SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= maV30033
         (638 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bo...   173   4e-42
UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Ne...   156   4e-37
UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|R...   154   2e-36
UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxy...   150   2e-35
UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a...   143   3e-33
UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative a...   142   8e-33
UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative a...   141   1e-32
UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxy...   140   3e-32
UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative a...   138   8e-32
UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a...   131   2e-29
UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative a...   131   2e-29
UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative a...   128   8e-29
UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxy...   128   1e-28
UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative a...   126   6e-28
UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxy...   126   6e-28
UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R...   124   2e-27
UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [...   121   1e-26
UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxy...   121   2e-26
UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a...   120   3e-26
UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori...   120   4e-26
UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro...   118   1e-25
UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|...   117   2e-25
UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,...   114   2e-24
UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative a...   107   3e-22
UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG1881...   103   3e-21
UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxy...   101   2e-20
UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophor...    97   4e-19
UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobact...    96   5e-19
UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR...    94   3e-18
UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve...    93   4e-18
UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena...    93   5e-18
UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans...    93   5e-18
UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR...    93   7e-18
UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    92   9e-18
UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ...    92   1e-17
UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam...    91   2e-17
UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O...    90   4e-17
UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gamb...    90   5e-17
UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim...    89   1e-16
UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR...    87   3e-16
UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu...    87   3e-16
UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    87   4e-16
UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit...    86   8e-16
UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR...    86   8e-16
UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta...    85   1e-15
UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:...    85   1e-15
UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    85   1e-15
UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR...    85   1e-15
UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR...    85   2e-15
UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa pr...    84   3e-15
UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b...    83   4e-15
UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc...    83   5e-15
UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR...    83   5e-15
UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophil...    83   5e-15
UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    83   7e-15
UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    83   7e-15
UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill...    82   1e-14
UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=...    82   1e-14
UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte...    81   2e-14
UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Re...    81   2e-14
UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena...    81   3e-14
UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR...    81   3e-14
UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR...    80   4e-14
UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;...    80   4e-14
UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All...    80   5e-14
UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena...    80   5e-14
UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR...    80   5e-14
UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro...    80   5e-14
UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    79   7e-14
UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;...    79   7e-14
UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe...    79   9e-14
UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR...    79   9e-14
UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR...    79   9e-14
UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family memb...    79   9e-14
UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri...    79   1e-13
UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas...    79   1e-13
UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    79   1e-13
UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR...    79   1e-13
UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR...    79   1e-13
UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protei...    79   1e-13
UniRef50_Q28GY1 Cluster: Novel protein containing short chain de...    78   2e-13
UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li...    78   2e-13
UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K...    78   2e-13
UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    78   2e-13
UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR...    78   2e-13
UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR...    78   2e-13
UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom...    78   2e-13
UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho...    78   2e-13
UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR...    78   2e-13
UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=...    78   2e-13
UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR...    77   3e-13
UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR...    77   3e-13
UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; ...    77   3e-13
UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Re...    77   3e-13
UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=...    77   3e-13
UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ...    77   4e-13
UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep...    77   4e-13
UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr...    77   4e-13
UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel...    77   5e-13
UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD...    77   5e-13
UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR...    77   5e-13
UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena...    77   5e-13
UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;...    77   5e-13
UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena...    76   6e-13
UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=...    76   6e-13
UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena...    76   6e-13
UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase...    76   6e-13
UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici...    76   6e-13
UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta...    76   6e-13
UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    76   6e-13
UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    76   6e-13
UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ...    76   8e-13
UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta...    76   8e-13
UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    76   8e-13
UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR...    76   8e-13
UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR...    76   8e-13
UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR...    76   8e-13
UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase fam...    76   8e-13
UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR...    76   8e-13
UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogena...    76   8e-13
UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    76   8e-13
UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p...    75   1e-12
UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc...    75   1e-12
UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    75   1e-12
UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K...    75   1e-12
UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;...    75   1e-12
UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;...    75   1e-12
UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family memb...    75   1e-12
UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n...    75   2e-12
UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivo...    75   2e-12
UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai...    74   3e-12
UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogena...    74   3e-12
UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ...    74   3e-12
UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;...    74   3e-12
UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=...    74   3e-12
UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; ...    74   3e-12
UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative a...    74   3e-12
UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n...    74   3e-12
UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill...    74   3e-12
UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; ...    74   3e-12
UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ...    74   3e-12
UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/redu...    73   4e-12
UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR...    73   4e-12
UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; ...    73   4e-12
UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei...    73   4e-12
UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re...    73   4e-12
UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo...    73   4e-12
UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    73   4e-12
UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc...    73   6e-12
UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    73   6e-12
UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    73   6e-12
UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car...    73   6e-12
UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR...    73   6e-12
UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion...    73   6e-12
UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR...    73   6e-12
UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -...    73   8e-12
UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    73   8e-12
UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec...    73   8e-12
UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena...    73   8e-12
UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specifici...    73   8e-12
UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;...    73   8e-12
UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Myc...    73   8e-12
UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonprote...    72   1e-11
UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba...    72   1e-11
UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac...    72   1e-11
UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh...    72   1e-11
UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap...    72   1e-11
UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    72   1e-11
UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    72   1e-11
UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena...    72   1e-11
UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr...    72   1e-11
UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ...    72   1e-11
UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    72   1e-11
UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP000...    71   2e-11
UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    71   2e-11
UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    71   2e-11
UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ...    71   2e-11
UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    71   2e-11
UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|...    71   2e-11
UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2...    71   2e-11
UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; ...    71   2e-11
UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob...    71   2e-11
UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular or...    71   2e-11
UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU006...    71   2e-11
UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb...    71   2e-11
UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o...    71   3e-11
UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1...    71   3e-11
UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candida...    71   3e-11
UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Pro...    71   3e-11
UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena...    71   3e-11
UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinob...    71   3e-11
UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=...    71   3e-11
UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo...    71   3e-11
UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio...    71   3e-11
UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe...    70   4e-11
UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas...    70   4e-11
UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR...    70   4e-11
UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR...    70   4e-11
UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alterom...    70   4e-11
UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    70   4e-11
UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena...    70   4e-11
UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas...    70   4e-11
UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell...    70   4e-11
UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    70   5e-11
UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici...    70   5e-11
UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid...    70   5e-11
UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR...    70   5e-11
UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinob...    70   5e-11
UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR...    70   5e-11
UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR...    70   5e-11
UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR...    70   5e-11
UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep...    70   5e-11
UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;...    70   5e-11
UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc...    69   7e-11
UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R...    69   7e-11
UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p...    69   7e-11
UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre...    69   7e-11
UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR...    69   7e-11
UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    69   7e-11
UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR...    69   7e-11
UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe...    69   7e-11
UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena...    69   7e-11
UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte...    69   7e-11
UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam...    69   7e-11
UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:...    69   7e-11
UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster...    69   7e-11
UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogena...    69   7e-11
UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella ve...    69   7e-11
UniRef50_Q2UV13 Cluster: Reductases with broad range of substrat...    69   7e-11
UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula...    69   7e-11
UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    69   7e-11
UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n...    69   1e-10
UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena...    69   1e-10
UniRef50_Q1VWP8 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=...    69   1e-10
UniRef50_Q1DDT9 Cluster: Oxidoreductase, short chain dehydrogena...    69   1e-10
UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:...    69   1e-10
UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=...    69   1e-10
UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh...    69   1e-10
UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd...    69   1e-10
UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    69   1e-10
UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyc...    69   1e-10
UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr...    69   1e-10
UniRef50_Q13GX3 Cluster: Putative short-chain dehydrogenase/redu...    69   1e-10
UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac...    69   1e-10
UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;...    69   1e-10
UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_Q9ABX6 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    68   2e-10
UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc...    68   2e-10
UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|...    68   2e-10
UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    68   2e-10
UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    68   2e-10
UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas...    68   2e-10
UniRef50_Q7UJY8 Cluster: Probable short-chain dehydrogenase; n=1...    68   2e-10
UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll...    68   2e-10
UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q0B2G1 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A6T789 Cluster: Putative short-chain dehydrogenase/redu...    68   2e-10
UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    68   2e-10
UniRef50_A1ZK52 Cluster: Dehydrogenase/reductase SDR family memb...    68   2e-10
UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici...    67   3e-10
UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    67   3e-10
UniRef50_Q2SKD5 Cluster: Short-chain dehydrogenase of various su...    67   3e-10
UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ...    67   3e-10
UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_Q54472 Cluster: Oxido-reductase; n=3; Bacteria|Rep: Oxi...    67   3e-10
UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f...    67   3e-10
UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=...    67   3e-10
UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro...    67   3e-10
UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_Q62CL0 Cluster: D-beta-hydroxybutyrate dehydrogenase; n...    67   4e-10
UniRef50_Q3IKU0 Cluster: Putative 3-oxoacyl-[acyl-carrier protei...    67   4e-10
UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati...    67   4e-10
UniRef50_Q1ILJ4 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_Q07KD0 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    67   4e-10
UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    67   4e-10
UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ...    67   4e-10
UniRef50_UPI0000DB6BA4 Cluster: PREDICTED: similar to 3-hydroxya...    66   5e-10
UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)...    66   5e-10
UniRef50_Q930L5 Cluster: Putative; n=3; Proteobacteria|Rep: Puta...    66   5e-10
UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R...    66   5e-10
UniRef50_Q1IP02 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ...    66   5e-10
UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari...    66   5e-10
UniRef50_A5TX02 Cluster: Short-chain alcohol dehydrogenase; n=3;...    66   5e-10
UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_A1ZGN7 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protei...    66   5e-10
UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR...    66   5e-10
UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    66   5e-10
UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano...    66   5e-10
UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    66   7e-10
UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_Q3S8D5 Cluster: Putative short-chain dehydrogenase/redu...    66   7e-10
UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot...    66   7e-10
UniRef50_Q1YQ07 Cluster: Putative uncharacterized protein; n=1; ...    66   7e-10
UniRef50_Q11BT8 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke...    66   7e-10
UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...    66   7e-10
UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms...    66   7e-10
UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth...    66   7e-10
UniRef50_P40747 Cluster: Uncharacterized oxidoreductase yuxG; n=...    66   7e-10
UniRef50_UPI0000518CA5 Cluster: PREDICTED: similar to antdh CG13...    66   9e-10
UniRef50_UPI000050F9D4 Cluster: COG1028: Dehydrogenases with dif...    66   9e-10
UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    66   9e-10
UniRef50_Q8UAB0 Cluster: Dehydrogenase; n=1; Agrobacterium tumef...    66   9e-10
UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    66   9e-10
UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_Q2S467 Cluster: NAD-binding domain 4, putative; n=1; Sa...    66   9e-10
UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    66   9e-10
UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac...    66   9e-10
UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; C...    66   9e-10
UniRef50_A0JVB1 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR...    66   9e-10
UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    66   9e-10
UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;...    66   9e-10
UniRef50_Q7Q3Q2 Cluster: ENSANGP00000007118; n=1; Anopheles gamb...    66   9e-10
UniRef50_Q16Q07 Cluster: Alcohol dehydrogenase, putative; n=1; A...    66   9e-10
UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    65   1e-09
UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    65   1e-09
UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr...    65   1e-09
UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri...    65   1e-09
UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola...    65   1e-09
UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro...    65   1e-09
UniRef50_A1ZL47 Cluster: Oxidoreductase, short chain dehydrogena...    65   1e-09
UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Re...    65   1e-09
UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    65   2e-09
UniRef50_Q73Q46 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    65   2e-09
UniRef50_Q737G7 Cluster: Short chain dehydrogenase family protei...    65   2e-09
UniRef50_Q6MBQ9 Cluster: Putative uncharacterized protein; n=1; ...    65   2e-09
UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena...    65   2e-09
UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=...    65   2e-09
UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho...    65   2e-09
UniRef50_Q1WVR8 Cluster: Short chain dehydrogenase; n=1; Lactoba...    65   2e-09
UniRef50_A7IJL6 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_A6WBU5 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo...    65   2e-09
UniRef50_A1U9L1 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;...    65   2e-09
UniRef50_Q988J7 Cluster: Oxidoreductase, short chain dehydrogena...    64   2e-09
UniRef50_Q8YLL2 Cluster: Alr5286 protein; n=10; Cyanobacteria|Re...    64   2e-09
UniRef50_Q89WX4 Cluster: Short-chain dehydrogenase; n=11; Bradyr...    64   2e-09
UniRef50_Q829D6 Cluster: Putative dehydrogenase; n=2; Streptomyc...    64   2e-09
UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3...    64   2e-09
UniRef50_Q6N3Z0 Cluster: Putative short-chain dehydrogenase/redu...    64   2e-09
UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14...    64   2e-09
UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma...    64   2e-09
UniRef50_Q12B22 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_Q0SJT0 Cluster: Short chain dehydrogenase; n=13; Actino...    64   2e-09
UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_A7NQP2 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc...    64   2e-09
UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ...    64   2e-09
UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2...    64   2e-09
UniRef50_A0TVU3 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;...    64   2e-09
UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1; ...    64   2e-09
UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=...    64   2e-09
UniRef50_P37079 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n...    64   2e-09
UniRef50_Q04520 Cluster: Acetoin(diacetyl) reductase; n=1; Raoul...    64   2e-09
UniRef50_UPI000023CB88 Cluster: hypothetical protein FG04599.1; ...    64   3e-09
UniRef50_Q8UHH7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    64   3e-09
UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter...    64   3e-09
UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyc...    64   3e-09
UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...    64   3e-09
UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep...    64   3e-09
UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh...    64   3e-09
UniRef50_A6X7S0 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter...    64   3e-09
UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bactero...    64   3e-09
UniRef50_A0YCW9 Cluster: Putative 3-oxoacyl-acyl carrier protein...    64   3e-09
UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte...    64   3e-09
UniRef50_A0LJK6 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_Q9SBM0 Cluster: Wts2L; n=3; core eudicotyledons|Rep: Wt...    64   3e-09
UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa...    64   3e-09
UniRef50_Q92A39 Cluster: Lin2083 protein; n=16; Bacilli|Rep: Lin...    64   4e-09
UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R...    64   4e-09
UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill...    64   4e-09
UniRef50_Q7W386 Cluster: Short chain dehydrogenase; n=111; cellu...    64   4e-09
UniRef50_Q6MLJ7 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    64   4e-09
UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ...    64   4e-09
UniRef50_Q5YNA7 Cluster: Putative short chain dehydrogenase; n=1...    64   4e-09
UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR...    64   4e-09
UniRef50_O32291 Cluster: YxnA protein; n=4; Bacteria|Rep: YxnA p...    64   4e-09
UniRef50_Q41CM8 Cluster: Short-chain dehydrogenase/reductase SDR...    64   4e-09
UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ...    64   4e-09
UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena...    64   4e-09
UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu...    64   4e-09
UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR...    64   4e-09
UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR...    64   4e-09
UniRef50_Q0TM71 Cluster: Oxidoreductase, short chain dehydrogena...    64   4e-09
UniRef50_A6W9N2 Cluster: Short-chain dehydrogenase/reductase SDR...    64   4e-09
UniRef50_A3J2Q4 Cluster: Short-chain dehydrogenase; n=2; Flavoba...    64   4e-09
UniRef50_A3ET57 Cluster: Short-chain alcohol dehydrogenase; n=2;...    64   4e-09
UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR...    64   4e-09
UniRef50_A0JVX6 Cluster: Short-chain dehydrogenase/reductase SDR...    64   4e-09
UniRef50_Q75QV9 Cluster: 17-beta hydroxysteroid dehydrogenase; n...    64   4e-09
UniRef50_Q14RS1 Cluster: ABA4 protein; n=4; Pezizomycotina|Rep: ...    64   4e-09
UniRef50_UPI00015B5DCD Cluster: PREDICTED: similar to oxidoreduc...    63   5e-09
UniRef50_UPI00015B452D Cluster: PREDICTED: similar to ENSANGP000...    63   5e-09
UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ...    63   5e-09
UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas...    63   5e-09
UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r...    63   5e-09
UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    63   5e-09
UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ...    63   5e-09
UniRef50_Q5FKH2 Cluster: Oxidoreductase, short chaindehydrogenas...    63   5e-09
UniRef50_Q2IVE1 Cluster: Short-chain dehydrogenase/reductase SDR...    63   5e-09
UniRef50_Q2BDF6 Cluster: Putative uncharacterized protein; n=1; ...    63   5e-09
UniRef50_Q1LG76 Cluster: Short-chain dehydrogenase/reductase SDR...    63   5e-09
UniRef50_Q0YP41 Cluster: Short-chain dehydrogenase/reductase SDR...    63   5e-09
UniRef50_Q0SJP8 Cluster: Short chain dehydrogenase; n=1; Rhodoco...    63   5e-09
UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR...    63   5e-09
UniRef50_A7DJ01 Cluster: Short-chain dehydrogenase/reductase SDR...    63   5e-09
UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentispha...    63   5e-09
UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; ...    63   5e-09
UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=...    63   5e-09
UniRef50_A3HUJ4 Cluster: NAD dependent epimerase/dehydratase fam...    63   5e-09
UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine ...    63   5e-09
UniRef50_A0DCG9 Cluster: Chromosome undetermined scaffold_45, wh...    63   5e-09
UniRef50_Q4P1P4 Cluster: Putative uncharacterized protein; n=1; ...    63   5e-09
UniRef50_Q2UTV6 Cluster: Dehydrogenases with different specifici...    63   5e-09
UniRef50_Q07530 Cluster: Uncharacterized oxidoreductase YDL114W;...    63   5e-09
UniRef50_P16544 Cluster: Putative ketoacyl reductase; n=42; Bact...    63   5e-09
UniRef50_UPI000050F7E5 Cluster: COG1028: Dehydrogenases with dif...    63   6e-09
UniRef50_Q9A3M7 Cluster: Short chain dehydrogenase family protei...    63   6e-09
UniRef50_Q7UMF1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    63   6e-09
UniRef50_Q7ULD3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    63   6e-09
UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    63   6e-09
UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR...    63   6e-09
UniRef50_Q39N07 Cluster: Short-chain dehydrogenase/reductase SDR...    63   6e-09
UniRef50_Q0S7P7 Cluster: Short chain dehydrogenase; n=7; Bacteri...    63   6e-09
UniRef50_Q0RWG5 Cluster: Probable short chain dehydrogenase; n=2...    63   6e-09
UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=...    63   6e-09
UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=...    63   6e-09
UniRef50_A6E9L8 Cluster: Putative uncharacterized protein; n=1; ...    63   6e-09
UniRef50_A6CW76 Cluster: Putative short chain dehydrogenase; n=1...    63   6e-09

>UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1;
           Bombyx mori|Rep: Putative alcohol dehydrogenase - Bombyx
           mori (Silk moth)
          Length = 274

 Score =  173 bits (420), Expect = 4e-42
 Identities = 84/199 (42%), Positives = 126/199 (63%), Gaps = 1/199 (0%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 181
           DKV  +TG A G+G  +V+ LL E  +H+A LD+A+  G +L+ +L  K+G  + KF + 
Sbjct: 14  DKVFLVTGGAAGVGAGLVKALLFENARHVAFLDVADREGAALEAQLIIKFGALRVKFIKC 73

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           DV +E         V+ +   +D VIN+AA+++     + + I++N T  + STLKA++I
Sbjct: 74  DVGDERQLASAYKQVLDKYKRLDGVINSAAVLSVDDNSFNRMIDINFTGTVNSTLKALDI 133

Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541
           MG   GG GG ++N+SS+ AL  +  +P+Y ATK+AVLQFS  +G  E F++T VRVL+V
Sbjct: 134 MGADKGGSGGVIVNISSLLALNLTSHLPVYAATKAAVLQFSIRMGTQEQFTRTKVRVLSV 193

Query: 542 CFGATDTALLTDEKLGTFD 598
           C G TDTA+L    L  FD
Sbjct: 194 CLGPTDTAILYKNNLTKFD 212


>UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2;
           Neoptera|Rep: Putative alcohol dehydrogenase -
           Gryllotalpa orientalis (Oriental mole cricket)
          Length = 266

 Score =  156 bits (379), Expect = 4e-37
 Identities = 79/193 (40%), Positives = 117/193 (60%), Gaps = 1/193 (0%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178
           K K   +TG ATGIG + V+ LL  GV+ +A+ D+ E  G +   +LN ++G  K  F +
Sbjct: 4   KGKYALVTGGATGIGLAYVKELLRHGVQAVAVADLDERKGDNSVKQLNDEFGAGKAIFIK 63

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358
            DVTN++              G+D+VINNA +++DS   ++  I +NVTA+   T  A +
Sbjct: 64  CDVTNKDDLEATFRKAAATFKGLDIVINNAGILDDSR--WETEIAINVTAVARGTWLAFD 121

Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
           +MGK+ GG+GG V+N++S+  L      P+Y ATK AV+  S   G P HF +TGVRVLT
Sbjct: 122 LMGKNKGGRGGVVVNIASILGLQAMAGCPVYVATKHAVVGLSRSFGMPYHFDRTGVRVLT 181

Query: 539 VCFGATDTALLTD 577
           +C G TDT L+++
Sbjct: 182 MCPGVTDTPLISE 194


>UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|Rep:
           Zgc:56585 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 270

 Score =  154 bits (373), Expect = 2e-36
 Identities = 81/208 (38%), Positives = 127/208 (61%), Gaps = 5/208 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178
           KDKV  +TGAA G+G S V IL+  G K +A++D+ +  G+ L+  LN +YG N+ +FY 
Sbjct: 4   KDKVAVVTGAAQGLGRSFVEILMKNGSK-VALIDVNKSLGEELKTNLNKEYGPNRAEFYT 62

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358
           +DV++EE F G+L  +V++ G ID++ NNA ++N+    ++K I +N+  ++  T  A+E
Sbjct: 63  ADVSSEEDFKGVLKKIVEQFGQIDIMCNNAGIINEKH--WEKTIAINLGGVVRGTYLALE 120

Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
            M K +GG GG ++NV+S+A L    V PIY ATK  V+ FS  +      S  GVR+  
Sbjct: 121 YMKKENGGSGGVIVNVASMAGLGPLPVAPIYTATKHGVVGFSRAMAVVSKLSNYGVRINV 180

Query: 539 VCFGATDTALL----TDEKLGTFDKYLE 610
           +C     T+LL    ++E  G+F +  E
Sbjct: 181 LCPWFVKTSLLSLLNSEEHTGSFSQMKE 208


>UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase; n=1; Apis
           mellifera|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase - Apis mellifera
          Length = 266

 Score =  150 bits (364), Expect = 2e-35
 Identities = 76/182 (41%), Positives = 117/182 (64%), Gaps = 1/182 (0%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178
           KDK V ITG A+G+G ++ R LL  G   IA++D AEE+GK     LN ++G N+T FY 
Sbjct: 4   KDKRVIITGVASGLGLTISRELLRNGASIIAMID-AEESGKETVDILNKEFGRNRTIFYH 62

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358
            ++ N   F       V+  GG+++++NNA + N++   + K I+VNVT++I +TL  I+
Sbjct: 63  CNIANNSEFDDTFKKAVKALGGLEILVNNADVTNETD--FMKTIDVNVTSVIRATLLGIQ 120

Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
            M K  GGKGG ++N+SS+A L  +  +P+Y ATK AV+ FS    +P H+ +TGV++L 
Sbjct: 121 QMQKDLGGKGGAIVNISSLAGLYAAPQLPVYSATKHAVVSFSRSFAQPYHYKRTGVKILV 180

Query: 539 VC 544
           +C
Sbjct: 181 MC 182


>UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 261

 Score =  143 bits (347), Expect = 3e-33
 Identities = 71/191 (37%), Positives = 118/191 (61%), Gaps = 1/191 (0%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +KV  ITG A GIG ++V+ LL+ G+K +A+ D+     K + ++L  KYGN+ + Y  D
Sbjct: 5   NKVAIITGGAGGIGAAIVKRLLEHGIKLVALFDLDNSNTKKIFMDLQKKYGNRVELYPCD 64

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK-AIEVNVTALITSTLKAIEI 361
           VTN+  F    + V++    ID+++NNA + +D   I+ +  I++N  A++  +L  IE 
Sbjct: 65  VTNKAQFEENFDKVLKTHKTIDILLNNAGIGSD---IHTELMIDLNYKAVVLGSLLFIER 121

Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541
           +GKH GGKGG ++N +S+  L     +P+Y +TK AV+ F+ C+     +  TGVRV+ +
Sbjct: 122 LGKHKGGKGGIIVNTASILGLRNFDCLPVYCSTKHAVVSFTRCL--DVQYDTTGVRVVAI 179

Query: 542 CFGATDTALLT 574
           C G T+T L++
Sbjct: 180 CPGVTETPLVS 190


>UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 329

 Score =  142 bits (343), Expect = 8e-33
 Identities = 69/195 (35%), Positives = 115/195 (58%), Gaps = 1/195 (0%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178
           KDK   + GA  G+G +  + LL  GV  + ++D+ E  G++    LN ++G N+  F +
Sbjct: 71  KDKKAMVIGACDGLGMAFSKELLRNGVARVLMIDMNETLGRAQADRLNEEFGRNRATFTK 130

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358
            DVT    F       V   G +D+++NNAA++ D +  ++  I+ NVTA+  +++  ++
Sbjct: 131 CDVTKGSEFDACFKDAVNTLGALDIIVNNAAMI-DEVNFHR-TIDTNVTAVFRASMMGVQ 188

Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
            MGK +GGKGG ++NV+SV  L     +PIY AT  AV+ FS    +P H+ +TGVR++ 
Sbjct: 189 QMGKDTGGKGGVIVNVASVLGLEACPQLPIYSATNHAVIAFSRSFSQPYHYQRTGVRLMV 248

Query: 539 VCFGATDTALLTDEK 583
           +C G T++ +L + K
Sbjct: 249 LCPGLTESPMLENLK 263


>UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 279

 Score =  141 bits (341), Expect = 1e-32
 Identities = 75/205 (36%), Positives = 119/205 (58%), Gaps = 1/205 (0%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178
           KDKV+ +TG A GIG   V   L++G +++AILDI  E       +L  ++G ++   Y 
Sbjct: 11  KDKVIIVTGGANGIGLECVLEFLEKGARYVAILDITPE--NFTADKLQEEFGTHRVDLYH 68

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358
            D+ NEE F      V+++   +D++IN+A + N++     + ++VNV   I   L AIE
Sbjct: 69  CDIANEEEFRSNFKKVIEKHNYVDILINDAGVANENDTA--RLLDVNVKGTILGNLMAIE 126

Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
            MGKH GG+GG V+NV+SV  L   HV+P+Y A+K A++ F+  +    +  + GV+++ 
Sbjct: 127 HMGKHKGGRGGVVVNVASVIGLLNCHVLPVYSASKHAIVSFTRSM--KSNCDRLGVKIIA 184

Query: 539 VCFGATDTALLTDEKLGTFDKYLEF 613
           VC G T T L  +  + T   YL+F
Sbjct: 185 VCPGHTRTKLNFELAVETSVNYLDF 209


>UniRef50_UPI0000513348 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase; n=2; Apis
           mellifera|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase - Apis mellifera
          Length = 263

 Score =  140 bits (338), Expect = 3e-32
 Identities = 73/200 (36%), Positives = 116/200 (58%), Gaps = 1/200 (0%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYR 178
           K+K   ITG   G+G    + LL+ G K +A+LD++   G+     L  ++G  K  FY 
Sbjct: 6   KNKTALITGGTVGLGLIYAKRLLENGAKCVALLDLSSSPGQQTVNNLEKEFGKGKAIFYA 65

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358
            DV+N   F  +   VV +  G+D+VINNA + ND    +++ + +NV  +I  +L A +
Sbjct: 66  CDVSNINEFEAVFKKVVNDLNGLDIVINNAGIYNDKK--WEQTMCINVGGVIQGSLLAFD 123

Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
            M K  GGKGGT++N++S+ AL   +  P+Y A+K  VL FS  + R  +++ TG+R+L 
Sbjct: 124 HMSKLKGGKGGTIVNIASIVALDIIYSNPVYCASKHFVLAFSRSLAR--YYNNTGIRILI 181

Query: 539 VCFGATDTALLTDEKLGTFD 598
           +C G T T+LL +    +FD
Sbjct: 182 MCPGVTTTSLLENPLSKSFD 201


>UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 271

 Score =  138 bits (335), Expect = 8e-32
 Identities = 71/199 (35%), Positives = 117/199 (58%), Gaps = 8/199 (4%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 181
           +KV+ ITG   G+G    + LL+ G K +A+ D+ E  G+S   +L+ ++G  +  FY  
Sbjct: 5   NKVIIITGGVGGMGFETAKALLNHGAKFVALFDLTETDGQSAIEKLDKEFGKGRAGFYPG 64

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALI-------TS 340
           D+  +  F    N ++++ G IDV+INNA + N+     ++ + VNV + I       + 
Sbjct: 65  DIVIDSEFEDNFNRIIKDHGSIDVLINNAGIANEQN--IERLVNVNVVSSIDKNILRASQ 122

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
            L A+  MGKH GGKGG ++NV+++  L    ++P Y ATK A++ F+ C+   E+F+ T
Sbjct: 123 ILLALNHMGKHKGGKGGAIVNVNAILGLIDCPILPFYSATKHAIIGFTRCM--KENFATT 180

Query: 521 GVRVLTVCFGATDTALLTD 577
           GVRV++VC G T T L+ +
Sbjct: 181 GVRVMSVCPGVTKTNLIKE 199


>UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=3; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 273

 Score =  131 bits (316), Expect = 2e-29
 Identities = 66/190 (34%), Positives = 116/190 (61%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDKVV ITG  +GIG S+ + +L  G K++A+ ++  E  + +  EL+ +Y ++  FY  
Sbjct: 21  KDKVVVITGGTSGIGLSIAKHMLKNGAKYVALFELDHENSRIVFDELHKQYHDRIGFYPC 80

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           DVT  +      + V++    ID++INNA + +D+    + ++++N+ AL+ ++ K I  
Sbjct: 81  DVTKTDLIYNNFDKVMESHKTIDILINNAGIADDNKP--ELSVDINLKALVVASYKFIAR 138

Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541
           +GKH GGKGG ++N++S+A +  S  +P+Y ATK  V+ F+  +     +  TGVRVL +
Sbjct: 139 IGKHKGGKGGVIVNIASIAGIV-SGFLPVYCATKHGVVGFTRTL--QMSYGLTGVRVLAI 195

Query: 542 CFGATDTALL 571
           C   T+T ++
Sbjct: 196 CPSFTNTPIV 205


>UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 266

 Score =  131 bits (316), Expect = 2e-29
 Identities = 71/193 (36%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQV--ELNSKYG-NKTKF 172
           KDKV  +TG   GIG + V+ LL  G K++AI D+     ++     ++  ++G +K  F
Sbjct: 4   KDKVAIVTGGTGGIGFATVQALLRHGAKYVAIFDLDSMHTRAASCIHKVEEEFGKDKADF 63

Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 352
           Y  DVT +  F    + +V  Q  +D+++N A++ ++    +   I++N+TA++T TL  
Sbjct: 64  YTCDVTIQSEFAARYDEIVGMQRTVDILVNYASIASEPRAHHM--IDINLTAVVTCTLIG 121

Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           I+ MG+H  G+GG ++NV SV  LT S   PIY ATK  V  F+  +   +H+   GVRV
Sbjct: 122 IDRMGRHHNGRGGAIVNVCSVFGLTTSPAFPIYTATKYGVYGFTKSL--KDHYEHLGVRV 179

Query: 533 LTVCFGATDTALL 571
           + VC G T+T+LL
Sbjct: 180 MAVCPGLTETSLL 192


>UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 263

 Score =  128 bits (310), Expect = 8e-29
 Identities = 71/193 (36%), Positives = 115/193 (59%), Gaps = 3/193 (1%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKS-LQVE-LNSKYGN-KTKF 172
           K+KV+ ITG   G+  +  ++LL    ++IA+ D  E+   + LQ++    ++G  +  F
Sbjct: 4   KNKVIIITGGLGGLATATTQVLLKHEPRYIALFDTEEKNSYAELQLKKFEQEFGEGRVGF 63

Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 352
           Y SDV N+  F    + V++    +D++IN A ++ D+    +  I+VN   L+  TL A
Sbjct: 64  YASDVRNQHQFEEKYDQVLKSHKSVDILINLAGILCDADT--ELTIDVNFKGLVFCTLTA 121

Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           I+ MG H GG+GGT+INVSS+  L      P+Y ATK AV+ F+N +    H++KTGVR 
Sbjct: 122 IDKMGIHRGGRGGTIINVSSIVGLMFHEDFPVYVATKHAVVAFTNSL--KSHYAKTGVRA 179

Query: 533 LTVCFGATDTALL 571
           +T+C G T T+++
Sbjct: 180 MTMCPGLTSTSMI 192


>UniRef50_UPI000051334A Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1) isoform 1; n=1; Apis
           mellifera|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1) isoform 1 - Apis
           mellifera
          Length = 264

 Score =  128 bits (309), Expect = 1e-28
 Identities = 62/188 (32%), Positives = 111/188 (59%), Gaps = 1/188 (0%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184
           K+  +TG A GIG    R LL  G K +A+LD+++  G+S   +LN+++G ++  F   D
Sbjct: 6   KIAIVTGGANGIGFCTARKLLRNGAKAVALLDLSDSGGESAAADLNNEFGKDRAIFIACD 65

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364
           V+  E F      V+     +++++N A +M+D+   ++  +++N   ++  T+  +  M
Sbjct: 66  VSKNEQFQESFKKVIDTYETLNILVNIAGIMDDAD--WEIMVDINYKGIVYGTILGLHTM 123

Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544
           GK+ GG GG ++N+SSVA L    + PIY  T+ A++ F+  +    ++ KTG+R+LT+C
Sbjct: 124 GKYKGGNGGIIVNMSSVAGLEGIPIAPIYGGTQYAIVGFTQSL--KHYYEKTGIRMLTIC 181

Query: 545 FGATDTAL 568
            G T TA+
Sbjct: 182 PGLTTTAM 189


>UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 267

 Score =  126 bits (303), Expect = 6e-28
 Identities = 74/199 (37%), Positives = 117/199 (58%), Gaps = 4/199 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKT-K 169
           K+KV  +TG   GIG   V+ L+   ++ +AI+D+ +   EA  +   +LN ++G  + +
Sbjct: 4   KNKVAIVTGGIGGIGLVTVQHLIRSKIQFVAIIDLPKSDSEAAVANLSKLNKEFGKGSYQ 63

Query: 170 FYRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 349
           +Y  D+TN + F  I   V+  +  +D++IN A ++ND+       I VN TA++ S++ 
Sbjct: 64  YYSCDLTNIQEFRAIYEKVIALKKYVDILINAAGILNDNA--MNLCINVNFTAVVNSSMI 121

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           AIE M K  GGKGG V+NV+S+A +      PIY ATK AV+ F+  + +P H    GVR
Sbjct: 122 AIEHMRKDKGGKGGVVVNVASIAGIVDFPYNPIYNATKHAVVAFARSL-KP-HNKIIGVR 179

Query: 530 VLTVCFGATDTALLTDEKL 586
           V+ +C G TDT L+  + L
Sbjct: 180 VVCICPGVTDTGLVAFDHL 198


>UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1) - Tribolium castaneum
          Length = 312

 Score =  126 bits (303), Expect = 6e-28
 Identities = 65/188 (34%), Positives = 107/188 (56%), Gaps = 1/188 (0%)
 Frame = +2

Query: 11  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 187
           V  ITG A GIG ++ R+ L  G+  +A+ D ++E G+    +L  ++G NK  F+  D+
Sbjct: 54  VAIITGGAEGIGLAIARVFLKCGISGLAVADCSKEKGEESIKQLACEFGENKVLFFDGDM 113

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367
           +  + F  +    +     +++V+NNA +MND    ++  +  N++  I  TL  ++ M 
Sbjct: 114 SQSKAFDRVFKETLNHFENVNIVVNNAGVMNDVN--WECQVNTNLSGTIIGTLLGMQYMS 171

Query: 368 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCF 547
           K S G+GGT+INV+S+  L  S   PI+  T+  ++ FS  +G   HF +TGVRV  +C 
Sbjct: 172 KTSLGQGGTIINVASIMGLIPSSGYPIHTLTQFGIVGFSRAIGNLNHFDRTGVRVTALCP 231

Query: 548 GATDTALL 571
           G T+T LL
Sbjct: 232 GLTNTKLL 239


>UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep:
           CG4899-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 278

 Score =  124 bits (299), Expect = 2e-27
 Identities = 64/193 (33%), Positives = 112/193 (58%), Gaps = 1/193 (0%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT-KFYR 178
           + K   +TG A GIG  V + LL  G   +AI+D+ +   +   V+L + +  ++    +
Sbjct: 21  RGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEF--VKLRAAHPTQSVMIIK 78

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358
            DV N++        + +  G ID+V+N A + ND     ++ + VN+  +I STL A+ 
Sbjct: 79  MDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKD--VQRTLLVNLGGIINSTLSALP 136

Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
            MGK +GGKGG V+N+SSV  L    ++P+Y ATK+ ++ F+ C+   +++ ++G++ +T
Sbjct: 137 YMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVT 196

Query: 539 VCFGATDTALLTD 577
           VC GAT T + T+
Sbjct: 197 VCPGATMTDMFTN 209


>UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase
           [NAD+]; n=29; Euteleostomi|Rep: 15-hydroxyprostaglandin
           dehydrogenase [NAD+] - Homo sapiens (Human)
          Length = 266

 Score =  121 bits (292), Expect = 1e-26
 Identities = 65/204 (31%), Positives = 115/204 (56%), Gaps = 2/204 (0%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184
           KV  +TGAA GIG +    LL +G K +A++D   EAG   +  L+ ++   KT F + D
Sbjct: 6   KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364
           V +++        VV   G +D+++NNA + N+    ++K +++N+ ++I+ T   ++ M
Sbjct: 65  VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122

Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544
            K +GG+GG +IN+SS+A L      P+Y A+K  ++ F+       +   +GVR+  +C
Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182

Query: 545 FGATDTALLTD-EKLGTFDKYLEF 613
            G  +TA+L   EK     +Y+E+
Sbjct: 183 PGFVNTAILESIEKEENMGQYIEY 206


>UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase (NAD+), partial;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to 15-hydroxyprostaglandin dehydrogenase (NAD+),
           partial - Strongylocentrotus purpuratus
          Length = 298

 Score =  121 bits (291), Expect = 2e-26
 Identities = 67/193 (34%), Positives = 110/193 (56%), Gaps = 2/193 (1%)
 Frame = +2

Query: 11  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 187
           V  ITGAA G G++    LL   V+ I I+D     GK+ + ELN KYG +K +F++ DV
Sbjct: 46  VALITGAAEGFGKAFTEELLKRSVRGIGIVDFNAAKGKATETELNKKYGEDKVRFFQCDV 105

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367
           ++++      +  ++   GID+V NNA +  D +  ++K ++V++ A++  T  A + M 
Sbjct: 106 SSKDQLEDAFSKTLEHYKGIDIVCNNAGI-GDELN-WEKTVDVDLVAVMRGTFLAKQYMD 163

Query: 368 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEH-FSKTGVRVLTVC 544
           K+ GG+GG VIN++S+A L    + P Y A K  VL FS  +   +  F+   VR+  +C
Sbjct: 164 KNKGGRGGIVINIASMAGLYPMPLAPAYSAAKHGVLGFSRALAIADKVFNPENVRLNCLC 223

Query: 545 FGATDTALLTDEK 583
              ++TA+L   K
Sbjct: 224 PSFSETAILQQMK 236


>UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 337

 Score =  120 bits (289), Expect = 3e-26
 Identities = 62/191 (32%), Positives = 106/191 (55%), Gaps = 1/191 (0%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184
           K V ITG A G+G +     L  G   I I+DI + AGK +    +  +G  K  F  +D
Sbjct: 46  KNVLITGGAAGLGHAFFNHFLQFGANKICIIDIDDVAGKKIVASTDKSHGVGKVIFIHAD 105

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364
           V+     +      V+    +D+V+NNA ++++    +++ I VN+  +I+  L +++ M
Sbjct: 106 VSRHSEIVAGFQKAVKLMDAVDIVVNNAGILDERR--WEREIAVNLNGMISVALLSMQYM 163

Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544
           G+  GG+GG ++NV+    +  +  +P+Y ATK A++  S  +  P +  +TGVRV+T+C
Sbjct: 164 GRDMGGRGGILVNVAEHMDVHCTAQLPVYTATKQAIIGLSQSLAAPCNTERTGVRVITLC 223

Query: 545 FGATDTALLTD 577
            G T+TAL  D
Sbjct: 224 PGLTETALTID 234


>UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx
           mori|Rep: Alcohol dehydrogenase - Bombyx mori (Silk
           moth)
          Length = 289

 Score =  120 bits (288), Expect = 4e-26
 Identities = 77/200 (38%), Positives = 107/200 (53%), Gaps = 3/200 (1%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184
           KVV ITGAA GIG ++    L  G K I ILDI    G     ELN KYG NK +F   D
Sbjct: 34  KVVVITGAAQGIGYAIADNFLKNGAKVIIILDINVPKGIQAAKELNCKYGKNKAEFIECD 93

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364
           +T +     I   + ++   +DV++NNA +  +     +K +  N  A I  +LK +E M
Sbjct: 94  ITKDLE--RISKIIYKKYKYVDVLVNNAGIFKEIKP--RKLLLTNAVATIEFSLKFMENM 149

Query: 365 GKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541
            K    GKGGT+IN++S          P Y  TK A++ FS  +G   ++ K GVRVLT+
Sbjct: 150 RKDKLSGKGGTIINIASTVVHYIDPFFPTYRGTKFAIMGFSRSLGHEYNYKKNGVRVLTI 209

Query: 542 CFGATDTAL-LTDEKLGTFD 598
           C G T+T L L + K+ + D
Sbjct: 210 CPGETNTTLGLDNTKVNSED 229


>UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to
           hydroxyprostaglandin dehydrogenase 15 (NAD); n=2;
           Tribolium castaneum|Rep: PREDICTED: similar to
           hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium
           castaneum
          Length = 479

 Score =  118 bits (284), Expect = 1e-25
 Identities = 61/193 (31%), Positives = 108/193 (55%), Gaps = 2/193 (1%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 181
           +KV  I+GAA+GIG ++ + LL  G++ + I D+ +E G+    E+ +++G+ +  F  +
Sbjct: 7   NKVALISGAASGIGLTIAKELLRNGLRGVTIADVNKELGEKALQEIENEFGSGRAIFVLT 66

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE- 358
           DV++ + F       +     ID+++N A ++NDSI  +++ I +NV   +   L A+E 
Sbjct: 67  DVSSMKSFEDAFQKTINTFKNIDILVNGAGVLNDSI--WQQEIAINVNGTVHGILLALEN 124

Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
            + K+     G ++N SS+A +      PIY  TK A+   +   G   H+ +T VR++ 
Sbjct: 125 YIPKYKTDSEGVIVNFSSIAGVAAFPAFPIYTGTKFAIFGMTKAFGDEAHYERTKVRIMA 184

Query: 539 VCFGATDTALLTD 577
           +C G TDT LL D
Sbjct: 185 ICPGPTDTPLLRD 197



 Score = 93.1 bits (221), Expect = 5e-18
 Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 2/172 (1%)
 Frame = +2

Query: 53  VVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDVTNEEHFLGILNAVV 229
           +VR     G   + I DI  E G+ +  E+ +++G NK  +  +DVT +  +       +
Sbjct: 233 IVRNAPSGGAWGVTIADINTELGEKVLQEIINEFGKNKAIYILTDVTCKNSYEAAFKKTI 292

Query: 230 QEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE-IMGKHSGGKGGTVINV 406
           +    +D+V+N A ++N+    +++ +++N+   +  T+ A+E  + K+  G  G ++N+
Sbjct: 293 ETFQNLDIVVNGAGIVNELD--WQQEVDINLNGTLHGTILALENYIPKYKSGSEGVIVNI 350

Query: 407 SSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCFGATDT 562
           SS A L      PIY  TK AV+  S   G   H+ +T VRVLT C G T+T
Sbjct: 351 SSAAILDCFPPYPIYTGTKFAVMGISKSFGAEVHYKRTKVRVLTACPGVTET 402


>UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4;
           Endopterygota|Rep: ENSANGP00000013280 - Anopheles
           gambiae str. PEST
          Length = 183

 Score =  117 bits (282), Expect = 2e-25
 Identities = 66/183 (36%), Positives = 96/183 (52%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K+KV  +TGAATG+G +    LL  G K + I D+  +AG+    EL  +YG +  F   
Sbjct: 4   KNKVALVTGAATGLGRAFSEELLKHGAK-VVICDLDSDAGELTVEELEKQYGARVLFCHC 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           DVT+   F       V     +++VINNA +MND+   ++  ++VN+   I  TL A + 
Sbjct: 63  DVTDYIQFEEAFEYTVNMFKEVNIVINNAEIMNDNF--WELEVDVNLNGAIRGTLLAQKF 120

Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541
           M K  G  GG ++N+ S  ++T     PIY ATK A+L  +   G P H + T VR    
Sbjct: 121 MDKSKGKGGGVLVNIGSGVSVTPQLSTPIYTATKHAILGLTKACGDPFHHANTNVRAFAY 180

Query: 542 CFG 550
           C G
Sbjct: 181 CPG 183


>UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG4899-PA, isoform A - Tribolium castaneum
          Length = 295

 Score =  114 bits (274), Expect = 2e-24
 Identities = 64/191 (33%), Positives = 98/191 (51%), Gaps = 1/191 (0%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184
           KV  ITG + GIG +V   +L E  K++A++ +    G+     LNS YG NK  F+  D
Sbjct: 52  KVALITGGSDGIGLAVAHEILSENSKNVALIGVDNTKGRESVHALNSTYGRNKAVFFNCD 111

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364
           V ++       N V++E G ID+VIN A + +     ++K I  N+   I  TL+A  +M
Sbjct: 112 VESKVQVNDCFNKVIKEFGSIDIVINAAGVFDGRC--WEKEIMTNLVGTIHCTLEAYRVM 169

Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544
            K   G GG ++N S +  +      P   A+   ++  S   G   +F  TGVRV+T+C
Sbjct: 170 SKDCSGSGGVILNFSGLHGVKPLFPAPTLSASFHGIIGLSRSFGHETNFKTTGVRVVTLC 229

Query: 545 FGATDTALLTD 577
            G T+T  + D
Sbjct: 230 PGITNTNFIKD 240


>UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 268

 Score =  107 bits (256), Expect = 3e-22
 Identities = 63/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIA----EEAGKSLQVELNSKYG-NKTK 169
           +KV  +TG   GIG  +V+  L  G K +AI D+     EE   +L+ +L  ++   +  
Sbjct: 5   NKVGVVTGGLRGIGYVIVQHFLRRGAKFVAIFDLDVEEHEEVVNALK-QLEQEFAAQRFS 63

Query: 170 FYRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 349
           +Y  DVTN + F+   + V    G +D+++NNA +  +        + VN T++I  T+ 
Sbjct: 64  YYCCDVTNFKKFIACYDEVYTTNGAVDILVNNAGVFAEHD--QDLTVAVNFTSVIHCTMH 121

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           AIE MG + GGKGG ++ + S+ AL     +P+Y ATK A+  F       ++ +K GVR
Sbjct: 122 AIERMGTNKGGKGGVIVTIGSICALISLSTIPVYSATKGALACFVR--STKDYNAKYGVR 179

Query: 530 VLTVCFGATDTAL 568
           ++ +C G T T +
Sbjct: 180 IVCLCPGMTKTKM 192


>UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep:
           CG18814-PA - Drosophila melanogaster (Fruit fly)
          Length = 285

 Score =  103 bits (248), Expect = 3e-21
 Identities = 69/217 (31%), Positives = 113/217 (52%), Gaps = 18/217 (8%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 184
           K V   G   GIG+  V+ LL + +K +AI D+  +    L  E   ++ +   FY+  D
Sbjct: 6   KNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVD--DDLLAEWKKQHPDTEIFYQKMD 63

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMND-----SIGIYKKAIEVNVT-------- 325
           +T +        A  ++ G  DVV+N + L++D     +I I    +E+ ++        
Sbjct: 64  ITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVILEIVLSKGFIYQYF 123

Query: 326 ---ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVG 496
               +I STL A+E M K  GG+GG ++N+SSVA L  + +M IY  +K+ V  F+  + 
Sbjct: 124 LKVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMA 183

Query: 497 RPEHFSKTGVRVLTVCFGATDTALLTD-EKLGTFDKY 604
            P H++ +GV  +T+C G T+T +L D +K  TF  Y
Sbjct: 184 SPIHYAHSGVGFITICPGYTNTGILKDIDKKTTFPFY 220


>UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase; n=2; Tribolium
           castaneum|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase - Tribolium
           castaneum
          Length = 255

 Score =  101 bits (241), Expect = 2e-20
 Identities = 59/190 (31%), Positives = 102/190 (53%), Gaps = 1/190 (0%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K KV  +TG A+GIG ++VR LL  G+K ++++DI+E        EL     ++  F ++
Sbjct: 5   KGKVALVTGGASGIGLAMVRELLKNGIKAVSVVDISENT------ELQD---SRVTFIKT 55

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           DVT ++      +  V     +D+V+NNA ++ D I  +K+ I++N+ A+I  T  A+  
Sbjct: 56  DVTCKKQLQAAFDKTVATYNQLDIVVNNAGVI-DEID-WKRTIDINLVAVIEGTYLALRT 113

Query: 362 -MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
            + K+     G ++N +SV  L      PIY  +K  V+     +G P  + +  VR++T
Sbjct: 114 YLPKYKSEAEGVIVNTASVLGLCPLQSAPIYCTSKHGVVGLGRSLGGPHIYDEYKVRIVT 173

Query: 539 VCFGATDTAL 568
           +C G  DT +
Sbjct: 174 ICPGLVDTPM 183


>UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23;
           Schizophora|Rep: Alcohol dehydrogenase - Bactrocera
           oleae (Olive fruit fly)
          Length = 258

 Score = 96.7 bits (230), Expect = 4e-19
 Identities = 59/188 (31%), Positives = 100/188 (53%), Gaps = 2/188 (1%)
 Frame = +2

Query: 11  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSKYGNKTKFYRSD 184
           VVF+ G    IG    + ++ + V    + D+ E A   K+LQ  +N K   K  + + D
Sbjct: 8   VVFVGGLGF-IGYEACKQIMTKNVASFFVFDVLENAENIKALQA-INPK--TKVYYTKFD 63

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364
           +TN+         V+ +   IDV++N A ++ D     +  + +N+  LI +TL+AI +M
Sbjct: 64  ITNKASIKSAFADVIAKVQYIDVLVNGAGILTDPN--VELTMNINLIGLINTTLEAIPLM 121

Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544
            K+  G+GG ++N++SV  L  +    IY A+K  V+ FS  +  P +++ TG+ V T C
Sbjct: 122 DKNKKGRGGLIVNIASVLGLEPAPPAAIYCASKFGVMGFSRSISDPYYYNLTGIAVATFC 181

Query: 545 FGATDTAL 568
            G T+T L
Sbjct: 182 PGLTETPL 189


>UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4;
           Proteobacteria|Rep: Putative dehydrogenase - Azoarcus
           sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 267

 Score = 96.3 bits (229), Expect = 5e-19
 Identities = 65/204 (31%), Positives = 105/204 (51%), Gaps = 10/204 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV +++GAA+GIG ++ R+   EG   + + D+  E G+++   +  + G +  F   DV
Sbjct: 8   KVAYVSGAASGIGAAIARVFAAEGAS-VLLGDVQVERGETVAAHIREQ-GGRALFIHHDV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 349
           ++E  +   L   V+E GG+D+++NNA       L +  +    K + VNV  +I     
Sbjct: 66  SDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAGVILGHKH 125

Query: 350 AIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
           AI  M    S GKGG++IN+SSVA L  +  + +Y ATK AV   S            G+
Sbjct: 126 AIRTMRPGGSAGKGGSIINLSSVAGLIGTPALGVYSATKGAVRLLSKAAAVECGRLGYGI 185

Query: 527 RVLTVCFGATDTAL---LTDEKLG 589
           RV ++  G  DT +   L D+ +G
Sbjct: 186 RVNSIHPGLVDTDMGVKLVDDFVG 209


>UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=10; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium sp. (strain
           JLS)
          Length = 282

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 59/211 (27%), Positives = 106/211 (50%), Gaps = 8/211 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +V  +TG A+GIG  V    + EG K + I D+ +E G++L  +     G    F+ +DV
Sbjct: 12  RVAIVTGGASGIGRGVAERFVAEGAK-VVIADVQDELGEALAEQC----GPNALFHHTDV 66

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTALITST 343
            ++E    +++  V+  G +DV++NNA         L N+ +  + + + VN+ +++  T
Sbjct: 67  GDQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLLSVMAGT 126

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             A   M +H GG   ++IN+SS+  +     +P+Y A+K+A+L F+ C       +   
Sbjct: 127 RDAGRYMSEHGGG---SIINLSSIGGIQAGGGVPVYRASKAAILHFTKCAA--IELAHYD 181

Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLEFF 616
           +RV  +  G   T +L     G   + LE F
Sbjct: 182 IRVNCIAPGNIPTPILQSSATGEDRERLEKF 212


>UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 266

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 61/194 (31%), Positives = 100/194 (51%), Gaps = 7/194 (3%)
 Frame = +2

Query: 11  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 187
           V  +TG   GIG ++ + LLD   K + +LDI E+ G      L+  Y  ++  F + DV
Sbjct: 7   VAIVTGGVQGIGLAISKALLDRDGK-VCMLDINEKTGNETLKLLSENYSKHRVLFIKCDV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM---NDSI--GIYKKAIEVNVTALITSTLKA 352
           T++              G +D++ NNA +    ND +  G +K  I++NV  +I  TL  
Sbjct: 66  TSQPQMEAAFQRTKDVFGRLDILCNNAGIAVRENDLLRSGAWKTIIDINVKGVILGTLLG 125

Query: 353 IEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           ++ MG     G GGT++NV+S+A L  +   P+Y A+K AV+  +  +     ++   VR
Sbjct: 126 LDHMGVSGAKGHGGTIVNVASLAGLVPAPASPVYTASKHAVVGLTRTL--TSLWATECVR 183

Query: 530 VLTVCFGATDTALL 571
           V  +C   TDTA++
Sbjct: 184 VNCICPSFTDTAMV 197


>UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=16; Bacillaceae|Rep:
           Oxidoreductase, short-chain dehydrogenase/reductase
           family - Bacillus anthracis
          Length = 264

 Score = 93.1 bits (221), Expect = 5e-18
 Identities = 69/217 (31%), Positives = 110/217 (50%), Gaps = 7/217 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           ++KV+ ITGA++GIGE V   + ++G   + ++   EE  K+L  ++   Y     +Y  
Sbjct: 6   QNKVIVITGASSGIGEQVAMQVAEQGATPV-LMARTEEKLKALADKIKETYNTPCYYYVL 64

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITST 343
           DV+ E     + + V+QE G ID+++NNA         + S+   K   +VNV  L+  T
Sbjct: 65  DVSEETEVQSVFSKVLQEVGRIDILVNNAGFGIFKTFEDASMDEVKDMFQVNVFGLVACT 124

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              +  M K + G    +IN++S+A    +     Y ATK AVL F+N + R E  S T 
Sbjct: 125 KAVLPYMVKRNEGH---IINIASLAGKIATPKSSAYAATKHAVLGFTNSL-RME-LSSTN 179

Query: 524 VRVLTVCFGATDTALL-TDEKLGTFDKYLEFFMLGPT 631
           V V  +  G  DT      ++ GT+ K +  +ML PT
Sbjct: 180 VFVTAINPGPIDTNFFEIADQSGTYVKNMGRYMLKPT 216


>UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma
           infestans|Rep: Oxidoreductase - Triatoma infestans
           (Assassin bug)
          Length = 252

 Score = 93.1 bits (221), Expect = 5e-18
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KD+V  +TGA+ GIGE++ R L + G+K +A L    +  + LQ + N+  G+  K Y+ 
Sbjct: 5   KDRVAVVTGASAGIGEAIARALAEHGMK-VAALARRLDRLQKLQDDCNNFIGS-IKPYKC 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 343
           DVTNE      + ++V + G I V++NNA L     M D S G  ++  E NV  L+T T
Sbjct: 63  DVTNETEIATTIKSIVSDLGPISVLVNNAGLYENVPMTDTSQGSCRQTYETNVIGLVTFT 122

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVA--ALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517
              +EIM KH+    G +IN++S+A   +     M  Y A+K AV   +  +       K
Sbjct: 123 QHVVEIMKKHN-ITDGHIININSLAGHVIIPKPGMANYTASKHAVTVLTESLKNELAAMK 181

Query: 518 TGVRVLTVCFGATDT 562
           + +RV ++  G  +T
Sbjct: 182 SKIRVTSISPGLVNT 196


>UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Methanospirillum hungatei JF-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Methanospirillum hungatei
           (strain JF-1 / DSM 864)
          Length = 249

 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 62/214 (28%), Positives = 107/214 (50%), Gaps = 6/214 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           ++KV+ +TG + GIG+++     DEG K +   +  EE+ K++  E++ K G+     ++
Sbjct: 6   ENKVLLVTGGSRGIGKAIALRCADEGAKVVITWESHEESAKNVVNEIHHKNGSAMAI-QA 64

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITST 343
           DV NE+    ++N +  E G +D+++NNA +M +++ +  K  E       N       +
Sbjct: 65  DVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYS 124

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             A ++M KH   K G +IN+SSV  +  S    +Y ATKS ++ F+  + +       G
Sbjct: 125 RAAAKLMLKH---KSGRIINISSVVGVYGSKGQSVYSATKSFLIAFTKSLAK--ELGPFG 179

Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLEFFMLG 625
           + V  +  G  DT L  D K  T    L    LG
Sbjct: 180 ITVNAIAPGFIDTDLTHDVKDETRQDLLSHIPLG 213


>UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=7; Alphaproteobacteria|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 261

 Score = 92.3 bits (219), Expect = 9e-18
 Identities = 55/162 (33%), Positives = 89/162 (54%), Gaps = 7/162 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YRSD 184
           K  FITG A G+G +  R+L  EG K +A+ DI     +++  E+N+ +G  T F +  D
Sbjct: 11  KKAFITGGAQGLGAAAGRMLAKEGAK-VALADINLAGAQAVADEINAAHGAGTAFAFELD 69

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTL 346
           VT E+ ++ +L       GG+ V++NNA +  D        G++KK + VNV ++     
Sbjct: 70  VTQEDQWIDVLEKATAAMGGLSVLVNNAGIGGDGPIESLDFGLWKKVMSVNVDSVFLGAK 129

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 472
            A+  M  H   + G++IN+SS+A L  +   P Y A+K+AV
Sbjct: 130 HALTHMRAH---QPGSIINLSSIAGLIANGNSPAYNASKAAV 168


>UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1;
           Planctomyces maris DSM 8797|Rep: Probable putative
           oxidoreductase - Planctomyces maris DSM 8797
          Length = 270

 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 61/195 (31%), Positives = 94/195 (48%), Gaps = 3/195 (1%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +D+VV +TG + GIGE   R+   EG  H+AIL     AG+ L  ELN     K  F + 
Sbjct: 19  QDRVVIVTGGSKGIGEGCSRVFCAEG-GHVAILARGLHAGQDLARELNETGPGKAMFVQC 77

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKA 352
           DV   E     ++ VV++ G +D +INNA +   ++ + + +IE     +     ST   
Sbjct: 78  DVGEHEQIRSAIDLVVEQFGRLDCIINNAGVHPPAMSLEETSIEEMEQLMRVNFLSTFAG 137

Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
            +    H     GT+IN+SS+ A+   H    Y +TK A + F+  +       + GVRV
Sbjct: 138 AKYALPHLRKTKGTIINMSSMTAVLGQHHSTAYCSTKGAQVSFTKSLA--IELGEAGVRV 195

Query: 533 LTVCFGATDTALLTD 577
             +     DT L+ D
Sbjct: 196 NAILPSNIDTPLMRD 210


>UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family
           protein; n=4; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase family protein - Gramella
           forsetii (strain KT0803)
          Length = 249

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 66/204 (32%), Positives = 104/204 (50%), Gaps = 9/204 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K K + ITGA++GIGE+    L  EGV ++ +    EE  K L+ +++ + G K      
Sbjct: 4   KGKTIIITGASSGIGEATAMRLAKEGV-NVVLTARREEKLKELKSKIDKENGGKALVIPG 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 343
           DVT +E F  +++   +E G ID +INNA LM      N     + K ++VN+  ++   
Sbjct: 63  DVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLNGV 122

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              +  M +    K G +IN+SS AA        +Y ATKSAV  FS  + R E   K  
Sbjct: 123 AAVLPTMMEQ---KSGNIINISSSAARKIYPGGAVYCATKSAVKMFSEGL-RQELAPKFN 178

Query: 524 VRVLTVCFGATDTAL---LTDEKL 586
           + + ++  G  DT L   +TD+++
Sbjct: 179 INITSIEPGFVDTELTDTITDDEI 202


>UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep:
           Oxidoreductase - Oceanobacillus iheyensis
          Length = 244

 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 59/198 (29%), Positives = 100/198 (50%), Gaps = 6/198 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +DKV  ITG  +GIG +  ++   EG K I ++D+ EE G S++ EL S+ G++  F ++
Sbjct: 4   QDKVAVITGGVSGIGAATAKLFASEGAKLI-LVDMNEEKGASIEAELKSQ-GSEAIFIKA 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 343
           DVTNEE    I    +   G +D++ NNA +         +   ++K +EV++  +    
Sbjct: 62  DVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVA 121

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             AI+   K      G ++N +S+     S     Y A K+ V+  +  +G    ++   
Sbjct: 122 QAAIKEFLK---AGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGL--EYAARN 176

Query: 524 VRVLTVCFGATDTALLTD 577
           +RV  +C G  DTA+L D
Sbjct: 177 IRVNALCPGFIDTAILGD 194


>UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000025423 - Anopheles gambiae
           str. PEST
          Length = 191

 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 54/184 (29%), Positives = 94/184 (51%), Gaps = 1/184 (0%)
 Frame = +2

Query: 20  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTNEE 199
           + G   G+G ++ + LL +GVK + I+D+ E    +L     S           D++N  
Sbjct: 10  VFGGCGGMGMAIGQHLLRQGVKKLCIVDVVELTDSNLSCLKESGRDALILCKICDISNRA 69

Query: 200 HFLGILNAVVQEQ-GGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHS 376
               +L   + E  G ID+++N+A ++   +    K I    T +I S L A+ +M +  
Sbjct: 70  ALKQLLERDISEALGSIDILVNSAGIVESEVP--DKLIG---TGVINSCLIALNLMSRAK 124

Query: 377 GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCFGAT 556
           GGKGG ++NV+S A L     +P Y A+K  ++ F+  +G    +S+TGV+ + +C G T
Sbjct: 125 GGKGGVIVNVASTAGLEPIPFLPTYCASKHGLIGFTRSLGVEPVYSETGVKFIIICPGGT 184

Query: 557 DTAL 568
            T +
Sbjct: 185 RTRM 188


>UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritima
           TM0297 Oxidoreductase; n=7; Ascomycota|Rep: Similar to
           tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 291

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 60/195 (30%), Positives = 102/195 (52%), Gaps = 8/195 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG A G+G S+   L   G+K IAILD+ ++ G     +L+  YG + +FY++DV
Sbjct: 46  KVAIVTGGARGLGFSMAEGLCSVGLKGIAILDVQQDLGLDAIEKLHKAYGVQAQFYKADV 105

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349
            +EE    I++ VV + G +DVV+N+A + +           +++ I++N+      T  
Sbjct: 106 RDEESVNEIIDRVVHDLGSVDVVVNSAGVADLVHAAEYPADKFRRVIDINLNGSFLVTQA 165

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCVGRPEHFSKTG 523
           A   M K   G GGTV+ ++S++    +   P   Y A+K+AV   S  +     ++   
Sbjct: 166 AARHMIKQ--GTGGTVVFIASMSGSIVNWPQPQSAYNASKAAVKHLSKSLA--AEWAVHN 221

Query: 524 VRVLTVCFGATDTAL 568
           +R  ++  G  DTAL
Sbjct: 222 IRCNSISPGYMDTAL 236


>UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Flavobacterium johnsoniae UW101|Rep: Short-chain
           dehydrogenase/reductase SDR - Flavobacterium johnsoniae
           UW101
          Length = 269

 Score = 87.4 bits (207), Expect = 3e-16
 Identities = 61/190 (32%), Positives = 100/190 (52%), Gaps = 6/190 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY-GNKTKFYR 178
           KDK + ITG  TGIG+++  +L+  G + + I    E+  K+   ++  ++ G++     
Sbjct: 30  KDKKIVITGGTTGIGKAIADVLVSLGGR-VLIFGRDEKDFKNAVADIQKQFPGSEVYGTP 88

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIGIYKKAIEVNVTALITST 343
           +DVT +E    IL     E GGID++INNAAL      N+S   YK  I+ N+T  +   
Sbjct: 89  ADVTKKEDIQKILEIADNELGGIDILINNAALGAPGITNESYDDYKYIIDTNITGYLAFA 148

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
            +A   M +    K G +IN+ S++A ++     IY ATKSA+  FS  + +    +  G
Sbjct: 149 QEAASRMKQQ---KSGHIINIGSMSAESKEAKSTIYVATKSAIRGFSTSLRK--ELNPLG 203

Query: 524 VRVLTVCFGA 553
           ++V  +  GA
Sbjct: 204 IKVSLIEPGA 213


>UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus
           sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp.
           B14905
          Length = 252

 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 56/195 (28%), Positives = 96/195 (49%), Gaps = 7/195 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +K+  +TGA +GIG +    L   G K + I+D  +E G+   ++L  + G +  F ++D
Sbjct: 5   NKIAVVTGAGSGIGRASSLKLASNGAK-VVIVDFNKETGEET-LKLVKEQGGEGIFVQAD 62

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITST 343
           V+  E     +NA V+  G IDV  NNA ++     +       Y + + +NV  +    
Sbjct: 63  VSKSEDVEKYVNAAVETYGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGVFLGL 122

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              I++M    G   G++IN +S A +   H M +Y A+K AV+  +        + K G
Sbjct: 123 KHVIKVM---EGQGSGSIINTASTAGVRSEHSMAVYSASKHAVIGLTKSASL--EYVKKG 177

Query: 524 VRVLTVCFGATDTAL 568
           +R+  +C G  +TAL
Sbjct: 178 IRINAICPGGVETAL 192


>UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=2; Actinomycetales|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Mycobacterium avium (strain 104)
          Length = 250

 Score = 86.6 bits (205), Expect = 4e-16
 Identities = 56/189 (29%), Positives = 101/189 (53%), Gaps = 4/189 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGAA+GIGE+  + L ++G K + + DI E+ G+ +  E+ ++ G +  F R+D+
Sbjct: 6   KVAVVTGAASGIGEATAKRLAEDGAK-VVVADINEDGGERVVAEI-AERGGEAAFLRTDI 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTAL-ITSTLKAIE 358
           + EE    +++  V   GG+ +  NNAA+ +    +++ + +V   VT + +  T   + 
Sbjct: 64  SIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLHELSTDVFDTVTGIGLRGTFFCMR 123

Query: 359 IMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
               H  G  GG ++N +S AAL  +  M  Y ATK  ++  +   G    +++ G+RV 
Sbjct: 124 AEIAHMIGHGGGAIVNTASGAALKAAAGMHAYVATKHGIVGLTRNAGL--DYARNGIRVN 181

Query: 536 TVCFGATDT 562
            V  G+  T
Sbjct: 182 AVAPGSIKT 190


>UniRef50_Q2W431 Cluster: Dehydrogenase with different
           specificities; n=2; Magnetospirillum|Rep: Dehydrogenase
           with different specificities - Magnetospirillum
           magneticum (strain AMB-1 / ATCC 700264)
          Length = 248

 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 65/212 (30%), Positives = 104/212 (49%), Gaps = 6/212 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +DKV  ITG A+GIG   V+ + + G   + I DI  EAG+    EL +K G K +F R 
Sbjct: 4   EDKVALITGGASGIGYCTVKSMAELGA-DVLIADINVEAGEKAAAELTAK-GFKAEFVRL 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 343
           DVT++ +   +   VV  +G +D++ N A        +++      K + +N+T  I   
Sbjct: 62  DVTDKANIARVKEHVVATRGRLDILCNVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIELI 121

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
                +M +   GK   ++NV+S A    S    +Y A K  ++ FS  + R    ++  
Sbjct: 122 RAFFPLMIEKKTGK---IVNVASDAGRVGSLGESVYSAAKGGLIAFSKALAR--EGARFN 176

Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLEFFM 619
           + V  +C G TDT LL  E     +K+LE F+
Sbjct: 177 INVNAICPGPTDTPLLKSEP----EKFLEAFL 204


>UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Herpetosiphon aurantiacus ATCC
           23779|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Herpetosiphon aurantiacus ATCC 23779
          Length = 247

 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 57/195 (29%), Positives = 103/195 (52%), Gaps = 7/195 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG A GIG +  ++L  +G   + I DI E+ G +   ++    G +  F   DV
Sbjct: 5   KVAIVTGGAIGIGAATAQLLAKQGAI-VVIGDINEQTGLATVEQIRGNAG-QAYFRHCDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITSTL 346
           ++E     ++   + +QGG+D++INNA +      ++       ++ +++++T +     
Sbjct: 63  SHEADIQALVQFAL-DQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQK 121

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
            A + M   +GGKGG ++NV+S+A +  S  +  Y   K+ V+Q S   G  E  +  G+
Sbjct: 122 YASQAM--LAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSK-TGAIE-LASAGI 177

Query: 527 RVLTVCFGATDTALL 571
           R+  VC G T+TA+L
Sbjct: 178 RINAVCPGWTETAIL 192


>UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein
           reductase - Leptospira interrogans
          Length = 254

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 60/203 (29%), Positives = 100/203 (49%), Gaps = 6/203 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K K   +TGAA GIG+S    L   G  ++ I D+ EE+ K+   E++ + G K     +
Sbjct: 5   KGKNAVVTGAARGIGKSTALTLAKAGA-NLVIADLNEESSKATADEISKQTGVKAIGIGT 63

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITST 343
           +V++ +     + A V E G +D+++NNA +  D++ +  K       I VN+T     T
Sbjct: 64  NVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCT 123

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             AI+ M K+    GG++IN+SS+A +  +     Y A+K+ V+ F+  V       K  
Sbjct: 124 QAAIKFMMKNP--NGGSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVR 181

Query: 524 VRVLTVCFGATDTALLTDEKLGT 592
              +   F AT+      EK+ T
Sbjct: 182 CNAIAPGFIATEMTDAIPEKIRT 204


>UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:
           Dehydrogenase - Bradyrhizobium japonicum
          Length = 271

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 56/194 (28%), Positives = 101/194 (52%), Gaps = 7/194 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG A+GIGE++V +   EG   IA  D+ E  G  L   + +K G K  F   DV
Sbjct: 10  KVALVTGGASGIGEAIVELFAREGATVIA-TDVDELRGPELAKRI-TKAGGKAIFLEQDV 67

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVNVTALITSTL 346
           ++EE ++ I+  + +  G +D++++NA       ++++ ++G ++K   +N+  +  S  
Sbjct: 68  SSEERWIEIVAEIAKRYGRLDIMVSNAGIGIAVPSIVDMTLGDWRKQNAINLDGVFLSVK 127

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             + +M K     GG+++ +SS+A L  +  +  Y ATK  V  F+  +         G+
Sbjct: 128 HCLPLMRKTG---GGSIVMMSSLAGLRGAPGLSAYSATKGGVRLFAKSIAMECAAVGDGI 184

Query: 527 RVLTVCFGATDTAL 568
           RV +V  G  DT +
Sbjct: 185 RVNSVHPGIIDTPI 198


>UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=3; cellular organisms|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus
           furiosus
          Length = 260

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 58/201 (28%), Positives = 102/201 (50%), Gaps = 6/201 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K+KV  +TG   GIG ++ ++  + G K + + +I EEAG   +  L  + G    F ++
Sbjct: 7   KNKVAIVTGGGQGIGAAIAQLFAENGAK-VVLAEIDEEAGLEREAMLRER-GLDVTFIKT 64

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITST 343
           DV +EE    ++   V+  GG+D+++NNAA+M+       ++  +++ I VN+T     +
Sbjct: 65  DVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYICS 124

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             A E M K     GG +IN++S  AL        Y A+K  +L  ++ +      +K  
Sbjct: 125 RYAAEEMIKRG---GGVIINIASTRALMSEPDTEPYSASKGGLLALTHSLA--ISLAKYR 179

Query: 524 VRVLTVCFGATDTALLTDEKL 586
           +RV+ V  G  +T+     KL
Sbjct: 180 IRVVAVSPGWIETSRWKKSKL 200


>UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Sphingomonadales|Rep: Short-chain
           dehydrogenase/reductase SDR - Sphingopyxis alaskensis
           (Sphingomonas alaskensis)
          Length = 285

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 4/189 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGAA+GIG++ V  L  EG  H+   DI E  G++L    N +      F R DV
Sbjct: 6   KVAVVTGAASGIGKATVLKLAGEGA-HVFAADIDEAGGRALADASNGRID----FVRCDV 60

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK---KAIEVNVTALITSTLKAIE 358
           T       +++A   + GGID+V NNAA   D   I +   +  +  +  ++ S    I 
Sbjct: 61  TVPSDIEALMDAAAAKAGGIDIVFNNAAAGGDRAPIDEITPEGWDATMDLVLKSVAMGIR 120

Query: 359 IMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
               H  G KG +++N +SVAAL   +    Y   K+ VL  +         ++ G+RV 
Sbjct: 121 YAAPHMKGRKGASIVNTASVAALGAGYSPTAYAVAKAGVLHLTRVAA--TDLAQYGIRVN 178

Query: 536 TVCFGATDT 562
            +C G  +T
Sbjct: 179 AICPGFINT 187


>UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 251

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 61/203 (30%), Positives = 98/203 (48%), Gaps = 6/203 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITG A G GE+  R  + EG + + I D+ +EAG+ +  EL    G+  +F   DV
Sbjct: 7   KVALITGGARGQGEAEARRFVAEGAR-VVIADVLDEAGQRVAAEL----GDAARFQHLDV 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349
           T E  +   ++A + + G +D+++NNAA++        S+  Y+K I+VN          
Sbjct: 62  TREADWQIAVDATLAQFGRLDILVNNAAILKLVPIEACSLDDYRKVIDVNQVGCWLGMKS 121

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A   +G      GG+++NVSS A +        Y ++K AV   +        F + G+R
Sbjct: 122 A---LGALKAAGGGSIVNVSSTAGMEGVAGGSAYVSSKFAVRGMTKAAAL--EFGRYGIR 176

Query: 530 VLTVCFGATDTALLTDEKLGTFD 598
           V +V  G  DT +    +   FD
Sbjct: 177 VNSVHPGGIDTVMARPPEFADFD 199


>UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa
           protein; n=44; Drosophiliti|Rep: Alcohol
           dehydrogenase-related 31 kDa protein - Drosophila
           melanogaster (Fruit fly)
          Length = 272

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 56/194 (28%), Positives = 95/194 (48%), Gaps = 1/194 (0%)
 Frame = +2

Query: 38  GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN-EEHFLGI 214
           GI     ++L+ + +  +AIL   E      Q++ + K   +  F+  DVT   E     
Sbjct: 17  GIALETSKVLMTKNIAKLAILQSTENPQAIAQLQ-SIKPSTQIFFWTYDVTMAREDMKKY 75

Query: 215 LNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGT 394
            + V+ +   IDV+IN A L +++       I  N+T ++ +    +  M +  GG GG 
Sbjct: 76  FDEVMVQMDYIDVLINGATLCDENN--IDATINTNLTGMMNTVATVLPYMDRKMGGTGGL 133

Query: 395 VINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCFGATDTALLT 574
           ++NV+SV  L  S V   Y A+K  V+ F+  +  P ++S+ GV V+ VC G   T +  
Sbjct: 134 IVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCG--PTRVFV 191

Query: 575 DEKLGTFDKYLEFF 616
           D +L  F +Y + F
Sbjct: 192 DRELKAFLEYGQSF 205


>UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase
           bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis
           oxidoreductase bacC - Bacillus subtilis
          Length = 253

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 60/194 (30%), Positives = 101/194 (52%), Gaps = 6/194 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           DK V ITG A+GIG + V+  L +   ++ + DI E  G+++  + N+   ++  F ++D
Sbjct: 5   DKTVLITGGASGIGYAAVQAFLGQQA-NVVVADIDEAQGEAMVRKENN---DRLHFVQTD 60

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 346
           +T+E      + + V   GG+DV+INNA       +    +  + K ++VN+T +   + 
Sbjct: 61  ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 120

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
            A++ M   + GK G +IN  SV  L     +P Y A+K  VLQ +  +     ++K  +
Sbjct: 121 HALKHM--LAAGK-GNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMA--VDYAKHQI 175

Query: 527 RVLTVCFGATDTAL 568
           RV  VC G  DT L
Sbjct: 176 RVNCVCPGIIDTPL 189


>UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces
           avermitilis|Rep: Putative dehydrogenase - Streptomyces
           avermitilis
          Length = 258

 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 60/199 (30%), Positives = 104/199 (52%), Gaps = 6/199 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +VV I+GAA G GE   R+ ++EG K + + D+ ++ G++L  E+ ++Y         DV
Sbjct: 7   RVVLISGAARGQGEQEARLFVEEGAK-VVVADVLDDQGEALAKEIGARY------VHLDV 59

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 349
             E+ +   +       G ID ++NNA ++  ND +G     +++ ++VN   +    +K
Sbjct: 60  GREDDWQAAVTVAKDAYGHIDGLVNNAGILRFNDLVGTPLAEFQQIVQVNQVGVFLG-IK 118

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            +    + +G  GGT++N +S A LT    +  Y ATK A++  +  V   E  +K  +R
Sbjct: 119 TVAPEIEAAG--GGTIVNTASYAGLTGMAYVGAYTATKHAIVGLTR-VAALELAAKK-IR 174

Query: 530 VLTVCFGATDTALLTDEKL 586
           V  VC GA DTA+    +L
Sbjct: 175 VNAVCPGAIDTAMSNPSQL 193


>UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
          Length = 260

 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 59/206 (28%), Positives = 101/206 (49%), Gaps = 7/206 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +K + ITG A+GIG +  ++L   G K I I D+AE+ G +L  +  +   +   F + D
Sbjct: 14  NKRILITGGASGIGAASAKLLASRGAK-IIIADLAEDLGHALAQQAWAS-DHTINFMKVD 71

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITST 343
           VT       +    V++ GG+DVVINNA + +    +++       + + VNV  +    
Sbjct: 72  VTQAAEVNALFAYAVEQLGGLDVVINNAGVDHPPAPLHQLTEDDFDRCMTVNVKGVWHCM 131

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             AI  +  H GG    VINV+S+A L  + ++  Y A+K AV+  +        +++  
Sbjct: 132 RAAIACLSPHGGGH---VINVASIAGLRSAPMLSAYSASKHAVIGLTKSAA--IEYARAN 186

Query: 524 VRVLTVCFGATDTALLTDEKLGTFDK 601
           +R   VC    DT ++ +  L   +K
Sbjct: 187 IRFNAVCPSFIDTPMVRNSMLNMNEK 212


>UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485;
           Drosophilidae|Rep: Alcohol dehydrogenase - Drosophila
           melanogaster (Fruit fly)
          Length = 256

 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 57/189 (30%), Positives = 93/189 (49%), Gaps = 2/189 (1%)
 Frame = +2

Query: 11  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVE-LNSKYGNKTKFYRSDV 187
           V+F+ G   GIG    + LL   +K++ ILD  E      +++ +N K      FY  DV
Sbjct: 10  VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKV--TVTFYPYDV 66

Query: 188 TNE-EHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364
           T        +L  +  +   +DV+IN A +++D     ++ I VN T L+ +T   ++  
Sbjct: 67  TVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQ--IERTIAVNYTGLVNTTTAILDFW 124

Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544
            K  GG GG + N+ SV      + +P+Y  TK+AV+ F++ + +      TGV   TV 
Sbjct: 125 DKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYTVN 182

Query: 545 FGATDTALL 571
            G T T L+
Sbjct: 183 PGITRTTLV 191


>UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=1; Bacillus halodurans|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus
           halodurans
          Length = 247

 Score = 82.6 bits (195), Expect = 7e-15
 Identities = 57/222 (25%), Positives = 106/222 (47%), Gaps = 10/222 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +DKV  +TGA  GIG+ +V+  +++G     I     EA + ++  LN   G K   Y S
Sbjct: 4   RDKVAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQ--GEKCVSYVS 61

Query: 182 DVTNEEHFL-GILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 340
              +++ F+  +  +VV +   +D+++NNA +  D          +++ ++VN     T 
Sbjct: 62  GSVDDQLFIHSLFKSVVDKHNRLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYTC 121

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
              A+  M +   GK   ++NV SV  +        Y A+K A++  +  + R   +S+ 
Sbjct: 122 CHAALPYMERKKQGK---IVNVVSVTGVVGREAQTNYGASKGAIIGLTRLLAR--KYSEK 176

Query: 521 GVRVLTVCFGATDTALL---TDEKLGTFDKYLEFFMLGPTKE 637
           G+ +  +  G  +T ++    +EKL  F ++     LG TKE
Sbjct: 177 GISINAIAPGMIETEMIKQVPEEKLKNFLRFTNAKKLGSTKE 218


>UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier
           protein) reductase - Leptospira interrogans
          Length = 256

 Score = 82.6 bits (195), Expect = 7e-15
 Identities = 60/199 (30%), Positives = 100/199 (50%), Gaps = 7/199 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDKV  +TG +TGIG++VV+  + +GVK +       E GK L+ E+ ++ G    F   
Sbjct: 6   KDKVAIVTGGSTGIGKAVVKEFVSKGVK-VVFCGRRLEEGKKLESEIRAE-GGDVYFVVC 63

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM--NDSI-----GIYKKAIEVNVTALITS 340
           DVT+ E    +++A +++ G +D  INNA +M  N  +      ++ K + VN+     S
Sbjct: 64  DVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLKGTWLS 123

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               I  M K     GG V+NVSS++ +     +  Y A K  V+  +        ++K 
Sbjct: 124 MKYQIPEMIKMG---GGVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAAL--EYAKK 178

Query: 521 GVRVLTVCFGATDTALLTD 577
            +R+  +C GA  T +L +
Sbjct: 179 NIRINAICPGAVKTEILDE 197


>UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3;
           Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp.
           SG-1
          Length = 279

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 54/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           ++K   ITGA +G+G+S    L  EG+  IA++DI EE G    VE+  + G    F ++
Sbjct: 31  ENKAAIITGAGSGLGQSAAVRLAKEGI-DIAVVDINEEGGNE-TVEMVKQKGVNAIFIKA 88

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITS 340
           DV+  E     ++  V+E G +D   NNA +       +N  I   ++ + +N+   +  
Sbjct: 89  DVSKAEEVKNYVDKTVEEFGKVDYFFNNAGISGSGQYFLNTEIEEIEQVVSINLMGALYG 148

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
                E+M K+    GG+++N +S A +     +  Y ATK  ++  +  +     ++K 
Sbjct: 149 VRYVAEVMMKNG---GGSIVNTASSAGVIGQDSVVTYSATKHGIIGLTKSM--VAEYAKE 203

Query: 521 GVRVLTVCFGATDTALL 571
           G+RV  +  G T+T ++
Sbjct: 204 GLRVNAIAPGPTETPMV 220


>UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=1;
           Apis mellifera|Rep: Short-chain dehydrogenase/reductase
           - Apis mellifera (Honeybee)
          Length = 246

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 52/188 (27%), Positives = 100/188 (53%), Gaps = 9/188 (4%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           D+V  +TGA +GIG+ ++  L+ +G+K I I    ++  K+L  EL SK G K    + D
Sbjct: 7   DEVALVTGANSGIGKCLIECLVGKGMKVIGIAPQVDKM-KTLVEELKSKPG-KLVPLQCD 64

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTL 346
           ++N+   L ++  V +  G ID++INNA       L ND +  +KK  ++N+  L     
Sbjct: 65  LSNQNDILKVIEWVEKNLGAIDILINNATINIDVTLQNDEVLDWKKIFDINLLGLTCMIQ 124

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALT---QSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517
           + +++M K  G   G ++N++  + L     +   P Y A+K A+   ++C+       +
Sbjct: 125 EVLKLM-KKKGINNGIIVNINDASGLNLLPMNRNRPAYLASKCALTTLTDCLRSELAQCE 183

Query: 518 TGVRVLTV 541
           + ++V+++
Sbjct: 184 SNIKVISI 191


>UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9;
           Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas
           sp. (strain NCIMB 9872)
          Length = 250

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 53/166 (31%), Positives = 84/166 (50%), Gaps = 6/166 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           DKVV +TG A G+G +   +L  EG   + + D+ EE G     E+  + G K  F   D
Sbjct: 6   DKVVLVTGGAMGMGLTHCTLLAREGAT-VYLSDMNEELGHQAVAEIR-RQGGKAHFLHLD 63

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 346
           VTNE H+ G ++ ++ E   +D ++NNA ++      + S   + +  E+NV ++   T 
Sbjct: 64  VTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTR 123

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 484
             IE M K      G ++NVSS+  L  +     Y A+K AV  F+
Sbjct: 124 AVIEPMRK---AHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFT 166


>UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Rep:
           Blr4846 protein - Bradyrhizobium japonicum
          Length = 255

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 54/170 (31%), Positives = 87/170 (51%), Gaps = 5/170 (2%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           D+VV ITG A+GIG + VR    +G + +A LDI E AG SL  E+ +  G    F R D
Sbjct: 11  DRVVLITGGASGIGAAFVRAFAAQGAR-VAFLDIDEAAGGSLVEEVAAASGAAPLFVRCD 69

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI--- 355
           + + +     +  V    G   V++NNAA  ND   +  +        +I   LK +   
Sbjct: 70  LLDIDALRAAIAQVRGSLGDAAVLVNNAA--NDQRQVLAEVTPSEFDWMIGVNLKHVFFA 127

Query: 356 --EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499
              ++ +     GG++IN+SS+A +     +P+Y A K+A++ F+N + R
Sbjct: 128 AQAVVPQMQARGGGSIINMSSIAWMRGGPALPVYAAAKAAIVGFTNSLAR 177


>UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 262

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 53/191 (27%), Positives = 93/191 (48%), Gaps = 2/191 (1%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           ++KV  ITGAA+GIG +  R+L  EG  H+ + D+ +  GKS+  +L    G      + 
Sbjct: 7   ENKVAVITGAASGIGAATARLLAREGA-HVVLADVNDNGGKSIAADL----GPTAMAVKC 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKAI 355
           DV++      ++ A V+  G ID++ NNA +     S+ I     E  +   + S   A 
Sbjct: 62  DVSSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYAC 121

Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
                H   +G  ++N +S++ L   +    Y A K AV+ ++  +   +H  + G+RV 
Sbjct: 122 HFAIPHM-PRGSAIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALA-VDH-GRDGIRVN 178

Query: 536 TVCFGATDTAL 568
            +C G  +T +
Sbjct: 179 ALCPGLVETPI 189


>UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Leeuwenhoekiella blandensis MED217
          Length = 257

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 52/180 (28%), Positives = 92/180 (51%), Gaps = 6/180 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K+KV  +TG A+G+G+S  ++L  EG K I + DI EE GK + V+   + G +  F + 
Sbjct: 5   KNKVAIVTGGASGLGKSSAKLLAREGAK-IVVSDIDEEGGKKV-VQQIKEDGGEAIFIKQ 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 343
           DV  E+ +  ++   ++  G + ++ N+A +     + D ++  +K  I++N+      T
Sbjct: 63  DVAKEDEWKNVIETTLETYGKLHILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGT 122

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              I+  G     +GG++IN SS+  L     +P Y A+K  V  F+       H +K G
Sbjct: 123 KYGIK--GMRKTDEGGSIINFSSIEGLIGDPNLPAYNASKGGVTIFTKSAAL--HCAKQG 178


>UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 277

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 55/193 (28%), Positives = 100/193 (51%), Gaps = 6/193 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K+  +TGAA G+G ++ +  L+EG   + + D++EE       EL +    +    R DV
Sbjct: 9   KIAIVTGAARGLGAAIAKRYLEEGAT-VVLADLSEEKTTERAAELGAGAHGR----RCDV 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349
            + E F  +++A V E G +D+++NNA +         S+  +   + VNV+++      
Sbjct: 64  GDWEAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRA 123

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           AI  M +  GG    +INV+S+A L    +   Y A+K+AV+ F+  +   +H +   +R
Sbjct: 124 AIPHMRRQGGG---AIINVASIAGLRGETLAAAYSASKAAVVNFTRSLAL-DH-ADENIR 178

Query: 530 VLTVCFGATDTAL 568
           V  +C G+ +T +
Sbjct: 179 VNAICPGSVETEM 191


>UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;
           n=2; Thermotoga|Rep: Uncharacterized oxidoreductase
           TM_0325 - Thermotoga maritima
          Length = 251

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 62/191 (32%), Positives = 93/191 (48%), Gaps = 6/191 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KVV ITGA +GIG+    +  + G K +AI DI+EE GK   VEL    G +  F   DV
Sbjct: 6   KVVLITGAGSGIGKKAAVMFAERGAK-VAINDISEEKGKE-TVELIKSMGGEAAFIFGDV 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 349
             +     I+   V+  G +D+++NNA ++        S   + K + VNV      +  
Sbjct: 64  AKDAE--QIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLLSKY 121

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A+E M K     GG ++NVSS A L       +Y  +K+A+L  +  +     +   G+R
Sbjct: 122 AVEQMKKQG---GGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLA--VDYVDYGIR 176

Query: 530 VLTVCFGATDT 562
           V  VC G T +
Sbjct: 177 VNAVCPGTTQS 187


>UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep:
           All3753 protein - Anabaena sp. (strain PCC 7120)
          Length = 263

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 60/192 (31%), Positives = 94/192 (48%), Gaps = 6/192 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +   ITGAA+GIG  +V I  +    ++ ++D A+E  + + +E   K+G   K    D+
Sbjct: 7   QTALITGAASGIGYELVCIFAENDY-NLVLVDRAKEKLEEIAIEFQDKFGISVKPIVRDL 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDS-IGIYKKAIEVNVTALITSTLK 349
           +       I   V Q    +DV++NNA      L ND+ +    + ++VNV      T  
Sbjct: 66  SKTTSPEEIFQEVEQANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTTHLTKL 125

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            ++ M +   GK   ++NVSS AA     +M +YFATK+ VL FS  +        TGV 
Sbjct: 126 FLKNMVQQGEGK---ILNVSSAAAFQPGPLMAVYFATKAYVLSFSEALA--NELDGTGVT 180

Query: 530 VLTVCFGATDTA 565
           V  +C G T +A
Sbjct: 181 VTVLCPGTTQSA 192


>UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Bacteria|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Pseudomonas putida (strain KT2440)
          Length = 262

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 54/197 (27%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KVV +TGA +GIG +        G   +A+ DI+ + G    VEL    G +  F+  DV
Sbjct: 10  KVVLVTGAGSGIGRATALAFAQSGAS-VAVADISTDHGLKT-VELVKAEGGEATFFHVDV 67

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346
            +E     +L  VV   GG+D+  NNA +  + + +       +++ I+VN++++     
Sbjct: 68  GSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVNLSSVFYCLK 127

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             I +M K     GG ++N +S + L   + +  Y ATK  V+  +        ++   +
Sbjct: 128 GEIPLMLKRG---GGAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAA--IDYANQNI 182

Query: 527 RVLTVCFGATDTALLTD 577
           R+  VC G  D+  L D
Sbjct: 183 RINAVCPGPVDSPFLAD 199


>UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 258

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 54/190 (28%), Positives = 97/190 (51%), Gaps = 3/190 (1%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG A G+G +  R+ + EG   + I D+ +  G++L  EL    G+  +F R DV
Sbjct: 7   KVAIVTGGARGMGAATCRLFVAEGAC-VVIGDVLDAEGEALAREL----GDAARFMRLDV 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIEVNVTALITSTLKAIEI 361
            +E +++ + +A +++ G IDV++NNAA++       + K+  E  V+  +  T   I  
Sbjct: 62  ADEANWVRVTDATMEQFGRIDVLVNNAAVLTFGGITELSKRDFERAVSINLVGTFVGIRT 121

Query: 362 MGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
           +  H    K G+++N+SSV  L   + +  Y ++K  V   +            GVRV +
Sbjct: 122 IAPHMIAQKSGSIVNISSVDGLRGVNALAAYVSSKWGVRGLTKVAAL--ELGHQGVRVNS 179

Query: 539 VCFGATDTAL 568
           +  G  +TA+
Sbjct: 180 IHPGGVNTAM 189


>UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1;
           Psychroflexus torquis ATCC 700755|Rep: 3-oxoacyl-[ACP]
           reductase - Psychroflexus torquis ATCC 700755
          Length = 251

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 61/188 (32%), Positives = 101/188 (53%), Gaps = 2/188 (1%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K K   ITG + GIG+S+   L +EGV +IAI    +EA +  + EL  K G K      
Sbjct: 6   KGKNAIITGGSKGIGKSIALHLAEEGV-NIAICARGKEALQKTKNELLEK-GVKVFTQTC 63

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKAI 355
           DV + E F   L AV  E G +D+++NNA+   M D    ++ ++++++ A + +T K +
Sbjct: 64  DVGDSEQFNLFLTAVKNEFGSVDILVNNASALTMGDEYQDWEASLQIDLMASVRATKKVV 123

Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
             M + SG   G ++ +SSV+ L +S   P Y A K+A++ +S  +      +   +RV 
Sbjct: 124 PWMSE-SG--SGNILFISSVSGL-ESGSPPAYAAAKAALISYSKTMA--VQLAPQHIRVN 177

Query: 536 TVCFGATD 559
           T+  GA +
Sbjct: 178 TIAPGAIE 185


>UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier
           protein) reductase - Oceanobacillus iheyensis
          Length = 253

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 51/201 (25%), Positives = 102/201 (50%), Gaps = 7/201 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDKV  +TGAA+G+G+++  +   EG K + + D+ EE  +S+  E+ S  G  T   + 
Sbjct: 4   KDKVAIVTGAASGMGKAIATLYASEGAK-VIVADLNEEGAQSVVEEITSNNGVATAI-KV 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIG-----IYKKAIEVNVTALITS 340
           ++  +E    +++  V   G +D+++NNA +M+  +++G      +    ++N   ++ +
Sbjct: 62  NIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRA 121

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
             KAI I  +    + G ++N +S   L  +H    Y A+K AV+  +   G    ++ +
Sbjct: 122 MRKAIPIFLEK---ESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTG--YMYANS 176

Query: 521 GVRVLTVCFGATDTALLTDEK 583
           G+R   +  G   T + +  K
Sbjct: 177 GIRCNAIAPGGVATNITSSLK 197


>UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;
           n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase
           SSP0419 - Staphylococcus saprophyticus subsp.
           saprophyticus (strain ATCC 15305 /DSM 20229)
          Length = 234

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 58/207 (28%), Positives = 105/207 (50%), Gaps = 7/207 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKTKFYR 178
           +DKV  +TGA++GIG S+   L ++GVK +    D +  A  + +++ N +   +T    
Sbjct: 5   QDKVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSIV- 63

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 340
            DVT++E    ++    ++ G ID+++N+A LM  S      +  ++  I+VN+   + +
Sbjct: 64  -DVTHKEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTLYT 122

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               +  M   S G    +IN++S++    +    +Y A+K+AV   +   G  +  +KT
Sbjct: 123 INAVLPSMLNQSSGH---IINIASISGFEVTKKSTLYSASKAAVHSITQ--GLEKELAKT 177

Query: 521 GVRVLTVCFGATDTALLTDEKLGTFDK 601
           GVRV ++  G  DT L  D   G   K
Sbjct: 178 GVRVTSISPGMVDTPLSGDTDWGARKK 204


>UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus
           iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis
          Length = 257

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 61/197 (30%), Positives = 103/197 (52%), Gaps = 7/197 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +DKV+ +TGAA GIG+ VVR + +   K + ++D+ E+A KS+Q EL     N +   ++
Sbjct: 5   QDKVIIVTGAAGGIGKEVVRKVANAQAK-VVLVDLNEDAIKSVQAELGLTEEN-SFVVKA 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 340
           DV+NEE+    ++  + + G ID  +NNA +   +  I       +     +NV  ++  
Sbjct: 63  DVSNEENVKNYVDQTIAKFGRIDGFVNNAGVEGPAKSIEEITEKEFDFVYGINVKGVLFG 122

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               + +M      K G+++N +SVA L  S  M +Y ++K AV+   N V   E  +  
Sbjct: 123 LKYVLPVM---KAQKSGSIVNTASVAGLIGSPSMALYNSSKHAVMGL-NKVAALES-AAF 177

Query: 521 GVRVLTVCFGATDTALL 571
            VRV TV  G  +T ++
Sbjct: 178 NVRVNTVNPGVINTQMM 194


>UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Parvibaculum
           lavamentivorans DS-1
          Length = 268

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 9/197 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGAA GIG +  + L  EG K +   D   E G+ +  E+  + G  T F+R DV
Sbjct: 7   KVAIVTGAAKGIGAATAKALAREGAK-VVCSDFDAENGQVVADEIAGEGGTAT-FFRHDV 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 346
           T+E  +  ++    ++ GG+ VV+NNA +  +       ++  ++  IEV++ ++     
Sbjct: 65  TDEAQWEAVVKLAEEKFGGLHVVVNNAGIAPEAGPIEEKTLADWRHTIEVDLDSVFLGCK 124

Query: 347 KAIEIMGKHS--GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
             I  + K++  GG GG ++N+SS+  L        Y A K  V   +         +  
Sbjct: 125 HGIRTIKKYTSKGGAGGAIVNISSILGLVGQSGASDYNAAKGGVRLLTKSAALECADAGY 184

Query: 521 GVRVLTVCFGATDTALL 571
            +RV +V  G  DT ++
Sbjct: 185 NIRVNSVHPGYIDTPMV 201


>UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Bacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Methylobacterium
           sp. 4-46
          Length = 255

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 60/203 (29%), Positives = 96/203 (47%), Gaps = 6/203 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG A GIG +  R   +EG   + + DI  EAG +     N  +    +F   DV
Sbjct: 7   KVALVTGGARGIGLATARRFAEEGAAAVILADIDAEAG-ARAAATNPVF----RFAPLDV 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGI--YKKAIEVNVTALITSTLK 349
           T +  +    +  V  +GG+DVV+N A +      +S+ +  +++   VNV         
Sbjct: 62  TQDAAWQDATDEAVAREGGLDVVVNCAGIAVVATIESVTLEQWRRVQAVNVDGTFLGCRH 121

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A+ +M K   G+GG +IN+SSV+ +   H +  Y A+K AV   +  V         G+R
Sbjct: 122 AVRVM-KPPAGRGGAIINLSSVSGIIGGHNLAAYNASKGAVRLLTKSVALHCARQGYGIR 180

Query: 530 VLTVCFGATDTALLTDEKLGTFD 598
             ++  G T+T +L D   G  D
Sbjct: 181 CNSIHPGFTETDMLHDLAAGGRD 203


>UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family member
           11 precursor; n=30; Euteleostomi|Rep:
           Dehydrogenase/reductase SDR family member 11 precursor -
           Homo sapiens (Human)
          Length = 260

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 59/198 (29%), Positives = 98/198 (49%), Gaps = 11/198 (5%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSK-YGNKTKF 172
           +D++  +TGA+ GIG +V R L+ +G+K   ++  A   G  + L  E  S  Y      
Sbjct: 10  RDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLIP 66

Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALI 334
           YR D++NEE  L + +A+  +  G+D+ INNA       L++ S   +K    VNV AL 
Sbjct: 67  YRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALS 126

Query: 335 TSTLKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCVGRPEH 508
             T +A + M K      G +IN++S++   +    V   Y ATK AV   +  + +   
Sbjct: 127 ICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELR 185

Query: 509 FSKTGVRVLTVCFGATDT 562
            ++T +R   +  G  +T
Sbjct: 186 EAQTHIRATCISPGVVET 203


>UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2;
           Bacteria|Rep: Short-chain dehydrogenase -
           Symbiobacterium thermophilum
          Length = 254

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 60/194 (30%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITGAA G+G +   +   EG + + I D+ EE G++ Q       G    F R+DV
Sbjct: 7   KVAIITGAAMGMGAATAELFAREGAR-VVIADLNEELGRA-QARKIQDAGGAAAFVRADV 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367
           +       ++   V   G +DV +NNAA   D+  +     E    A+I   LK + +  
Sbjct: 65  SRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPL-ADLDEAVWDAVIGVDLKGVALCL 123

Query: 368 KHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           K+        G GG++IN+SSV+ +      P Y A K  V+  +        +S  G+R
Sbjct: 124 KYELRQMLKQGGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAAM--DYSPHGIR 181

Query: 530 VLTVCFGATDTALL 571
           V  V  GA DT +L
Sbjct: 182 VNAVAPGAVDTPML 195


>UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductase;
           n=3; Lactobacillales|Rep: 3-oxoacyl-acyl carrier protein
           reductase - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 249

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 57/200 (28%), Positives = 100/200 (50%), Gaps = 8/200 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK-FYR 178
           KDKV  ITG   GIG  +    + EG K +   +   + G++      +K+G+    F +
Sbjct: 6   KDKVAIITGGVAGIGLGIAECYVREGAKVVVTANHNVDGGRAAV----AKFGDDVSLFVQ 61

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSI-----GIYKKAIEVNVTALIT 337
            DV+ E  +  +++A + + G +D+++NNA +  +N +I       ++K I+VN+TA   
Sbjct: 62  QDVSKEADWQKVIDATIAKFGRVDILVNNAGIGGVNTAIEDLDLADWQKVIDVNLTANFL 121

Query: 338 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517
               AI+ M K +    G++INVSSVA L    + P Y A+K      ++          
Sbjct: 122 GEKAAIKAM-KQTADAKGSIINVSSVAGLVGLPMAPAYSASKGGSRLLTHATALNLAQRG 180

Query: 518 TGVRVLTVCFGATDTALLTD 577
             +RV +V  G  DT+++ +
Sbjct: 181 IDIRVNSVHPGWIDTSIVPE 200


>UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3;
           Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase -
           Eubacterium sp. (strain VPI 12708)
          Length = 266

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 52/211 (24%), Positives = 105/211 (49%), Gaps = 10/211 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGKSLQVELNSKYGNKTKFYR 178
           KDKV+ +T +  GIG ++ +    EG K ++   ++  E  K+   E+N+  GN  K+  
Sbjct: 4   KDKVILVTASTRGIGLAIAQACAKEGAKVYMGARNL--ERAKARADEMNAAGGN-VKYVY 60

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINN---------AALMNDSIGIYKKAIEVNVTAL 331
           +D T EE ++ ++  +++++G IDV++NN           + N    ++ K + +N+ ++
Sbjct: 61  NDATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSV 120

Query: 332 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHF 511
             ++  A++ M ++    GG++IN+SSV  L        Y  +K+A+   +  +    H 
Sbjct: 121 FIASQTAVKYMAENG---GGSIINISSVGGLIPDISQIAYGTSKAAINYLTKLIA--VHE 175

Query: 512 SKTGVRVLTVCFGATDTALLTDEKLGTFDKY 604
           ++  +R   V  G T T  + D     F  +
Sbjct: 176 ARHNIRCNAVLPGMTATDAVQDNLTDDFRNF 206


>UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
           dehydrogenase/reductase SDR - Solibacter usitatus
           (strain Ellin6076)
          Length = 275

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 59/193 (30%), Positives = 95/193 (49%), Gaps = 6/193 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV F+TG  +G+G ++   L   G   IA+ DI  EA + +   +    G K+   + DV
Sbjct: 7   KVAFVTGGGSGLGRALSEELARRGAV-IAVTDINAEAAEHVAAAITES-GGKSCSMKLDV 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLK 349
           +  E     +++VV   G +D + NNA ++       +G+  + + I+VN+  ++  T  
Sbjct: 65  SQPEDVAASIDSVVGRYGRLDYMFNNAGIIILGEVRDMGLEHWHRLIDVNLLGVLYGTTA 124

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A   M +   G    ++N++SV  L        Y ATK AV+  S  + RPE  SK GVR
Sbjct: 125 AYSHMVRQGYGH---IVNIASVGGLVPLPTYAAYAATKHAVVGLSTSM-RPE-ASKLGVR 179

Query: 530 VLTVCFGATDTAL 568
           +  VC G  +T L
Sbjct: 180 ITVVCPGTMNTGL 192


>UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Bacillus sp. B14905
          Length = 254

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 55/195 (28%), Positives = 95/195 (48%), Gaps = 6/195 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           ++KV  ITG  TGIG+    +   EG K I I DI E++G     ++ + +G +  F   
Sbjct: 7   ENKVAVITGGGTGIGKETALLFAKEGAK-IVITDINEQSGNETVSDIQA-FGGEALFVLH 64

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 343
           DV+NE+ +  + +  +     +D++ NNA       L    +  + + + +NVT +    
Sbjct: 65  DVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGVFLGM 124

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              + +M K +    G+VIN SS+A LT +    +Y A+K AV   +        ++  G
Sbjct: 125 KHIMPLMAKQN---KGSVINASSIAGLTGAAGHVLYGASKGAVRIMTKDAAM--EYAPYG 179

Query: 524 VRVLTVCFGATDTAL 568
           VRV ++  G  DT +
Sbjct: 180 VRVNSIHPGYIDTGM 194


>UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protein;
           n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short
           chain dehydrogenase family protein - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 273

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 6/194 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           DKV  +TG A+G+G +V  +L   G   + I DI  E+ + +   + +  G  T  +  D
Sbjct: 6   DKVFIVTGGASGMGRAVCELLGTRGA-ILIIADIDGESAEKVAAGITAAGGRATGVF-LD 63

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 346
            T +E    +++    E G +D + NNA ++      + S   + + ++VN   ++T TL
Sbjct: 64  TTADETVRRLVDETAAEYGRLDYMFNNAGILIAGEVRDMSDDHWARILDVNFRGVLTGTL 123

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
            A  IM +   G    +IN +S A L    V+  Y  TK AV+  S  + RPE  +K GV
Sbjct: 124 AAYRIMVEQGFGH---IINTASTAGLVPIPVITAYATTKHAVVGLSISL-RPE-AAKAGV 178

Query: 527 RVLTVCFGATDTAL 568
           RV  VC G   T++
Sbjct: 179 RVSVVCPGYVSTSI 192


>UniRef50_Q28GY1 Cluster: Novel protein containing short chain
           dehydrogenase domain; n=4; Deuterostomia|Rep: Novel
           protein containing short chain dehydrogenase domain -
           Xenopus tropicalis (Western clawed frog) (Silurana
           tropicalis)
          Length = 255

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 59/196 (30%), Positives = 95/196 (48%), Gaps = 9/196 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 178
           K +V  +TGA+ GIG +V R+L+  G+K +      ++  K L  E  S     T F Y+
Sbjct: 5   KGRVALVTGASVGIGAAVARVLVQHGMKVVGCARSVDKIEK-LAAECQSAGYPGTLFPYK 63

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 340
            D++NEE  L + +A+     G+DV INNA       L++     ++  I+VNV AL   
Sbjct: 64  CDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVLALSIC 123

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYF--ATKSAVLQFSNCVGRPEHFS 514
           T +A + M K      G +IN++SV           +F  ATK  V   +  + +     
Sbjct: 124 TREAYQSM-KERNIDDGHIININSVLGHIYQCAKQAHFYCATKHTVTALTEAIRQELREL 182

Query: 515 KTGVRVLTVCFGATDT 562
           K+ +RV ++  G  +T
Sbjct: 183 KSHIRVTSISPGLVET 198


>UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep:
           Lin2278 protein - Listeria innocua
          Length = 253

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 51/197 (25%), Positives = 99/197 (50%), Gaps = 8/197 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGAA+G+G+ +  +   EG K + + D+  EA +     +  + G       ++V
Sbjct: 7   KVAVVTGAASGMGQQIAVLFAKEGAK-VVVADLNLEAAQKTVALIEDEQGTALAVV-ANV 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITSTL 346
           T ++    ++N   +  G +D+++NNA +M++ +        ++ K   +N T ++ +T 
Sbjct: 65  TKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRATR 124

Query: 347 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
           KA+ I  +    KG G ++N++S   L  S     Y A+K AV+ F+  VG    ++   
Sbjct: 125 KALHIFEE----KGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVG--FQYANKN 178

Query: 524 VRVLTVCFGATDTALLT 574
           +R   +  GA +T + T
Sbjct: 179 IRCNAIAPGAVNTNIGT 195


>UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii
           KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain
           KSM-K16)
          Length = 247

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 7/204 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +KVV ITG A+GIG + V   L +G K + I D  +E G++   EL    G +  F ++D
Sbjct: 6   NKVVIITGGASGIGRAAVDAFLAKGAK-VVIADFNKETGEAAVKELTDA-GKQVLFVQTD 63

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL--MNDS----IGIYKKAIEVNVTALITSTL 346
           V+NE     ++   V+    +D++INNA    M+ S       Y+K ++V    +   + 
Sbjct: 64  VSNEPSVQNMVAETVKAYERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVFLGSK 123

Query: 347 KAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
            AI+ M K     GG +IN SS+  ++ Q   +P Y A K AV   +  +     ++   
Sbjct: 124 HAIKEMIKTG---GGCIINTSSILGSVAQPEALP-YNAAKGAVNTMTKSLA--VEYADKQ 177

Query: 524 VRVLTVCFGATDTALLTDEKLGTF 595
           +RV  V  G  +TA +  E LG F
Sbjct: 178 IRVNAVAPGFVETAAVNKEALGDF 201


>UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 258

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 61/202 (30%), Positives = 100/202 (49%), Gaps = 8/202 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K+  +TG A+G+G +  R L  EG + +   DI   AG + + EL    G    F R DV
Sbjct: 6   KIALVTGGASGMGLAFTRRLAQEGAR-VYFTDINGAAGHATESELQGA-GLAVVFLRHDV 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-----YKKAIEVNVTALITSTLK 349
           T E  +L +L  +    G +DV++NNA + ++ +I       + + + VN+ ++      
Sbjct: 64  TQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKH 123

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG-- 523
            + +M +    KGG++INVSS+ A+    V   Y A+K+ V   S  V    H ++ G  
Sbjct: 124 GLALMKQ----KGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVAL--HCAEKGYA 177

Query: 524 VRVLTVCFGATDTALLTDEKLG 589
           +RV ++  G  DT LL     G
Sbjct: 178 IRVNSLHPGYIDTPLLAGSNAG 199


>UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=27; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 595

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 59/195 (30%), Positives = 93/195 (47%), Gaps = 7/195 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           KV  +TGA +GIG         EG   +A  +D+A     +L + L    G +    R D
Sbjct: 328 KVAVVTGAGSGIGRCAALAFAREGATIVACDIDLASAERTALLIGLT---GAQAHAKRVD 384

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 346
           V + +    +   V    GG DVVINNA +      ++ S   +++ + VN+  +I  + 
Sbjct: 385 VGSADEMEALATWVGSALGGADVVINNAGIGMAGGILDTSTRHWERILHVNLWGVIHGSR 444

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
              + M     G GG ++N +S AA   S  +P Y  TK+AVL  S C+ R E  ++ G+
Sbjct: 445 LFAQQMAAR--GTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECM-RAE-LAEQGI 500

Query: 527 RVLTVCFGATDTALL 571
            V  VC G  +T ++
Sbjct: 501 GVTAVCPGFAETGIM 515


>UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 252

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 60/191 (31%), Positives = 90/191 (47%), Gaps = 6/191 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITG ATGIG +   +   EG   + I DI EE G S  VE     G    F R DV
Sbjct: 7   KVALITGGATGIGRATALLFAREGA-CVLIGDINEE-GASETVEAVRAAGGDAAFRRCDV 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349
           + EE    ++ A  +E G +DVV  NA L+        S   ++  + +N+TA    T  
Sbjct: 65  SGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLTKY 124

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A  +M +H   +GG++I ++S   L  +     Y A+K  ++  +  +   +  +   +R
Sbjct: 125 AAPVMRRH---EGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLA--DELAPHNIR 179

Query: 530 VLTVCFGATDT 562
           V  VC G  DT
Sbjct: 180 VNCVCPGWVDT 190


>UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2;
           Actinomycetales|Rep: Short chain dehydrogenase -
           Rhodococcus sp. (strain RHA1)
          Length = 267

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 57/190 (30%), Positives = 93/190 (48%), Gaps = 7/190 (3%)
 Frame = +2

Query: 20  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTNEE 199
           +TG A G+G  +   L D G   + I D+ EE G++    +  K G  T F + DVT++ 
Sbjct: 13  VTGGAKGLGAGMAAALADAGAA-VVIGDVLEEEGRATADSVG-KTGVDTGFVKLDVTDDG 70

Query: 200 HFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLKAIEI 361
           ++   + A V++ GG+D+++NNA +   S+ +       ++  EVN+  +       +  
Sbjct: 71  NWERAVAATVEQLGGLDLLVNNAGIEISSLVVDIDPADIRRMCEVNILGVALGLKHGLRA 130

Query: 362 MGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
           M    + G GG ++NVSSVAA      +  Y ATKSAV + +    +       GVRV  
Sbjct: 131 MRPGGAAGSGGAIVNVSSVAATIPFPGIAGYSATKSAVDRLTRVAAQEAGKLGYGVRVNC 190

Query: 539 VCFGATDTAL 568
           V  G   T +
Sbjct: 191 VYPGLVATEM 200


>UniRef50_Q46PX5 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR; n=2; Bacteria|Rep:
           NAD-dependent epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR - Ralstonia eutropha (strain
           JMP134) (Alcaligenes eutrophus)
          Length = 253

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 7/197 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDKV  +TG A+GIGE+ VR+   +G   + I D     G+ L  EL S+      +   
Sbjct: 9   KDKVAIVTGGASGIGEATVRLFASQGAS-VVIAD-RSALGEKLAREL-SESSLAAHYSEV 65

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 340
           DV+ E+    +++  V   G +D+++ NA + + S  +       +++ I+VN+T +  S
Sbjct: 66  DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
              AI  M K   G GG ++N++S+           Y A K  V+  +  +G   H ++ 
Sbjct: 126 NKLAIVQMKKQ--GTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLG-VSH-AQD 181

Query: 521 GVRVLTVCFGATDTALL 571
           G+RV  VC G   T L+
Sbjct: 182 GIRVNAVCPGFVATPLI 198


>UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase
           SDR - Pelobacter propionicus (strain DSM 2379)
          Length = 283

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 57/206 (27%), Positives = 102/206 (49%), Gaps = 10/206 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITGA  GIG ++   L  +G   + + D+  +    +  E+ ++ G K    R+DV
Sbjct: 24  KVAIITGAGRGIGRAIALRLGADGAAMV-VSDVNGDNATKVAEEIKAR-GGKAMALRTDV 81

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVT-ALITSTL 346
           T+E     +++  V++ G +D+++ NA + N  + I      + + + VN   A +  T+
Sbjct: 82  TSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAEWDQIMAVNTKGAFLCDTM 141

Query: 347 KAIEIMGK-HSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517
            A +++ + HS   G GG +IN +S+AA +   ++  Y A+K AV  F+  + +     K
Sbjct: 142 AARQMIKQGHSETPGSGGKIINCASIAAHSGFSILAAYSASKFAVRGFTQALAKELGPYK 201

Query: 518 TGVRVLTVCFGATDTALLTDEKLGTF 595
             V         TD   L DEK+G +
Sbjct: 202 INVNAYCPGIVGTDMWTLIDEKMGPY 227


>UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2;
           Euryarchaeota|Rep: Predicted short chain dehydrogenase -
           Methanosphaera stadtmanae (strain DSM 3091)
          Length = 253

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K KV  ITGA  GIG+S+  +  +EG   I I    E   + +  E+NS  G+ +     
Sbjct: 4   KGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERL-EQITNEINSNGGDASACI-G 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 340
           DVT +E    ++   + + G ID+++NNA +M+D + +       + K I+VN+T  +  
Sbjct: 62  DVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRL 121

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               I  M K++   GG +I +SSV  L        Y A+K  V+  +        + K 
Sbjct: 122 IRAVIPEMIKNN---GGNIITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWV--YGKH 176

Query: 521 GVRVLTVCFGATDTALLTDEKLGTFD 598
            +R   +  G  +T + T    G  D
Sbjct: 177 NIRSNVIAPGTVNTEIATTINPGRMD 202


>UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Pseudoalteromonas
           atlantica (strain T6c / BAA-1087)
          Length = 270

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 9/198 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K KV+ ITG ATGIG  +V   + +  + +  +D+ EEA  +L  +L+++ G    F   
Sbjct: 26  KGKVILITGGATGIGAVMVEAFMRQQAR-VLFVDVQEEAAHALCSKLHAELGAAPIFKNL 84

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 340
           D T+ +     ++++    G +DV+INN A       L  D  G ++  + VN+ +   +
Sbjct: 85  DTTHIDELQAFISSIGHSHGRLDVLINNVANDTRHSPLDIDQQG-WRDCMAVNLDSTFFA 143

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
              AI +M      + G +IN+SS+  L     MP Y A KSA+   S  +     + + 
Sbjct: 144 CQSAIRLM---RDKRTGNIINMSSINVLIGPKQMPGYVAAKSALNGLSKSLA--NQYGEY 198

Query: 521 GVRVLTVCFG--ATDTAL 568
           G+RV T+  G  ATD  L
Sbjct: 199 GIRVNTILPGWVATDRQL 216


>UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: ARP
           protein - Arabidopsis thaliana (Mouse-ear cress)
          Length = 629

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 66/221 (29%), Positives = 105/221 (47%), Gaps = 20/221 (9%)
 Frame = +2

Query: 20  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNKTKF-----Y 175
           +TG A+GIG ++   L ++GV  + + D +EE G+   SL  E N+K+     F      
Sbjct: 11  VTGGASGIGRALCLALAEKGV-FVTVADFSEEKGQETTSLVREANAKFHQGLSFPSAIFV 69

Query: 176 RSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMN---------DSIGIYKKAIEVNVTA 328
           + DVTN    L   +  +   G +D+ INNA +           D    +K  I V++ A
Sbjct: 70  KCDVTNRGDLLAAFDKHLATFGTLDICINNAGISTPLRFDKDDTDGSKSWKHTINVDLIA 129

Query: 329 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEH 508
           ++  T  AI+ M      K G +IN+ S A L    V PIY A+K+ V+ F+  +    +
Sbjct: 130 VVEGTQLAIKAMKAKQ--KPGVIINMGSAAGLYPMPVDPIYAASKAGVVLFTRSLA---Y 184

Query: 509 FSKTGVRVLTVC--FGATDTALLTDEK-LGTFDKYLEFFML 622
           + + G+R+  +C  F  TD A   D   L +   Y+   ML
Sbjct: 185 YRRQGIRINVLCPEFIKTDLAEAIDASILESIGGYMSMDML 225


>UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 387

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 60/214 (28%), Positives = 105/214 (49%), Gaps = 20/214 (9%)
 Frame = +2

Query: 41  IGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNK-----TKFYRSDVTNE 196
           IG+++   L ++G+  + ++D +EE GK   SL  + N+K+  K       F R DVTN 
Sbjct: 36  IGKAISLALGEKGI-FVTVVDFSEEGGKEVASLVEKENAKFHPKLGFPSAMFIRCDVTNT 94

Query: 197 EHFLGILNAVVQEQGGIDVVINNAAL---------MNDSIGIYKKAIEVNVTALITSTLK 349
                     +   GG+D+ +N+A +           ++ G++++ I VN+ A+I  T  
Sbjct: 95  RELAAAFKKHLATYGGLDICVNSAGIGTHEPFHKDQTENSGLWRRTINVNLVAVIDCTRL 154

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           AI+ M   +  K G +IN+ S + L   +V PIY A+K  V+ F+  +     + + G+R
Sbjct: 155 AIQTM--QAAKKPGVIINMGSASGLYPMYVDPIYSASKGGVVLFTRSLA---PYKRHGIR 209

Query: 530 VLTVC--FGATDTALLTDEK-LGTFDKYLEFFML 622
           V  +C  F  T+     D K +G    Y+   M+
Sbjct: 210 VNVLCPEFVQTEMGSSVDSKFIGLMGGYVSMEMV 243


>UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Rep:
           Fat body protein 2 - Drosophila melanogaster (Fruit fly)
          Length = 256

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 54/190 (28%), Positives = 94/190 (49%), Gaps = 2/190 (1%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTKFYRS 181
           K V   G+ +GIG  ++  L+ + +K + I+   E  E  K LQ  +N     K  F + 
Sbjct: 7   KNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMENVEMMKKLQA-INPSV--KVVFMQM 63

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           ++  +      +  + Q  G IDV+IN   ++ D     +  + +N+T +I ST+ A+  
Sbjct: 64  NLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKD--VETTMGMNLTGMIQSTMMAMPY 121

Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541
           M K   G GG V+N+SSV  L  +    +Y A    +L F+  +G    + KTGV  + +
Sbjct: 122 MDKTQMGMGGMVVNMSSVYGLEPAPAFAVYAAAMHGILGFTRSMGDKMIYQKTGVMFMAM 181

Query: 542 CFGATDTALL 571
           C G T++ ++
Sbjct: 182 CPGLTNSEMI 191


>UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=4;
           Burkholderiales|Rep: 3-beta-hydroxysteroid dehydrogenase
           - Comamonas testosteroni (Pseudomonas testosteroni)
          Length = 254

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 50/161 (31%), Positives = 89/161 (55%), Gaps = 6/161 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG A+G+G  VV++LL EG K +A  DI E AG+ L  EL    G ++ F R DV
Sbjct: 8   KVALVTGGASGVGLEVVKLLLGEGAK-VAFSDINEAAGQQLAAEL----GERSMFVRHDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 349
           ++E  +  ++ AV +  G ++V++NNA ++         +  + + +++N  ++     +
Sbjct: 63  SSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQQ 122

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 472
            I  M +     GG++IN++SV++         Y A+K+AV
Sbjct: 123 GIAAMKE----TGGSIINMASVSSWLPIEQYAGYSASKAAV 159


>UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular
           organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus
           iheyensis
          Length = 256

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 59/197 (29%), Positives = 94/197 (47%), Gaps = 7/197 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +DKV  +TGAA G+G++   IL  E    + I D  EE G+ + VE   + G +  F + 
Sbjct: 7   EDKVAIVTGAAMGMGKATA-ILFAESKAKVVIADFNEEKGQEV-VEEVKQAGGQAAFIKV 64

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 340
           D+++      ++   V + G +D+ +NNAAL  D           + K I V++T   T+
Sbjct: 65  DISDSAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTG--TA 122

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
                E+      G GG+++N+SSV+          Y A K  V+  +  V   E+    
Sbjct: 123 LCMKYELQQLLEQGNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTK-VAALEN-GPQ 180

Query: 521 GVRVLTVCFGATDTALL 571
            +RV TV  GA DT +L
Sbjct: 181 NIRVNTVAPGAIDTPML 197


>UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep:
           CylG - Streptococcus agalactiae
          Length = 240

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 52/197 (26%), Positives = 96/197 (48%), Gaps = 7/197 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG   GIG ++ + L  EG K IAI +  +   ++LQ EL      K   Y+ ++
Sbjct: 2   KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEEL-----PKLDVYKCNI 56

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349
           ++ +    ++  + +E GGID ++NNA ++ D   +      +   I +N+  L+  +  
Sbjct: 57  SDAKAVQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKA 116

Query: 350 AIEIM-GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
            ++IM  K   GK   VIN+SS + +        Y ATK A++  +  + +   F+  G+
Sbjct: 117 VLKIMKAKRIQGK---VINISSTSGIAGQIGQANYSATKGAIISITKTLAK--EFASDGI 171

Query: 527 RVLTVCFGATDTALLTD 577
            +  V  G  +T +  +
Sbjct: 172 TINCVSPGFIETDMTNE 188


>UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Short chain dehydrogenase -
           marine gamma proteobacterium HTCC2143
          Length = 259

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 52/203 (25%), Positives = 92/203 (45%), Gaps = 5/203 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +V  +TG A GIG +       EG+ ++ + D+ ++ G+     + +  GN   F   DV
Sbjct: 8   QVALVTGGAAGIGRTTAAAFAREGL-NVVVADMDKDGGEETVAAIKAAGGNAI-FVPCDV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367
           T E     ++       G +D   NNA +  +  G   K  E    +++   +K + +  
Sbjct: 66  TKESDVQWLIETTCSTYGSVDYAFNNAGIDIEK-GELSKGTEDEFDSIMAVNVKGVWLCM 124

Query: 368 KHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           KH   +     GGT++N SS+  L  +  M IY A+K AV+  +         ++ G+R+
Sbjct: 125 KHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVEN--ARNGIRI 182

Query: 533 LTVCFGATDTALLTDEKLGTFDK 601
             VC G  DT +    ++  FD+
Sbjct: 183 NAVCPGVIDTNMFNRSRM--FDR 203


>UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Candidatus Methanoregula boonei 6A8|Rep:
           Short-chain dehydrogenase/reductase SDR - Methanoregula
           boonei (strain 6A8)
          Length = 253

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 56/212 (26%), Positives = 98/212 (46%), Gaps = 6/212 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV+ +TGA+ GIG +   +      + I       +  +SL  E+ +  G+     R+DV
Sbjct: 12  KVILVTGASRGIGRATAFLAAKNHAQVIVNYQKHADQAESLVSEITA-LGHSAMAIRADV 70

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 349
           T EE    +   + ++ G +D+++NNA +M ++      I  Y+  ++VN       T  
Sbjct: 71  TCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNCKGTFLCTQH 130

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A +IM +    K GT+IN++SV  +  +     Y ++KS V+ F+ C  +        + 
Sbjct: 131 AAKIMVRQ---KAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAK--ELGAFNIT 185

Query: 530 VLTVCFGATDTALLTDEKLGTFDKYLEFFMLG 625
           V  V  G  DT L  D +    +  L+   LG
Sbjct: 186 VNAVAPGFIDTDLTADTRSQVKEDILKNIALG 217


>UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4;
           Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella
           melitensis
          Length = 272

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 57/196 (29%), Positives = 94/196 (47%), Gaps = 6/196 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDKVV +TG A+GIGE+  R  + EG K + I D ++  G+ L  EL   +  +  F ++
Sbjct: 4   KDKVVIVTGGASGIGEATARAFIREGAK-VVIADFSDH-GQQLADELAGAH-EQALFIKT 60

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITST 343
           DV +      ++   V+  G +D++  NA +  D+         ++K I++N+T +    
Sbjct: 61  DVADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVYLCD 120

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             AI+ M   S G GG ++N  S+ +      +  Y A K  V   +  +     +    
Sbjct: 121 KYAIDQM--RSQG-GGVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLA--IDYGPQN 175

Query: 524 VRVLTVCFGATDTALL 571
           +RV  VC G  DT LL
Sbjct: 176 IRVNAVCPGYIDTPLL 191


>UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR)
           family protein; n=1; Thermobifida fusca YX|Rep:
           Short-chain dehydrogenase/reductase (SDR) family protein
           - Thermobifida fusca (strain YX)
          Length = 282

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 57/189 (30%), Positives = 91/189 (48%), Gaps = 5/189 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           + +V  ITG A+GIGE+ VR    EG   + I DI  EAG+ L  EL    G++  F R+
Sbjct: 6   RGRVAAITGGASGIGEATVRRFHTEGAS-VVIADIQAEAGRRLADEL----GDRAVFVRT 60

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           DV+ E     +++  V   G +D+++NNA +M  ++G        +    I   L+ +  
Sbjct: 61  DVSEEADVAALVDTAVDRFGQLDIMVNNAGIMG-ALGPIDATRMSDADLTIAVNLRGVIC 119

Query: 362 MGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             KH+       + G +I+ SS A +       IY A K  ++  SN V       + G+
Sbjct: 120 GMKHAARVMKPRRSGVIISTSSPAGVLGGIGPHIYSAVKVGIIGLSNSVA--AELRQHGI 177

Query: 527 RVLTVCFGA 553
           RV T+  G+
Sbjct: 178 RVNTIIPGS 186


>UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 262

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 48/164 (29%), Positives = 84/164 (51%), Gaps = 7/164 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           + KV  ITG A GIG    R L   G   +AILD+  +  ++L  E+ ++ G +  F+  
Sbjct: 11  RGKVAAITGGARGIGAETARTLAAAGAS-VAILDVLSQPAEALVEEIRAQ-GGQAAFWSL 68

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITS 340
           DVT+E     +   +V   G +DV++NNA +   ++         +++ ++VNV  +   
Sbjct: 69  DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 472
           T  AI  +       GG+++N+SS+  +     +P Y A+K+AV
Sbjct: 129 TRAAIPHI---DAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAV 169


>UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=3; Clostridium
           perfringens|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family - Clostridium perfringens
           (strain ATCC 13124 / NCTC 8237 / Type A)
          Length = 272

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 57/195 (29%), Positives = 96/195 (49%), Gaps = 7/195 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           DKV+ ITGAA GIG++V      EG K + + D  EE  K    E+     N  +F   D
Sbjct: 11  DKVMIITGAAGGIGKAVALRAAKEGAK-LVLADRKEEMSKETLKEIREITSN-VEFLICD 68

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITST 343
           +   E+   +++  +++ GG+D++INNA +          S  +++  ++ N+      +
Sbjct: 69  LREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFHCS 128

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              I+ M K +  KGG ++NVSSVA LT       Y  +K  +   +  +     +++ G
Sbjct: 129 HYGIQEMIKQN--KGGAIVNVSSVAGLTGFPGHSAYVTSKHGLNGLTRNMAL--DYARYG 184

Query: 524 VRVLTVCFGATDTAL 568
           +RV  V  G TDT +
Sbjct: 185 IRVNAVNPGTTDTPM 199


>UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;
           n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
           FadB2x - Pseudomonas stutzeri (strain A1501)
          Length = 258

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 71/230 (30%), Positives = 106/230 (46%), Gaps = 18/230 (7%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +DKVV ITG A+G+G +    L  E    IAI D+  EAG+     L ++   +  F  +
Sbjct: 4   QDKVVVITGGASGLGLATAHYLAAEKGARIAIFDLNVEAGEQAVAALGTE---RAMFVAT 60

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND-----------SIGIYKKAIEVNVTA 328
           DV++EE     ++AV+   G I V IN AA+               +  + +A  +N+  
Sbjct: 61  DVSSEESVQNAVDAVMANFGAIHVCINGAAVPTGFKILGKEGKAAPLARFAQATAINLNG 120

Query: 329 LITSTLKAIEIMGKH---SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499
           +     K  E M K+   +G + G VINVSS AA         Y ATK+ V+  +    R
Sbjct: 121 VFNVMSKCAEHMAKNEAEAGEERGVVINVSSGAAYEGQLGQCAYSATKAGVIGLNMPAAR 180

Query: 500 PEHFSKTGVRVLTVC---FGATDTALLTDEKLGTFDKYLEF-FMLGPTKE 637
                  GVRV  +    F  T  A L ++ LG+  + +E    LG T+E
Sbjct: 181 --ELGAIGVRVNAIAPGLFLTTMVAALDEKVLGSLKEQMEAPKRLGDTRE 228


>UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Thermotoga|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Thermotoga maritima
          Length = 257

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 8/198 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K KV  +TG   GIG+++ + L   G   + I+DI EE  +    E+  K G +  FY  
Sbjct: 11  KRKVALVTGGGQGIGKAIAQALAAAGAA-VLIMDINEETARRTVEEIKEK-GGEADFYVG 68

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 343
           DVT EE   G +   +   G +D+ +NNA +       N  +  +KK I+VN+  +  S 
Sbjct: 69  DVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSA 128

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517
                 M +   GK   +IN++S++   + +      Y A+K+ V+  +  +     ++ 
Sbjct: 129 KAEFHAMKERKYGK---IINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLA--AEWAP 183

Query: 518 TGVRVLTVCFGATDTALL 571
            G+RV ++  G   T L+
Sbjct: 184 YGIRVNSISPGYIRTPLI 201


>UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=6;
           Clostridium|Rep: Predicted short-chain dehydrogenase -
           Clostridium acetobutylicum
          Length = 262

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 51/188 (27%), Positives = 94/188 (50%), Gaps = 5/188 (2%)
 Frame = +2

Query: 14  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193
           V ITGA+TGIG  + RI    G  +  ++   +E  K L +EL      K    + D++ 
Sbjct: 3   VLITGASTGIGYEITRIFARNG--YDVVITARDE--KRL-IELAKNINTKVTVIKKDLSR 57

Query: 194 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 373
            +    + N + +    +D+++NNA  M D+ G++ K+    +  ++   +K++ I+ + 
Sbjct: 58  PDSANELFNEIKENNIEVDILVNNAG-MGDT-GLFHKSSVDKINEMLELNIKSLTILTRL 115

Query: 374 SGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
                   + G ++NV+S  +      + +Y+ATK+ VL F+  +G  E   K  V+V  
Sbjct: 116 VSAEMVKKRSGMILNVASTGSYMPGPFIAVYYATKAYVLSFTEAIG--EELKKFNVKVSA 173

Query: 539 VCFGATDT 562
           +C GAT T
Sbjct: 174 LCPGATAT 181


>UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Staphylococcus
           epidermidis|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Staphylococcus
           epidermidis (strain ATCC 35984 / RP62A)
          Length = 255

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 53/188 (28%), Positives = 101/188 (53%), Gaps = 7/188 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  + G ATGIG+++   L   G  +I I D+    G+     ++++ G KT   + D+
Sbjct: 13  KVAMVIGGATGIGKAMAEALAQAGA-NIVIADLQSNIGQETATTISTQSGVKTTSLKLDI 71

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGI-YKKAI-EVNVTALITSTLKAI 355
           T+ +    I++ VV+E G ID+++NNA  ++ +D+  I Y++ + E+N++  +       
Sbjct: 72  THSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLS--LNGAFSVA 129

Query: 356 EIMGKHSGGKG-GTVINVSSVAAL--TQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
           + +G+    KG G++INVSSV  L   ++     Y  +K+ V   +  + R   +S+ G+
Sbjct: 130 QTVGRQMIEKGSGSIINVSSVLGLIANKTQDQSSYETSKAGVTMLTKSLAR--EWSRYGI 187

Query: 527 RVLTVCFG 550
           +V  +  G
Sbjct: 188 KVNAIAPG 195


>UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase;
           n=1; Burkholderia xenovorans LB400|Rep: Putative
           short-chain type dehydrogenase - Burkholderia xenovorans
           (strain LB400)
          Length = 252

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 61/192 (31%), Positives = 91/192 (47%), Gaps = 6/192 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K + ITGA   IG+   R  + EG + + I DIAEEAG+++  EL    G    F + DV
Sbjct: 8   KRIIITGAIGNIGKEAARGFIAEGAR-VVIGDIAEEAGRAVAAEL----GAAAHFVQVDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367
           T+E     ++   V+  GG+D +  NA L     G      + N  AL     +A     
Sbjct: 63  TSEASVANLIARGVEWLGGLDALAQNAGLQRS--GAIAGFEQANWDALFAVNARAHFFGA 120

Query: 368 KHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           KH+       GK G++IN+SS+A       +  Y A+K AV+ F+  +      +   +R
Sbjct: 121 KHAIPHLQRSGK-GSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALAL--ELAPDNIR 177

Query: 530 VLTVCFGATDTA 565
           V  +C G  DTA
Sbjct: 178 VNAICPGWVDTA 189


>UniRef50_Q2UEK6 Cluster: Dehydrogenases with different
           specificities; n=2; Aspergillus|Rep: Dehydrogenases with
           different specificities - Aspergillus oryzae
          Length = 261

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 56/203 (27%), Positives = 96/203 (47%), Gaps = 9/203 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGA +GIG      L + G  ++ + +  E  GK    +++++ G++  F  +DV
Sbjct: 13  KVAIVTGAGSGIGRETALCLANAGA-NVVVAEANETTGKETAAKVSAQTGSRGLFILTDV 71

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346
           +  E    ++ A ++  G +D+ +NNAAL  D+  I       ++K I VN+   +   L
Sbjct: 72  SRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVG-VAFCL 130

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
           K  E+      G GG++IN+SS         M  Y A K  +   +          + G+
Sbjct: 131 K-WELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQTAAVEN--GRHGI 187

Query: 527 RVLTVCFG--ATDTALLTDEKLG 589
           RV  +  G  ATD  + T ++LG
Sbjct: 188 RVNALAPGGVATDLTMATMQELG 210


>UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase,
           putative glucose-1-dehydrogenase; n=1; Pyrococcus
           abyssi|Rep: Short-chain alcohol dehydrogenase, putative
           glucose-1-dehydrogenase - Pyrococcus abyssi
          Length = 240

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 58/200 (29%), Positives = 97/200 (48%), Gaps = 7/200 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K KV  ITGA+ GIG ++   L   GV  +      EE  K  + EL  +YG +T   ++
Sbjct: 4   KGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTE-ELCRQYGVETLLVKA 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALITS 340
           DV+N E    ++  V+ + G ID++INNA ++    D + +    + + I VN+      
Sbjct: 63  DVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAFIV 122

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
           T + +  M      K G ++N++S+A      V P Y A+K  ++  +  + R  H +  
Sbjct: 123 TQEVLRYM------KKGKIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLAR--HLA-P 173

Query: 521 GVRVLTVCFGATDTALLTDE 580
            + V  V  G  DT +L+ E
Sbjct: 174 NILVNAVAPGPVDTDMLSSE 193


>UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=4; Sphingomonas|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Pseudomonas paucimobilis (Sphingomonas paucimobilis)
          Length = 250

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 61/193 (31%), Positives = 94/193 (48%), Gaps = 6/193 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITG A+G+G +  +   +EG K + I D+ EE  K +  E+ +  G    F R DV
Sbjct: 8   KVALITGGASGLGAAQAKRFAEEGAK-VVIGDLNEEMAKGVVAEIRAA-GGDALFIRLDV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349
           T+   +   + A V   GG+  + N A +++      +SI  + K + VN TA+      
Sbjct: 66  TDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTAIFLGIKA 125

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           AI  + K SG   G++IN+SS+  +  +     Y ATK+AV   S        F   GVR
Sbjct: 126 AIPELVK-SG--NGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAAL--EFVDRGVR 180

Query: 530 VLTVCFGATDTAL 568
           V T+  G  +T +
Sbjct: 181 VNTIVPGGMNTPI 193


>UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=225; cellular organisms|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio
           cholerae
          Length = 244

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 60/201 (29%), Positives = 97/201 (48%), Gaps = 9/201 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGA+ GIG+++  +L + G K I       E+G      ++   G+  K    +V
Sbjct: 6   KVALVTGASRGIGKAIAELLAERGAKVIGTA--TSESGAQA---ISDYLGDNGKGMALNV 60

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITSTLK 349
           TN E    +L A+  E GG+D+++NNA +  D++ +  K       +E N+T++   +  
Sbjct: 61  TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 120

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            +  M K    + G +INV SV     +     Y A K+ V+ F+  + R    +  GV 
Sbjct: 121 VLRGMMKK---RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAR--EVASRGVT 175

Query: 530 VLTVC--FGATD-TALLTDEK 583
           V TV   F  TD T  L DE+
Sbjct: 176 VNTVAPGFIETDMTKALNDEQ 196


>UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20;
           Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Oceanobacillus iheyensis
          Length = 255

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 65/202 (32%), Positives = 100/202 (49%), Gaps = 13/202 (6%)
 Frame = +2

Query: 20  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTNEE 199
           +TG A+G+GE+ VR L ++G K +AI D+ +E G+ L  EL    G+   +++ DVT+E 
Sbjct: 10  VTGGASGLGEATVRRLHNQGGK-VAIFDLNKENGERLATEL----GDNVDYFQVDVTDET 64

Query: 200 HFLGILNAVVQEQGGIDVVINNA--ALMNDSIG--------IYKKAIEVNVTALITSTLK 349
                L+ V+++  GI  V+N A  A+   +IG         +   IE+N+         
Sbjct: 65  SVQKALDNVMEQSDGIHAVVNCAGIAIAEKTIGKKGVHSLQHFSNVIEINLIGTFNVIRL 124

Query: 350 AIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
           A E M  +S    G+ G +IN +SVAA         Y A+K  V   +  + R    S  
Sbjct: 125 AAEKMALNSPNDEGERGVIINTASVAAFEGQIGQAAYSASKGGVAGMTLPIAR--DLSTL 182

Query: 521 GVRVLTVCFGATDTALLTDEKL 586
           G+RV+T+  G   T L   EKL
Sbjct: 183 GIRVMTIAPGLFLTPLF--EKL 202


>UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=3; Proteobacteria|Rep: 3-ketoacyl-acyl carrier protein
           reductase - Pseudoalteromonas haloplanktis (strain TAC
           125)
          Length = 247

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 57/198 (28%), Positives = 96/198 (48%), Gaps = 6/198 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +D+VV +TGA  GIG+S+V      G  ++A +DI  +   +   ELN+          +
Sbjct: 4   QDQVVLVTGAGQGIGQSIVSYFATAGA-NVAAVDINADTLNASVNELNANVAGNIVAITA 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITST 343
           ++   +     + AVV++ G +D +IN A      A ++     + K I VN+T      
Sbjct: 63  NIAKSDSVRDAIAAVVEKFGRLDAIINVAGVGSIDAFVDTPDEHWDKVIAVNLTGTFLCC 122

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
            +A ++M        G +INVSS AALT       Y A+K+ V+  +  + R    +  G
Sbjct: 123 REAAKVMQAQG---SGCIINVSSTAALT-GEGPSHYCASKAGVMGLTRSMAR--ELAPVG 176

Query: 524 VRVLTVCFGATDTALLTD 577
           +RV T+  G T+T ++ D
Sbjct: 177 IRVNTIVPGPTNTPMMAD 194


>UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein)
           reductase; n=1; Bacillus sp. SG-1|Rep:
           3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus
           sp. SG-1
          Length = 246

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 55/195 (28%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K+K   ITG+A GIG +  +    EG K + + D  E  G + + E   + G  T FY+ 
Sbjct: 4   KNKTAVITGSANGIGLAAAKKFAQEGCK-VIMADYDENKGAA-EAEKLQEEGGDTVFYQV 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 343
           DV N E    +   V+++ G ID++INNA +  D++        +++ ++VN+T +   T
Sbjct: 62  DVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVFHCT 121

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              +  +   + GK G +IN +S + L  +     Y A+K+AV+  +    +   F   G
Sbjct: 122 QALLPAL--INSGK-GKIINTASASGLYGNVGQTNYAASKAAVIGMTKTWAK--EFGPKG 176

Query: 524 VRVLTVCFGATDTAL 568
           + V  V  G  +T +
Sbjct: 177 INVNAVAPGVIETEM 191


>UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Marinomonas sp. MED121|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinomonas sp. MED121
          Length = 255

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 60/206 (29%), Positives = 100/206 (48%), Gaps = 7/206 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KD+VV ITGA+ G+G+   +    +G K +A+ D+   A   L  EL  + G +      
Sbjct: 5   KDQVVLITGASGGLGKEAAKQFAQQGAK-LALCDLNVAALNDLGTELIEQ-GYEVFSQPC 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 340
           DV+NE+     ++      G +DV INNA        L +     +++ +++NV  +   
Sbjct: 63  DVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYLC 122

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               I  M K  GG    + N+SSVA ++ +  M  Y A+K AV+  +  V     + + 
Sbjct: 123 MKYQIPHMIKQGGG---AICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVA--HEYGRA 177

Query: 521 GVRVLTVCFGATDTALLTDEKLGTFD 598
           G+RV +VC   T T ++ ++ L T D
Sbjct: 178 GIRVNSVCPYITMTDMV-EQHLKTLD 202


>UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=5; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Mycobacterium
           sp. (strain KMS)
          Length = 261

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 57/200 (28%), Positives = 93/200 (46%), Gaps = 8/200 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +V  +TG A+GIG +    L  EG++ + +LDI   A +++   +    G      R DV
Sbjct: 6   RVALVTGGASGIGRATAGRLAAEGMR-VCVLDIDGPATEAVAESIGG-IG-----LRCDV 58

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND---SIGI-----YKKAIEVNVTALITST 343
           T+ E      +  V E GG+DV   NA +  D    IG      Y+K++ VNV  ++   
Sbjct: 59  TDPEQVDSAFDTCVAELGGVDVAFLNAGITIDWSGDIGALDLAQYRKSVGVNVDGVVFGV 118

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             A+  M     G    ++  +S+A L   H  P+Y   K  V+ F   +    + +  G
Sbjct: 119 RAAVRTMRTLDPGVDRAILATASLAGLMPWHPDPVYSLGKHGVVGFMRSIA--PNLAAEG 176

Query: 524 VRVLTVCFGATDTALLTDEK 583
           + V T+C G T+T +L D +
Sbjct: 177 IAVHTICPGITETGVLGDRR 196


>UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Shewanella pealeana ATCC 700345|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella pealeana ATCC
           700345
          Length = 254

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 55/184 (29%), Positives = 97/184 (52%), Gaps = 6/184 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITGAA G+G +  R++  EG + + + DI  E GK    E+ +  GN + F   DV
Sbjct: 8   KVALITGAARGVGLATARLMAREGAQ-VVLTDINAEQGK----EIANSIGNNSLFIEHDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 349
           T E  +  ++N +  + G +++++NNAA++       +++  +++   VN  ++      
Sbjct: 63  TKEADWSAVINHIEAKFGQLNILLNNAAILQLGDIKEETLAGWQRVHMVNSDSVFLRIHY 122

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A+ +M K SG  GG++IN+SS +A+        Y A+K+A+   S  V      +K  VR
Sbjct: 123 ALPLMEK-SG--GGSIINMSSSSAVFGMPHFAAYGASKAAIRGLSQSVAVYCSQTKNNVR 179

Query: 530 VLTV 541
             T+
Sbjct: 180 CNTL 183


>UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase family
           protein; n=1; Gramella forsetii KT0803|Rep: Short-chain
           dehydrogenase/reductase family protein - Gramella
           forsetii (strain KT0803)
          Length = 271

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 52/200 (26%), Positives = 102/200 (51%), Gaps = 6/200 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           ++K V ITG A+GIG  + +  +++G   + ILDI + A + ++++L +       F  +
Sbjct: 5   RNKTVLITGGASGIGLLLTKFSIEKGASALIILDIDKPALQQVELQLKTNICQILSF-ET 63

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 343
           D++NE      +  +  +   +D++INNA ++        ++    + ++VN  A +  T
Sbjct: 64  DLSNEIQIENAVKKITAQNLQVDILINNAGVVTGKNFSEHNLEDIDRNMQVNAIAPMKLT 123

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              +  M K    K G ++N+SS A++  +  M +Y A+K A+  +S+ +       +TG
Sbjct: 124 KLLLPEMLKR---KSGHIVNISSAASMLSNPGMSVYCASKWAMTGWSDSLRLEMERERTG 180

Query: 524 VRVLTVCFGATDTALLTDEK 583
           ++VLTV     DT +    K
Sbjct: 181 IKVLTVTPYYIDTGMFEGVK 200


>UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Chloroflexus|Rep: Short-chain
           dehydrogenase/reductase SDR - Chloroflexus aggregans DSM
           9485
          Length = 256

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 58/194 (29%), Positives = 95/194 (48%), Gaps = 6/194 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG A GIG +    L  EG   + I D  + A  +  VE  + +G +     +DV
Sbjct: 6   KVAIVTGGAQGIGRATALALAREGAA-VVIAD-RDAAATTALVEGINAWGGRALAVIADV 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 349
           ++E     I N  V E GGID+++NNA +       + ++ ++++ I VN+T +    L 
Sbjct: 64  SDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVF---LV 120

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           +  +M +     GG ++NV+SV  L        Y A+K  V+  +  +      +  G+R
Sbjct: 121 SRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDG--APDGIR 178

Query: 530 VLTVCFGATDTALL 571
           V  VC G  DT+LL
Sbjct: 179 VNCVCPGLIDTSLL 192


>UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain
            dehydrogenase/reductase family protein; n=1; Tetrahymena
            thermophila SB210|Rep: Oxidoreductase, short chain
            dehydrogenase/reductase family protein - Tetrahymena
            thermophila SB210
          Length = 843

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 57/192 (29%), Positives = 94/192 (48%), Gaps = 6/192 (3%)
 Frame = +2

Query: 14   VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193
            V +TGAA G G+ +      +   +I I DI E+    +  E+  K G K  FY+ DV++
Sbjct: 577  VLLTGAAMGAGKFLAMNFAKKNNCNIIIYDIREDLMGQVIEEIQ-KAGAKGYFYKCDVSD 635

Query: 194  EEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLKAI 355
            E+     + + +Q+   ID++INN  + N       S    +KA  VN  A ++   K +
Sbjct: 636  EQELQRTVESTLQKFQKIDILINNVGIANLKLFTDVSFDEVQKAFSVNFLAPVSIIKKIL 695

Query: 356  EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
             +M + + G    ++NVSSVA+L  S  M  Y A+K+A+  F N +       K  +   
Sbjct: 696  PVMIERNQGH---IVNVSSVASLMPSAKMTDYCASKAALSGFHNALRLELKQQKKNINTT 752

Query: 536  TVCFGATDTALL 571
             +C  A +T +L
Sbjct: 753  LICPYAVNTGVL 764


>UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase, chloroplast precursor; n=80; cellular
           organisms|Rep: 3-oxoacyl-[acyl-carrier-protein]
           reductase, chloroplast precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 319

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 60/198 (30%), Positives = 97/198 (48%), Gaps = 8/198 (4%)
 Frame = +2

Query: 11  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELN-SKYGNKTKFYRSDV 187
           VV ITGA+ GIG+++   L   G K   +++ A  A ++ +V     +YG +   +  DV
Sbjct: 78  VVVITGASRGIGKAIALALGKAGCK--VLVNYARSAKEAEEVAKQIEEYGGQAITFGGDV 135

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349
           +       ++   + + G IDVV+NNA +  D++ I      + + I +N+T +   T  
Sbjct: 136 SKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQA 195

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A++IM K    K G +IN+SSV  L  +     Y A K  V+ FS    R        V 
Sbjct: 196 AVKIMMKK---KRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGASRNINVN 252

Query: 530 VLTVCFGATD-TALLTDE 580
           V+   F A+D TA L ++
Sbjct: 253 VVCPGFIASDMTAELGED 270


>UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80593 protein -
           Strongylocentrotus purpuratus
          Length = 258

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 7/186 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           + V ITG+A G+G  + +     G + + +LDI  E  K L  EL SK G     Y  D+
Sbjct: 63  RTVLITGSANGLGRLLAQEFARRGAQ-LVLLDIDIEGNKLLAEELCSK-GRSAHAYYCDL 120

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349
           + +     ++  + ++ G +D++INNAA ++       S    +K  EVN  A I  T  
Sbjct: 121 SRKTDLYSVIAQIKRDIGHVDILINNAATLSGKPVLQCSDSAIEKVFEVNTMAYIWLTKA 180

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVG-RPEHFSKTGV 526
            +  M      K G V+N++S+A     + +  Y A+KSA++ F+  +G   +    TGV
Sbjct: 181 LLPDMLNR---KQGHVVNIASLAGFVGVNGLADYCASKSAIIGFTEALGYELKQMKATGV 237

Query: 527 RVLTVC 544
            +  VC
Sbjct: 238 HLSLVC 243


>UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Novosphingobium aromaticivorans (strain DSM 12444)
          Length = 266

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 56/191 (29%), Positives = 90/191 (47%), Gaps = 4/191 (2%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           ++   +TGAA GIGE + R    EG   + + D  +E G ++  +L    G + +F R D
Sbjct: 8   NRAAVVTGAADGIGEGIARRFAAEGAA-VVVADYDDERGPAVARDLRG-LGARAEFIRCD 65

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKAI 355
           V+  E  +G ++  V+  G +D+++NNA      + I KK  E    AL   + +T  A+
Sbjct: 66  VSRREDVIGAVDLCVERFGSVDILVNNAYRGEGPVRIEKKTDERFDEALRMCLFATKWAM 125

Query: 356 EIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           E    H   KG G VIN++S+  +        Y   K AV  +S    R   ++  G+ V
Sbjct: 126 ERALPHMKAKGWGRVINMASLNGVNAHMGSADYNVAKEAVRAYSRTAAR--EWAPYGICV 183

Query: 533 LTVCFGATDTA 565
             +C  A   A
Sbjct: 184 NVICPAAVSAA 194


>UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=4; Shewanella|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Shewanella sp.
           (strain ANA-3)
          Length = 292

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 53/200 (26%), Positives = 97/200 (48%), Gaps = 7/200 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEA-GKSLQVELNSKYGNKTKFYR 178
           K KV  ITG+ +GIG +   +L ++G  H+ +  +  EA G+ L  E   +Y   T F  
Sbjct: 35  KGKVGLITGSTSGIGLATAHVLAEQGC-HLILHGLMPEAEGRRLAAEFAEQYHIHTYFSN 93

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 340
           +D+ + E     ++A V+  G ID+++NNA + +        I  +   I +N+++   +
Sbjct: 94  ADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFHT 153

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
             +A+  M +    + G +IN++SV  L  S     Y A K  ++  +  V      ++ 
Sbjct: 154 IQQAVPAMAEK---RWGRIINIASVHGLVASVNKAAYCAAKHGIVGLTKVVA--IECAEQ 208

Query: 521 GVRVLTVCFGATDTALLTDE 580
           G+ V  +C G  DT L+  +
Sbjct: 209 GITVNAICPGWVDTPLINKQ 228


>UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2;
           Streptomyces|Rep: Putative dehydrogenase - Streptomyces
           avermitilis
          Length = 584

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 54/194 (27%), Positives = 97/194 (50%), Gaps = 9/194 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 184
           ++V +TGA +GIG +      + G + +A+   AE A ++   E++   G    +  + D
Sbjct: 317 QLVLVTGAGSGIGRATAYAFAEAGARVVAVDRNAEGAART--AEMSRLIGAPDAWAETVD 374

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 346
           V++E+    +   V  E G +DV++NNA +       + +   ++K ++VN+  +I    
Sbjct: 375 VSDEQAMEKLAEKVATEYGVVDVLVNNAGIGLSGSFFDTTAEDWRKVLDVNLWGVI---- 430

Query: 347 KAIEIMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               + GK     G+GG ++N +S AA   S  +P Y  +K+AVL  S C+ R E  +  
Sbjct: 431 HGCRLFGKQMAERGQGGHIVNTASAAAYQPSKALPAYSTSKAAVLMLSECL-RAE-LAGQ 488

Query: 521 GVRVLTVCFGATDT 562
           G+ V  +C G   T
Sbjct: 489 GIGVSAICPGFVHT 502


>UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Chromobacterium violaceum
          Length = 246

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 55/196 (28%), Positives = 95/196 (48%), Gaps = 6/196 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K KV  ITG+A+GIG++     + EG   +A+ D+  +A K++  EL +  G +   Y+ 
Sbjct: 4   KGKVSIITGSASGIGKATAEKFVKEGAI-VAVCDLNPDAVKTVVDELKA-LGGEAYGYKV 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 343
           DVT++     ++  +    G IDV++NNA ++ D+  I      + K I++N+  +    
Sbjct: 62  DVTDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQFDKVIDINLKGVYNCA 121

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              ++ M +     GG ++N SSV  +  +     Y A K  V+ F     +     K G
Sbjct: 122 RAVVDTMVEQG---GGVILNASSVVGVYGNFGQTNYAAAKFGVIGFVKTWAK--ELGKKG 176

Query: 524 VRVLTVCFGATDTALL 571
           +R   VC G   T +L
Sbjct: 177 IRANAVCPGFVATPIL 192


>UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii
           KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain
           KSM-K16)
          Length = 257

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 53/189 (28%), Positives = 101/189 (53%), Gaps = 8/189 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K   +TG A G+G ++ + L   G   IAI+DI  EA      E+ + Y   T+  ++DV
Sbjct: 12  KHAVVTGGAQGLGFTIAKSLAAFGCD-IAIVDIDAEAAAKAAQEITTTYSVNTQSIQADV 70

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIGI----YKKAIEVNVTALITSTLK 349
           + EE    +++ V++    IDV++NNA ++   D++ +    +K+ ++VN+ AL  ++ +
Sbjct: 71  SKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQ 130

Query: 350 AIEIMGKHSGGKG-GTVINVSSVAA-LTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
               +GKH    G G+++N+SS++A +        Y A+K AV   +  +     +++ G
Sbjct: 131 ----VGKHMVANGSGSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSLA--SEWAQYG 184

Query: 524 VRVLTVCFG 550
           +RV  +  G
Sbjct: 185 IRVNAIAPG 193


>UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC
           16129)
          Length = 256

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 58/200 (29%), Positives = 94/200 (47%), Gaps = 10/200 (5%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +D+V  ITGAA+G G +  ++   EG K +A  DI +E G    VE   + G +    + 
Sbjct: 4   EDRVAVITGAASGQGRAAAKLFASEGAKVVAA-DI-DEGGAQRTVEEIKEAGGEATAVKV 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV-----TALITSTL 346
           DV+ E     ++ +     G +DV+ NNA +   + G  K A  V        A++   L
Sbjct: 62  DVSREPDVRAMVESATDRYGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAILAINL 121

Query: 347 KAIEIMGKHS----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHF 511
           K + +  KH+      +G G++IN +S+ AL        Y A K  V+ FS  +     +
Sbjct: 122 KGVALGCKHAIPVMERQGYGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLA--VEW 179

Query: 512 SKTGVRVLTVCFGATDTALL 571
              G+RV  +C G  DT ++
Sbjct: 180 GPRGIRVNCICPGGVDTPMI 199


>UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Mesorhizobium sp. BNC1|Rep: Short-chain
           dehydrogenase/reductase SDR - Mesorhizobium sp. (strain
           BNC1)
          Length = 257

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 55/192 (28%), Positives = 94/192 (48%), Gaps = 5/192 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 184
           KV  +TGAA G+GE++   L  +G + +A+LD+ +E G  +   +    GN   +YR+ D
Sbjct: 7   KVALVTGAARGLGEAIAVELAAQGAR-VALLDVLDELGAEVAENIKKSSGN--AYYRNCD 63

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTALITSTLKAI- 355
           + + E     ++ V    G +DV++NNAA+      I + + E   N+  +  S++    
Sbjct: 64  IRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRFC 123

Query: 356 -EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
             ++ +     GG VIN+SSV           Y ATK A++  S  +     + +  +RV
Sbjct: 124 RFVLPRMQEAGGGAVINMSSVHQSHSLTGWTAYAATKGAIISMSRQLA--AEWGRFNIRV 181

Query: 533 LTVCFGATDTAL 568
            TV  GA D  +
Sbjct: 182 NTVSPGAIDATM 193


>UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=19; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 246

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 55/193 (28%), Positives = 92/193 (47%), Gaps = 6/193 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K+  +TGA  GIG+++   L  EG   + + D+  +A K     L+    +      +DV
Sbjct: 7   KIAVVTGAGQGIGKAIATKLAAEGAT-VVVTDVDHQAAKETAAALD----HGAIGLHADV 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLK 349
           T+      +++ VV   G IDV++NNA      A ++     + + I +N+  ++ ++ K
Sbjct: 62  TDRTSVDAMVDEVVATFGRIDVLVNNAGWDKGEAFVDSEPETWDRIIGINLYGVLNTSKK 121

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            + IM        G+V+N+ S A    S    +Y A K  V+ FS    R    +++ V 
Sbjct: 122 VLPIMAAQG---SGSVVNIGSDAGRVGSSGEAVYSAAKGGVIAFSKATAR--EMARSQVN 176

Query: 530 VLTVCFGATDTAL 568
           V  VC G TDTAL
Sbjct: 177 VNCVCPGPTDTAL 189


>UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Comamonas testosteroni
           KF-1
          Length = 259

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +   ITGA  GIG +   +   EG   + +   AE   ++ +  L +  G +     +DV
Sbjct: 9   RTALITGAGAGIGAAASHLFCKEGAAVLMVDANAEALERTREAILQAVPGARLACVMADV 68

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITSTLK 349
           ++E      +   VQ+ GG+D ++NNAA+ N S      A E      VN+  +      
Sbjct: 69  SDESAAAAAVGQCVQQWGGLDTLVNNAAMRNYSAAADATAAEWQAMVGVNLVGMSNYCRA 128

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A+  + + SG   G+++NVSS  A+T    M +Y ATK+A L ++  +   E  +  GVR
Sbjct: 129 ALPAL-RQSG--TGSIVNVSSCYAVTGRKGMALYDATKAAQLAYTRSLAFEE--AAHGVR 183

Query: 530 VLTVCFGATDT 562
              VC G+T T
Sbjct: 184 ANAVCPGSTLT 194


>UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 284

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 67/220 (30%), Positives = 100/220 (45%), Gaps = 19/220 (8%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTKFYR 178
           DKV  ITG++ GIG++  R+L  EG K       AE  E  K++ +      GN      
Sbjct: 6   DKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGN-VLVVV 64

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTA 328
            D+T E     ++ + + + G ID+++NNA            +N SI  Y K  E+NV +
Sbjct: 65  GDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQS 124

Query: 329 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCVGRPE 505
           +I  T KA      H     G ++N+SS+ A   + V  P Y   K+A+ Q++       
Sbjct: 125 VIEMTQKA----RPHLAKTQGEIVNISSIGAGPAAQVASPYYSIAKAALDQYTRTAA--I 178

Query: 506 HFSKTGVRVLTVCFGATDTAL------LTDEKLGTFDKYL 607
                G+RV +V  GA  T        LT+EK   F  YL
Sbjct: 179 DLVPEGIRVNSVSPGAVSTGFSAVSRGLTEEKSKAFYDYL 218


>UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;
           n=11; cellular organisms|Rep: Uncharacterized
           oxidoreductase TM_0019 - Thermotoga maritima
          Length = 256

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 52/192 (27%), Positives = 96/192 (50%), Gaps = 6/192 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG   GIG ++ ++  + G+K + I +I EEAG   +  L  + G    F ++DV
Sbjct: 5   KVAVVTGGGQGIGAAIAQLFAENGMK-VVIAEIDEEAGVEREEMLRER-GLDVTFVKTDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349
            +E     ++   V+  GG+DV++NNAA+M+        +  +++ I VN+T     +  
Sbjct: 63  ADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
             E M K     GG +IN++S  A         Y A+K  ++  ++ +      S+  +R
Sbjct: 123 CAEEMIKRG---GGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLA--VSLSRYHIR 177

Query: 530 VLTVCFGATDTA 565
           V+++  G  +T+
Sbjct: 178 VVSISPGWIETS 189


>UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family member
           11 precursor; n=7; Eukaryota|Rep:
           Dehydrogenase/reductase SDR family member 11 precursor -
           Gallus gallus (Chicken)
          Length = 255

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 54/193 (27%), Positives = 94/193 (48%), Gaps = 8/193 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +V  +TGA+ GIG +V R L+  G+K +      ++  K      ++ Y      Y+ D+
Sbjct: 7   RVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLIPYKCDL 66

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 349
           +NEE  L + +A+     G+DV INNA       L++     ++  I+VNV A+   T +
Sbjct: 67  SNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAVSICTRE 126

Query: 350 AIEIMGKHSGGKGGTVINVSSV--AALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
           A + M K      G +IN++S+   ++    V+  Y ATK AV   +  + +    +KT 
Sbjct: 127 AYQSM-KERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELREAKTH 185

Query: 524 VRVLTVCFGATDT 562
           +R   +  G  +T
Sbjct: 186 IRATCISPGLVET 198


>UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2;
           Proteobacteria|Rep: 2O-beta-hydroxysteroid dehydrogenase
           - Pseudoalteromonas haloplanktis (strain TAC 125)
          Length = 262

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 55/202 (27%), Positives = 99/202 (49%), Gaps = 6/202 (2%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +KV  +TGAA GIG ++ + L+D G   IA   + EE  +  Q     + G+K      D
Sbjct: 9   NKVALVTGAARGIGRAICQALVDSGATVIATDILTEELNQMAQ-----ELGDKVTPMTHD 63

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 346
           VT+E  +  I++A +++   ID+++NNA ++            ++K I++N+T       
Sbjct: 64  VTDELQWQSIVSATLEKHQKIDILVNNAGILLFATLETTEPQQFRKLIDINITGTFLGLH 123

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             I  M K +G   G ++N+SS +++  ++    Y A+K AV   +            G+
Sbjct: 124 SVIPCM-KKAG--SGAIVNISSASSILPNNGTGAYAASKYAVRGLTRTAAL--ELGPFGI 178

Query: 527 RVLTVCFGATDTALLTDEKLGT 592
           RV +V  GA +T +   + L +
Sbjct: 179 RVNSVHPGAVNTPMTNPQGLSS 200


>UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 250

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 47/169 (27%), Positives = 89/169 (52%), Gaps = 7/169 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGAA GIG ++    + EG K + I DI +  G+ +  EL    G +  F+ +DV
Sbjct: 10  KVAIVTGAANGIGVAIATRFVTEGAK-VVIADI-DAGGQGVAAEL----GERATFFSTDV 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITSTL 346
           ++      +++  ++  GG+ V+ NNA +       ++D +  +++ + V++  ++  + 
Sbjct: 64  SDPVQTQALVDFTIRHFGGLHVLCNNAGVSGGLRRFLDDDLRDFERVVAVDLYGVMACSR 123

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCV 493
            A   M  H GG    ++N++S A +T    M  Y A K+ V+QF+ C+
Sbjct: 124 SAARHMVDHGGG---AIVNIASGAGITPGIGMLPYRAAKAGVVQFTRCL 169


>UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Acidobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Acidobacteria bacterium
           (strain Ellin345)
          Length = 257

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 59/210 (28%), Positives = 100/210 (47%), Gaps = 3/210 (1%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  + G  TGIG ++   L D G   ++     E+   +   E+  + G +T    SDV
Sbjct: 10  KVAVVVGGTTGIGRAISFGLADAGADVVSTARREEQVNAAAD-EIERR-GRQTLRVCSDV 67

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAIEI 361
           T+      + NAV+ +   +D+++N A     +  +     E N  +   +T  L+A ++
Sbjct: 68  TSRASIQSLCNAVLAKFQKVDILVNCAGTTKRTPTLTVSEDEWNKILDTNLTGALRACQV 127

Query: 362 MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
            GKH   +G G +IN++S+++    H +  Y A+K+A+L  +  +     +SK GV V  
Sbjct: 128 FGKHMIERGYGRIINIASLSSFVALHEVAAYSASKAALLSLTRSLA--VEWSKKGVTVNA 185

Query: 539 VCFGATDTALLTDEKLGTFDKYLEFFMLGP 628
           +  G   TAL T E L    +  EF M  P
Sbjct: 186 IAPGVFRTALNT-ELLDNTPRGQEFLMRTP 214


>UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivorax
           borkumensis SK2|Rep: Oxidoreductase, putative -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 581

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 56/194 (28%), Positives = 97/194 (50%), Gaps = 7/194 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K V ITGA +GIG          G   +   DI  E   +    + ++ G +    + DV
Sbjct: 315 KRVIITGAGSGIGRETALAFARRGAL-VVCTDINSEEAAATARTITAE-GGEALSRKCDV 372

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALIT-STL 346
           +N      +   V +E G  D+V+NNA      +L++ S+  +++ + VN+  +I  S L
Sbjct: 373 SNTRSMEALATWVEKELGAPDIVVNNAGIGLSGSLLDTSVKDWQQVLGVNLWGVIHGSRL 432

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
            A +++ +   G+ G ++N++S AA   S ++P Y  +KSAVL FS C+ R E   +  +
Sbjct: 433 FARQMIDQ---GRAGHIVNIASAAAFMPSRMLPAYATSKSAVLMFSECL-RAE-MDEHNI 487

Query: 527 RVLTVCFGATDTAL 568
            V  +C G  +T +
Sbjct: 488 GVSAICPGIINTPI 501


>UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family; n=1; Photobacterium
           profundum|Rep: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family - Photobacterium
           profundum (Photobacterium sp. (strain SS9))
          Length = 255

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 54/194 (27%), Positives = 89/194 (45%), Gaps = 7/194 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  I+G  +GIGE+  R+   +G   + ++   E  G+ L  ELN++Y   T F ++D+
Sbjct: 10  KVALISGITSGIGEATARLFSQQGAS-LVLVARNENKGQMLAEELNAQY--PTLFIKADI 66

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346
           T       +    + E GGID   NNA        +   S  I+ + I  N+        
Sbjct: 67  TQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLN 126

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
           + + IM K      GT++N++S+ ++        Y  ++ AVL  +        ++K GV
Sbjct: 127 RQLSIMSKQG---HGTIVNMASICSVLARPNRAAYNTSRHAVLGLTRSAA--VEYAKQGV 181

Query: 527 RVLTVCFGATDTAL 568
           RV  V  GA DT +
Sbjct: 182 RVNAVAPGAIDTPI 195


>UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain
           dehydrogenase/reductase SDR - Rhodopseudomonas palustris
           (strain BisB5)
          Length = 263

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 52/195 (26%), Positives = 89/195 (45%), Gaps = 7/195 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +VV +TG A+GIG +       +G   + + DI +  G    VE   + G++ ++ R+DV
Sbjct: 21  RVVLVTGGASGIGRAAALAWARQGCS-VLVADIDDRGGAET-VEAIERLGSRARYQRNDV 78

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346
           T+E     ++   V   G +DV  NNA +   S  I       ++  I VN+  +  S  
Sbjct: 79  TDERECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGADWRHVINVNLLGIFNSMQ 138

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             + +    S G  G ++N +SV  L        Y A K  V+  + C      + ++G+
Sbjct: 139 PQLRLF--ESQG-AGVIVNTASVIGLRGVAGGSAYAAAKHGVIGLTKCAAL--EYGRSGI 193

Query: 527 RVLTVCFGATDTALL 571
           R+  VC G  +T L+
Sbjct: 194 RINAVCPGYIETPLV 208


>UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Acidobacteria bacterium (strain Ellin345)
          Length = 271

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 55/192 (28%), Positives = 90/192 (46%), Gaps = 4/192 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG A GIGE+  R +   G   +AILD  E+AG      + + +G + KF+R DV
Sbjct: 8   KVAVVTGGAMGIGEACARKIALAGAS-VAILDPNEDAGTKTAAAIRA-HGGECKFFRCDV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367
           +  +     +  V+ +   ID++++NA +     G      E +   +I   LK   ++ 
Sbjct: 66  SKSKDVEQAVGDVITKHSQIDILVSNAGI--QYYGDVITTPEDDWDRVIGVNLKGCFLIS 123

Query: 368 K----HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
           K    H    GG ++ + SV + T       Y  +K AVL  +  +     ++  G+RV 
Sbjct: 124 KFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMAL--DYAHKGIRVN 181

Query: 536 TVCFGATDTALL 571
            VC G  DT +L
Sbjct: 182 CVCPGTIDTPML 193


>UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=16; Pseudomonas|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Pseudomonas aeruginosa PA7
          Length = 266

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 55/197 (27%), Positives = 97/197 (49%), Gaps = 7/197 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +   ITGA++GIG ++   L   G + + ++    +A +S+  EL  ++G +  F   D+
Sbjct: 3   RYALITGASSGIGLALAEALARRG-RALILVARQRDALESIAYELAQRFGVEVLFRTCDL 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 349
                  G+L+ + Q +  ID+++NNA +      ++      ++ IE+N+ AL     +
Sbjct: 62  AEPLQLSGLLHELEQGERQIDLLVNNAGIGSAGPFVDQEWAREQELIELNILALA----R 117

Query: 350 AIEIMGKHSGGKGG-TVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
               +G     +GG  ++NV+SVAA      M  Y+A+K+ VL FS   G  E      V
Sbjct: 118 LCHALGTRMAAQGGGQILNVASVAAFQPGAWMSNYYASKAYVLHFSE--GLREELKARAV 175

Query: 527 RVLTVCFGATDTALLTD 577
           +V  +C G T TA   +
Sbjct: 176 KVSVLCPGPTRTAFFRE 192


>UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1;
           Flavobacteriales bacterium HTCC2170|Rep: Probable
           glucose 1-dehydrogenase - Flavobacteriales bacterium
           HTCC2170
          Length = 268

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 53/198 (26%), Positives = 93/198 (46%), Gaps = 5/198 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K K V +TG + GIG  + R L   G +     +  E++ + L  E+++ YG +T    +
Sbjct: 7   KGKRVLVTGGSRGIGAEICRKLAACGAEVFINYNSNEQSAQDLANEISNSYGVRTGIACA 66

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           DV+  E    +   +    GGID+++NNA    +SI      +E     +I   LK   +
Sbjct: 67  DVSKAEQVKQMFLKMDGVMGGIDILVNNAG--TESIHHVLDLVEEEWDRVINVNLKGPFL 124

Query: 362 MGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             K +G +     GG +IN+SS+  +     +  Y + K+ +   S C+      ++  +
Sbjct: 125 CSKEAGDRMEKNGGGVIINISSIHDVVPRKGLIHYCSAKAGLKMLSKCLSL--ELAENNI 182

Query: 527 RVLTVCFGATDTALLTDE 580
           RV++V  GA  T +  DE
Sbjct: 183 RVVSVAPGAISTEMNRDE 200


>UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;
           Bacteria|Rep: Short-chain alcohol dehydrogenase -
           Burkholderia dolosa AUO158
          Length = 284

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 57/195 (29%), Positives = 100/195 (51%), Gaps = 7/195 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +KVV ITGA++GIGE+  ++L  +G   +A+     +  + +  E+ +K G +   ++ D
Sbjct: 44  NKVVVITGASSGIGEATAKLLASKGAT-VALAARRLDKLQRVAAEIVAK-GGQVSVHQVD 101

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS-IGIYK-----KAIEVNVTALITSTL 346
           VT++E    ++N VV + G +DV++NNA LM  + + + K     + I++N+  L+    
Sbjct: 102 VTDQEQVNRLINDVVSQHGRLDVMVNNAGLMAIAPLSLRKTDEWDRMIDINIKGLLYGVA 161

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAAL-TQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
            A+ +  K    + G  +N++SV  L   S    +Y  TK AV   S  +    H     
Sbjct: 162 AALPVFEKQ---QSGHFVNIASVVGLKVFSPGGTVYSGTKFAVRAISEGL---RHEVGGN 215

Query: 524 VRVLTVCFGATDTAL 568
           +R   +  GA DT L
Sbjct: 216 IRTTVISPGAIDTEL 230


>UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1;
           marine gamma proteobacterium HTCC2143|Rep: Short-chain
           dehydrogenase/reductase - marine gamma proteobacterium
           HTCC2143
          Length = 264

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 57/193 (29%), Positives = 98/193 (50%), Gaps = 6/193 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITG  +GIGE+   I + EG   + +   +EE G+++     ++ G+K  + ++DV
Sbjct: 8   KVAIITGGTSGIGEATADIYIKEGAT-VVLTGRSEEKGQAIA----NRLGDKAHYIKADV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA----ALMNDSI--GIYKKAIEVNVTALITSTLK 349
           + EE     ++  V+  G +DV+ NNA        DSI  G     +++ +++++     
Sbjct: 63  SKEEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSSVVLGIRY 122

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           AIE M K +G  GG +IN +S+AA+       +Y A K+AV  ++   G        G+R
Sbjct: 123 AIEPM-KANG--GGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAG--VELGPLGIR 177

Query: 530 VLTVCFGATDTAL 568
           V  +  GA  T +
Sbjct: 178 VNCISPGAIATPI 190


>UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 292

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 54/197 (27%), Positives = 93/197 (47%), Gaps = 6/197 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV F+TG A+GIG  +V   + EG K +AI+D+ +    +   ELN ++   T     DV
Sbjct: 36  KVCFVTGGASGIGLGIVERFVKEGGK-VAIVDLDKTKADNASKELNQRFPGSTISVECDV 94

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349
           +NEE     +   V+  GG+DV+++NA L +        +  ++K + V++      T  
Sbjct: 95  SNEEQVSKGIKDTVERFGGLDVIVSNAGLQHIETLETVELATWRKMMAVHLDGAFLCTKY 154

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A++   K    +GGT++ + SV +   S     Y   K  +     C G     +K  +R
Sbjct: 155 AMQEF-KKDIKRGGTILYMGSVHSKYASEYKIPYVTAKHGLEGL--CRGVAREGAKHNIR 211

Query: 530 VLTVCFGATDTALLTDE 580
              +C G   T L+ ++
Sbjct: 212 ANLICPGFVLTPLVKNQ 228


>UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 240

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 45/152 (29%), Positives = 78/152 (51%), Gaps = 4/152 (2%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQ---VELNSKYGN-KTKF 172
           +KV  +T    GIG S   + L    +++A+LD+ +     +      L  ++G  K  +
Sbjct: 5   NKVAIVTDGLGGIGFSTYLLRLK--AQYVAVLDLPQNNSPHVVDGLKTLEEEFGKGKFGY 62

Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 352
           Y  +V N E F  +   VV+ +G +D+++ NAA+  D+       I+VN+  +I  TL A
Sbjct: 63  YHVNVANAESFAAVYAKVVEHKGYVDILVYNAAVAKDTE--IDLTIDVNLKGVIKGTLHA 120

Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPI 448
           +E MG H   KGG V+N++S   L  +  + +
Sbjct: 121 VEQMGVHKNQKGGVVVNIASFLGLEHNKFLGV 152


>UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2;
           Bacillaceae|Rep: 2O-beta-hydroxysteroid dehydrogenase -
           Oceanobacillus iheyensis
          Length = 244

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 63/217 (29%), Positives = 107/217 (49%), Gaps = 6/217 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           ++KV  ITG A G+G S VR+   EG K +   D+ EE G +L  EL    G   KF + 
Sbjct: 5   ENKVAIITGGARGMGASHVRLFAKEGAK-VVFTDLNEEGGLALANEL----GENVKFVKQ 59

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 343
           DVTN + +  +++   +  G ++V++NNA       LM  +   Y+K I++N  ++    
Sbjct: 60  DVTNADDWETVISETEEAFGPVNVLVNNAGISLSIPLMEMTEEQYRKIIDINQVSVFLG- 118

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
           +KA+    + +G   G+++N+SS+  +    V   Y  +K AV   +            G
Sbjct: 119 MKAVVPSMQKAG--SGSIVNISSMNGIVAGAVG--YTDSKFAVRGATKAAA--VQLGGLG 172

Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLEFFMLGPTK 634
           +RV +V  G  +T ++T  K    ++  EF    P+K
Sbjct: 173 IRVNSVHPGVIETPMVT--KGDAVEQIKEFAKQIPSK 207


>UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus
           thuringiensis
          Length = 247

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 50/196 (25%), Positives = 98/196 (50%), Gaps = 6/196 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG A GIG+++   L  EG K +   + ++EA ++L  EL  K G+     ++DV
Sbjct: 7   KVAIVTGGAKGIGKAITVALAQEGAKVVINYNSSKEAAENLVNEL-GKEGHDVYAVQADV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349
           +  E    ++   V   G +D+++NNA +  D      +   +++ I+VN++++  +T  
Sbjct: 66  SKVEDANRLVEEAVNHFGKVDILVNNAGITRDRTFKKLNREDWERVIDVNLSSVFNTTSA 125

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            +  +   +  + G +I++SS+           Y A K+ +L F+  +      +KT V 
Sbjct: 126 VLPYI---TEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLAL--ELAKTNVT 180

Query: 530 VLTVCFGATDTALLTD 577
           V  +C G  DT ++ +
Sbjct: 181 VNAICPGFIDTEMVAE 196


>UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Polaromonas sp.
           (strain JS666 / ATCC BAA-500)
          Length = 249

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 63/213 (29%), Positives = 98/213 (46%), Gaps = 6/213 (2%)
 Frame = +2

Query: 14  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193
           V +TGA TGIG +       +G  ++ +    EEAG+SL  EL +  G K +F ++DV N
Sbjct: 6   VLVTGALTGIGRATAIAFAKQGA-NVVVSGRREEAGQSLAAELRT-LGAKAEFIKADVAN 63

Query: 194 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 373
           E     ++   V   G +D+ INNA     ++G   +    NV A  ++ +    +  KH
Sbjct: 64  EAEVRSLVEKAVSLFGQLDIAINNAG-TEGALGPITEQSTENVHATFSTNVLGTLLSMKH 122

Query: 374 S----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538
                  +G G+++N+SS+A         +Y A+K AV   +         +  GVRV  
Sbjct: 123 EIRAMQAQGHGSIVNLSSIAGKVGMAGASVYVASKHAVEGLTKSAAL--EGAAFGVRVNA 180

Query: 539 VCFGATDTALLTDEKLGTFDKYLEFFMLG-PTK 634
           V  G   T +L D  +G  +     FM G P K
Sbjct: 181 VAPGPVQTDML-DRFVGRDESVKAGFMAGVPAK 212


>UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1;
           Bacillus sp. SG-1|Rep: Putative uncharacterized protein
           - Bacillus sp. SG-1
          Length = 260

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 61/202 (30%), Positives = 95/202 (47%), Gaps = 7/202 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K+KVV ITGA++G+G    +         + +   +E+   +L  EL  K+G K      
Sbjct: 2   KNKVVVITGASSGLGVEFAKQFAGRSYD-LVLTARSEDKLNNLAKELEGKHGIKAHVIPI 60

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGIYKKA--IEVNVTALITST 343
           D++       +   VV      +++INNA        +   I K+   IEVN+TAL   T
Sbjct: 61  DLSQHGSAKTLHEKVVSLGLTTEILINNAGFGLFGEFEDTDIQKEVDMIEVNITALTELT 120

Query: 344 LKAIEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               +  GK    G  G ++NV+SVAA     +M +Y+ATK+ VL  S  +     +   
Sbjct: 121 ----KYFGKEMVVGNTGKILNVASVAAFQPGPLMAVYYATKAYVLSLSEALS--NEWKDK 174

Query: 521 GVRVLTVCFGATDTALLTDEKL 586
           GV+V  +C GAT+T      +L
Sbjct: 175 GVKVSVLCPGATETGFSNSAEL 196


>UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like
           protein; n=1; Reinekea sp. MED297|Rep: Short-chain
           alcohol dehydrogenase-like protein - Reinekea sp. MED297
          Length = 672

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 51/169 (30%), Positives = 90/169 (53%), Gaps = 8/169 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KVV ITG ++GIG++    L   G   I     AE+  ++  +++ S  G     +++D+
Sbjct: 385 KVVLITGGSSGIGKATAMRLSKAGATVIICARDAEKLRRA-HLDIESTGGTVVS-HQADI 442

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA------ALMN--DSIGIYKKAIEVNVTALITST 343
           T  +    +   + +E  G+D++INNA      ++M   D +  +++ IE+N  A +  T
Sbjct: 443 TQPDDVDRLFGMIEREFAGLDILINNAGHSIRRSVMQSLDRLHDFQRTIELNYLASVAIT 502

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC 490
           LKA+ +M +    + G VIN+SS+  L+ S     Y A+K+A+  FS C
Sbjct: 503 LKALPMMDRR---REGHVINISSIGVLSNSPRFSAYVASKAALEAFSRC 548


>UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Short-chain dehydrogenase/reductase SDR - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 253

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 49/173 (28%), Positives = 95/173 (54%), Gaps = 10/173 (5%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           DKV  +TGA++ IG+ + +  ++EG K I I    E   ++ + E+ ++  + T     D
Sbjct: 5   DKVAIVTGASSDIGKGIAKKFVEEGAKVILIARNLEGL-ENTRKEIGNE--DSTAAMTCD 61

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITST 343
           + +E   L ++N ++   G ID+++NNA  +ND I  +       +K I VN+  +   T
Sbjct: 62  LVDESQTLQVVNQIMDTYGKIDILVNNAGAINDPIHFHEMQNSEIQKLINVNLLGVFNMT 121

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVA---ALTQSHVMPIYFATKSAVLQFSNCV 493
            KA  ++ K +  K G+++N+ S++   A+ + H + +Y ATK+A+  F+  +
Sbjct: 122 -KA--VLTKMADVKSGSIVNIGSISSERAIPRVH-LAVYSATKAAIPMFTKSI 170


>UniRef50_Q13H99 Cluster: Putative short-chain
           dehydrogenase/reductase; n=3; Proteobacteria|Rep:
           Putative short-chain dehydrogenase/reductase -
           Burkholderia xenovorans (strain LB400)
          Length = 274

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 60/223 (26%), Positives = 107/223 (47%), Gaps = 14/223 (6%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           ++KV  +TGA  G+G +  R L   G + +A++DI  EA  ++  ++    G +    R+
Sbjct: 11  ENKVAIVTGAGAGLGAACARALAQHGAR-VAVVDINGEAAAAVAADI----GERAMSVRT 65

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND------------SIGIYKKAIEVNVT 325
           DV++E     +++AV++  G ID++ NNAA+++D            S+ ++ +A+ VN+ 
Sbjct: 66  DVSSEAQVKAMVSAVLEHFGRIDILHNNAAVLDDAQRAGDRDVINMSVEVWDRAMAVNLR 125

Query: 326 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPE 505
             +     AI  M +   G GG++I+ SS         M  Y A+K+ +   S  V    
Sbjct: 126 GAMLCCKHAIPAMLR---GGGGSIIHSSSGFGAQGDFTMSAYAASKAGLAMLSKSVA--A 180

Query: 506 HFSKTGVRVLTVCFG--ATDTALLTDEKLGTFDKYLEFFMLGP 628
            + K  +R  T+  G    D  L  D K    D +L  ++  P
Sbjct: 181 QYGKERIRSNTIQIGLVVADHPLPEDIKGVILDGHLTPYLGDP 223


>UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Xanthobacter autotrophicus Py2|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Xanthobacter sp. (strain Py2)
          Length = 261

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 8/201 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDK + ITGAA GIG ++ + L  +G + I + D++E A +++  E+ +  G        
Sbjct: 5   KDKSIVITGAAGGIGAAIAKALAADGAR-ITVADLSEPAARAVAGEITAA-GGTAIAVAV 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 343
           DV        +L+  V   G +DV+ NNA +      ++ +   ++   +VN   ++   
Sbjct: 63  DVRQRAQVRALLDEAVAAHGRLDVLFNNAGVAQTRPFLDITEDDWRFVTDVNALGVLIGM 122

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
            +AI+   K  GG GG ++N +S+AA      +  Y A+K AV+  +    R   F K  
Sbjct: 123 QEAIKTF-KRQGG-GGKIVNTASIAAKQGYEPLAHYCASKFAVVALTQAAARA--FGKDQ 178

Query: 524 VRVLTVCFG--ATDTALLTDE 580
           + V   C G  ATD   + D+
Sbjct: 179 ITVNAFCPGVVATDMWKIIDK 199


>UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1;
           Dorea longicatena DSM 13814|Rep: Putative
           uncharacterized protein - Dorea longicatena DSM 13814
          Length = 244

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 56/221 (25%), Positives = 101/221 (45%), Gaps = 9/221 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           + K +FITGA+ GIG+S+  +    G         + +  K L+  +  KY         
Sbjct: 2   EQKTIFITGASRGIGKSIALLFASRGYHTFLNCSSSVDELKKLRAYITEKYHTPCTLVPG 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDSIG-IYKKAIEVNVTALITST 343
           +V N +H   I N + QE   +DV++NNA      L+ D     + + I+ N++++    
Sbjct: 62  NVGNPDHVRAIYNKIYQECTHLDVLVNNAGISYINLLTDMTDEDWNRIIQTNLSSVFYCC 121

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
            +AI  M     GK   +IN+SS+   + +     Y A+KS +  F+  + +    + + 
Sbjct: 122 RQAIPPMVSKRSGK---IINISSMWGTSGASCEVAYSASKSGINGFTKALAK--ELAPSN 176

Query: 524 VRVLTVCFGATDTAL---LTDEKLGTFDKYLEFFMLGPTKE 637
           V+V  +  G  DT++   LT E+    ++ +     G  KE
Sbjct: 177 VQVNAIACGVIDTSMNDQLTSEERKALEEEIPAGRYGTPKE 217


>UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein]
           reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative
           3-oxoacyl-[acyl-carrier protein] reductase -
           Arthrobacter aurescens (strain TC1)
          Length = 261

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 6/194 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K V +TGA +G+G +V +  L EG   I + D++E++    + + NS    +     +DV
Sbjct: 9   KTVMVTGAGSGLGAAVFKRFLLEGANVIGV-DLSEDSMARFR-DRNSVLSGQITLKVADV 66

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 349
            + +    I+N  V+E G +DV++NNA +         S  +++  ++VNV  L  +T  
Sbjct: 67  GDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVDGLFYATRA 126

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A+     H     G ++N +SV+ +   +    Y A+K AV+ F+  V     +++ GVR
Sbjct: 127 AL----PHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVA--VDYAQRGVR 180

Query: 530 VLTVCFGATDTALL 571
              V  G   T LL
Sbjct: 181 CNAVAPGPVLTPLL 194


>UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Rep:
           Short chain dehydrogenase - Mycobacterium avium (strain
           104)
          Length = 594

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 54/193 (27%), Positives = 91/193 (47%), Gaps = 6/193 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           + ++  +TGA  GIG +    L  +G + + I+D  + A      +     G     Y+ 
Sbjct: 324 RGRLALVTGAGAGIGRATAVELARQGARKVVIVD-RDRAAADQTADAVRAAGAGAAVYQV 382

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           DV++E     +   V  E G +D+++NNA +     G + +    N  A++   ++ +  
Sbjct: 383 DVSDEAAMNDLAAQVRNEHGVVDILVNNAGI--GMAGRFLETSPANWDAIMGVNVRGVIW 440

Query: 362 MGKHSG------GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             +  G      G+GGT+INV+S AA   S  M  Y  TK+AVL  S  + R + F+  G
Sbjct: 441 GSRAFGAQMVERGQGGTIINVASAAAYLPSKSMVAYGTTKAAVLALSESL-RAD-FADEG 498

Query: 524 VRVLTVCFGATDT 562
           + V  VC G  +T
Sbjct: 499 ITVTAVCPGFVNT 511


>UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34;
           Proteobacteria|Rep: Acetoacetyl-CoA reductase -
           Acinetobacter sp. (strain RA3849)
          Length = 248

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 51/197 (25%), Positives = 91/197 (46%), Gaps = 6/197 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           + KV  +TGA  GIG  + R L+  G K IA +   EE  +   ++      +  +F  +
Sbjct: 3   EQKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLT 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 343
           D+ N E     +   +  +G +DV++NNA +  D      S   + + I+ N+  L T T
Sbjct: 63  DLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTVT 122

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
                +  K    K G ++N+SSV  L        Y A+K+ ++ F+  +   +  +++ 
Sbjct: 123 Q---PVFNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALA--QEGARSN 177

Query: 524 VRVLTVCFGATDTALLT 574
           + V  V  G T T ++T
Sbjct: 178 ICVNVVAPGYTATPMVT 194


>UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=8; root|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Pseudomonas paucimobilis (Sphingomonas paucimobilis)
          Length = 250

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 51/195 (26%), Positives = 94/195 (48%), Gaps = 7/195 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K + +TG  +GIG + V +L+  G  ++ + DI +EAG+++     +  G K  ++R D+
Sbjct: 7   KTIIVTGGGSGIGRATVELLVASGA-NVPVADINDEAGEAVV----ATSGGKAAYFRCDI 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346
             EE    ++   +   GG+D   NNAA       L   S+  +++++++NVT   T   
Sbjct: 62  AQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTG--TFLC 119

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
              +I+     G  G+++N +S A +    +   Y   K AV+  +        + K G+
Sbjct: 120 MKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAA--ADYGKHGI 177

Query: 527 RVLTVCFGATDTALL 571
           RV  +  GA  T +L
Sbjct: 178 RVNALVPGAVRTPML 192


>UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 254

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 60/197 (30%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KVV ITG A GIG++  ++LLD G K +A++DI E++    +  L+ +  ++      +V
Sbjct: 4   KVVLITGGAGGIGQATAKLLLDYGAK-VALVDINEDSLVKAKESLHVE-DDRVFTITGNV 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346
           T EE     +   V   G IDV  NNA +      I       ++K + +NVT +     
Sbjct: 62  TVEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLK 121

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             ++ M K      G+++N +S AA   S  M  Y A+K AV   +         +  G+
Sbjct: 122 HVMKQMKKQG---YGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAAL--EVASDGI 176

Query: 527 RVLTVCFGATDTALLTD 577
           RV  V   A DT +L D
Sbjct: 177 RVNAVAPAAIDTQMLAD 193


>UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=6; Desulfuromonadales|Rep: 3-oxoacyl-(Acyl
           carrier protein) reductase - Geobacter sulfurreducens
          Length = 246

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 57/215 (26%), Positives = 98/215 (45%), Gaps = 5/215 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KD +V +TG   GIG ++      +G    A     +EA ++L+ E     G+     R+
Sbjct: 4   KDSIVVVTGGTRGIGRAISLHFARQGALVTAAYRADDEAARALEAEAAGLPGS-IAVIRA 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           DV   E  + +++A   E G + V++NNA ++ D  G      E +  A++ + L  +  
Sbjct: 63  DVGTAEGAMAVIDAASGESGTLHVLVNNAGIIRD--GYLAMMAEDDWDAVMRANLSPLFH 120

Query: 362 -----MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
                + K    + G +IN+SSV+A   +     Y ATK A + F+  + R       G+
Sbjct: 121 CCKWGVRKMLARRRGAIINLSSVSAFAGTAGQTNYAATKGAAVSFTKSLAR--EVGPLGI 178

Query: 527 RVLTVCFGATDTALLTDEKLGTFDKYLEFFMLGPT 631
           RV  V  G  +T ++   K    D+ +   +LG T
Sbjct: 179 RVNAVAPGLIETEMIAGMKREMVDRIVGSSILGRT 213


>UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase, putative; n=26; Gammaproteobacteria|Rep:
           3-oxoacyl-(Acyl carrier protein) reductase, putative -
           Idiomarina loihiensis
          Length = 254

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 62/222 (27%), Positives = 98/222 (44%), Gaps = 15/222 (6%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KD V+ ITG A G+G ++      +G K +A++DI  +     Q +       K   Y  
Sbjct: 4   KDSVIVITGGAQGLGLAMAEDFARQGAK-LALIDINGDVLGEAQEQCEKLGAAKVVGYEV 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI---------------YKKAIEV 316
           D+T+EE    +   + QE  GIDV++NNA L+ D + I               ++  ++V
Sbjct: 63  DITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSVLDV 122

Query: 317 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVG 496
           N+T       +A   M K   GK G +IN+SSVA    +     Y ATK+ V+  +  V 
Sbjct: 123 NLTGTFLCGREAAAQMVK--AGKKGVIINISSVAR-AGNMGQTNYSATKAGVVAMT--VT 177

Query: 497 RPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLEFFML 622
                 + G+R   +  G  +T +    K    D+ L    L
Sbjct: 178 WARELGRYGIRCGAIAPGFIETPMTAQMKPEAVDRALSMVPL 219


>UniRef50_Q1Q261 Cluster: Strongly similar to
           3-oxoacyl-[acyl-carrier protein] reductase; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to 3-oxoacyl-[acyl-carrier protein] reductase -
           Candidatus Kuenenia stuttgartiensis
          Length = 239

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 53/210 (25%), Positives = 104/210 (49%), Gaps = 7/210 (3%)
 Frame = +2

Query: 14  VFITGAATGIGESVVRILLDEG----VKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           + +TG + GIG+++ ++ + EG    V H   +D  E+    L+ E +S  G+ +   ++
Sbjct: 1   MLVTGGSKGIGKAICKVFIGEGDHVIVNHCKPIDDIEK----LREEFSSPQGSFS-IEKA 55

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 355
           DVT+      +++ +V++ G IDV+INNA ++ D   +   A + N  +   +T      
Sbjct: 56  DVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYIMLMSAKDWNDVINVNLTGVFNCT 115

Query: 356 EIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           + + +H  G + GT+IN++S++ +T       Y A K  V+ F+  + +    +   +RV
Sbjct: 116 KAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAKGGVIAFTMALSK--ELAPFCIRV 173

Query: 533 LTVCFGATDTALLTDEKLGTFDKYLEFFML 622
            TV  G  +T ++        + Y E   L
Sbjct: 174 NTVAPGVIETDIIDSLDKNKRNSYKEHIPL 203


>UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Parvibaculum
           lavamentivorans DS-1
          Length = 287

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 54/193 (27%), Positives = 94/193 (48%), Gaps = 6/193 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITG  +GIG   V + L EG K +A  D+ +  G++++ EL    G    + R++V
Sbjct: 7   KVAIITGGTSGIGRGTVDLFLKEGAKVVAA-DLQDHKGEAMEREL----GENFSYCRANV 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN-----VTALITSTLKA 352
            +E+    +++  V++ G +D++ NNA      +G   + I++N     V  L+   +  
Sbjct: 62  AHEDEVKNLVDHTVKKFGKLDILFNNAGY--GGVGGELQEIDMNGFDETVGVLLKGVVLG 119

Query: 353 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            +    H    K G++I+ +SVA L   +   +Y A K+AV  FS C       +   VR
Sbjct: 120 YKYAVPHMKAQKSGSIISTASVAGLQAGYGPLVYSACKAAVHHFSRCAAL--ELAPHFVR 177

Query: 530 VLTVCFGATDTAL 568
              +C G   T++
Sbjct: 178 SNAICPGGIATSI 190


>UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4;
           Legionella pneumophila|Rep: Acetyoacetyl CoA reductase -
           Legionella pneumophila (strain Corby)
          Length = 248

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 49/172 (28%), Positives = 84/172 (48%), Gaps = 7/172 (4%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE-EAGKSLQVELNSKYGNKTKFYRS 181
           + VV ITG    IG +V +  LD   KH+  LD+   + G+    +L ++      F   
Sbjct: 4   NNVVLITGGTGDIGTAVAK-QLDSTFKHVIALDLVSYDEGEVWLHDLKTQGYKNINFRHM 62

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 343
           DVT+ E    ++  +++E GGIDV+INNA +  D++        + + + VN+  +   T
Sbjct: 63  DVTDYEQCAEVIGLIIEEFGGIDVLINNAGITRDAVFTKMTKRQWDEVLRVNLDGMFNVT 122

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499
            + +E M     G+   ++NVSSV A         Y A+K+ V  F+  + +
Sbjct: 123 KQVVESMKVQESGR---IVNVSSVNAQKGQFSQANYAASKAGVYGFTKSLAQ 171


>UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain
           dehydrogenase/reductase SDR - Verminephrobacter eiseniae
           (strain EF01-2)
          Length = 265

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITGA +GIG +   +   EG + I + D+  E G++  V    + G +  F ++DV
Sbjct: 16  KVALITGAGSGIGRATALLFATEGAQ-IVVCDLDPEGGQAT-VRAIEQAGAQALFVQADV 73

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 349
                    +   ++    +DV+ NNA +      ++ S   +   + VNV ++   + +
Sbjct: 74  AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A+ +M +  GG   ++IN  S   L        Y A K AV+  +  +   +H  +  +R
Sbjct: 134 AVPVMAEQGGG---SIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMAL-DHGPQR-IR 188

Query: 530 VLTVCFGATDTALLTDE 580
           V +VC G TDTA+L DE
Sbjct: 189 VNSVCPGDTDTAMLRDE 205


>UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -
           Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 249

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 57/194 (29%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K+  +TGA++GIG +    L + G K + I     +  + L+ ++ +K G +      DV
Sbjct: 7   KIALVTGASSGIGAATAAKLAEAGAK-VGIAARRTDKLEDLKKKIEAK-GGEALVIEMDV 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM--ND----SIGIYKKAIEVNVTALITSTLK 349
            +       +  +V   G ID+++NNA LM  +D     +  +++ ++VNV  L+ +T  
Sbjct: 65  VDTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTTAA 124

Query: 350 AI-EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
            + +++ +HS    G V N+SS+A       + +Y ATK AV  FS+ + R E   K G+
Sbjct: 125 VLPQMIKQHS----GHVFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGL-RMEVGQKHGI 179

Query: 527 RVLTVCFGATDTAL 568
           RV  +  GA  T L
Sbjct: 180 RVTCIQPGAVATEL 193


>UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=3; Leptospira|Rep: 3-oxoacyl-[acyl-carrier
           protein] reductase - Leptospira interrogans
          Length = 247

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K+K V +TG+  GIG         EG K+     I    G S Q  +    G+  K + +
Sbjct: 8   KNKTVLVTGSTRGIGRYFA-----EGFKNAGA--IVYGTGSS-QESIKKFDGSGIKGFAA 59

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 355
           D+   +    I+ ++V+E G +DV++NNA + ++    + K  E+   +    T   +A 
Sbjct: 60  DIRQPDVMTPIIESIVKEHGRLDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRAC 119

Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
               K    KGG +IN++S+  +  + +  +Y  TK AV+  +  +     +  +G RV 
Sbjct: 120 TAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVINMTRALA--VEWIGSGYRVN 177

Query: 536 TVCFGATDT 562
            +C G  DT
Sbjct: 178 AICPGFIDT 186


>UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Burkholderiaceae|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 252

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 51/182 (28%), Positives = 91/182 (50%), Gaps = 6/182 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +KV  +TGAA+G+G +   +L  EG + + + DI E+AG++L  E+    G+   F R D
Sbjct: 6   NKVALVTGAASGVGRADALLLAAEGAR-VVLTDIDEDAGRALAREI----GDAALFVRHD 60

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 346
           + +E  +   + + +   G +DV++NNAA+       + S+  +++ +  N         
Sbjct: 61  IADEAGWQHAIASTLDRFGRLDVLVNNAAICPVGSIEDTSLDTWRRVMRTNADGYFLGCK 120

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
            AI  M        G+++ +SSVAAL    +M  Y  +K AV   +  V    H  ++G 
Sbjct: 121 YAIGAM--KGNDTPGSIVMMSSVAALGGLPMMCAYTGSKGAVTALARSVA--VHCKRSGY 176

Query: 527 RV 532
           R+
Sbjct: 177 RI 178


>UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=3; Frankia|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Frankia sp.
           (strain CcI3)
          Length = 291

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 56/195 (28%), Positives = 92/195 (47%), Gaps = 4/195 (2%)
 Frame = +2

Query: 20  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTNEE 199
           ITGA++GIG +      D G + + +   +E     +   L ++YG +      D+ +E 
Sbjct: 14  ITGASSGIGAAFAEAYADRGARLVLVAP-SEPRLWMVAERLGARYGTEAHVIAVDLADER 72

Query: 200 HFLGILNAVVQEQGGIDVVINNAALMN----DSIGIYKKAIEVNVTALITSTLKAIEIMG 367
               +  AV +    +D+++NNA          +   +   EV +  +    +  + + G
Sbjct: 73  GPDRLAEAVAEAGLEVDILVNNAGFGTRGPYHELSADRDHREVMLNVVAVERVAHLFLPG 132

Query: 368 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCF 547
             + G+G TVINVSS +       M +Y A+K+ VL FS  +G    + + GVRVL +C 
Sbjct: 133 MVARGRG-TVINVSSTSGFQAVPYMTVYGASKAFVLSFS--IGLWAEYRRRGVRVLALCP 189

Query: 548 GATDTALLTDEKLGT 592
           G TDT     E LGT
Sbjct: 190 GPTDTEFF--EVLGT 202


>UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain
           dehydrogenase/reductase SDR - Acidobacteria bacterium
           (strain Ellin345)
          Length = 261

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 59/196 (30%), Positives = 93/196 (47%), Gaps = 7/196 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           +D+VV ITG   GIG ++ R +  EG     I+   +E       +   + G     +  
Sbjct: 28  EDQVVLITGGNRGIGLAMARAVAKEGAS--VIITGRDEHTLHHAADQIKRDGGTVVSHVC 85

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 340
           DV +E+    +  A+ +    IDV++NNA L          S+  ++  IE N+T     
Sbjct: 86  DVRDEDSVDELFAAIHRHYSQIDVLVNNAGLAQRNAQVDHLSLEAWQACIETNLTGAFLC 145

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
           T  A+ +M       G TV+N  SVAA T    M  Y A+K+ +L F+N +   E     
Sbjct: 146 TRAALPMMSP-----GATVVNNVSVAANTAFPGMAAYSASKAGLLAFTNTL--REELRPR 198

Query: 521 GVRVLTVCFGATDTAL 568
           G+RV+++  GATDT +
Sbjct: 199 GIRVISLVPGATDTEI 214


>UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase
           precursor; n=2; Clostridium difficile|Rep: Probable
           short chain dehydrogenase precursor - Clostridium
           difficile (strain 630)
          Length = 245

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 49/209 (23%), Positives = 99/209 (47%), Gaps = 6/209 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K K V ITG A GIG+++ +    EG   +   + +E   K L   LN K     K +++
Sbjct: 2   KKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKELYTILNEK-NFSVKLFKA 60

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 343
           +++N E    +++  ++E GG+DV++NNA +  D +        +   + +N+      +
Sbjct: 61  NISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDEDWDNMMNINLKGSFYCS 120

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             A++ M      K G +IN+SS+  ++ +     Y  TK+ ++  +  + +      + 
Sbjct: 121 QVALKYM---ISEKKGNIINISSIWGISGASCEVHYSITKAGIIGMTKALAK--EVGPSN 175

Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLE 610
           +RV ++  G  +T +L+       D  +E
Sbjct: 176 IRVNSIAPGVINTDMLSGYNEEDIDALVE 204


>UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Roseiflexus sp. RS-1
          Length = 246

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 58/196 (29%), Positives = 92/196 (46%), Gaps = 5/196 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K KV  +TGA  GIG++       EG  H+A++DI   AG    V   ++   +    ++
Sbjct: 4   KGKVAIVTGAGHGIGKATAIAFAREGA-HVAVVDI-NMAGAEATVAEITRLDGRALAVQA 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           DV+       ++  V+   G IDV++NNA +  D+  +  K  E    A+I   LK + +
Sbjct: 62  DVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLV--KMTEQQWDAVINVNLKGVWL 119

Query: 362 MGK----HSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             +    H   +G G++INVSS+  L  +     Y ATK  V+  +    R      +GV
Sbjct: 120 CARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWAR--ELGPSGV 177

Query: 527 RVLTVCFGATDTALLT 574
           RV  V  G   T ++T
Sbjct: 178 RVNAVTPGFIATEMIT 193


>UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=1;
           Algoriphagus sp. PR1|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Algoriphagus
           sp. PR1
          Length = 265

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 54/209 (25%), Positives = 105/209 (50%), Gaps = 8/209 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV+ +TG+ TGIG+++ + ++ EG K + I  + E+ G+ +  EL +   +  K +  D+
Sbjct: 6   KVIIVTGSTTGIGKAIAKKVVSEGAK-VIIHGLEEDLGQQVVSELGA---DNAKLHIEDI 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 349
           +NE     +++  V+  G +D ++NNAA++  S           + +EVN  +    T  
Sbjct: 62  SNEGAAQRLVDIAVKTWGKLDSIVNNAAIVAASTLFDTDKAFLNRILEVNTISPFLLTQA 121

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           AI  + ++     G V+N+ S+ A +  H +  Y  +K A++  +  +G    F + GVR
Sbjct: 122 AISQLIQNK----GAVLNIGSINAYSGEHNLLAYSISKGALMTMTRNLG-DSLFRENGVR 176

Query: 530 VLTVCFG--ATDTALLTDEKLGTFDKYLE 610
           V  +  G   T+  +   ++ G  D + E
Sbjct: 177 VNQINPGWVLTENEIARKKEHGLSDTWYE 205


>UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Polaribacter dokdonensis MED152|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaribacter dokdonensis
           MED152
          Length = 259

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 59/193 (30%), Positives = 95/193 (49%), Gaps = 8/193 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K   ITGA++G+G+   +I    G   + I+  +++  + L+ +L  K+G        D+
Sbjct: 3   KTALITGASSGLGKEFAKIHAKNG-GDLVIVARSKDKLQKLKEKLEKKHGVHVSIIEKDL 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG-IYKKA-------IEVNVTALITST 343
           T       + N V   +  ID +INNA      IG  +++A       I++N+ AL   T
Sbjct: 62  TEPNAAQEVYNFVKFSKIEIDYLINNAGF--GGIGKFHERAWAQDLAMIQLNIIALTDLT 119

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
            K +    + + GK   ++NVSS A+L    +  +YFATK+ V  FSN +    H +K  
Sbjct: 120 RKFLPDFVERNQGK---ILNVSSTASLMAGPMQAVYFATKAFVTSFSNAIAEELHDTK-- 174

Query: 524 VRVLTVCFGATDT 562
           V V T+  GAT T
Sbjct: 175 VTVTTLMPGATKT 187


>UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Chlorobium/Pelodictyon group|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Chlorobium phaeobacteroides (strain DSM 266)
          Length = 280

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 57/199 (28%), Positives = 99/199 (49%), Gaps = 6/199 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K   +TGAA+GIG ++   L++ G + + + DI + AG        +  G        DV
Sbjct: 8   KNAIVTGAASGIGFALAVGLIERGAR-VWVADI-DSAGVERAA---ASLGAGAHPVTLDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349
            +   F  ++  V ++ GGID + NNA +++             + I+VN+  ++  TL 
Sbjct: 63  RDAVAFRDLVAGVARDAGGIDFLFNNAGILHSGEVCEFDEEQCNRIIDVNIRGVVNGTLA 122

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A  +M +    + G ++N +S+A L  + ++  Y  TK AV+ FS+ + R E   + GVR
Sbjct: 123 AYPLMVRQ---RSGHIVNTASLAGLAPAPLLSTYAMTKHAVVGFSSSL-RFE-AERYGVR 177

Query: 530 VLTVCFGATDTALLTDEKL 586
           V  +C    DT LL +E +
Sbjct: 178 VSAICPAGVDTPLLDEEAI 196


>UniRef50_Q2U0U8 Cluster: Dehydrogenases with different
           specificities; n=2; Pezizomycotina|Rep: Dehydrogenases
           with different specificities - Aspergillus oryzae
          Length = 271

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 57/215 (26%), Positives = 101/215 (46%), Gaps = 23/215 (10%)
 Frame = +2

Query: 11  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN------KTKF 172
           +  ITGAA+GIG +       +G   IA+LD+ + A +++Q E+NS+         + + 
Sbjct: 6   IALITGAASGIGRACAHTFARDGASGIALLDLDKTALETVQAEINSQSSQDKTARCRVEI 65

Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-------YKKAIEVNVTA 328
           Y  +VT+E     ++N+  Q    +D V+N A + M    G        +++ ++VN+T 
Sbjct: 66  YPVNVTDENRVDEVINSAAQTFSRLDYVVNAAGIAMKHQGGAAFAETSDWQRILDVNLTG 125

Query: 329 LITSTLKAIEIMGKHS------GGK---GGTVINVSSVAALTQSHVMPIYFATKSAVLQF 481
                  A  IM           G+    G+++N SS+  +    +   Y ATK AV+  
Sbjct: 126 TFFVLRAAARIMLSQEPIRSSIDGRPLQRGSIVNFSSIQGVAGIPLSTAYTATKHAVIGL 185

Query: 482 SNCVGRPEHFSKTGVRVLTVCFGATDTALLTDEKL 586
           +      E ++K G+R+  +C G T+T + T   L
Sbjct: 186 TRTAS--EDYAKDGLRINAICPGYTETPMTTKSPL 218


>UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;
           n=13; Bacteria|Rep: Uncharacterized oxidoreductase
           SSP1627 - Staphylococcus saprophyticus subsp.
           saprophyticus (strain ATCC 15305 /DSM 20229)
          Length = 246

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 58/196 (29%), Positives = 91/196 (46%), Gaps = 7/196 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178
           KDKVV ITGA++GIGE  V +L + G K    L +       L+ ++  K G +     +
Sbjct: 5   KDKVVVITGASSGIGEETVNLLSENGAK----LVLGARRLDRLE-KIQQKVGHDSVSIKK 59

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 340
           +DVT  +    ++     + G IDV+INNA LM  S         + + I+VN+  ++  
Sbjct: 60  TDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLYG 119

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               +  M K    K G +IN++SVA         +Y  TK AV   +  + + E    +
Sbjct: 120 IGAVLPYMRKQ---KSGHIINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVGS 176

Query: 521 GVRVLTVCFGATDTAL 568
            +R   +  GA  T L
Sbjct: 177 NIRTTILSPGAVSTEL 192


>UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16;
           Mycobacterium|Rep: Probable oxidoreductase ephD -
           Mycobacterium bovis
          Length = 592

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 56/195 (28%), Positives = 91/195 (46%), Gaps = 6/195 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           D +V +TGA +GIG         EG + I I DI E   K    E+ ++ G     Y  D
Sbjct: 324 DTLVSVTGAGSGIGRETALAFAREGAE-IVISDIDEATVKDTAAEIAAR-GGIAYPYVLD 381

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 346
           V++ E        V  E G  D+V+NNA +      ++     + + + VN+  ++    
Sbjct: 382 VSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCR 441

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
              + + +   G GG ++NVSS+AA      +  Y  +K+A   FS+C+ R E     GV
Sbjct: 442 AFGQRLVER--GTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL-RAE-LDAAGV 497

Query: 527 RVLTVCFGATDTALL 571
            + T+C G  DT ++
Sbjct: 498 GLTTICPGVIDTNIV 512


>UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24;
           Epsilonproteobacteria|Rep: 3-OXOACYL-REDUCTASE -
           Wolinella succinogenes
          Length = 247

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 54/217 (24%), Positives = 97/217 (44%), Gaps = 7/217 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K V ITG++ GIG  + R+L + G+K              L+ E+ +K G +      D 
Sbjct: 6   KNVLITGSSRGIGADIARVLAEMGLKVWINYRSQSSLADELKAEIEAK-GGQAAVISFDA 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349
           T+EE F+  +  ++   G +  ++NNA + ND + I      ++  IE N+T+    + +
Sbjct: 65  TDEEAFISGIKTIIDADGELAYLVNNAGITNDKLAIRMKTEEFRSVIEANLTSAFIGSRE 124

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A++ M K    + G+V+N+SS+     +     Y A+K  ++  +               
Sbjct: 125 ALKSMSKQ---RFGSVVNISSIVGERGNAGQTNYSASKGGMIAMTKSFAFEGAPRNVRFN 181

Query: 530 VLTVCFGATD-TALLTDEKLGTFDKYLEFFMLGPTKE 637
            +T  F  TD T  L +E    + K +     G +KE
Sbjct: 182 CVTPGFIQTDMTHGLKEEVKEAYIKNIPLGRFGDSKE 218


>UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 251

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 58/203 (28%), Positives = 95/203 (46%), Gaps = 6/203 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K   +TGA +GIG ++      EG + +A+ D+ E A + +  E+    G      R+DV
Sbjct: 7   KRTIVTGAGSGIGRAIALRFAAEGAR-VALADVDEGAARKVAAEI----GEGCLVQRTDV 61

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 349
           T  E   G++    +  GG++V++NNA +         S   +++ + VN+         
Sbjct: 62  TVAEEVEGLVRLATERWGGLEVMVNNAGVGVAATAPQTSEEDFERVLAVNLRGTFLGMKY 121

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           AI  + + SG  GG VIN+SS+AAL        Y A K  +L  +   G  +H  + GVR
Sbjct: 122 AIPAI-RDSG--GGAVINMSSIAALVGLKDRAAYSAAKGGILALTR-AGAIDHIHE-GVR 176

Query: 530 VLTVCFGATDTALLTDEKLGTFD 598
           V  +  G  +T  ++    G  D
Sbjct: 177 VNCIAPGTVETPWISRITAGYAD 199


>UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3;
           Lactobacillus reuteri|Rep: Short-chain dehydrogenase -
           Lactobacillus reuteri
          Length = 277

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 8/195 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY----GNKTK 169
           +++VV ITG ++GIG+     L  E  +  AI+ +     + LQ E+  K     G    
Sbjct: 12  RNEVVLITGGSSGIGKE----LAFEAARRGAIVVVVSRNLEKLQ-EVAKKCLILSGRPAF 66

Query: 170 FYRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 349
            Y+ DVT+ +    +L+ V  E GGIDV+IN+A L  D I + K++       + T+ L 
Sbjct: 67  AYQLDVTDPDQIDDVLSKVQHEVGGIDVLINSAGL-GDFIPVVKESYSSMEKMVHTNLLA 125

Query: 350 AIEI---MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517
            + I   + K    +G G +IN+ S+A    +    +Y ATK+ V+QF N V R E  + 
Sbjct: 126 LMYISRCVAKQMMDQGYGAIINMGSLAGKLPTPNSAVYSATKAGVIQFDN-VLRME-VAD 183

Query: 518 TGVRVLTVCFGATDT 562
            GV+VLTV  G  DT
Sbjct: 184 YGVQVLTVNPGPIDT 198


>UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales
           bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales
           bacterium HTCC2150
          Length = 279

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 7/199 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGKSLQVELNSKYGNKTKFYR 178
           K+K V +TGAA G+G +     L +G  ++ + D+ AE+  +S+Q  +  ++        
Sbjct: 23  KNKTVIVTGAAQGLGYACALRFLQDGA-NVVMADVNAEKLAESVQDLI--EFDGAVSSMV 79

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 352
            DVT  E+   ++   V   G +DV+INNA +  + D + I     +  +   +      
Sbjct: 80  CDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGAFIG 139

Query: 353 IEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN--CVGRPEHFSKT 520
            +I GK   + GKGG +IN+SS+ AL  + ++  Y  +K  + Q +N   VG   H    
Sbjct: 140 TQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPH---- 195

Query: 521 GVRVLTVCFGATDTALLTD 577
            +RV  +  G   T ++ D
Sbjct: 196 NIRVCGIGPGTILTDMVAD 214


>UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Bacillus coagulans 36D1|Rep: Short-chain
           dehydrogenase/reductase SDR - Bacillus coagulans 36D1
          Length = 262

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 52/195 (26%), Positives = 91/195 (46%), Gaps = 7/195 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG   GIG     + L  G  ++ + D+++E G+    ++    G +  F R+DV
Sbjct: 9   KVAIVTGGGGGIGREAC-LKLAAGGANVVVADLSDELGEETAGKIREN-GGEAIFVRTDV 66

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346
           +  +     +   +   G ID+++NNA        L++    ++ K + +NV  +     
Sbjct: 67  SKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVFLGMK 126

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             +  M      K GT++N +SVA L  +  M  Y A+K AV+  +   G     + +GV
Sbjct: 127 YVLPHMISQ---KSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAG--IEAAPSGV 181

Query: 527 RVLTVCFGATDTALL 571
           RV  VC G  DT ++
Sbjct: 182 RVNAVCPGVVDTEMM 196


>UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Delftia acidovorans SPH-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Delftia acidovorans SPH-1
          Length = 301

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 61/192 (31%), Positives = 90/192 (46%), Gaps = 6/192 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K V +TGA+ GIGE   R L   G K + I    +   K L  EL        +F   D+
Sbjct: 51  KTVLVTGASMGIGEVFARELARRGAKVVLIARSRDRLEK-LASELPG-----AEFLVEDL 104

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349
                   + +AV       D+++NNA           ++ + ++ I++NV AL+  T  
Sbjct: 105 ATPGAARRVFDAVSARGLLPDLLVNNAGFGTHGRFDELALDMQRETIDLNVGALVELTHL 164

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            +  + +  GG    VIN++S AA      M +Y ATK+ VL FS  +     +   GVR
Sbjct: 165 CLPALEQRQGG----VINIASTAAFQPVPYMAVYAATKAFVLSFSEALW--AEYRPRGVR 218

Query: 530 VLTVCFGATDTA 565
           VL +C GATDTA
Sbjct: 219 VLALCPGATDTA 230


>UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid
           dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or
           20-beta)-hydroxysteroid dehydrogenase - Mycobacterium
           bovis
          Length = 260

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 53/193 (27%), Positives = 96/193 (49%), Gaps = 6/193 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ++G A G+G S VR ++ EG K +   DI +E GK++  EL     +  ++   DV
Sbjct: 8   KVALVSGGARGMGASHVRAMVAEGAK-VVFGDILDEEGKAVAAEL----ADAARYVHLDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349
           T    +   ++  V   GG+ V++NNA ++N       ++  +++ ++VN+T +      
Sbjct: 63  TQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRA 122

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            ++ M K +G   G++IN+SS+  L  +     Y ATK AV   +           +G+R
Sbjct: 123 VVKPM-KEAG--RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTAL--ELGPSGIR 177

Query: 530 VLTVCFGATDTAL 568
           V ++  G   T +
Sbjct: 178 VNSIHPGLVKTPM 190


>UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium
           japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
          Length = 248

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITGA +GIG ++ R+   EG K + + D+A E G +L   L +  G+   F   DV
Sbjct: 7   KVAVITGAGSGIGAAIARLFAVEGAK-VLLGDLA-EGGAALAAGLAAD-GHAAGFQHVDV 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367
           T+E     ++ A V   G +D+++ NA +      I++  + V+   +I   L  + I  
Sbjct: 64  TDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIHELDL-VDWRRVIDVDLTGVAICN 122

Query: 368 KHSGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           K + G      GG ++N++S+ A         Y A K+AV+  +  V     ++  G+R 
Sbjct: 123 KFAAGIMRATGGGAIVNMASILAHVGQENSNAYSAAKAAVVNLTRSVALT--YALQGIRA 180

Query: 533 LTVCFGATDTALL 571
             V  G  DT LL
Sbjct: 181 NCVSPGYVDTPLL 193


>UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=1; Pseudomonas syringae pv. phaseolicola
           1448A|Rep: 3-oxoacyl-[acyl-carrier protein] reductase -
           Pseudomonas syringae pv. phaseolicola (strain 1448A /
           Race 6)
          Length = 282

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 59/198 (29%), Positives = 101/198 (51%), Gaps = 6/198 (3%)
 Frame = +2

Query: 11  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 190
           VV ITGAA GIG+++   L+  G++ I + DI E   K L+V L    G     Y  D+T
Sbjct: 4   VVLITGAAGGIGQAICAQLIRRGMQLI-LADIDE---KQLRV-LAESLGEDAFPYVVDLT 58

Query: 191 NEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLKA 352
           N+E   G++  +  E G +DV+INNAA+         S+    + + +N+ A +  T  A
Sbjct: 59  NQESLAGLMTYIESEFGRLDVLINNAAIAVVEAFDTRSVESISRELNINLVAPLILTRLA 118

Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           I ++ + +  +   VI+  S+  +  +   PIY A+K  +      +G     ++ G++V
Sbjct: 119 IPLLKRSNDAR---VISTVSLGGVFPTPESPIYCASKFGLRGAMLSIGL--DLAEKGIKV 173

Query: 533 LTVCFGATDTALLTDEKL 586
            ++   ATDT +L  E +
Sbjct: 174 GSILPTATDTQMLRKEAI 191


>UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4;
           Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase
           - Clostridium perfringens (strain SM101 / Type A)
          Length = 253

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 63/205 (30%), Positives = 97/205 (47%), Gaps = 10/205 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 178
           K+KVV +TG   GIG + V+  LD G K +A+    +E       ELN    N     + 
Sbjct: 9   KNKVVIVTGGTRGIGFATVKKFLDHGAK-VALCGSRKETVDKALEELNYINPNYDAIGFY 67

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALIT 337
            ++ +      +++ V+++ G ID++INNA  ++D+  IY        K I++NV A+  
Sbjct: 68  PNLLDSNEVKEMVDKVLEKWGTIDILINNAG-VSDNKSIYTQSDEDFSKIIDINVKAIFN 126

Query: 338 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517
            T    EIM      K G ++N SSV +L        Y  +K AV   +  + R     +
Sbjct: 127 CTKAVSEIM---KNKKYGVILNTSSVVSLYGQKTGVGYPTSKFAVNGLTKSLAR--ELGR 181

Query: 518 TGVRVLTVCFG--ATDTALLTDEKL 586
            G+RV  V  G  ATD     D+KL
Sbjct: 182 DGIRVNAVAPGIIATDMVAALDKKL 206


>UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=3;
           Proteobacteria|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Erythrobacter
           sp. NAP1
          Length = 267

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 61/211 (28%), Positives = 103/211 (48%), Gaps = 7/211 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K V ITG++ GIGE + R    EG   +     AE+  K     L++   ++T     DV
Sbjct: 10  KTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADT-LDA---DRTLTCPGDV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITSTL 346
           ++ +    I+   V+  GG+D ++NNA +   S+ ++K       + I++NV  +I    
Sbjct: 66  SSSDFANEIVAKTVERFGGLDCLVNNAGVGGSSM-LHKTDDEEIDRIIDINVKGVIYLCR 124

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
            AI  + K     GG++IN+SSV+ +    ++PIY A+K A+   +   G  +     G+
Sbjct: 125 AAIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTR--GLAQQIGGMGI 182

Query: 527 RVLTVCFGATDTALLTDEKLGTFDKYLEFFM 619
           RV  +    T + ++ D  L   D  LE FM
Sbjct: 183 RVNAINPSITRSDMV-DGILAN-DALLEAFM 211


>UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 253

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 54/192 (28%), Positives = 88/192 (45%), Gaps = 5/192 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KVV ITG ATGIG +       +G + + + D+ + A ++  V L  + G    F R+DV
Sbjct: 10  KVVLITGGATGIGRATALAFAQQGAR-VVVGDVDDRAAET--VRLIEESGGTALFVRTDV 66

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367
           T+      ++   V   GG+ V  NNA ++  + G   +  E +    I   LK + +  
Sbjct: 67  TSAADVQQLVRTTVDTYGGLHVAFNNAGILPPT-GPLAEQSEDDFDRTIAVDLKGVFLAL 125

Query: 368 KH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           K+     +   GG++IN +SVA +     M  Y A K  V+  +        ++  GVRV
Sbjct: 126 KYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAA--IDYAAAGVRV 183

Query: 533 LTVCFGATDTAL 568
             +  G  DT +
Sbjct: 184 NALAPGLVDTPM 195


>UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Short chain dehydrogenase -
           marine gamma proteobacterium HTCC2080
          Length = 291

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 48/181 (26%), Positives = 86/181 (47%), Gaps = 2/181 (1%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K + ITGAA+G+G ++ +    EG   + I DI +E G  +  +LN +Y N   F   ++
Sbjct: 2   KRILITGAASGLGLALAKKYASEGWS-VCIADIQDEEGIKIAAQLNEEYANDCFFQHLNI 60

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGIYK-KAIEVNVTALITSTLKAIEI 361
           T++  +  ++  + +   G+D ++NNA +  +  I  +  K  +  V   +   +K   +
Sbjct: 61  TSDTQWQELVALISERWQGLDALVNNAGVGASGDIDTFSIKDFQWTVDINLMGAVKGCHV 120

Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541
                    G +INV+S+A L     M  Y  +K+ ++ FS   G        GV+V  V
Sbjct: 121 CVPLLKESKGLLINVASMAGLLHMGSMSAYNVSKAGMVAFSE--GLLSELDPYGVKVSVV 178

Query: 542 C 544
           C
Sbjct: 179 C 179


>UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=18; Bacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Arthrobacter sp.
           (strain FB24)
          Length = 263

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 58/208 (27%), Positives = 98/208 (47%), Gaps = 18/208 (8%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK-FYR 178
           K  V  ITG A+G+G +  R L D G   + ++D+    G++   ELN+  G  T  F  
Sbjct: 4   KGTVALITGGASGLGAATARRLFDAGAS-VVLVDLPSSRGEAFAAELNAASGAGTAVFVP 62

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS----------IGIYKKAIEV---- 316
           +DVT+EE     + A V   G + +V+N A +              +  + + I++    
Sbjct: 63  ADVTSEEQVQAAVAAAV-ALGPLRIVVNCAGIATPGKVLGRDGVLPLDTFSRVIQINLVG 121

Query: 317 --NVTALITSTLKAIEIMGKHSGG-KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 487
             NV  L  + + A E +    GG + G +IN +SVAA       P Y A+K AV   + 
Sbjct: 122 TFNVIRLAAAAMAATEPVSTELGGPERGVIINTASVAAFDGQIGQPAYAASKGAVAAMTL 181

Query: 488 CVGRPEHFSKTGVRVLTVCFGATDTALL 571
            + R    +++ +RV+T+  G  +T ++
Sbjct: 182 PIAR--ELARSLIRVVTIAPGIFETPMM 207


>UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 249

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 51/188 (27%), Positives = 93/188 (49%), Gaps = 7/188 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K+KV  +TG  +G GE++ R    EG K + I DI    G+ +     + + +   F + 
Sbjct: 15  KNKVAIVTGGGSGFGEAIARRFAGEGCK-VTIADIDAVGGERVA----NVHPHSMLFVKM 69

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALITS 340
           DVTNEE +  +L   + + G +DV +NNA        ++ +    + K   VNV ++  +
Sbjct: 70  DVTNEEDWERVLETTLAKWGRVDVCVNNAGTSYRNKPTLDVIEDEFDKVFNVNVKSIFYA 129

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
           T   I      + G+GG++IN++S+ A      +  Y A+K+AV+  +   G    +   
Sbjct: 130 TRHFIP--NVINQGEGGSMINIASIGASRPRAGLVWYNASKAAVVNATK--GLAAEYGPK 185

Query: 521 GVRVLTVC 544
            +R+ ++C
Sbjct: 186 NIRINSIC 193


>UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=2; Halobacteriaceae|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 254

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 55/211 (26%), Positives = 98/211 (46%), Gaps = 9/211 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKTKF 172
           +DKV  +TG A+G G ++ R   + G   + + D  +   E GK     + ++      F
Sbjct: 6   EDKVAVVTGGASGFGRAICRRYAEHGA-DVIVADRQQDPREGGKPTHELVEAETDRTAHF 64

Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 334
              DVT+ +  L +  A  +E GGID+++NNA +         +   Y + ++VN   + 
Sbjct: 65  VECDVTDPDD-LEVAVAAAEELGGIDIMVNNAGISEIADFYETTEEDYDRLMDVNTKGVF 123

Query: 335 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFS 514
                A E M ++    GGTVIN+SS   +  + ++  Y  +K AV  F+  +   +  S
Sbjct: 124 FGAQVATEAMRENG---GGTVINMSSSGGIRGTGLLVNYCTSKGAVRLFTYALA--DRLS 178

Query: 515 KTGVRVLTVCFGATDTALLTDEKLGTFDKYL 607
              +RV  +  G + T +  DE++    K +
Sbjct: 179 NYNIRVNAIHPGYSKTQMFEDERIDDTTKMM 209


>UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to
           ENSANGP00000025535; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000025535 - Nasonia
           vitripennis
          Length = 254

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 58/198 (29%), Positives = 99/198 (50%), Gaps = 8/198 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGA+ GIG ++V  LLD G   + ++ +A    K  ++ ++ +   K      DV
Sbjct: 7   KVAVVTGASVGIGAAIVNKLLDNG---LIVVGLARRVEKVKEL-IDDRPEAKLHAVECDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLK 349
           TNEE+ +     + +  G +DV++NNA       L + S+  ++  ++VNV  L   T +
Sbjct: 63  TNEENVVTAFAWIKENLGSVDVLVNNAGVTKETTLSDGSLADWRNVLDVNVLGLCVCTRE 122

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHV--MPIYFATKSAVLQFSNCVGRPEHFSKTG 523
           A+  M +  G     +I++SS+A      V    +Y ATK AV   +  + R E  + T 
Sbjct: 123 AVRSMRECDG--ESVIIHISSLAGERVPAVPGFNVYPATKRAVNALAQTL-RHE-LAGTK 178

Query: 524 VRVLTVCFGATDTALLTD 577
           +RV T+  G   T L+ +
Sbjct: 179 IRVTTISPGLVATELMAN 196


>UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Leptospira interrogans
          Length = 259

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 50/192 (26%), Positives = 95/192 (49%), Gaps = 7/192 (3%)
 Frame = +2

Query: 8   KVVFITGAAT--GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KV  +TGAA+  G+G ++   +  EG   I ++D+ +E  +    ++  ++G KT     
Sbjct: 12  KVALVTGAASPRGLGRAIANTIAKEG-GDIVLVDLNKEQIEQAAADVAKEFGVKTLGLSC 70

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361
           +VT  E    ++  V ++ G +D ++NNA ++ D++ I  +  E     ++   LK + +
Sbjct: 71  NVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFI--RMSEQEFDFVLDVNLKGVFL 128

Query: 362 MGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
           M K++       + G ++N+SSV+ LT       Y ++K+ V+  +    R   F+   V
Sbjct: 129 MTKYASKLLLKAESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKVAAR--EFAGRNV 186

Query: 527 RVLTVCFGATDT 562
            V  VC G   T
Sbjct: 187 LVNAVCPGYVQT 198


>UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=3; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
           sp. (strain RHA1)
          Length = 258

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 52/184 (28%), Positives = 87/184 (47%), Gaps = 6/184 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K + +TG A GIG ++V+    EG   +   D+ EE G+ +  E +       +F R D+
Sbjct: 6   KRILVTGGAQGIGAAIVKAYAMEGAT-VRSYDLNEEGGRVVAEEASDAGPGVVEFSRLDI 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG------IYKKAIEVNVTALITSTLK 349
           T+ +    +  +  +E GGIDV++N A L   ++       +++    VNV   I +   
Sbjct: 65  TDGDATESLFRSAARELGGIDVLVNIAGLQRSAMAEEITDDLFESIYRVNVLGTIHTNQS 124

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A  IM   S G  G +IN  S++  T       Y ++K AV  ++  V R   +  +G+R
Sbjct: 125 AYRIM--QSAGT-GAIINFGSMSGFTGELANATYGSSKGAVHTWTRTVAR--EWGPSGIR 179

Query: 530 VLTV 541
           V  V
Sbjct: 180 VNAV 183


>UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus gnavus ATCC 29149|Rep: Putative
           uncharacterized protein - Ruminococcus gnavus ATCC 29149
          Length = 276

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 51/195 (26%), Positives = 94/195 (48%), Gaps = 7/195 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +K++ +TGA +GIG +V      EG   +A+    EE G ++ V    + G K +F + D
Sbjct: 13  EKIMLVTGATSGIGRAVAIRAAKEGATVVAV-GRNEERGAAV-VAAMEEAGGKGEFMKCD 70

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITST 343
           V+N++    +   + ++ G +DV +NNA ++  S  +       + + I+ N+ +     
Sbjct: 71  VSNKDAVKALFAEIQEKYGKLDVAVNNAGIVGASKTVEELEDDDWFQVIDANLNSCFFCC 130

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
            + +++M       GG ++NVSSVA +        Y A+K AV   +  V     ++  G
Sbjct: 131 REEVKLMQP----SGGAIVNVSSVAGMRGFPSAAAYVASKHAVSGLTKAVA--VDYATKG 184

Query: 524 VRVLTVCFGATDTAL 568
           +    +C   TDT L
Sbjct: 185 ITCNAICPAGTDTPL 199


>UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=9; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Nocardioides sp. (strain
           BAA-499 / JS614)
          Length = 259

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 8/198 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +V  ITG  +GIG + V+  + EG K + I DI +  G  L  +L     +   +   DV
Sbjct: 8   RVAVITGGCSGIGLATVQRFVQEGAK-VVIGDIDDARGHQLVEQLGG--ADVATYVHVDV 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA--------ALMNDSIGIYKKAIEVNVTALITST 343
           T++E    +        G +D+  NNA        ++++  +  ++K  EVN+T++    
Sbjct: 65  TSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNLTSVYLCC 124

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             A+  M +   G+G  +   S VA +  +     Y A+K  VL  +  +G    F++ G
Sbjct: 125 KAALPHMLEQ--GRGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELG--VQFARQG 180

Query: 524 VRVLTVCFGATDTALLTD 577
           VRV  +C G  +T LL +
Sbjct: 181 VRVNALCPGPVNTPLLQE 198


>UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=26; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia
           pneumoniae (Chlamydophila pneumoniae)
          Length = 248

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 52/197 (26%), Positives = 96/197 (48%), Gaps = 7/197 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K V +TG + GIG  +V++ L+ G   + I  + EE G+++ +E  +  G +  F R DV
Sbjct: 8   KKVIVTGGSRGIGLGIVKLFLENGAD-VEIWGLNEERGQAV-IESLTGLGGEVSFARVDV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349
           ++       +   + +   ID+++NNA +  D++ +      ++  I  N+T+L  +   
Sbjct: 66  SHNGGVKDCVQKFLDKHNKIDILVNNAGITRDNLLMRMSEDDWQSVISTNLTSLYYTCSS 125

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            I  M K    + G++INV+S+ A   S     Y A K+ ++ F+  + +        V 
Sbjct: 126 VIRHMIK---ARSGSIINVASIVAKIGSAGQTNYAAAKAGIIAFTKSLAKEVAARNIRVN 182

Query: 530 VLTVCFGATD-TALLTD 577
            L   F  TD T++L D
Sbjct: 183 CLAPGFIETDMTSVLND 199


>UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60;
           Bacteria|Rep: Sorbitol dehydrogenase - Rhodobacter
           sphaeroides (Rhodopseudomonas sphaeroides)
          Length = 256

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 51/188 (27%), Positives = 95/188 (50%), Gaps = 4/188 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K   ITG+A GIG +     + EG + +AI DI  EA ++   E+    G        DV
Sbjct: 6   KTALITGSARGIGRAFAEAYVREGAR-VAIADINLEAARATAAEI----GPAACAIALDV 60

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIEI 361
           T++      +  ++   G ID+++NNAAL + +  + I +++ +      ++ TL  ++ 
Sbjct: 61  TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120

Query: 362 MGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
           + +   +GG+GG +IN++S A      ++ +Y ATK+AV+  +   G   +  + G+ V 
Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGL--NLIRHGINVN 178

Query: 536 TVCFGATD 559
            +  G  D
Sbjct: 179 AIAPGVVD 186


>UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2;
           Rhodobacteraceae|Rep: Short-chain alcohol dehydrogenases
           - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 /
           NCIB 8253 / DSM158)
          Length = 247

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 58/201 (28%), Positives = 98/201 (48%), Gaps = 6/201 (2%)
 Frame = +2

Query: 14  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193
           + ITGA +GIG    R    EG   +A++D  E A    QV  +   G+    +  DVT+
Sbjct: 10  IVITGAGSGIGRESARQFAREGAT-LALIDRDEAAA---QVTADETGGH---VFALDVTD 62

Query: 194 EEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLKAI 355
           E     ++    +  GGID ++N+A ++     D IG+  +++ ++VN+T        A+
Sbjct: 63  EAAVETVVGRAAEALGGIDGLLNSAGILTMKTVDDIGVEEFRRVVDVNLTGTFLVCQAAL 122

Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
             + K        ++N++S  AL  S     Y A+K+AV+ FS  + +        VRV 
Sbjct: 123 PWLRKE---PKAAIVNIASAQALLPSLTGSAYAASKAAVMMFSKSIAKE---LAPAVRVN 176

Query: 536 TVCFGATDTALLTDEKLGTFD 598
            +C GAT+T  +TD+ +   D
Sbjct: 177 IICPGATETP-MTDQGVAPDD 196


>UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1;
           Leuconostoc mesenteroides subsp. mesenteroides ATCC
           8293|Rep: Putative uncharacterized protein - Leuconostoc
           mesenteroides subsp. mesenteroides (strain ATCC 8293
           /NCDO 523)
          Length = 247

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 62/201 (30%), Positives = 98/201 (48%), Gaps = 9/201 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV+ ITGA++GIGE++ +     G K I +    EE  K ++ ++ +  G + ++  +DV
Sbjct: 5   KVIVITGASSGIGEAIAKKQAAAGDK-IVLGARREENLKQIKADIEAG-GGQAEYLVTDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349
           T+ E    +    +   G IDV INNA LM  S+ I      + + I+VN+   +     
Sbjct: 63  TDVEQVKALAQKAMDAYGRIDVWINNAGLMPHSLLIDARIDDWNRMIDVNLKGTLYGIAA 122

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A  I    + G     IN+ SVA+L       +Y ATK AV   S  +   E  +   VR
Sbjct: 123 AQHIFHDQNTGH---FINLGSVASLYSHAGGAVYSATKWAVKAISESLREEEAQAGKNVR 179

Query: 530 VLTVCFGATDTAL---LTDEK 583
           V ++  GA ++ L   +TD K
Sbjct: 180 VTSLYPGAIESELVANMTDSK 200


>UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5;
           Proteobacteria|Rep: Short chain dehydrogenase -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 278

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 60/193 (31%), Positives = 86/193 (44%), Gaps = 7/193 (3%)
 Frame = +2

Query: 14  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193
           V ITGA TGIG +       EG + +A+    EEAG +L  EL +  GN+ +F  +DV  
Sbjct: 35  VLITGALTGIGRATAFAFAREGYR-VAVSGRREEAGNALAAELRA-LGNEAEFLLADVRF 92

Query: 194 EEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTLKA 352
           E     ++   V   G IDV +NNA        ++  S   Y +   VNV   + S    
Sbjct: 93  EADVRNLVEQTVVRFGRIDVAVNNAGTEGQLAPIVEQSAANYAETFGVNVLGTMLSLKHE 152

Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           + +M        G++IN+SSVA         +Y A+K AV   +         +  GVRV
Sbjct: 153 MRVMLAQG---SGSIINLSSVAGKVGIAGASVYVASKHAVEGLTKSAAL--EGAAAGVRV 207

Query: 533 LTVCFGATDTALL 571
             V  G   T +L
Sbjct: 208 NAVAPGPVATEML 220


>UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular
           organisms|Rep: Os07g0664000 protein - Oryza sativa
           subsp. japonica (Rice)
          Length = 572

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 9/197 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITG A+GIG++     +  G K + I DI ++ G S+  EL    G    + R DV
Sbjct: 314 KVAVITGGASGIGKATATEFIKNGAK-VIIADIQDDLGHSVAAEL----GPDAAYTRCDV 368

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA----ALMND-----SIGIYKKAIEVNVTALITS 340
            +E      +   V+  G +DV  NNA    AL  D      +G + + + VN  + + +
Sbjct: 369 ADEAQVAAAVGLAVKRHGRLDVFHNNAGIAGALPQDDMAAVDLGDFDRVMAVNARSTLAA 428

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
              A   M        G V+  SS A +     +P+Y  +K+ V+        P   ++ 
Sbjct: 429 VKHAARAMAPRC---SGCVLCTSSGAGVIPVPAVPVYSVSKATVIAIVRAAAEP--MARH 483

Query: 521 GVRVLTVCFGATDTALL 571
           G+RV  +  GAT T LL
Sbjct: 484 GLRVNAISPGATRTPLL 500


>UniRef50_Q7SI45 Cluster: Putative uncharacterized protein
           NCU00606.1; n=2; Sordariales|Rep: Putative
           uncharacterized protein NCU00606.1 - Neurospora crassa
          Length = 262

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 48/198 (24%), Positives = 96/198 (48%), Gaps = 8/198 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K V  TGAA G+G+ +    L  G  ++ I D+ ++   +++ E    Y ++    ++DV
Sbjct: 7   KTVLATGAAGGLGKVIAETFLAAGA-NVIICDVNQQRNSAVEEEWTRTYADRFLIKQTDV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 346
           +NE     +++A V + G +DV++NNAA+M+D       S  ++ + + +N+T    +T 
Sbjct: 66  SNEAAVQELIDASVAKFGRLDVLVNNAAIMDDFSPAGDCSKELWDRVMAINLTGPFLTTK 125

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS-NCVGRPEHFSKTG 523
            A++   K     GG +IN+ S A+         Y  +K+ ++  + N  G    ++  G
Sbjct: 126 AAVKQFEKQKQA-GGIIINIGSNASYMGFQSGAAYTVSKAGIMALTKNTAG---FYADKG 181

Query: 524 VRVLTVCFGATDTALLTD 577
           +  + +  G      + D
Sbjct: 182 IYTMALLLGGLTGTNIVD 199


>UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member
           10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR
           family member 10 - Homo sapiens (Human)
          Length = 270

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KVV +TG   GIG  +VR  ++ G + + I D  E  G++L+ EL         F   DV
Sbjct: 10  KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346
           T E+    +++  ++  G +D V+NNA            S   +++ +E+N+    T T 
Sbjct: 64  TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123

Query: 347 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
            A+  + K      G VIN+SS V A+ Q+  +P Y ATK AV   +  +   E  S  G
Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176

Query: 524 VRVLTVCFGATDTAL 568
           VRV  +  G   T L
Sbjct: 177 VRVNCISPGNIWTPL 191


>UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular
           organisms|Rep: Alcohol dehydrogenase - Bordetella
           parapertussis
          Length = 252

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 52/195 (26%), Positives = 89/195 (45%), Gaps = 5/195 (2%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K   +TGA +G GE +      EG K + + DI E  G+ +   +N+  G +  F R+DV
Sbjct: 6   KTAIVTGAGSGFGEGIAATFAREGAK-VVVADINEAGGQRVAAAINAA-GGQAVFVRADV 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367
           ++      +L A ++  GG+D+V+NNA   + +  +  +  E     +    +K+I +  
Sbjct: 64  SDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPML-EVEEDEFDRIYAINVKSIYLTA 122

Query: 368 KH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
           +H         GG+ IN++S AA+     +  Y  +K AV+  S  +          V  
Sbjct: 123 RHMVPHFRAHGGGSFINIASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNIRVNC 182

Query: 533 LTVCFGATDTALLTD 577
           +    GA  T LL D
Sbjct: 183 VNPVIGA--TGLLAD 195


>UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1;
           Terrabacter sp. DBF63|Rep: Short-chain
           dehydrogenase/redutase - Terrabacter sp. DBF63
          Length = 252

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 54/195 (27%), Positives = 91/195 (46%), Gaps = 7/195 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TG   GIG    ++L+D G + + + D++E+AG      ++   G+   F R+DV
Sbjct: 8   KVALVTGGGGGIGRETAKVLVDHGAR-VVVADLSEDAGNGTLEYIDG--GDAVAFVRADV 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346
           T+      ++ A V   G +D+  NNA        L + ++  + K I VN+T +  S +
Sbjct: 65  TDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLTGVFIS-M 123

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
           KA EI    + G GG++IN +S            Y  +K  V+  +        +S  G+
Sbjct: 124 KA-EIPQMLAQG-GGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAA--VEYSDKGI 179

Query: 527 RVLTVCFGATDTALL 571
           RV  V  G   T ++
Sbjct: 180 RVNAVLPGVIQTPMI 194


>UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 261

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 60/196 (30%), Positives = 91/196 (46%), Gaps = 11/196 (5%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITG   G G++    L + G  H+ + DI  +   +   EL +  G+ T     DV
Sbjct: 18  KVALITGGGRGFGKAFGAALTERGA-HVVLADIDGDVASAAAAELTALGGSATGV-TCDV 75

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTALITS 340
           T+E     ++  +V+  GG+D+++NNA L + +          G  ++  EVNV  ++  
Sbjct: 76  TDEARVGEVVADIVRAHGGLDILVNNAGLHSAAFNKPTAELGAGQIRRLFEVNVMGVVIC 135

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
           TL A + M   SG  G  V+N+SS AA         Y  +K AV  F+    R    +  
Sbjct: 136 TLAAKDAM---SGRAGAAVVNISSSAAYAN---RTAYGVSKLAVRGFTAQFAR--ELAAV 187

Query: 521 GVRVLTVCFG--ATDT 562
           GVRV  +  G   TDT
Sbjct: 188 GVRVNAIAPGLILTDT 203


>UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candidatus
           Pelagibacter ubique|Rep: Short chain dehydrogenase -
           Candidatus Pelagibacter ubique HTCC1002
          Length = 253

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 5/171 (2%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K+K VF+TG  +GIG S+V    ++G   +  +DI E+A   L +E  +K  +   F + 
Sbjct: 9   KNKRVFVTGGGSGIGASIVEHFCEQG-SEVYFIDINEKASNKLVLECKNKNFSVPTFIKC 67

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK---- 349
           D+ N +     ++ ++   G IDV++NNAA  ND      +  E      +   L+    
Sbjct: 68  DLLNIKDLQNTISKIIDNNGAIDVLVNNAA--NDERHSIDEVTEEFWNERMNINLRHYFF 125

Query: 350 AIEIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499
            ++ + K     K G++IN+ SV+ +     M  Y A KS V+  +    R
Sbjct: 126 TVQSVKKAMIANKSGSIINIGSVSWMIGQGGMAAYTAAKSGVVGLTRSFAR 176


>UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 286

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 48/181 (26%), Positives = 87/181 (48%), Gaps = 6/181 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +  F+TG   GIG ++  I L E   ++AILDI  E  +     +    G +   + +DV
Sbjct: 10  QAAFVTGGGGGIGRAIA-IRLAEAGANVAILDIIAERAEETATRIRET-GARALTFPADV 67

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 349
              +     ++      G +D+++NNA        +  S    +K I++N+ +++ +T  
Sbjct: 68  MESDALRAAIDQAAAAFGRLDILVNNAGGVSARPFLEQSERSMRKHIDINLMSMLVATQA 127

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A   M   +GGKGG++INV+S+ A   +    +Y A K+ +  F+  +      S  G+R
Sbjct: 128 AARHMV--AGGKGGSIINVASIEATRAAPNFAVYAACKAGMFSFTRSMAL--ELSGHGIR 183

Query: 530 V 532
           V
Sbjct: 184 V 184


>UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Polaromonas sp. JS666|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 265

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 56/204 (27%), Positives = 102/204 (50%), Gaps = 7/204 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE-AGKSLQVELNSKYGNKTKFYR 178
           K+K V +TG  + IG ++V     EG  HI I D+ E+ A K+ ++ L S   +  +  +
Sbjct: 6   KNKSVIVTGGGSNIGRAIVLGFAAEGA-HITIGDVDEQQAQKTAELALLSGAAS-AQVVK 63

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAA---LM---NDSIGIYKKAIEVNVTALITS 340
           +DVT  +    +  A V + GG+DV++NN     LM     +  +++K I +N   ++  
Sbjct: 64  TDVTQLDQVQAMFKAAVDKFGGVDVLVNNVGWDQLMFFTQTTPDLWQKIIAINYVGVLNC 123

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
           T  A+++M   +    G+++++SS A+        +Y   K+A+  F   + +     + 
Sbjct: 124 TKTALDLMIPRN---AGSIVSISSDASRQGEPREAVYGGVKAAINSFMKTIAKEN--GRY 178

Query: 521 GVRVLTVCFGATDTALLTDEKLGT 592
           G+R   VC G T  +  TDE  G+
Sbjct: 179 GIRCNVVCPGITIPS-TTDEVGGS 201


>UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3;
           Proteobacteria|Rep: P-cumic alcohol dehydrogenase -
           Pseudomonas putida
          Length = 252

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 59/194 (30%), Positives = 93/194 (47%), Gaps = 9/194 (4%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDKV  +TGAATGIG ++VR  L EG K + I D+  +  ++   EL     +      +
Sbjct: 4   KDKVAIVTGAATGIGNAIVRSYLAEGAK-VVIADV--KGAEAAAAELGE---DLALGVFA 57

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMN-------DSIGI--YKKAIEVNVTALI 334
           DV++ +    +  A +   G IDV++NNA +         +SI +  + K   VNV    
Sbjct: 58  DVSDPDSTKQMAKAALDRFGKIDVLVNNAGIFTGLNYVPMESISVADWDKLYSVNVKG-- 115

Query: 335 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFS 514
              L A  +      G GG +IN++SV A   +  M  Y ++K AV   +  + R    +
Sbjct: 116 -PWLCASAVSAAMREGGGGKIINIASVIAHIGAPFMLHYVSSKGAVAAMTRAMAREFATT 174

Query: 515 KTGVRVLTVCFGAT 556
           K G+ V ++  G T
Sbjct: 175 KAGISVNSISPGYT 188


>UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=1; Marinomonas
           sp. MED121|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Marinomonas sp.
           MED121
          Length = 259

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 57/185 (30%), Positives = 90/185 (48%), Gaps = 6/185 (3%)
 Frame = +2

Query: 14  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193
           V +TG A+GIGE++V+ L  +G   ++  DI EEAG+ L   LNS +G K  F   D+T+
Sbjct: 20  VLVTGGASGIGEALVKALAQQGCA-VSFFDIDEEAGEQLAQNLNS-HGMKAHFELVDLTD 77

Query: 194 EEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLKAI 355
            E     + A ++  G I  ++NNAA      L   S   + + + VN+     +  K  
Sbjct: 78  IEMLKDKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAVNLKHHFFAAQKVA 137

Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
            +M +     GG++IN+SS + +      P Y   K+ +   +  + R      T VRV 
Sbjct: 138 PLMAE---AGGGSIINMSSNSWMLGLSGYPGYVTAKAGISGLTKALAR--ELGPTKVRVN 192

Query: 536 TVCFG 550
           TV  G
Sbjct: 193 TVLPG 197


>UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1;
           Marinobacter sp. ELB17|Rep: Short chain dehydrogenase -
           Marinobacter sp. ELB17
          Length = 273

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 49/183 (26%), Positives = 94/183 (51%), Gaps = 6/183 (3%)
 Frame = +2

Query: 14  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193
           VFITG A+G+G ++      EG K + I D+  + G  ++ E+ SK G +  +   DV  
Sbjct: 5   VFITGGASGLGRAIALRYAREGAK-VCIGDVNPQQGALVEQEI-SKAGGEGYYVDCDVRR 62

Query: 194 EEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLKAI 355
            +    + + +    GG+D+V+NNA      ++ +  +  ++  +++NV  ++    KA 
Sbjct: 63  LKDLERVRDDLAARWGGVDIVVNNAGVASAGSIEDTPMADWEWILDINVLGVVRG-CKAF 121

Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
             M K  G   GT +N++S+A L  + +M  Y  +K+ V+  S  +   +   ++G++V 
Sbjct: 122 TPMFKQQG--AGTFVNIASMAGLMLAPMMNSYNVSKAGVIALSETMS--QELRESGIQVS 177

Query: 536 TVC 544
            VC
Sbjct: 178 CVC 180


>UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 286

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 57/207 (27%), Positives = 103/207 (49%), Gaps = 11/207 (5%)
 Frame = +2

Query: 11  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 190
           V  +TGAA GIG +  + L  +G++ +A+LD+  +A ++   EL S +         DVT
Sbjct: 21  VAIVTGAADGIGWATAQRLAADGLR-VALLDLRADAAQARAAELGSIHLG----LGCDVT 75

Query: 191 NEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNV--TALITST 343
           +EE     + AV++  G ID ++NNA +          S+  + + + V++  T L++  
Sbjct: 76  SEESVEAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHLRGTFLMSRA 135

Query: 344 LKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
           +    +      G+G G ++N+ S+A+ T       Y A K+ VL  +  +     +++ 
Sbjct: 136 VARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMA--SEWARA 193

Query: 521 GVRVLTVCFGATDTALLTD-EKLGTFD 598
           G+RV  V  G   TAL+ + E+ G  D
Sbjct: 194 GIRVNAVAPGYVRTALVAELERKGAID 220


>UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Paracoccus
           denitrificans (strain Pd 1222)
          Length = 253

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 51/190 (26%), Positives = 90/190 (47%), Gaps = 7/190 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDKVV ITGA  GIG +  ++ ++EG + + + D   +A + +  EL    G   + +  
Sbjct: 6   KDKVVLITGAGAGIGAATAKLFIEEGAR-VVVADYLGDAAEQVAAEL----GENARAFTV 60

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITST 343
           DV+  E    +++  V E GG+DV++NNA       +       ++  I+VN+T +   +
Sbjct: 61  DVSKAEACKAMVDFTVAEFGGLDVLVNNAGRGSLGTVETQDENDWRSIIDVNLTGVYLCS 120

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQS-HVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
             A+  + K     GG ++N +S  A+  +      Y A K  V   +  +     F+  
Sbjct: 121 KYAVPELRKRG---GGAIVNTASNIAMAMAIRDRAAYVAAKGGVASLTRAMAL--DFAAD 175

Query: 521 GVRVLTVCFG 550
            +RV +V  G
Sbjct: 176 NIRVNSVAPG 185


>UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=7; Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella sp. (strain
           ANA-3)
          Length = 253

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 59/206 (28%), Positives = 96/206 (46%), Gaps = 8/206 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +K   +TGAA GIG++++R LL EG + +A    A+ +  +L+V  N    +K   +  D
Sbjct: 5   NKTAVVTGAAGGIGQAIIRKLLAEGARVVA----ADLSADALKV-FNDFPADKLVTFSVD 59

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITST 343
           VT+ +    ++     + G +D++INNA        L +D I  ++    VN   +    
Sbjct: 60  VTDYKQVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQKGVYHGI 119

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
           L         + G  G ++N SSV A   S +   Y  +K+AV   + C       +  G
Sbjct: 120 LAGGRQF--QAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAAL--ELAPLG 175

Query: 524 VRVLTVCFGATDTALLTD-EKLGTFD 598
           VRV  V  G  DT +L   E LG ++
Sbjct: 176 VRVCAVAPGRVDTPMLRQYEALGLWE 201


>UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=2;
           Bacillus|Rep: Uncharacterized oxidoreductase yqjQ -
           Bacillus subtilis
          Length = 259

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 62/214 (28%), Positives = 105/214 (49%), Gaps = 7/214 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K ++ITGA+ G+GE +  +   EG  H+ +    E+    ++ ++  ++  + + +  DV
Sbjct: 7   KRIWITGASGGLGERIAYLCAAEGA-HVLLSARREDRLIEIKRKITEEWSGQCEIFPLDV 65

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 349
              E    + + +    G IDV+INNA       +++ ++   K   +VNV  LI  T  
Sbjct: 66  GRLEDIARVRDQI----GSIDVLINNAGFGIFETVLDSTLDDMKAMFDVNVFGLIACTKA 121

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            +  M +    K G +IN++S A    +    +Y ATK AVL +SN + R E  S TG+ 
Sbjct: 122 VLPQMLEQ---KKGHIINIASQAGKIATPKSSLYSATKHAVLGYSNAL-RME-LSGTGIY 176

Query: 530 VLTVCFGATDTALLT-DEKLGTFDKYLEFFMLGP 628
           V TV  G   T   +  +K G + K +  +ML P
Sbjct: 177 VTTVNPGPIQTDFFSIADKGGDYAKNVGRWMLDP 210


>UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3;
           Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 -
           Eubacterium sp. (strain VPI 12708)
          Length = 249

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 49/194 (25%), Positives = 92/194 (47%), Gaps = 7/194 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 178
           +DK+  ITG   GIG +  ++ ++ G K ++I    +E   +   +L   Y  +    + 
Sbjct: 5   QDKITIITGGTRGIGFAAAKLFIENGAK-VSIFGETQEEVDTALAQLKELYPEEEVLGFA 63

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 340
            D+T+ +  +  +  V Q+ G +DV+INNA +  +S+        +K  +++NV  +   
Sbjct: 64  PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
              A + M      K G +IN +SV  +  S     Y  +K+ V+  ++ +GR     + 
Sbjct: 124 AWSAYQCM---KDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGR--EIIRK 178

Query: 521 GVRVLTVCFGATDT 562
            +RV+ V  G  DT
Sbjct: 179 NIRVVGVAPGVVDT 192


>UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41;
           Magnoliophyta|Rep: Xanthoxin dehydrogenase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 285

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 58/196 (29%), Positives = 90/196 (45%), Gaps = 9/196 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY-RSD 184
           KV  ITG ATGIGES+VR+    G K + I+D+ ++ G  +   L      +T F+   D
Sbjct: 21  KVALITGGATGIGESIVRLFHKHGAK-VCIVDLQDDLGGEVCKSLLRGESKETAFFIHGD 79

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL--------MNDSIGIYKKAIEVNVTALITS 340
           V  E+     ++  V+  G +D++INNA L         N S+  ++   +VNV     S
Sbjct: 80  VRVEDDISNAVDFAVKNFGTLDILINNAGLCGAPCPDIRNYSLSEFEMTFDVNVKGAFLS 139

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
              A  +M      K G+++++ SV  +        Y  +K AVL  +  V       + 
Sbjct: 140 MKHAARVMIPE---KKGSIVSLCSVGGVVGGVGPHSYVGSKHAVLGLTRSVA--AELGQH 194

Query: 521 GVRVLTVCFGATDTAL 568
           G+RV  V   A  T L
Sbjct: 195 GIRVNCVSPYAVATKL 210


>UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus
           iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis
          Length = 267

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 59/217 (27%), Positives = 110/217 (50%), Gaps = 7/217 (3%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +K + ITGA++GIGE + + +  +G   I +    ++   ++Q E++  Y  ++  Y  D
Sbjct: 9   NKKIIITGASSGIGEMLAKKVASQGGFPILVARSRDKL-ITIQKEIDQLYNQRSAIYPID 67

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGIYK-----KAIEVNVTALITSTL 346
           +T++++   ++ A++ +   ID +INNA L + DSI         +  ++NV A I  + 
Sbjct: 68  LTDKDNIDNLIPAIINDNKQIDALINNAGLGVFDSIEDMNYDDLLETFQLNVFAGIQLSQ 127

Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
             I  + K +      ++NV S AA   +     Y ++K A+L F+N V R E    + +
Sbjct: 128 SIIPYLRKTNANT--QIVNVISQAAKISTPKSASYASSKQAMLGFTN-VLRME-CRMSSI 183

Query: 527 RVLTVCFGATDTALL-TDEKLGTFDKYLEFFMLGPTK 634
            V+ V  G   T      +K GT+ + +E +ML P +
Sbjct: 184 HVMAVNLGPVRTNFFERADKDGTYKQNVEKYMLDPER 220


>UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductase;
           n=4; Bacteria|Rep: Short-chain
           dehydrogenase/oxidoreductase - Lactobacillus plantarum
          Length = 279

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 8/168 (4%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           DKVV ITGA  G+G         +G K I ++D+  +  ++   +L  KYG +T   + +
Sbjct: 10  DKVVAITGAVGGMGTKFCEEFAKQGAK-IVLIDMIADKTEAYAKKLTEKYGVETLAVKCN 68

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTA--LITS 340
            TNEE     + AV  + G +DV++N AA++  S      +  ++ A+ VN+T   L++ 
Sbjct: 69  TTNEEEVDAAVKAVTDKFGEVDVLVNTAAILRFSPLEDLRLDEWQAALNVNLTGYFLMSQ 128

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 484
               + I  KH     G ++++S+VA+         Y  TK+AV   S
Sbjct: 129 RFGRVMIQQKH-----GAMVHISTVASRYPETYSGAYSTTKAAVNMMS 171


>UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Mesorhizobium sp. BNC1|Rep: Short-chain
           dehydrogenase/reductase SDR - Mesorhizobium sp. (strain
           BNC1)
          Length = 260

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 57/197 (28%), Positives = 93/197 (47%), Gaps = 8/197 (4%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +K+ FITGAA GIG     +   EG K + + DI E+ G+ +  ++ S  G    F R D
Sbjct: 5   NKIAFITGAAEGIGACAAGLFSREGAK-VILSDIDEDRGRKVADQVTSA-GGDAVFVRCD 62

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTALITS 340
           VT+E        AV +  G + ++ NN          + +  +  +  A+++NV +++  
Sbjct: 63  VTSEASVREAAAAVQERYGALHILYNNVGGSTPRDDRVTDVDLEEFWSAMKLNVLSVVLP 122

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               I ++   SG  GG+VIN +S  AL  +     Y A+K AV+  +  +     F   
Sbjct: 123 ARHLIPLIAA-SG--GGSVINTASYMALLGTAGRDCYTASKGAVVSLTRSMA--VEFGPD 177

Query: 521 GVRVLTVCFGATDTALL 571
            +RV  +  GA DT  L
Sbjct: 178 NIRVNVIGPGAVDTERL 194


>UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Enterobacter sp. 638|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Enterobacter sp.
           638
          Length = 242

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 56/195 (28%), Positives = 97/195 (49%), Gaps = 6/195 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K +V  +TGA++GIGE++ R L   G++ + +    E     + V L S+ G+     ++
Sbjct: 6   KKRVAVVTGASSGIGEALARELAGNGIQVVLLARRFER----IDV-LASELGHGAIAIKA 60

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 343
           DVT+ E  +   N V Q  GG+D++INNA +M      +  +  +++ +E N+   +T T
Sbjct: 61  DVTDRESIVAAANQVEQTLGGVDILINNAGVMLTGPFDSSQLDEHRQMVETNLLGAMTVT 120

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
               E+         G ++N+SSVA         +Y ATK  +  +S  + R E   +  
Sbjct: 121 ----EVFLPQLRRNKGDLVNISSVAGRVAPSGFAVYAATKWGINGWSEAL-RVE--LQPD 173

Query: 524 VRVLTVCFGATDTAL 568
           +RV+ +  GA  T L
Sbjct: 174 IRVMVIEPGAIATEL 188


>UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1;
           Alteromonas macleodii 'Deep ecotype'|Rep: Short chain
           dehydrogenase - Alteromonas macleodii 'Deep ecotype'
          Length = 276

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 52/168 (30%), Positives = 83/168 (49%), Gaps = 11/168 (6%)
 Frame = +2

Query: 14  VFITGAATGIGESVVRILLD-----EGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 178
           V ITG ATG+G+++     +     EG   I I DI +E G      L ++ G K  +  
Sbjct: 3   VLITGGATGLGQAIAFKWAEKWKGKEGGIEICIADINQERGDETVNTLTTQ-GAKAFYVY 61

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITS 340
            D+T++     +   +    GGID V NNA      +L++++I  ++   ++NV  ++  
Sbjct: 62  CDITSDSDVETLAQTIEARWGGIDTVFNNAGVATGGSLLDETIDQWQWVFDINVLGMVRV 121

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 484
           +   + IM K     GG  IN++S A LT    M  Y A K+AV+ FS
Sbjct: 122 SRALLPIMRKQG---GGYFINIASQAGLTPIPYMGSYNAVKAAVVSFS 166


>UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=1; Flavobacteriales bacterium HTCC2170|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase -
           Flavobacteriales bacterium HTCC2170
          Length = 245

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 52/196 (26%), Positives = 93/196 (47%), Gaps = 6/196 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDK+  +TG A GIG++V  +   EG   + I+D+  + G+++   + +  G K +++  
Sbjct: 4   KDKIAVVTGGARGIGQAVSELFAKEGAT-VIIMDLLPQ-GQAVAEGIIAS-GGKAEYHSL 60

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 343
            VTN+    G+ ++V  + G ID++INNA +  D      S   +   IEVN+  +   T
Sbjct: 61  SVTNKSDVEGVFSSVNDKYGKIDILINNAGITRDRTLEKMSEAEWDAVIEVNLKGVFICT 120

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
              +  M      K G +++ +S   L  +     Y ATK+ V+  +        F K G
Sbjct: 121 QAVVPYM---KASKYGRIVSAASNVGLRGNFGQTNYAATKAGVIAMAKT--WTVEFGKYG 175

Query: 524 VRVLTVCFGATDTALL 571
           +    +  G T T ++
Sbjct: 176 ITANAIAPGFTMTDMV 191


>UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=3;
           Bacteroidetes|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Polaribacter
           dokdonensis MED152
          Length = 257

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 62/223 (27%), Positives = 111/223 (49%), Gaps = 13/223 (5%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITG++ GIG+++ + L ++G + + I    +EA   +  E   + G  T      +
Sbjct: 12  KVAVITGSSKGIGKAIAKGLAEQGAQ-VVISSRNQEACDEVAKEFKEQ-GLDTIGIACHI 69

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG--------IYKKAIEVNVTALITST 343
             E+    +++  ++  G ID+++NNAA+ N   G        I+ K ++VNV A    +
Sbjct: 70  GKEDQRKNLVDKTIESFGRIDILVNNAAI-NPVFGPIEEVSPEIFDKIMDVNVKA--PWS 126

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
           L  + ++      K G++IN++SV ALT    + IY  +K+A+L  +    + + + K G
Sbjct: 127 LSNL-VLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTK--NQAKEWGKYG 183

Query: 524 VRVLTVCFGATDT----ALLTDEK-LGTFDKYLEFFMLGPTKE 637
           V+   +C G   T    AL  +EK L   +K L    +G  +E
Sbjct: 184 VKANAICPGLIKTKFSAALWQNEKILSKVEKALPSSRMGMPEE 226


>UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductase
           precursor; n=8; Plasmodium|Rep: 3-oxoacyl-acyl-carrier
           protein reductase precursor - Plasmodium falciparum
          Length = 301

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 42/169 (24%), Positives = 88/169 (52%), Gaps = 3/169 (1%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           ++KV  +TGA  GIG  + + +L + V H+  +   +++  S+  E+ S +G ++  Y  
Sbjct: 59  ENKVALVTGAGRGIGREIAK-MLAKSVSHVICISRTQKSCDSVVDEIKS-FGYESSGYAG 116

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE---VNVTALITSTLKA 352
           DV+ +E    ++N ++ E   +D++++NA +  D++ +  K  E   V  T L +     
Sbjct: 117 DVSKKEEISEVINKILTEHKNVDILVSNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYIT 176

Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499
             I  +    + G +IN+SS+  LT +     Y ++K+ V+ F+  + +
Sbjct: 177 QPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAK 225


>UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59;
           cellular organisms|Rep: Acetoin(diacetyl) reductase -
           Klebsiella pneumoniae
          Length = 256

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 53/193 (27%), Positives = 88/193 (45%), Gaps = 6/193 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGA  GIG+++   L+ +G   +AI D  +   K++  E+N   G +    + DV
Sbjct: 3   KVALVTGAGQGIGKAIALRLVKDGFA-VAIADYNDATAKAVASEINQA-GGRAMAVKVDV 60

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN----DSI--GIYKKAIEVNVTALITSTLK 349
           ++ +     +    +  GG DV++NNA +      +SI   I  K   +NV  +I     
Sbjct: 61  SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
           A+E   K   G GG +IN  S A    +  + +Y ++K AV   +    R    +  G+ 
Sbjct: 121 AVEAFKKE--GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR--DLAPLGIT 176

Query: 530 VLTVCFGATDTAL 568
           V   C G   T +
Sbjct: 177 VNGYCPGIVKTPM 189


>UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein)
           reductase, putative; n=10; Bacillus cereus group|Rep:
           3-oxoacyl-(Acyl-carrier-protein) reductase, putative -
           Bacillus anthracis
          Length = 246

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 50/192 (26%), Positives = 94/192 (48%), Gaps = 7/192 (3%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K   +TGAA GIG+ + R+    G K + I D+ EE  +    EL  + G +   YR DV
Sbjct: 7   KTAVVTGAAQGIGKEIARVYAKLGAK-VLISDVNEEKLQKTTRELLDE-GYEVSLYRCDV 64

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 349
           +N+     ++   VQ+ G + +++NNA +  D++        +++ ++VN+T +      
Sbjct: 65  SNQNEAKSLIEYAVQKFGTLHILVNNAGITRDAMLHKMEKSSWEQVLQVNLTGVFYCMQP 124

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
           A+  M +   G+   +IN+SS++   + ++    Y ATK+ V+  +    +       G+
Sbjct: 125 ALLYMRQQGYGR---IINISSIS--REGNIGQANYAATKAGVVGLTKTAAK--EVGSFGI 177

Query: 527 RVLTVCFGATDT 562
               +C G  DT
Sbjct: 178 TCNAICPGFMDT 189


>UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia
           succiniciproducens MBEL55E|Rep: FabG protein -
           Mannheimia succiniciproducens (strain MBEL55E)
          Length = 248

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 54/195 (27%), Positives = 93/195 (47%), Gaps = 6/195 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           + K   +TGA TGIG+++   L  EG K +    +     K+LQ E  + + N   +  +
Sbjct: 5   EQKTALVTGAGTGIGQAIAVRLAQEGAKVL----VVGRTEKTLQ-ETTALHPN-IAYAVA 58

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 343
           D+  ++    I+  + Q+ GG+D++INNA       +    I  Y K   +NV AL+  T
Sbjct: 59  DIEKDDDVQKIVQQLNQKYGGLDILINNAGWAPVTPISQVKIEEYDKVFGINVRALVNLT 118

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
           L+ + ++      + G +IN+SS         M +Y  TK+AV  F+    +       G
Sbjct: 119 LQCLPML----KARKGNIINMSSAICRNHLPNMSMYAGTKAAVEIFTKIWAK--ELGADG 172

Query: 524 VRVLTVCFGATDTAL 568
           VRV ++  G  +T +
Sbjct: 173 VRVNSISVGPIETPI 187


>UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep:
           Oxidoreductase - Geobacillus kaustophilus
          Length = 260

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 62/218 (28%), Positives = 106/218 (48%), Gaps = 12/218 (5%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K   +TG   G+GE +   L + G  ++ +     EA + ++ +L  + G ++   R DV
Sbjct: 12  KTAIVTGGGRGLGEQIAVGLAEAGA-NVVVCSRKVEACEQVKEKLE-QLGVRSLALRCDV 69

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINN------AALMNDSIGIYKKAIEVNVTALITSTLK 349
           TN E    ++   V+E GGID+++NN      A +    +  ++K I VNVT     +  
Sbjct: 70  TNPEEVKHVVETTVKEFGGIDILVNNSGATWGAPVEEMPLEAWQKVINVNVTGTFLMSQA 129

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPI----YFATKSAVLQFSNCVGRPEHFSK 517
             ++M   +   GG++IN++SVA L  +H   +    Y  +K AV+ F+  +     + K
Sbjct: 130 VGKVM--IAKQTGGSIINIASVAGLGGTHPDILNTIGYNTSKGAVITFTRDLA--AKWGK 185

Query: 518 TGVRVLTVC--FGATDTALLTDEKLGTFDKYLEFFMLG 625
            G+RV  V   F  T  + +  E++G   K LE   LG
Sbjct: 186 HGIRVNAVAPGFFPTKMSKVVLERVG--KKVLEHTPLG 221


>UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Geobacter|Rep: Short-chain dehydrogenase/reductase
           SDR - Geobacter metallireducens (strain GS-15 / ATCC
           53774 / DSM 7210)
          Length = 255

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 54/193 (27%), Positives = 91/193 (47%), Gaps = 9/193 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  ITG A GIG +    L  EG K I I D+ + A     VE     G+   + ++DV
Sbjct: 7   KVAIITGGAQGIGAAYAVGLAKEGAK-IVIADVLDGAKA---VEAVKAAGSDAIYVKTDV 62

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTALITS 340
           +++E    +  A  ++ G +D+++NNAA+    +           + K +E+NV     +
Sbjct: 63  SSQEQCDAMAQAAAEKFGSVDILLNNAAIFGSIVLKPFTECTPQEFMKVMEINVLGQF-N 121

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
            +KA+     H   +GG +IN+SS + +     MP Y A+K A++  +  + R     K 
Sbjct: 122 CMKAV---FPHMKARGGKIINISSSSIIEGVPGMPHYVASKGAIMALTRSMARELGDYKI 178

Query: 521 GVRVLTVCFGATD 559
            V  +   F  +D
Sbjct: 179 NVNTIAPGFTHSD 191


>UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1;
           Marinobacter algicola DG893|Rep: Short chain
           dehydrogenase - Marinobacter algicola DG893
          Length = 252

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 53/166 (31%), Positives = 83/166 (50%), Gaps = 7/166 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           KV  +TGA   IGE V R+L  EG   IA++D+     + +  ++ +  G + K +  DV
Sbjct: 6   KVAIVTGAGRNIGEEVSRVLSAEGAT-IAVVDLDRSRAEKVAADIVAS-GGQAKPFICDV 63

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-KAIEVNVTALITSTLK----- 349
            +E+     + AVV + GG+D+++NN A M+D+  I+   A E N T  IT T       
Sbjct: 64  ASEDQIRATVAAVVDQLGGLDILVNNVA-MSDNKHIFDITAEEWNRTLAITLTAPFLFGK 122

Query: 350 -AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 484
            A + M +H+    G +INVSS +          Y A K  V+  +
Sbjct: 123 YAAQAMVQHAA--DGRIINVSSTSGYYGRDRAIAYTAAKGGVINLT 166


>UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Psychrobacter sp. PRwf-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
          Length = 273

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 58/198 (29%), Positives = 96/198 (48%), Gaps = 10/198 (5%)
 Frame = +2

Query: 20  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY---GNKTKFYRSDVT 190
           +TGAA+GIG ++   LL +    +   DI  EA    Q+  N K    G      + DV 
Sbjct: 7   VTGAASGIGRALCERLLTDKGNQVCACDINYEA--LTQIYANHKLADAGGSLILRQLDVR 64

Query: 191 NEEHFLGILNAVVQEQGGIDVVINNAALMNDS----IGIYKKA---IEVNVTALITSTLK 349
           + + +  ++N V+ +   IDV+ N A ++ D+    I +        ++NV   I  T  
Sbjct: 65  DVQQWQEVVNTVIAQWQRIDVMCNIAGVLKDNWIADIALPDDVDLHFDINVKGTIFGTQS 124

Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529
            ++ M ++ G   G +INV+S+AAL+    + +Y A+K AV  +S   G      K G+ 
Sbjct: 125 VVDTM-RNQGS--GHIINVASLAALSPVPGLSLYSASKYAVRAYSLAAGM--ELEKYGIA 179

Query: 530 VLTVCFGATDTALLTDEK 583
           V T+C  A  T +L  +K
Sbjct: 180 VTTLCPDAVQTPMLDQQK 197


>UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Stappia aggregata IAM 12614|Rep: Short-chain
           dehydrogenase/reductase SDR - Stappia aggregata IAM
           12614
          Length = 270

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 8/200 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           +V  +TGA+ GIGE+  R L   G K + +   +++  + +  E+ ++ G        DV
Sbjct: 24  QVALVTGASRGIGEAAARSLAKYGAK-VVLAARSDKDIERIAGEIRAE-GQDATAVVCDV 81

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346
            + +  +  +   V   GG+D+++NNA ++     I       + K I++NV  +     
Sbjct: 82  ADYDDVVKAVQTAVDTYGGLDILVNNAGVIEPIARIEDSDPAEWGKVIDINVKGVYYG-- 139

Query: 347 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             +    KH   KG GTV+N+SS AA++       Y A+K+A L  + C  +   F   G
Sbjct: 140 --LHAAAKHMLAKGAGTVVNISSGAAVSALEGWSHYCASKAAALSLTRCADK--EFGDKG 195

Query: 524 VRVLTVCFGATDTALLTDEK 583
           +R++ +  G   T +  D K
Sbjct: 196 LRIVGLSPGTVATQMQVDIK 215


>UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella woodyi ATCC
           51908
          Length = 255

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 49/191 (25%), Positives = 94/191 (49%), Gaps = 6/191 (3%)
 Frame = +2

Query: 14  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193
           VFITG A+GIG ++VR  +++G  ++  +D   +AG++L   L+   G +  F+  DVT+
Sbjct: 15  VFITGGASGIGAALVRAFVEQGA-NVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTD 73

Query: 194 EEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGI----YKKAIEVNVTALITSTLKAI 355
            +    ++    Q+ G +D++INN      +D+ G+    +K+ + +N+ +   ++  A 
Sbjct: 74  TKQLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAY 133

Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535
            +M +    K G +IN SS  A      M  Y   K+ +   +  + +    S+  V  +
Sbjct: 134 LVMKQR---KQGVIINFSSNMAYIGERNMAGYITAKAGIAGMTKALAKDYGESRVRVNAI 190

Query: 536 TVCFGATDTAL 568
              + AT   L
Sbjct: 191 VPGWVATQRQL 201


>UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep:
           PksB - Dictyostelium discoideum (Slime mold)
          Length = 260

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 61/205 (29%), Positives = 100/205 (48%), Gaps = 6/205 (2%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVEL-NSKYGNKTKFYRS 181
           +K+V ITGA++GIGES  +I    G  HI +     +    L+ +L  +  G K    + 
Sbjct: 7   NKIVLITGASSGIGESCAKIFHQNG-NHIILCGRRVDRLNKLRDQLIANNSGGKVLACQV 65

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI-- 355
           DV++ E    ++N + ++   ID++INNA L      + +   + ++ ++I + +K +  
Sbjct: 66  DVSSMESIDKMINELPEDMKSIDILINNAGLSLGMDSVSEIDAKNDLDSVIDTNVKGVFR 125

Query: 356 ---EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526
              +I+        G + NVSS+A         IY A+K+AV  FS+ V R E  S T +
Sbjct: 126 VTRKILPNMIQRNSGYIFNVSSIAGSMFYPNGSIYCASKAAVNAFSD-VLRKEVVS-TKI 183

Query: 527 RVLTVCFGATDTALLTDEKLGTFDK 601
           RV  VC G  +T        G  DK
Sbjct: 184 RVTNVCPGLVETEFSLVRFNGDADK 208


>UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;
           n=30; Bacteria|Rep: Uncharacterized oxidoreductase
           Lin0452 - Listeria innocua
          Length = 248

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 55/193 (28%), Positives = 89/193 (46%), Gaps = 3/193 (1%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K+KV+ ITGA++GIGE+   +L ++G K +      E+  K +Q  + +  G +  F ++
Sbjct: 4   KNKVIIITGASSGIGEATAILLAEKGAKLVLAARRVEKLEKIVQT-IKASSG-EAIFAKT 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM-NDSIGIYKK-AIEVNVTALITSTLKAI 355
           DVT  E    ++   ++  G +D +  NA +M N  +   K+   E  +   I   L  I
Sbjct: 62  DVTKREDNKKLVELAIERYGKVDAIFLNAGIMPNSPLSALKEDEWEQMIDINIKGVLNGI 121

Query: 356 -EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532
             ++      K G +I  SSVA L       +Y ATK AV      +        T +R 
Sbjct: 122 AAVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEGTNIRT 181

Query: 533 LTVCFGATDTALL 571
            T+   A +T LL
Sbjct: 182 ATIYPAAINTELL 194


>UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2;
           Streptomyces|Rep: Putative dehydrogenase - Streptomyces
           coelicolor
          Length = 255

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 8/195 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187
           K   +TGA +GIG +V   L  EG  H+ +   A          L  + G K     +DV
Sbjct: 9   KTALVTGAGSGIGRAVALALAAEGA-HVVVAGRAR-GPLDETAALVEQAGGKALAVTADV 66

Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346
           T  E    +++A V+  G +DV +NNA +    + +       +   +++NVT +  +  
Sbjct: 67  TRREDVDALVSAAVEHFGSLDVAVNNAGVFRGGVPVADLSEEDWHTQLDINVTGVFLALR 126

Query: 347 KAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             +  M    G  GGT++N++S   A  +S     Y ATK+AV   +      +H    G
Sbjct: 127 AEVRHMRAQPG--GGTIVNIASTFGAHKRSPGATAYAATKAAVSALTRGAAL-DHIG-DG 182

Query: 524 VRVLTVCFGATDTAL 568
           VR+  V  GAT T++
Sbjct: 183 VRINAVSPGATATSM 197


>UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep:
           Bll5898 protein - Bradyrhizobium japonicum
          Length = 256

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 60/196 (30%), Positives = 90/196 (45%), Gaps = 7/196 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR- 178
           KDKVV +TGA +GIG +  R    EG   I +L+   E   S   E+ ++ G      R 
Sbjct: 6   KDKVVIVTGAGSGIGAAAARRFHGEGA--IVVLNGRRE---SKLAEVGAELGTDRCMIRP 60

Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 340
           +DVT       ++   V+  G ID+++NNA        +   I  ++    VNV  ++  
Sbjct: 61  ADVTIAADVESLVADAVRRFGRIDILVNNAGTGALIDFLGSPIQQWRDLFAVNVDGVLYM 120

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
           T  A+     H    GG+++NVSS++ L     +  Y ATK AV   +  +     F   
Sbjct: 121 TRAAL----PHLIESGGSIVNVSSLSGLGGDRGLSFYNATKGAVSNLTRSLAL--EFGPR 174

Query: 521 GVRVLTVCFGATDTAL 568
           GVR+  VC   T T L
Sbjct: 175 GVRINAVCPSLTLTHL 190


>UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase,
           putative; n=25; Alphaproteobacteria|Rep:
           20-beta-hydroxysteroid dehydrogenase, putative -
           Silicibacter pomeroyi
          Length = 250

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 57/202 (28%), Positives = 93/202 (46%), Gaps = 8/202 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           K K V ITGA+ GIG    R+    G  ++ +L  + EA  +   E+    G++      
Sbjct: 5   KGKTVLITGASRGIGAEAGRVFAQAGA-NVVLLARSAEALAAQAAEI----GDRALALAC 59

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM--------NDSIGIYKKAIEVNVTALIT 337
           DV +     G +NA V   GG+DV+INNA ++        +D +G +  AI++N+  +  
Sbjct: 60  DVADAAQVAGAVNAAVSRFGGLDVLINNAGVIEPISHLASSDPVG-WGHAIDINLKGVYY 118

Query: 338 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517
               A+ +M K     GGT++ VSS AA         Y A+K+     + C+   E    
Sbjct: 119 GMRAALPVMRK---AGGGTILTVSSGAAHNPVEAWSHYCASKAGAAMLTACLHLEE--GH 173

Query: 518 TGVRVLTVCFGATDTALLTDEK 583
            G+R + +  G   T +  + K
Sbjct: 174 HGIRAMGLSPGTVATQMQREIK 195


>UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=3; Cyanobacteria|Rep: NAD-dependent
           epimerase/dehydratase precursor - Anabaena variabilis
           (strain ATCC 29413 / PCC 7937)
          Length = 251

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 51/194 (26%), Positives = 90/194 (46%), Gaps = 7/194 (3%)
 Frame = +2

Query: 2   KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181
           KDKV  +TG  +GIG +       +  K + +    +E  ++  V L  + G +  F +S
Sbjct: 4   KDKVALVTGGTSGIGRATAIAYAKQQAKVVVVGRRIDEGEET--VRLIQEAGGEAFFVQS 61

Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 340
           DVT E     +++  V   G +D+  NNA ++ ++  +       Y + + VNV  +  S
Sbjct: 62  DVTKEADVKAMVDKAVGVFGRLDIAFNNAGMVGENPSLIEQTEAEYDRIMNVNVKGVWLS 121

Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520
               I  M K      G ++N SS A +     +P+Y A+K AV+  +        ++K 
Sbjct: 122 MKYEIAQMLKQG---SGAIVNTSSGAGVVALPGVPLYTASKHAVVGLTKAAAL--QYAKA 176

Query: 521 GVRVLTVCFGATDT 562
           G+R+  V  G+ +T
Sbjct: 177 GIRINAVAPGSIET 190


>UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 306

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 8/193 (4%)
 Frame = +2

Query: 8   KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSK-YGNKTKFYRSD 184
           KV  ITGA +GIG S   +   EG + +     A+ +G+     L +K  G+       D
Sbjct: 67  KVAVITGAGSGIGRSAAFLFAREGARVVC----ADVSGREA---LTAKAVGDGAIAVHVD 119

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITST 343
           VT+ E    ++   V   G +DV+ NNA      + +       +   + VNV  +    
Sbjct: 120 VTSTEDIERMITTAVDRFGKLDVLYNNAGFTGPIVPLAEAGEDYFDAVMAVNVKGVYLGM 179

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523
             AI +M     G GG++IN +S A L     + +Y ATK AV+Q +        ++  G
Sbjct: 180 KAAIPVM---LAGGGGSIINTASAAGLVGWKGLAVYAATKGAVVQLTRSAAL--DYAAKG 234

Query: 524 VRVLTVCFGATDT 562
           +RV  VC GAT T
Sbjct: 235 IRVNAVCPGATWT 247


>UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=1; Pedobacter sp. BAL39|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Pedobacter
           sp. BAL39
          Length = 248

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 9/198 (4%)
 Frame = +2

Query: 5   DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184
           +KV  ITGAA G+GES  R  + EG K + + D++ EAG+ L  EL    G    F + D
Sbjct: 6   NKVAIITGAAQGMGESHARTFVAEGAK-VILTDVSAEAGQKLADEL----GENAIFIKHD 60

Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITST 343
           VT  E +  ++    +  G ++V++NNA ++   +         Y K  ++N  ++    
Sbjct: 61  VTCSEQWAHVVAEAEKAFGHVNVLVNNAGILGPMVKTQELQEADYLKVCDINQHSVFYGM 120

Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCVGRPEHFSK 517
              I  M K      G+++N+SS+A +  ++  P   Y A+K AV   +        + +
Sbjct: 121 KAVIPSMIK---AGIGSIVNISSIAGIVANYGFPSLAYVASKFAVRGMTKATA--IEYGE 175

Query: 518 TGVRVLTVCFGATDTALL 571
             +RV +V  G   T ++
Sbjct: 176 KNIRVNSVHPGFIKTPMM 193


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 618,708,219
Number of Sequences: 1657284
Number of extensions: 12277825
Number of successful extensions: 43153
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 39075
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40684
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 47711253245
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -