score = 50.0 bits (114), Expect = 1e-04
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 22/249 (8%)
Query: 86 NSHPTVPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGDVYQL 145
N P P + P ME + V F+C G P P L W K+G+E KP +++
Sbjct: 147 NRMPVAPY-WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
Query: 146 TGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFVHGLKS 203
G ++ I + + + VE+ +N +L + ++ P GL +
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPA 263
Query: 204 VE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQPVDESSR-CHLGKEERGV 250
+ + F KV P+P + W + D+ P + + + ++ +
Sbjct: 264 NKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYAQILKTAGVNTTDKEM 323
Query: 251 FFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQAILSDE 307
L ++ + F D E+ C+A N G S S +L ++ ++P + + L+ I+
Sbjct: 324 EVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEIIIYCT 382
Query: 308 GAVNLECKV 316
GA + C V
Sbjct: 383 GAFLISCMV 391
Score = 46.0 bits (104), Expect = 0.002
Identities = 54/269 (20%), Positives = 108/269 (40%), Gaps = 31/269 (11%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAP--KFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRC 241
N+ P + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 242 HLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQ 301
K + + + ++ D+ + C+ N++G S+ + ++ R +P L
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLP 262
Query: 302 AILSDEGAVNLE--CKVIGVPQPVLKWYK 328
A + N+E CKV PQP ++W K
Sbjct: 263 ANKTVALGSNVEFMCKVYSDPQPHIQWLK 291
Score = 36.7 bits (81), Expect = 1.3
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 284 KLIIPRHYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ + ++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 148 RMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 203
>M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor
receptor protein.
Length = 820
Score = 50.0 bits (114), Expect = 1e-04
Identities = 56/254 (22%), Positives = 102/254 (40%), Gaps = 22/254 (8%)
Query: 82 KMIHNSHPT-VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG 140
K N+ P V + P ME + V F+C G P P L W K+G+E KP
Sbjct: 139 KETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD 198
Query: 141 DVYQLTGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFV 198
+++ G ++ I + + + VE+ +N +L + ++ P
Sbjct: 199 --HRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQ 256
Query: 199 HGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGK 245
GL + + + F KV P+P + W + D+ P V +
Sbjct: 257 AGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNT 316
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQA 302
++ + L ++ + F D E+ C+A N G S S +L ++ ++P + + L+
Sbjct: 317 TDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEI 375
Query: 303 ILSDEGAVNLECKV 316
I+ GA + C V
Sbjct: 376 IIYCTGAFLISCMV 389
Score = 47.6 bits (108), Expect = 7e-04
Identities = 53/267 (19%), Positives = 106/267 (39%), Gaps = 29/267 (10%)
Query: 89 PTVPKNYRKPRFMENLQAVLTEEG-LVSFECKVVGFPTPVLSWFKDGQELKPGDVYQLTG 147
PT+P+ + +++ L G L+ C++ ++W +DG +L + ++TG
Sbjct: 25 PTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRD-DVQSINWLRDGVQLAESNRTRITG 83
Query: 148 TN---------SLGSYCCIAKNCMGQASSSAELTVEDI----------QNQLNEEEKLQL 188
G Y C+ + G ++ + V D + +EE++
Sbjct: 84 EEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDN 143
Query: 189 FSKNQAPKFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLWYRDDQPVDESSRCHL 243
N + + +E K+ P T+K P P P+L W ++ + R
Sbjct: 144 TKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGG 203
Query: 244 GKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLENLQAI 303
K + + + ++ D+ + C+ N++G S+ + ++ R +P L A
Sbjct: 204 YKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVERSPHRPILQAGLPAN 262
Query: 304 LSDEGAVNLE--CKVIGVPQPVLKWYK 328
+ N+E CKV PQP ++W K
Sbjct: 263 KTVALGSNVEFMCKVYSDPQPHIQWLK 289
Score = 36.3 bits (80), Expect = 1.7
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 152 YWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 201
>M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth
factor receptor protein protein.
Length = 731
Score = 50.0 bits (114), Expect = 1e-04
Identities = 56/254 (22%), Positives = 102/254 (40%), Gaps = 22/254 (8%)
Query: 82 KMIHNSHPT-VPKNYRKPRFMENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPG 140
K N+ P V + P ME + V F+C G P P L W K+G+E KP
Sbjct: 50 KETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD 109
Query: 141 DVYQLTGTN-SLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKN-QAPKFV 198
+++ G ++ I + + + VE+ +N +L + ++ P
Sbjct: 110 --HRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQ 167
Query: 199 HGLKSVE-AKIDEPFRFTIKVAIPPEPSLLWYR-----------DDQP-VDESSRCHLGK 245
GL + + + F KV P+P + W + D+ P V +
Sbjct: 168 AGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNT 227
Query: 246 EERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIPRHYKKPRFLEN---LQA 302
++ + L ++ + F D E+ C+A N G S S +L ++ ++P + + L+
Sbjct: 228 TDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWL-TVLEALEERPAVMTSPLYLEI 286
Query: 303 ILSDEGAVNLECKV 316
I+ GA + C V
Sbjct: 287 IIYCTGAFLISCMV 300
Score = 41.9 bits (94), Expect = 0.035
Identities = 35/162 (21%), Positives = 68/162 (41%), Gaps = 8/162 (4%)
Query: 174 EDIQNQLNEEEKLQLFSKNQAPKFVHGLKSVEAKIDE-PFRFTIKVAIP----PEPSLLW 228
+D + +EE++ N + + +E K+ P T+K P P P+L W
Sbjct: 40 DDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRW 99
Query: 229 YRDDQPVDESSRCHLGKEERGVFFLDIQALEFLDQAEWKCVAFNDFGQSVTSCFLKLIIP 288
++ + R K + + + ++ D+ + C+ N++G S+ + ++
Sbjct: 100 LKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG-SINHTYQLDVVE 158
Query: 289 RHYKKPRFLENLQAILSDEGAVNLE--CKVIGVPQPVLKWYK 328
R +P L A + N+E CKV PQP ++W K
Sbjct: 159 RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
Score = 36.3 bits (80), Expect = 1.7
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 290 HYKKPRFLENLQAILSDEGAVNLECKVIGVPQPVLKWYKDGEELKPGDIHRI 341
++ P +E + V +C G P P L+W K+G+E KP HRI
Sbjct: 63 YWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRI 112
>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
Length = 1248
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 233 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRATYQNHNKT 291
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 292 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 333
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 334 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 391
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 392 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 448
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 449 PVPSVQWLDEDG 460
>DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
>DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 50.0 bits (114), Expect = 1e-04
Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 41/252 (16%)
Query: 96 RKPRFM----ENLQAVLTEEGLVSFECKVVGFPTPVLSWFKDGQELKPGD--VYQ----- 144
RKPR + + V + + EC GFPTP + W + + P D YQ
Sbjct: 70 RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKT 128
Query: 145 ----LTGTNSLGSYCCIAKNCMGQASSSAELTVEDIQNQLNEEEKLQLFSKNQAPKFVHG 200
G G Y C+A+N +G A + +TVE AP ++H
Sbjct: 129 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE------------------AAPYWLHK 170
Query: 201 LKSVEAKIDEPFRFTIKVAIPPEPSLLWYRDDQPVDESSRCHLGKEERGVFFLDIQALEF 260
+S E R +V P+P + W + PV+E ++ + +RG L ++
Sbjct: 171 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQP 228
Query: 261 LDQAEWKCVAFNDFGQSVTSCFLKLI-IPRHYKKPRFLENLQAILSDEGAVNLECKVIGV 319
D +C A N G + + ++ ++ +P K +N + L CK G
Sbjct: 229 SDTMVTQCEARNRHGLLLANAYIYVVQLP---AKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 320 PQPVLKWY-KDG 330
P P ++W +DG
Sbjct: 286 PVPSVQWLDEDG 297
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.311 0.128 0.339
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 358,384,968
Number of Sequences: 224733
Number of extensions: 13888642
Number of successful extensions: 53156
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 250
Number of HSP's successfully gapped in prelim test: 819
Number of HSP's that attempted gapping in prelim test: 43248
Number of HSP's gapped (non-prelim): 7500
length of query: 3063
length of database: 73,234,838
effective HSP length: 103
effective length of query: 2960
effective length of database: 50,087,339
effective search space: 148258523440
effective search space used: 148258523440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 74 (33.9 bits)
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