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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= wdV10399
         (600 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P33992 Cluster: DNA replication licensing factor MCM5; ...   134   2e-30
UniRef50_Q21902 Cluster: DNA replication licensing factor mcm-5;...   105   8e-22
UniRef50_A2FUI9 Cluster: MCM2/3/5 family protein; n=1; Trichomon...    75   2e-12
UniRef50_Q4SVP9 Cluster: Chromosome undetermined SCAF13748, whol...    72   9e-12
UniRef50_Q01BJ5 Cluster: Minichromosome maintenance family prote...    65   1e-09
UniRef50_P41389 Cluster: DNA replication licensing factor mcm5; ...    61   2e-08
UniRef50_Q4QAP2 Cluster: Minchromosome maintenance (MCM) complex...    55   1e-06
UniRef50_Q8SRS4 Cluster: DNA REPLICATION LICENSING FACTOR OF THE...    55   1e-06
UniRef50_P29496 Cluster: Minichromosome maintenance protein 5; n...    54   2e-06
UniRef50_UPI000050C0BA Cluster: MCM complex subunit; AAA ATPase;...    53   4e-06
UniRef50_A3ACA9 Cluster: Putative uncharacterized protein; n=2; ...    52   1e-05
UniRef50_Q8WSL5 Cluster: DNA replication licensing factor MCM5; ...    51   2e-05
UniRef50_Q54CP4 Cluster: MCM family protein; n=1; Dictyostelium ...    49   7e-05
UniRef50_A0BS22 Cluster: Chromosome undetermined scaffold_124, w...    49   1e-04
UniRef50_A7AS39 Cluster: DNA replication licensing factor MCM5, ...    48   2e-04
UniRef50_UPI00006CF347 Cluster: MCM2/3/5 family protein; n=1; Te...    47   3e-04
UniRef50_Q4UHR0 Cluster: DNA replication licensing factor (MCM5 ...    47   3e-04
UniRef50_Q8U3I4 Cluster: Cell division control protein 21; n=1; ...    47   3e-04
UniRef50_Q5CJF4 Cluster: DNA replication licensing factor mcm5; ...    46   7e-04
UniRef50_Q9YFR1 Cluster: Minichromosome maintenance protein; n=2...    46   0.001
UniRef50_Q9UYR7 Cluster: MCM inteins containing helicase, minich...    46   0.001
UniRef50_Q7QSR9 Cluster: GLP_714_11088_8896; n=1; Giardia lambli...    44   0.003
UniRef50_Q6R8Y2 Cluster: Minichromosome maintenance protein 5; n...    44   0.004
UniRef50_Q5JIT1 Cluster: DNA replication licensing factor, MCM2/...    42   0.008
UniRef50_Q2NHD8 Cluster: Predicted minichromosome maintenance pr...    39   0.078
UniRef50_UPI00015BB272 Cluster: replicative DNA helicase Mcm; n=...    37   0.32 
UniRef50_Q01GI0 Cluster: Mini-chromosome maintenance protein MCM...    36   0.55 
UniRef50_Q5CTW9 Cluster: DNA replication licensing factor MCM4 l...    36   0.73 
UniRef50_P29469 Cluster: DNA replication licensing factor MCM2; ...    36   0.73 
UniRef50_A0EIN0 Cluster: Chromosome undetermined scaffold_99, wh...    36   0.97 
UniRef50_Q2GYD6 Cluster: Putative uncharacterized protein; n=1; ...    36   0.97 
UniRef50_Q495R6 Cluster: MCM8 protein; n=13; Eumetazoa|Rep: MCM8...    35   1.3  
UniRef50_A3M0C1 Cluster: DNA replication licensing factor, MCM2 ...    35   1.3  
UniRef50_Q9UJA3 Cluster: DNA replication licensing factor MCM8; ...    35   1.3  
UniRef50_A4SAW6 Cluster: Predicted protein; n=1; Ostreococcus lu...    35   1.7  
UniRef50_Q4UDH3 Cluster: Replication licensing factor, putative;...    35   1.7  
UniRef50_Q9HNA5 Cluster: MCM / cell division control protein 21;...    35   1.7  
UniRef50_UPI00004994EB Cluster: DNA replication licensing factor...    34   2.9  
UniRef50_Q4QAH6 Cluster: Putative uncharacterized protein; n=3; ...    34   2.9  
UniRef50_Q17DG5 Cluster: DNA replication licensing factor MCM8; ...    34   2.9  
UniRef50_Q8SS42 Cluster: DNA REPLICATION LICENSING FACTOR MCM2; ...    34   2.9  
UniRef50_Q3IML4 Cluster: ATP-dependent DNA helicase; n=1; Natron...    34   2.9  
UniRef50_A3DNW1 Cluster: MCM family protein; n=1; Staphylothermu...    33   3.9  
UniRef50_UPI00006CCA0D Cluster: MCM2/3/5 family protein; n=1; Te...    33   5.1  
UniRef50_A7PSR8 Cluster: Chromosome chr8 scaffold_29, whole geno...    33   5.1  
UniRef50_A7APV6 Cluster: MCM2/3/5 family protein; n=1; Babesia b...    33   5.1  
UniRef50_Q979U9 Cluster: DNA replication initiator; n=4; Thermop...    33   5.1  
UniRef50_Q235L3 Cluster: MCM2/3/5 family protein; n=1; Tetrahyme...    33   6.8  
UniRef50_Q9UXG1 Cluster: Minichromosome maintenance protein MCM;...    33   6.8  
UniRef50_UPI000049A27A Cluster: DNA replication licensing factor...    32   9.0  
UniRef50_Q1ZXM5 Cluster: MCM family protein; n=2; Dictyostelium ...    32   9.0  
UniRef50_A7AU57 Cluster: DNA replication licensing factor MCM4; ...    32   9.0  
UniRef50_A4HNF5 Cluster: DNA replication factor, putative; n=5; ...    32   9.0  
UniRef50_A2DDL4 Cluster: MCM2/3/5 family protein; n=1; Trichomon...    32   9.0  
UniRef50_Q8ZY88 Cluster: DNA replication licensing factor; n=6; ...    32   9.0  
UniRef50_A3CUX8 Cluster: MCM family protein; n=1; Methanoculleus...    32   9.0  

>UniRef50_P33992 Cluster: DNA replication licensing factor MCM5;
           n=51; Eukaryota|Rep: DNA replication licensing factor
           MCM5 - Homo sapiens (Human)
          Length = 734

 Score =  134 bits (324), Expect = 2e-30
 Identities = 62/86 (72%), Positives = 77/86 (89%)
 Frame = +3

Query: 255 EAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQT 434
           EA V EALRLFQVSTLDAA++G+L+G EGFT++ED EML+R+EKQLKRRFA+GSQVSE +
Sbjct: 634 EADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHS 693

Query: 435 IIQDFLRQKYPERAILKVIHMMIRRG 512
           II+DF +QKYPE AI KV+ +M+RRG
Sbjct: 694 IIKDFTKQKYPEHAIHKVLQLMLRRG 719



 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 41/86 (47%), Positives = 55/86 (63%)
 Frame = +1

Query: 1   AAAGELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPI 180
           A  GE+ L  L+++ AY                    Y++MR+GA QHER +D+R  IPI
Sbjct: 549 AVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPI 608

Query: 181 TVRQLEAIVHISESLAKMQLQPFATK 258
           TVRQLEAIV I+E+L+KM+LQPFAT+
Sbjct: 609 TVRQLEAIVRIAEALSKMKLQPFATE 634


>UniRef50_Q21902 Cluster: DNA replication licensing factor mcm-5;
           n=3; Bilateria|Rep: DNA replication licensing factor
           mcm-5 - Caenorhabditis elegans
          Length = 759

 Score =  105 bits (252), Expect = 8e-22
 Identities = 50/87 (57%), Positives = 66/87 (75%), Gaps = 1/87 (1%)
 Frame = +3

Query: 255 EAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQT 434
           + HV EALRLF+VST++AA TG+LAG EGFT+  D E L R+E Q+K+RFA+G+ VSE  
Sbjct: 658 DKHVEEALRLFRVSTIEAAATGNLAGVEGFTSTADQEALNRIEVQMKKRFAIGTHVSEHL 717

Query: 435 IIQDFL-RQKYPERAILKVIHMMIRRG 512
           I+QDF+ RQ Y E  + KVI  ++RRG
Sbjct: 718 IVQDFVARQHYRESLVKKVIDNLVRRG 744



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
 Frame = +1

Query: 10  GELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHER-QADKRLY---IP 177
           G L +  L+++  Y                    YV MR   +  +  ++ K+ +   IP
Sbjct: 572 GFLTIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRNPVVNADAFKSGKKAHNSAIP 631

Query: 178 ITVRQLEAIVHISESLAKMQLQPFAT 255
           ITVRQLEAIV I+ES+AKM+LQ FAT
Sbjct: 632 ITVRQLEAIVRIAESIAKMELQQFAT 657


>UniRef50_A2FUI9 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
           vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
           vaginalis G3
          Length = 698

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 38/90 (42%), Positives = 60/90 (66%)
 Frame = +3

Query: 249 CDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSE 428
           C E HV EA+RLF+VST +AA TG LA  EG  T+E  + + +V+  + RR  + S+++E
Sbjct: 591 CKEEHVREAIRLFKVSTFNAASTGILA-PEGPMTDEQRQEVNKVQDYINRRCPLSSRINE 649

Query: 429 QTIIQDFLRQKYPERAILKVIHMMIRRGSF 518
             +I + L++K+ + AI++VI  M+ RG F
Sbjct: 650 SALIAE-LKRKFTDFAIVRVIQTMLYRGEF 678



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 20/40 (50%), Positives = 29/40 (72%)
 Frame = +1

Query: 118 LMRTGALQHERQADKRLYIPITVRQLEAIVHISESLAKMQ 237
           L+++  +Q   Q D    IPITVRQLEA++ ++ESLAKM+
Sbjct: 547 LLKSEYVQMRSQIDNTQSIPITVRQLEALIRVTESLAKME 586


>UniRef50_Q4SVP9 Cluster: Chromosome undetermined SCAF13748, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF13748,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 349

 Score = 72.1 bits (169), Expect = 9e-12
 Identities = 35/47 (74%), Positives = 40/47 (85%)
 Frame = +1

Query: 112 YVLMRTGALQHERQADKRLYIPITVRQLEAIVHISESLAKMQLQPFA 252
           YVLMRTGA +HER+ DKR  IPITVRQLEA+V I+ESLAKM+LQ  A
Sbjct: 272 YVLMRTGAREHERETDKRPSIPITVRQLEAVVRIAESLAKMKLQAVA 318



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 21/30 (70%), Positives = 26/30 (86%)
 Frame = +3

Query: 246 VCDEAHVNEALRLFQVSTLDAAMTGSLAGA 335
           V  E  V+EALRLFQVSTLDAA++G+L+GA
Sbjct: 317 VAGEEEVDEALRLFQVSTLDAALSGNLSGA 346


>UniRef50_Q01BJ5 Cluster: Minichromosome maintenance family protein
           / MCM family protein; n=2; Ostreococcus|Rep:
           Minichromosome maintenance family protein / MCM family
           protein - Ostreococcus tauri
          Length = 787

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 37/90 (41%), Positives = 57/90 (63%)
 Frame = +3

Query: 243 TVCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQV 422
           TV  E HV EALRLF+VST+DAA +G +A     + E+  E L  VE Q+K++ A+G+ +
Sbjct: 685 TVVTEEHVQEALRLFEVSTIDAARSG-VADMVVLSAEQ-REELQVVETQIKQKLAIGATM 742

Query: 423 SEQTIIQDFLRQKYPERAILKVIHMMIRRG 512
           S++ +I D  R    E A+ + + +M +RG
Sbjct: 743 SKRHVIDDLARIGVNEWAVTRALLVMTQRG 772



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 28/76 (36%), Positives = 36/76 (47%)
 Frame = +1

Query: 31  LRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQLEAIVH 210
           L+RY  Y                    YV  R   ++  ++      +PITVRQLEAI+ 
Sbjct: 615 LKRYIEYARAVCRPRLSERAMKMLEDSYVRYRE-EMRERKRTGGHAAVPITVRQLEAIIR 673

Query: 211 ISESLAKMQLQPFATK 258
           ISESLAKM LQ   T+
Sbjct: 674 ISESLAKMCLQTVVTE 689


>UniRef50_P41389 Cluster: DNA replication licensing factor mcm5;
           n=20; Dikarya|Rep: DNA replication licensing factor mcm5
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 720

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 34/85 (40%), Positives = 44/85 (51%)
 Frame = +1

Query: 4   AAGELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPIT 183
           A GE+P    RRY  Y                    +V +R    Q E+ ++ R  IPIT
Sbjct: 543 AIGEIPFDKFRRYINYCRHKCAPNLDAEAAEKLSSQFVAIRKLVHQSEQDSNSRSTIPIT 602

Query: 184 VRQLEAIVHISESLAKMQLQPFATK 258
           VRQLEAI+ I+ESLAKM L P A++
Sbjct: 603 VRQLEAIIRITESLAKMSLSPIASE 627



 Score = 40.7 bits (91), Expect = 0.026
 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +3

Query: 234 AVATVCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVG 413
           +++ +  EAH  EA+RLF  STL AA   S          E  E + ++E  L++R  +G
Sbjct: 620 SLSPIASEAHATEAIRLFLTSTLAAATQSS---------PEVTEEVKKIEASLRKRLPIG 670

Query: 414 SQVSEQTIIQDFLR-QKYPERAI 479
            Q S + +I++++    Y + A+
Sbjct: 671 FQASYRMLIREYVNGHGYSQHAL 693


>UniRef50_Q4QAP2 Cluster: Minchromosome maintenance (MCM) complex
           subunit, putative; n=5; Trypanosomatidae|Rep:
           Minchromosome maintenance (MCM) complex subunit,
           putative - Leishmania major
          Length = 801

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 29/104 (27%), Positives = 58/104 (55%), Gaps = 3/104 (2%)
 Frame = +3

Query: 207 SYIRITR*DA---VATVCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTR 377
           S +RIT   A   +  +   +   EA++LF+++T+DA  +G    A+   TE   E++ R
Sbjct: 685 SLVRITESMARMRLDVLASRSDAEEAIKLFKIATVDAIKSGV---ADQILTEAQSELVLR 741

Query: 378 VEKQLKRRFAVGSQVSEQTIIQDFLRQKYPERAILKVIHMMIRR 509
           VE+ L+RR A+G+ V    ++ +  R  +  + + + ++ M++R
Sbjct: 742 VEEALRRRVALGATVEHHRLLSELARMGFDSKLVERALYAMVKR 785


>UniRef50_Q8SRS4 Cluster: DNA REPLICATION LICENSING FACTOR OF THE
           MCM FAMILY MCM5; n=1; Encephalitozoon cuniculi|Rep: DNA
           REPLICATION LICENSING FACTOR OF THE MCM FAMILY MCM5 -
           Encephalitozoon cuniculi
          Length = 696

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 32/81 (39%), Positives = 40/81 (49%)
 Frame = +1

Query: 16  LPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQL 195
           +P+ T++RY  Y                    YV  R    Q E+   KR  IPITVRQL
Sbjct: 520 IPIHTIKRYVQYARSKVFPTLSEAASKQLSRYYVNTRKEVRQLEQSTLKRNAIPITVRQL 579

Query: 196 EAIVHISESLAKMQLQPFATK 258
           EAI+ I ESLAKM+L    T+
Sbjct: 580 EAIIRIGESLAKMELSQIVTE 600



 Score = 33.5 bits (73), Expect = 3.9
 Identities = 17/69 (24%), Positives = 35/69 (50%)
 Frame = +3

Query: 237 VATVCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGS 416
           ++ +  E HV EA+RLF+VST++A   G +   EG    +    +  +  +++    +G 
Sbjct: 594 LSQIVTEKHVEEAIRLFKVSTMNAVSQGHM--LEGMVRPDVINHIEEICSRIRLLVPIGG 651

Query: 417 QVSEQTIIQ 443
            +    +I+
Sbjct: 652 SIRYSDLIR 660


>UniRef50_P29496 Cluster: Minichromosome maintenance protein 5;
           n=11; Ascomycota|Rep: Minichromosome maintenance protein
           5 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 775

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 29/89 (32%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
 Frame = +3

Query: 237 VATVCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGS 416
           ++ +  E HV+EA+RLFQ ST+DAA    + G    +     E + R E++LKRR  +G 
Sbjct: 668 LSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSE-IRRFEQELKRRLPIGW 726

Query: 417 QVSEQTIIQDFL-RQKYPERAILKVIHMM 500
             S QT+ ++F+   ++ + A+ K ++ +
Sbjct: 727 STSYQTLRREFVDTHRFSQLALDKALYAL 755



 Score = 53.6 bits (123), Expect = 3e-06
 Identities = 28/80 (35%), Positives = 43/80 (53%)
 Frame = +1

Query: 13  ELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQ 192
           E+ +  ++RY  Y                    +V +R   L +E ++ +R  IPIT+RQ
Sbjct: 593 EISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQ 652

Query: 193 LEAIVHISESLAKMQLQPFA 252
           LEAI+ I+ESLAK++L P A
Sbjct: 653 LEAIIRITESLAKLELSPIA 672


>UniRef50_UPI000050C0BA Cluster: MCM complex subunit; AAA ATPase;
           n=1; Schizosaccharomyces pombe 972h-|Rep: MCM complex
           subunit; AAA ATPase - Schizosaccharomyces pombe 972h-
          Length = 276

 Score = 53.2 bits (122), Expect = 4e-06
 Identities = 26/49 (53%), Positives = 35/49 (71%)
 Frame = +1

Query: 112 YVLMRTGALQHERQADKRLYIPITVRQLEAIVHISESLAKMQLQPFATK 258
           +V +R    Q E+ ++ R  IPITVRQLEAI+ I+ESLAKM L P A++
Sbjct: 135 FVAIRKRVHQSEQDSNSRSTIPITVRQLEAIIRITESLAKMSLSPIASE 183



 Score = 41.1 bits (92), Expect = 0.019
 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = +3

Query: 234 AVATVCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVG 413
           +++ +  EAH  EA+RLF  STL AA   S          E  E + ++E  L++R  +G
Sbjct: 176 SLSPIASEAHATEAIRLFLTSTLAAATQSS---------PEVTEEVKKIEASLRKRLPIG 226

Query: 414 SQVSEQTIIQDFLR-QKYPERAILKVIHMM 500
            Q S + +I++++    Y + A+   + ++
Sbjct: 227 FQASYRMLIREYVNGHGYSQHALEMALQIL 256


>UniRef50_A3ACA9 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 714

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 30/91 (32%), Positives = 51/91 (56%)
 Frame = +3

Query: 237 VATVCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGS 416
           + +V    HV EA RLF VST+DAA +G +      + +  +E + + E Q+KRR  +GS
Sbjct: 610 LTSVATPEHVEEAFRLFNVSTVDAARSG-INEHLNLSPDIANE-IKQAEAQIKRRMGIGS 667

Query: 417 QVSEQTIIQDFLRQKYPERAILKVIHMMIRR 509
            +SE+ +I +  R    E  + + + +M +R
Sbjct: 668 HISERRLIDELNRMGMNESIVRRALLIMHQR 698



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/48 (50%), Positives = 30/48 (62%)
 Frame = +1

Query: 112 YVLMRTGALQHERQADKRLYIPITVRQLEAIVHISESLAKMQLQPFAT 255
           + L  T   Q   +  +   IPITVRQLEAI+ +SESLAKM+L   AT
Sbjct: 568 FSLSLTKMRQQAHETGRAAAIPITVRQLEAIIRLSESLAKMRLTSVAT 615


>UniRef50_Q8WSL5 Cluster: DNA replication licensing factor MCM5;
           n=9; Plasmodium|Rep: DNA replication licensing factor
           MCM5 - Plasmodium falciparum
          Length = 758

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 30/82 (36%), Positives = 40/82 (48%)
 Frame = +1

Query: 10  GELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVR 189
           GE+PL+ L RY  Y                    YV  R       R   K+  IPIT+R
Sbjct: 583 GEIPLSKLTRYIQYAKREIAPLLSKEARDSLRNFYVQTRAEYRGDRRSVTKK--IPITLR 640

Query: 190 QLEAIVHISESLAKMQLQPFAT 255
           QLE+++ ++ES AKM+L  FAT
Sbjct: 641 QLESLIRLAESFAKMELSQFAT 662


>UniRef50_Q54CP4 Cluster: MCM family protein; n=1; Dictyostelium
           discoideum AX4|Rep: MCM family protein - Dictyostelium
           discoideum AX4
          Length = 757

 Score = 49.2 bits (112), Expect = 7e-05
 Identities = 26/41 (63%), Positives = 31/41 (75%)
 Frame = +1

Query: 133 ALQHERQADKRLYIPITVRQLEAIVHISESLAKMQLQPFAT 255
           +++ ER+  K   IPITVRQLEAI+ ISESLAKM L P AT
Sbjct: 619 SVETERKKRKNA-IPITVRQLEAIIRISESLAKMSLSPIAT 658



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 27/95 (28%), Positives = 43/95 (45%)
 Frame = +3

Query: 234 AVATVCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVG 413
           +++ +    H  EA+RLF +ST DA  T +        T E  E +   EK LK R  +G
Sbjct: 652 SLSPIATNEHAKEAIRLFDISTFDAITTNNTVNET--LTPERLENIRTAEKYLKDRVPIG 709

Query: 414 SQVSEQTIIQDFLRQKYPERAILKVIHMMIRRGSF 518
           S +  + +     R       ILK + +++ R  F
Sbjct: 710 SSIRIKDVRFQLSRSGLDHFTILKAVDILVGRDEF 744


>UniRef50_A0BS22 Cluster: Chromosome undetermined scaffold_124,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_124,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 732

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
 Frame = +3

Query: 255 EAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEED-HEMLTRVEKQLKRRFAVGSQVSEQ 431
           E HV EA RLFQ+ST+ A   GS     G     D  +++ ++E+ + RR ++GS++   
Sbjct: 633 EEHVKEAHRLFQISTMMAVSLGSKEF--GLDLSNDLKQLVAKIEESILRRISIGSKLPAN 690

Query: 432 TIIQDFLRQKYPERAILKVIHMMIR 506
            +IQ+   +   +RA+   IH +I+
Sbjct: 691 RLIQELSDRFNNQRAVEFAIHNLIQ 715



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 22/33 (66%), Positives = 27/33 (81%)
 Frame = +1

Query: 142 HERQADKRLYIPITVRQLEAIVHISESLAKMQL 240
           H  ++  + +IPITVRQLEAI+ ISESLAKMQL
Sbjct: 595 HHSKSGGKSHIPITVRQLEAIIRISESLAKMQL 627


>UniRef50_A7AS39 Cluster: DNA replication licensing factor MCM5,
           putative; n=1; Babesia bovis|Rep: DNA replication
           licensing factor MCM5, putative - Babesia bovis
          Length = 777

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/81 (34%), Positives = 41/81 (50%)
 Frame = +1

Query: 16  LPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQL 195
           +P+  LRR   Y                    YV  R    + +R A K+  IPIT+RQL
Sbjct: 602 IPMMKLRRLIQYAKQAVSPMLSSDAKDTLRNFYVQKRREYREDKRNATKK--IPITLRQL 659

Query: 196 EAIVHISESLAKMQLQPFATK 258
           E++V I+ES A+M+L P +T+
Sbjct: 660 ESLVRIAESFARMELSPISTE 680


>UniRef50_UPI00006CF347 Cluster: MCM2/3/5 family protein; n=1;
           Tetrahymena thermophila SB210|Rep: MCM2/3/5 family
           protein - Tetrahymena thermophila SB210
          Length = 730

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 29/81 (35%), Positives = 42/81 (51%)
 Frame = +1

Query: 13  ELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQ 192
           E+ L  LR+Y +Y                    YV  R  +  ++  + K+ +IPITVRQ
Sbjct: 553 EIELNLLRKYISYARAKIHPRLTERSAQKIQNLYVEDRKQS--NQGHSSKKHHIPITVRQ 610

Query: 193 LEAIVHISESLAKMQLQPFAT 255
           LEAI+ +SES+AK+QL    T
Sbjct: 611 LEAIIRLSESIAKIQLSEEVT 631



 Score = 35.5 bits (78), Expect = 0.97
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
 Frame = +3

Query: 246 VCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVS 425
           V DE H+N+A  LFQ ST++A   G   G E    +E   +  ++E+ ++    V  +  
Sbjct: 630 VTDE-HINKAHELFQNSTMNAIQNGKELGLE--LPQELQSLCFKIEESIRHNIPVNGRY- 685

Query: 426 EQTIIQDFLRQKYPE-RAILKVIHMMIRRG 512
           + T ++D L  K+   RA+    + +I+ G
Sbjct: 686 DFTSLKDKLFSKFNNARAVDYAFYKLIKDG 715


>UniRef50_Q4UHR0 Cluster: DNA replication licensing factor (MCM5
           homologue), putative; n=2; Theileria|Rep: DNA
           replication licensing factor (MCM5 homologue), putative
           - Theileria annulata
          Length = 770

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 28/83 (33%), Positives = 42/83 (50%)
 Frame = +1

Query: 10  GELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVR 189
           G +    LRR+  Y                    YV  R    + +R + K+  IPIT+R
Sbjct: 617 GPISNNKLRRFIQYSKQVVSPILSNEAKDSLRNFYVQKRKEYREDKRSSTKK--IPITLR 674

Query: 190 QLEAIVHISESLAKMQLQPFATK 258
           QLE++V +SESLA+M+L P A++
Sbjct: 675 QLESLVRVSESLARMELSPIASE 697


>UniRef50_Q8U3I4 Cluster: Cell division control protein 21; n=1;
            Pyrococcus furiosus|Rep: Cell division control protein 21
            - Pyrococcus furiosus
          Length = 1049

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 27/84 (32%), Positives = 41/84 (48%)
 Frame = +1

Query: 7    AGELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITV 186
            A ++P   LR+Y AY                    YV MR    + + + +    IPIT 
Sbjct: 863  APKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITA 922

Query: 187  RQLEAIVHISESLAKMQLQPFATK 258
            RQLEA++ +SE+ A+M+L P  T+
Sbjct: 923  RQLEALIRLSEAHARMRLSPIVTR 946


>UniRef50_Q5CJF4 Cluster: DNA replication licensing factor mcm5;
           n=2; Cryptosporidium|Rep: DNA replication licensing
           factor mcm5 - Cryptosporidium hominis
          Length = 793

 Score = 46.0 bits (104), Expect = 7e-04
 Identities = 25/50 (50%), Positives = 34/50 (68%), Gaps = 1/50 (2%)
 Frame = +1

Query: 112 YVLMRTGALQHERQADK-RLYIPITVRQLEAIVHISESLAKMQLQPFATK 258
           YV +R    +   +A K R+ IPITVRQLEAI  I+ES AKM++Q  A++
Sbjct: 647 YVKIREDNREDTNKASKDRIPIPITVRQLEAITRIAESFAKMEMQNIASE 696



 Score = 37.1 bits (82), Expect = 0.32
 Identities = 23/89 (25%), Positives = 44/89 (49%)
 Frame = +3

Query: 246 VCDEAHVNEALRLFQVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVS 425
           +  E HV  A++LF+ +T++A  +  L       TE+    +   E  +K R  V ++  
Sbjct: 693 IASEKHVEMAIKLFKNATIEAIKSNILLLDNLSPTEQ--SAIIDAEVAIKNRIPVKARAG 750

Query: 426 EQTIIQDFLRQKYPERAILKVIHMMIRRG 512
           + TII+D     Y    + K + ++I++G
Sbjct: 751 KATIIKDLALIGYDPYYLSKAMKILIQKG 779


>UniRef50_Q9YFR1 Cluster: Minichromosome maintenance protein; n=2;
           Desulfurococcales|Rep: Minichromosome maintenance
           protein - Aeropyrum pernix
          Length = 697

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 27/82 (32%), Positives = 41/82 (50%)
 Frame = +1

Query: 13  ELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQ 192
           E+    LR+Y A+                    YV MR+ AL H  Q   +  +PIT RQ
Sbjct: 510 EIDPDLLRKYIAFARKHVKPRLTPQAKKLLKDFYVEMRSSALHHSSQEGAKP-VPITTRQ 568

Query: 193 LEAIVHISESLAKMQLQPFATK 258
           LEA++ ++E+ A+M L+  AT+
Sbjct: 569 LEALIRLTEAHARMSLKQEATE 590


>UniRef50_Q9UYR7 Cluster: MCM inteins containing helicase,
            minichromosome maintenance protein; n=2; Pyrococcus|Rep:
            MCM inteins containing helicase, minichromosome
            maintenance protein - Pyrococcus abyssi
          Length = 1112

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 27/82 (32%), Positives = 39/82 (47%)
 Frame = +1

Query: 13   ELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQ 192
            ++P   LR+Y AY                    YV MR    +   +  K   IPIT RQ
Sbjct: 930  KIPHDLLRKYIAYARKNVHPVISEEAMEEIEKYYVKMRKSVKKSSEEEIKP--IPITARQ 987

Query: 193  LEAIVHISESLAKMQLQPFATK 258
            LEA++ +SE+ A+M+L P  T+
Sbjct: 988  LEALIRLSEAHARMRLSPIVTR 1009


>UniRef50_Q7QSR9 Cluster: GLP_714_11088_8896; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_714_11088_8896 - Giardia lamblia
           ATCC 50803
          Length = 730

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +1

Query: 31  LRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQLEAIVH 210
           L++Y AY                    Y+  R  AL++         IPITVRQLEA++ 
Sbjct: 568 LKKYIAYAQATCTPKLDQSSLEILKAAYIRYRADALKNSSA------IPITVRQLEALIR 621

Query: 211 ISESLAKMQLQPFAT 255
           +SES AKM+L P  T
Sbjct: 622 LSESFAKMRLSPVVT 636


>UniRef50_Q6R8Y2 Cluster: Minichromosome maintenance protein 5; n=2;
           Entamoeba histolytica|Rep: Minichromosome maintenance
           protein 5 - Entamoeba histolytica
          Length = 639

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 26/74 (35%), Positives = 36/74 (48%)
 Frame = +1

Query: 31  LRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQLEAIVH 210
           L+ Y AY                    +V +R    +++ + D    IPITVRQLEAI+ 
Sbjct: 532 LKEYIAYCKAYCIPRLTENASNKLSNYFVSIRQKVRENKLENDNDEGIPITVRQLEAIIR 591

Query: 211 ISESLAKMQLQPFA 252
           ISE+LAKM +   A
Sbjct: 592 ISEALAKMTMSDIA 605



 Score = 33.5 bits (73), Expect = 3.9
 Identities = 12/26 (46%), Positives = 23/26 (88%)
 Frame = +3

Query: 237 VATVCDEAHVNEALRLFQVSTLDAAM 314
           ++ + DE HV+EA+RLF++ST+++A+
Sbjct: 601 MSDIADENHVDEAIRLFELSTMNSAV 626


>UniRef50_Q5JIT1 Cluster: DNA replication licensing factor, MCM2/3/5
            family; n=3; Thermococcus kodakarensis KOD1|Rep: DNA
            replication licensing factor, MCM2/3/5 family -
            Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
          Length = 1157

 Score = 42.3 bits (95), Expect = 0.008
 Identities = 26/86 (30%), Positives = 40/86 (46%)
 Frame = +1

Query: 1    AAAGELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPI 180
            A   ++P   L++Y AY                    YV MR G  + +    +   IPI
Sbjct: 970  AVTPKIPYDLLKKYIAYARKNVHPVLSREAMEEIKRYYVKMRKGLRRGDEDGVQP--IPI 1027

Query: 181  TVRQLEAIVHISESLAKMQLQPFATK 258
            T RQLEA++ +SE+ A+M+L    T+
Sbjct: 1028 TARQLEALIRLSEAHARMRLSETVTR 1053


>UniRef50_Q2NHD8 Cluster: Predicted minichromosome maintenance
           protein; n=3; Methanobacteriaceae|Rep: Predicted
           minichromosome maintenance protein - Methanosphaera
           stadtmanae (strain DSM 3091)
          Length = 670

 Score = 39.1 bits (87), Expect = 0.078
 Identities = 23/70 (32%), Positives = 35/70 (50%)
 Frame = +1

Query: 31  LRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQLEAIVH 210
           +R+Y AY                    YV MR+GA+  E        +PIT RQLEA+V 
Sbjct: 496 MRKYIAYARKSVQPTLTKEAAEVLQDFYVTMRSGAIDEESP------VPITARQLEALVR 549

Query: 211 ISESLAKMQL 240
           ++E+ A+++L
Sbjct: 550 LAEASARIRL 559


>UniRef50_UPI00015BB272 Cluster: replicative DNA helicase Mcm; n=1;
           Ignicoccus hospitalis KIN4/I|Rep: replicative DNA
           helicase Mcm - Ignicoccus hospitalis KIN4/I
          Length = 689

 Score = 37.1 bits (82), Expect = 0.32
 Identities = 24/77 (31%), Positives = 36/77 (46%)
 Frame = +1

Query: 13  ELPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQ 192
           E+P   L++Y AY                    +V +R  A ++         +PIT RQ
Sbjct: 509 EIPADLLKKYIAYARKSVKPKLSEAAARIIENFFVDLRKTAAENPEMG-----VPITARQ 563

Query: 193 LEAIVHISESLAKMQLQ 243
           LEA+V +SE+ AKM L+
Sbjct: 564 LEALVRMSEAHAKMALR 580


>UniRef50_Q01GI0 Cluster: Mini-chromosome maintenance protein MCM6;
           n=2; Ostreococcus|Rep: Mini-chromosome maintenance
           protein MCM6 - Ostreococcus tauri
          Length = 873

 Score = 36.3 bits (80), Expect = 0.55
 Identities = 22/41 (53%), Positives = 27/41 (65%)
 Frame = +1

Query: 112 YVLMRTGALQHERQADKRLYIPITVRQLEAIVHISESLAKM 234
           YV +RTG  Q   Q   R    ITVRQLEAIV +SE+LA++
Sbjct: 614 YVKLRTGDSQPGTQTAYR----ITVRQLEAIVRLSEALARL 650


>UniRef50_Q5CTW9 Cluster: DNA replication licensing factor MCM4 like
           AAA+ ATpase; n=2; Cryptosporidium|Rep: DNA replication
           licensing factor MCM4 like AAA+ ATpase - Cryptosporidium
           parvum Iowa II
          Length = 896

 Score = 35.9 bits (79), Expect = 0.73
 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
 Frame = +1

Query: 28  TLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRT-GALQHERQADKRLYIPITVRQLEAI 204
           TL RY +Y                    Y+ MR  G+     Q  K   I  T RQLE++
Sbjct: 706 TLSRYISYCRQNCNPKLSTDACNKLVQNYISMRRQGSTGGSLQRQKT--ITATPRQLESL 763

Query: 205 VHISESLAKMQLQPFATK 258
           + ISESLA+M+L  +  K
Sbjct: 764 IRISESLARMELSEWVKK 781


>UniRef50_P29469 Cluster: DNA replication licensing factor MCM2;
           n=17; Ascomycota|Rep: DNA replication licensing factor
           MCM2 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 868

 Score = 35.9 bits (79), Expect = 0.73
 Identities = 16/27 (59%), Positives = 21/27 (77%)
 Frame = +1

Query: 175 PITVRQLEAIVHISESLAKMQLQPFAT 255
           PITVR LE+I+ I+ES AKM+L  F +
Sbjct: 804 PITVRHLESILRIAESFAKMRLSEFVS 830


>UniRef50_A0EIN0 Cluster: Chromosome undetermined scaffold_99, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_99,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 805

 Score = 35.5 bits (78), Expect = 0.97
 Identities = 16/38 (42%), Positives = 25/38 (65%)
 Frame = +1

Query: 136 LQHERQADKRLYIPITVRQLEAIVHISESLAKMQLQPF 249
           L+   Q  +R    ITVRQLE+++ +SE+LA++Q   F
Sbjct: 605 LRENDQTSQRTSYRITVRQLESLIRLSEALARVQCDDF 642


>UniRef50_Q2GYD6 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 850

 Score = 35.5 bits (78), Expect = 0.97
 Identities = 15/27 (55%), Positives = 20/27 (74%)
 Frame = +1

Query: 175 PITVRQLEAIVHISESLAKMQLQPFAT 255
           PITVR LEAI+ ISE+  +M+L  + T
Sbjct: 762 PITVRHLEAIIRISEAFCRMRLSEYCT 788


>UniRef50_Q495R6 Cluster: MCM8 protein; n=13; Eumetazoa|Rep: MCM8
           protein - Homo sapiens (Human)
          Length = 880

 Score = 35.1 bits (77), Expect = 1.3
 Identities = 15/41 (36%), Positives = 29/41 (70%)
 Frame = +1

Query: 136 LQHERQADKRLYIPITVRQLEAIVHISESLAKMQLQPFATK 258
           L+  +Q+ +    PIT RQLE+++ ++E+ A+++L+  ATK
Sbjct: 734 LELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATK 774


>UniRef50_A3M0C1 Cluster: DNA replication licensing factor, MCM2
           component; n=8; Eukaryota|Rep: DNA replication licensing
           factor, MCM2 component - Pichia stipitis (Yeast)
          Length = 859

 Score = 35.1 bits (77), Expect = 1.3
 Identities = 15/28 (53%), Positives = 22/28 (78%)
 Frame = +1

Query: 175 PITVRQLEAIVHISESLAKMQLQPFATK 258
           PITVR LE+I+ I+E+ AKM+L  F ++
Sbjct: 792 PITVRHLESILRIAEAFAKMRLSDFVSQ 819


>UniRef50_Q9UJA3 Cluster: DNA replication licensing factor MCM8;
           n=35; Deuterostomia|Rep: DNA replication licensing
           factor MCM8 - Homo sapiens (Human)
          Length = 840

 Score = 35.1 bits (77), Expect = 1.3
 Identities = 15/41 (36%), Positives = 29/41 (70%)
 Frame = +1

Query: 136 LQHERQADKRLYIPITVRQLEAIVHISESLAKMQLQPFATK 258
           L+  +Q+ +    PIT RQLE+++ ++E+ A+++L+  ATK
Sbjct: 694 LELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATK 734


>UniRef50_A4SAW6 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 755

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 130 GALQHERQADKRLYIPITVRQLEAIVHISESLAKMQL 240
           G ++  R    R  I  T RQLE+++ +SESLA+M+L
Sbjct: 605 GYVEMRRMGGSRKVITATPRQLESLIRLSESLARMRL 641


>UniRef50_Q4UDH3 Cluster: Replication licensing factor, putative;
           n=2; Theileria|Rep: Replication licensing factor,
           putative - Theileria annulata
          Length = 1021

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 18/48 (37%), Positives = 32/48 (66%)
 Frame = +1

Query: 112 YVLMRTGALQHERQADKRLYIPITVRQLEAIVHISESLAKMQLQPFAT 255
           YV +R G +Q  +++     + +TVRQLE++V +SE++AK++   F T
Sbjct: 777 YVELRNGDVQLGKRS-----LRMTVRQLESLVRLSEAVAKLKFSDFVT 819


>UniRef50_Q9HNA5 Cluster: MCM / cell division control protein 21;
           n=1; Halobacterium salinarum|Rep: MCM / cell division
           control protein 21 - Halobacterium salinarium
           (Halobacterium halobium)
          Length = 831

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 23/76 (30%), Positives = 36/76 (47%)
 Frame = +1

Query: 31  LRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQLEAIVH 210
           LR+Y AY                    YV +R+      + AD+   +P+T RQLEAIV 
Sbjct: 658 LRKYIAYARRTCFPTMTPDARQAIEEFYVDLRS------KGADEDAPVPVTARQLEAIVR 711

Query: 211 ISESLAKMQLQPFATK 258
           ++E+ A+++L     K
Sbjct: 712 LAEASARLRLSDSVEK 727


>UniRef50_UPI00004994EB Cluster: DNA replication licensing factor;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA
           replication licensing factor - Entamoeba histolytica
           HM-1:IMSS
          Length = 608

 Score = 33.9 bits (74), Expect = 2.9
 Identities = 15/24 (62%), Positives = 20/24 (83%)
 Frame = +1

Query: 172 IPITVRQLEAIVHISESLAKMQLQ 243
           I  T RQLE+++ ISE+LAKMQL+
Sbjct: 534 ISATTRQLESLIRISEALAKMQLR 557


>UniRef50_Q4QAH6 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 963

 Score = 33.9 bits (74), Expect = 2.9
 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
 Frame = +3

Query: 237 VATVCDEAHVNEALRLFQV-STLDAAMTGSLA-GAEGFTTEEDHEMLTRVEKQLKRRFAV 410
           VA  C +     A R+    +TL AA TG+LA G E    EE+ E++T+  + L+ R+AV
Sbjct: 561 VAPFCAQRRRGFASRVLPAKATLAAADTGALARGGEAADEEEEEEVITQFMEVLRVRYAV 620


>UniRef50_Q17DG5 Cluster: DNA replication licensing factor MCM8;
           n=2; Culicidae|Rep: DNA replication licensing factor
           MCM8 - Aedes aegypti (Yellowfever mosquito)
          Length = 845

 Score = 33.9 bits (74), Expect = 2.9
 Identities = 14/28 (50%), Positives = 22/28 (78%)
 Frame = +1

Query: 172 IPITVRQLEAIVHISESLAKMQLQPFAT 255
           IP+T RQLEA+V ++++ A+M L+  AT
Sbjct: 715 IPVTTRQLEALVRLTQARARMDLESEAT 742


>UniRef50_Q8SS42 Cluster: DNA REPLICATION LICENSING FACTOR MCM2;
           n=1; Encephalitozoon cuniculi|Rep: DNA REPLICATION
           LICENSING FACTOR MCM2 - Encephalitozoon cuniculi
          Length = 780

 Score = 33.9 bits (74), Expect = 2.9
 Identities = 14/23 (60%), Positives = 20/23 (86%)
 Frame = +1

Query: 172 IPITVRQLEAIVHISESLAKMQL 240
           +P+TVR +E+IV ISE+ AKM+L
Sbjct: 645 LPVTVRHVESIVRISEAFAKMRL 667


>UniRef50_Q3IML4 Cluster: ATP-dependent DNA helicase; n=1;
           Natronomonas pharaonis DSM 2160|Rep: ATP-dependent DNA
           helicase - Natronomonas pharaonis (strain DSM 2160 /
           ATCC 35678)
          Length = 1037

 Score = 33.9 bits (74), Expect = 2.9
 Identities = 14/29 (48%), Positives = 23/29 (79%)
 Frame = +1

Query: 172 IPITVRQLEAIVHISESLAKMQLQPFATK 258
           +PIT R+LEA+V ++E+ A+++L   ATK
Sbjct: 905 VPITARKLEALVRLAEASARIRLSDTATK 933


>UniRef50_A3DNW1 Cluster: MCM family protein; n=1; Staphylothermus
            marinus F1|Rep: MCM family protein - Staphylothermus
            marinus (strain ATCC 43588 / DSM 3639 / F1)
          Length = 1047

 Score = 33.5 bits (73), Expect = 3.9
 Identities = 22/75 (29%), Positives = 35/75 (46%)
 Frame = +1

Query: 31   LRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQLEAIVH 210
            L++Y +Y                    YV MR   ++  ++      I +T RQLEA++ 
Sbjct: 870  LKKYISYARRYIRPKLTQEAKKLLLDFYVNMRLSGVKASKEGPPA--IAMTPRQLEALIR 927

Query: 211  ISESLAKMQLQPFAT 255
            +SE+ AKM L+  AT
Sbjct: 928  LSEAHAKMALKTKAT 942


>UniRef50_UPI00006CCA0D Cluster: MCM2/3/5 family protein; n=1;
           Tetrahymena thermophila SB210|Rep: MCM2/3/5 family
           protein - Tetrahymena thermophila SB210
          Length = 797

 Score = 33.1 bits (72), Expect = 5.1
 Identities = 16/28 (57%), Positives = 20/28 (71%)
 Frame = +1

Query: 172 IPITVRQLEAIVHISESLAKMQLQPFAT 255
           I  T RQLE+++ ISESLAKM+L    T
Sbjct: 648 ITSTTRQLESLIRISESLAKMKLSDQVT 675


>UniRef50_A7PSR8 Cluster: Chromosome chr8 scaffold_29, whole genome
           shotgun sequence; n=3; Magnoliophyta|Rep: Chromosome
           chr8 scaffold_29, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 741

 Score = 33.1 bits (72), Expect = 5.1
 Identities = 23/76 (30%), Positives = 34/76 (44%)
 Frame = +1

Query: 16  LPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQL 195
           LP   LR+Y AY                    Y+ +R     H   AD     PIT RQL
Sbjct: 567 LPAPLLRKYIAYARTFVFPRMSKPAAEILQKFYLRLR----DHSTSADGT---PITARQL 619

Query: 196 EAIVHISESLAKMQLQ 243
           E++V ++E+ A++ L+
Sbjct: 620 ESLVRLAEARARLDLR 635


>UniRef50_A7APV6 Cluster: MCM2/3/5 family protein; n=1; Babesia
           bovis|Rep: MCM2/3/5 family protein - Babesia bovis
          Length = 918

 Score = 33.1 bits (72), Expect = 5.1
 Identities = 17/46 (36%), Positives = 30/46 (65%)
 Frame = +1

Query: 112 YVLMRTGALQHERQADKRLYIPITVRQLEAIVHISESLAKMQLQPF 249
           YV +R G  Q  +++     + ITVRQLE++V +SE++A+++   F
Sbjct: 693 YVGLRNGDAQSAKRS-----LRITVRQLESLVRLSEAIARLKFSDF 733


>UniRef50_Q979U9 Cluster: DNA replication initiator; n=4;
           Thermoplasmatales|Rep: DNA replication initiator -
           Thermoplasma volcanium
          Length = 699

 Score = 33.1 bits (72), Expect = 5.1
 Identities = 24/75 (32%), Positives = 33/75 (44%)
 Frame = +1

Query: 31  LRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQLEAIVH 210
           LR+Y AY                    YV  RTG+         R  IPITVRQLE+ + 
Sbjct: 531 LRKYVAYAKNNVFPRLSDEAIAILQDQYVRTRTGS---------RDSIPITVRQLESTIR 581

Query: 211 ISESLAKMQLQPFAT 255
           ++E+ A+ +L    T
Sbjct: 582 LAEAAARARLSTIVT 596


>UniRef50_Q235L3 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena
           thermophila SB210|Rep: MCM2/3/5 family protein -
           Tetrahymena thermophila SB210
          Length = 797

 Score = 32.7 bits (71), Expect = 6.8
 Identities = 14/29 (48%), Positives = 22/29 (75%)
 Frame = +1

Query: 172 IPITVRQLEAIVHISESLAKMQLQPFATK 258
           IPIT RQLE++V +S++ AK++ +   TK
Sbjct: 647 IPITNRQLESLVRLSQARAKIECRDIVTK 675


>UniRef50_Q9UXG1 Cluster: Minichromosome maintenance protein MCM;
           n=4; Sulfolobaceae|Rep: Minichromosome maintenance
           protein MCM - Sulfolobus solfataricus
          Length = 686

 Score = 32.7 bits (71), Expect = 6.8
 Identities = 25/81 (30%), Positives = 36/81 (44%)
 Frame = +1

Query: 16  LPLTTLRRYSAYXXXXXXXXXXXXXXXXXXXXYVLMRTGALQHERQADKRLYIPITVRQL 195
           + + TLR+Y AY                    +V MR  + +          I IT RQL
Sbjct: 508 IDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSP-----ILITPRQL 562

Query: 196 EAIVHISESLAKMQLQPFATK 258
           EA++ ISE+ AKM L+   T+
Sbjct: 563 EALIRISEAYAKMALKAEVTR 583


>UniRef50_UPI000049A27A Cluster: DNA replication licensing factor;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA
           replication licensing factor - Entamoeba histolytica
           HM-1:IMSS
          Length = 733

 Score = 32.3 bits (70), Expect = 9.0
 Identities = 12/28 (42%), Positives = 21/28 (75%)
 Frame = +1

Query: 175 PITVRQLEAIVHISESLAKMQLQPFATK 258
           P+T RQLE+++ ++E+ AK + +  ATK
Sbjct: 601 PVTTRQLESLIRLTEARAKAECREIATK 628


>UniRef50_Q1ZXM5 Cluster: MCM family protein; n=2; Dictyostelium
           discoideum|Rep: MCM family protein - Dictyostelium
           discoideum AX4
          Length = 867

 Score = 32.3 bits (70), Expect = 9.0
 Identities = 14/21 (66%), Positives = 19/21 (90%)
 Frame = +1

Query: 178 ITVRQLEAIVHISESLAKMQL 240
           ITVRQLE++V +SESLA++ L
Sbjct: 690 ITVRQLESLVRLSESLARLHL 710


>UniRef50_A7AU57 Cluster: DNA replication licensing factor MCM4;
           n=1; Babesia bovis|Rep: DNA replication licensing factor
           MCM4 - Babesia bovis
          Length = 854

 Score = 32.3 bits (70), Expect = 9.0
 Identities = 13/25 (52%), Positives = 19/25 (76%)
 Frame = +1

Query: 181 TVRQLEAIVHISESLAKMQLQPFAT 255
           T RQLE ++ +S++LAKM+L P  T
Sbjct: 717 TARQLEGLIRLSQALAKMKLSPRVT 741


>UniRef50_A4HNF5 Cluster: DNA replication factor, putative; n=5;
           Trypanosomatidae|Rep: DNA replication factor, putative -
           Leishmania braziliensis
          Length = 916

 Score = 32.3 bits (70), Expect = 9.0
 Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
 Frame = +1

Query: 115 VLMRTGALQHERQADKRL--YIPITVRQLEAIVHISESLAKMQLQPFAT 255
           +L R   +Q +R A   L   +P+TVR LE++V ++++ AK+ LQ   T
Sbjct: 558 LLGRYYEIQRQRGASPSLDDAVPVTVRFLESLVRLAQAHAKLHLQTVCT 606


>UniRef50_A2DDL4 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
           vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
           vaginalis G3
          Length = 754

 Score = 32.3 bits (70), Expect = 9.0
 Identities = 13/21 (61%), Positives = 19/21 (90%)
 Frame = +1

Query: 178 ITVRQLEAIVHISESLAKMQL 240
           ITVRQLEA++ +SE++AK+ L
Sbjct: 591 ITVRQLEALIRLSEAIAKLNL 611


>UniRef50_Q8ZY88 Cluster: DNA replication licensing factor; n=6;
           Thermoproteales|Rep: DNA replication licensing factor -
           Pyrobaculum aerophilum
          Length = 680

 Score = 32.3 bits (70), Expect = 9.0
 Identities = 14/27 (51%), Positives = 20/27 (74%)
 Frame = +1

Query: 172 IPITVRQLEAIVHISESLAKMQLQPFA 252
           I IT RQLEA++ ++ + AKM+L P A
Sbjct: 547 IAITARQLEALIRLTTAEAKMRLSPIA 573


>UniRef50_A3CUX8 Cluster: MCM family protein; n=1; Methanoculleus
           marisnigri JR1|Rep: MCM family protein - Methanoculleus
           marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
          Length = 1059

 Score = 32.3 bits (70), Expect = 9.0
 Identities = 12/23 (52%), Positives = 20/23 (86%)
 Frame = +1

Query: 172 IPITVRQLEAIVHISESLAKMQL 240
           +P+T RQLEA+V ++E+ A+M+L
Sbjct: 926 VPVTARQLEALVRLAEASARMRL 948


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 413,327,262
Number of Sequences: 1657284
Number of extensions: 6415899
Number of successful extensions: 16702
Number of sequences better than 10.0: 56
Number of HSP's better than 10.0 without gapping: 16356
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 16692
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 42317807226
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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