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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= heS00023
         (608 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog...   116   3e-25
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA...   113   3e-24
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5...   105   6e-22
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7...   104   2e-21
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...   102   8e-21
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5...   101   1e-20
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve...    99   7e-20
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3...    96   7e-19
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4...    95   9e-19
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3...    95   1e-18
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    95   1e-18
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    95   2e-18
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    94   2e-18
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    93   5e-18
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8...    93   5e-18
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    91   1e-17
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5...    91   1e-17
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy...    91   2e-17
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl...    90   3e-17
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl...    90   3e-17
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3...    90   4e-17
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4...    90   4e-17
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro...    89   6e-17
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    89   8e-17
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    88   1e-16
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph...    87   2e-16
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos...    87   3e-16
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    86   5e-16
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al...    85   9e-16
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    85   9e-16
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5...    85   1e-15
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    85   1e-15
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    84   3e-15
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl...    84   3e-15
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    83   4e-15
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl...    83   4e-15
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela...    83   5e-15
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    83   5e-15
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba...    83   7e-15
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3...    83   7e-15
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro...    81   2e-14
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3...    81   3e-14
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba...    80   4e-14
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase...    80   5e-14
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd...    80   5e-14
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha...    79   6e-14
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7...    79   8e-14
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro...    79   8e-14
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom...    79   1e-13
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5...    78   2e-13
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc...    77   2e-13
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    77   2e-13
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    77   3e-13
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa...    76   8e-13
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    75   1e-12
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro...    74   2e-12
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    74   2e-12
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4...    73   4e-12
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ...    73   5e-12
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    73   7e-12
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro...    73   7e-12
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3...    72   1e-11
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3...    71   2e-11
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro...    71   2e-11
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant...    71   3e-11
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    71   3e-11
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro...    70   4e-11
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    70   4e-11
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge...    69   7e-11
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    69   1e-10
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro...    68   2e-10
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ...    68   2e-10
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    68   2e-10
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro...    68   2e-10
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2...    67   3e-10
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    67   4e-10
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    66   5e-10
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ...    66   5e-10
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro...    66   6e-10
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro...    66   8e-10
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro...    65   1e-09
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    65   1e-09
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte...    65   1e-09
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21...    65   1e-09
UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6; ...    65   1e-09
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La...    64   2e-09
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE...    64   2e-09
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    64   2e-09
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4...    64   2e-09
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro...    64   3e-09
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n...    64   3e-09
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S...    64   3e-09
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella...    63   6e-09
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro...    63   6e-09
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    63   6e-09
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro...    63   6e-09
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p...    63   6e-09
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R...    62   8e-09
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr...    62   8e-09
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl...    62   8e-09
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh...    62   1e-08
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388...    62   1e-08
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro...    62   1e-08
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    62   1e-08
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    62   1e-08
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put...    61   2e-08
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro...    61   2e-08
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    61   2e-08
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    60   3e-08
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ...    60   4e-08
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro...    60   4e-08
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    60   4e-08
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    60   4e-08
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    60   4e-08
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n...    60   5e-08
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr...    60   5e-08
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro...    60   5e-08
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici...    60   5e-08
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro...    60   5e-08
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ...    60   5e-08
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ...    59   7e-08
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro...    59   7e-08
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro...    59   7e-08
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace...    58   1e-07
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro...    58   1e-07
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria...    58   2e-07
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu...    58   2e-07
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge...    58   2e-07
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe...    58   2e-07
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ...    58   2e-07
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd...    58   2e-07
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu...    58   2e-07
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5...    58   2e-07
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    58   2e-07
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge...    58   2e-07
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom...    58   2e-07
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or...    58   2e-07
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco...    57   3e-07
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro...    57   3e-07
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ...    57   3e-07
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th...    57   3e-07
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    57   4e-07
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    57   4e-07
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro...    57   4e-07
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ...    56   5e-07
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c...    56   5e-07
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    56   5e-07
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    56   5e-07
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ...    56   5e-07
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re...    56   5e-07
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba...    56   7e-07
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    56   7e-07
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro...    56   9e-07
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    56   9e-07
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put...    56   9e-07
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    56   9e-07
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh...    56   9e-07
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    56   9e-07
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc...    55   1e-06
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro...    55   1e-06
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    55   1e-06
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    55   1e-06
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase...    55   1e-06
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    55   1e-06
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n...    55   1e-06
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi...    55   1e-06
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n...    55   2e-06
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela...    55   2e-06
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ...    55   2e-06
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro...    55   2e-06
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro...    55   2e-06
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re...    55   2e-06
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put...    55   2e-06
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    55   2e-06
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re...    54   2e-06
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n...    54   2e-06
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro...    54   3e-06
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact...    54   3e-06
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro...    54   3e-06
UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid dehydro...    54   3e-06
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    54   3e-06
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot...    54   4e-06
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro...    54   4e-06
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n...    54   4e-06
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ...    54   4e-06
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    53   5e-06
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    53   5e-06
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci...    53   5e-06
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro...    53   5e-06
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa...    53   5e-06
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n...    53   5e-06
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n...    53   5e-06
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8...    53   6e-06
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro...    53   6e-06
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro...    53   6e-06
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit...    53   6e-06
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like...    53   6e-06
UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    52   8e-06
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro...    52   8e-06
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi...    52   8e-06
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ...    52   8e-06
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    52   8e-06
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro...    52   8e-06
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es...    52   1e-05
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro...    52   1e-05
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    52   1e-05
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro...    52   1e-05
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    52   1e-05
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=...    52   1e-05
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost...    52   1e-05
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo...    51   2e-05
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    51   2e-05
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555...    51   2e-05
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    51   2e-05
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    51   2e-05
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba...    51   2e-05
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro...    51   2e-05
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    51   2e-05
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse...    50   3e-05
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro...    50   3e-05
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ...    50   3e-05
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n...    50   3e-05
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    50   3e-05
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    50   3e-05
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    50   3e-05
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ...    50   4e-05
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2...    50   4e-05
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    50   4e-05
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro...    50   6e-05
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;...    50   6e-05
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu...    49   8e-05
UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1; Lacto...    49   8e-05
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1...    49   8e-05
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro...    49   8e-05
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta...    49   8e-05
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro...    49   8e-05
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro...    49   1e-04
UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family dehydroge...    49   1e-04
UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellula...    49   1e-04
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ...    48   1e-04
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re...    48   1e-04
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ...    48   1e-04
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap...    48   1e-04
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi...    48   1e-04
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s...    48   1e-04
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    48   1e-04
UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1; Rhi...    48   1e-04
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    48   1e-04
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    48   2e-04
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    48   2e-04
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan...    48   2e-04
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia...    48   2e-04
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace...    47   3e-04
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro...    47   3e-04
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja...    47   3e-04
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro...    47   3e-04
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ...    47   3e-04
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ...    47   3e-04
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe...    47   3e-04
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=...    47   4e-04
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    47   4e-04
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A...    47   4e-04
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu...    47   4e-04
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro...    47   4e-04
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba...    47   4e-04
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    46   5e-04
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro...    46   5e-04
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    46   5e-04
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re...    46   5e-04
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh...    46   5e-04
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    46   5e-04
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n...    46   5e-04
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    46   5e-04
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le...    46   7e-04
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady...    46   7e-04
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga...    46   7e-04
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst...    46   7e-04
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n...    46   0.001
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi...    46   0.001
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro...    45   0.001
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    45   0.001
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    45   0.001
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ...    45   0.001
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A...    45   0.001
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    45   0.001
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    45   0.002
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    45   0.002
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    45   0.002
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ...    45   0.002
UniRef50_Q0CK41 Cluster: Putative uncharacterized protein; n=5; ...    45   0.002
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo...    45   0.002
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    44   0.002
UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    44   0.002
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy...    44   0.002
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase...    44   0.003
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd...    44   0.003
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified...    44   0.003
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    44   0.003
UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    44   0.003
UniRef50_Q59642 Cluster: D-lactate dehydrogenase; n=5; Pediococc...    44   0.003
UniRef50_Q89388 Cluster: A53R protein; n=3; Chlorovirus|Rep: A53...    44   0.004
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro...    44   0.004
UniRef50_A2SEV8 Cluster: Phosphoglycerate dehydrogenase-related ...    44   0.004
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g...    43   0.005
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph...    43   0.005
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob...    43   0.005
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella...    43   0.005
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n...    43   0.005
UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyaci...    43   0.005
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba...    43   0.005
UniRef50_A7UH56 Cluster: Putative 2-hydroxy acid dehydrogenase; ...    43   0.005
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ...    43   0.005
UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe...    43   0.005
UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1; ...    43   0.005
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or...    43   0.007
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus...    43   0.007
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    43   0.007
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro...    43   0.007
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro...    43   0.007
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y...    43   0.007
UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7; Streptoco...    43   0.007
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr...    43   0.007
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord...    42   0.009
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a...    42   0.009
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ...    42   0.009
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro...    42   0.009
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    42   0.009
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy...    42   0.009
UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl27...    42   0.009
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ...    42   0.009
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac...    42   0.009
UniRef50_Q8G427 Cluster: Possible 2-hydroxyacid dehydrogenase; n...    42   0.011
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    42   0.011
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc...    42   0.011
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    42   0.011
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    42   0.015
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro...    42   0.015
UniRef50_A1GFX2 Cluster: D-isomer specific 2-hydroxyacid dehydro...    42   0.015
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1...    42   0.015
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog...    41   0.020
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro...    41   0.020
UniRef50_A6W9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro...    41   0.020
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a...    41   0.020
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ...    41   0.020
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha...    41   0.020
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact...    41   0.026
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|...    41   0.026
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro...    41   0.026
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col...    41   0.026
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac...    41   0.026
UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid dehydro...    41   0.026
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha...    40   0.035
UniRef50_Q7MV92 Cluster: Glycerate dehydrogenase; n=1; Porphyrom...    40   0.035
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy...    40   0.035
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro...    40   0.035
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro...    40   0.046
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba...    40   0.046
UniRef50_Q2JEY9 Cluster: Putative uncharacterized protein precur...    40   0.046
UniRef50_Q12E23 Cluster: D-isomer specific 2-hydroxyacid dehydro...    40   0.046
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase...    40   0.046
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu...    40   0.061
UniRef50_A6DPW5 Cluster: 2-hydroxyacid-family dehydrogenase; n=2...    40   0.061
UniRef50_Q9C7T6 Cluster: Phosphoglycerate dehydrogenase, putativ...    40   0.061
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ...    40   0.061
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1...    40   0.061
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh...    39   0.081
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro...    39   0.081
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ...    39   0.081
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro...    39   0.081
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    39   0.081
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro...    39   0.081
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar...    39   0.11 
UniRef50_A0PVI8 Cluster: D-3-phosphoglycerate dehydrogenase SerA...    39   0.11 
UniRef50_Q8NIV8 Cluster: Putative uncharacterized protein B13H18...    39   0.11 
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s...    39   0.11 
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ...    39   0.11 
UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase a...    38   0.14 
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    38   0.14 
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s...    38   0.14 
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter...    38   0.14 
UniRef50_Q98ST8 Cluster: Ff1c; n=6; Clupeocephala|Rep: Ff1c - Da...    38   0.19 
UniRef50_Q2EG98 Cluster: Polycystic kidney disease 1-like 3 vari...    38   0.19 
UniRef50_Q11AM6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    38   0.19 
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro...    38   0.19 
UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1; ...    38   0.19 
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555...    38   0.19 
UniRef50_Q63YS2 Cluster: D-isomer specific 2-hydroxyacid dehydro...    38   0.25 
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc...    38   0.25 
UniRef50_Q0RPA4 Cluster: Putative D-isomer specific 2-hydroxyaci...    38   0.25 
UniRef50_Q036G7 Cluster: Lactate dehydrogenase related 2-hydroxy...    38   0.25 
UniRef50_Q55F22 Cluster: Putative uncharacterized protein; n=4; ...    38   0.25 
UniRef50_Q4PEQ2 Cluster: Putative uncharacterized protein; n=1; ...    38   0.25 
UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1; ...    38   0.25 
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea...    38   0.25 
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto...    37   0.33 
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ...    37   0.33 
UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyc...    37   0.33 
UniRef50_A5VEE7 Cluster: D-isomer specific 2-hydroxyacid dehydro...    37   0.33 
UniRef50_Q6CFF2 Cluster: Yarrowia lipolytica chromosome B of str...    37   0.33 
UniRef50_O14075 Cluster: Putative 2-hydroxyacid dehydrogenase UN...    37   0.33 
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro...    37   0.43 
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro...    37   0.43 
UniRef50_Q08911 Cluster: Formate dehydrogenase 1; n=71; Eukaryot...    37   0.43 
UniRef50_Q6NXD9 Cluster: SERTA domain containing 2; n=3; Clupeoc...    36   0.57 
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute...    36   0.57 
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;...    36   0.57 
UniRef50_Q1IPG3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    36   0.57 
UniRef50_Q023X8 Cluster: Putative uncharacterized protein; n=1; ...    36   0.57 
UniRef50_A4BI79 Cluster: D-lactate dehydrogenase; n=1; Reinekea ...    36   0.57 
UniRef50_Q8VX85 Cluster: Putative NAD-dependent formate dehydrog...    36   0.57 
UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1; ...    36   0.57 
UniRef50_UPI000155367B Cluster: PREDICTED: hypothetical protein;...    36   0.75 
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    36   0.75 
UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1; Bdellov...    36   0.75 
UniRef50_Q62LP5 Cluster: Putative uncharacterized protein; n=2; ...    36   0.75 
UniRef50_Q5LSR6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    36   0.75 
UniRef50_A0R5A8 Cluster: D-isomer specific 2-hydroxyacid dehydro...    36   0.75 
UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2; ...    36   0.75 
UniRef50_A6S7X7 Cluster: Predicted protein; n=1; Botryotinia fuc...    36   0.75 
UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase; ...    36   0.75 
UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Re...    36   0.99 
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci...    36   0.99 
UniRef50_Q1V300 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    36   0.99 
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1...    36   0.99 
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro...    36   0.99 
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro...    36   0.99 
UniRef50_A0YGL0 Cluster: Dehydrogenase; n=1; marine gamma proteo...    36   0.99 
UniRef50_Q1E2M0 Cluster: Putative uncharacterized protein; n=3; ...    36   0.99 
UniRef50_A6RBH5 Cluster: Predicted protein; n=1; Ajellomyces cap...    36   0.99 
UniRef50_Q5HL54 Cluster: D-isomer specific 2-hydroxyacid dehydro...    35   1.3  
UniRef50_Q2BHH2 Cluster: Glycerate dehydrogenase; n=1; Neptuniib...    35   1.3  
UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyaci...    35   1.3  
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p...    35   1.3  
UniRef50_Q54XA2 Cluster: Putative uncharacterized protein; n=1; ...    35   1.3  
UniRef50_Q4QFA9 Cluster: ABC1 transporter-like protein; n=1; Lei...    35   1.3  
UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase; ...    35   1.3  
UniRef50_O75112 Cluster: LIM domain-binding protein 3; n=36; Eut...    35   1.3  
UniRef50_UPI0001553895 Cluster: PREDICTED: similar to C6orf205 p...    35   1.7  
UniRef50_UPI0000E26021 Cluster: PREDICTED: hypothetical protein;...    35   1.7  
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro...    35   1.7  
UniRef50_Q6FFP8 Cluster: Putative 2-hydroxyacid dehydrogenase; n...    35   1.7  
UniRef50_Q5NR73 Cluster: 2-hydroxyacid dehydrogenase; n=1; Zymom...    35   1.7  
UniRef50_Q47W88 Cluster: D-isomer specific 2-hydroxyacid dehydro...    35   1.7  
UniRef50_Q2SWA3 Cluster: Manganese/iron transporter, NRAMP famil...    35   1.7  
UniRef50_Q1LFJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro...    35   1.7  
UniRef50_Q026D8 Cluster: D-isomer specific 2-hydroxyacid dehydro...    35   1.7  
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1...    35   1.7  
UniRef50_A1VTQ3 Cluster: Putative uncharacterized protein precur...    35   1.7  
UniRef50_Q9LH95 Cluster: Arabidopsis thaliana genomic DNA, chrom...    35   1.7  
UniRef50_Q4Q5E6 Cluster: RNA guanylyltransferase, putative; n=4;...    35   1.7  
UniRef50_A7F5T0 Cluster: Putative uncharacterized protein; n=1; ...    35   1.7  
UniRef50_A1D255 Cluster: Glycerate dehydrogenase; n=1; Neosartor...    35   1.7  
UniRef50_P72357 Cluster: D-lactate dehydrogenase; n=28; Bacilli|...    35   1.7  
UniRef50_UPI000023DBF4 Cluster: predicted protein; n=1; Gibberel...    34   2.3  
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|...    34   2.3  
UniRef50_A5ZAJ9 Cluster: Putative uncharacterized protein; n=1; ...    34   2.3  
UniRef50_A4M784 Cluster: D-isomer specific 2-hydroxyacid dehydro...    34   2.3  
UniRef50_UPI0000EBC89F Cluster: PREDICTED: similar to Complement...    34   3.0  
UniRef50_UPI00006C09CB Cluster: PREDICTED: hypothetical protein;...    34   3.0  
UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome s...    34   3.0  
UniRef50_A7J7V2 Cluster: Putative uncharacterized protein N598R;...    34   3.0  
UniRef50_Q602T7 Cluster: PKD domain protein; n=1; Methylococcus ...    34   3.0  
UniRef50_Q397D5 Cluster: D-isomer specific 2-hydroxyacid dehydro...    34   3.0  
UniRef50_Q2CCV7 Cluster: Putative uncharacterized protein; n=1; ...    34   3.0  
UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibac...    34   3.0  
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc...    34   3.0  
UniRef50_A0JU75 Cluster: RDD domain containing protein; n=2; Art...    34   3.0  
UniRef50_Q5KJK5 Cluster: Glycerate-and formate-dehydrogenase, pu...    34   3.0  
UniRef50_Q2H8L6 Cluster: Putative uncharacterized protein; n=1; ...    34   3.0  
UniRef50_A1C4V8 Cluster: Glycosyl hydrolase, family 18, putative...    34   3.0  
UniRef50_Q9YCJ2 Cluster: Putative glyoxylate reductase; n=1; Aer...    34   3.0  
UniRef50_O60721 Cluster: Sodium/potassium/calcium exchanger 1 (N...    34   3.0  
UniRef50_Q8VHG2 Cluster: Angiomotin; n=21; Tetrapoda|Rep: Angiom...    34   3.0  
UniRef50_UPI0000E25C8F Cluster: PREDICTED: hypothetical protein;...    33   4.0  
UniRef50_Q8RG31 Cluster: 2-hydroxyglutarate dehydrogenase; n=4; ...    33   4.0  
UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid aminot...    33   4.0  
UniRef50_Q0S7S0 Cluster: Probable phosphoglycerate dehydrogenase...    33   4.0  
UniRef50_A1GF52 Cluster: LigA precursor; n=1; Salinispora arenic...    33   4.0  
UniRef50_Q6JX09 Cluster: GlsA-related protein; n=2; Chlamydomona...    33   4.0  
UniRef50_A5AZD0 Cluster: Putative uncharacterized protein; n=1; ...    33   4.0  
UniRef50_A5AIL2 Cluster: Putative uncharacterized protein; n=1; ...    33   4.0  
UniRef50_Q9BLF6 Cluster: D-lactate dehydrogenase; n=1; Octopus v...    33   4.0  
UniRef50_Q6IG93 Cluster: HDC06910; n=1; Drosophila melanogaster|...    33   4.0  
UniRef50_Q6MW56 Cluster: Related to DNA damage checkpoint protei...    33   4.0  
UniRef50_Q5KKJ8 Cluster: Glyoxylate reductase, putative; n=2; Fi...    33   4.0  
UniRef50_Q2H8U5 Cluster: Putative uncharacterized protein; n=4; ...    33   4.0  
UniRef50_UPI0000F2B95C Cluster: PREDICTED: hypothetical protein;...    33   5.3  
UniRef50_UPI0000F1EA78 Cluster: PREDICTED: hypothetical protein;...    33   5.3  
UniRef50_UPI0000DD80C0 Cluster: PREDICTED: hypothetical protein;...    33   5.3  
UniRef50_UPI00005A516D Cluster: PREDICTED: hypothetical protein ...    33   5.3  
UniRef50_UPI000069D9EA Cluster: Polyhomeotic-like protein 3 (hPH...    33   5.3  
UniRef50_Q9JKS4-3 Cluster: Isoform 3 of Q9JKS4 ; n=5; Eutheria|R...    33   5.3  
UniRef50_Q4KT76 Cluster: Hoar peptide; n=1; Chrysodeixis chalcit...    33   5.3  
UniRef50_Q7P6Z0 Cluster: D-lactate dehydrogenase; n=10; Bacteria...    33   5.3  
UniRef50_Q56812 Cluster: UDP-glucose dehydrogenase; n=1; Xanthom...    33   5.3  
UniRef50_Q0RE68 Cluster: Putative uncharacterized protein; n=1; ...    33   5.3  
UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;...    33   5.3  
UniRef50_Q0BWK4 Cluster: Putative uncharacterized protein; n=1; ...    33   5.3  
UniRef50_A5FZ86 Cluster: Major facilitator superfamily MFS_1; n=...    33   5.3  

>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
           3-phosphoglycerate dehydrogenase; n=1; Apis
           mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
           dehydrogenase - Apis mellifera
          Length = 478

 Score =  116 bits (280), Expect = 3e-25
 Identities = 57/97 (58%), Positives = 73/97 (75%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+++A +KGV V+N PG N++SACELTC L+  LAR+V  A  +LK GRWDR LY+G
Sbjct: 80  DNIDLEAATRKGVIVLNTPGGNSISACELTCALISNLARNVTQAVQSLKDGRWDRKLYSG 139

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
            EL+GKTLA+LG+   GR  V  RM A+GM +I FDP
Sbjct: 140 FELSGKTLAVLGMGRIGR-EVTRRMQAYGMRVIAFDP 175



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 33/62 (53%), Positives = 44/62 (70%)
 Frame = +3

Query: 51  MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 230
           M   ++SVLI D V A C ELL  +GI  TTK K+SKE+L+ E+ NH+ L+VRS T+VT 
Sbjct: 1   MSTTLRSVLISDPVDACCGELLVRHGIPVTTKYKLSKEKLIKELQNHEGLIVRSETKVTA 60

Query: 231 EV 236
           +V
Sbjct: 61  DV 62


>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA19489-PA - Nasonia vitripennis
          Length = 511

 Score =  113 bits (272), Expect = 3e-24
 Identities = 54/98 (55%), Positives = 70/98 (71%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +A + G+ V+N PG N++SACELTC ++  LAR+VV A  ++K GRWDR LY G
Sbjct: 80  DNIDIPAATRNGILVLNTPGGNSVSACELTCAVISALARNVVQAGQSMKEGRWDRKLYAG 139

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
            EL+GK L ++G    GR  VA RM AFGM II +DPF
Sbjct: 140 RELSGKALGVVGFGRIGR-EVAHRMKAFGMEIIAYDPF 176



 Score = 72.5 bits (170), Expect = 7e-12
 Identities = 33/65 (50%), Positives = 48/65 (73%)
 Frame = +3

Query: 51  MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 230
           M V+++SVL+ D V  +CA LL ++G+  TTK K+SKEEL+ E+  HD L+VRS T+VT 
Sbjct: 1   MSVNLRSVLVSDPVDERCAALLTSHGVPVTTKYKLSKEELINELQKHDGLIVRSETKVTA 60

Query: 231 EVLDA 245
           +V+ A
Sbjct: 61  DVIAA 65


>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
           Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
           sapiens (Human)
          Length = 533

 Score =  105 bits (253), Expect = 6e-22
 Identities = 50/97 (51%), Positives = 71/97 (73%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+++A +KG+ V+N P  N+LSA ELTC +++ LAR +  A+ ++K G+W+R  + G
Sbjct: 81  DNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMG 140

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
           +EL GKTL ILGL   GR  VATRM +FGM  IG+DP
Sbjct: 141 TELNGKTLGILGLGRIGR-EVATRMQSFGMKTIGYDP 176



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 25/65 (38%), Positives = 42/65 (64%)
 Frame = +3

Query: 60  DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 239
           +++ VLI D +   C ++L   G+    K  +SKEEL+ E+ + + L+VRSAT+VT +V+
Sbjct: 5   NLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVI 64

Query: 240 DAGVK 254
           +A  K
Sbjct: 65  NAAEK 69


>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
           Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
           Methanococcus jannaschii
          Length = 524

 Score =  104 bits (249), Expect = 2e-21
 Identities = 52/98 (53%), Positives = 70/98 (71%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV++A +KG+ V+NAP A+++S  ELT  LML  AR++  A+ +LK G WDR  + G
Sbjct: 75  DNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWDRKRFKG 134

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            EL GKTL ++GL GR   +V  R  AFGMNIIG+DP+
Sbjct: 135 IELYGKTLGVIGL-GRIGQQVVKRAKAFGMNIIGYDPY 171



 Score = 39.5 bits (88), Expect = 0.061
 Identities = 21/61 (34%), Positives = 35/61 (57%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
           +L+ D +     ++L   G        ++KEELL +I + D LVVRS T+VT++V++   
Sbjct: 4   ILVTDPLHEDAIKILEEVGEVEVATG-LTKEELLEKIKDADVLVVRSGTKVTRDVIEKAE 62

Query: 252 K 254
           K
Sbjct: 63  K 63


>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
           Actinobacteria (class)|Rep: D-3-phosphoglycerate
           dehydrogenase - Nocardioides sp. (strain BAA-499 /
           JS614)
          Length = 536

 Score =  102 bits (244), Expect = 8e-21
 Identities = 53/98 (54%), Positives = 67/98 (68%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DV +A + GV V+NAP +N +SA EL   LML  ARH+ PA  ALK G W RA YTG
Sbjct: 85  DNVDVRAATQAGVMVVNAPTSNIVSAAELAVALMLAAARHISPAHAALKNGEWKRARYTG 144

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           +EL  KT+ I+GL GR    VA R+ AFGM I+ +DP+
Sbjct: 145 TELYEKTVGIVGL-GRIGVLVAQRLSAFGMKIVAYDPY 181


>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
           Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
           dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
          Length = 538

 Score =  101 bits (243), Expect = 1e-20
 Identities = 49/97 (50%), Positives = 67/97 (69%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+++A ++G+ V++ PG NA+SA E TC ++L  ARH+  A   LK G W++ LY G
Sbjct: 87  DNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQAMADLKQGNWNKHLYAG 146

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
            EL GKTL+++GL   GR  VA RM AFGM  I +DP
Sbjct: 147 IELEGKTLSLIGLGRVGR-EVAMRMQAFGMRTIAYDP 182



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = +3

Query: 60  DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 239
           ++  VLI D V  +C  LL  +G   T K  +S +EL   I +++ L+VRSAT +  EVL
Sbjct: 11  NVMKVLITDSVHPQCGRLLLQHGFEVTEKPSLSPKELHAIIADYNILIVRSATSLPAEVL 70


>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 487

 Score = 99.1 bits (236), Expect = 7e-20
 Identities = 51/97 (52%), Positives = 65/97 (67%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID  +A   GV V+N PG N LSA E TC L+  LARH+  AS + K G+W+R  + G
Sbjct: 81  DNIDTVAASLHGVLVMNTPGGNTLSAAEHTCALISSLARHIPQASASTKEGKWERKQFMG 140

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
           +EL GKTLAI+GL   GR  VA RM ++G+  IG+DP
Sbjct: 141 NELFGKTLAIIGLGRIGR-EVALRMQSYGVKTIGYDP 176



 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 29/64 (45%), Positives = 44/64 (68%)
 Frame = +3

Query: 57  VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 236
           +++K VLI D V + C  +L   G+      K+SKEEL+ EIP +D L+VRSAT+V+++V
Sbjct: 4   LELKRVLISDSVDSCCKTILERNGVTVDVNTKLSKEELVSEIPKYDGLIVRSATKVSEDV 63

Query: 237 LDAG 248
           + AG
Sbjct: 64  IKAG 67


>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
           Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
           Thermotoga maritima
          Length = 306

 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 47/96 (48%), Positives = 60/96 (62%), Gaps = 1/96 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV  A +KG+ V+N PGA+A S  EL   LML  ARH+  A+ +LK G+W++    G
Sbjct: 78  DNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHIARATVSLKEGKWEKKALKG 137

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDP 571
            EL GKTL ++G       VA R  AFGM II +DP
Sbjct: 138 KELLGKTLGLIGFGNIGQEVAKRALAFGMKIIAYDP 173



 Score = 41.5 bits (93), Expect = 0.015
 Identities = 22/59 (37%), Positives = 34/59 (57%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
           V + D +  +  +LL        T   + K+EL+  IP  D LVVRSAT+VT ++++AG
Sbjct: 6   VHVNDPLDKEATQLLMNKEELEVTSEHLEKDELMKIIPEVDVLVVRSATKVTADIIEAG 64


>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
           Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
           Clostridium tetani
          Length = 533

 Score = 95.5 bits (227), Expect = 9e-19
 Identities = 48/98 (48%), Positives = 63/98 (64%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+  A K+G+ V N P +N +SACELT  L+L  +R++      LK G WDR  + G
Sbjct: 79  DNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIAKTDRFLKEGNWDRDSFMG 138

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           +EL  KTL I+GL GR    VATRM AF M +I +DP+
Sbjct: 139 TELFNKTLGIIGL-GRIGSLVATRMNAFDMKVIAYDPY 175



 Score = 39.1 bits (87), Expect = 0.081
 Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
 Frame = +3

Query: 57  VDIKSVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 233
           +D   +LIVD +  K  ELL +        K  + +E+LL  I N+D L++RS T +  E
Sbjct: 1   MDKAKILIVDKIDTKGIELLESEPNFEVDIKMGLEREKLLNIIENYDGLIIRSDTNIDIE 60

Query: 234 VLDAGVK 254
           +++   K
Sbjct: 61  LMNMAKK 67


>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
           Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
           - Dehalococcoides sp. (strain CBDB1)
          Length = 526

 Score = 95.1 bits (226), Expect = 1e-18
 Identities = 47/97 (48%), Positives = 63/97 (64%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +A   G+ V+NAP  N +SA E T  LML +ARH+  A+ +LK+G+W R  + G
Sbjct: 75  DNIDLKTATGNGIIVVNAPTGNTISATEHTLALMLAMARHIPRANASLKSGQWKRNEFVG 134

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
           SEL GKTL I+GL      +A R  A  M +IG+DPF
Sbjct: 135 SELKGKTLGIVGLGNIGSEIAKRALALEMRVIGYDPF 171



 Score = 41.1 bits (92), Expect = 0.020
 Identities = 24/64 (37%), Positives = 35/64 (54%)
 Frame = +3

Query: 63  IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
           +K VL+ D + A     L         K  +  EEL+  I  +DAL+VRS TQVT ++++
Sbjct: 1   MKKVLVSDALSATGLAPLKEIA-QVDVKTGLKPEELISIIGEYDALLVRSQTQVTADIIN 59

Query: 243 AGVK 254
           AG K
Sbjct: 60  AGKK 63


>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
           Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
           Bacillus coagulans 36D1
          Length = 541

 Score = 95.1 bits (226), Expect = 1e-18
 Identities = 47/98 (47%), Positives = 67/98 (68%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDVD+A +KG+ V+N+PG N +SA E T  +ML L+R++  A  +  AG+W+R  + G
Sbjct: 77  DNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIPQAHKSAAAGKWEREKFKG 136

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            EL  KTL I+G TG+    VA R  AFGM ++G+DP+
Sbjct: 137 VELFKKTLGIIG-TGKIGTEVAKRAKAFGMAVLGYDPY 173



 Score = 33.9 bits (74), Expect = 3.0
 Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
 Frame = +3

Query: 69  SVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           ++L+ D V  +  + L A+       +  I+ E+L   I  +D L+VR+ T+VTK++++A
Sbjct: 3   NILVTDKVSEEGLKKLYAHKDFIVEHQPGIAPEDLKATIGQYDGLIVRNQTKVTKDIIEA 62


>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
           dehydrogenase - Halothermothrix orenii H 168
          Length = 527

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 49/98 (50%), Positives = 63/98 (64%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID++ A K+G+ V N P  N +SA E T  +ML L+R++  A+ AL  G WDR  Y G
Sbjct: 75  DNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSRNIPQANQALHEGIWDRKKYMG 134

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            E+ GKTL I+GL GR   RVA R  AFGM +I  DP+
Sbjct: 135 VEVKGKTLGIIGL-GRIGSRVAVRAQAFGMKVIANDPY 171



 Score = 39.9 bits (89), Expect = 0.046
 Identities = 23/57 (40%), Positives = 31/57 (54%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
           VL+ D +  K  E+L       T    +S+EE L  I  +D L+VRS T+V KE LD
Sbjct: 4   VLVSDNISPKGIEILEQEA-DVTFNPDLSREEFLDIIGEYDGLIVRSMTEVDKEALD 59


>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
           Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
           Methanococcus vannielii SB
          Length = 523

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 48/98 (48%), Positives = 67/98 (68%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+D+A +KGV V+NAP A+++S  EL   LML  AR++  A+ +LK G WDR  + G
Sbjct: 75  DNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQATASLKKGEWDRKSFKG 134

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            E+  KTL I+GL GR   +VA R  AF MNI+ +DP+
Sbjct: 135 MEVYAKTLGIVGL-GRIGQQVAKRAQAFEMNIVAYDPY 171



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 25/58 (43%), Positives = 33/58 (56%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           +LI D +     E+L   G        IS EE+  +I + DALVVRS T VTKE++DA
Sbjct: 4   ILITDPLHESAIEILKEAGEVEIATG-ISIEEIKQKIKDADALVVRSGTTVTKEIIDA 60


>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
           cellular organisms|Rep: D-3-phosphoglycerate
           dehydrogenase - Uncultured methanogenic archaeon RC-I
          Length = 526

 Score = 93.1 bits (221), Expect = 5e-18
 Identities = 42/98 (42%), Positives = 68/98 (69%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DV +A +KG+ V NAP  N ++ACE T ++ML ++R++  A+ +LK+G+W+R+ + G
Sbjct: 76  DNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANASLKSGKWERSKFMG 135

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            E+  KTL I+GL GR    +  R  +FGM ++ +DPF
Sbjct: 136 VEVMNKTLGIIGL-GRIGGEITKRARSFGMEVLAYDPF 172



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 22/60 (36%), Positives = 42/60 (70%), Gaps = 1/60 (1%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
           VL+ D +  +  ++L +  G+    + +++KE+L+ +I +++AL++RS TQVTKEV+ AG
Sbjct: 3   VLVTDPISEEGIKILKSEPGVQVDIETRLTKEQLIEKIKDYNALIIRSETQVTKEVIAAG 62


>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
           Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
           Bacillus subtilis
          Length = 525

 Score = 93.1 bits (221), Expect = 5e-18
 Identities = 49/98 (50%), Positives = 62/98 (63%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+D A K GV VINAP  N +S  E T  ++  L RH+  A+ ++K+  W+R  Y G
Sbjct: 74  DNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSREWNRTAYVG 133

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           SEL GKTL I+GL GR    +A R  AFGM +  FDPF
Sbjct: 134 SELYGKTLGIVGL-GRIGSEIAQRRGAFGMTVHVFDPF 170


>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
           Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
           Acidobacteria bacterium (strain Ellin345)
          Length = 531

 Score = 91.5 bits (217), Expect = 1e-17
 Identities = 45/98 (45%), Positives = 66/98 (67%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNI++++A +KG+ V+N PGANA++  E T  LML LAR +  A+  + AG+W++    G
Sbjct: 77  DNIELEAATRKGIAVMNTPGANAIAVAEHTIGLMLALARFIPRATETMHAGKWEKKSLQG 136

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           +EL GKTL I+GL GR    VA R  +FGM ++  DP+
Sbjct: 137 TELRGKTLGIVGL-GRIGLEVARRAASFGMTLVAHDPY 173


>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
           Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
           Anaeromyxobacter sp. Fw109-5
          Length = 528

 Score = 91.5 bits (217), Expect = 1e-17
 Identities = 39/97 (40%), Positives = 66/97 (68%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+ +A ++GV V+N PG ++++  EL  +++L L+RHV  A+ ++KAG+W++  + G
Sbjct: 77  DNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHVAAATGSVKAGKWEKKRFQG 136

Query: 467 SELAGKTLAILGLTGRPRV-ATRMYAFGMNIIGFDPF 574
            ELAG+TL ++G+     V   R  A GM ++ FDPF
Sbjct: 137 HELAGRTLGVVGIGNIGSVLVARAVALGMRVVAFDPF 173


>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
           Symbiobacterium thermophilum|Rep: Phosphoglycerate
           dehydrogenase - Symbiobacterium thermophilum
          Length = 540

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 48/99 (48%), Positives = 65/99 (65%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYT 463
           DNIDV +A ++GV V+N PGAN  S  E    L++ +AR++  A  AL + GRWDR  + 
Sbjct: 73  DNIDVAAATERGVVVVNVPGANTYSTAEHAFGLLIAVARNIPQAHHALAREGRWDRMSFV 132

Query: 464 GSELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           G+EL GKTL I+GL GR    VA R  AFGM ++ +DP+
Sbjct: 133 GTELHGKTLGIIGL-GRIGSEVAVRARAFGMRVLAYDPY 170



 Score = 41.1 bits (92), Expect = 0.020
 Identities = 19/35 (54%), Positives = 25/35 (71%)
 Frame = +3

Query: 150 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 254
           K++ EELL  IP +DAL+ RS T+VT EVL  G +
Sbjct: 27  KVTSEELLEIIPEYDALITRSETKVTAEVLARGTR 61


>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
           Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
           Rhodopirellula baltica
          Length = 540

 Score = 90.2 bits (214), Expect = 3e-17
 Identities = 42/98 (42%), Positives = 66/98 (67%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID  +A ++G+ V+N P  N +S  E T  ++L ++R++  A+ +L  GRWDR  + G
Sbjct: 77  DNIDKPAATRRGIVVMNTPAGNTVSTAEHTFAMLLAMSRNIAAANQSLVEGRWDRKKFMG 136

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
           +++AGKTL I+G+   GR  VA+R  AF M+++ FDPF
Sbjct: 137 TQVAGKTLGIVGMGRIGR-EVASRAQAFDMDVVAFDPF 173


>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
           Planctomyces maris DSM 8797|Rep: Phosphoglycerate
           dehydrogenase - Planctomyces maris DSM 8797
          Length = 541

 Score = 90.2 bits (214), Expect = 3e-17
 Identities = 46/98 (46%), Positives = 63/98 (64%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID  +A ++G+ V+N P  N  S  E T  LM+ LAR++ PA   +K G+W+R   TG
Sbjct: 77  DNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARNIGPAYATMKEGKWERKKLTG 136

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           +++AGKTLAI+GL GR    VA R     M +IG+DPF
Sbjct: 137 TQVAGKTLAIIGL-GRIGLSVAHRAQGLEMKVIGYDPF 173


>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
           Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
           Magnetococcus sp. (strain MC-1)
          Length = 527

 Score = 89.8 bits (213), Expect = 4e-17
 Identities = 40/97 (41%), Positives = 62/97 (63%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D  +A +KG+ V+N P  NA++  EL  TL +  ARH+  A+ + KAG+W+++ + G
Sbjct: 76  DNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHIPAATASTKAGKWEKSRFMG 135

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
            ELAGKT  ++GL    R VA R+    M ++ +DPF
Sbjct: 136 RELAGKTAGVIGLGNVGRLVAQRLAGLDMKVVAYDPF 172



 Score = 38.3 bits (85), Expect = 0.14
 Identities = 19/58 (32%), Positives = 31/58 (53%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           VLI D +     E+  A G+    K  +S +ELL  I  +D + +RSAT++  + + A
Sbjct: 4   VLIADKMSPMAEEVFRARGLEVDVKVGMSPDELLACIDQYDGIAIRSATRLPAQAIAA 61


>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
           Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
           - Methanosarcina mazei (Methanosarcina frisia)
          Length = 540

 Score = 89.8 bits (213), Expect = 4e-17
 Identities = 45/98 (45%), Positives = 64/98 (65%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DVD+A KKG+ V NAP  N +SA E T  +M+ ++R++  A+ +LKA  W R  + G
Sbjct: 91  DNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSRNIPQANASLKAREWKRNKFMG 150

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            E+ GKTL ++GL GR    VA R     MN++G+DPF
Sbjct: 151 VEVKGKTLGVIGL-GRIGSEVAKRAAGLEMNLMGYDPF 187



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 21/63 (33%), Positives = 39/63 (61%)
 Frame = +3

Query: 57  VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 236
           +D+K VL+ D +  +  E+L  +         + ++EL+ +I  +DALV+RS TQVT+ +
Sbjct: 16  IDMK-VLVSDSLSNEGLEILKEH-FDIDVCTGLCEDELVEKIKGYDALVIRSGTQVTQRI 73

Query: 237 LDA 245
           ++A
Sbjct: 74  IEA 76


>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
           dehydrogenase; n=1; Candidatus Kuenenia
           stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
           dehydrogenase - Candidatus Kuenenia stuttgartiensis
          Length = 535

 Score = 89.4 bits (212), Expect = 6e-17
 Identities = 45/98 (45%), Positives = 62/98 (63%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV +A KKG+ V+N P  N +S  E T  L+  L+R V  A  ++K G+W++  +TG
Sbjct: 84  DNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSRFVPQACASVKEGKWEKKKFTG 143

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
            +L GKT  I+GL   GR +VA R  A  M +IG+DPF
Sbjct: 144 QQLTGKTFGIIGLGRVGR-QVAKRAAALEMKVIGYDPF 180



 Score = 35.5 bits (78), Expect = 0.99
 Identities = 21/61 (34%), Positives = 30/61 (49%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
           VLI D +   C E+L   G+    K  +   EL   I   D ++VRS T++T  VL+   
Sbjct: 12  VLIADDLPDVCNEILQNAGVEVLKKTGLKPPELDAVIKMCDGVIVRSNTKLTAPVLEKSE 71

Query: 252 K 254
           K
Sbjct: 72  K 72


>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
           cellular organisms|Rep: D-3-phosphoglycerate
           dehydrogenase - Archaeoglobus fulgidus
          Length = 527

 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 43/98 (43%), Positives = 62/98 (63%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+++A ++G+ V+NAPG N +S  E    LML  AR +  A  ++K G+W+R  + G
Sbjct: 75  DNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGKWERKKFMG 134

Query: 467 SELAGKTLAILGLTGRP--RVATRMYAFGMNIIGFDPF 574
            EL GKT  ++GL GR    VA R  A  MN++ +DPF
Sbjct: 135 IELRGKTAGVIGL-GRVGFEVAKRCKALEMNVLAYDPF 171



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 20/58 (34%), Positives = 36/58 (62%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           VL+ + +  +  + +   G+    K  +S+EEL+ E+P ++A+VVRS T+V  EV+ A
Sbjct: 3   VLVAEPISEEAIDYMRKNGLEVEVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQA 60


>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep:
           D-3-phosphoglycerate dehydrogenase - Syntrophobacter
           fumaroxidans (strain DSM 10017 / MPOB)
          Length = 525

 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 44/98 (44%), Positives = 65/98 (66%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV +A  +G  V+N PGANA +A E T  +ML LARH+  A+ +++ GRWD+  + G
Sbjct: 76  DNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQATQSMREGRWDKKRFMG 135

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           +EL  +TL I+GL G+    VA R  +  M+++G DP+
Sbjct: 136 TELFHQTLGIIGL-GKIGSIVADRALSMKMDVLGHDPY 172



 Score = 36.7 bits (81), Expect = 0.43
 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
           VLI DG+      +L A  GI      +   EE+   +P++DA++VRS T++T E+++
Sbjct: 3   VLICDGMHEVGLSILRAAEGIDVDVPDQPGAEEIKAMLPDYDAVIVRSRTRITAELIE 60


>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
           D-3-phosphoglycerate dehydrogenase; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
           purpuratus
          Length = 493

 Score = 87.4 bits (207), Expect = 2e-16
 Identities = 49/106 (46%), Positives = 61/106 (57%), Gaps = 2/106 (1%)
 Frame = +2

Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 472
           IDV    +   G    PG N LSA E TC ++  L+R +  A   LKAG+WDR  + GSE
Sbjct: 46  IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAHATLKAGKWDRKAFMGSE 105

Query: 473 LAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPFRVC*SVRQFH 604
           L GKTL I+GL   GR  VA RM +FGM  IGFDP       +Q++
Sbjct: 106 LYGKTLGIVGLGRIGR-EVAQRMQSFGMTTIGFDPIVPAEEAKQYN 150



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 23/45 (51%), Positives = 27/45 (60%)
 Frame = +3

Query: 51  MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIP 185
           M   +K VLI D V  +CAE+L   GI      K+SKEELL EIP
Sbjct: 1   MAFSLKKVLISDSVSPRCAEILRENGIEVDNNTKLSKEELLAEIP 45


>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
           phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
           Predicted dehydrogenase related to phosphoglycerate
           dehydrogenase - Methanopyrus kandleri
          Length = 522

 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 44/98 (44%), Positives = 65/98 (66%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV +A ++G+ V+NAP ++++S  E T  L+L LAR +  A  +++ G WDR  + G
Sbjct: 75  DNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQADRSVRRGEWDRKRFMG 134

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            ELAGKTL ++GL GR   +VA R  AF M +  +DP+
Sbjct: 135 VELAGKTLGLIGL-GRIGQQVAKRAKAFEMEVTAYDPY 171


>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep:
           D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
           erythraea (strain NRRL 23338)
          Length = 316

 Score = 86.2 bits (204), Expect = 5e-16
 Identities = 45/97 (46%), Positives = 64/97 (65%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+D+A  +G+ V+ APG+N+ +  ELT  LM+  AR +  A TA+ AG W + LY G
Sbjct: 82  DNIDLDAARARGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTAVVAGDWPK-LY-G 139

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
            ELAG+TL ++G     R +A    AFGM ++G+DPF
Sbjct: 140 PELAGRTLGVIGFGRIGRLLAGYAQAFGMTVVGYDPF 176


>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
           Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
           - Agrobacterium tumefaciens (strain C58 / ATCC 33970)
          Length = 354

 Score = 85.4 bits (202), Expect = 9e-16
 Identities = 39/97 (40%), Positives = 60/97 (61%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDVD+A ++ + V+ A GANALS  E   TL+  + + +VP  + ++AGRW++A Y+G
Sbjct: 105 DNIDVDAASRREIPVVVAAGANALSVAEHAITLLFAVVKRIVPLDSGIRAGRWEKAGYSG 164

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
            ELAG  + ++G     R  A     FG+ +  +DPF
Sbjct: 165 KELAGMIIGLVGFGAIARQTAVFARGFGLKVQAYDPF 201


>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
           dehydrogenase - Opitutaceae bacterium TAV2
          Length = 529

 Score = 85.4 bits (202), Expect = 9e-16
 Identities = 41/98 (41%), Positives = 65/98 (66%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DV++A ++GV V+N P  N ++  ELT T +L  +R V  A+ +++ G+WDR  ++G
Sbjct: 76  DNVDVEAATERGVVVMNTPAGNTIATAELTFTHILCGSRPVSQAAASMREGKWDRKSFSG 135

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            EL  KTL ++G+ GR    VA R  AFGM ++ +DP+
Sbjct: 136 VELFKKTLGVIGM-GRIGGEVARRAVAFGMKVLAYDPY 172


>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
           Chloroflexi (class)|Rep: D-3-phosphoglycerate
           dehydrogenase - Roseiflexus sp. RS-1
          Length = 524

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 40/97 (41%), Positives = 66/97 (68%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+++A ++G+ V+NAP +N+++  ELT  L+L LARH+  A +++ AG+W+R  + G
Sbjct: 75  DNIDLEAATRQGIMVVNAPASNSVAVAELTIALILSLARHIPQAHSSVVAGKWERNRFMG 134

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDP 571
            E+  KTL ++GL GR    VA R     M+++ +DP
Sbjct: 135 FEVRNKTLGLVGL-GRIGAEVARRARGLEMHVVAYDP 170



 Score = 40.3 bits (90), Expect = 0.035
 Identities = 19/39 (48%), Positives = 27/39 (69%)
 Frame = +3

Query: 144 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK*R 260
           +  + K  L+  +P +DAL+VRSAT+VT EVL AG + R
Sbjct: 27  RTDLDKAGLIAILPEYDALIVRSATRVTAEVLAAGTRLR 65


>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
           Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
           - Mycobacterium leprae
          Length = 528

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 42/98 (42%), Positives = 65/98 (66%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DVD+A  +GV V+NAP +N  SA E    L+L  +R +  A  +L+A  W R+ ++G
Sbjct: 77  DNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHIWKRSSFSG 136

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           +E+ GKT+ ++GL GR    VA R+ AFG ++I +DP+
Sbjct: 137 TEIFGKTVGVVGL-GRIGQLVAARIAAFGAHVIAYDPY 173



 Score = 33.1 bits (72), Expect = 5.3
 Identities = 17/32 (53%), Positives = 21/32 (65%)
 Frame = +3

Query: 159 KEELLMEIPNHDALVVRSATQVTKEVLDAGVK 254
           + +LL  +P  DAL+VRSAT V  EVL A  K
Sbjct: 34  RTKLLAAVPEADALLVRSATTVDAEVLAAAPK 65


>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
           Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
           - Aquifex aeolicus
          Length = 533

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 40/97 (41%), Positives = 60/97 (61%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D++ A K+G+ V+N PGAN + A ELT   ML + R+   A  ++   +WDR  + G
Sbjct: 77  DNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAHESMLNYKWDRKKFMG 136

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
            EL G+ L I+GL     +VA R  AFGM ++ +DP+
Sbjct: 137 EELYGRILGIIGLGNIGSQVAIRAKAFGMKVMAYDPY 173



 Score = 39.1 bits (87), Expect = 0.081
 Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
           VLI D +  +  ELL     +    +  IS EELL  I + DA++ RS T VTKE+L+  
Sbjct: 4   VLITDPIAPEGIELLQKDPEVEVYNEPDISYEELLEIIKDFDAIITRSRTPVTKELLERA 63

Query: 249 VK 254
            K
Sbjct: 64  EK 65


>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
           Planctomyces maris DSM 8797|Rep: Phosphoglycerate
           dehydrogenase - Planctomyces maris DSM 8797
          Length = 316

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 46/98 (46%), Positives = 59/98 (60%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D + A +KG+ V   P AN+LS  ELT  LML L R +  A      G W+R  +TG
Sbjct: 77  DNVDTEYAHEKGIVVCFTPDANSLSVAELTIGLMLALMRKIPEARQDTLTGGWNRLKFTG 136

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           +EL GK+  ++GL GR     ATR  AFGMNI+  DPF
Sbjct: 137 TELYGKSFGLIGL-GRIGSFTATRAKAFGMNILAADPF 173


>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep:
           D-3-phosphoglycerate dehydrogenase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 527

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 39/97 (40%), Positives = 61/97 (62%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+++A K+G+ V NAP +N ++A E T  LML +AR +  A  +L+ G W+RA + G
Sbjct: 74  DNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRIPAADASLRRGEWNRAAFKG 133

Query: 467 SELAGKTLAILGLTGRPRVATR-MYAFGMNIIGFDPF 574
            E+A KTL ++GL     +  R     GM ++ +DP+
Sbjct: 134 VEVAEKTLGLVGLGHVGSIVARGALGMGMRVLAYDPY 170



 Score = 36.7 bits (81), Expect = 0.43
 Identities = 22/58 (37%), Positives = 32/58 (55%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           VL+ + +  +  ELL            +S  ELL  I  +D L+VRSAT+VT EV++A
Sbjct: 3   VLVTEKLAERGVELLRRE-FEVDVLLGLSPGELLERIGEYDGLIVRSATKVTAEVIEA 59


>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
           chloroplast precursor; n=13; Magnoliophyta|Rep:
           D-3-phosphoglycerate dehydrogenase, chloroplast
           precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 624

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 41/98 (41%), Positives = 61/98 (62%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+ +A + G  V+NAP AN ++A E    L+  +AR+V  A  ++KAG+W+R+ Y G
Sbjct: 157 DNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGKWERSKYVG 216

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
             L GKTLA++G  G+    VA R    GM +I  DP+
Sbjct: 217 VSLVGKTLAVMGF-GKVGTEVARRAKGLGMTVISHDPY 253



 Score = 39.5 bits (88), Expect = 0.061
 Identities = 24/67 (35%), Positives = 38/67 (56%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
           +L+ + +G     LL  +G    +   +S E+L  ++   DAL+VRS T+VT+EV +A  
Sbjct: 85  ILVTEKLGEAGVNLLREFGDVDCSY-DLSPEDLKKKVAESDALIVRSGTKVTREVFEA-A 142

Query: 252 K*RWSVV 272
           K R  VV
Sbjct: 143 KGRLKVV 149


>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
           dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
           dehydrogenase and related dehydrogenases -
           Thermoanaerobacter tengcongensis
          Length = 533

 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 44/98 (44%), Positives = 64/98 (65%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV++A ++G+ V+N P  N ++A ELT  LML +AR++  A  A   G + R  + G
Sbjct: 74  DNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIARNIPQAYHAALNGDFRRDRFKG 133

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            EL GKT+ I+GL GR    VA+R+ AF M +I +DP+
Sbjct: 134 VELNGKTVGIIGL-GRIGSLVASRLAAFNMRVIAYDPY 170



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 21/61 (34%), Positives = 37/61 (60%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
           +++ + +     + L  Y      K  IS+EELL  I ++DA++VRSAT+V +E+++ G 
Sbjct: 3   IIVTEKISENGIDYLKKYA-DVDVKTNISREELLEVIKDYDAIIVRSATKVDRELIEKGE 61

Query: 252 K 254
           K
Sbjct: 62  K 62


>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
           Fungi/Metazoa group|Rep: D-3-phosphoglycerate
           dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
           DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
           ATCC 1020 / DSM 3700 / NRRL 181))
          Length = 582

 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 40/98 (40%), Positives = 64/98 (65%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DV+ A K G+ V+N+P  N  +A E T  L++ +AR++  A ++LK+G+W+R+ + G
Sbjct: 82  DNVDVEEATKLGIVVVNSPSGNIGAAAEHTIALLIAMARNIPEACSSLKSGKWERSKFVG 141

Query: 467 SELAGKTLAILGLTGRP--RVATRMYAFGMNIIGFDPF 574
            E+ GKTL+I+GL G+    VA      GMN+   DP+
Sbjct: 142 VEVKGKTLSIIGL-GKVGLTVARLAKGLGMNVNALDPY 178



 Score = 33.9 bits (74), Expect = 3.0
 Identities = 21/58 (36%), Positives = 32/58 (55%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           VL+ + +      LL A  +    +  +  +ELL  IP ++ALVVRS T+VT  +L A
Sbjct: 11  VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTGNLLRA 67


>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
           Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
           Oceanobacillus iheyensis
          Length = 528

 Score = 82.6 bits (195), Expect = 7e-15
 Identities = 45/98 (45%), Positives = 61/98 (62%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+++A + GV V+NAP  N  SA E T  +++ L+R++  A  ALK  +WDR  + G
Sbjct: 78  DNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQAYHALKQKQWDRKRFVG 137

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            EL  KTL I+GL GR    VA R     MN+I +DPF
Sbjct: 138 VELKQKTLGIVGL-GRIGAEVAARAKGQRMNVIAYDPF 174


>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
           Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
           Staphylococcus haemolyticus (strain JCSC1435)
          Length = 532

 Score = 82.6 bits (195), Expect = 7e-15
 Identities = 41/98 (41%), Positives = 63/98 (64%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+D+A  +G+ VINAP  N +SA E +  ++L +AR++  A  +LK   W+R  + G
Sbjct: 78  DNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARNIPQAHASLKNKEWNRKAFKG 137

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            EL  KTL ++G  GR    VA R+ +FGM ++ +DP+
Sbjct: 138 VELYQKTLGVIG-AGRIGIGVAQRLQSFGMKVLAYDPY 174



 Score = 33.9 bits (74), Expect = 3.0
 Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = +3

Query: 69  SVLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
           ++L+ D +     + LLN        K  + ++ LL  I +++ L+VRS TQVT++V++
Sbjct: 4   NILVSDPISTDGLQSLLNHSDFNVDIKTDLDEQSLLDIIGDYEGLIVRSQTQVTQQVIE 62


>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic region:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding; n=2;
           Bacteria|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic region:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding - delta
           proteobacterium MLMS-1
          Length = 304

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 59/96 (61%), Gaps = 1/96 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DV +A KKGV V+NAP  NA +A E   ++M+ L R++  A+ ++KAG+W++  + G
Sbjct: 75  DNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMALTRNIPQATASMKAGKWEKKKFQG 134

Query: 467 SELAGKTLAILGLTGRPRV-ATRMYAFGMNIIGFDP 571
            E+  K   ++G+    R+ A R     M +I FDP
Sbjct: 135 HEVTAKVAGVVGIGRIGRIFAERAMGLRMKVIAFDP 170



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 22/58 (37%), Positives = 36/58 (62%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           VLI D +     +++   G+    +  +S EEL+  IP +D LV+RSA++VT E+L+A
Sbjct: 3   VLISDNLAPVGEKIMRDAGLEVDVRTGLSPEELVKIIPAYDGLVIRSASKVTAEILEA 60


>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
           Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
           Synechocystis sp. (strain PCC 6803)
          Length = 554

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 38/98 (38%), Positives = 63/98 (64%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV +A ++G+ V+N+P  N ++A E    +M+ LARH+  A+ ++K  +W+R  + G
Sbjct: 103 DNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESKWERKQFIG 162

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           +E+  KTL ++GL G+    VA    A GM ++ +DPF
Sbjct: 163 TEVYKKTLGVVGL-GKIGSHVAGVAKAMGMKLLAYDPF 199



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 18/59 (30%), Positives = 36/59 (61%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
           VL+ D +     ++L         K  +S+ E++  +P +DA+++RSAT+VT++++ AG
Sbjct: 32  VLVSDSIDQVGIDILKQVA-QVDVKTGLSEAEIIDIVPEYDAIMLRSATKVTEKIIQAG 89


>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
           Bacteria|Rep: Phosphoglycerate dehydrogenase -
           Leptospirillum sp. Group II UBA
          Length = 535

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 38/98 (38%), Positives = 64/98 (65%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+++A ++G+ V+N PG N ++  E T +L++ +AR +  A+ + KAG+W+++ + G
Sbjct: 79  DNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRIPQANASNKAGKWEKSKFMG 138

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            EL  KTL I+G+ G+    VA       MNII FDP+
Sbjct: 139 VELFQKTLGIVGM-GKIGQHVAQIARGIAMNIIAFDPY 175



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 24/63 (38%), Positives = 35/63 (55%)
 Frame = +3

Query: 51  MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 230
           M  DI+ +LI D +      +    G     K K+S +EL  EI  +D LV+RS T+VT+
Sbjct: 1   MSSDIR-ILISDAISEDGVRIFQKAGFHVDMKTKLSPQELAQEISQYDGLVIRSGTKVTR 59

Query: 231 EVL 239
           E+L
Sbjct: 60  EIL 62


>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
           n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
           Rattus norvegicus
          Length = 316

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 43/97 (44%), Positives = 61/97 (62%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+++++A  K + V+N P   +LSA ELTC +++ L R + P       G+WD+  + G
Sbjct: 75  DNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVCLTRQIPP-------GKWDQEEFMG 127

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
           +EL GKTL ILGL   GR  V T+M AF M  +GFDP
Sbjct: 128 TELNGKTLGILGLGRIGR-EVTTQMQAFRMKAVGFDP 163



 Score = 33.5 bits (73), Expect = 4.0
 Identities = 20/60 (33%), Positives = 31/60 (51%)
 Frame = +3

Query: 60  DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 239
           ++  VLI D +   C +LL   G+    K  +SKEEL++EI + +   V +    T E L
Sbjct: 5   NLHKVLISDILDPGCWKLLKDGGLQVVEKQNLSKEELIVEIQDCETTKVTADVTNTAEKL 64


>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
           Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
           dehydrogenase - Bdellovibrio bacteriovorus
          Length = 328

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 43/99 (43%), Positives = 62/99 (62%), Gaps = 2/99 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+ID+++  K GV V++ P AN  SA +LT  L+L    ++  A   +KAG W+R   TG
Sbjct: 77  DHIDLEATQKWGVTVMHTPTANIESAAQLTWGLVLSCVNNIQAAHKMVKAGEWNRDQITG 136

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPFR 577
            ELAG+   I+GL GR   RVA    AFGMN++ +DP++
Sbjct: 137 IELAGRNYGIVGL-GRIGSRVAELAQAFGMNVVAYDPYQ 174


>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
           Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
           Haloquadratum walsbyi
          Length = 536

 Score = 79.4 bits (187), Expect = 6e-14
 Identities = 40/98 (40%), Positives = 60/98 (61%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+D+A + GV V NAP  N  +A E T  +    AR +  A   L+ G W ++ Y G
Sbjct: 79  DNIDIDAATEHGVIVANAPEGNVRAAAEHTVAMTFAGARSIPQAHARLRTGEWAKSEYLG 138

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           +E+ GKTL ++GL GR    VA R+ + GM+++ +DP+
Sbjct: 139 TEVNGKTLGVVGL-GRVGQEVAKRLESLGMDLVAYDPY 175



 Score = 36.7 bits (81), Expect = 0.43
 Identities = 23/58 (39%), Positives = 30/58 (51%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           VL+ D +     E L A G +  T   I  E LL  I + +ALVVRS T V + V +A
Sbjct: 7   VLVTDPIDDAGLERLRAAGHSVETAYDIGDEALLNTITDVNALVVRSGTDVNEAVFEA 64


>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
           Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
           Brucella melitensis
          Length = 538

 Score = 79.0 bits (186), Expect = 8e-14
 Identities = 35/97 (36%), Positives = 59/97 (60%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+ +A ++G+ V+N P  N+++  E    LM  +AR +  A T+ +AG+W++  + G
Sbjct: 84  DNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLPEADTSTRAGKWEKNRFMG 143

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
            E+ GKTL ++G       VATR     M+++ FDPF
Sbjct: 144 VEITGKTLGVVGCGNIGSIVATRGIGLKMHVVAFDPF 180


>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Delftia acidovorans SPH-1
          Length = 354

 Score = 79.0 bits (186), Expect = 8e-14
 Identities = 44/96 (45%), Positives = 57/96 (59%), Gaps = 2/96 (2%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 469
           NIDV +A ++G+ V   PGANA S  E+T  LM   AR +      L+AGRW RA   G 
Sbjct: 107 NIDVAAASQRGIPVYVTPGANAQSVAEMTLGLMFAAARRIAWMDAELRAGRWSRA-QDGL 165

Query: 470 ELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
           EL+G+TL +LG    G+ RVA    A GM ++ FDP
Sbjct: 166 ELSGRTLGLLGFGQVGQ-RVARVALALGMQVVAFDP 200


>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr3 scaffold_8, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 653

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 39/98 (39%), Positives = 59/98 (60%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+ +A + G  V+NAP AN ++A E    L+  +AR+V  A  ++K+G+W R  Y G
Sbjct: 186 DNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQADASVKSGKWQRNKYVG 245

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
             L GKTLA++G  G+    V  R    GM++I  DP+
Sbjct: 246 VSLVGKTLAVMGF-GKVGSEVTRRAKGLGMHVIAHDPY 282



 Score = 37.9 bits (84), Expect = 0.19
 Identities = 22/59 (37%), Positives = 35/59 (59%)
 Frame = +3

Query: 69  SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           +VL+ + +GA   +LL  +         +S EEL  +I   DAL+VRS T+V++EV +A
Sbjct: 113 TVLVAEKLGAAGLDLLKDFANVDCAY-NLSPEELCTKISLCDALIVRSGTKVSREVFEA 170


>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
           Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
           - Pyrobaculum aerophilum
          Length = 307

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 40/95 (42%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DV+ A KKG+ V++AP A + S  ELT  L+  +AR +   +  +KAG W +  Y G
Sbjct: 75  DNVDVEYAVKKGIAVVSAPNAPSQSVAELTIGLLFSVARRIPLLNAKVKAGEWPKGKYIG 134

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFD 568
            E+AGKT+ I+G     R VA    + GMNI+  D
Sbjct: 135 IEIAGKTMGIVGFGRIGRFVAQMAKSLGMNILASD 169



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 22/60 (36%), Positives = 33/60 (55%)
 Frame = +3

Query: 69  SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
           S LIVD V     E L   GI       ISK++L+  I N++ L+ R   ++ K+++DAG
Sbjct: 2   SALIVDKVDETLKERLERIGIKVDLAPGISKDDLIKIIKNYNILIFRGRLKIDKDIMDAG 61


>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 319

 Score = 77.4 bits (182), Expect = 2e-13
 Identities = 45/108 (41%), Positives = 58/108 (53%), Gaps = 3/108 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           DNIDV +A K G+ V N P AN  +  EL  T ML   RH++P   A++AG +D R    
Sbjct: 76  DNIDVKAATKYGIKVTNTPSANINAVAELVLTFMLASTRHLLPIDEAVRAGNFDIRNQLF 135

Query: 464 GSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPFRVC*SVRQF 601
           G EL GKT+ I+G    GR          GMNI+ FDP+    SV  +
Sbjct: 136 GYELNGKTVGIIGFGNIGRLIAEKCRLGLGMNIVVFDPYVTAESVEPY 183


>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Victivallis vadensis
           ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Victivallis vadensis ATCC
           BAA-548
          Length = 524

 Score = 77.4 bits (182), Expect = 2e-13
 Identities = 35/96 (36%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + ID+  A K  + V+N PGAN+ +  E    +ML  +RH++PA  + + G W+++ + G
Sbjct: 75  NTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLIPADISTRKGDWEKSKFMG 134

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDP 571
            EL GKT+ ILGL    + +  R+  F M ++G+DP
Sbjct: 135 RELTGKTVGILGLGHIGQLLVKRLAGFEMKVLGYDP 170


>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
           ethanolicus|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Thermoanaerobacter
           ethanolicus X514
          Length = 320

 Score = 77.0 bits (181), Expect = 3e-13
 Identities = 41/97 (42%), Positives = 61/97 (62%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+++A KKG+ V N P AN  S  +L   LMLVLAR+++     +K+G W R +  G
Sbjct: 84  DNVDLNAAKKKGIVVTNTPNANNNSVADLVIGLMLVLARNLLAVDRIVKSGGWKRIM--G 141

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
           +E+ GKTL I+GL    + VA R   F MN++ +D +
Sbjct: 142 TEIYGKTLGIIGLGKIGKGVAKRAKGFDMNVLCYDVY 178


>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
           tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
           tumefaciens (strain C58 / ATCC 33970)
          Length = 317

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 38/97 (39%), Positives = 56/97 (57%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+D+A + G+ V NAPG NA +  ELT  L+L   R +     AL+ G WDR  + G
Sbjct: 83  DNIDIDAAHRHGIAVTNAPGGNANAVAELTLGLILSAMRRIPYLHDALRGGAWDR--FVG 140

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
            EL G+ + +LG     R +A ++  F + +I +D F
Sbjct: 141 QELIGRRVGLLGFGNIARKIARKLCGFDVEVIAYDKF 177


>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
           FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Arthrobacter sp. (strain FB24)
          Length = 319

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 2/100 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+IDV++A + G+ V+ APGAN+    ELT  L+L  +R +      LK+G+W+R    G
Sbjct: 95  DSIDVEAAERLGINVLTAPGANSQGVAELTIALILAGSRSIPWHDAQLKSGQWNRR--PG 152

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPFRV 580
           +E++GK L ++G    GR RVAT     GM +I FD + V
Sbjct: 153 NEVSGKVLGLIGCGQIGR-RVATMALGLGMKVIAFDEYPV 191


>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Thermosinus
           carboxydivorans Nor1|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
           carboxydivorans Nor1
          Length = 317

 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 42/95 (44%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + IDV +A   G+ V   PGAN +S  EL   LML +ARH+      ++ G W R   TG
Sbjct: 82  NTIDVAAAAAYGIPVTITPGANNISVAELAIGLMLAVARHIPQMDGIVRRGGWSR--MTG 139

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFD 568
           SEL GK L I+G+      VA R +AFGM II +D
Sbjct: 140 SELYGKVLGIIGMGSIGCEVAKRAHAFGMKIIAYD 174


>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Burkholderia multivorans ATCC 17616
          Length = 452

 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 41/98 (41%), Positives = 56/98 (57%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D ID D+A  +G+ V  A GANA +  E    L+L  A+ V      ++ G WD+A +  
Sbjct: 220 DVIDQDAAAARGIAVRAAVGANAAAVAEHAWALILACAKSVPQLDMRMREGHWDKATHKS 279

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
            EL G+TL ++GL   GR RVA    AFGM ++ FDPF
Sbjct: 280 VELDGRTLGLVGLGAIGR-RVAAIGVAFGMKVLAFDPF 316


>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
           Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
           Deinococcus radiodurans
          Length = 544

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 40/98 (40%), Positives = 59/98 (60%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID++ A ++G+ V+NAP +N +SA EL    ++  AR +  +    +AG WDR  + G
Sbjct: 92  DNIDLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGEWDRK-FLG 150

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            EL  KTL I+GL GR    VA R     MN++ +DP+
Sbjct: 151 LELTDKTLGIVGL-GRIGSIVADRAQGLHMNVVAYDPY 187



 Score = 39.1 bits (87), Expect = 0.081
 Identities = 17/44 (38%), Positives = 28/44 (63%)
 Frame = +3

Query: 114 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           L+  G     +  + +EE L  +P++DAL+ RS T+V +E+LDA
Sbjct: 33  LDHEGFQIDYQGNLEREETLRRLPDYDALITRSRTKVDRELLDA 76


>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
           KIN4/I|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Ignicoccus hospitalis
           KIN4/I
          Length = 308

 Score = 72.9 bits (171), Expect = 5e-12
 Identities = 41/96 (42%), Positives = 59/96 (61%), Gaps = 2/96 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+++A +KG+ V+NAP A   +  EL   +M+VLAR    +   L  G W++ +  G
Sbjct: 77  DNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLARRAHYSYRKLLEGEWEKVM--G 134

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFD 568
            ELAGKTL ++G    GR  VA +  A GMN+I +D
Sbjct: 135 FELAGKTLGVVGFGRIGR-EVAKKAKALGMNVIAYD 169


>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
           Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
           Clostridium acetobutylicum
          Length = 305

 Score = 72.5 bits (170), Expect = 7e-12
 Identities = 37/92 (40%), Positives = 54/92 (58%), Gaps = 1/92 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV  A  KG+ V N P A++ S  EL    M  ++R +  A+  ++ G+W++  YTG
Sbjct: 79  DNIDVTYARDKGLTVNNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWEKKAYTG 138

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNII 559
           +E+ GKTL ++G     R VA R  A GM +I
Sbjct: 139 TEIFGKTLGLIGFGRIAREVAKRAEALGMKVI 170



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 20/29 (68%), Positives = 25/29 (86%)
 Frame = +3

Query: 159 KEELLMEIPNHDALVVRSATQVTKEVLDA 245
           K+ELL++I   D LVVRSAT+VTKEV+DA
Sbjct: 32  KDELLVKIKEFDVLVVRSATKVTKEVIDA 60


>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
           WSM419|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
          Length = 328

 Score = 72.5 bits (170), Expect = 7e-12
 Identities = 41/97 (42%), Positives = 59/97 (60%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +N+D++SA ++GV V+ A GAN  S  EL   L L +AR +     +++A +W+R+ Y G
Sbjct: 79  NNVDIESATRRGVPVLIADGANGKSVAELAVGLALSVARKITTQDASIRARQWNRSAY-G 137

Query: 467 SELAGKTLAIL--GLTGRPRVATRMYAFGMNIIGFDP 571
            + AGKT  I+  G  GR RVA  + A  M II FDP
Sbjct: 138 LQFAGKTAGIVAFGAIGR-RVAEILRAMDMRIIAFDP 173


>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
           Deltaproteobacteria|Rep: D-3-phosphoglycerate
           dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
          Length = 532

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 35/97 (36%), Positives = 57/97 (58%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+ +A K GV V+N P  N ++  E T  +M+ L R++   + +L++G+W++    G
Sbjct: 79  DNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQGTLSLRSGQWEKKKLQG 138

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDP 571
            E+  KTL ++G  G+    VA R     MN+I FDP
Sbjct: 139 REVFNKTLGVIGF-GKIGSIVADRARQLKMNVIVFDP 174



 Score = 46.0 bits (104), Expect = 7e-04
 Identities = 25/60 (41%), Positives = 36/60 (60%), Gaps = 1/60 (1%)
 Frame = +3

Query: 72  VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
           VL+ D + A   + L N  G A   K  +  EEL   I  +DAL++RSAT+VT ++L+AG
Sbjct: 5   VLVSDTIDASGVSRLENESGFAVDVKTGLPPEELKSIIGQYDALIIRSATKVTADILEAG 64


>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
           Clostridium perfringens|Rep: D-3-phosphoglycerate
           dehydrogenase - Clostridium perfringens
          Length = 301

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 41/96 (42%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV  A + G+ V N P A++ S  E+    M  LAR +  ++  +KAG W +  Y G
Sbjct: 78  DNIDVQYAEQNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQSNITMKAGLWKKKDYVG 137

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFD 568
            EL GKTL I+G+ GR    +A +  A GM II FD
Sbjct: 138 VELEGKTLGIIGM-GRIGSELAKKCTALGMKIIYFD 172



 Score = 35.5 bits (78), Expect = 0.99
 Identities = 19/61 (31%), Positives = 32/61 (52%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
           +L+ DG+  K    L   G    T      E+L  +I   D +V+RSAT++ +E++D  +
Sbjct: 4   ILLNDGLDKKAISNLEFLGFDVDTN-HYDIEDLKEKIKKVDCIVIRSATKIRRELIDEAI 62

Query: 252 K 254
           K
Sbjct: 63  K 63


>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
           SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Petrotoga mobilis SJ95
          Length = 310

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 37/100 (37%), Positives = 57/100 (57%), Gaps = 2/100 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDVD+A  KG+ V+N PG N+LS  EL   ++L + RH+   +  LK  +W++    G
Sbjct: 76  DNIDVDTAKLKGITVLNTPGQNSLSVAELVIGMVLDIYRHITRGTIGLKNEQWEKKQLEG 135

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPFRV 580
            EL+ KT  I+G    G+  +A  +  F  N + +D F +
Sbjct: 136 FELSQKTFGIIGFGYVGK-NLAQLLKGFQTNTLVYDVFEI 174



 Score = 33.9 bits (74), Expect = 3.0
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +3

Query: 141 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
           T   + K+ L  +I   D L+VRSAT+VTKE+L+
Sbjct: 27  TSEHLEKDVLKDKIKEIDVLIVRSATKVTKEILE 60


>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
           Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
           subsp. japonica (Rice)
          Length = 666

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 43/110 (39%), Positives = 60/110 (54%), Gaps = 14/110 (12%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---------- 436
           DN+D+ +A + G  V+NAP AN ++A E    L+  +AR+V  A  ALKA          
Sbjct: 152 DNVDLQAATEAGCLVVNAPTANTVAAAEHGIALLASMARNVSQADAALKAVYSRTLTVFT 211

Query: 437 --GRWDRALYTGSELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
             G+W R  Y G  L GKTLA++G  G+    VA R    GM++I  DP+
Sbjct: 212 AQGKWQRTKYVGVSLVGKTLAVMGF-GKVGSEVARRAKGLGMHVIAHDPY 260



 Score = 39.9 bits (89), Expect = 0.046
 Identities = 18/32 (56%), Positives = 25/32 (78%)
 Frame = +3

Query: 153 ISKEELLMEIPNHDALVVRSATQVTKEVLDAG 248
           +S  ELL ++   DAL+VRS T+VT+EVL+AG
Sbjct: 106 MSPAELLAKVAQFDALIVRSGTKVTREVLEAG 137


>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Aspergillus fumigatus|Rep: D-3-phosphoglycerate
           dehydrogenase - Aspergillus fumigatus (Sartorya
           fumigata)
          Length = 635

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 30/70 (42%), Positives = 50/70 (71%)
 Frame = +2

Query: 296 DVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSEL 475
           DV+ A K G+ V+N+P  N  +A E T  L++ +AR++  A ++LK+G+W+R+ + G E+
Sbjct: 109 DVEEATKLGIVVVNSPSGNIGAAAEHTIALLMAMARNIPEACSSLKSGKWERSKFVGVEV 168

Query: 476 AGKTLAILGL 505
            GKTL+I+GL
Sbjct: 169 KGKTLSIIGL 178



 Score = 34.3 bits (75), Expect = 2.3
 Identities = 21/58 (36%), Positives = 32/58 (55%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           VL+ + +      LL A  +    +  +  +ELL  IP ++ALVVRS T+VT  +L A
Sbjct: 11  VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTANLLRA 67


>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=2; Desulfitobacterium
           hafniense|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Desulfitobacterium
           hafniense (strain DCB-2)
          Length = 320

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 39/95 (41%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+ID+ +A  +G+ V NAPG NA S  +L    ML LAR +V A    + G W   +  G
Sbjct: 84  DSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSLARQIVSADKRTRDGFWGTVM--G 141

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFD 568
            ++ GKTL +LGL    + V  R   F MNI+G+D
Sbjct: 142 KDVYGKTLGVLGLGQIGKGVIRRASGFDMNILGYD 176


>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase family protein; n=1; Arthrobacter
           aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase family protein - Arthrobacter aurescens
           (strain TC1)
          Length = 329

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 37/98 (37%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 460
           DN+D+ +A +  V V + PG+N+ +  E   +L+L L R ++PA+  + AG W   R   
Sbjct: 74  DNVDIPAASEHSVWVTSTPGSNSNAVAEHVFSLLLSLTRRIIPAANRVLAGTWAEGRGDL 133

Query: 461 TGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDP 571
            G EL+G+TL I+G      RVAT    FGM ++  DP
Sbjct: 134 VGFELSGRTLGIVGFGAIGKRVATIANGFGMRVLASDP 171


>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
           dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
           Putative D-3-phosphoglycerate dehydrogenase -
           Bradyrhizobium sp. (strain ORS278)
          Length = 335

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV++A ++G+ V  A GAN+ S  EL   LM  +AR +      +K G WD+A   G
Sbjct: 89  DNIDVEAADRRGIPVFVARGANSQSVAELAFALMFAVAREIPHLDARIKTGHWDKATTKG 148

Query: 467 SELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFDPF 574
           ++L G++L ++G     R+   +     M +  FDP+
Sbjct: 149 AQLLGRSLGVIGFGEIGRILVGLVQPLHMEVRIFDPY 185


>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
           Epsilonproteobacteria|Rep: D-3-phosphoglycerate
           dehydrogenase - Sulfurovum sp. (strain NBC37-1)
          Length = 529

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 38/98 (38%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-WDRALYT 463
           DN+D+  + K+G+ V+N P AN ++A ELT   ML   R    A   LK  R W R  + 
Sbjct: 80  DNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYAHNNLKLDRVWRRQDWY 139

Query: 464 GSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
           G+EL  K L I+G      RV  R  AF M+++ +DP+
Sbjct: 140 GTELKDKKLGIIGFGNIGSRVGKRAKAFEMDVLAYDPY 177


>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase
           NAD-binding - Sinorhizobium medicae WSM419
          Length = 310

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 39/99 (39%), Positives = 59/99 (59%), Gaps = 2/99 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA-LKAGRWDRALYT 463
           DN+ +    ++G+G++ A GANA+   EL+  LML   RH +PA TA ++AG W R+   
Sbjct: 82  DNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAALRH-IPAETAGIRAGGWPRS--R 138

Query: 464 GSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPFR 577
           G E+A +T+ I+G      RVA  + A   ++I  DPFR
Sbjct: 139 GREIAERTVGIIGCGAIGKRVARAVSAMRASVIACDPFR 177


>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
           n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
           putative - Thermotoga maritima
          Length = 327

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 41/105 (39%), Positives = 60/105 (57%), Gaps = 2/105 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYT 463
           DNID+++A KKG+ V    GAN+LS  ELT   +  L+R +V A   L    RW+  +  
Sbjct: 74  DNIDLEAATKKGIPVTITAGANSLSVAELTIAFIFALSRGLVWAHNKLFLERRWEGTV-- 131

Query: 464 GSELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPFRVC*SVR 595
           G E++GKTL ++G     R V  +    GMN++ +DP+    SVR
Sbjct: 132 GQEVSGKTLGVVGFGSIGREVVKKAVCLGMNVLVYDPYVSKDSVR 176


>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
           Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
           Bacillus clausii (strain KSM-K16)
          Length = 316

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 37/97 (38%), Positives = 56/97 (57%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDVD+A K GV V N P AN  +  +   +L+L LAR +   +   K G+W  +L+ G
Sbjct: 79  DNIDVDAAKKHGVTVTNVPNANKHAVADFAFSLLLSLARQIPTGNEKTKKGKWP-SLF-G 136

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
           +++  +TL I+GL      VA R   F M ++ +DP+
Sbjct: 137 ADVYQQTLGIIGLGAIGKEVARRASGFSMTVLAYDPY 173


>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
           RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Roseiflexus sp. RS-1
          Length = 323

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 37/97 (38%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +A K+G+ VIN P     S  E    L+L LA+ VV +   L+   W  A   G
Sbjct: 80  DNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVVASDRVLRTEGWRAARLRG 139

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
            E+ GKTL I+GL   GR          GM+++ +DP
Sbjct: 140 IEVRGKTLGIVGLGRIGRRVAQICRQGLGMHVVAYDP 176


>UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2;
           Burkholderiales|Rep: D-3-Phosphoglycerate dehydrogenase
           - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
           / Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
           H16 / DSM 428 / Stanier337))
          Length = 360

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 40/98 (40%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           D ID+D+  + GV V+N  G NA S  E+T  LML + R +  +  +L+A   + R    
Sbjct: 96  DTIDIDACTEAGVAVLNQAGGNADSVAEMTLGLMLAVLRRIAESDRSLRAHNCESREDLM 155

Query: 464 GSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
           G EL G+TL ++G+   GR RVA    A GM +IG DP
Sbjct: 156 GHELRGRTLGLVGVGHAGR-RVAALGRALGMRVIGCDP 192


>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
           dehydrogenase - Rhizobium sp. (strain NGR234)
          Length = 327

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 39/97 (40%), Positives = 58/97 (59%), Gaps = 3/97 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-ALYT 463
           D+ID D+A + GVG+   PG NA +  + T  ++L L R VV    A+KAGRWDR    T
Sbjct: 82  DSIDHDAAKEFGVGISVTPGMNAETVADQTLAMILGLMRRVVTQDQAVKAGRWDRVGEAT 141

Query: 464 GSELAGKTLAIL--GLTGRPRVATRMYAFGMNIIGFD 568
            +EL  KT+ ++  G+ G+  V  R+  FG+ ++ FD
Sbjct: 142 PTELYRKTVGLIGAGIIGK-AVIRRLLGFGVRVLYFD 177


>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic region:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding; n=6;
           Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic region:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
           eutropha (strain JMP134) (Alcaligenes eutrophus)
          Length = 312

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 39/97 (40%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 463
           DNIDV +   +G+ VI A GANA S  E   T   +L R     S  +  G+W RA L  
Sbjct: 78  DNIDVAACRDRGIRVIPASGANARSVAEYVVTTAALLLRGAYLGSAEVAGGKWPRARLSE 137

Query: 464 GSELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFDP 571
           G E  GKTL ++G     R A  +  AFGM ++  DP
Sbjct: 138 GREALGKTLGLIGFGDIGRQAAALAQAFGMRVVAHDP 174


>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
           n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
           Dimethylmenaquinone methyltransferase - Rhodobacter
           sphaeroides ATCC 17025
          Length = 334

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 31/97 (31%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +A  +G+ V+ + G+N+ +  E    L L+L + + P + A+K G W +  + G
Sbjct: 89  DNIDLAAAEARGIPVLRSMGSNSRAVAEHAIALALMLVKEIQPLNAAVKGGAWPKPTFIG 148

Query: 467 SELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFDPF 574
            +  G  L ++G  G  R   RM  A GM ++  DP+
Sbjct: 149 KDFQGAMLGLVGYGGIGRETARMAEALGMEVVVHDPY 185


>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD binding subunit; n=3;
           Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD binding subunit - Roseovarius sp.
           HTCC2601
          Length = 326

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 36/97 (37%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +  + G+ V N P ANA +  EL   LM  +AR +     ++ AG WDR +  G
Sbjct: 84  DNIDIPACTEAGLPVCNTPAANADAVAELAVGLMFSMARWIPQGHASVTAGGWDRRI--G 141

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
           ++L GKTL I+GL     R+A      GM ++  D +
Sbjct: 142 TQLGGKTLGIVGLGNIGKRLAKLARGLGMQVVATDKY 178


>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
           DSM 2379|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Pelobacter propionicus
           (strain DSM 2379)
          Length = 357

 Score = 65.7 bits (153), Expect = 8e-10
 Identities = 31/93 (33%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DV+ A K+GV ++  P  +A +  E+    ML L+R ++ A  +++ GRW++  ++G
Sbjct: 97  DNLDVEYARKRGVQLVRIPQPSARAVAEMAFAFMLALSRRLLEADRSMRNGRWEKHEFSG 156

Query: 467 SELAGKTLAILGLTGRPRVATRM-YAFGMNIIG 562
             L  KTL ++G+        +M  A+GM +IG
Sbjct: 157 YLLRDKTLGVVGIGNTGSCVAQMGVAWGMRVIG 189


>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase family protein; n=41; cellular
           organisms|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase family protein - Bacillus anthracis
          Length = 323

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 40/102 (39%), Positives = 53/102 (51%), Gaps = 5/102 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 457
           DNID   AG+KG+ V N P  +  +  ELT  L+L  AR +    T  +      W    
Sbjct: 77  DNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRIPEGDTLCRTTGFNGWAPLF 136

Query: 458 YTGSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPFR 577
           + G E+ GKT+ I+GL   G+  VA R  AFGMNI+   P R
Sbjct: 137 FLGREVHGKTIGIIGLGEIGK-AVAKRAKAFGMNILYTGPNR 177



 Score = 32.7 bits (71), Expect = 7.0
 Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
 Frame = +3

Query: 108 ELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           ELL  + +    K + IS +EL   + + DAL+   +T+VTKEV+DA
Sbjct: 16  ELLKDHDVEMYDKEELISLDELTERVKDKDALLSLLSTKVTKEVIDA 62


>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic region:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding; n=2;
           Thermoanaerobacter ethanolicus|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, catalytic region:D- isomer
           specific 2-hydroxyacid dehydrogenase, NAD-binding -
           Thermoanaerobacter ethanolicus ATCC 33223
          Length = 319

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 37/95 (38%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+IDV +A + G+ V NAPG N+    +L   L+ +LAR +  A+T  K G+W + +  G
Sbjct: 84  DSIDVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTDTKNGKWIKPV--G 141

Query: 467 SELAGKTLAILGL-TGRPRVATRMYAFGMNIIGFD 568
             L+ KT+ I+G+ T    VA R   + MNI+G+D
Sbjct: 142 ISLSKKTIGIIGVGTIGTAVAKRATGYDMNILGYD 176


>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
           Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
           reductase - Fervidobacterium nodosum Rt17-B1
          Length = 317

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 35/103 (33%), Positives = 61/103 (59%), Gaps = 5/103 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
           +NID+++A ++G+ V N PG    +  ++   L+L +AR +V +   ++ G+   W   L
Sbjct: 77  NNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVARRIVESDKFVREGKFVGWKPKL 136

Query: 458 YTGSELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPFRV 580
           + G +L GKTL ++G+ GR    VA R   FGMNI+ ++  R+
Sbjct: 137 FLGYDLYGKTLGVIGM-GRIGQAVARRALGFGMNIVYYNRNRL 178


>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
           HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
          Length = 522

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 33/97 (34%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + ID+  A  K + V+N PGAN+ +  E    +M+  AR  +    + +AG W +A   G
Sbjct: 76  NTIDIQYARSKDITVMNTPGANSNAVAEEAVGMMISCARFFIEGDRSTRAGEWKKAQLQG 135

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
            EL GKT+ I G     + +A R+  F ++I+ +DPF
Sbjct: 136 FELTGKTVGIAGFGNIGQLLAKRLSGFEVDILVYDPF 172


>UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6;
           Alphaproteobacteria|Rep: Putative uncharacterized
           protein - Roseobacter sp. SK209-2-6
          Length = 166

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 38/81 (46%), Positives = 42/81 (51%)
 Frame = -3

Query: 501 PRMARVLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITPT 322
           P   RVL  SS+P+    SHLPA+   EA   WRA  NI     S  +  L  G  IT T
Sbjct: 4   PMTPRVLLVSSVPMNLDFSHLPAWVEAEASGIWRATANIIAMACSAVVIILPNGVFITIT 63

Query: 321 PFLPAESTSMLSTPAPARPTT 259
           P L A S SMLS P PAR  T
Sbjct: 64  PRLEAASLSMLSVPMPARAMT 84


>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
           Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
           Lactobacillus plantarum
          Length = 392

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 37/106 (34%), Positives = 58/106 (54%), Gaps = 10/106 (9%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST---------ALKAG 439
           +NI +D A   G  V N PG+NA +  EL   L+++ +R+++ A+T           +  
Sbjct: 60  NNIPIDQATANGTAVFNTPGSNANAVKELIIGLLIMASRNLIAATTYSAQHTEADISQRT 119

Query: 440 RWDRALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
             D+  + G EL GKTLA++GL      VA    + GMN+IG+DP+
Sbjct: 120 EHDKTQFNGIELTGKTLAVIGLGHVGALVANAALSLGMNVIGYDPY 165


>UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE
           DEHYDROGENASE SERA2; n=11; Mycobacterium|Rep: POSSIBLE
           D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA2 - Mycobacterium
           tuberculosis
          Length = 326

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 34/103 (33%), Positives = 57/103 (55%), Gaps = 7/103 (6%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR------ 451
           N+D+  A   G+ V++ P  NA +  E+T  L+L +ARH++PA   +++G   R      
Sbjct: 86  NVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADADVRSGNIFRDGTIPY 145

Query: 452 ALYTGSELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPFR 577
             + G+E+AG T  ++GL    R V  R+   G+ +I  DP+R
Sbjct: 146 QRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPYR 188


>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
           specific 2-hydroxyacid dehydrogenase NAD-binding -
           Anaeromyxobacter sp. Fw109-5
          Length = 399

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 33/95 (34%), Positives = 56/95 (58%), Gaps = 2/95 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + IDV +A ++GV V N PG N+++  EL   L++ L R +      L+AG+WD+  ++ 
Sbjct: 74  NTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVALDRRIPDNVALLRAGKWDKKTFSE 133

Query: 467 SE-LAGKTLAILGLTGRPR-VATRMYAFGMNIIGF 565
           ++ L G+TL + G+    R VA R  A GM ++ +
Sbjct: 134 AQGLYGRTLGVAGVGSIGREVARRAQALGMRVVAW 168


>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
           Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
           Sulfolobus solfataricus
          Length = 326

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 38/100 (38%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID + A K+ + ++ APGA+  SA ELT  L++  AR +  +    K G + +    G
Sbjct: 92  DNIDTEEASKRNIKIVYAPGASTDSAAELTIGLLIAAARKLYDSMNMAKGGIFKK--IEG 149

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPFRV 580
            ELAGKT+ I+G  GR   +VA    A  MN+I +D   +
Sbjct: 150 IELAGKTIGIVGF-GRIGTKVAKVCKALDMNVIAYDVINI 188



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 26/65 (40%), Positives = 36/65 (55%)
 Frame = +3

Query: 57  VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 236
           +D K VLI D V       L   G+    K +I++EELL  I  +  L+VRS T+V KE+
Sbjct: 16  LDFK-VLITDPVDQYMIRTLQNNGLIVDYKPEITREELLKIIDQYQVLIVRSRTKVDKEI 74

Query: 237 LDAGV 251
           +  GV
Sbjct: 75  IRYGV 79


>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Pseudomonas fluorescens (strain PfO-1)
          Length = 324

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 40/99 (40%), Positives = 53/99 (53%), Gaps = 4/99 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 460
           DN+D  +A + GV V N PGAN  S  E    L+L ++R V  A+   +   W  DR   
Sbjct: 74  DNVDYKAAAELGVWVTNTPGANRRSVVEHVFALLLGISRKVQLATDQTRNNIWAQDRLSL 133

Query: 461 TGSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
           TG EL G+TL ++G    GR  VA    AFGM ++  DP
Sbjct: 134 TGIELEGRTLGLIGFGDIGR-HVAPVAEAFGMKVLATDP 171


>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
           Leuconostoc mesenteroides subsp. mesenteroides ATCC
           8293|Rep: Lactate dehydrogenase related enzyme -
           Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 314

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 34/99 (34%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           D +DVD+A ++G+ V+N P A + S  E   + +L +++++   S A+    W+ R  + 
Sbjct: 76  DAVDVDAATQRGIYVVNTPKALSGSVAETAVSELLAISKNLYQDSKAIHDDNWNYRKAHP 135

Query: 464 GSELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
           G ++ GKT+ ILG  GR   +VA ++  F + +I FDPF
Sbjct: 136 GRDIEGKTVGILGF-GRIGQQVAKKLSGFDVKVIAFDPF 173


>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
           Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
           Lactococcus lactis subsp. cremoris (strain SK11)
          Length = 398

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 37/108 (34%), Positives = 61/108 (56%), Gaps = 12/108 (11%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRAL-- 457
           +NI ++    KG+ V NAPG NA +  EL  ++M+   R++ PA+  L   +  D+A+  
Sbjct: 64  NNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNLKPANKWLTGQKGNDKAIDV 123

Query: 458 --------YTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
                   ++GSE++GKTL ++GL     +VA      GM +IG+DP+
Sbjct: 124 AVENGKKAFSGSEISGKTLGVIGLGNIGSKVANDAQRLGMKVIGYDPY 171


>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
           Bordetella|Rep: Putative dehydrogenase - Bordetella
           bronchiseptica (Alcaligenes bronchisepticus)
          Length = 330

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 34/96 (35%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
 Frame = +2

Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG-S 469
           ID+ +A + G+ V+N PGANA S  EL   + + L +  VP   A++ G W+     G  
Sbjct: 81  IDLAAAERLGIPVVNTPGANARSVAELALAMAMALLKRTVPLDQAVRQGNWNIRYEAGLR 140

Query: 470 ELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
           EL+G +L I+G    GR   A  +  FGM +  + P
Sbjct: 141 ELSGMSLGIVGFGQIGRALAAMAIGGFGMRVHVYSP 176


>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
           palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Rhodopseudomonas palustris
           (strain BisB18)
          Length = 321

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 37/98 (37%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           ++ID+ +A   GV V+ A GANA S  E    LML L + V      ++ G WD+  Y G
Sbjct: 81  NDIDLAAAKALGVPVLAAVGANAHSVAEHAFMLMLALIKDVRNQDAYVRGGGWDKKGYRG 140

Query: 467 SELAGKTLAI--LGLTGRPRVATRMYAFGMNIIGFDPF 574
            EL G+ L +  +G+ GR  +A  +   GM  I +DPF
Sbjct: 141 RELRGRVLGLVGIGMIGR-ALAAMVQPIGMTTIAYDPF 177


>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
           DSM 13941|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
           13941
          Length = 345

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 35/97 (36%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +A ++G+ VIN P     S  E    L+L LA+ VV A    +   W  A   G
Sbjct: 81  DNIDLAAATERGILVINTPDGPTESTAEHAVALVLALAKQVVAADHRFRTAGWSAARLRG 140

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
            E+ GKTL ++GL   GR          GM +  +DP
Sbjct: 141 VEVRGKTLGVVGLGRIGRRVAQICRQGLGMRVAAYDP 177


>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
           TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
           NAD-binding - Opitutaceae bacterium TAV2
          Length = 318

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 2/96 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D IDV  A  K + V+  PG N  +  E T  L+L L ++++  + + ++G W R   TG
Sbjct: 81  DKIDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLALEKNILFHTDSTRSGGWKRK--TG 138

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFD 568
            EL  KT+ I+GL GR    VA R  AFGM +I +D
Sbjct: 139 HELLAKTIGIVGL-GRIGKEVAIRARAFGMEVIAYD 173


>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
           putative; n=2; Filobasidiella neoformans|Rep:
           D-3-phosphoglycerate dehydrogenase 2, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 508

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 30/95 (31%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + +D++ A K+G+ V N+P +N+ S  EL  + ++ L+R ++  +  ++AG W++     
Sbjct: 174 NQVDLEHAAKRGIAVFNSPFSNSRSVAELVISEIIALSRQIIDRTHEMRAGIWNKLSKNC 233

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFD 568
            E+ GKTL I+G      +++    AFGM++I FD
Sbjct: 234 WEIRGKTLGIVGYGHIGSQLSVLAEAFGMSVIYFD 268



 Score = 41.9 bits (94), Expect = 0.011
 Identities = 20/60 (33%), Positives = 40/60 (66%), Gaps = 2/60 (3%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           +L+++ +    A+ L + G  +   TKA  ++EEL+ ++PN+ A+ +RS T++T +V+DA
Sbjct: 101 ILLLENINLDAADYLKSQGYEVDHVTKA-YTEEELIAKLPNYHAIGIRSKTKITAKVIDA 159


>UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|Rep:
           Glycerate dehydrogenase - Uncultured methanogenic
           archaeon RC-I
          Length = 319

 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 35/96 (36%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D++D+D+A  KGV V NAPG +  +  E    ++L   R +  A   ++  ++D   + G
Sbjct: 77  DDVDLDAATLKGVAVANAPGYSNEAVAEHVFAMLLSFIRRISEADFWIREEKFDCTAFEG 136

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFD 568
            EL GKT+ I+G TG+   RVA     FGM++I +D
Sbjct: 137 RELRGKTMGIIG-TGQIGLRVAEIARCFGMDVIAYD 171


>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
           Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
           Cenarchaeum symbiosum
          Length = 310

 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 38/96 (39%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +A   GV VINA      +  EL   +ML +AR +  A   ++ G+W +    G
Sbjct: 79  DNIDLAAAESAGVRVINAVEGATTAVSELVLGMMLCMARQIPRADRGIRGGKWLKGELGG 138

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFD 568
           +EL GK L I+GL   GR R+        MNIIG D
Sbjct: 139 TELKGKYLGIVGLGNIGR-RLGRLARGMNMNIIGHD 173



 Score = 40.7 bits (91), Expect = 0.026
 Identities = 19/58 (32%), Positives = 32/58 (55%)
 Frame = +3

Query: 66  KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 239
           ++VLI D        +L   G+  + K +I+ EEL  E P +  ++VRS T +T E++
Sbjct: 5   ETVLICDKADPVLGRILQQNGLRVSYKPEITPEELAAEAPGYSIIIVRSRTTITGEII 62


>UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15;
           Viridiplantae|Rep: Glycerate dehydrogenase - Cucumis
           sativus (Cucumber)
          Length = 382

 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 36/102 (35%), Positives = 56/102 (54%), Gaps = 5/102 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
           +N+DV++A K GV V N PG    +  EL  +L L  AR +V A   ++AGR+D     L
Sbjct: 98  NNVDVNAANKYGVAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNL 157

Query: 458 YTGSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPFR 577
           + G+ L G+T+ ++G    G       +  F MN+I FD ++
Sbjct: 158 FVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQ 199


>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
           Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
           - Rhodococcus sp. (strain RHA1)
          Length = 325

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 36/97 (37%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV  A + GV V+   GANA+S  E T  + L   R  V      + G W+R    G
Sbjct: 83  DNIDVKCANEAGVVVVAPLGANAISVAEHTIGMALAAVRRTVELDADCRRGGWERT--PG 140

Query: 467 SELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFDPF 574
            EL G    +LG     R   R+  + GM+I+ +DPF
Sbjct: 141 RELHGGVWGLLGAGATGRACARLARSLGMSIVAYDPF 177


>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
           Bacillus sp. SG-1|Rep: Putative uncharacterized protein
           - Bacillus sp. SG-1
          Length = 322

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 34/99 (34%), Positives = 57/99 (57%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           DNID+++A  +G+ V NAP AN  +  E   TL+L  +R ++   +AL+ G ++ R    
Sbjct: 76  DNIDLEAASDRGILVTNAPFANVNAVAEHVLTLILSGSRQLIQVDSALRNGDFEVRNRKF 135

Query: 464 GSELAGKTLAILGLTGRPRVATRM--YAFGMNIIGFDPF 574
           G EL GKTL ++G     ++      Y  GM+++ +DP+
Sbjct: 136 GIELKGKTLGVVGFGNIGQLVAEKCHYGLGMDVLVYDPY 174


>UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388;
           n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
           protein PH1388 - Pyrococcus horikoshii
          Length = 119

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 41/93 (44%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
 Frame = -3

Query: 486 VLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITPTPFLPA 307
           VLP+SS+P+    +H P+   + A   + A  NIN   SS  L  LA GAL T  PF  A
Sbjct: 5   VLPSSSIPIASFFAHTPSLIFLSAKAIFLATENINPTASSATLLELAAGALTTSIPFSLA 64

Query: 306 ESTSMLSTPAPARPTTFT-SRLRPTPLWSLELL 211
            STSMLS P PA   T +   L  T L +L LL
Sbjct: 65  ASTSMLSKPTPALAITLSFGALSITLLVTLGLL 97


>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
           Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
           symbiosum
          Length = 348

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 40/97 (41%), Positives = 53/97 (54%), Gaps = 6/97 (6%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 457
           D+IDV  A  +G+ V   P     +  +LT  LML L R V      ++AGRW +     
Sbjct: 113 DHIDVAHARGRGITVGYTPDVLTDATADLTMALMLDLLRRVTEGDRIIRAGRWRQIYGAD 172

Query: 458 -YTGSELAGKTLAILGLTGR--PRVATRMYAFGMNII 559
            Y G+++ GKTL ILG+ GR   RVA R  AFGM +I
Sbjct: 173 DYLGTDVGGKTLGILGM-GRIGSRVAKRAAAFGMKVI 208


>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep:
           D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
           erythraea (strain NRRL 23338)
          Length = 336

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 36/93 (38%), Positives = 54/93 (58%), Gaps = 3/93 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + ID +SA ++GV V N PG NA++  EL   LML L R V      L+AGRWD+  Y+ 
Sbjct: 74  NTIDCESAAERGVHVCNVPGRNAIAVAELAFALMLALDRSVCDNVDDLRAGRWDKKRYSR 133

Query: 467 SE-LAGKTLAILGLTGRPRV--ATRMYAFGMNI 556
           +  + G+ + ++GL G+  +  A R  AFG  +
Sbjct: 134 ARGIHGRRVGVVGL-GQIGLAFAERAAAFGATV 165


>UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=14; Bacteria|Rep: D-isomer
           specific 2-hydroxyacid dehydrogenase, NAD-binding -
           Arthrobacter sp. (strain FB24)
          Length = 322

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 41/96 (42%), Positives = 57/96 (59%), Gaps = 2/96 (2%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 469
           +ID+ +A + G+ V+   G +  +A ELT  L+L LAR +      L+ GRW   +  G 
Sbjct: 84  SIDLRAAEELGI-VVCGTGGSPTAAPELTWGLLLALARSISFEDRNLREGRWQSTV--GF 140

Query: 470 ELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
           ELAGKTL +LGL   GR RVA    AFGM++I + P
Sbjct: 141 ELAGKTLGVLGLGKIGR-RVAAYGQAFGMDVIAWSP 175


>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
           putative; n=1; Saccharopolyspora erythraea NRRL
           2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
           Saccharopolyspora erythraea (strain NRRL 23338)
          Length = 352

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 5/100 (5%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY--- 460
           N+D+ +A + GV V  APG NA +A E    L+L   R +  +   LK+G W    Y   
Sbjct: 100 NVDLQAATEAGVVVSYAPGRNAAAAAEFAVGLVLAALRRIPASDAELKSGNWRGDYYAYE 159

Query: 461 -TGSELAGKTLAILGLTGRPRVATR-MYAFGMNIIGFDPF 574
             G EL G T+ ++G     R+  R + AFG +++  DPF
Sbjct: 160 NAGIELEGSTVGLVGYGAIGRIVARVLAAFGAHVLVADPF 199


>UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase; n=2; Burkholderia|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 312

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 31/91 (34%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +N+DV +A ++G+ V +APG NA +  +    ++L LAR   P + A++AGRW  +    
Sbjct: 77  ENVDVAAAARRGIVVAHAPGTNASTVADHAIGMLLALARGYAPLTGAVRAGRWHASRAAR 136

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNI 556
             L G  L ++G+    R VA R   F M +
Sbjct: 137 PTLTGAALGVIGMGRIGRLVAARAQGFDMTL 167


>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Acidovorax sp.
           JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Acidovorax sp. (strain JS42)
          Length = 339

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+ID+++  K+G+ V + P   + S  E    L+L + RH+  A    + G +     TG
Sbjct: 83  DHIDLEACRKRGIAVCHVPDYGSASVAEHAFALLLGVTRHLTQAHERARQGSFAYRGLTG 142

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
            EL G+TL I+GL   GR  VA     FGM+++ +DP
Sbjct: 143 FELEGRTLGIVGLGRIGR-HVARIAVGFGMDVLAYDP 178


>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
           ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Thermoanaerobacter
           ethanolicus X514
          Length = 324

 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 35/99 (35%), Positives = 55/99 (55%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           DNIDV++A +KG+ V N P  N LS  E T  ++L L++ +     A+++G W  R    
Sbjct: 75  DNIDVNAATEKGILVCNLPAVNNLSVAEHTIAMILNLSKQLSLMDKAVRSGNWGARNSNI 134

Query: 464 GSELAGKTLAILGLTG-RPRVATRMY-AFGMNIIGFDPF 574
             E+ GK L I+G+      VA + +   GM I+ +DP+
Sbjct: 135 SVEIEGKVLGIVGMGNIGSLVAKKCHDGLGMKIVAYDPY 173


>UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium efficiens|Rep: Putative uncharacterized
           protein - Corynebacterium efficiens
          Length = 161

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 42/109 (38%), Positives = 47/109 (43%)
 Frame = -3

Query: 504 KPRMARVLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITP 325
           KP +  VLP  S P+   R H P+     A   WRA         S A   L  GAL T 
Sbjct: 4   KPTIPTVLPKISTPLKEERFHSPSRRVASAAGIWRAVDRSRETACSQAEWMLEVGALATM 63

Query: 324 TPFLPAESTSMLSTPAPARPTTFTSRLRPTPLWSLELLNAQPERRGWVS 178
           TP   A   S LS P PARPT F  RL    + S   L A+  RR   S
Sbjct: 64  TPASVAAGMSTLSRPTPARPTIF--RLGAAAMTSASTLVAERTRRASAS 110


>UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase family protein; n=8; Yersinia|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase family
           protein - Yersinia pestis (biovar Antiqua strain
           Nepal516)
          Length = 316

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 460
           DNID+ +A K+G+ + N P        +    + L LAR +      +++GRW  D+ + 
Sbjct: 77  DNIDLSAARKRGMRICNVPDYGIEEVADHAAAMTLALARKLGRYEAGIRSGRWEIDQMVD 136

Query: 461 TGSELAGKTLAILGLTGRPRV-ATRMYAFGMNIIGFDPF 574
               L   T+ ++GL    R  ATRM  FG  IIGFDP+
Sbjct: 137 GVRSLRDTTVGLIGLGRIARAYATRMAVFGCRIIGFDPY 175


>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
           RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Sphingomonas wittichii RW1
          Length = 317

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 36/96 (37%), Positives = 53/96 (55%), Gaps = 5/96 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
           D+ID+D+   +G+ + N PG  + +  +    L+L   R +  A+  L+ GRW     + 
Sbjct: 80  DHIDLDAVRARGLPMFNTPGILSNAVADQAMLLLLAATRRMAEATALLREGRWTDLWSSH 139

Query: 458 YTGSELAGKTLAILGL--TGRPRVATRMYAFGMNII 559
             G ELAG+TL I GL   GR RVA R  AFGM ++
Sbjct: 140 ILGVELAGRTLGIYGLGDIGR-RVARRATAFGMRLV 174


>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep:
           D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
           erythraea (strain NRRL 23338)
          Length = 322

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 35/97 (36%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D +D  +A ++G+ V N PG NA +  + T   ML L RH       ++ G W      G
Sbjct: 85  DGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLHLLRHYAAGHRKVEQGGWGPEGLRG 144

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
            +L+  T+AILG     R VA R+  FG  I+  DPF
Sbjct: 145 RDLSALTVAILGFGNIGRAVARRLDGFGAEIVVHDPF 181


>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
           / ATH 2.4.9)
          Length = 331

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 38/98 (38%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           D +D ++A +KGV V N PGANA S  EL   L L +AR +  A  AL+ G+   R    
Sbjct: 74  DPVDKEAAARKGVVVANTPGANARSVAELAVGLALAVARRIPAADRALREGKTGFRESAR 133

Query: 464 GSELAGKTLAILGLTGRPRVATRM--YAFGMNIIGFDP 571
            SEL G+T  ++G     R   RM   AF M ++   P
Sbjct: 134 FSELRGRTALVVGWGASGRETGRMLAQAFDMRLLVHSP 171


>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
           unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
          Length = 332

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+IDV  A  KG+ V N P     S  E    LML LAR +      ++ G +  +   G
Sbjct: 77  DHIDVAYANSKGITVCNVPSYGEESVSEYAIMLMLALARKLRETIDNVEKGVYKTSNLRG 136

Query: 467 SELAGKTLAILGLTGRPRVATRMYA--FGMNIIGFD 568
            ELAGKTL ++G TGR    T + A  FGM+++ +D
Sbjct: 137 IELAGKTLGVIG-TGRIGARTALLARCFGMDVVCYD 171


>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
           dehydrogenase and related dehydrogenases; n=1;
           Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
           dehydrogenase and related dehydrogenases -
           Brevibacterium linens BL2
          Length = 314

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+D+A + G+ V N PG N  +  EL   LML  AR +      +  G W R    G
Sbjct: 82  DNVDIDAAAELGIRVCNTPGVNHHAVAELALALMLACARRLNTVLAGVDDGGWPRE--AG 139

Query: 467 SELAGKTLAILGL-TGRPRVATRMYAFGMNII 559
           +EL GK+L ++G       +A    A GM ++
Sbjct: 140 TELRGKSLGVIGYGPSGKAIAALGVALGMRVL 171


>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
           specific 2-hydroxyacid dehydrogenase - Nitrosomonas
           europaea
          Length = 311

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 37/97 (38%), Positives = 53/97 (54%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+++A +  + V N P A A +  ELT  LML   R +     +++ G W R+   G
Sbjct: 83  DNVDLEAARRLNIQVSNTPEAPAQAVAELTLGLMLDCLRQINRIDRSVRQGEWPRS--QG 140

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
             LA +T+ I+GL   GR RVA    AFG  +I  DP
Sbjct: 141 RLLAARTVGIVGLGHIGR-RVAKLCQAFGAQVIAHDP 176


>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
           succiniciproducens MBEL55E|Rep: SerA protein -
           Mannheimia succiniciproducens (strain MBEL55E)
          Length = 326

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           D++DV +A + G+ V+ APG+N  S  E    LM   A+ +V +   ++ G +  R+ Y 
Sbjct: 76  DDVDVKTATELGIPVVIAPGSNTRSVAEHAFALMFACAKDIVRSDNEMRKGNFAIRSSYK 135

Query: 464 GSELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFDPF 574
             EL  KTLA++G      +  +M  A GMN+  +DPF
Sbjct: 136 AYELNHKTLALIGYGRIGSILAQMSKAIGMNVKVYDPF 173


>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
           specific 2-hydroxyacid dehydrogenase - Thiobacillus
           denitrificans (strain ATCC 25259)
          Length = 391

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 12/107 (11%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA-----------STALK 433
           +NI V    ++G+ V NAPGANA +  EL    ML+ AR++VPA               K
Sbjct: 64  NNIPVKKMSERGLPVFNAPGANANAVKELVIAGMLMGARNLVPALKFVESLDGTDEAMHK 123

Query: 434 AGRWDRALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDP 571
           A    +  + G EL G+TL ++GL      +A      GMN++G+DP
Sbjct: 124 ATEAGKKQFAGMELPGRTLGVIGLGAIGSHIAEAAIRLGMNVVGYDP 170


>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
           n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
           - Archaeoglobus fulgidus
          Length = 323

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 4/98 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 457
           +NIDV++A K  + V N  G NALS  E T    L L R ++ A  ++ +GRW++   A 
Sbjct: 82  NNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALLRRLIYAHNSVLSGRWEQDEMAN 141

Query: 458 YTGSELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFD 568
               EL GKT  I+G+  + R V  R+  +G+ II  D
Sbjct: 142 LGVYELHGKTWGIIGMGAQGREVTKRLQGWGVKIIYHD 179


>UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1;
           Streptomyces avermitilis|Rep: Putative glycerate
           dehydrogenase - Streptomyces avermitilis
          Length = 325

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 40/96 (41%), Positives = 54/96 (56%), Gaps = 5/96 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVIN--APGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRA 454
           D +D+D+A  +G+ V N  + GA   +  E T  LML LA+ +VPA TAL    W   R 
Sbjct: 82  DYVDLDAARARGLPVCNIGSSGAEQQNVAEQTFALMLALAKQLVPAHTALVDADWALPRL 141

Query: 455 LYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNII 559
             + +EL+GKTL I+GL      VA R  AF M I+
Sbjct: 142 QRSITELSGKTLGIVGLGHIGEEVARRAVAFDMRIV 177


>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Victivallis vadensis
           ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Victivallis vadensis ATCC
           BAA-548
          Length = 316

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 35/94 (37%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNI++  A +KG+   N PGA   S  E    ++L+ AR  + A+   + G W     TG
Sbjct: 77  DNINLPRAAEKGIYCTNTPGALEQSVAECAIGMILLAARQFIAAADDCRNGLWQP--QTG 134

Query: 467 SELAGKTLAIL--GLTGRPRVATRMYAFGMNIIG 562
            ELAGKTLA++  G  G    A     FGM++ G
Sbjct: 135 CELAGKTLAVIGCGAIGSRVAAIAKNGFGMSVTG 168


>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
           DSM 5348|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Metallosphaera sedula DSM
           5348
          Length = 324

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 4/98 (4%)
 Frame = +2

Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL---YT 463
           +D+ +A ++ + +   PG N+++  ELT  L + L R V+P + ++KAG+W         
Sbjct: 85  VDLKAAKERDIIITYNPGGNSVAVAELTIMLAIALYRKVIPLALSVKAGKWSELKPKDTM 144

Query: 464 GSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
           G EL GK   ILG      RVA  + +    ++G+DP+
Sbjct: 145 GHELEGKAWGILGFGNIGKRVAQLVTSLNCKVLGYDPY 182


>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
           Bacillaceae|Rep: Glycerate dehydrogenase -
           Oceanobacillus iheyensis
          Length = 314

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 34/98 (34%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID   A +KG+ V N PG NA +  +L   LML  AR++   +  L+ G W+  L  G
Sbjct: 81  DNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNIPAKNEELRNGNWE--LSMG 138

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPFR 577
            E+  K L I+G       +A R   F M ++ +  F+
Sbjct: 139 IEIFQKKLGIIGFGAIGQAIAQRATGFQMEVLAYGTFQ 176


>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Acidovorax sp. (strain JS42)
          Length = 337

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+ID+D     G+ V N P     +  E    L+L ++RH+V  +   + G + +    G
Sbjct: 76  DHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLAVSRHIVTGAERTRRGDFSQHGLRG 135

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            EL GKTL +LG TGR   RV      FGM I+ +D F
Sbjct: 136 FELRGKTLGVLG-TGRIGRRVIEIGKGFGMKIVAYDLF 172


>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
           Bacteria|Rep: Glycerate dehydrogenase - Geobacter
           sulfurreducens
          Length = 327

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 38/102 (37%), Positives = 55/102 (53%), Gaps = 7/102 (6%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW----DRA 454
           +N+DV++AGK+G+ V N P  +  S  + T  L+L LA HV    +A+KA  W    D +
Sbjct: 81  NNVDVEAAGKRGIPVANIPAYSTESVVQTTFALLLELAVHVGIHDSAVKAREWVRSPDHS 140

Query: 455 LYTGS--ELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFDP 571
            +     EL G TL I+G     R   R+  AFGM I+ + P
Sbjct: 141 FWKTPIVELDGLTLGIVGYGTIGRAVARVGAAFGMKIMAYAP 182


>UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillus
           subtilis
          Length = 344

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 7/102 (6%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR------ 451
           N+DV +A K+G+ V   PG NA +  E+    ++   RH   ++  LK G WD       
Sbjct: 94  NVDVAAASKRGIPVFYTPGRNAQAVAEMFIGNVISFLRHTSASNQWLKDGEWDSDYLQAY 153

Query: 452 ALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
             + G+EL GKT+ ++G      R+A  + AF   I  +DP+
Sbjct: 154 VKFKGNELTGKTVGMIGFGAVGQRIAKLLTAFDCKIKYYDPY 195


>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
           dehydrogenase; n=1; Klebsiella pneumoniae subsp.
           pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
           dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
           MGH 78578
          Length = 342

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 47/123 (38%), Positives = 61/123 (49%), Gaps = 28/123 (22%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR--------- 442
           NID  +A  +G+ V+  PG NA +A ELT  LML LARH+  +  ALK G          
Sbjct: 79  NIDTQAAQARGIRVLYTPGRNADAAAELTLGLMLSLARHIPQSHAALKRGEFTQADNASA 138

Query: 443 -----------WDRA------LYTGSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGF 565
                      WD +      ++ GSEL  KTL ++G    GR RVA    AFGM ++  
Sbjct: 139 ATQQGLRRDVVWDVSPESPYEVFKGSELRNKTLGLVGYGNIGR-RVARIARAFGMAVLVV 197

Query: 566 DPF 574
           DPF
Sbjct: 198 DPF 200


>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
           Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
           - Pedobacter sp. BAL39
          Length = 309

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 1/98 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID   A ++ + +INAP  N  +  E    LML L  +   A   ++ G+WDR    G
Sbjct: 78  DNIDEAVALERNIHLINAPEGNMDAVGEHAVGLMLSLMNNFRNADMEIRKGKWDREGNRG 137

Query: 467 SELAGKTLAILGLTGR-PRVATRMYAFGMNIIGFDPFR 577
            EL GKT+ I+G       +A ++  FG+ +I +D ++
Sbjct: 138 YELKGKTVGIIGYGFMGSSLARKLSGFGVQVIAYDKYK 175


>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
           Lmo2824 protein - Listeria monocytogenes
          Length = 395

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 11/107 (10%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK----------A 436
           +NI V++  +KG+ V N PGANA +  EL    + V AR ++  +  +K           
Sbjct: 61  NNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVKELPAEDDVEQK 120

Query: 437 GRWDRALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
               +  + G+ELAGK L I+GL      VA    + GM+++G+DPF
Sbjct: 121 VEAGKKAFAGTELAGKKLGIIGLGAIGALVANDALSLGMDVVGYDPF 167


>UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related
           dehydrogenases; n=8; cellular organisms|Rep: Lactate
           dehydrogenase and related dehydrogenases -
           Thermoanaerobacter tengcongensis
          Length = 358

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 39/99 (39%), Positives = 53/99 (53%), Gaps = 4/99 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSA-CELTCTLMLVLARHVVPASTALKAGRW-DRALY 460
           D ID++SA KKG  V    G     A  E    L+L + R V  AS  +K G+W +RA +
Sbjct: 106 DAIDIESATKKGTIVTIVEGIVEREAVAENAVALLLDVMRKVREASIKVKEGKWHERANF 165

Query: 461 TGSELAGKTLAILGLTG-RPRVATRM-YAFGMNIIGFDP 571
            G E+ GKT  I+G+     RVA  + Y FG  +I +DP
Sbjct: 166 IGYEIKGKTAGIIGIGNIGSRVAEILKYGFGAEVIAYDP 204


>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
           reductase; n=2; Thermus thermophilus|Rep: Glycerate
           dehydrogenase/glyoxylate reductase - Thermus
           thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
          Length = 338

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 33/96 (34%), Positives = 54/96 (56%), Gaps = 5/96 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 457
           D++D+++A ++G+ V + PG    +  +LT  L+L +AR VV  +   + G    W   L
Sbjct: 104 DHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARRVVEGAAYARDGLWRAWHPEL 163

Query: 458 YTGSELAGKTLAILGLTGR--PRVATRMYAFGMNII 559
             G +L G TL ++G+ GR    VA R  AFGM ++
Sbjct: 164 LLGLDLQGLTLGLVGM-GRIGQAVAKRALAFGMRVV 198


>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
           Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
           Gluconobacter oxydans (Gluconobacter suboxydans)
          Length = 416

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + +D+++A   G+ V NAP +N  S  EL    +++L R +   S A   G WD++    
Sbjct: 88  NQVDLNAARMLGIPVFNAPFSNTRSVAELVMGEIVMLLRRIPSRSEACHKGGWDKSATNA 147

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFD 568
            E+ GKTL I+G      +++    AFGM ++ FD
Sbjct: 148 WEVRGKTLGIVGYGSIGSQLSVLAEAFGMRVLYFD 182


>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
           BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Mesorhizobium sp. (strain BNC1)
          Length = 342

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 38/103 (36%), Positives = 56/103 (54%), Gaps = 6/103 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D ID++ A ++GV V    G+NA +  E T  L+L   R +  A  +++ G+W   +YT 
Sbjct: 84  DKIDLEGAERQGVYVAITAGSNAGAVAEHTIMLILAALRRLALADQSMREGKW---IYTE 140

Query: 467 -----SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPFR 577
                 +L+GKT+ ILG     R VA R+  F + II  DPFR
Sbjct: 141 LRPLCRKLSGKTVGILGFGNIGRNVAQRLQGFDVEIIYHDPFR 183


>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
           dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
           mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
           related dehydrogenase - Leuconostoc mesenteroides subsp.
           mesenteroides (strain ATCC 8293 /NCDO 523)
          Length = 312

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 37/97 (38%), Positives = 56/97 (57%), Gaps = 6/97 (6%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNI V+SA K GV V N PGANA++  EL  TL+L + R V  A+ +++ G    AL   
Sbjct: 77  DNIPVESATKHGVWVTNTPGANAIAVAELAVTLILTVLRKVNQATNSVQKG---EALTYP 133

Query: 467 SELAGKTLA--ILGLTGRPRVATR----MYAFGMNII 559
           + L G  L+  I+GL G  ++A      ++ FG +++
Sbjct: 134 ASLMGHNLSGKIIGLIGYGQIAQNLEKILHGFGAHVL 170


>UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genome
           shotgun sequence; n=3; core eudicotyledons|Rep:
           Chromosome chr3 scaffold_8, whole genome shotgun
           sequence - Vitis vinifera (Grape)
          Length = 418

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 33/102 (32%), Positives = 55/102 (53%), Gaps = 5/102 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
           +N+DV++A K GV V N PG    +  EL  +L +  AR +V A   ++AG +D     L
Sbjct: 98  NNVDVNAANKYGVAVGNTPGVLTETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHL 157

Query: 458 YTGSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPFR 577
           + G+ L G+T+ ++G    G       +  F MN+I +D ++
Sbjct: 158 FVGNLLRGQTVGVIGAGRIGSAYARMMVEGFKMNLIYYDLYQ 199


>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
           organisms|Rep: Glyoxylate reductase - Pyrococcus
           horikoshii
          Length = 334

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 9/106 (8%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR----- 451
           DNID++ A K+G+ V N P     +  +L   L+L  ARHVV     +++G W +     
Sbjct: 79  DNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVKGDRFVRSGEWKKRGVAW 138

Query: 452 --ALYTGSELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPFR 577
               + G ++ GKT+ I+GL GR    +A R   F M I+ +   R
Sbjct: 139 HPKWFLGYDVYGKTIGIIGL-GRIGQAIAKRAKGFNMRILYYSRTR 183


>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
           Staphylococcus saprophyticus subsp. saprophyticus ATCC
           15305|Rep: Putative dehydrogenase - Staphylococcus
           saprophyticus subsp. saprophyticus (strain ATCC 15305
           /DSM 20229)
          Length = 318

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 4/99 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 457
           +N+D+D A ++ + V N P A+  S  ELT  L+L +AR +       +      W    
Sbjct: 79  NNVDIDYARQQNIDVTNTPKASTNSTAELTFALVLAVARRIPEGDKLCRTTGFDGWAPLF 138

Query: 458 YTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDP 571
           + G E++GKT+ I+GL      VA R  AF MNI+   P
Sbjct: 139 FRGREVSGKTIGIIGLGEIGSAVARRAKAFDMNILYTGP 177


>UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
           TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
           NAD-binding - Opitutaceae bacterium TAV2
          Length = 355

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D  +  + G+ + N PG       ++    ++ LAR        +KAG W ++   G
Sbjct: 125 DNVDFAACQRLGLPISNTPGMFGREVADVAVGYVIALARQTFAIDRTVKAGGWIKS--AG 182

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
             LAGKT+A+ G    GR   A R++A  M I+ +DPF
Sbjct: 183 ISLAGKTVALAGFGDIGR-NTARRLFAAEMKIVAYDPF 219


>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
           enterocolitica subsp. enterocolitica 8081|Rep: Putative
           oxidoreductase - Yersinia enterocolitica serotype O:8 /
           biotype 1B (strain 8081)
          Length = 338

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 45/118 (38%), Positives = 61/118 (51%), Gaps = 23/118 (19%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK-----------A 436
           NIDV++A ++G+ V+  PG N+ +A ELT  LML LARH+  A +ALK           A
Sbjct: 79  NIDVNAATERGIPVVYTPGRNSDAAAELTIALMLNLARHIPQAHSALKQRQFTATTPGNA 138

Query: 437 GR-----WD------RALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
           G      WD        ++ G EL  KTL I+G      RV     AFGM ++  DP+
Sbjct: 139 GLKTDVVWDVTKDSPYEVFKGVELRNKTLGIVGYGSIGQRVGRIARAFGMQLLVADPY 196


>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
           dehydrogenase - Thermosinus carboxydivorans Nor1
          Length = 326

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 36/97 (37%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +A   G+ V N PG NA S  ELT  +++ L R +       K G W    +  
Sbjct: 78  DNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINLYRKINILDRETKKGNWMSWEFRP 137

Query: 467 S--ELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFD 568
           S  E+ GKT  I+G     R   R+  AFG N+I +D
Sbjct: 138 SSYEVKGKTHGIIGFGNIGREVARLSQAFGTNVIYYD 174


>UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic region:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding; n=1;
           Enterococcus faecium DO|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, catalytic region:D- isomer
           specific 2-hydroxyacid dehydrogenase, NAD-binding -
           Enterococcus faecium DO
          Length = 386

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 10/103 (9%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS---------TALKAG 439
           + I+V+ A + G  V+N PG NA +  EL    +L+ +R ++ AS           L+  
Sbjct: 61  NTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPIIEASRMVQTLTGPNILEQA 120

Query: 440 RWDRALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGF 565
              R+ Y G EL GKT+ +LGL     +VA   Y+ GM+++G+
Sbjct: 121 ENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDVLGY 163


>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
           DFL 12|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
           12
          Length = 316

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 463
           DNID+ +   +G+ V  A GAN  S  E   T  L+L R    ++  ++ G W R  L  
Sbjct: 78  DNIDMAACAARGISVHPATGANTRSVAEYVITAALMLTRRAFMSTPEMQEGAWPRGPLGE 137

Query: 464 GSELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFDP 571
           G E+AG+ L + G     +   R+     M I+G DP
Sbjct: 138 GGEIAGRKLGLYGCGAVAQAVARLAKPLSMTILGHDP 174


>UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific
           2-hydroxyacid dehydrogenase, putative; n=5;
           Eurotiomycetidae|Rep: NAD-dependant D-isomer specific
           2-hydroxyacid dehydrogenase, putative - Aspergillus
           fumigatus (Sartorya fumigata)
          Length = 335

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +  +KG+ V + P A   +  ++   LM+   R      +AL+AG+W      G
Sbjct: 88  DNIDIPACSEKGIAVSSTPVAVNHATADVGIFLMIGALRQAYIPLSALRAGQWQGKTTLG 147

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNI 556
            +  GK L ILG+ G  R +A R  AFGM I
Sbjct: 148 HDPQGKVLGILGMGGIGREMANRARAFGMKI 178


>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG08018.1 - Gibberella zeae PH-1
          Length = 901

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG-RWDRALYT 463
           D IDVD+   +G+ + N PG NA +  EL  TL    AR V        +G    +   +
Sbjct: 90  DKIDVDACASRGIKIFNTPGVNARAVAELVLTLATASARQVGSIIAKQSSGILVPKEKCS 149

Query: 464 GSELAGKTLAILGLTGRPRVATRMY--AFGMNIIGFDPF 574
           G  L  KT+ ILG+    +   +++  AF  N+I +DPF
Sbjct: 150 GLILHEKTIGILGMGNIGKCVAKIFRGAFDANVIAYDPF 188


>UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14;
           cellular organisms|Rep: Phosphoglycerate dehydrogenase -
           Rhizobium loti (Mesorhizobium loti)
          Length = 330

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY--- 460
           NID+ +A   G+ V+N PG NA +  E T   +L   R +     AL+ G W   LY   
Sbjct: 90  NIDMAAARAHGITVVNVPGRNATAVAEFTLGAILAETRLIRVGHEALRKGEWRGDLYRAD 149

Query: 461 -TGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
            TG EL+  T+ ++G      +V   + AFG +++  DP+
Sbjct: 150 RTGRELSEMTVGVIGYGNIGTKVVRLLRAFGCHVLVSDPY 189


>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD binding domain protein; n=2; cellular
           organisms|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD binding domain protein - Salinibacter
           ruber (strain DSM 13855)
          Length = 321

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 36/96 (37%), Positives = 50/96 (52%), Gaps = 5/96 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 457
           DNID+++A    V V + PG    +  +    L+L  ARHV  A   ++ G   RW+   
Sbjct: 80  DNIDLEAAEAHDVAVTHTPGVLTDATADQAWALLLAAARHVPAADRYVRDGRFERWETTH 139

Query: 458 YTGSELAGKTLAILGLTGR--PRVATRMYAFGMNII 559
             G ELA KT+ I+G+ GR    VA R   FGM +I
Sbjct: 140 LMGMELARKTIGIVGM-GRIGTAVARRALGFGMEVI 174


>UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding precursor; n=2;
           Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding precursor - Rhodopseudomonas
           palustris (strain BisB18)
          Length = 336

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 36/99 (36%), Positives = 52/99 (52%), Gaps = 2/99 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D +D+ +A K GV V+NAP AN+ S  EL    ML  +R+       +    +   L T 
Sbjct: 96  DTVDLAAAKKHGVTVLNAPLANSTSVAELALFYMLHCSRNFRLVQQTMLVDYYKAKLDTP 155

Query: 467 -SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPFR 577
            SE+A K L ++G+     RVA     F M +IGFDP++
Sbjct: 156 KSEIACKKLGLIGVGNIGSRVAKMARGFDMQVIGFDPYK 194


>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
           n=1; Blastopirellula marina DSM 3645|Rep:
           Phosphoglycerate dehydrogenase, putative -
           Blastopirellula marina DSM 3645
          Length = 320

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+++V +A ++ + V   PG    S  E T  ++L + R+V+  +  ++AG WDR    G
Sbjct: 77  DSVNVPAATEQNIAVCRTPGTLHQSVVEHTIGMILAIYRNVISQNKQVRAGDWDRT--AG 134

Query: 467 SELAGKTLAIL--GLTGRPRVATRMYAFGMNIIGFDP 571
               GKTL I+  G+ G+  VA      GM +I +DP
Sbjct: 135 PRAYGKTLGIIGYGVIGK-EVAKAAVLLGMQVIAYDP 170


>UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 380

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D + A ++G+ V+  P  + LS  E    +M+ L RH+  +   L+ G +      G
Sbjct: 114 DNVDCERARERGISVLRVPAYDPLSISEHAVAMMMSLNRHLCASRDRLRMGNFTLDGLVG 173

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
           S + GKT+ ++G    GR         F M ++G+D F
Sbjct: 174 SSMRGKTVGVVGTGKIGRGVAEILKNGFQMRVLGYDKF 211


>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
           Bacilli|Rep: Phosphoglycerate dehydrogenase -
           Lactobacillus plantarum
          Length = 324

 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRAL 457
           +NID+ +A K+ + V N P  +A++  E T  L++ LA  +V     ++      W    
Sbjct: 79  NNIDIAAAAKRQIPVTNTPNVSAVATAESTVGLIISLAHRIVEGDHLMRTSGFNGWAPLF 138

Query: 458 YTGSELAGKTLAILGLTG-RPRVATRMYAFGMNII 559
           + G  L GKTL ILGL      VA R++AF M I+
Sbjct: 139 FLGHNLQGKTLGILGLGQIGQAVAKRLHAFDMPIL 173


>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
           Thermoplasmatales|Rep: D-3-phosphoglycerate
           dehydrogenase - Picrophilus torridus
          Length = 299

 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 34/100 (34%), Positives = 52/100 (52%), Gaps = 2/100 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+IDVD A +KG+ ++ APG++  S  ELT    ++ AR ++      +    D     G
Sbjct: 76  DSIDVDYAQEKGIKIVYAPGSSTESVVELTVAFAVIAARQIIKGVENTRKN--DFTKLKG 133

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPFRV 580
            EL+GKTL I+G    GR  +A     F +  I +D + V
Sbjct: 134 IELSGKTLGIIGYGRIGR-AIANAFSVFNVRSIAYDAYPV 172



 Score = 33.5 bits (73), Expect = 4.0
 Identities = 17/57 (29%), Positives = 33/57 (57%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 242
           +LI D V     E L+           I+++ELL +I ++D ++VRS T++ ++++D
Sbjct: 5   ILICDPVDGIMIEKLSK-DFDIDNSPDITRDELLKKIGDYDIIIVRSRTKIDRDIID 60


>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase family protein; n=11; Bacteria|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase family
           protein - Coxiella burnetii
          Length = 388

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 39/107 (36%), Positives = 53/107 (49%), Gaps = 12/107 (11%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA-----------STALK 433
           +NI V      GV V+N PGANA +  EL  T +L+ +RH+ PA            T   
Sbjct: 63  NNIPVRPLTLSGVPVLNTPGANANAVKELVITGILLASRHIYPALDYARHIEGDDETITH 122

Query: 434 AGRWDRALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDP 571
               ++  ++G EL GKTL I+GL     +VA      GM  IG+DP
Sbjct: 123 QVEKNKKRFSGFELPGKTLGIIGLGQIGVKVANAAIRLGMKAIGYDP 169


>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
           specific 2-hydroxyacid dehydrogenase - Nitrosomonas
           europaea
          Length = 403

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 36/108 (33%), Positives = 58/108 (53%), Gaps = 13/108 (12%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 448
           +NI V+    +G+ V N PGANA +  EL    ML+ +R+++PA   ++    D      
Sbjct: 69  NNIPVNQMSARGIPVFNTPGANANAVRELVLAGMLMASRNLIPALRFVETLEGDDQSFNL 128

Query: 449 -----RALYTGSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
                +  ++G EL G+TL ++GL   GR +VA      GM ++G+DP
Sbjct: 129 QVEAGKKQFSGLELPGRTLGVIGLGKIGR-QVADIAIKLGMKVLGYDP 175


>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
           putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
           dehydrogenase, putative - Bacillus anthracis
          Length = 390

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 33/106 (31%), Positives = 57/106 (53%), Gaps = 10/106 (9%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 448
           +NI V+   +KG+ V N PGANA +  EL    +++ +R+++   +  K    +      
Sbjct: 62  NNIPVERCTEKGIVVFNTPGANANAVKELIIASLIMSSRNIINGVSWTKNLEGEEVPQLV 121

Query: 449 ---RALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
              +  + GSE+AGK L ++GL      VA    A GM+++G+DP+
Sbjct: 122 ESGKKQFVGSEIAGKRLGVIGLGAIGALVANDALALGMDVVGYDPY 167


>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, putative D-3- phosphoglycerate
           dehydrogenase; n=1; Propionibacterium acnes|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase, putative
           D-3- phosphoglycerate dehydrogenase - Propionibacterium
           acnes
          Length = 321

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 4/95 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 457
           +NID+D+A + GV V + PG    +  +L  TL+L + R    A   ++AG   R+D   
Sbjct: 76  NNIDLDAAKQAGVVVTSTPGVLHEATADLAFTLLLEVTRRTGEAERWVRAGRAWRYDHTF 135

Query: 458 YTGSELAGKTLAILGLTG-RPRVATRMYAFGMNII 559
             G+ L G TL I+GL      +A R  AFGMN+I
Sbjct: 136 MLGAGLQGATLGIVGLGQIGEAMARRGAAFGMNVI 170


>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
           Dehydrogenase - Geobacillus kaustophilus
          Length = 334

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 32/101 (31%), Positives = 57/101 (56%), Gaps = 5/101 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD----RA 454
           + +DVD+A +KG+ V N    +     +    L+L LAR +V  +  +K+G W+    + 
Sbjct: 80  NTVDVDAATEKGIIVANVTDYSIDEVSDHALALLLSLARKIVKLNHEVKSGTWNFNVGKP 139

Query: 455 LYTGSELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
           +Y    L G+TL ++GL   P+ +A +  AFG+ +I +DP+
Sbjct: 140 IY---RLRGRTLGLVGLGRIPQALAKKAQAFGLRVIAYDPY 177


>UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Planctomyces maris DSM 8797|Rep: D-3-phosphoglycerate
           dehydrogenase - Planctomyces maris DSM 8797
          Length = 328

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D +D+ +A  + + V   PG N  S  E    L++ +AR       A+++G W+R L   
Sbjct: 82  DAVDLAAADAQNIVVTITPGVNHHSVAEQAFALLMGIARMTRTQDRAVRSGEWEREL--T 139

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
             + G T+ I+GL GR    VATR    GM+++ +DPF
Sbjct: 140 PRVWGSTIGIVGL-GRIGQAVATRAIGMGMHVLAYDPF 176


>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
           Staphylococcus|Rep: Glycerate dehydrogenase -
           Staphylococcus epidermidis (strain ATCC 12228)
          Length = 323

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 457
           DNID+  A K GV V N P     +  EL  TLML +AR ++ A++ ++ G+W      L
Sbjct: 79  DNIDISLAKKHGVVVTNTPHVLTETTAELGFTLMLTVARRIIEATSYIQEGKWKSWGPYL 138

Query: 458 YTGSELAGKTLAILGLTGRPRV-ATRMYAFGMNII 559
            +G ++ G T+ I G+    +  A R+  F   II
Sbjct: 139 LSGKDVYGATVGIFGMGDIGKAFARRLQGFDARII 173


>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic region:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
           Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, catalytic region:D- isomer
           specific 2-hydroxyacid dehydrogenase, NAD-binding
           precursor - Chlorobium phaeobacteroides BS1
          Length = 312

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +NID+ SA K  V  +NAP  N  +  E    ++L L   ++ A   ++ G W R    G
Sbjct: 78  ENIDIQSADKHQVVCLNAPEGNRDAVAEQAVGMILTLFNRLLIADAEVRKGIWLREQNRG 137

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPFR 577
            EL GKT+ I+G   TG    A ++  F + I+ +D ++
Sbjct: 138 IELGGKTVGIIGYGNTG-SAFARKLQGFDVRILAYDKYK 175


>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic region:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding; n=1;
           Chlorobium limicola DSM 245|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, catalytic region:D- isomer
           specific 2-hydroxyacid dehydrogenase, NAD-binding -
           Chlorobium limicola DSM 245
          Length = 305

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D++D+D A +KG+ V N P     S  ELT  + L L R V  A   +K G W + +  G
Sbjct: 82  DSVDLDYAKQKGIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAHMNIKQGVWKKEI--G 139

Query: 467 SELAGKTLAILGLTGRPRVATRMY-AFGMNIIGFD 568
           + +  K + ++GL    ++A   + AFG +++ FD
Sbjct: 140 NLMYEKKVGLIGLGKIGKLAASQFQAFGCSVMAFD 174


>UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Lactobacillus salivarius subsp. salivarius UCC118|Rep:
           D-3-phosphoglycerate dehydrogenase - Lactobacillus
           salivarius subsp. salivarius (strain UCC118)
          Length = 394

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 10/106 (9%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV-VPASTALKAGRWDRALYT 463
           +NI ++ A  +G  V N PG+NA +  EL  T++L+  R V      A K    D +L T
Sbjct: 61  NNIPLEKATSQGTAVFNTPGSNANAVKELIITMLLLSVRPVFASVKWAQKLAGADVSLQT 120

Query: 464 --------GSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
                   G+EL GK + I+GL     RVA      GM +IG+DP+
Sbjct: 121 EKGKNHFAGTELYGKKIGIIGLGNIGSRVAKACMDLGMKVIGYDPY 166


>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
           protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
           phosphoglycerate dehydrogenase protein - Fulvimarina
           pelagi HTCC2506
          Length = 322

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 5/96 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD--RALY 460
           D I V +A + G+ V N P  NA S  E    L++ LAR +V     ++   W   RA  
Sbjct: 70  DFIPVQAASRLGIAVTNTPSVNAKSVAEHVFGLIICLARRIVENDAGIRRNEWHALRAAA 129

Query: 461 TGS-ELAGKTLAILGLTGRPRVATRM--YAFGMNII 559
            GS E+AGK L ++G  G  +   ++    FGMN++
Sbjct: 130 PGSCEIAGKALGLIGYGGIGQAIAQIGKLGFGMNVL 165


>UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Plesiocystis pacifica SIR-1|Rep: D-3-phosphoglycerate
           dehydrogenase - Plesiocystis pacifica SIR-1
          Length = 405

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 28/72 (38%), Positives = 39/72 (54%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D ID++ A + GV V NAP +N  S  EL    ++ L+R +   S A   GRW +     
Sbjct: 77  DQIDLEVAAQSGVAVFNAPFSNTRSVAELVIAEIVCLSRQLFERSWAAHEGRWRKDAKGA 136

Query: 467 SELAGKTLAILG 502
            E+ GKTL I+G
Sbjct: 137 HEVRGKTLGIIG 148


>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
           Eukaryota|Rep: Glycerate dehydrogenase-like protein -
           Trimastix pyriformis
          Length = 232

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 4/95 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRAL 457
           +NID+ +A ++ V V N P   A +  +LT  L+L +AR +V     ++AG    W    
Sbjct: 78  NNIDLTAANERHVVVTNTPHCLAEATADLTMGLLLAVARRLVEGDGLVRAGLFKGWAPEF 137

Query: 458 YTGSELAGKTLAILGLTG-RPRVATRMYAFGMNII 559
             G +L GKTL I+GL      VA R  AFGM I+
Sbjct: 138 LLGMDLHGKTLGIIGLGEIGTCVARRARAFGMRIV 172


>UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2;
           Filobasidiella neoformans|Rep: Phosphoglycerate
           dehydrogenase - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 316

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYT- 463
           D+ID++   +KGV ++N PG N+    ELT +L L L R V      L+AG    ++   
Sbjct: 112 DSIDIEGCKEKGVTLMNCPGENSQVVAELTLSLTLALLRRVPELDRRLRAGETMLSINNL 171

Query: 464 GSELAGKTLAILGLTGRPRVATRMY--AFGMNIIGFDP 571
           G  L GK + ++G++   R A  ++  AF   I  F P
Sbjct: 172 GRTLRGKVVGMVGISATARRAAAIFHHAFDCTIRTFSP 209


>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
           Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
           - Rhodopirellula baltica
          Length = 406

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 31/96 (32%), Positives = 52/96 (54%), Gaps = 5/96 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
           +NIDVD+A  +GV V N P     +  +L  +L+   +RHV+PA   ++ G    W+   
Sbjct: 165 NNIDVDAAKTRGVVVGNTPDVLTDATADLAVSLLFAASRHVLPAGNQVREGEWKTWEPTG 224

Query: 458 YTGSELAGKTLAILGL--TGRPRVATRMYAFGMNII 559
           + G E + KTL I+G+   G+      +  +GMN++
Sbjct: 225 WLGVEPSDKTLGIVGMGRIGKATAKRLVGGWGMNLL 260


>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
           dehydrogenases; n=1; Lawsonia intracellularis
           PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
           related dehydrogenases - Lawsonia intracellularis
           (strain PHE/MN1-00)
          Length = 302

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDV+ A +K + + N P   A++  E T  L+L L R +      +++G W + +  G
Sbjct: 81  DNIDVEYAQEKNIIIYNPPKGYAIAVAEFTVGLILSLIRQIPYQDKEVRSGVWHKRI--G 138

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDP 571
           + L GK + I+GL   G+  VA R+  FG++I   DP
Sbjct: 139 NLLHGKRVGIIGLGQVGK-AVAERLLPFGVDIAYNDP 174


>UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 387

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 11/107 (10%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD------ 448
           +NI V+   KKGV V N+PGAN+ +  EL   ++++ +R VV +   ++    D      
Sbjct: 61  NNIPVEEYAKKGVVVFNSPGANSNAVKELVLGMLVLSSRGVVQSMNWVRDNADDPEIQVD 120

Query: 449 ----RALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDPF 574
               +  + G EL GK + ++GL     +VA      GM++ G+DPF
Sbjct: 121 AEKAKKAFVGRELKGKRIGVIGLGNVGSKVANACVDLGMDVYGYDPF 167


>UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding protein; n=1; Sagittula
           stellata E-37|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding protein - Sagittula stellata
           E-37
          Length = 320

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           D +DV +   +G+ +     AN+ S  E  C L+L   +  + A  A++ G W  R    
Sbjct: 76  DAVDVAALNARGIALAVCGDANSTSVAEHACMLILAAFKRALRADVAVRRGPWGWRNQLE 135

Query: 464 GSELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
             ++ G+ L ILG  GR     AT M  FGMNI   DP+
Sbjct: 136 SQDIRGRNLLILGF-GRIGQHTATMMSGFGMNIRAHDPY 173


>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Thermosinus carboxydivorans Nor1
          Length = 365

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 5/101 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +N++V  A K+G+ V N  G NA +  + T  LML   R++  A  ++K G W +     
Sbjct: 107 ENVNVKEATKRGILVFNIEGRNAEAVSDFTVGLMLAECRNIARAHYSIKNGGWRKEFSNS 166

Query: 467 S---ELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
               EL GK + ++G    GR  VA ++  FG+  + +DPF
Sbjct: 167 DWVPELKGKKVGLVGFGYIGR-LVAQKLSGFGVTRLVYDPF 206


>UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 454

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 38/112 (33%), Positives = 56/112 (50%), Gaps = 17/112 (15%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELT-CTLMLVLA------RHVVPASTALKAGRW 445
           +NI V    + G+ V N PGANA +  EL  C+L+L         +HV       + G +
Sbjct: 93  NNIPVKEMSELGIPVFNTPGANANAVKELVVCSLLLASRGIIEGNKHVNDVINVEENGDY 152

Query: 446 ---------DRALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDP 571
                    D+A++ G+E+ GKTL ++GL     RV       GMN+IG+DP
Sbjct: 153 AKISVRIEKDKAMFGGTEIEGKTLGVIGLGAIGSRVVNAALGLGMNVIGYDP 204


>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
           putative; n=3; Filobasidiella neoformans|Rep:
           D-3-phosphoglycerate dehydrogenase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 594

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 4/100 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--Y 460
           D ID+ +A K G+ V+N PG NA +  EL   +ML LAR        ++ G     L  +
Sbjct: 110 DKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLARQTPSIDRKIRKGASVTKLDGW 169

Query: 461 TGSELAGKTLAILGLTGRPRVATRMY--AFGMNIIGFDPF 574
            G  L GKTL ++G      +  +M+  AF   I+ +DP+
Sbjct: 170 KGQMLYGKTLGVIGGGNIGLLVAKMFAGAFSGKIVLYDPY 209


>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Methanocorpusculum
           labreanum Z|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Methanocorpusculum
           labreanum (strain ATCC 43576 / DSM 4855 / Z)
          Length = 334

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 2/97 (2%)
 Frame = +2

Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 472
           +DV +A K  + V N P AN+L+  E T  L+L L + +   +   K+G W +  Y   +
Sbjct: 93  VDVPAAKKHNIAVTNVPHANSLAVSEFTVALILTLMKKIPIMNKETKSGLWHK--YISQD 150

Query: 473 LAGKTLAILGLTGRPR-VATRM-YAFGMNIIGFDPFR 577
           ++ KT+ I+G+    R VA +M Y FG  I+ +   R
Sbjct: 151 VSDKTIGIVGMGSIGRLVAKKMYYGFGCKILYYSRTR 187


>UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Rep:
           Blr3173 protein - Bradyrhizobium japonicum
          Length = 360

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-WDRALYT 463
           D +DV++    GV V+N  G NA S  E    +ML L++ ++ +   L+  R  +R    
Sbjct: 101 DPVDVEACTDAGVLVVNQSGGNAHSVAEHALAMMLTLSKRIIQSDRRLRRERDVNRNDLV 160

Query: 464 GSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
           G+E+  KT+ I+GL   GR   A      GM ++ +DP+
Sbjct: 161 GNEVEHKTVGIIGLGNVGRRIAALCNGLLGMKVLAYDPY 199


>UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n=1;
           Oenococcus oeni PSU-1|Rep: Lactate dehydrogenase related
           enzyme - Oenococcus oeni (strain BAA-331 / PSU-1)
          Length = 311

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YT 463
           DN+D   AG+ GV V   P ANA +  E T   +L L++++   S  ++ G +   L + 
Sbjct: 74  DNVDEKFAGEHGVYVTITPMANASTVAETTIAEILDLSKNLTKISDEMRQGNFAYKLDHM 133

Query: 464 GSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
           G +L+ K + ++G    GR +VA +  A GM+++ FDPF
Sbjct: 134 GFDLSHKKIGVMGYGRIGR-QVAEKANALGMDVLIFDPF 171


>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Solibacter usitatus
           Ellin6076|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Solibacter usitatus (strain
           Ellin6076)
          Length = 312

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D++D+ +A + GV V N PG  A S  E T  L+  +AR +     A + G W+R     
Sbjct: 83  DHVDLAAAARHGVTVANTPGVAARSIAEHTLALLFAVARQIPHMDAATRRGAWERG--QS 140

Query: 467 SELAGKTLAILGLTGRPRVATRM-YAFGMNII 559
            EL GKT  ++G     R   R+  A GM ++
Sbjct: 141 MELYGKTCGVIGYGAVGRHFARLATAIGMRVM 172


>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
           Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
           spumigena CCY 9414
          Length = 341

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 463
           D ID+  A K GV V+N PG +  +  E T  ++L LA+ +   +  +K G +  R    
Sbjct: 90  DAIDISVATKHGVVVVNNPGLSTTAVAEHTICMILALAKKLTFLNQCVKTGNYLIRNQVQ 149

Query: 464 GSELAGKTLAILGLTGR--PRVATR-MYAFGMNIIGFDPF 574
             +L GKTL I+GL GR    VA++   AF M ++ +DP+
Sbjct: 150 PMQLEGKTLGIVGL-GRIGSAVASKCSAAFQMRVLAYDPY 188


>UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=13; Bacteria|Rep: D-isomer
           specific 2-hydroxyacid dehydrogenase, NAD-binding -
           Shewanella sp. (strain ANA-3)
          Length = 329

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +N+D+ +A + G+ V+N P  +  S  E T  LML L R +  A    +   +      G
Sbjct: 80  NNVDLVAAKRLGMQVVNVPAYSPESVAEHTVALMLTLNRKIHKAYQRTRDANFSLEGLVG 139

Query: 467 SELAGKTLAILGLTGRPRVAT--RMYAFGMNIIGFDPF 574
             + GKT+ ++G TG+  VAT   +  FG  +I FDP+
Sbjct: 140 FNMFGKTVGVIG-TGKIGVATIKVLLGFGCKVIAFDPY 176


>UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase family protein; n=21; Pezizomycotina|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase family
           protein - Aspergillus fumigatus (Sartorya fumigata)
          Length = 343

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 37/98 (37%), Positives = 53/98 (54%), Gaps = 6/98 (6%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINA----PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL 457
           ++D+ +   +G+ V       PG N  S  + T  L+L LARHV     A+KAG+W  +L
Sbjct: 89  SLDLPALTARGIPVAGTVGRPPGVN--STVQHTWALILALARHVARDDAAVKAGKWQGSL 146

Query: 458 YTGSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGF 565
             G  L+GKTLA+LGL   G       + AFGM +I +
Sbjct: 147 --GVNLSGKTLALLGLGKLGAQVGRIAVLAFGMRVIAW 182


>UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Caldivirga
           maquilingensis IC-167|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding - Caldivirga
           maquilingensis IC-167
          Length = 326

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 3/94 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--Y 460
           D+ID+D+A ++G+ V   P     +  +L   L++ LAR V+     +++G   +    +
Sbjct: 84  DHIDLDAATRRGIPVGYTPEVLVEAVADLAIGLIITLARRVIEGDRLVRSGEAYKVWGEF 143

Query: 461 TGSELAGKTLAILGLTG-RPRVATRMYAFGMNII 559
            G+E+ GKTL ILGL      VA R  AF MN+I
Sbjct: 144 LGTEVWGKTLGILGLGNIGAAVARRAKAFNMNVI 177


>UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3;
           Gammaproteobacteria|Rep: Glycerate dehydrogenase -
           Acinetobacter sp. (strain ADP1)
          Length = 318

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 35/98 (35%), Positives = 51/98 (52%), Gaps = 7/98 (7%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 457
           +N+D+ +A  +G+ V N  G    S  + T TLML LA  ++    A+  GRW +A    
Sbjct: 78  NNVDLRAAKAQGIVVCNCQGYGTASVAQHTLTLMLALATSLLRYDHAVAQGRWQQASQFC 137

Query: 458 ---YTGSELAGKTLAILGLTGRPRVATRM-YAFGMNII 559
              Y   EL+GKTL I+G     +   R+  AFGM I+
Sbjct: 138 FLDYPIIELSGKTLGIVGYGELGKEVARLAQAFGMKIL 175


>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic region:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding; n=1;
           Clostridium phytofermentans ISDg|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, catalytic region:D- isomer
           specific 2-hydroxyacid dehydrogenase, NAD-binding -
           Clostridium phytofermentans ISDg
          Length = 316

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           DNID+  A  +G+ V   P ANA S  E T  L+L  A+++V A   L+ G ++ R    
Sbjct: 76  DNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIVIADKELRQGNYEIRNQMP 135

Query: 464 GSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGF 565
           G ++ GKTL I+G    G+          GM I+ +
Sbjct: 136 GIDVFGKTLGIIGFGRIGKSVAKKAALGLGMKILAY 171


>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
           Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
           dehydrogenase - Plesiocystis pacifica SIR-1
          Length = 327

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 5/96 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 457
           DN+DV +   + + V N PG    +  +L   L+L  AR++  AS   + GRW       
Sbjct: 85  DNVDVPACTARSIRVGNTPGVLTDATADLAMALLLSAARNLPAASLDAREGRWQTWSPTG 144

Query: 458 YTGSELAGKTLAILGLTGR--PRVATRMYAFGMNII 559
           + G EL G TL ++GL G+    VA R  AFGM+I+
Sbjct: 145 WLGLELRGATLGVVGL-GKIGLAVAQRARAFGMDIL 179


>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 743

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + ID D+  K+G+ ++N PGANA    EL  TL L +AR +   +T   +    +    G
Sbjct: 509 EKIDQDACVKRGIKILNTPGANARDVAELVVTLALSVARGIRSITTRQMSKPVPKETCNG 568

Query: 467 SELAGKTLAILGLTGRPRVATRMY--AFGMNIIGFDPF 574
             L  KT+ I+G+    R    ++   F  +I+ +D +
Sbjct: 569 LTLYQKTIGIIGMGNIGRTVAEIFRGGFAADIVAYDAY 606


>UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Ralstonia metallidurans
           CH34|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Ralstonia metallidurans (strain CH34 /
           ATCC 43123 / DSM 2839)
          Length = 317

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +NI+ D+A  +GV V +AP  N+    +    +ML  +R +      LKAG+WD      
Sbjct: 81  ENIERDAARMRGVRVCHAPDTNSQVVADHALAMMLAWSRGIAMLDRGLKAGQWDALRAPR 140

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNI 556
             + GKTL I+GL     R+A    A GM +
Sbjct: 141 PGVRGKTLGIVGLGNIGQRLAALAEAVGMRV 171


>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep:
           D-3-phosphoglycerate dehydrogenase - Desulfuromonas
           acetoxidans DSM 684
          Length = 528

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +NI +D+A  KG+ V N P  +  +  E    +M+ LAR +  A  ++  G+W    + G
Sbjct: 76  ENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQAHESMSQGKWQSTEFLG 135

Query: 467 SELAGKTLAIL--GLTGRPRVATRMYAFGMNIIGFDPF 574
           S++  KTL ++  G  GR RV        M++  +DP+
Sbjct: 136 SDINDKTLGVIGGGKIGR-RVIEYARGLHMHVNLYDPY 172



 Score = 35.5 bits (78), Expect = 0.99
 Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
 Frame = +3

Query: 72  VLIVDGVGAKCAELLN-AYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 245
           VLI D   +   +L + A GI    +  I+ + LL  I N+DAL+VR  T V++E++ A
Sbjct: 3   VLISDNFSSAGLKLFDEAEGITADYQPGITHDNLLKIINNYDALIVRGGTTVSEELIFA 61


>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
           Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
           sp. SG-1
          Length = 351

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
           DNID+ +A +K V V N P     +  +LT  LM+  AR ++ A   ++ G+   W   L
Sbjct: 106 DNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMMAAARRLIEADKYVREGKWKSWSPLL 165

Query: 458 YTGSELAGKTLAILGLTG-RPRVATRMYAFGMNII 559
             G+++  KT+ I+G+       A R   F MNI+
Sbjct: 166 MAGTDIHHKTVGIIGMGSIGEAFARRAKGFDMNIL 200


>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Syntrophobacter
           fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Syntrophobacter
           fumaroxidans (strain DSM 10017 / MPOB)
          Length = 317

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           D ID+  A ++GV V+  P AN  S  E    + ++LA+ +     AL+ G W  R    
Sbjct: 78  DAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMIRTGDIALRTGDWAARNRLI 137

Query: 464 GSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFD 568
           G+EL GK L +LG    GR         F MN+I +D
Sbjct: 138 GTELHGKALGVLGFGRIGRQTARICRNGFAMNVIYYD 174


>UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2;
           Methanosarcina|Rep: Glycerate dehydrogenase -
           Methanosarcina acetivorans
          Length = 319

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 34/93 (36%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D++ A   GV V N P     S  E    L L L R V  A   L+ G +D   Y G
Sbjct: 77  DNVDLEEATDHGVIVSNVPSYAFESVAEFVFALTLNLLRRVHLADMNLREGLFDWKYYVG 136

Query: 467 SELAGKTLAILGLTGR--PRVATRMYAFGMNII 559
           ++L  KT+ +LG TG    RV    + F MN++
Sbjct: 137 NQLMSKTIGVLG-TGEIGKRVIQIAHGFNMNVL 168


>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
           n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
           1 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 469

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + +D+D A  +G+ V N+P +N+ S  EL    ++ LAR +   S  L  G W++     
Sbjct: 134 NQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVAARC 193

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFD 568
            E+ GKTL I+G      +++    A G++++ +D
Sbjct: 194 WEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYD 228


>UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n=2;
           Lactobacillus|Rep: D-2-hydroxyisocaproate dehydrogenase
           - Lactobacillus paracasei
          Length = 333

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 28/98 (28%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYT 463
           DNID+ +  + G+ + N P  +  +  E   T  L L R++      L+AG +++A  + 
Sbjct: 80  DNIDMTAMKQYGIRLSNVPAYSPAAIAEFALTDTLYLLRNMGKVQAQLQAGDYEKAGTFI 139

Query: 464 GSELAGKTLAILGLTGRPRVATRMY-AFGMNIIGFDPF 574
           G EL  +T+ ++G     +VA +++  FG  +I +DP+
Sbjct: 140 GKELGQQTVGVMGTGHIGQVAIKLFKGFGAKVIAYDPY 177


>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
           Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
           - Burkholderia pseudomallei (Pseudomonas pseudomallei)
          Length = 424

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
 Frame = +2

Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 472
           +D+ +A   G+ V NAP +N  S  EL     ++L R V   S    AG W +      E
Sbjct: 102 VDLPAAAHHGIPVFNAPFSNTRSVAELVIAEAILLLRRVPEKSVLAHAGEWAKGAGGSFE 161

Query: 473 LAGKTLAILGLTG-RPRVATRMYAFGMNIIGFD 568
             GKT+AI+G      +V     A GM ++ +D
Sbjct: 162 ARGKTIAIVGYGNIGAQVGVLAEALGMRVVYYD 194


>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase family protein; n=3; Desulfovibrio|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase family
           protein - Desulfovibrio desulfuricans (strain G20)
          Length = 305

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+++A  +G+ V N P     +  ELT  L L L R V      L++G W + +  G
Sbjct: 81  DNVDMEAARARGIAVRNTPDGPTQAVAELTLGLALDLMRQVSRMDRELRSGVWKKRM--G 138

Query: 467 SELAGKTLAILGLTGRPRVATRMYA-FGMNIIGFDPFRVC 583
           + L GK L I+G+    R    ++   G+ +   DP   C
Sbjct: 139 NLLGGKRLGIVGMGRIGRAVADIFTPLGVQVAFNDPVSCC 178


>UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Mycobacterium gilvum
           PYR-GCK|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Mycobacterium gilvum
           PYR-GCK
          Length = 298

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D++D ++A + GV V N PG       +     +L LAR  +    A++ G W +    G
Sbjct: 74  DSVDHEAARRHGVTVRNTPGVFGYEVADSAFGYILNLARGYMAVDAAVRRGEWPKV--EG 131

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
             L G  L I+G     R +A R   FG  ++ FDPF
Sbjct: 132 ITLDGSRLGIVGFGAIGREIAKRGAGFGQEVVAFDPF 168


>UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1;
           Sagittula stellata E-37|Rep: 2-hydroxyacid dehydrogenase
           - Sagittula stellata E-37
          Length = 314

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--ALY 460
           D +DV++A + GV V N P        E+T  LML LA  V  +   ++ GRW+   A+ 
Sbjct: 79  DAVDVEAAKEHGVRVTNTPDVLNDCVAEVTLALMLALAHRVPESHAYVRDGRWETEGAMP 138

Query: 461 TGSELAGKTLAILGLTGR--PRVATRMYAFGMNII 559
             +EL G T+ I+GL GR    +A    AF M ++
Sbjct: 139 LTAELTGATVGIIGL-GRIGKAIARLAQAFSMRVV 172


>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
           protein; n=10; cellular organisms|Rep:
           D-3-phosphoglycerate dehydrogenase-like protein -
           Leishmania major
          Length = 511

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + +D+D A  +GV V N+P AN  S  EL    ++ L+R +   S  +  G W++     
Sbjct: 188 NQVDLDYATTRGVAVFNSPFANTRSVAELVIGEIISLSRKMTQRSEEVHRGVWNKTHVGC 247

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFD 568
            E+ GKT+ I+G      +V     A GMN++ +D
Sbjct: 248 YEVRGKTVGIVGYGHIGSQVGVLAEALGMNVVFYD 282



 Score = 34.7 bits (76), Expect = 1.7
 Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
 Frame = +3

Query: 75  LIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 251
           L+++GV     ELL + G I       + ++ LL +I +   L +RS TQVT+ +LDA  
Sbjct: 116 LLLEGVNPIAKELLESKGCIVEYIPNALPRDTLLEKIRDVHFLGIRSKTQVTQAILDAAP 175

Query: 252 K 254
           K
Sbjct: 176 K 176


>UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Salinibacter ruber DSM 13855|Rep: D-3-phosphoglycerate
           dehydrogenase - Salinibacter ruber (strain DSM 13855)
          Length = 512

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D +D  +   +GV V+N P +N  S  E+    M+VLAR +  A+   +   W +     
Sbjct: 159 DTVDKQACADEGVLVLNDPVSNGRSVVEMVMGEMVVLARRLYTANETGRRHLWTKDSTRR 218

Query: 467 SELAGKTLAILGLTGRPRVATRMY-AFGMNIIGFD 568
            EL  KTL+++GL    +   R+  AFGMNI  +D
Sbjct: 219 YELMDKTLSVIGLGNIGKQLARLADAFGMNIRFYD 253


>UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Clostridium
           beijerinckii NCIMB 8052|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, NAD-binding - Clostridium
           beijerinckii NCIMB 8052
          Length = 320

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YT 463
           DN+D+D+  + G+   NA G NA +  E    L+L   +++    + +K    +  L YT
Sbjct: 80  DNVDIDACTQYGIWAANAAGVNAQAVAEHVMALILSYYKNIPFLDSFIKNKIDENELQYT 139

Query: 464 GSELAGKTLAILGLTG-RPRVATRMYAFGMNII 559
           GSEL GKT+ I+G      +VA     F MNI+
Sbjct: 140 GSELKGKTIGIIGFGAVGKKVAEFCRVFDMNIL 172


>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
           Bacteroidetes|Rep: Predicted dehydrogenase -
           Flavobacteriales bacterium HTCC2170
          Length = 337

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 30/95 (31%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +NIDV  A KK + +  AP  N  +  E T  ++L L  ++  A+  ++ G+WDR    G
Sbjct: 100 ENIDVAYAKKKNIFLAAAPEGNRNAVGEHTLGMLLSLFNNLNKANLEVRNGKWDREGNRG 159

Query: 467 SELAGKTLAILGLTGRPRV-ATRMYAFGMNIIGFD 568
            EL GKT+ I+G     +  A ++  F + ++ +D
Sbjct: 160 VELDGKTVGIIGYGNMGKAFAKKLRGFDVEVLCYD 194


>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
           carboxydivorans Nor1|Rep: Glyoxylate reductase -
           Thermosinus carboxydivorans Nor1
          Length = 324

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 33/95 (34%), Positives = 51/95 (53%), Gaps = 4/95 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 460
           DN+D+ +  ++G+   N PG    +  +LT  L+L  AR +      + +GRW  +  + 
Sbjct: 80  DNVDIAACTRRGIPFGNTPGVLVEATADLTFGLLLCAARRIHEGWNQVASGRWLNNHDVP 139

Query: 461 TGSELAGKTLAILGLTGR--PRVATRMYAFGMNII 559
            G +L GKTL I+G+ GR    VA R  A GM +I
Sbjct: 140 FGIDLYGKTLGIVGM-GRIGAAVARRAKACGMKVI 173


>UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Burkholderia
           phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Burkholderia phytofirmans
           PsJN
          Length = 274

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 7/98 (7%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA---- 454
           +++D ++  K+G+G++  PG + +S  E    LML L R+++P    + AG W  +    
Sbjct: 40  NHLDTETCRKRGIGIVACPGYSTISVPEHAFALMLALRRNLMPYWHDVYAGGWSGSPTFY 99

Query: 455 --LYTGSELAGKTLAILGL-TGRPRVATRMYAFGMNII 559
             L+   +L G TL I+G   G  R+A    AFGM ++
Sbjct: 100 AELHPIQDLHGSTLGIVGAGHGGKRLAELARAFGMRVL 137


>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
           protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
           dehydrogenase related protein - Thermoplasma acidophilum
          Length = 309

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 33/99 (33%), Positives = 54/99 (54%), Gaps = 1/99 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+++  K G+ V N P A+A S  E   +++L L +        +++GRW R +   
Sbjct: 73  DNVDMNAMKKNGIMVSNIPTASADSVAEHALSMVLSLIKDQRFLDAEIRSGRWPR-ITRS 131

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPFRV 580
           S+L GKT  I+G+    R +A R+  F + II  D  R+
Sbjct: 132 SDLMGKTFGIVGMGSIGRALAARLLPFKVAIIYNDTKRM 170


>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
           Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
           Escherichia coli
          Length = 306

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 35/96 (36%), Positives = 49/96 (51%), Gaps = 1/96 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNIDVD A  K + V  A  AN++S  E+T  +ML  +R  V   +  + G+  R +  G
Sbjct: 82  DNIDVDYANSKDIVVHKALNANSISVAEMTILMMLSSSRKYVEIESQARNGKDIRLV--G 139

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDP 571
            EL  K L ++GL      VA   ++ GM I   DP
Sbjct: 140 YELYQKNLGLIGLGAIGQHVAHIAHSMGMTITAHDP 175


>UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic domain:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
           Azotobacter vinelandii AvOP|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
           specific 2-hydroxyacid dehydrogenase, NAD binding domain
           - Azotobacter vinelandii AvOP
          Length = 319

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 34/95 (35%), Positives = 48/95 (50%), Gaps = 5/95 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD----RA 454
           D ID+D A ++G+ V N+P ANA S  +L   L++   R++  A   L+AGRW       
Sbjct: 81  DGIDLDHARQRGIVVTNSPAANAASVADLAMGLLISSVRNLPAARQYLEAGRWQGNAGER 140

Query: 455 LYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNI 556
           +     L G+ L I GL      VA R  AF M +
Sbjct: 141 MPPVRGLGGRRLGICGLGAIGLNVAKRAAAFDMEV 175


>UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=4; Proteobacteria|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Polaromonas sp. (strain JS666 / ATCC
           BAA-500)
          Length = 315

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 31/93 (33%), Positives = 53/93 (56%), Gaps = 3/93 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 463
           D +DV +A ++ + V + PG       +L   LML +AR +  A   +++GRW +  +  
Sbjct: 78  DGVDVTAALERNIRVTHTPGVLNDDVADLAIGLMLSVARRIPQADQYVRSGRWPEGPMPL 137

Query: 464 GSELAGKTLAILGLTGR--PRVATRMYAFGMNI 556
             +++G+ L I+GL GR    +ATR  AFGM++
Sbjct: 138 ARKVSGERLGIVGL-GRIGQAIATRAEAFGMSV 169


>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Salinispora arenicola
           CNS205|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Salinispora arenicola
           CNS205
          Length = 345

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DNID+ +A + GV V N PG       E    L++++ R +   +     G W++ L T 
Sbjct: 77  DNIDIPAASRAGVVVANNPGLGGKPVSEHALGLLIMITRDLTAVARDAMTGAWEKRLTTR 136

Query: 467 S-ELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFDPF 574
             EL G TL I+G    G          F M ++ +DP+
Sbjct: 137 RVELTGGTLGIVGCGNVGGWMARRASAGFQMRVLAYDPY 175


>UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=185;
           Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
           Shigella flexneri
          Length = 410

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 26/72 (36%), Positives = 39/72 (54%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + +D+D+A K+G+ V NAP +N  S  EL    +L+L R V  A+     G W++     
Sbjct: 87  NQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGS 146

Query: 467 SELAGKTLAILG 502
            E  GK L I+G
Sbjct: 147 FEARGKKLGIIG 158


>UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=51;
           Bacteria|Rep: 2-hydroxyacid dehydrogenase homolog -
           Haemophilus influenzae
          Length = 331

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 28/99 (28%), Positives = 52/99 (52%), Gaps = 2/99 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +N+D+ +A + G+ V+  P  +  +  E T  LM+ L R +  A    +   +      G
Sbjct: 80  NNVDLKAAQELGIQVVRVPAYSPEAVAEHTIGLMMTLNRRIHRAYQRTREANFSLEGLIG 139

Query: 467 SELAGKTLAILGLTGRPRVATR--MYAFGMNIIGFDPFR 577
             + G+T+ ++G TG+  +A    +  FGMNI+ +DPF+
Sbjct: 140 FNMYGRTVGVIG-TGKIGIAVMRILKGFGMNILAYDPFK 177


>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
           Clostridium|Rep: 2-hydroxyacid dehydrogenase -
           Clostridium tetani
          Length = 357

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 30/95 (31%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D+I++++  K  + V N+ G +  S  ELT  L+L L R++VP +  ++ G   +  Y+ 
Sbjct: 122 DHINMETCRKNNIMVCNSAGYSTSSVVELTFGLILSLLRNIVPLNDEVRNGNTKQG-YSQ 180

Query: 467 SELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFD 568
            +LAGKTL ++G         R+  AFG N++ ++
Sbjct: 181 YDLAGKTLGVIGAGDIGTEVIRIGKAFGCNVLVYN 215


>UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1;
           Bordetella bronchiseptica|Rep: Phosphoglycerate
           dehydrogenase - Bordetella bronchiseptica (Alcaligenes
           bronchisepticus)
          Length = 329

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW----DRA 454
           D I V  A   G+ V+  P AN  S  E    LMLV AR  V A  A + G W    ++ 
Sbjct: 74  DKIAVAHADALGIPVVYTPQANVRSVAEHALMLMLVTARQAVQADAATRKGHWGFKYEQP 133

Query: 455 LYTGSELAGKTLAILGLTGRPRVATRMYAFGMNI 556
           +Y+   L GKTL ++GL    R+   M A  +N+
Sbjct: 134 MYS---LYGKTLGVIGLGRTGRLLCEMAAPALNM 164


>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
           Gluconobacter oxydans|Rep: D-3-phosphoglycerate
           dehydrogenase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 314

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
 Frame = +2

Query: 305 SAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYTGSELAG 481
           +A  +GV V NAP  N+ S  E+T  L+L + R +  A  A++ G W+ R    G EL  
Sbjct: 81  AAAARGVLVTNAPNTNSRSVAEMTIGLLLAVVRRLCEADLAVREGNWEFRYTGKGMELHT 140

Query: 482 KTLAILGLTGRPRVATRM--YAFGMNIIGFDP 571
           +TL ++G     R   ++     GM ++ + P
Sbjct: 141 RTLGLVGFGAIARHVAQIAGQGLGMRVMAWSP 172


>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
           555|Rep: SerA - Clostridium kluyveri DSM 555
          Length = 320

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +N+D+ +A +  + + NAP +N  +  E T  L++ LA+        L+ G +      G
Sbjct: 76  NNVDIKTASELSIQITNAPESNKNTVAEYTMGLIIALAKKFFLYDRGLRKGNFKVRDILG 135

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNIIGF 565
            +L GK L I+GL   G+         FGM +IGF
Sbjct: 136 IDLEGKVLGIVGLGSIGKLLALKASKGFGMKVIGF 170


>UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
           Bacteroidetes|Rep: D-3-phosphoglycerate dehydrogenase -
           Flavobacteriales bacterium HTCC2170
          Length = 329

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 40/104 (38%), Positives = 52/104 (50%), Gaps = 8/104 (7%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLM------LVLARHVVPASTALKAGRWD 448
           DNIDV  A +KG+ VIN P A++ S  EL    +      L  A   +P     K  +  
Sbjct: 89  DNIDVAYAKEKGLHVINTPAASSESVAELVFAHLFGGVRFLYDANRNMPLEGDSKFKQLK 148

Query: 449 RALYTGSELAGKTLAILGLTGRPRVATRMYA--FGMNIIGFDPF 574
           ++   GSEL GKTL ++G  GR   AT   A   GM +I  DPF
Sbjct: 149 KSYAGGSELRGKTLGVIGF-GRIGQATAKIALGIGMKVIYSDPF 191



 Score = 34.3 bits (75), Expect = 2.3
 Identities = 26/65 (40%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
 Frame = +3

Query: 57  VDIKSVLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDA-LVVRSATQVT 227
           V+   +L  DG+       L A G  I+TTT A+   +E + E  N  A L+VRSATQV 
Sbjct: 11  VNSMKILANDGISQTGINELEAAGFEISTTTVAQEQLKEFINE--NQIAGLLVRSATQVR 68

Query: 228 KEVLD 242
           K+++D
Sbjct: 69  KDIID 73


>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Mycobacterium sp. (strain KMS)
          Length = 321

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 38/97 (39%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
           DNIDV +A   GV V N PG    +  + T  L+L + R VV     L++ R   W   +
Sbjct: 83  DNIDVAAAHAAGVTVTNTPGVLDNATADHTFALILAVTRRVVDGDRFLRSRRPWIWGPRM 142

Query: 458 YTGSEL-AGKTLAILGL--TGRPRVATRMYAFGMNII 559
            TG ++ AG TL ILG    GR  VA R  AF M ++
Sbjct: 143 LTGLDVSAGATLGILGYGRIGR-AVARRARAFDMTVL 178


>UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6;
           Bacteria|Rep: Phosphoglycerate dehydrogenase -
           Gloeobacter violaceus
          Length = 310

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D  +A   G+ + N P        ++  + +  LAR        ++AG W +    G
Sbjct: 83  DNVDFAAARALGIPIANTPAMFGAEVADVAVSYVTALARETFSVDREVRAGGWPKP--CG 140

Query: 467 SELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDP 571
             LAGKT+A++G     +  A R+ A  M +I +DP
Sbjct: 141 VSLAGKTVALVGFGDIGKATARRLVAAEMRVIAYDP 176


>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase
           NAD-binding - Xanthobacter sp. (strain Py2)
          Length = 359

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D +DVD+A   G  V  A GAN  +  + T  LML + R +  +  A+  G W R L  G
Sbjct: 116 DRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLAVLRRLKASQAAIARGDW-RVL-VG 173

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNII 559
           ++L GKT+ ++G    GR +VA R+  F + ++
Sbjct: 174 ADLTGKTVGLIGFGRIGR-QVARRLSGFDVTVL 205


>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
           Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
           Oceanicaulis alexandrii HTCC2633
          Length = 407

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + +D+ +A ++GV V NAP AN  S  ELT   +++L R +     A++ G W +     
Sbjct: 83  NQVDLVAAAERGVPVFNAPFANTRSVAELTMASVIMLMRRIPEKMFAIQRGEWLKTADGA 142

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFD 568
           +E+  K L I+G      +++    A GM++  +D
Sbjct: 143 NEVRKKKLGIIGYGNIGAQLSVIASALGMHVYYYD 177


>UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15;
           Pseudomonadales|Rep: 2-keto-D-gluconate reductase -
           Acinetobacter sp. (strain ADP1)
          Length = 321

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---AL 457
           DN DV    +K + + + P     +  +L  TL++  AR V       KAG W R   A 
Sbjct: 78  DNYDVQYLNQKKIWLAHTPHVLTETTADLAFTLLVSAARKVPQLDAWTKAGEWKRTVGAA 137

Query: 458 YTGSELAGKTLAILGL--TGRPRVATRMYAFGMNII 559
             G ++ GKTL I+GL   G       +Y F MNI+
Sbjct: 138 QFGQDIFGKTLGIIGLGNIGAAIARRGLYGFNMNIL 173


>UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate
           dehydrogenase; n=1; Desulfotalea psychrophila|Rep:
           Related to D-3-phosphoglycerate dehydrogenase -
           Desulfotalea psychrophila
          Length = 393

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 36/108 (33%), Positives = 57/108 (52%), Gaps = 13/108 (12%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV------VPASTALKAGRWD 448
           +N++V+ A KKG+ V N PGANA +  +L   ++ V  R++        + TA+   + D
Sbjct: 62  NNVNVERATKKGICVFNTPGANANAVVDLVFPMLGVWKRNIFNGINFCKSLTAVDPDKVD 121

Query: 449 ------RALYTGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDP 571
                 ++ Y G E+AGK L ++GL     R+A       MN+ GFDP
Sbjct: 122 SVVEAQKSAYKGEEIAGKNLTVVGLGQIGVRLANGGIQRLMNVKGFDP 169


>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
           Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
           dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
           / Gra Bd 1)
          Length = 321

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+D+D      + ++  P   A +  EL   +ML L+R ++ A   L+ G W +    G
Sbjct: 74  DNVDLDYLRNHDLKLVRIPQPGARAVAELAFGMMLALSRQILVADQLLRKGTWAKHQLRG 133

Query: 467 SELAGKTLAILGLTGRPRVATRM-YAFGMNIIG 562
             L  K L I+GL     +  +M  A+GM ++G
Sbjct: 134 HLLVNKQLGIVGLGNIGTLLGQMGLAWGMQVLG 166


>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
           Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
           - Streptococcus agalactiae 515
          Length = 318

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 33/103 (32%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 457
           D++D   A +KG+ V N+P A  +   E+T  L+L  ++ +    + +++G W       
Sbjct: 78  DHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASKRLAFYDSIVRSGEWIDPSEQR 137

Query: 458 YTGSELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPFRV 580
           Y G  L G TL I G+ GR    VA    AFGM ++  D +R+
Sbjct: 138 YQGLTLQGSTLGIYGM-GRIGLTVANFAKAFGMTVVYNDVYRL 179


>UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Polaromonas sp.
           JS666|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 309

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 32/90 (35%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 463
           D I V  A  +G+ V + PG    + CEL   L+L L R +  +   ++ GRW D A   
Sbjct: 73  DGIPVAYAQARGIAVTHTPGVLDDAVCELGVGLLLGLLRDIPASDRFVRDGRWSDSAYPL 132

Query: 464 GSELAGKTLAILGLTGRPR-VATRMYAFGM 550
            + LAGK + I+GL    R +A R+  FG+
Sbjct: 133 TTSLAGKAVGIVGLGRIGRGIAARLQPFGV 162


>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase
           NAD-binding - Anaeromyxobacter sp. Fw109-5
          Length = 313

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 457
           +++D+D+  ++GV V N PG    +  +    L+L  AR VV     ++AG W   D A 
Sbjct: 78  NHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEGDRVVRAGGWTEVDPAW 137

Query: 458 YTGSELAGKTLAILG 502
             G+E+ GKT+ ++G
Sbjct: 138 MLGTEVTGKTVGVVG 152


>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
           Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
           - Microscilla marina ATCC 23134
          Length = 316

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D ID+ +A  +G+ V+NAP  N  +  E T  ++L L  +V  A   +K   W R    G
Sbjct: 77  DKIDLSAANARGIKVLNAPEGNRDAVGEQTIGMLLSLLHNVQRADWEVKNFAWKREANRG 136

Query: 467 SELAGKTLAILGLTGRPRV-ATRMYAFG-MNIIGFD 568
            EL  K + ++G     +  A R+ +FG  ++I +D
Sbjct: 137 VELMDKVVGVIGYGNMGKAFAKRLSSFGCKDVIAYD 172


>UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 387

 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 11/107 (10%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS----------TALKA 436
           +NI +D    KGV V N PGANA    EL    ML+ +R ++  +             K 
Sbjct: 61  NNIPLDKCADKGVVVFNTPGANANGVKELVLCGMLLASRDIIGGNKWVANNTDNENISKD 120

Query: 437 GRWDRALYTGSELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDPF 574
               +  + G+E+ GK L ++GL    R VA    + GM + G DPF
Sbjct: 121 MEKAKKNFAGNEIKGKKLGVIGLGAIGRLVANAAESMGMEVYGNDPF 167


>UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp.
           SK209-2-6|Rep: Dehydrogenase - Roseobacter sp. SK209-2-6
          Length = 343

 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 3/99 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 463
           D +DV++A  KG+ V N          +    L L LAR +     A  AG W  ++   
Sbjct: 90  DIVDVNAATAKGILVTNVQNYCTEEVADHAIALWLALARKLPDYDRATHAGLWQWQSGQP 149

Query: 464 GSELAGKTLAI--LGLTGRPRVATRMYAFGMNIIGFDPF 574
              L G+T+ +  LG  G+  +A R  AFG+N+I +DPF
Sbjct: 150 VHRLRGRTMGVVSLGKIGQ-AIAARARAFGVNVIAYDPF 187


>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
           KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Comamonas testosteroni KF-1
          Length = 320

 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D++D+++A  +GV V  A  ANA +  E    LML L R +      ++AG W  + + G
Sbjct: 86  DSVDMEAARTQGVAVAVAQAANAPAVAEHALALMLALVRQLPQLDQQVRAGGWAGSNWQG 145

Query: 467 SELAGKTLAILGLTGRPRVATRM-YAFGMNIIGFDP 571
            +  G T+ I+G     R   ++  A G  ++   P
Sbjct: 146 RDFRGSTVGIVGYGAIGRATAQLAAALGAKVLVLRP 181


>UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase NAD-binding; n=24; Rhodobacterales|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase
           NAD-binding - Silicibacter sp. (strain TM1040)
          Length = 322

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
           ++ID ++A   GV V N PGA   +  ++  TLML+ AR        +++G+W       
Sbjct: 85  NHIDAEAARAAGVEVTNTPGAVTDATADIALTLMLMTARRAGEGERLVRSGQWQGWHPTQ 144

Query: 458 YTGSELAGKTLAILGLTGR--PRVATRM-YAFGMNI 556
             G  L+GK L ++GL GR    +A R  + FGM I
Sbjct: 145 MLGLHLSGKRLGVVGL-GRIGDAIARRAHFGFGMEI 179


>UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;
           Trichocomaceae|Rep: Contig An11c0250, complete genome -
           Aspergillus niger
          Length = 336

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D ID ++  K+G+ V NAP     +  +L   L+L   R++ PA  +L AG + + +  G
Sbjct: 91  DPIDTEACAKRGIIVTNAPDPVTDATADLAVLLLLGALRNLNPAIRSLYAGTFKQGVGFG 150

Query: 467 SELAGKTLAILGL--TGRPRVATRMYAFGMNII 559
            +  GKTL ILG+   GR  V  R   FG+  +
Sbjct: 151 HDPQGKTLGILGMGRIGR-AVKQRCEPFGIKTV 182


>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
           acidophilus|Rep: Glyoxylate reductase - Lactobacillus
           acidophilus
          Length = 321

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 36/96 (37%), Positives = 50/96 (52%), Gaps = 5/96 (5%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRAL 457
           D+ID+D A +KG+ V N P +      EL  T+++  AR +     AL+ G +   D   
Sbjct: 81  DHIDIDYAREKGIVVTNCPNSVLRPTAELALTMIMASARRIRYYDHALREGVFLNVDEYD 140

Query: 458 YTGSELAGKTLAILGLTGR--PRVATRMYAFGMNII 559
             G  + GKTL ILG+ GR   +VA    A GM II
Sbjct: 141 SQGYTIEGKTLGILGM-GRIGQQVARFAKALGMKII 175


>UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1;
           Lactobacillus brevis ATCC 367|Rep: 2-hydroxyacid
           dehydrogenase - Lactobacillus brevis (strain ATCC 367 /
           JCM 1170)
          Length = 330

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 34/98 (34%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPG-ANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALY 460
           +N+DV +A   G  V   P      S  E     +L + R  VPA+   +AGR+ DRA +
Sbjct: 85  NNVDVKAAKAHGTLVTIVPQLVERDSVAENELVNLLTMVRRTVPAAERERAGRYEDRAEF 144

Query: 461 TGSELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFDP 571
            G+EL+GKT  ++G      RVA     FG  +   DP
Sbjct: 145 MGNELSGKTFGVIGCGNIGSRVAELFSVFGGQVFIADP 182


>UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1;
           Bacillus sp. B14905|Rep: D-3 phosphoglycerate
           dehydrogenase - Bacillus sp. B14905
          Length = 319

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           D++ +  A  + V V NA G    +  ELT  L+L + RH+      + A  +  A + G
Sbjct: 82  DHVGIGQARNQDVMVCNAAGYANQAVAELTIGLVLDVYRHITQGDKEIHADHFPGA-FQG 140

Query: 467 SELAGKTLAILGLTGRPRVAT-RMY-AFGMNIIGFDPFR 577
           SE+ GKT+ ++G TG+  + T R++ AFG  I+  D  R
Sbjct: 141 SEIKGKTVGLIG-TGKIGMMTARLFKAFGAKIVASDQSR 178


>UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding precursor; n=2;
           Actinomycetales|Rep: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding precursor - Nocardioides sp.
           (strain BAA-499 / JS614)
          Length = 318

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 4/99 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           DN+DV +A + G+ V N P     +  +     +L LAR +   S  ++  RW R    G
Sbjct: 79  DNVDVPAARELGIHVANVPDYGVETVADHASASLLALARRLPIYSGRIRTERWVRPGDIG 138

Query: 467 SELAGKTLAILGLTGRPRVA----TRMYAFGMNIIGFDP 571
           + + G   +++GL G  R+A     R+  FG + + +DP
Sbjct: 139 A-IRGMRSSVVGLVGMGRIAQAVHDRLRPFGFSFVAYDP 176


>UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2;
           Actinomycetales|Rep: Glyoxylate reductase - Arthrobacter
           aurescens (strain TC1)
          Length = 329

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRAL 457
           +NIDVD+A + G+ V N PG    +  ++   L+L  AR VV +   ++ G+   W+   
Sbjct: 78  NNIDVDAATRHGILVGNTPGVLTDATADVAMLLILGTARRVVESDRVVRDGKFLGWEPEF 137

Query: 458 YTGSELAGKTLAILGLTGRPR-VATRMYAFGMNIIGFDP 571
             G +++G  L + G     R VA R   FGM  + F P
Sbjct: 138 MLGRDVSGAVLGLAGFGRIARAVARRALGFGMEEL-FSP 175


>UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=3; Bacteria|Rep: D-isomer
           specific 2-hydroxyacid dehydrogenase, NAD-binding -
           Pelobacter propionicus (strain DSM 2379)
          Length = 318

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 35/97 (36%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
           +NID+ +A  +G+GV N P  +  +  +L  T ML L+  +V   T L+ G  D   ++L
Sbjct: 80  NNIDIAAARSRGIGVCNVPSYSTDAVAQLAITFMLNLSASLVQQQTMLRRGNLDNFQKSL 139

Query: 458 YTGS-ELAGKTLAILGL--TGRPRVATRMYAFGMNII 559
                EL GKTL ++G    GR RV       GM II
Sbjct: 140 QLPHFELNGKTLGVIGFGEIGR-RVIAIARTLGMKII 175


>UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase family protein; n=16; Proteobacteria|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase family
           protein - Silicibacter pomeroyi
          Length = 330

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 5/95 (5%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD--RALY- 460
           +ID D+    G+ V N P   +    ++  TLML++AR        L+AG+W   R  + 
Sbjct: 89  HIDSDAVRAHGITVSNTPDVLSECTADIAMTLMLMVARRAGEGERELRAGQWTGWRPTHL 148

Query: 461 TGSELAGKTLAILGL--TGRPRVATRMYAFGMNII 559
            GS+++GK L I+G    G+       + FGM I+
Sbjct: 149 VGSKVSGKVLGIVGFGRIGQAMAQRAHHGFGMKIL 183


>UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family
           dehydrogenase; n=1; Sodalis glossinidius str.
           'morsitans'|Rep: Putative 2-hydroxyacid-family
           dehydrogenase - Sodalis glossinidius (strain morsitans)
          Length = 211

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 35/94 (37%), Positives = 53/94 (56%), Gaps = 3/94 (3%)
 Frame = +2

Query: 293 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK-AGRWDRALYTGS 469
           ID+D+A    + ++    ++A    ELT  L+L LARH+VP + AL+ +  W + L  G 
Sbjct: 86  IDLDAARAHNI-IVCGTASDAAPPMELTWALILGLARHLVPENQALRHSDPWQQIL--GM 142

Query: 470 ELAGKTLAILGL--TGRPRVATRMYAFGMNIIGF 565
            L GK L +LGL   G   V+    AFGM++I +
Sbjct: 143 TLKGKLLCLLGLGKIGGAMVSVTQ-AFGMDVIAW 175


>UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellular
           organisms|Rep: D-lactate dehydrogenase - Escherichia
           coli (strain K12)
          Length = 329

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           +N+D+D+A + G+ V+  P  +  +  E    +M+ L R +  A    +   +     TG
Sbjct: 80  NNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTG 139

Query: 467 SELAGKTLAILGLTGRPRVATR--MYAFGMNIIGFDPF 574
             + GKT  ++G TG+  VA    +  FGM ++ FDP+
Sbjct: 140 FTMYGKTAGVIG-TGKIGVAMLRILKGFGMRLLAFDPY 176


>UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; n=1;
            Gibberella zeae PH-1|Rep: hypothetical protein FG00146.1
            - Gibberella zeae PH-1
          Length = 1068

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
 Frame = +2

Query: 287  DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV--VPASTALKAGRWDRALY 460
            D IDV++  +  V V N PG NA +  E+T  L L +AR V  V     ++     +   
Sbjct: 824  DKIDVEACKRHNVKVCNTPGVNASAVAEMTLCLALTVAREVPDVVIRQKIQGEAIRKETV 883

Query: 461  TGSELAGKTLAILGLTGRPRVATRMYAFGM--NIIGFDPF 574
             G  L+ K + ++G+    +   +M+  G+   II FDP+
Sbjct: 884  AGMLLSRKIIGVVGMGHIGQAIAQMFVGGLQAEIIAFDPY 923


>UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Rep:
            Ribeye a protein - Danio rerio (Zebrafish) (Brachydanio
            rerio)
          Length = 1147

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 34/105 (32%), Positives = 54/105 (51%), Gaps = 9/105 (8%)
 Frame = +2

Query: 287  DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR------HVVPASTALKAGRWD 448
            DNID+ +AG+ G+ V N P A      + T   +L L R        +   T +++    
Sbjct: 852  DNIDIKAAGEMGIAVCNIPSAAVEETADSTLCHILNLYRRNTWLYQAMREGTRVQSVEQI 911

Query: 449  RALYTG-SELAGKTLAILGLTGR--PRVATRMYAFGMNIIGFDPF 574
            R + +G + + G+TL ++G  GR    VA R  AFG N+I +DP+
Sbjct: 912  REVASGAARIRGETLGLIGF-GRSGQAVAVRAKAFGFNVIFYDPY 955


>UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putative -
           Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 317

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALY 460
           D +D+  A ++ + V   PG  A    +L   LML + R V      ++ GRW     L 
Sbjct: 82  DKVDLARARRRNIDVTTTPGVLADDVADLGIALMLAVLRRVGDGDRLVREGRWAAGEQLP 141

Query: 461 TGSELAGKTLAILGL--TGRPRVATRMYAFGMNI 556
            G    GK + +LGL   GR  +A+R  AFGM++
Sbjct: 142 LGHSPKGKRIGVLGLGQIGR-ALASRAEAFGMSV 174


>UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72;
           Alphaproteobacteria|Rep: Gluconate 2-dehydrogenase -
           Brucella melitensis
          Length = 360

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 7/97 (7%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL--KAGR---WDR 451
           DNIDV +A ++G+ V N P        ++T  L+L + R +V  +  +  + G+   W  
Sbjct: 110 DNIDVAAAARRGITVTNTPNVLTEDTADMTLALLLSVPRRLVEGANVINERHGQWPGWSP 169

Query: 452 ALYTGSELAGKTLAILGLTGR--PRVATRMYAFGMNI 556
               G  + GK L I+G+ GR    VA R  AFG++I
Sbjct: 170 TWMLGRRIWGKRLGIVGM-GRIGTAVARRAKAFGLSI 205


>UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-terminal
           domain; n=1; Symbiobacterium thermophilum|Rep:
           Phosphoglycerate dehydrogenase, N-terminal domain -
           Symbiobacterium thermophilum
          Length = 140

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 23/53 (43%), Positives = 33/53 (62%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 445
           DNIDV +A ++G+ V+N P ANA+S  E     +  LA+ VV    A++ GRW
Sbjct: 77  DNIDVAAATERGILVLNTPEANAVSVAEHAIAAIAALAKRVVFMDRAVRDGRW 129


>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
           specific; n=1; Syntrophus aciditrophicus SB|Rep:
           2-hydroxyacid dehydrogenase, D-isomer specific -
           Syntrophus aciditrophicus (strain SB)
          Length = 326

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RAL 457
           +++ + S   +G+ ++N  G    +  +L  TL+L L R V      +++G W      L
Sbjct: 93  NHLPITSCQSRGIRIVNTQGVLTDATADLALTLLLSLTRRVREGEALVRSGHWKGWAPDL 152

Query: 458 YTGSELAGKTLAILGLTGRPRV-ATRMYAFGMNII 559
             G+ L GKT  ILG     R  A R++A GM +I
Sbjct: 153 LLGTGLTGKTCGILGSGPIGRAFARRVWAIGMKVI 187


>UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, catalytic domain:D- isomer specific
           2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
           Azotobacter vinelandii AvOP|Rep: D-isomer specific
           2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
           specific 2-hydroxyacid dehydrogenase, NAD binding domain
           - Azotobacter vinelandii AvOP
          Length = 388

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
 Frame = +2

Query: 290 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 469
           ++D+D+  ++GV V    G+  ++  EL  TL+L   R ++PA  A + GRW   +  G 
Sbjct: 147 HLDLDACTRRGVAVAEGRGS-PIAPAELAWTLILNARRRLLPAIAAFREGRWQTNI--GE 203

Query: 470 ELAGKTLAILGLTGR--PRVATRMYAFGMNII 559
            LAG TL I G  G+   R+A    AF M ++
Sbjct: 204 RLAGLTLGIWGY-GKIGQRLARYAQAFEMPVL 234


>UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1;
           Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
           glyoxylate reductase - Rhizobium leguminosarum bv.
           viciae (strain 3841)
          Length = 312

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY-T 463
           D ID+    K+GV V     A      +L  TL ++L R +V A    + G W+R  +  
Sbjct: 79  DKIDIPGLEKRGVRVRCVGEALTDDVADLAMTLTIMLCRDLVRADAFARGGEWERGRFDV 138

Query: 464 GSELAGKTLAILGLTGR--PRVATRMYAFGMNIIG 562
           G    G T+ I GL+GR    +A R  A  M I G
Sbjct: 139 GDSPVGMTIGIGGLSGRIGQAIAARASASKMKIAG 173


>UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid
           dehydrogenase, NAD-binding; n=5; Burkholderia|Rep:
           D-isomer specific 2-hydroxyacid dehydrogenase,
           NAD-binding - Burkholderia cepacia (strain ATCC 53795 /
           AMMD)
          Length = 320

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 35/100 (35%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL--- 457
           D++DV +A ++G+ V NAP A      + T  LML   R        ++AG W ++    
Sbjct: 84  DHLDVAAARERGIVVSNAPDALTDCTADFTMLLMLAACRRASEYERIVRAG-WGKSFGMT 142

Query: 458 -YTGSELAGKTLAILGL--TGRPRVATRMYAFGMNIIGFD 568
              G+ + GKTL I+G    GR  VA R   FGM I+  D
Sbjct: 143 DMLGTRVNGKTLGIVGFGRIGR-AVAQRARGFGMKIVYTD 181


>UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
           Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
           - Propionibacterium acnes
          Length = 417

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
 Frame = +2

Query: 287 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 466
           + +D+D+  + GV   NAP +N  S  EL    ++ LAR +   +T +  G W ++    
Sbjct: 98  NQMDLDALAEAGVPAFNAPYSNTRSVVELVMAEIIALARRLGDRNTQMHNGVWRKSAIGS 157

Query: 467 SELAGKTLAILGLTG-RPRVATRMYAFGMNIIGFD 568
            E+ G+ L I+G      +++    A GM +  +D
Sbjct: 158 HEIRGRRLGIIGYGNIGQQLSVVAEAMGMQVFFYD 192


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 621,755,530
Number of Sequences: 1657284
Number of extensions: 12825498
Number of successful extensions: 65109
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 56317
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 64441
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 43562448615
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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