Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fe100P01_F_C02
(650 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7Q0A0 Cluster: ENSANGP00000020090; n=3; Endopterygota|... 193 4e-48
UniRef50_Q17DN9 Cluster: Enhancer of split protein, putative; n=... 190 2e-47
UniRef50_Q01070 Cluster: Enhancer of split mgamma protein (E(spl... 142 7e-33
UniRef50_Q01069 Cluster: Enhancer of split mbeta protein (E(spl)... 140 3e-32
UniRef50_Q01071 Cluster: Enhancer of split mdelta protein (E(spl... 118 1e-25
UniRef50_Q01068 Cluster: Enhancer of split m3 protein (E(spl)m3)... 103 4e-21
UniRef50_Q9N6W7 Cluster: HLHmdelta protein; n=1; Drosophila hyde... 100 3e-20
UniRef50_P13098 Cluster: Enhancer of split m8 protein (E(spl)m8)... 86 6e-16
UniRef50_UPI00003BFC0E Cluster: PREDICTED: similar to deadpan CG... 85 1e-15
UniRef50_Q26263 Cluster: Protein deadpan; n=3; Protostomia|Rep: ... 82 1e-14
UniRef50_Q14469 Cluster: Transcription factor HES-1; n=52; Eutel... 79 7e-14
UniRef50_UPI00003C06C0 Cluster: PREDICTED: similar to Protein ha... 79 9e-14
UniRef50_Q90468 Cluster: HER-6 protein; n=4; Clupeocephala|Rep: ... 79 9e-14
UniRef50_Q9NFW8 Cluster: DNA-binding-protein hairy; n=2; Enteleg... 78 2e-13
UniRef50_UPI00015B599D Cluster: PREDICTED: similar to hairy prot... 77 4e-13
UniRef50_Q6V6Z0 Cluster: Hairy G protein; n=1; Branchiostoma flo... 77 5e-13
UniRef50_Q4H3N9 Cluster: Transcription factor protein; n=3; Eume... 77 5e-13
UniRef50_Q8T306 Cluster: Helix-loop-helix transcription factor; ... 76 6e-13
UniRef50_Q16NK4 Cluster: Hairy protein; n=4; Diptera|Rep: Hairy ... 76 8e-13
UniRef50_UPI0001554A1E Cluster: PREDICTED: hypothetical protein;... 75 1e-12
UniRef50_Q56KF1 Cluster: Enhancer of split m5 protein; n=2; Dros... 75 1e-12
UniRef50_A7RU73 Cluster: Predicted protein; n=1; Nematostella ve... 74 3e-12
UniRef50_Q208Q9 Cluster: AmphiHairyA; n=6; Branchiostoma florida... 73 5e-12
UniRef50_A2TIR6 Cluster: Splhairy; n=1; Panulirus argus|Rep: Spl... 73 5e-12
UniRef50_Q6V6Z2 Cluster: Hairy E protein; n=3; Branchiostoma flo... 72 1e-11
UniRef50_Q29G34 Cluster: GA19235-PA; n=1; Drosophila pseudoobscu... 71 2e-11
UniRef50_P29303 Cluster: Protein hairy; n=2; Muscomorpha|Rep: Pr... 71 2e-11
UniRef50_Q17DP5 Cluster: Hairy protein; n=2; Culicidae|Rep: Hair... 70 4e-11
UniRef50_P14003 Cluster: Protein hairy; n=3; Sophophora|Rep: Pro... 69 7e-11
UniRef50_A7RYX4 Cluster: Predicted protein; n=2; Nematostella ve... 69 1e-10
UniRef50_Q9Y543 Cluster: Transcription factor HES-2; n=14; Theri... 69 1e-10
UniRef50_Q9DEU7 Cluster: Transcription factor Her-8b; n=3; Danio... 67 3e-10
UniRef50_UPI0000D57461 Cluster: PREDICTED: similar to CG8704-PA;... 66 7e-10
UniRef50_Q1ECY5 Cluster: LOC565269 protein; n=3; Danio rerio|Rep... 64 3e-09
UniRef50_Q0VFM2 Cluster: Hairy and enhancer of split 6 gene 2; n... 64 3e-09
UniRef50_Q9VWX7 Cluster: CG5927-PA; n=1; Drosophila melanogaster... 64 4e-09
UniRef50_Q6JJ70 Cluster: Hairy/enhancer of split; n=1; Strongylo... 63 6e-09
UniRef50_Q7KM13 Cluster: Hairy/enhancer-of-split related with YR... 62 1e-08
UniRef50_UPI000065D5D5 Cluster: Transcription factor HES-3 (Hair... 61 2e-08
UniRef50_Q4H3P0 Cluster: Transcription factor protein; n=1; Cion... 60 3e-08
UniRef50_Q568C3 Cluster: Her3 protein; n=3; Danio rerio|Rep: Her... 59 1e-07
UniRef50_Q17LB7 Cluster: Transcription factor Hairy, putative; n... 58 2e-07
UniRef50_Q8T8A9 Cluster: Hairy E(SPL) like bHLH transcription fa... 57 4e-07
UniRef50_Q4H3E4 Cluster: Transcription factor protein; n=1; Cion... 57 4e-07
UniRef50_UPI000058443F Cluster: PREDICTED: similar to hairy E pr... 56 6e-07
UniRef50_A1L3K9 Cluster: LOC100037036 protein; n=2; Xenopus|Rep:... 56 7e-07
UniRef50_Q6P0J1 Cluster: Hairy and enhancer of split 6; n=3; Dan... 55 2e-06
UniRef50_Q5XHC4 Cluster: LOC495039 protein; n=7; Tetrapoda|Rep: ... 54 2e-06
UniRef50_Q5S4J7 Cluster: Enhancer of split complex m5 protein; n... 54 2e-06
UniRef50_Q4H3P1 Cluster: Transcription factor protein; n=1; Cion... 54 2e-06
UniRef50_UPI0000D563AB Cluster: PREDICTED: similar to CG10446-PA... 54 3e-06
UniRef50_UPI0000E48019 Cluster: PREDICTED: similar to hairy/enha... 53 5e-06
UniRef50_Q0P454 Cluster: Zgc:153398; n=6; Clupeocephala|Rep: Zgc... 53 5e-06
UniRef50_A7RYX3 Cluster: Predicted protein; n=1; Nematostella ve... 53 5e-06
UniRef50_UPI00015B46B7 Cluster: PREDICTED: similar to GA10322-PA... 53 7e-06
UniRef50_UPI0000F1EAFE Cluster: PREDICTED: hypothetical protein;... 53 7e-06
UniRef50_Q6YID3 Cluster: Hairy and enhancer of split; n=1; Helob... 52 9e-06
UniRef50_A3KQ57 Cluster: Hairy and enhancer of split related-7; ... 52 1e-05
UniRef50_Q9VJ16 Cluster: CG10446-PA; n=4; Diptera|Rep: CG10446-P... 52 2e-05
UniRef50_A7RYX2 Cluster: Predicted protein; n=1; Nematostella ve... 52 2e-05
UniRef50_Q4RKD6 Cluster: Chromosome 21 SCAF15029, whole genome s... 51 2e-05
UniRef50_Q7Q509 Cluster: ENSANGP00000020858; n=1; Anopheles gamb... 51 3e-05
UniRef50_Q96HZ4 Cluster: Transcription cofactor HES-6; n=18; cel... 51 3e-05
UniRef50_Q9YI65 Cluster: Basic-helix-loop-helix transcription fa... 50 4e-05
UniRef50_UPI00000181D8 Cluster: Homolog of Brachydanio rerio "Ha... 50 6e-05
UniRef50_Q8UW74 Cluster: HES-related 1A; n=4; Xenopus|Rep: HES-r... 50 6e-05
UniRef50_Q7T3J0 Cluster: Hairy and enhancer of split 5; n=3; Dan... 50 6e-05
UniRef50_A7S152 Cluster: Predicted protein; n=1; Nematostella ve... 49 1e-04
UniRef50_Q4QRL6 Cluster: Hairy-related 12; n=2; Danio rerio|Rep:... 48 1e-04
UniRef50_Q9W7B6 Cluster: BHLH-WRPW transcription factor ESR-5; n... 48 2e-04
UniRef50_Q4S814 Cluster: Chromosome 9 SCAF14710, whole genome sh... 48 2e-04
UniRef50_UPI00015B47F2 Cluster: PREDICTED: similar to RT01017p; ... 47 3e-04
UniRef50_Q6QB00 Cluster: Her/Hey-like protein; n=2; Clupeocephal... 47 5e-04
UniRef50_Q6V6Y9 Cluster: Hairy H protein; n=2; Coelomata|Rep: Ha... 47 5e-04
UniRef50_Q9BYE0 Cluster: Transcription factor HES-7; n=11; Theri... 46 6e-04
UniRef50_Q2TP33 Cluster: Her5; n=1; Oryzias latipes|Rep: Her5 - ... 46 8e-04
UniRef50_A7SMU2 Cluster: Predicted protein; n=1; Nematostella ve... 46 8e-04
UniRef50_Q5TYJ1 Cluster: ENSANGP00000029214; n=1; Anopheles gamb... 33 8e-04
UniRef50_Q4W593 Cluster: ESR4; n=3; Xenopus|Rep: ESR4 - Xenopus ... 46 0.001
UniRef50_Q53U32 Cluster: Enhancer of split related protein 3/7b;... 45 0.001
UniRef50_Q2TP34 Cluster: Her1-11; n=1; Oryzias latipes|Rep: Her1... 45 0.002
UniRef50_A3KQ56 Cluster: Hairy-related 1; n=3; Danio rerio|Rep: ... 44 0.004
UniRef50_O16853 Cluster: Lin-22; n=2; Caenorhabditis|Rep: Lin-22... 44 0.004
UniRef50_UPI0000D5710A Cluster: PREDICTED: similar to CG10446-PA... 43 0.006
UniRef50_UPI00015A7FE8 Cluster: hairy-related 1; n=3; Euteleosto... 43 0.006
UniRef50_Q5D212 Cluster: Hairy and enhancer of split 5; n=10; Te... 42 0.013
UniRef50_Q693N2 Cluster: Hairy; n=1; Clogmia albipunctata|Rep: H... 42 0.013
UniRef50_Q504H7 Cluster: Her5 protein; n=3; Danio rerio|Rep: Her... 42 0.017
UniRef50_Q96HZ4-2 Cluster: Isoform 2 of Q96HZ4 ; n=2; Catarrhini... 41 0.022
UniRef50_Q90Z13 Cluster: Enhancer of split related 2; n=2; Xenop... 41 0.030
UniRef50_Q6W4T8 Cluster: Her11; n=3; Danio rerio|Rep: Her11 - Da... 41 0.030
UniRef50_A7S155 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.030
UniRef50_Q53U31 Cluster: Enhancer of split related protein 1b; n... 40 0.039
UniRef50_Q4S832 Cluster: Chromosome 9 SCAF14710, whole genome sh... 40 0.068
UniRef50_A6NFD8 Cluster: Uncharacterized protein ENSP00000343464... 33 0.098
UniRef50_Q9PTN9 Cluster: Enhancer of split related epidermal pro... 38 0.16
UniRef50_Q4V986 Cluster: Her4.2 protein; n=8; Danio rerio|Rep: H... 38 0.21
UniRef50_UPI0000360D97 Cluster: Transcription factor HES-5 (Hair... 38 0.28
UniRef50_Q5TA89 Cluster: Transcription factor HES-5; n=11; Amnio... 38 0.28
UniRef50_Q5TGS1 Cluster: Transcription factor HES-3; n=11; Euthe... 38 0.28
UniRef50_Q90464 Cluster: HER-2 protein; n=1; Danio rerio|Rep: HE... 37 0.36
UniRef50_Q1L7T5 Cluster: Her4; n=5; Percomorpha|Rep: Her4 - Oryz... 37 0.36
UniRef50_Q16SR7 Cluster: Class b basic helix-loop-helix protein;... 37 0.36
UniRef50_Q693M9 Cluster: Hairy; n=1; Coboldia fuscipes|Rep: Hair... 35 1.5
UniRef50_Q5KHD0 Cluster: Putative uncharacterized protein; n=2; ... 35 1.9
UniRef50_Q9VGZ5 Cluster: CG17100-PA; n=4; Sophophora|Rep: CG1710... 34 3.4
UniRef50_A7IHQ2 Cluster: SMC domain protein; n=1; Xanthobacter a... 33 4.5
UniRef50_Q4WNJ9 Cluster: Peptide alpha-N-acetyltransferase Nat2,... 33 7.8
UniRef50_A4REQ7 Cluster: Putative uncharacterized protein; n=1; ... 33 7.8
>UniRef50_Q7Q0A0 Cluster: ENSANGP00000020090; n=3;
Endopterygota|Rep: ENSANGP00000020090 - Anopheles
gambiae str. PEST
Length = 210
Score = 193 bits (470), Expect = 4e-48
Identities = 92/125 (73%), Positives = 101/125 (80%)
Frame = +1
Query: 112 QPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
+P+SRTYQYRKVM PMLER RRARINRCLDEL ELMVSALQSEG NV KLEKADILELTV
Sbjct: 6 EPLSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 65
Query: 292 XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRL 471
NP +D DRFRAGFTHAA EVSRCLAS PGVD++LGT+LMTHLGHRL
Sbjct: 66 RHLHKLRRQQRLAANPVLDADRFRAGFTHAANEVSRCLASTPGVDIKLGTKLMTHLGHRL 125
Query: 472 NEMQR 486
N++ +
Sbjct: 126 NDLDK 130
>UniRef50_Q17DN9 Cluster: Enhancer of split protein, putative; n=3;
Endopterygota|Rep: Enhancer of split protein, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 229
Score = 190 bits (463), Expect = 2e-47
Identities = 91/125 (72%), Positives = 100/125 (80%)
Frame = +1
Query: 112 QPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
+P+SRTYQYRKVM PMLER RRARINRCLDEL ELMVSALQSEG NV KLEKADILELTV
Sbjct: 23 EPLSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVSKLEKADILELTV 82
Query: 292 XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRL 471
NP +D DRFRAGFTHAA EVSRCLAS GVD++LGT+LMTHLGHRL
Sbjct: 83 RHLHKLRRQQRLTVNPVIDADRFRAGFTHAANEVSRCLASTQGVDIKLGTKLMTHLGHRL 142
Query: 472 NEMQR 486
N++ +
Sbjct: 143 NDLDK 147
>UniRef50_Q01070 Cluster: Enhancer of split mgamma protein
(E(spl)mgamma); n=13; Drosophila|Rep: Enhancer of split
mgamma protein (E(spl)mgamma) - Drosophila melanogaster
(Fruit fly)
Length = 205
Score = 142 bits (344), Expect = 7e-33
Identities = 72/128 (56%), Positives = 89/128 (69%), Gaps = 4/128 (3%)
Frame = +1
Query: 118 VSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVX- 294
+S+TYQYRKVM PMLER RRARIN+CLDEL +LMV+ L+SEG +V +LEKADILELTV
Sbjct: 9 MSKTYQYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTH 68
Query: 295 ---XXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGH 465
+ FR+G+ HA EVSR L+ +PG++V LGTQLMTHLG
Sbjct: 69 LQKMKQQRQHKRASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQ 128
Query: 466 RLNEMQRA 489
RLN++Q A
Sbjct: 129 RLNQIQPA 136
>UniRef50_Q01069 Cluster: Enhancer of split mbeta protein
(E(spl)mbeta); n=5; Drosophila|Rep: Enhancer of split
mbeta protein (E(spl)mbeta) - Drosophila melanogaster
(Fruit fly)
Length = 195
Score = 140 bits (338), Expect = 3e-32
Identities = 73/134 (54%), Positives = 90/134 (67%), Gaps = 12/134 (8%)
Frame = +1
Query: 118 VSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV-- 291
+S+TYQYRKVM PMLER RRARIN+CLDEL ++MV L EG ++ +LEKADILELTV
Sbjct: 7 MSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEH 66
Query: 292 -----XXXXXXXXXXXXXXNPTVD-----VDRFRAGFTHAAXEVSRCLASIPGVDVRLGT 441
+P+ D + FRAG+ HAA EVS+ LA++PGV V LGT
Sbjct: 67 MKKLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGT 126
Query: 442 QLMTHLGHRLNEMQ 483
QLM+HLGHRLN +Q
Sbjct: 127 QLMSHLGHRLNYLQ 140
>UniRef50_Q01071 Cluster: Enhancer of split mdelta protein
(E(spl)mdelta); n=4; Sophophora|Rep: Enhancer of split
mdelta protein (E(spl)mdelta) - Drosophila melanogaster
(Fruit fly)
Length = 173
Score = 118 bits (284), Expect = 1e-25
Identities = 61/135 (45%), Positives = 88/135 (65%), Gaps = 4/135 (2%)
Frame = +1
Query: 94 VAEDGPQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKAD 273
+A G + +++T YRKV P+LER RRAR+N LDEL +L+V + ++G V KLEKAD
Sbjct: 1 MAVQGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKAD 60
Query: 274 ILELTVXXXXXXXXXXXXX-XNP---TVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGT 441
ILELTV +P V++D+FRAG+T AA EVS +++PG+D++ GT
Sbjct: 61 ILELTVNYLKAQQQQRVANPQSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGT 120
Query: 442 QLMTHLGHRLNEMQR 486
LM LGH+L +M++
Sbjct: 121 HLMKQLGHQLKDMKQ 135
>UniRef50_Q01068 Cluster: Enhancer of split m3 protein (E(spl)m3);
n=11; Sophophora|Rep: Enhancer of split m3 protein
(E(spl)m3) - Drosophila melanogaster (Fruit fly)
Length = 224
Score = 103 bits (247), Expect = 4e-21
Identities = 59/135 (43%), Positives = 78/135 (57%), Gaps = 13/135 (9%)
Frame = +1
Query: 118 VSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV-- 291
+S+TYQYRKVM P+LER RRARIN+CLD+L +LMV LQ EG +V +LEKADILELTV
Sbjct: 5 MSKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDH 64
Query: 292 -----------XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLG 438
T V+ FR+G+ HAA ++++ L D +G
Sbjct: 65 MRKLKQRGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTD-EIG 123
Query: 439 TQLMTHLGHRLNEMQ 483
++M L RL E+Q
Sbjct: 124 RKIMKFLSTRLIELQ 138
>UniRef50_Q9N6W7 Cluster: HLHmdelta protein; n=1; Drosophila
hydei|Rep: HLHmdelta protein - Drosophila hydei (Fruit
fly)
Length = 158
Score = 100 bits (240), Expect = 3e-20
Identities = 55/131 (41%), Positives = 81/131 (61%)
Frame = +1
Query: 94 VAEDGPQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKAD 273
+A +G + +++T YRKV P+LER RRAR+N LDEL +L+V + ++G V KLEKAD
Sbjct: 1 MAVEGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKAD 60
Query: 274 ILELTVXXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMT 453
ILELTV + + + +T AA EVS +++PGVD++ GT LM
Sbjct: 61 ILELTVNY---------------LKTQQQQRRYTQAAYEVSHIFSTVPGVDLKFGTHLMK 105
Query: 454 HLGHRLNEMQR 486
LGH+L +M++
Sbjct: 106 QLGHQLKDMKQ 116
>UniRef50_P13098 Cluster: Enhancer of split m8 protein (E(spl)m8);
n=40; Drosophila|Rep: Enhancer of split m8 protein
(E(spl)m8) - Drosophila melanogaster (Fruit fly)
Length = 179
Score = 86.2 bits (204), Expect = 6e-16
Identities = 46/123 (37%), Positives = 70/123 (56%), Gaps = 1/123 (0%)
Frame = +1
Query: 121 SRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXX 300
++T Y+KV PMLER RRAR+N+CLD L L+ +G + +++KA++LE V
Sbjct: 5 TKTQIYQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDG--ILRMDKAEMLESAVIFM 62
Query: 301 XXXXX-XXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRLNE 477
++ +D F+ G+ +A EVSR +AS PG+ V LG +MTHLG
Sbjct: 63 RQQKTPKKVAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKN 122
Query: 478 MQR 486
+Q+
Sbjct: 123 LQQ 125
>UniRef50_UPI00003BFC0E Cluster: PREDICTED: similar to deadpan
CG8704-PA; n=2; Apocrita|Rep: PREDICTED: similar to
deadpan CG8704-PA - Apis mellifera
Length = 446
Score = 85.4 bits (202), Expect = 1e-15
Identities = 47/132 (35%), Positives = 76/132 (57%), Gaps = 3/132 (2%)
Frame = +1
Query: 100 EDGPQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADIL 279
E QP + R+ P++E+ RRARIN+CLDEL L++ A++ + KLEKADIL
Sbjct: 9 ESHAQPGMTKAELRRSNKPIMEKRRRARINQCLDELKSLILEAMKKDPARHSKLEKADIL 68
Query: 280 ELTV---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLM 450
E+TV +P V + +FR+GF+ A EVSR ++ + VD + +L+
Sbjct: 69 EMTVKHLQAVQRQQLSTAVATDPAV-LTKFRSGFSECATEVSRYVSHLENVDPVVKQRLV 127
Query: 451 THLGHRLNEMQR 486
+HL + ++ +Q+
Sbjct: 128 SHLNNCVSNLQQ 139
>UniRef50_Q26263 Cluster: Protein deadpan; n=3; Protostomia|Rep:
Protein deadpan - Drosophila melanogaster (Fruit fly)
Length = 435
Score = 81.8 bits (193), Expect = 1e-14
Identities = 45/129 (34%), Positives = 72/129 (55%), Gaps = 3/129 (2%)
Frame = +1
Query: 109 PQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELT 288
P +S+ + RK P++E+ RRARIN CL+EL L++ A++ + KLEKADILE+T
Sbjct: 32 PNGLSKA-ELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMT 90
Query: 289 V---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
V +P+V V +F+ GF A EV+R ++ + G+D + +L HL
Sbjct: 91 VKHLQSVQRQQLNMAIQSDPSV-VQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHL 149
Query: 460 GHRLNEMQR 486
N +++
Sbjct: 150 NQCANSLEQ 158
>UniRef50_Q14469 Cluster: Transcription factor HES-1; n=52;
Euteleostomi|Rep: Transcription factor HES-1 - Homo
sapiens (Human)
Length = 280
Score = 79.4 bits (187), Expect = 7e-14
Identities = 45/134 (33%), Positives = 75/134 (55%), Gaps = 3/134 (2%)
Frame = +1
Query: 88 IQVAEDGPQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEK 267
+ D P+ S ++RK P++E+ RRARIN L +L L++ AL+ + KLEK
Sbjct: 21 VNTTPDKPKTAS---EHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEK 77
Query: 268 ADILELTV---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLG 438
ADILE+TV +P+V + ++RAGF+ EV+R L++ GV+ +
Sbjct: 78 ADILEMTVKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVR 136
Query: 439 TQLMTHLGHRLNEM 480
T+L+ HL + + ++
Sbjct: 137 TRLLGHLANCMTQI 150
>UniRef50_UPI00003C06C0 Cluster: PREDICTED: similar to Protein
hairy; n=1; Apis mellifera|Rep: PREDICTED: similar to
Protein hairy - Apis mellifera
Length = 363
Score = 79.0 bits (186), Expect = 9e-14
Identities = 46/123 (37%), Positives = 69/123 (56%), Gaps = 3/123 (2%)
Frame = +1
Query: 124 RTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV---X 294
R+ + R+ P++E+ RRARIN CL++L L++ A++ + KLEKADILE+TV
Sbjct: 45 RSGENRRSNKPIMEKRRRARINNCLNDLKTLILDAMKKDPARHSKLEKADILEMTVKHLE 104
Query: 295 XXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRLN 474
+P V +++FRAGFT A EV R PG+D + +LM HL L
Sbjct: 105 TLQRQQVALAAATDPNV-LNKFRAGFTECAGEVGR----FPGLDASVKRRLMAHLASCLG 159
Query: 475 EMQ 483
++
Sbjct: 160 PVE 162
>UniRef50_Q90468 Cluster: HER-6 protein; n=4; Clupeocephala|Rep:
HER-6 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 334
Score = 79.0 bits (186), Expect = 9e-14
Identities = 44/127 (34%), Positives = 70/127 (55%), Gaps = 3/127 (2%)
Frame = +1
Query: 109 PQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELT 288
P ++RK P++E+ RRARIN L +L L++ AL+ + KLEKADILE+T
Sbjct: 89 PDKPKTASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMT 148
Query: 289 V---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
V +PTV + ++RAGF+ EV+R L++ GV+ + T+L+ HL
Sbjct: 149 VKHLRNMQRAQMTAALNTDPTV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 207
Query: 460 GHRLNEM 480
+ ++
Sbjct: 208 ASCMTQI 214
>UniRef50_Q9NFW8 Cluster: DNA-binding-protein hairy; n=2;
Entelegynae|Rep: DNA-binding-protein hairy - Cupiennius
salei (Wandering spider)
Length = 335
Score = 78.2 bits (184), Expect = 2e-13
Identities = 45/124 (36%), Positives = 70/124 (56%), Gaps = 3/124 (2%)
Frame = +1
Query: 118 VSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV-- 291
V++ + R+ P++E+ RRARIN L EL L++ AL+ + KLEKADILE+TV
Sbjct: 53 VTKCSETRRSTKPIMEKRRRARINNSLSELKNLILDALKKDNARHSKLEKADILEMTVKH 112
Query: 292 -XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHR 468
+P++ + +FRAGF A EV+R + S+ G+D + +L+ HL +
Sbjct: 113 LQNLQMQQQQQQLTPDPSM-MAKFRAGFAECANEVNRFMGSMEGIDHTIRQRLLNHLANC 171
Query: 469 LNEM 480
L M
Sbjct: 172 LTGM 175
>UniRef50_UPI00015B599D Cluster: PREDICTED: similar to hairy
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to hairy protein - Nasonia vitripennis
Length = 376
Score = 77.0 bits (181), Expect = 4e-13
Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 3/120 (2%)
Frame = +1
Query: 109 PQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELT 288
P R+ + R+ P++E+ RRARIN CL++L L++ A++ + KLEKADILE+T
Sbjct: 47 PAAPRRSSENRRSNKPIMEKRRRARINNCLNDLKALILDAMKKDPARHSKLEKADILEMT 106
Query: 289 V---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
V +P V +++FRAGFT A EV R PG++ + +L+ HL
Sbjct: 107 VKHLETLQRQQVALASATDPNV-LNKFRAGFTECANEVGR----FPGLEASMKRRLLAHL 161
>UniRef50_Q6V6Z0 Cluster: Hairy G protein; n=1; Branchiostoma
floridae|Rep: Hairy G protein - Branchiostoma floridae
(Florida lancelet) (Amphioxus)
Length = 267
Score = 76.6 bits (180), Expect = 5e-13
Identities = 40/112 (35%), Positives = 63/112 (56%), Gaps = 2/112 (1%)
Frame = +1
Query: 130 YQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXX 309
YQ RK P++E+ RRARIN L+EL L++ +++ + KLEKADILE+ V
Sbjct: 13 YQSRKSSKPLMEKRRRARINSSLNELKNLILDTYKNDSTHHSKLEKADILEIAVKHVRSL 72
Query: 310 XXXXXXXXNPT--VDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
T + R+RAG++ EV+R + ++ GVD ++ +L+ HL
Sbjct: 73 QRQQMAAAVSTDPAALGRYRAGYSRCRAEVARFMGTVDGVDPQVRQKLLNHL 124
>UniRef50_Q4H3N9 Cluster: Transcription factor protein; n=3;
Eumetazoa|Rep: Transcription factor protein - Ciona
intestinalis (Transparent sea squirt)
Length = 522
Score = 76.6 bits (180), Expect = 5e-13
Identities = 44/130 (33%), Positives = 71/130 (54%), Gaps = 3/130 (2%)
Frame = +1
Query: 106 GPQPVSRTY-QYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILE 282
G + TY + +K P++E+ RRARIN L+EL +++ AL+ + KLEKADILE
Sbjct: 19 GDVDLGGTYIERQKSSKPIMEKRRRARINSSLNELKSILLEALKKDSTRHSKLEKADILE 78
Query: 283 LTV--XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTH 456
+TV ++++++AGF EV R L++ GV V + T+L+ H
Sbjct: 79 MTVKYLKNVERQRLSVSLSIDPAEINQYKAGFNECRNEVMRFLSTCEGVTVDVRTRLLNH 138
Query: 457 LGHRLNEMQR 486
L L+ +Q+
Sbjct: 139 LATCLHSIQK 148
>UniRef50_Q8T306 Cluster: Helix-loop-helix transcription factor;
n=2; Tribolium castaneum|Rep: Helix-loop-helix
transcription factor - Tribolium castaneum (Red flour
beetle)
Length = 249
Score = 76.2 bits (179), Expect = 6e-13
Identities = 47/124 (37%), Positives = 68/124 (54%), Gaps = 3/124 (2%)
Frame = +1
Query: 124 RTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV---X 294
R R+ P++E+ RRARIN L+EL L++ A++ + KLEKADILE+TV
Sbjct: 30 RVSDNRRSNKPIMEKRRRARINNSLNELKTLILDAMKKDPARHSKLEKADILEMTVKHLQ 89
Query: 295 XXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRLN 474
+P+V V +FRAGF+ A EV R PG+D + +L+ HL LN
Sbjct: 90 NLQRQQAAMSAATDPSV-VSKFRAGFSECASEVGR----FPGLDPVVKRRLLQHLASCLN 144
Query: 475 EMQR 486
+ Q+
Sbjct: 145 QGQK 148
>UniRef50_Q16NK4 Cluster: Hairy protein; n=4; Diptera|Rep: Hairy
protein - Aedes aegypti (Yellowfever mosquito)
Length = 343
Score = 75.8 bits (178), Expect = 8e-13
Identities = 51/135 (37%), Positives = 73/135 (54%), Gaps = 4/135 (2%)
Frame = +1
Query: 82 SRIQVAEDGPQPV-SRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXK 258
S+I AE QPV R R+ P++E+ RRARIN CL+EL L++ A++ + K
Sbjct: 19 SQISSAE---QPVVKRPSDNRRSNKPIMEKRRRARINNCLNELKTLILDAMKKDPARHSK 75
Query: 259 LEKADILELTV---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDV 429
LEKADILE+TV +P V +++F+AGF A EVSR P +D
Sbjct: 76 LEKADILEMTVKHLENLQRQQNAMSQATDPNV-MNKFKAGFNECAQEVSR----FPDIDP 130
Query: 430 RLGTQLMTHLGHRLN 474
+L+ HL + +N
Sbjct: 131 MTRRRLLAHLSNCIN 145
>UniRef50_UPI0001554A1E Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 287
Score = 75.4 bits (177), Expect = 1e-12
Identities = 41/112 (36%), Positives = 65/112 (58%), Gaps = 3/112 (2%)
Frame = +1
Query: 154 PMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV---XXXXXXXXXXX 324
P++E+ RRARIN L +L L++ AL+ + KLEKADILE+TV
Sbjct: 22 PIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAA 81
Query: 325 XXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRLNEM 480
+PTV + ++RAGF+ EV+R L++ GV+ + T+L+ HL + ++
Sbjct: 82 LSSDPTV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLASCMTQI 132
>UniRef50_Q56KF1 Cluster: Enhancer of split m5 protein; n=2;
Drosophila melanogaster|Rep: Enhancer of split m5
protein - Drosophila melanogaster (Fruit fly)
Length = 129
Score = 74.9 bits (176), Expect = 1e-12
Identities = 56/121 (46%), Positives = 78/121 (64%)
Frame = +1
Query: 118 VSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXX 297
VS+T Y KV P+LER RRAR+N+CLD L + +V+ Q + + +++KA++LE
Sbjct: 11 VSKTQHYLKVKKPLLERQRRARMNKCLDTL-KTLVAEFQGDDA-ILRMDKAEMLE-AAXX 67
Query: 298 XXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRLNE 477
D F+ G+ +A E+SR +A P + V +G +MTHLG
Sbjct: 68 XXXXXXXXXXXXXXXXXXDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQR 127
Query: 478 M 480
M
Sbjct: 128 M 128
>UniRef50_A7RU73 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 74.1 bits (174), Expect = 3e-12
Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 3/110 (2%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK PM+E+ RRARIN+ L+EL L++ A++ + KLEKADILE+TV
Sbjct: 18 RKSSKPMMEKRRRARINQSLNELKILILEAMKKDTSCYSKLEKADILEMTVKYLRAMKTT 77
Query: 319 XXXXXNPTVD---VDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
D V ++RAGF A EV+R + VD+++ T++++HL
Sbjct: 78 QQLTGIVPSDPSSVAQYRAGFNECALEVTRYFMANDNVDLQMKTRILSHL 127
>UniRef50_Q208Q9 Cluster: AmphiHairyA; n=6; Branchiostoma
floridae|Rep: AmphiHairyA - Branchiostoma floridae
(Florida lancelet) (Amphioxus)
Length = 300
Score = 73.3 bits (172), Expect = 5e-12
Identities = 42/111 (37%), Positives = 61/111 (54%), Gaps = 2/111 (1%)
Frame = +1
Query: 133 QYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV--XXXXX 306
Q RK P++E+ RRARIN L++L L++ AL+ + KLEKADILE+TV
Sbjct: 19 QRRKSSKPIMEKRRRARINDSLNQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQ 78
Query: 307 XXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
V + ++RAG++ EVSR L GVD ++ +L+ HL
Sbjct: 79 RQQIADAVIRDPVALSKYRAGYSECMTEVSRFLTGSDGVDGQVQQRLLGHL 129
>UniRef50_A2TIR6 Cluster: Splhairy; n=1; Panulirus argus|Rep:
Splhairy - Panulirus argus (Spiny lobster)
Length = 253
Score = 73.3 bits (172), Expect = 5e-12
Identities = 41/109 (37%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV-XXXXXXXX 315
R+ P++E+ RR RIN CL++L L++ L+ + KLEKADILE+TV
Sbjct: 20 RRTNKPIMEKKRRQRINDCLNQLKNLVLEGLKKDPSRYNKLEKADILEMTVRHVQALHRH 79
Query: 316 XXXXXXNPTVD-VDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
P VD +FRAGF H A EV R L V ++++ HL
Sbjct: 80 ESALSRQPPVDAAAKFRAGFAHCAAEVGRFLEGDTSVSAGQRSRILLHL 128
>UniRef50_Q6V6Z2 Cluster: Hairy E protein; n=3; Branchiostoma
floridae|Rep: Hairy E protein - Branchiostoma floridae
(Florida lancelet) (Amphioxus)
Length = 345
Score = 71.7 bits (168), Expect = 1e-11
Identities = 44/119 (36%), Positives = 63/119 (52%), Gaps = 3/119 (2%)
Frame = +1
Query: 112 QPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
Q SR + RK P++E+ RRARIN L++L L++ AL+ + KLEKADILE+TV
Sbjct: 4 QKDSRPSEGRKSSKPIMEKRRRARINDSLNQLKTLILDALKKDSSRHSKLEKADILEMTV 63
Query: 292 ---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
+P V + ++RAGF EVS L S V+ + +L+ HL
Sbjct: 64 KHLRNLQRQHVAAAVSTDPNV-LGQYRAGFNECMTEVSSFLGSASTVETEVHQRLLNHL 121
>UniRef50_Q29G34 Cluster: GA19235-PA; n=1; Drosophila
pseudoobscura|Rep: GA19235-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 217
Score = 71.3 bits (167), Expect = 2e-11
Identities = 35/60 (58%), Positives = 42/60 (70%)
Frame = +1
Query: 112 QPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
Q +SR+ +YRKVM P+LER RRARIN CLDEL ++ E + KLEKADILEL V
Sbjct: 81 QGLSRSSEYRKVMKPLLERKRRARINNCLDELKIIIADLAHMETTGLNKLEKADILELAV 140
>UniRef50_P29303 Cluster: Protein hairy; n=2; Muscomorpha|Rep:
Protein hairy - Drosophila virilis (Fruit fly)
Length = 378
Score = 71.3 bits (167), Expect = 2e-11
Identities = 43/115 (37%), Positives = 63/115 (54%), Gaps = 3/115 (2%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV---XXXXXX 309
R+ P++E+ RRARIN CL+EL L++ A + + KLEKADILE TV
Sbjct: 38 RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQ 97
Query: 310 XXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRLN 474
+P + +++F+AGF A EVSR PG+D +L+ HL + +N
Sbjct: 98 QAAMQQAADPKI-INKFKAGFADCANEVSR----FPGLDSTQRRRLLQHLSNCIN 147
>UniRef50_Q17DP5 Cluster: Hairy protein; n=2; Culicidae|Rep: Hairy
protein - Aedes aegypti (Yellowfever mosquito)
Length = 343
Score = 70.1 bits (164), Expect = 4e-11
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 3/112 (2%)
Frame = +1
Query: 133 QYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV---XXXX 303
+ RK P++E+ RRARIN L++L L++ A++ + KLEKADIL+LTV
Sbjct: 27 EIRKTNKPIMEKKRRARINNYLNDLKALLLDAMKKDPIRHSKLEKADILDLTVKHLQDLE 86
Query: 304 XXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
+PTV VD+F++GF E+ + L ++ VD + ++ HL
Sbjct: 87 RRKLAIAMAVDPTV-VDKFKSGFNECIEEIDKYLNTVSSVDGGMKQRISNHL 137
>UniRef50_P14003 Cluster: Protein hairy; n=3; Sophophora|Rep:
Protein hairy - Drosophila melanogaster (Fruit fly)
Length = 337
Score = 69.3 bits (162), Expect = 7e-11
Identities = 42/115 (36%), Positives = 62/115 (53%), Gaps = 3/115 (2%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV---XXXXXX 309
R+ P++E+ RRARIN CL+EL L++ A + + KLEKADILE TV
Sbjct: 32 RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQ 91
Query: 310 XXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRLN 474
+P + V++F+AGF EVSR PG++ +L+ HL + +N
Sbjct: 92 QAAMQQAADPKI-VNKFKAGFADCVNEVSR----FPGIEPAQRRRLLQHLSNCIN 141
>UniRef50_A7RYX4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 213
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/107 (39%), Positives = 53/107 (49%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK PM+E+ RRARIN L+EL L++ L + K+EKADILE+TV
Sbjct: 20 RKAKKPMMEKLRRARINDSLNELKVLVLELLNKDASRYSKMEKADILEMTVGYLRAAQRI 79
Query: 319 XXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
T D FRAGF A EVS L+ L L++HL
Sbjct: 80 EKRTQGSTPPSD-FRAGFNACAVEVSNRLSPADANTDNLRETLLSHL 125
>UniRef50_Q9Y543 Cluster: Transcription factor HES-2; n=14;
Theria|Rep: Transcription factor HES-2 - Homo sapiens
(Human)
Length = 173
Score = 68.9 bits (161), Expect = 1e-10
Identities = 38/120 (31%), Positives = 61/120 (50%)
Frame = +1
Query: 109 PQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELT 288
P+ + RK + P+LE+ RRARIN+ L +L L++ L E N KLEKAD+LE+T
Sbjct: 4 PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63
Query: 289 VXXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHR 468
V P + D +R G++ ++R L + ++ + +L+ HL R
Sbjct: 64 VRFLQELPASSWPTAAP-LPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRR 122
>UniRef50_Q9DEU7 Cluster: Transcription factor Her-8b; n=3; Danio
rerio|Rep: Transcription factor Her-8b - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 221
Score = 67.3 bits (157), Expect = 3e-10
Identities = 44/138 (31%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Frame = +1
Query: 103 DGPQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILE 282
+GP+ + RK+ P++E+ RR RIN L++L +MV A + KLEKAD+LE
Sbjct: 8 NGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAY---NLDQSKLEKADVLE 64
Query: 283 LTV--XXXXXXXXXXXXXXNPTVDVD---RFRAGFTHAAXEVSRCLASIPGVDVRLGTQL 447
+TV +P + R+ +G+ EV L S PG+D LG +L
Sbjct: 65 ITVQHMENLQRGHGQGGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARL 124
Query: 448 MTHLGHRLNEMQRAXAGT 501
+ HL L + +GT
Sbjct: 125 LNHLLKSLPHISTEPSGT 142
>UniRef50_UPI0000D57461 Cluster: PREDICTED: similar to CG8704-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG8704-PA - Tribolium castaneum
Length = 371
Score = 66.1 bits (154), Expect = 7e-10
Identities = 40/117 (34%), Positives = 62/117 (52%), Gaps = 3/117 (2%)
Frame = +1
Query: 133 QYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV---XXXX 303
+ RK P++E+ RRARIN CL+E+ L++ A+ + KLEKADILE+ V
Sbjct: 23 ELRKTHKPIMEKRRRARINHCLNEIKTLILEAMNKDPARHSKLEKADILEMAVKHLQNVQ 82
Query: 304 XXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRLN 474
+P+V + +F++GF A E+ R S VD L ++ +HL +N
Sbjct: 83 RQQLAVAMASDPSV-LRKFKSGFNECANEIDR-FVSQSEVDDGLKDRMRSHLQKCIN 137
>UniRef50_Q1ECY5 Cluster: LOC565269 protein; n=3; Danio rerio|Rep:
LOC565269 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 223
Score = 64.1 bits (149), Expect = 3e-09
Identities = 40/110 (36%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK+ P++ER RR RIN CLD+L E +V + + KLEKADILE+TV
Sbjct: 35 RKLRKPLIERKRRERINLCLDQLRETVVGVFKPD---QSKLEKADILEMTV--KHLQNIQ 89
Query: 319 XXXXXNPTVDV---DRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
+P ++ R+ G+ EV L S +D LG++L HL
Sbjct: 90 SSRVSDPVLNTGARQRYSTGYIQCMQEVHNLLHSCDWMDKTLGSRLFNHL 139
>UniRef50_Q0VFM2 Cluster: Hairy and enhancer of split 6 gene 2; n=6;
Coelomata|Rep: Hairy and enhancer of split 6 gene 2 -
Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 189
Score = 64.1 bits (149), Expect = 3e-09
Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK+ P++ER RR RIN CL++L E ++ A + KLEKADILE+TV
Sbjct: 18 RKLRKPLIERKRRERINTCLEQLKETVIKAFH---LDQSKLEKADILEMTVRHLQNIQKS 74
Query: 319 XXXXXNPTVDVD---RFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
VD RF G+ E+ L + +D LG +L+ HL
Sbjct: 75 KSTGEPSQGSVDAQQRFSTGYIQCMHELHSLLLTCDWMDPALGARLLNHL 124
>UniRef50_Q9VWX7 Cluster: CG5927-PA; n=1; Drosophila
melanogaster|Rep: CG5927-PA - Drosophila melanogaster
(Fruit fly)
Length = 149
Score = 63.7 bits (148), Expect = 4e-09
Identities = 27/57 (47%), Positives = 40/57 (70%)
Frame = +1
Query: 121 SRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
SR++QYR+V PM+ER RR+RINRCLD + +L+ +G + K++ D+LEL V
Sbjct: 16 SRSHQYREVFKPMMERKRRSRINRCLDFIKDLLQEVSHLDGETMAKMDMGDVLELAV 72
>UniRef50_Q6JJ70 Cluster: Hairy/enhancer of split; n=1;
Strongylocentrotus purpuratus|Rep: Hairy/enhancer of
split - Strongylocentrotus purpuratus (Purple sea
urchin)
Length = 400
Score = 62.9 bits (146), Expect = 6e-09
Identities = 43/118 (36%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK P +E+ RRARIN L +L L++ A + KLEKADILE+TV
Sbjct: 25 RKSSKPQMEKRRRARINDSLGQLKALILEATNKDSSRHSKLEKADILEMTVKHLRNIQRN 84
Query: 319 XXX---XXNPTVDVDRFRAGFTHAAXEVSRC---LASIPGVDVRLGTQLMTHLGHRLN 474
+P + V RFR G++ EV+R + +I G D+RL L+ HL + N
Sbjct: 85 QLTGPLSSDPNM-VSRFRQGYSECVHEVARFFTNIENIGGPDMRL--SLINHLANTCN 139
>UniRef50_Q7KM13 Cluster: Hairy/enhancer-of-split related with YRPW
motif protein; n=2; Sophophora|Rep:
Hairy/enhancer-of-split related with YRPW motif protein
- Drosophila melanogaster (Fruit fly)
Length = 425
Score = 62.1 bits (144), Expect = 1e-08
Identities = 44/129 (34%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Frame = +1
Query: 112 QPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
+P S RK ++E+ RR RIN L EL L+ SA + +G KLEKA+IL+LTV
Sbjct: 92 EPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEKQGS--AKLEKAEILQLTV 149
Query: 292 XXXXXXXXXXXXXXN---PTVDVDRFRAGFTHAAXEVSRCLASIPGVDVR--LGTQLMTH 456
+ V +D GF A EV+R L +I G+D++ L +LM+H
Sbjct: 150 EHLKSLQSKTLDSLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSH 209
Query: 457 LGHRLNEMQ 483
L + + + +
Sbjct: 210 LQYFVQQRE 218
>UniRef50_UPI000065D5D5 Cluster: Transcription factor HES-3 (Hairy
and enhancer of split 3).; n=1; Takifugu rubripes|Rep:
Transcription factor HES-3 (Hairy and enhancer of split
3). - Takifugu rubripes
Length = 271
Score = 61.3 bits (142), Expect = 2e-08
Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 3/124 (2%)
Frame = +1
Query: 97 AEDGPQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADI 276
+ED P+ VS +KV P++E+ RRARIN+CLD+L ++++ + S KLEKADI
Sbjct: 7 SEDPPKHVSG----KKVSKPLMEKKRRARINKCLDQL-KILLESYYSTSIRKRKLEKADI 61
Query: 277 LELTVXXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLA---SIPGVDVRLGTQL 447
LELTV + D ++GF A V + L S+ G+D + +QL
Sbjct: 62 LELTVNHLRNLQKHQSCNIASSESSDH-QSGFRRCAANVDQFLLMADSVNGIDRWMLSQL 120
Query: 448 MTHL 459
L
Sbjct: 121 SAKL 124
>UniRef50_Q4H3P0 Cluster: Transcription factor protein; n=1; Ciona
intestinalis|Rep: Transcription factor protein - Ciona
intestinalis (Transparent sea squirt)
Length = 333
Score = 60.5 bits (140), Expect = 3e-08
Identities = 40/116 (34%), Positives = 62/116 (53%), Gaps = 5/116 (4%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNV-XKLEKADILELTV---XXXXX 306
R+ P++E+ RR RIN+ L+EL +++ AL+ + KLEKADILE+TV
Sbjct: 25 RRASKPLMEKRRRERINKSLNELKSILLHALRKDQSTCHSKLEKADILEMTVRYLRGIQR 84
Query: 307 XXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLA-SIPGVDVRLGTQLMTHLGHRL 471
+P+V V ++R G+ EVS L S V + ++L+ HLG+ L
Sbjct: 85 QRMNAAITLDPSV-VSKYRNGYVECKNEVSHFLENSSENVHPDVKSRLINHLGNTL 139
>UniRef50_Q568C3 Cluster: Her3 protein; n=3; Danio rerio|Rep: Her3
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 253
Score = 58.8 bits (136), Expect = 1e-07
Identities = 45/130 (34%), Positives = 60/130 (46%), Gaps = 3/130 (2%)
Frame = +1
Query: 85 RIQVAEDGPQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLE 264
R A ++ +KV P++E+ RRARIN+CL++L L+ SA S KLE
Sbjct: 23 RTMAAASNSAATAKPQNVKKVSKPLMEKKRRARINKCLNQLKSLLESAC-SNNIRKRKLE 81
Query: 265 KADILELTVXXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCL-ASIPGVDVR--L 435
KADILELTV + D + AG+ VS L AS D R +
Sbjct: 82 KADILELTV-KHLRHLQNTKRGLSKACDSAEYHAGYRSCLNTVSHYLRASDTDRDSRSIM 140
Query: 436 GTQLMTHLGH 465
T L + L H
Sbjct: 141 LTNLTSGLNH 150
>UniRef50_Q17LB7 Cluster: Transcription factor Hairy, putative; n=2;
Culicidae|Rep: Transcription factor Hairy, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 298
Score = 58.0 bits (134), Expect = 2e-07
Identities = 44/114 (38%), Positives = 59/114 (51%), Gaps = 7/114 (6%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK ++E+ RR RIN L EL L+ SA + +G KLEKA+IL+LTV
Sbjct: 20 RKRRRGVIEKKRRDRINSSLSELKRLVPSAYEKQGS--AKLEKAEILQLTV--DHLKQLH 75
Query: 319 XXXXXNPTVDVDRFR-----AGFTHAAXEVSRCLASIPGVDVR--LGTQLMTHL 459
+ + D RF GF EV+R L SI G+DV+ L +LM+HL
Sbjct: 76 ARGLDDASYDPQRFAMDYHIIGFRECVAEVARYLVSIEGMDVQDPLRLRLMSHL 129
>UniRef50_Q8T8A9 Cluster: Hairy E(SPL) like bHLH transcription
factor; n=1; Halocynthia roretzi|Rep: Hairy E(SPL) like
bHLH transcription factor - Halocynthia roretzi (Sea
squirt)
Length = 292
Score = 56.8 bits (131), Expect = 4e-07
Identities = 28/51 (54%), Positives = 36/51 (70%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
RK P++E+ RR RINRCLDEL +++ A+ E KLEKADILE+TV
Sbjct: 14 RKTNKPIMEKKRRERINRCLDELKNIVLRAVNEE-SRPNKLEKADILEMTV 63
>UniRef50_Q4H3E4 Cluster: Transcription factor protein; n=1; Ciona
intestinalis|Rep: Transcription factor protein - Ciona
intestinalis (Transparent sea squirt)
Length = 248
Score = 56.8 bits (131), Expect = 4e-07
Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 5/112 (4%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK ++E+ RR RIN L EL ++ +A + G + KLEKA+IL+LTV
Sbjct: 29 RKKRRGVIEKRRRDRINNSLSELRRMIPAASEKHGSS--KLEKAEILQLTVEHLKTLQSA 86
Query: 319 XXXXXNPTVD-----VDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
P +D VD GF EV+R + S+ G+ + L++HL
Sbjct: 87 ISKGYFPFMDVRTMAVDYHSFGFRECVSEVARYMISMDGIQSSVRENLLSHL 138
>UniRef50_UPI000058443F Cluster: PREDICTED: similar to hairy E
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to hairy E protein -
Strongylocentrotus purpuratus
Length = 397
Score = 56.4 bits (130), Expect = 6e-07
Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 6/123 (4%)
Frame = +1
Query: 121 SRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNV--XKLEKADILELTVX 294
SR+++ RK P++E+ RRARIN CL EL + ++ AL E + K EKADILE TV
Sbjct: 8 SRSHEGRKSSKPLMEKRRRARINDCLTEL-QTILDALNPENNSTRQNKREKADILEQTVK 66
Query: 295 XXXXXXXXXXXXX---NPTVDVDRFRAGFTHAAXEVSRCLASIPG-VDVRLGTQLMTHLG 462
+P V +FR+GF V++ L++ G ++ LM+HL
Sbjct: 67 LVKQLRQHGIRGNHPPDPNTQV-QFRSGFNECMATVTQFLSANNGSLNGEAKAGLMSHLA 125
Query: 463 HRL 471
+ L
Sbjct: 126 NSL 128
>UniRef50_A1L3K9 Cluster: LOC100037036 protein; n=2; Xenopus|Rep:
LOC100037036 protein - Xenopus laevis (African clawed
frog)
Length = 222
Score = 56.0 bits (129), Expect = 7e-07
Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 2/109 (1%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
R+ P++E+ RRARIN L EL ++ S+ K+E A++L+LTV
Sbjct: 41 RQTRKPLVEKRRRARINESLQELRGIL-----SDNEFQTKIENAEVLDLTVKRVERILRN 95
Query: 319 XXXXXN--PTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
+ +RF AG+ EV ++S PG+D L +L+ HL
Sbjct: 96 RTAEADRLQREASERFAAGYIQCMHEVHTFVSSCPGIDASLAAELLNHL 144
>UniRef50_Q6P0J1 Cluster: Hairy and enhancer of split 6; n=3; Danio
rerio|Rep: Hairy and enhancer of split 6 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 226
Score = 54.8 bits (126), Expect = 2e-06
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK P++E+ RRARIN L EL L+ ++ K+E A++LE+TV
Sbjct: 20 RKTRKPLVEKKRRARINESLQELRLLL-----ADPDAQVKMENAEVLEMTVKRVESILQN 74
Query: 319 XXXXXNPTVDV--DRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
+ +RF AG+ EV ++S PG+D + L+ HL
Sbjct: 75 KAKEADSVNREANERFAAGYIQCMHEVHTFVSSCPGIDATIAADLLNHL 123
>UniRef50_Q5XHC4 Cluster: LOC495039 protein; n=7; Tetrapoda|Rep:
LOC495039 protein - Xenopus laevis (African clawed frog)
Length = 202
Score = 54.4 bits (125), Expect = 2e-06
Identities = 27/64 (42%), Positives = 40/64 (62%), Gaps = 3/64 (4%)
Frame = +1
Query: 109 PQPVSRTYQ---YRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADIL 279
P+P R + RK + P++E+ RRARIN L++L L++ + + KLEKADIL
Sbjct: 27 PKPGKRNQEASELRKTLKPLMEKRRRARINESLNQLKTLILPLIGKDNSRYSKLEKADIL 86
Query: 280 ELTV 291
E+TV
Sbjct: 87 EMTV 90
>UniRef50_Q5S4J7 Cluster: Enhancer of split complex m5 protein; n=2;
Drosophila melanogaster|Rep: Enhancer of split complex
m5 protein - Drosophila melanogaster (Fruit fly)
Length = 178
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/88 (34%), Positives = 51/88 (57%)
Frame = +1
Query: 118 VSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXX 297
VS+T Y KV P+LER RRAR+N+CLD L + +V+ Q + + +++KA++LE +
Sbjct: 12 VSKTQHYLKVKKPLLERQRRARMNKCLDTL-KTLVAEFQGDDA-ILRMDKAEMLEAALVF 69
Query: 298 XXXXXXXXXXXXNPTVDVDRFRAGFTHA 381
+P + +D F+ G+ +A
Sbjct: 70 MRKQVVKQQAPVSP-LPMDSFKNGYMNA 96
>UniRef50_Q4H3P1 Cluster: Transcription factor protein; n=1; Ciona
intestinalis|Rep: Transcription factor protein - Ciona
intestinalis (Transparent sea squirt)
Length = 258
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 9/125 (7%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXX--- 309
RK P++E+ RR RIN+CL++L ++++A+ +E KLEKADILE+TV
Sbjct: 14 RKTNKPIMEKKRRERINKCLEDLKSIVLTAV-AEESRPNKLEKADILEMTVRYLKSLQQG 72
Query: 310 --XXXXXXXXNPTVDVDRFRAGFTHAAXEVSRC----LASIPGVDVRLGTQLMTHLGHRL 471
+ T D D + E S+C + + V + TQ + HL +
Sbjct: 73 KPIDAGILSLSRTSDYDDSDDDTKSSMTEYSQCDVTTMLNRSDVPLHFRTQFLGHLADKH 132
Query: 472 NEMQR 486
N ++R
Sbjct: 133 NPVER 137
>UniRef50_UPI0000D563AB Cluster: PREDICTED: similar to CG10446-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG10446-PA - Tribolium castaneum
Length = 232
Score = 54.0 bits (124), Expect = 3e-06
Identities = 38/124 (30%), Positives = 62/124 (50%), Gaps = 5/124 (4%)
Frame = +1
Query: 124 RTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXX 303
R + R+ P++E+ RRARIN+ L L L++ + +++ KLEKADILELTV
Sbjct: 7 RASEPRRANKPLMEKRRRARINQSLAALKTLILDSAKADNTKHSKLEKADILELTVRHFQ 66
Query: 304 XXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCL-----ASIPGVDVRLGTQLMTHLGHR 468
V +++AG+ EV R L ++ VD + +L+ HL +
Sbjct: 67 RHRSLDIK------GVHQYKAGYADCVREVQRYLDTPDAQTMTVVDAGVRQRLLRHLDNC 120
Query: 469 LNEM 480
+ E+
Sbjct: 121 VAEV 124
>UniRef50_UPI0000E48019 Cluster: PREDICTED: similar to
hairy/enhancer of split; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to hairy/enhancer of
split - Strongylocentrotus purpuratus
Length = 383
Score = 53.2 bits (122), Expect = 5e-06
Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
Frame = +1
Query: 115 PVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV- 291
P + + + P +E+ RRARIN L +L L++ AL KLEKADILE+TV
Sbjct: 23 PTDDQHPPSRSLKPQMEKRRRARINDSLLQLKNLVLDALNKNNPRHSKLEKADILEMTVR 82
Query: 292 --XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCL 405
N ++ +++ G+ EVSR L
Sbjct: 83 YLRSIHRQQLSGIGSHNEQANIAQYQTGYAECMREVSRYL 122
>UniRef50_Q0P454 Cluster: Zgc:153398; n=6; Clupeocephala|Rep:
Zgc:153398 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 172
Score = 53.2 bits (122), Expect = 5e-06
Identities = 26/53 (49%), Positives = 34/53 (64%)
Frame = +1
Query: 133 QYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
+ RK + P+LE+ RRARIN LD L L++ + KLEKADILE+TV
Sbjct: 7 ELRKTLKPLLEKKRRARINDSLDRLKALILPLTGKDNCRYSKLEKADILEMTV 59
>UniRef50_A7RYX3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 270
Score = 53.2 bits (122), Expect = 5e-06
Identities = 26/51 (50%), Positives = 35/51 (68%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
R++M P+ ER RR RIN L EL L++SAL + ++EKADILE+TV
Sbjct: 23 RRIMKPITERLRRERINSSLKELKFLVLSALGQDVSRYSRMEKADILEMTV 73
>UniRef50_UPI00015B46B7 Cluster: PREDICTED: similar to GA10322-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10322-PA - Nasonia vitripennis
Length = 715
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/84 (39%), Positives = 46/84 (54%)
Frame = +1
Query: 154 PMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXXXXXXX 333
P++E+ RRARIN+ L L L++ + + E KLEKADILELTV
Sbjct: 331 PLMEKRRRARINQSLAALKALILDSARLENTKHSKLEKADILELTV----RHLQRQRSLA 386
Query: 334 NPTVDVDRFRAGFTHAAXEVSRCL 405
P + R++AG+ + EVSR L
Sbjct: 387 QP--GLSRYKAGYQDCSREVSRYL 408
>UniRef50_UPI0000F1EAFE Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 195
Score = 52.8 bits (121), Expect = 7e-06
Identities = 24/54 (44%), Positives = 36/54 (66%)
Frame = +1
Query: 130 YQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
++ RK + P++E+ RRARIN L+ L L++ + + KLEKADILE+TV
Sbjct: 27 HELRKTLKPLMEKRRRARINDSLNHLKTLILPLVGKDASRYSKLEKADILEMTV 80
>UniRef50_Q6YID3 Cluster: Hairy and enhancer of split; n=1;
Helobdella robusta|Rep: Hairy and enhancer of split -
Helobdella robusta (Leech)
Length = 435
Score = 52.4 bits (120), Expect = 9e-06
Identities = 26/58 (44%), Positives = 37/58 (63%)
Frame = +1
Query: 118 VSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
VSR Q RK+ P++E+ RR RIN LD+L L++ A + ++EKADILE+ V
Sbjct: 5 VSRD-QLRKIKKPIIEKKRRERINESLDQLKNLVLEATNKDASMYNRMEKADILEMAV 61
>UniRef50_A3KQ57 Cluster: Hairy and enhancer of split related-7;
n=3; Danio rerio|Rep: Hairy and enhancer of split
related-7 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 206
Score = 52.0 bits (119), Expect = 1e-05
Identities = 32/109 (29%), Positives = 51/109 (46%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK++ P +ER RR R+NR L+ L L++ + N +LEKA+ILE TV
Sbjct: 14 RKLLKPQVERRRRERMNRSLENLKLLLLQGPEHNQPNQRRLEKAEILEYTVLFLQKANKA 73
Query: 319 XXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGH 465
+ +F GF+ + +R L G++ + + L L H
Sbjct: 74 SKEEEGE--EKSQFMEGFSSCLQKAARFLLEEGGLEGSVTSMLCQRLAH 120
>UniRef50_Q9VJ16 Cluster: CG10446-PA; n=4; Diptera|Rep: CG10446-PA -
Drosophila melanogaster (Fruit fly)
Length = 507
Score = 51.6 bits (118), Expect = 2e-05
Identities = 39/98 (39%), Positives = 55/98 (56%), Gaps = 7/98 (7%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMV------SALQSEG-XNVXKLEKADILELTVXX 297
++ P++E+ RRARIN+ L L L++ +A EG KLEKADILELTV
Sbjct: 51 KRTNKPLMEKRRRARINQSLAILKALILESTKTQNAKNGEGQAKHTKLEKADILELTV-- 108
Query: 298 XXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLAS 411
+PT V+++RAG+T A EV+R LA+
Sbjct: 109 --RHFQRHRNLDDPT--VNKYRAGYTDCAREVARYLAT 142
>UniRef50_A7RYX2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 233
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/107 (29%), Positives = 50/107 (46%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK P++E+ RR RIN L+E+ L++ +L + K+EKADILE+TV
Sbjct: 24 RKTKKPLMEKLRRDRINNSLNEMKLLVLESLNKDVSRYSKMEKADILEMTV-KFLKEVNR 82
Query: 319 XXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
N ++AG+ EV +++ L + THL
Sbjct: 83 QDSATNGAQSWSDYKAGYNRRGVEVMPNISTTNTPTGDLTGKFYTHL 129
>UniRef50_Q4RKD6 Cluster: Chromosome 21 SCAF15029, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 21
SCAF15029, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 374
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/105 (34%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Frame = +1
Query: 157 MLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV--XXXXXXXXXXXXX 330
++E+ RR RIN CL EL L+ SA + +G KLEKA+IL++TV
Sbjct: 109 IIEKRRRDRINNCLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHAAGGKGYF 166
Query: 331 XNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVR--LGTQLMTHL 459
+ +D GF E +R L+ I G+D L +L++HL
Sbjct: 167 DAHALAMDYRGLGFRECLAETARYLSIIEGLDGADPLRLRLVSHL 211
>UniRef50_Q7Q509 Cluster: ENSANGP00000020858; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020858 - Anopheles gambiae
str. PEST
Length = 202
Score = 50.8 bits (116), Expect = 3e-05
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 31/157 (19%)
Frame = +1
Query: 112 QPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEG-------------XNV 252
+PV R+ R+ P++E+ RRARIN CL+EL L++ A++ + NV
Sbjct: 27 EPVKRSSDNRRSNKPIMEKRRRARINNCLNELKTLILDAMKKDSFSGSFVAQIALTIINV 86
Query: 253 XKL---------------EKADILELTV---XXXXXXXXXXXXXXNPTVDVDRFRAGFTH 378
L EKADILE+TV +P+V +++F+AGF
Sbjct: 87 SPLFLLSSTSQPARHSKLEKADILEMTVKHLENLQRQQTAMSQATDPSV-MNKFKAGFNE 145
Query: 379 AAXEVSRCLASIPGVDVRLGTQLMTHLGHRLNEMQRA 489
A EV R P ++ + +L+ HL + +N + ++
Sbjct: 146 CAQEVGR----FPELEPHVKRRLLQHLNNCINGVNKS 178
>UniRef50_Q96HZ4 Cluster: Transcription cofactor HES-6; n=18;
cellular organisms|Rep: Transcription cofactor HES-6 -
Homo sapiens (Human)
Length = 224
Score = 50.8 bits (116), Expect = 3e-05
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 2/109 (1%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXX 318
RK P++E+ RRARIN L EL L+ A KLE A++LELTV
Sbjct: 26 RKARKPLVEKKRRARINESLQELRLLLAGAEVQ-----AKLENAEVLELTVRRVQGVLRG 80
Query: 319 XXXXXN--PTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL 459
+RF AG+ EV +++ +D + +L+ HL
Sbjct: 81 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 129
>UniRef50_Q9YI65 Cluster: Basic-helix-loop-helix transcription
factor hairy2b; n=2; Xenopus|Rep: Basic-helix-loop-helix
transcription factor hairy2b - Xenopus laevis (African
clawed frog)
Length = 274
Score = 50.4 bits (115), Expect = 4e-05
Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Frame = +1
Query: 217 MVSALQSEGXNVXKLEKADILELTVXXXXXXXX---XXXXXXNPTVDVDRFRAGFTHAAX 387
M+ + + KLEKADILE+TV +P+V + ++RAGF
Sbjct: 35 MIPCISPQSSRHSKLEKADILEMTVKHLRNLQRVQMTAALTSDPSV-LGKYRAGFNECTN 93
Query: 388 EVSRCLASIPGVDVRLGTQLMTHLGHRLNEM 480
EV+R L++ GV+ + T+L+ HL L ++
Sbjct: 94 EVTRFLSTCEGVNTEVRTRLLGHLSSCLGQI 124
>UniRef50_UPI00000181D8 Cluster: Homolog of Brachydanio rerio "Hairy
and enhancer of split 6.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Hairy and enhancer of
split 6. - Takifugu rubripes
Length = 186
Score = 49.6 bits (113), Expect = 6e-05
Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 5/116 (4%)
Frame = +1
Query: 154 PMLERXRRARINRCLDELXELMVSA-LQSEGXNVXKLEKADILELTVXXXXXXXXXXX-- 324
P++E+ RRARIN+ L+EL L+ LQS KLE A++L +TV
Sbjct: 5 PLVEKKRRARINKSLEELRLLVAEPDLQS------KLENAELLAMTVKRVENILQDPTPD 58
Query: 325 XXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHL--GHRLNEMQR 486
+ +RF AG+ +V +++ PGVD +L+ HL LN+ +R
Sbjct: 59 AEASSREACERFTAGYIQCMHDVHTFVSTCPGVDQTFAAELLHHLMESMPLNDQER 114
>UniRef50_Q8UW74 Cluster: HES-related 1A; n=4; Xenopus|Rep:
HES-related 1A - Xenopus laevis (African clawed frog)
Length = 180
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/117 (29%), Positives = 57/117 (48%)
Frame = +1
Query: 106 GPQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILEL 285
G V +RK++ P++E+ RR RIN L++L + L+SE K+EKA+ILE
Sbjct: 3 GTSEVKPMETHRKLLKPLVEKRRRERINNSLEKLRIFLFQTLKSEKLKNPKVEKAEILEC 62
Query: 286 TVXXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTH 456
TV VD + +++GF H + S P ++ + +L++H
Sbjct: 63 TV--QFLQSRKLLPLDREAVDKE-YQSGFQHCLETTLHFMNSKPDMN-GVTKELLSH 115
>UniRef50_Q7T3J0 Cluster: Hairy and enhancer of split 5; n=3; Danio
rerio|Rep: Hairy and enhancer of split 5 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 149
Score = 49.6 bits (113), Expect = 6e-05
Identities = 23/50 (46%), Positives = 34/50 (68%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
K+ P++E+ RR RIN C+++L ++ Q + N KLEKADILE+TV
Sbjct: 19 KLRKPVVEKMRRDRINNCIEQLKSMLEKEFQQQDPN-AKLEKADILEMTV 67
>UniRef50_A7S152 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 170
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/55 (54%), Positives = 38/55 (69%), Gaps = 5/55 (9%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSAL-----QSEGXNVXKLEKADILELTV 291
K P+LER RRARIN L+EL L++S+L Q+E N K+EKA+ILELTV
Sbjct: 20 KSSKPLLERQRRARINHSLNELKTLVLSSLYQNCPQAE-QNCEKMEKAEILELTV 73
>UniRef50_Q4QRL6 Cluster: Hairy-related 12; n=2; Danio rerio|Rep:
Hairy-related 12 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 155
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/50 (48%), Positives = 33/50 (66%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
K+ P++E+ RR RIN C+D+L L+ S + KLEKADILE+TV
Sbjct: 23 KLRKPIVEKMRRDRINTCIDQLKSLLEKEFHSHDPS-TKLEKADILEMTV 71
>UniRef50_Q9W7B6 Cluster: BHLH-WRPW transcription factor ESR-5; n=2;
Xenopus laevis|Rep: BHLH-WRPW transcription factor ESR-5
- Xenopus laevis (African clawed frog)
Length = 203
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/57 (42%), Positives = 36/57 (63%)
Frame = +1
Query: 121 SRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
S T+ RK++ P++E+ RR RINR L E+ L+ ++ K+EKA+ILEL V
Sbjct: 7 SDTFPSRKILKPVVEKQRRDRINRSLGEMRILLFQLTGNQKLQNPKMEKAEILELAV 63
>UniRef50_Q4S814 Cluster: Chromosome 9 SCAF14710, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 9
SCAF14710, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 182
Score = 48.0 bits (109), Expect = 2e-04
Identities = 23/46 (50%), Positives = 32/46 (69%)
Frame = +1
Query: 154 PMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
P++E+ RR RIN C+D+L ++ Q + N KLEKADILE+TV
Sbjct: 53 PVVEKMRRDRINSCIDQLKVILEKEFQKQEPN-SKLEKADILEMTV 97
>UniRef50_UPI00015B47F2 Cluster: PREDICTED: similar to RT01017p;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
RT01017p - Nasonia vitripennis
Length = 306
Score = 47.2 bits (107), Expect = 3e-04
Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 5/112 (4%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV---XXXXXX 309
RK M+E+ RR RIN L EL L+ +A + + KLEKA+IL+LTV
Sbjct: 130 RKRRRGMIEKKRRDRINASLGELRRLVPAAARDP--HSGKLEKAEILQLTVEHLRTLRNK 187
Query: 310 XXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVR--LGTQLMTHL 459
+ + +D G+ EV R L ++ G+D R L +L++HL
Sbjct: 188 VLRDLGYDSTKLAMDYHAVGWGECVAEVGRYLVTMEGLDERDPLRLRLLSHL 239
>UniRef50_Q6QB00 Cluster: Her/Hey-like protein; n=2;
Clupeocephala|Rep: Her/Hey-like protein - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 270
Score = 46.8 bits (106), Expect = 5e-04
Identities = 25/49 (51%), Positives = 34/49 (69%)
Frame = +1
Query: 145 VMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
V ++E+ RR RINRCL+EL + + AL + N KLEKA+ILE+TV
Sbjct: 62 VSHKVIEKRRRDRINRCLNELGKTVPMALAKQ--NSGKLEKAEILEMTV 108
>UniRef50_Q6V6Y9 Cluster: Hairy H protein; n=2; Coelomata|Rep: Hairy
H protein - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 66
Score = 46.8 bits (106), Expect = 5e-04
Identities = 25/57 (43%), Positives = 37/57 (64%), Gaps = 2/57 (3%)
Frame = +1
Query: 121 SRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSE--GXNVXKLEKADILEL 285
S +Q RK P++E+ RRARIN L+EL L++ ++ + + KLEKADILE+
Sbjct: 10 SSPHQGRKSSKPLMEKRRRARINSSLNELKNLILGTVKDDINAPHHSKLEKADILEI 66
>UniRef50_Q9BYE0 Cluster: Transcription factor HES-7; n=11;
Theria|Rep: Transcription factor HES-7 - Homo sapiens
(Human)
Length = 225
Score = 46.4 bits (105), Expect = 6e-04
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
K++ P++E+ RR RINR L+EL L++ + + KLEKA+ILE V
Sbjct: 14 KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV 63
>UniRef50_Q2TP33 Cluster: Her5; n=1; Oryzias latipes|Rep: Her5 -
Oryzias latipes (Medaka fish) (Japanese ricefish)
Length = 192
Score = 46.0 bits (104), Expect = 8e-04
Identities = 24/51 (47%), Positives = 32/51 (62%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
R++ P++ER RR RIN L+ L LMV Q+E K+EKA+ILE V
Sbjct: 16 RRMSKPLMERRRRERINHSLETLRLLMVKHTQNEKLKNPKVEKAEILESVV 66
>UniRef50_A7SMU2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 481
Score = 46.0 bits (104), Expect = 8e-04
Identities = 25/45 (55%), Positives = 32/45 (71%)
Frame = +1
Query: 157 MLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
++E+ RR RIN CL EL +L+ SA Q+ KLEKA+ILELTV
Sbjct: 52 VIEKRRRDRINSCLSELAQLIPSA-QNGKQGSGKLEKAEILELTV 95
>UniRef50_Q5TYJ1 Cluster: ENSANGP00000029214; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000029214 - Anopheles gambiae
str. PEST
Length = 141
Score = 33.5 bits (73), Expect(2) = 8e-04
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Frame = +1
Query: 256 KLEKADILELTV---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVD 426
KLEKADIL+LTV +PTV ++F G+ E+ + S+ VD
Sbjct: 68 KLEKADILDLTVKHLQDVERRRLNVAMAVDPTVP-EKFANGYRECIDEIGKYFDSLGSVD 126
Query: 427 VRLGTQLMTHL 459
L ++ HL
Sbjct: 127 EGLKARVRKHL 137
Score = 31.9 bits (69), Expect(2) = 8e-04
Identities = 12/29 (41%), Positives = 22/29 (75%)
Frame = +1
Query: 154 PMLERXRRARINRCLDELXELMVSALQSE 240
P++E+ RRARIN L++L L++ A++ +
Sbjct: 5 PIMEKKRRARINNYLNDLKSLLLDAMKKD 33
>UniRef50_Q4W593 Cluster: ESR4; n=3; Xenopus|Rep: ESR4 - Xenopus
tropicalis (Western clawed frog) (Silurana tropicalis)
Length = 243
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/51 (43%), Positives = 33/51 (64%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
+++M P++E+ RR RIN+ L+ L L++ A E K EKADIL+ TV
Sbjct: 25 KRLMKPVIEKRRRDRINQSLEHLRTLLLEATHDETLKNPKAEKADILKKTV 75
>UniRef50_Q53U32 Cluster: Enhancer of split related protein 3/7b;
n=3; Xenopus|Rep: Enhancer of split related protein 3/7b
- Xenopus laevis (African clawed frog)
Length = 159
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/50 (46%), Positives = 34/50 (68%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
K+ P++E+ RR RIN +++L L+ + + NV KLEKADILE+TV
Sbjct: 20 KLRKPVVEKMRRDRINSSIEQLKVLLENVFHQQEPNV-KLEKADILEMTV 68
>UniRef50_Q2TP34 Cluster: Her1-11; n=1; Oryzias latipes|Rep: Her1-11
- Oryzias latipes (Medaka fish) (Japanese ricefish)
Length = 269
Score = 44.8 bits (101), Expect = 0.002
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVX-----XXX 303
++++ P++E+ RR RIN+ L EL L+++ + KLEKA+IL+L V
Sbjct: 15 KRILKPVVEKKRRDRINQSLAELRSLLLNVTSDPRLHNPKLEKAEILDLAVEYLKKWTDR 74
Query: 304 XXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDVRLGTQLMTHLGHRLNEMQ 483
P + + AGF H +VS+ + + V T+LM L H +Q
Sbjct: 75 KNARDAESSAPPLLSTE--TAGFQH---QVSQLTSFMHKVTPAQRTRLMETLRHHAESLQ 129
>UniRef50_A3KQ56 Cluster: Hairy-related 1; n=3; Danio rerio|Rep:
Hairy-related 1 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 328
Score = 43.6 bits (98), Expect = 0.004
Identities = 21/51 (41%), Positives = 33/51 (64%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
++++ P++E+ RR RIN+ L+EL L++ KLEKA+ILEL V
Sbjct: 13 KRILKPVIEKKRRDRINQRLEELRTLLLDNTLDSRLQNPKLEKAEILELAV 63
>UniRef50_O16853 Cluster: Lin-22; n=2; Caenorhabditis|Rep: Lin-22 -
Caenorhabditis elegans
Length = 173
Score = 43.6 bits (98), Expect = 0.004
Identities = 19/46 (41%), Positives = 29/46 (63%)
Frame = +1
Query: 154 PMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
P++E+ RRARIN+ L +L ++++ K EKADILE+ V
Sbjct: 27 PLMEKKRRARINKSLSQLKQILIQDEHKNSIQHSKWEKADILEMAV 72
>UniRef50_UPI0000D5710A Cluster: PREDICTED: similar to CG10446-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG10446-PA - Tribolium castaneum
Length = 177
Score = 43.2 bits (97), Expect = 0.006
Identities = 24/58 (41%), Positives = 36/58 (62%), Gaps = 8/58 (13%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMV--------SALQSEGXNVXKLEKADILELTV 291
+V P++E+ RRARIN L+ L ++++ S+ + G KLEKADILE+TV
Sbjct: 47 RVRKPLMEKKRRARINDSLEALKQILLDSKTTLKESSGKKSGQRTAKLEKADILEMTV 104
>UniRef50_UPI00015A7FE8 Cluster: hairy-related 1; n=3;
Euteleostomi|Rep: hairy-related 1 - Danio rerio
Length = 63
Score = 43.2 bits (97), Expect = 0.006
Identities = 21/51 (41%), Positives = 33/51 (64%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
++++ P++E+ RR RIN+ L+EL L++ KLEKA+ILEL V
Sbjct: 13 QRILKPVIEKKRRDRINQRLEELRTLLLDNTLDSRLQNPKLEKAEILELAV 63
>UniRef50_Q5D212 Cluster: Hairy and enhancer of split 5; n=10;
Tetrapoda|Rep: Hairy and enhancer of split 5 - Gallus
gallus (Chicken)
Length = 157
Score = 41.9 bits (94), Expect = 0.013
Identities = 22/50 (44%), Positives = 32/50 (64%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
++ P++E+ RR RIN +++L L+ Q N KLEKADILE+TV
Sbjct: 18 RLRKPIVEKLRRDRINSSIEQLKLLLEKEFQRHQPN-SKLEKADILEMTV 66
>UniRef50_Q693N2 Cluster: Hairy; n=1; Clogmia albipunctata|Rep:
Hairy - Clogmia albipunctata (Mothmidge)
Length = 316
Score = 41.9 bits (94), Expect = 0.013
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 3/85 (3%)
Frame = +1
Query: 256 KLEKADILELTVXXXXXXX---XXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVD 426
KLEKADILE TV +P V +++F+AGFT A EV R G+D
Sbjct: 7 KLEKADILEKTVKHLQDLQRQQSVLSQASDPGV-INKFKAGFTECANEVGR----FGGID 61
Query: 427 VRLGTQLMTHLGHRLNEMQRAXAGT 501
+ +L+ HL + LN ++ +G+
Sbjct: 62 PIVKRRLLQHLSNCLNGVRTDLSGS 86
>UniRef50_Q504H7 Cluster: Her5 protein; n=3; Danio rerio|Rep: Her5
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 225
Score = 41.5 bits (93), Expect = 0.017
Identities = 21/51 (41%), Positives = 32/51 (62%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
R+V P++E+ RR RIN+ L+ L L++ +E K+EKA+ILE V
Sbjct: 27 RRVPKPLMEKRRRDRINQSLETLRMLLLENTNNEKLKNPKVEKAEILESVV 77
>UniRef50_Q96HZ4-2 Cluster: Isoform 2 of Q96HZ4 ; n=2;
Catarrhini|Rep: Isoform 2 of Q96HZ4 - Homo sapiens
(Human)
Length = 219
Score = 41.1 bits (92), Expect = 0.022
Identities = 24/51 (47%), Positives = 30/51 (58%)
Frame = +1
Query: 139 RKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
RK P++E+ RRARIN L EL L+ A KLE A++LELTV
Sbjct: 26 RKARKPLVEKKRRARINESLQELRLLLAGAEVQ-----AKLENAEVLELTV 71
>UniRef50_Q90Z13 Cluster: Enhancer of split related 2; n=2;
Xenopus|Rep: Enhancer of split related 2 - Xenopus
laevis (African clawed frog)
Length = 183
Score = 40.7 bits (91), Expect = 0.030
Identities = 24/55 (43%), Positives = 32/55 (58%)
Frame = +1
Query: 127 TYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
T Q K+ PM+E+ RR RIN +++L L+ Q + K EKADILEL V
Sbjct: 40 TKQKTKIRKPMVEKMRRDRINSSINQLRNLLEQEFQLLQPD-SKPEKADILELAV 93
>UniRef50_Q6W4T8 Cluster: Her11; n=3; Danio rerio|Rep: Her11 - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 274
Score = 40.7 bits (91), Expect = 0.030
Identities = 21/58 (36%), Positives = 34/58 (58%)
Frame = +1
Query: 118 VSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
+++T ++ + P++E+ RR RIN LD L +L+ KLEKA+IL+L V
Sbjct: 9 MTKTEGIKRRLKPVIEKKRRDRINHNLDALRDLLFKNTADTRLQNPKLEKAEILDLAV 66
>UniRef50_A7S155 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 184
Score = 40.7 bits (91), Expect = 0.030
Identities = 25/56 (44%), Positives = 35/56 (62%), Gaps = 6/56 (10%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNV------XKLEKADILELTV 291
K +LER RRARIN+ L EL L++S+L + V +L+KA+IL+LTV
Sbjct: 15 KASKHILERQRRARINQSLAELKNLVLSSLYHDNPEVYMDKSRERLDKAEILDLTV 70
>UniRef50_Q53U31 Cluster: Enhancer of split related protein 1b; n=1;
Xenopus laevis|Rep: Enhancer of split related protein 1b
- Xenopus laevis (African clawed frog)
Length = 154
Score = 40.3 bits (90), Expect = 0.039
Identities = 22/50 (44%), Positives = 31/50 (62%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
K+ P++E+ RR RIN +++L L+ + NV KLEKADILE V
Sbjct: 18 KLRKPIVEKMRRDRINNSIEQLKLLLGKEFHEQEPNV-KLEKADILEKAV 66
>UniRef50_Q4S832 Cluster: Chromosome 9 SCAF14710, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 9 SCAF14710, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 89
Score = 39.5 bits (88), Expect = 0.068
Identities = 17/32 (53%), Positives = 23/32 (71%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQS 237
KV P++E+ RRARIN+CLD+L L+ S S
Sbjct: 1 KVSKPLMEKKRRARINKCLDQLKSLLESYYSS 32
>UniRef50_A6NFD8 Cluster: Uncharacterized protein ENSP00000343464;
n=10; Theria|Rep: Uncharacterized protein
ENSP00000343464 - Homo sapiens (Human)
Length = 327
Score = 33.5 bits (73), Expect(2) = 0.098
Identities = 15/33 (45%), Positives = 22/33 (66%)
Frame = +1
Query: 145 VMXPMLERXRRARINRCLDELXELMVSALQSEG 243
V ++E+ RR RINRCL+EL + + AL +G
Sbjct: 57 VSHKVIEKRRRDRINRCLNELGKTVPMALAKQG 89
Score = 24.6 bits (51), Expect(2) = 0.098
Identities = 14/21 (66%), Positives = 16/21 (76%)
Frame = +1
Query: 229 LQSEGXNVXKLEKADILELTV 291
LQS G KLEKA+ILE+TV
Sbjct: 128 LQSSG----KLEKAEILEMTV 144
>UniRef50_Q9PTN9 Cluster: Enhancer of split related epidermal
protein-6; n=2; Xenopus|Rep: Enhancer of split related
epidermal protein-6 - Xenopus laevis (African clawed
frog)
Length = 144
Score = 38.3 bits (85), Expect = 0.16
Identities = 20/46 (43%), Positives = 30/46 (65%)
Frame = +1
Query: 154 PMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
P++E+ RR RIN +++L L+ Q+ + KLEKADILE+ V
Sbjct: 5 PVIEKMRRDRINNSIEQLRILLERNFQTHHPH-SKLEKADILEMAV 49
>UniRef50_Q4V986 Cluster: Her4.2 protein; n=8; Danio rerio|Rep:
Her4.2 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 152
Score = 37.9 bits (84), Expect = 0.21
Identities = 19/50 (38%), Positives = 31/50 (62%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
K+ PM+E+ RR RIN +++L L+ + + + EKADILE+T+
Sbjct: 19 KLRKPMVEKIRRERINSSIEKLKTLLAQEFVKQQPD-SRQEKADILEMTL 67
>UniRef50_UPI0000360D97 Cluster: Transcription factor HES-5 (Hairy
and enhancer of split 5).; n=2; Takifugu rubripes|Rep:
Transcription factor HES-5 (Hairy and enhancer of split
5). - Takifugu rubripes
Length = 147
Score = 37.5 bits (83), Expect = 0.28
Identities = 18/46 (39%), Positives = 30/46 (65%)
Frame = +1
Query: 154 PMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
P++E+ RR RIN +++L L+ + + K+EKAD+LE+TV
Sbjct: 13 PLVEKLRRERINSSIEQLKSLLGPEFFKQQPD-SKMEKADVLEMTV 57
>UniRef50_Q5TA89 Cluster: Transcription factor HES-5; n=11;
Amniota|Rep: Transcription factor HES-5 - Homo sapiens
(Human)
Length = 166
Score = 37.5 bits (83), Expect = 0.28
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
++ P++E+ RR RIN +++L L+ N KLEKADILE+ V
Sbjct: 18 RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAV 66
>UniRef50_Q5TGS1 Cluster: Transcription factor HES-3; n=11;
Eutheria|Rep: Transcription factor HES-3 - Homo sapiens
(Human)
Length = 186
Score = 37.5 bits (83), Expect = 0.28
Identities = 22/44 (50%), Positives = 28/44 (63%)
Frame = +1
Query: 160 LERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
+E+ RRARIN L++L L+ S KLEKADILEL+V
Sbjct: 1 MEKKRRARINVSLEQLKSLLEKHY-SHQIRKRKLEKADILELSV 43
>UniRef50_Q90464 Cluster: HER-2 protein; n=1; Danio rerio|Rep: HER-2
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 108
Score = 37.1 bits (82), Expect = 0.36
Identities = 22/80 (27%), Positives = 39/80 (48%)
Frame = +1
Query: 172 RRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTVXXXXXXXXXXXXXXNPTVDV 351
RR RIN+C+++L L+ + +++ KLEKADILE+ V +
Sbjct: 2 RRDRINKCIEQLKILLKTEIKA-SQPCSKLEKADILEMAVIYLKNTADAHARSYS-EAHA 59
Query: 352 DRFRAGFTHAAXEVSRCLAS 411
+ G++ E +R L++
Sbjct: 60 QSYADGYSRCIEETARFLSA 79
>UniRef50_Q1L7T5 Cluster: Her4; n=5; Percomorpha|Rep: Her4 - Oryzias
latipes (Medaka fish) (Japanese ricefish)
Length = 166
Score = 37.1 bits (82), Expect = 0.36
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +1
Query: 142 KVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
K+ PM+E+ RR RIN +++L L+ + + K EKADILE+ V
Sbjct: 19 KLRKPMVEKLRRDRINTSIEQLKSLLSPEFLRQQPD-SKQEKADILEMAV 67
>UniRef50_Q16SR7 Cluster: Class b basic helix-loop-helix protein;
n=2; Culicidae|Rep: Class b basic helix-loop-helix
protein - Aedes aegypti (Yellowfever mosquito)
Length = 507
Score = 37.1 bits (82), Expect = 0.36
Identities = 29/139 (20%), Positives = 60/139 (43%), Gaps = 3/139 (2%)
Frame = +1
Query: 97 AEDGPQPVSRTYQYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADI 276
A+ P +T + + ++E+ RR R+N CL +L L+ +G ++EK +I
Sbjct: 30 ADFAPGRRGKTSRQDPLSHRIIEKRRRDRMNSCLADLSRLIPQQYMRKGRG--RVEKTEI 87
Query: 277 LELTVXXXXXXXXXXXXXXNPTVDVDRFRAGFTHAAXEVSRCLASIPGVDV--RLGTQLM 450
+E+ + N +++R G+ E ++ + G ++ R+ L
Sbjct: 88 IEMAIRHLKNLQNQECARENSC--SEQYRVGYHDCLTEAAKFMLRERGEEMCYRMVAHLK 145
Query: 451 THLGHRL-NEMQRAXAGTE 504
H + EM ++ G+E
Sbjct: 146 EHCNEIMKGEMMKSRCGSE 164
>UniRef50_Q693M9 Cluster: Hairy; n=1; Coboldia fuscipes|Rep: Hairy -
Coboldia fuscipes
Length = 253
Score = 35.1 bits (77), Expect = 1.5
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 214 LMVSALQSEGXNVXKLEKADILELTV---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAA 384
L++ A + + KLEKADILE TV NP V +++F+AG+
Sbjct: 2 LILDATKKDPARHSKLEKADILEKTVKYLQDLQRQQSIISQAANPKV-LNKFKAGYMECV 60
Query: 385 XEVSRCLASIPGVDVRLGTQLMTHL 459
+V R PG++ + L+ HL
Sbjct: 61 NQVER----FPGLEPDIRRCLVQHL 81
>UniRef50_Q5KHD0 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 641
Score = 34.7 bits (76), Expect = 1.9
Identities = 22/53 (41%), Positives = 30/53 (56%)
Frame = +1
Query: 133 QYRKVMXPMLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
Q RKV ++ER RR +IN L+EL MV +L G + K ++LE TV
Sbjct: 130 QLRKVNHSLIERRRREKINAALNELRR-MVPSLGENGGKGGEF-KLEVLEKTV 180
>UniRef50_Q9VGZ5 Cluster: CG17100-PA; n=4; Sophophora|Rep:
CG17100-PA - Drosophila melanogaster (Fruit fly)
Length = 698
Score = 33.9 bits (74), Expect = 3.4
Identities = 15/45 (33%), Positives = 28/45 (62%)
Frame = +1
Query: 157 MLERXRRARINRCLDELXELMVSALQSEGXNVXKLEKADILELTV 291
++E+ RR R+N CL +L L+ Q +G ++EK +I+E+ +
Sbjct: 69 IIEKRRRDRMNSCLADLSRLIPPQYQRKGRG--RIEKTEIIEMAI 111
>UniRef50_A7IHQ2 Cluster: SMC domain protein; n=1; Xanthobacter
autotrophicus Py2|Rep: SMC domain protein - Xanthobacter
sp. (strain Py2)
Length = 880
Score = 33.5 bits (73), Expect = 4.5
Identities = 24/74 (32%), Positives = 29/74 (39%)
Frame = -3
Query: 225 ADHQLXEFVEAAVDASAPLALKHRXHHFAILISARDWLRTVFRDLNTRSRMTCXMYVCRE 46
ADH + A AL+H I ARD RT RD N R RM + E
Sbjct: 320 ADHAEAMARARTAEQDAAAALEHARTELRIAEDARDTARTE-RDANERRRMLVAAFARLE 378
Query: 45 *ERTFAKSVEARES 4
A + ARE+
Sbjct: 379 RAEALAGDIRAREA 392
>UniRef50_Q4WNJ9 Cluster: Peptide alpha-N-acetyltransferase Nat2,
putative; n=2; Trichocomaceae|Rep: Peptide
alpha-N-acetyltransferase Nat2, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 253
Score = 32.7 bits (71), Expect = 7.8
Identities = 14/24 (58%), Positives = 16/24 (66%)
Frame = -2
Query: 586 RPEEMGSRNQTMKKQSREQGWEGL 515
RP E GS +Q +KK SRE GW L
Sbjct: 104 RPAESGSLSQRLKKLSREYGWAAL 127
>UniRef50_A4REQ7 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 651
Score = 32.7 bits (71), Expect = 7.8
Identities = 15/36 (41%), Positives = 22/36 (61%)
Frame = -2
Query: 496 QRLLAAFRSVCARGGSLVECPTSRPHQELKPDSGKL 389
+ +L R V A+ GS+ + P+SR H E+ DSG L
Sbjct: 510 KEVLGLQRKVLAKSGSISQDPSSRRHAEMSVDSGPL 545
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 563,915,414
Number of Sequences: 1657284
Number of extensions: 9641274
Number of successful extensions: 23370
Number of sequences better than 10.0: 109
Number of HSP's better than 10.0 without gapping: 22747
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 23301
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 48760335122
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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