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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= e96h0031
         (821 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;...   113   5e-24
UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;...   110   4e-23
UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase, putat...    91   2e-17
UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24; Eu...    85   2e-15
UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep: G...    81   3e-14
UniRef50_Q96BZ3 Cluster: HAGHL protein; n=2; Homo sapiens|Rep: H...    79   1e-13
UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase...    79   2e-13
UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrola...    75   2e-12
UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase cytopl...    72   2e-11
UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase, putat...    70   8e-11
UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,...    68   2e-10
UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome sh...    66   8e-10
UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to myofibrill...    66   1e-09
UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome sh...    65   2e-09
UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella ve...    65   2e-09
UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep: Gl...    64   5e-09
UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase, putat...    63   9e-09
UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein;...    62   1e-08
UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20; Ascomy...    62   1e-08
UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2; ...    62   2e-08
UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1; ...    61   4e-08
UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep...    60   5e-08
UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    60   5e-08
UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Re...    60   9e-08
UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25; Euteleos...    60   9e-08
UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;...    59   1e-07
UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein; ...    58   3e-07
UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    56   1e-06
UniRef50_UPI0000E4A799 Cluster: PREDICTED: similar to CG4365-PC,...    55   2e-06
UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep: ...    55   2e-06
UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase, putat...    54   4e-06
UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    53   8e-06
UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily prot...    53   8e-06
UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB; ...    52   2e-05
UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrola...    52   2e-05
UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4; ...    51   3e-05
UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    51   4e-05
UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1; ...    50   5e-05
UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    50   7e-05
UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1; ...    50   7e-05
UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    50   9e-05
UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathion...    49   1e-04
UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily prot...    49   1e-04
UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1, mit...    49   1e-04
UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrola...    49   2e-04
UniRef50_UPI0000DAE586 Cluster: hypothetical protein Rgryl_01000...    48   2e-04
UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyo...    48   3e-04
UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    48   4e-04
UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase, mitoc...    48   4e-04
UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    47   5e-04
UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteri...    47   7e-04
UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase, putat...    47   7e-04
UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3; ...    44   0.005
UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    44   0.006
UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase precur...    44   0.006
UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily hydr...    43   0.008
UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein; ...    43   0.011
UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrola...    43   0.011
UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase precur...    42   0.014
UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    42   0.019
UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3; ...    42   0.019
UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase precur...    40   0.057
UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase, putat...    40   0.057
UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas...    40   0.075
UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    40   0.075
UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1; ...    40   0.099
UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1; Geo...    39   0.17 
UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase, putat...    38   0.23 
UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrola...    38   0.23 
UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein; ...    38   0.30 
UniRef50_UPI00006CD5DA Cluster: TNFR/NGFR cysteine-rich region f...    38   0.40 
UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    38   0.40 
UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;...    38   0.40 
UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily prot...    38   0.40 
UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including glyox...    38   0.40 
UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, who...    38   0.40 
UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of met...    37   0.53 
UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    37   0.53 
UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB; ...    37   0.70 
UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily prot...    36   0.93 
UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1; Roseo...    36   0.93 
UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium c...    36   0.93 
UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    36   1.2  
UniRef50_Q41EG0 Cluster: Beta-lactamase-like:Rhodanese-like; n=4...    36   1.2  
UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    36   1.2  
UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein; ...    36   1.6  
UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein; ...    36   1.6  
UniRef50_Q7X477 Cluster: AhlK; n=12; Proteobacteria|Rep: AhlK - ...    36   1.6  
UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon...    36   1.6  
UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    35   2.1  
UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrola...    35   2.1  
UniRef50_A1HQX4 Cluster: Beta-lactamase domain protein; n=1; The...    35   2.1  
UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1; ...    35   2.1  
UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2...    35   2.8  
UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein; ...    35   2.8  
UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase relate...    35   2.8  
UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase, putat...    34   3.7  
UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase, putat...    34   3.7  
UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrola...    34   3.7  
UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily prot...    34   3.7  
UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein; ...    34   4.9  
UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1; Clo...    34   4.9  
UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2; Bac...    34   4.9  
UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    34   4.9  
UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily prot...    34   4.9  
UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4; Hal...    34   4.9  
UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including glyox...    33   6.5  
UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3; Deltaproteoba...    33   6.5  
UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3; Leptospira...    33   6.5  
UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1; Lenti...    33   6.5  
UniRef50_Q10428 Cluster: Serine/threonine-protein phosphatase 2A...    33   6.5  
UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase, putat...    33   8.6  
UniRef50_Q1ARM7 Cluster: Beta-lactamase-like protein; n=1; Rubro...    33   8.6  
UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1; Alk...    33   8.6  
UniRef50_A1U0H3 Cluster: Beta-lactamase domain protein; n=1; Mar...    33   8.6  

>UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;
           Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Homo
           sapiens (Human)
          Length = 260

 Score =  113 bits (272), Expect = 5e-24
 Identities = 72/186 (38%), Positives = 97/186 (52%), Gaps = 3/186 (1%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M V++LPAL DNYMYL++D  TKEAAIVDPV+P+ V+ A  + GV L            A
Sbjct: 1   MKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHA 60

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVIS 614
           GGNE L+K   GL VYGGDDRIG    K++ + +L+  +        P    G   Y +S
Sbjct: 61  GGNEKLVKLESGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVS 120

Query: 615 *LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH-*MFCGHEYTLA 791
                +     +  GDTLF+ GCG+         C    +      P   ++CGHEYT+ 
Sbjct: 121 KPGGSEPPAVFT--GDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTIN 178

Query: 792 GIXKFA 809
            + KFA
Sbjct: 179 NL-KFA 183



 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 38/74 (51%), Positives = 48/74 (64%)
 Frame = +2

Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
           ALT K+ H +  ++G+LNV+CL TPCHT+GHICYFV+ P       VFTG  TL      
Sbjct: 84  ALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGD-TLFVAGCG 142

Query: 689 GSLKGTADQMYKAL 730
              +GTAD+M KAL
Sbjct: 143 KFYEGTADEMCKAL 156


>UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;
           Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Mus
           musculus (Mouse)
          Length = 260

 Score =  110 bits (265), Expect = 4e-23
 Identities = 72/186 (38%), Positives = 101/186 (54%), Gaps = 3/186 (1%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M V++LPAL DNYMYLI+D+ T+EAAIVDPV+P+ V++A ++  V L            A
Sbjct: 1   MKVELLPALTDNYMYLIIDEDTQEAAIVDPVQPQKVIEAAKKHHVKLTTVLTTHHHWDHA 60

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
           GGNE L+K  PGL VYGGDDRIG    K++ + +L+  +        P    G   I   
Sbjct: 61  GGNEKLVKLEPGLKVYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSG--HICYF 118

Query: 621 LQKKVTIQLSS--PGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH-*MFCGHEYTLA 791
           + K  + + S+   GDTLF+ GCG+              +      P   ++CGHEYT+ 
Sbjct: 119 VSKPGSSEPSAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPDTKVYCGHEYTVN 178

Query: 792 GIXKFA 809
            + KFA
Sbjct: 179 NL-KFA 183



 Score = 83.4 bits (197), Expect = 6e-15
 Identities = 40/74 (54%), Positives = 50/74 (67%)
 Frame = +2

Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
           ALT KV H +  ++G+L+V+CL TPCHT+GHICYFV+ P     S VFTG  TL      
Sbjct: 84  ALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPSAVFTGD-TLFVAGCG 142

Query: 689 GSLKGTADQMYKAL 730
              +GTAD+MYKAL
Sbjct: 143 KFYEGTADEMYKAL 156


>UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase,
           putative, expressed; n=3; Oryza sativa|Rep:
           Hydroxyacylglutathione hydrolase, putative, expressed -
           Oryza sativa subsp. japonica (Rice)
          Length = 258

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 61/181 (33%), Positives = 89/181 (49%), Gaps = 4/181 (2%)
 Frame = +3

Query: 267 VKILPA--LQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           +KI+P   L+DNY YLIVD++TK AA VDPVEP+ VL A  E GV +            A
Sbjct: 1   MKIIPVACLEDNYAYLIVDESTKSAAAVDPVEPEKVLAAAAEVGVRIDCVLTTHHHWDHA 60

Query: 441 GGNEDLIKERPGLIVYGGD-DRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
           GGNE + +  PG+ VYGG  D +     ++     L     +  + LH       ++   
Sbjct: 61  GGNEKMAQSVPGIKVYGGSLDNVKGCTDQVENGTKLSLGKDIEILCLHTPCHTKGHISYY 120

Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL-*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAG 794
           +  K+        GDTLF+ GCG+     A Q+  +      +   P  ++CGHEYT+  
Sbjct: 121 VTSKEEEDPAVFTGDTLFIAGCGRFFEGTAEQMYQSLCVTLGSLPKPTQVYCGHEYTVKN 180

Query: 795 I 797
           +
Sbjct: 181 L 181


>UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24;
           Euteleostomi|Rep: Uncharacterized protein HAGHL - Homo
           sapiens (Human)
          Length = 291

 Score = 85.4 bits (202), Expect = 2e-15
 Identities = 56/179 (31%), Positives = 83/179 (46%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M VK++P L+DNYMYL++++ T+EA  VD   PK +L+ V  +GV+L            A
Sbjct: 1   MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHA 60

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
            GN +L + RPGL V G D+RI    ++L+  + L+         L P    G       
Sbjct: 61  RGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLW 120

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
                       GD L + GCG  L  + Q       +         +FCGHE+TL+ +
Sbjct: 121 EDDCPDPPALFSGDALSVAGCGSCLEGSAQQMYQSLAELGTLPPETKVFCGHEHTLSNL 179



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 28/80 (35%), Positives = 48/80 (60%), Gaps = 1/80 (1%)
 Frame = +2

Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
           +LT+++ H  + + G ++V+CL TP HT GH+ YF+   +  +   +F+G    L     
Sbjct: 84  SLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPALFSG--DALSVAGC 141

Query: 689 GS-LKGTADQMYKALTILSS 745
           GS L+G+A QMY++L  L +
Sbjct: 142 GSCLEGSAQQMYQSLAELGT 161


>UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep:
           Glyoxylase 3 - Aedes aegypti (Yellowfever mosquito)
          Length = 302

 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 66/187 (35%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M VK +PAL+DN+MYL+V   TK AAIVDPVEP  VL+  +E GV+L            A
Sbjct: 43  MTVKKIPALKDNFMYLVVCNETKNAAIVDPVEPDRVLQVAKESGVSLNKVLTTHHHWDHA 102

Query: 441 GGNEDLIKERPG------LIVYGG-DDRIGPSQKKL---STIQSLKSVT*MYSVFLHPVI 590
           GGN DL K          L +YGG D+RI      +    T++         S   H   
Sbjct: 103 GGNADLFKRYQADTSLGPLQIYGGNDERIDNLTNPVGQDDTLEIGNLKVRCISTPCHTTS 162

Query: 591 QLGIYVIS*LLQKKVTIQLSSPGDTLFLGGCGQVL-*RARQIKCTKH*QF*AAA*PH*MF 767
            +  Y+ +   + KV       GDTLFL GCG+      +Q+      +  A      ++
Sbjct: 163 HICYYIET--PEDKVVF----TGDTLFLAGCGRFFEGTPQQMYDALITKLSALPDDTKVY 216

Query: 768 CGHEYTL 788
           CGHEY L
Sbjct: 217 CGHEYAL 223



 Score = 70.9 bits (166), Expect = 4e-11
 Identities = 38/80 (47%), Positives = 45/80 (56%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           LT  V  +   +IGNL V+C+ TPCHTT HICY++  PE   D VVFTG  TL       
Sbjct: 134 LTNPVGQDDTLEIGNLKVRCISTPCHTTSHICYYIETPE---DKVVFTGD-TLFLAGCGR 189

Query: 692 SLKGTADQMYKALTILSSCL 751
             +GT  QMY AL    S L
Sbjct: 190 FFEGTPQQMYDALITKLSAL 209


>UniRef50_Q96BZ3 Cluster: HAGHL protein; n=2; Homo sapiens|Rep:
           HAGHL protein - Homo sapiens (Human)
          Length = 203

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 38/96 (39%), Positives = 58/96 (60%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M VK++P L+DNYMYL++++ T+EA  VD   PK +L+ V  +GV+L            A
Sbjct: 1   MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHA 60

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLK 548
            GN +L + RPGL V G D+RI    ++L+  + L+
Sbjct: 61  RGNPELARLRPGLAVLGADERIFSLTRRLAHGEELR 96


>UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase
           II, partial; n=1; Pan troglodytes|Rep: PREDICTED:
           similar to glyoxalase II, partial - Pan troglodytes
          Length = 284

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 38/74 (51%), Positives = 48/74 (64%)
 Frame = +2

Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
           ALT K+ H +  ++G+LNV+CL TPCHT+GHICYFV+ P       VFTG  TL      
Sbjct: 27  ALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGD-TLFVAGCG 85

Query: 689 GSLKGTADQMYKAL 730
              +GTAD+M KAL
Sbjct: 86  KFYEGTADEMCKAL 99



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 42/127 (33%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
 Frame = +3

Query: 438 AGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVI 611
           AGGNE L++ + GL VYGGDDRIG    K++ + +L+  +        P    G   Y +
Sbjct: 3   AGGNEKLVELQSGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFV 62

Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH-*MFCGHEYTL 788
           S     +     +  GDTLF+ GCG+         C    +      P   ++CGHEYT+
Sbjct: 63  SKPGGSEPPAVFT--GDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTI 120

Query: 789 AGIXKFA 809
             + KFA
Sbjct: 121 NNL-KFA 126


>UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=13; Bacteria|Rep: Probable hydroxyacylglutathione
           hydrolase - Synechocystis sp. (strain PCC 6803)
          Length = 257

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 60/186 (32%), Positives = 81/186 (43%), Gaps = 3/186 (1%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           MD+  LPAL DNY++L+ D+   +AA+VDP E K VL  +E  G +L             
Sbjct: 1   MDIHRLPALADNYIFLLHDRQRNQAAVVDPAEAKPVLDCLETLGADLVTIYNTHHHGDHV 60

Query: 441 GGNEDLIKERPGLIVYGGDDRIG--PSQKK-LSTIQSLKSVT*MYSVFLHPVIQLGIYVI 611
           G N +L+ + P L VYGG +  G  P Q   L     L       +V+  P    G    
Sbjct: 61  GANRELLAKYPNLEVYGGVEDQGRIPGQTVFLRDGDRLSFADREATVYFVPGHTRGHIAY 120

Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLA 791
                   TI     GDT+F GGCG++             +         ++C HEYTL 
Sbjct: 121 YFAPGSGETIGDLFCGDTIFAGGCGRLFEGTPAQMVQSIGKLRQLPDQTRLWCAHEYTL- 179

Query: 792 GIXKFA 809
           G  KFA
Sbjct: 180 GNLKFA 185


>UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase
           cytoplasmic; n=2; Candidatus Pelagibacter ubique|Rep:
           Hydroxyacylglutathione hydrolase cytoplasmic -
           Candidatus Pelagibacter ubique HTCC1002
          Length = 239

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 57/178 (32%), Positives = 82/178 (46%), Gaps = 3/178 (1%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M+++I+  LQDNY YLIVDKA   A ++DP E K V+K +E++ ++L             
Sbjct: 1   MEIQIIRCLQDNYSYLIVDKAKNIACVIDPSEAKPVIKYLEDKNIHLKYILNTHHHYDHV 60

Query: 441 GGNEDLIKERPG--LIVYGGD-DRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVI 611
           GGN++L KE+ G  +I Y GD DRI      +              +F  P   LG    
Sbjct: 61  GGNKEL-KEKYGASVIGYKGDKDRIPEIDILVGDQDIWHEENFQAKIFHIPGHTLGHICF 119

Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
               ++ V       GDTLF  GCG++             +  A      ++CGHEYT
Sbjct: 120 YFYNEESV-----FTGDTLFSLGCGKIFEGTYSQMYNSLMKIKALPEKTKIYCGHEYT 172



 Score = 35.1 bits (77), Expect = 2.1
 Identities = 24/85 (28%), Positives = 35/85 (41%)
 Frame = +2

Query: 554 NLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYKALT 733
           N   +    P HT GHIC++       N+  VFTG  TL         +GT  QMY +L 
Sbjct: 101 NFQAKIFHIPGHTLGHICFYFY-----NEESVFTGD-TLFSLGCGKIFEGTYSQMYNSLM 154

Query: 734 ILSSCLTTLNVLWP*VHFGRNXKIC 808
            + +      +     +  +N K C
Sbjct: 155 KIKALPEKTKIYCGHEYTKQNSKFC 179


>UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Babesia bovis|Rep: Hydroxyacylglutathione
           hydrolase, putative - Babesia bovis
          Length = 319

 Score = 69.7 bits (163), Expect = 8e-11
 Identities = 54/189 (28%), Positives = 87/189 (46%), Gaps = 5/189 (2%)
 Frame = +3

Query: 264 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 443
           +V  +P  QDNY Y++VD   K A  VDP EP+ +L  ++E+ + L            +G
Sbjct: 68  EVITVPLFQDNYGYIVVDPDGKHAFCVDPAEPRKILSVIDERKLTLKAVFCTHKHHDHSG 127

Query: 444 GNEDLIKERPGLIVYG--GDDRIGPSQKKL-STIQSLKSVT*M-YSVFLHPVIQLGIYVI 611
           GN ++ +  PG+ VYG   +D  G +   +   +  L  +      V  H +  +  YV 
Sbjct: 128 GNLEMARIIPGIPVYGSNNEDMAGMTNGIMDGDVVRLGGLEIKGVRVPCHTLGHMLYYVT 187

Query: 612 S*LLQKKVTIQ-LSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
           +       T+Q L   GDT+F+GGCG+       +                ++CGHEYT+
Sbjct: 188 N---PSDPTMQPLMFTGDTIFIGGCGRFFEGTADMMLNIMNTVRQYRKDSLIYCGHEYTV 244

Query: 789 AGIXKFAGS 815
             + KFA +
Sbjct: 245 KNL-KFAST 252



 Score = 42.3 bits (95), Expect = 0.014
 Identities = 20/69 (28%), Positives = 33/69 (47%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           +T  +      ++G L ++ +  PCHT GH+ Y+VT P +     +   G T+       
Sbjct: 152 MTNGIMDGDVVRLGGLEIKGVRVPCHTLGHMLYYVTNPSDPTMQPLMFTGDTIFIGGCGR 211

Query: 692 SLKGTADQM 718
             +GTAD M
Sbjct: 212 FFEGTADMM 220


>UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,
           partial; n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein, partial -
           Strongylocentrotus purpuratus
          Length = 268

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 44/142 (30%), Positives = 72/142 (50%), Gaps = 3/142 (2%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           +P L+DNY YL+++KA+  AA++DP + + V + +E+Q V L            +GGN+ 
Sbjct: 6   IPYLKDNYAYLVIEKASNIAAVIDPGDAEAVQRVIEQQNVQLTAILTTHKHWDHSGGNQK 65

Query: 456 LIKERPGLIVYGGD-DRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVIS*LLQ 626
           L      L VYGG+ D +     KL    S +     ++    P   +G  +Y++     
Sbjct: 66  LKSLHSNLAVYGGERDGVPGCNHKLKDGDSFQIGGLKFTALFTPGHTVGHMVYLLD-RSD 124

Query: 627 KKVTIQLSSPGDTLFLGGCGQV 692
           K +   L + GD LFLGG G++
Sbjct: 125 KNLPNSLFT-GDILFLGGNGRM 145


>UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 2
           SCAF14661, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 400

 Score = 66.5 bits (155), Expect = 8e-10
 Identities = 48/145 (33%), Positives = 67/145 (46%), Gaps = 5/145 (3%)
 Frame = +3

Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           +KI+P   L DNY YL++D A   A +VDP +P+TV   ++E+GV L            +
Sbjct: 55  IKIIPISVLSDNYSYLVIDTAAGVAVVVDPADPQTVQAVIKEEGVVLEAILCTHKHWDHS 114

Query: 441 GGNEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
           GGN++L K      VYG   D I      LS   S+      +     P   +G  +   
Sbjct: 115 GGNKELKKLHTSCRVYGSATDNIPGLTHPLSHRDSIAFGRLHFEALFTPGHTVGHMIY-- 172

Query: 618 LLQKKVTIQLSS--PGDTLFLGGCG 686
           LL  +     SS   GD +FL GCG
Sbjct: 173 LLDGRTVGSPSSLFSGDLVFLSGCG 197


>UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to
           myofibrillogenesis regulator 1; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to myofibrillogenesis
           regulator 1 - Monodelphis domestica
          Length = 286

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 49/145 (33%), Positives = 65/145 (44%), Gaps = 5/145 (3%)
 Frame = +3

Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           VK+LP   L DNY YLI+D  +K A  VDP +P+ V  A+E++GV L            +
Sbjct: 49  VKVLPIPVLLDNYSYLIIDTQSKLAVAVDPSDPRAVQAAIEKEGVTLVAILCTHKHWDHS 108

Query: 441 GGNEDLIKERPGLIVYGG-DDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVI 611
           GGN +L +   G  VYG   D I      L     +      +     P    G  +YV+
Sbjct: 109 GGNRELRRHHRGCRVYGNPQDGIAHLTHPLCHQDMVSVGRLQFQALATPGHTRGHMVYVL 168

Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCG 686
                K  +   S  GD LFL GCG
Sbjct: 169 DGEPYKGPSCLFS--GDLLFLSGCG 191


>UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 3 SCAF15037, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 227

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 29/47 (61%), Positives = 39/47 (82%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 401
           M V++LPAL DNYMYL+VD  ++EAA+VDPVEP  V++AV++ GV L
Sbjct: 49  MRVELLPALSDNYMYLLVDVESREAAVVDPVEPLKVVEAVKKHGVRL 95


>UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 318

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 8/147 (5%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           +P L DNY Y+IVD  T  A +VDP +P+ V   + ++ + L            +GGN  
Sbjct: 56  VPFLYDNYSYIIVDITTSSAVVVDPSDPEAVKDVLNKEKLQLEAVLTTHKHWDHSGGNTS 115

Query: 456 LIKERPGLIVYGG--DDRIG--PSQKKLSTIQSL--KSVT*MYSVFLHPVIQLG--IYVI 611
           L  + P + VYG   DD  G   ++K L  I +   K     ++ F  P    G  +Y++
Sbjct: 116 LKADFPSVAVYGSELDDAPGLTHTRKPLCDISNFSGKVSQLSFTAFSTPGHTAGHVVYLL 175

Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQV 692
              +   V    S  GD LFLGGCG++
Sbjct: 176 HGAVFNSVDSLFS--GDLLFLGGCGRI 200


>UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep:
           Glyoxalase IIB - Plasmodium falciparum
          Length = 263

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 53/188 (28%), Positives = 83/188 (44%), Gaps = 7/188 (3%)
 Frame = +3

Query: 267 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 446
           V ++P L DN+ Y+I+D+ TK+AA +DPVEP  VLK +E   V L            +GG
Sbjct: 7   VLVVPVLNDNFSYVIIDEKTKKAASIDPVEPDKVLKRIETANVELEYVLCTHHHYDHSGG 66

Query: 447 NEDLIKERPGLIVYGGDDRIGPS-QKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVIS* 617
           N  + + +  + V G      P   +K+   Q ++           P    G  +Y +  
Sbjct: 67  NIRMRELKQNIKVVGSAYEPTPGVNEKVYDGQIIRLGELNIKAIHAPCHTKGHILYYVYK 126

Query: 618 LLQKKVTIQLSSP----GDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
             + K       P    GDTLF+ GCG+    + +       +         ++CGHEYT
Sbjct: 127 TDEAKQEDHKYKPILFTGDTLFIAGCGRFFEGSAKDMFKNIEKVKNMRKETLIYCGHEYT 186

Query: 786 LAGIXKFA 809
           L  + +FA
Sbjct: 187 LNNL-RFA 193



 Score = 44.0 bits (99), Expect = 0.005
 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS------VVFTGGYTLL 673
           + +KV      ++G LN++ +  PCHT GHI Y+V   +E          ++FTG  TL 
Sbjct: 90  VNEKVYDGQIIRLGELNIKAIHAPCHTKGHILYYVYKTDEAKQEDHKYKPILFTGD-TLF 148

Query: 674 RRMWAGSLKGTADQMYK 724
                   +G+A  M+K
Sbjct: 149 IAGCGRFFEGSAKDMFK 165


>UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Filobasidiella neoformans|Rep:
           Hydroxyacylglutathione hydrolase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 274

 Score = 62.9 bits (146), Expect = 9e-09
 Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 2/143 (1%)
 Frame = +3

Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           +K+LP  A  DN+MYLI+D ++ EAA+VDP +   +  AV+EQ  N+            +
Sbjct: 25  MKVLPYKARSDNWMYLIID-SSNEAAVVDPYDANKISGAVKEQRANVTSLITTHHHADHS 83

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
           GGN   +   P L VY G  +   +   +    +      +    LH        +   L
Sbjct: 84  GGNSKFLSLHPNLKVYAGSTQSPGTNTVVKDGDTFTLGQDITVKCLHTPCHTQDSICFFL 143

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQ 689
             KK   +    GDTLFL GCG+
Sbjct: 144 EDKKTGQRGVFTGDTLFLAGCGR 166


>UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 280

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 1/93 (1%)
 Frame = +3

Query: 252 VKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXX 431
           V+ + +  +P L+DNY YL+++KA+  AA++DP + + V + +E+Q V L          
Sbjct: 39  VEGVIILPIPYLKDNYAYLVIEKASNIAAVIDPGDAEAVQRVIEQQNVQLTAILTTHKHW 98

Query: 432 XXAGGNEDLIKERPGLIVYGGD-DRIGPSQKKL 527
             +GGN+ L      L VYGG+ D +    +KL
Sbjct: 99  DHSGGNQTLKSLHSNLAVYGGERDGVPGCNRKL 131


>UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20;
           Ascomycota|Rep: Function: RSP29 precursor - Aspergillus
           niger
          Length = 299

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 39/103 (37%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
 Frame = +2

Query: 506 RALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRM 682
           +++TK   H   FKIG  ++V+ L TPCHT   ICYF+   ++G+D VVFTG  TL    
Sbjct: 133 QSVTKTPAHGEVFKIGERISVKALHTPCHTQDSICYFM---QDGDDKVVFTGD-TLFIGG 188

Query: 683 WAGSLKGTADQMYKALTILSSCLTTLNVLWP*VHFGR-NXKIC 808
                +GTA +M+KAL    + L     ++P   + + N K C
Sbjct: 189 CGRFFEGTAPEMHKALNETLAALPDDTKVYPGHEYTKGNVKFC 231



 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 5/138 (3%)
 Frame = +3

Query: 291 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ----GVNLXXXXXXXXXXXXAGGNEDL 458
           +NY YL+ D+ TKE+ I+DP  P  V   ++ Q     + L            AGGN ++
Sbjct: 58  NNYAYLVTDEPTKESVIIDPANPPEVAPTLKSQIDAGKIKLTSIVNTHHHWDHAGGNNEI 117

Query: 459 IKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSV-FLHPVIQLGIYVIS*LLQKKV 635
           +K    L V GG +    S  K      +  +    SV  LH        +      +  
Sbjct: 118 LKTFGQLSVIGGKN--CQSVTKTPAHGEVFKIGERISVKALHTPCHTQDSIC--YFMQDG 173

Query: 636 TIQLSSPGDTLFLGGCGQ 689
             ++   GDTLF+GGCG+
Sbjct: 174 DDKVVFTGDTLFIGGCGR 191


>UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 260

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
 Frame = +2

Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS--VVFTGGYTLLRRM 682
           A+ + V+H    +   L ++CL TPCHT+GHICY +T P   + S  VVFTG  TL    
Sbjct: 86  AMDRHVKHGDMAEFAGLQIKCLSTPCHTSGHICYHITNPAADSTSPGVVFTGD-TLFIAG 144

Query: 683 WAGSLKGTADQMYKALTILSSCLTTLNVLWP 775
                +GTA QM  AL  +   L     ++P
Sbjct: 145 CGRFFEGTAPQMDVALNEILKNLPVETQIFP 175



 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 4/185 (2%)
 Frame = +3

Query: 267 VKILPALQDNYMYLIVDKATKEAAI-VDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 443
           VK L    DN+MY++   +   AA+ VD V  +   +  +++ +++             G
Sbjct: 4   VKSLLRRADNFMYIVKKSSEARAALLVDLVNEEDYKELADKENIDITAVLTTHHHYDHCG 63

Query: 444 GNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG--IYVIS* 617
           GNE   ++ P +++ GGD RI    + +      +           P    G   Y I+ 
Sbjct: 64  GNEGFRRQFPNVMILGGDSRIPAMDRHVKHGDMAEFAGLQIKCLSTPCHTSGHICYHITN 123

Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL-*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAG 794
                 +  +   GDTLF+ GCG+     A Q+    +           +F GHEYT+A 
Sbjct: 124 PAADSTSPGVVFTGDTLFIAGCGRFFEGTAPQMDVALNEILKNLPVETQIFPGHEYTVAN 183

Query: 795 IXKFA 809
           + KFA
Sbjct: 184 L-KFA 187


>UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 722

 Score = 60.9 bits (141), Expect = 4e-08
 Identities = 31/77 (40%), Positives = 45/77 (58%)
 Frame = +2

Query: 506 RALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMW 685
           + +TK   H   F IG++ V+ L TPCHT   IC+F+   ++GND VVFTG  TL     
Sbjct: 543 KKVTKTPPHGATFNIGDIAVKALHTPCHTQDSICFFM---QDGNDKVVFTGD-TLFHGGE 598

Query: 686 AGSLKGTADQMYKALTI 736
               +G  ++M+KAL +
Sbjct: 599 FLFFEGNGEEMHKALNV 615



 Score = 36.7 bits (81), Expect = 0.70
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = +3

Query: 291 DNYMYLIVDKATKEAAIVDPVEP 359
           DNY YL+VD  +KEA ++DP  P
Sbjct: 491 DNYAYLVVDDKSKEAVVIDPAHP 513


>UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep:
           All0580 protein - Anabaena sp. (strain PCC 7120)
          Length = 257

 Score = 60.5 bits (140), Expect = 5e-08
 Identities = 55/185 (29%), Positives = 77/185 (41%), Gaps = 6/185 (3%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M V  L AL DNY++L+ D     AA+VDP E + VLK + +    L             
Sbjct: 1   MQVIRLAALSDNYIFLLHDSHKNIAAVVDPAEAEPVLKQLAQLKAELVAIFNTHHHNDHV 60

Query: 441 GGNEDLIKERPGLIVYGGDDRIG--PSQKKL----STIQSLKSVT*MYSVFLHPVIQLGI 602
           GGN+ LI++ P + VYGG    G  P Q+        +Q    V  +  V  H    +  
Sbjct: 61  GGNQKLIQKFPQVKVYGGAKDQGRIPGQQVFLQPGDRVQFADRVAEVIFVPGHTRAHIAY 120

Query: 603 YVIS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEY 782
           Y      Q   T      GDTLF GGCG++             +  +      ++C HEY
Sbjct: 121 YFPP---QTDDTPGELFCGDTLFAGGCGRLFEGTPAQMVESLTKLRSLPENTRVWCAHEY 177

Query: 783 TLAGI 797
           TL  +
Sbjct: 178 TLKNL 182


>UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione
           hydrolase - Dictyostelium discoideum AX4
          Length = 268

 Score = 60.5 bits (140), Expect = 5e-08
 Identities = 43/148 (29%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
 Frame = +3

Query: 267 VKILPAL--QDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE--EQGVNLXXXXXXXXXXX 434
           +K+ P L  +DNY YL++D+  K A  +DP EP  V+ ++      + +           
Sbjct: 1   MKVQPVLVNKDNYSYLVIDEKNKVAIAIDPCEPNKVISSLSSISSDIKINSVFTTHHHWD 60

Query: 435 XAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS 614
            AGGN  +      + VYG D+R     KKL   + LK  +        P      +V+ 
Sbjct: 61  HAGGNNLIKTIIKDINVYGRDERFEGITKKLENNEVLKIGSLKIKTLDAPA-HTSSHVLY 119

Query: 615 *LLQKKVTIQLSS--PGDTLFLGGCGQV 692
            +  +    Q+ S   GDTLF+GGCG++
Sbjct: 120 LIEDENEPNQVKSLFTGDTLFIGGCGRL 147



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 26/73 (35%), Positives = 37/73 (50%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           +TKK+E+N   KIG+L ++ L  P HT+ H+ Y +    E N       G TL       
Sbjct: 87  ITKKLENNEVLKIGSLKIKTLDAPAHTSSHVLYLIEDENEPNQVKSLFTGDTLFIGGCGR 146

Query: 692 SLKGTADQMYKAL 730
             +G  +QMY AL
Sbjct: 147 LFEGNPEQMYNAL 159


>UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Rep:
           Isoform 3 of Q8N490 - Homo sapiens (Human)
          Length = 361

 Score = 59.7 bits (138), Expect = 9e-08
 Identities = 47/146 (32%), Positives = 65/146 (44%), Gaps = 5/146 (3%)
 Frame = +3

Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           VK+LP   L DNY YLI+D   + A  VDP +P+ V  ++E++GV L            +
Sbjct: 95  VKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKHWDHS 154

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*M-YSVFLHPVIQLG--IYVI 611
           GGN DL +      VYG      P        Q + SV  +       P    G  +Y++
Sbjct: 155 GGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLL 214

Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQ 689
                K  +   S  GD LFL GCG+
Sbjct: 215 DGEPYKGPSCLFS--GDLLFLSGCGR 238



 Score = 42.3 bits (95), Expect = 0.014
 Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           LT  + H     +G L ++ L TP HT GH+ Y +        S +F+G    L      
Sbjct: 180 LTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGC-GR 238

Query: 692 SLKGTADQMYKAL-TILSSCLTTLNVLWP 775
           + +G A+ M  +L T+L     TL  LWP
Sbjct: 239 TFEGNAETMLSSLDTVLGLGDDTL--LWP 265


>UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25;
           Euteleostomi|Rep: Probable hydrolase PNKD - Homo sapiens
           (Human)
          Length = 385

 Score = 59.7 bits (138), Expect = 9e-08
 Identities = 47/146 (32%), Positives = 65/146 (44%), Gaps = 5/146 (3%)
 Frame = +3

Query: 267 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           VK+LP   L DNY YLI+D   + A  VDP +P+ V  ++E++GV L            +
Sbjct: 119 VKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKHWDHS 178

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*M-YSVFLHPVIQLG--IYVI 611
           GGN DL +      VYG      P        Q + SV  +       P    G  +Y++
Sbjct: 179 GGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLL 238

Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQ 689
                K  +   S  GD LFL GCG+
Sbjct: 239 DGEPYKGPSCLFS--GDLLFLSGCGR 262



 Score = 42.3 bits (95), Expect = 0.014
 Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           LT  + H     +G L ++ L TP HT GH+ Y +        S +F+G    L      
Sbjct: 204 LTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGC-GR 262

Query: 692 SLKGTADQMYKAL-TILSSCLTTLNVLWP 775
           + +G A+ M  +L T+L     TL  LWP
Sbjct: 263 TFEGNAETMLSSLDTVLGLGDDTL--LWP 289


>UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;
           Ascomycota|Rep: Hydroxyacylglutathione hydrolase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 256

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 53/174 (30%), Positives = 81/174 (46%), Gaps = 9/174 (5%)
 Frame = +3

Query: 291 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEE----QGVNLXXXXXXXXXXXXAGGNEDL 458
           +NY YL+    TK  AIVDP EP++V+  ++E    + ++L            AGGNED+
Sbjct: 16  NNYAYLLTCDKTKITAIVDPAEPESVIPVIKEKTAKKEIDLQYILTTHHHYDHAGGNEDI 75

Query: 459 IKERPGLIVYGGDDRIG----PSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LLQ 626
           +   P L VYGG +  G    P  K++  +  ++ V  +++   H    +  YV S    
Sbjct: 76  LSYFPSLKVYGGKNASGVTYTPKDKEIFKVGEVQ-VEALHTP-CHTQDSICYYVSS--PS 131

Query: 627 KKVTIQLSSPGDTLFLGGCGQVL-*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
           K+        GDTLF  GCG+     A+Q+    +    A       + GHEYT
Sbjct: 132 KRAVF----TGDTLFTSGCGRFFEGDAKQMDYALNHVLAALPDDTVTYPGHEYT 181



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 30/78 (38%), Positives = 41/78 (52%)
 Frame = +2

Query: 542 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMY 721
           FK+G + V+ L TPCHT   ICY+V++P +     VFTG  TL         +G A QM 
Sbjct: 103 FKVGEVQVEALHTPCHTQDSICYYVSSPSK---RAVFTGD-TLFTSGCGRFFEGDAKQMD 158

Query: 722 KALTILSSCLTTLNVLWP 775
            AL  + + L    V +P
Sbjct: 159 YALNHVLAALPDDTVTYP 176


>UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein;
           n=1; Limnobacter sp. MED105|Rep: Metallo-beta-lactamase
           family protein - Limnobacter sp. MED105
          Length = 257

 Score = 58.0 bits (134), Expect = 3e-07
 Identities = 59/186 (31%), Positives = 82/186 (44%), Gaps = 8/186 (4%)
 Frame = +3

Query: 252 VKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXX 431
           V N  V  +PA QDNY++ IV + +K   +VDP   K+V + ++  G +L          
Sbjct: 9   VSNWSVYGIPAFQDNYLWAIVHEPSKACMVVDPGCSKSVQEFLDSHGYHLSGILVTHHHM 68

Query: 432 XXAGGNEDLI-KERPGLIVYG-GDDRIGPSQKKL---STIQSLKSVT*MYSVFLHPVIQL 596
              GG + L+ K    L VYG    RI    + +    T+     V  +  V  H V  L
Sbjct: 69  DHVGGIDALLSKAGKDLPVYGPASGRIAQINRPVREGDTVDVHCLVAQVLEVPGHTVDHL 128

Query: 597 GIYVIS*LLQKKVTIQLSSPGDTLFLGGCGQVL-*RARQI--KCTKH*QF*AAA*PH*MF 767
             YVI              PGDTLF GGCG++    A+Q+     K  QF A      ++
Sbjct: 129 A-YVIELKDTMNSEETWMFPGDTLFSGGCGRLFEGSAQQMFESLQKLNQFPANT---RVY 184

Query: 768 CGHEYT 785
           C HEYT
Sbjct: 185 CAHEYT 190


>UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Schizosaccharomyces pombe|Rep: Hydroxyacylglutathione
           hydrolase - Schizosaccharomyces pombe (Fission yeast)
          Length = 256

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
 Frame = +3

Query: 288 QDNYMYLIVDKATKEAAIVDPVEPKTVL----KAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           QDNY YL++ + T++AAIVDP E   V+    K ++ + ++L            +GGN +
Sbjct: 15  QDNYAYLLLCEETRQAAIVDPAEVNVVMPILKKKLKNKEIDLQAILTTHHHADHSGGNLN 74

Query: 456 LIKERPGLIVYGGDDRIGPS 515
           L KE P + +YGG D+ G S
Sbjct: 75  LKKEFPHVTIYGGSDQNGVS 94



 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 28/77 (36%), Positives = 41/77 (53%)
 Frame = +2

Query: 545 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYK 724
           +IGN+ ++ L TPCHT   IC++       N+  VFTG  TL         +GTA +M+ 
Sbjct: 104 RIGNVQIEALHTPCHTRDSICFYA---HSSNEHAVFTGD-TLFNAGCGRFFEGTAAEMHI 159

Query: 725 ALTILSSCLTTLNVLWP 775
           AL  + S L    V++P
Sbjct: 160 ALNAVLSSLPNNTVIYP 176


>UniRef50_UPI0000E4A799 Cluster: PREDICTED: similar to CG4365-PC,
           partial; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to CG4365-PC, partial -
           Strongylocentrotus purpuratus
          Length = 68

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 23/35 (65%), Positives = 30/35 (85%)
 Frame = +3

Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPK 362
           +M + +L AL+DNYMYL+ D+ATKEAAIVDPV P+
Sbjct: 33  DMKITLLSALEDNYMYLLTDEATKEAAIVDPVNPE 67


>UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep:
           Glyoxalase II - Oryza sativa (Rice)
          Length = 336

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 52/187 (27%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
 Frame = +3

Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 437
           ++ ++++P LQDNY Y++ D  T    +VDP E   ++ A+E++  NL            
Sbjct: 82  SLQIELVPCLQDNYAYILHDVDTGTVGVVDPSEATPIINALEKRNQNLTYILNTHHHYDH 141

Query: 438 AGGNEDLIKERPGLIVYGG---DDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYV 608
            GGN +L K + G  V G     DRI      LS     +  T M++     V++   + 
Sbjct: 142 TGGNLEL-KAKYGAKVIGSAKDRDRIPGIDITLS-----EGDTWMFAGHQVLVMETPGHT 195

Query: 609 IS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
              +            GDTLF   CG++     Q   +   +  A      ++CGHEYTL
Sbjct: 196 SGHVCYHFPGSGAIFTGDTLFSLSCGKLFEGTPQQMYSSLQKIIALPDETRVYCGHEYTL 255

Query: 789 AGIXKFA 809
           +   KFA
Sbjct: 256 SN-SKFA 261



 Score = 35.1 bits (77), Expect = 2.1
 Identities = 21/51 (41%), Positives = 26/51 (50%)
 Frame = +2

Query: 578 TPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYKAL 730
           TP HT+GH+CY    P  G    +FTG  TL         +GT  QMY +L
Sbjct: 191 TPGHTSGHVCYHF--PGSG---AIFTGD-TLFSLSCGKLFEGTPQQMYSSL 235


>UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=8; Trypanosomatidae|Rep:
           Hydroxyacylglutathione hydrolase, putative - Leishmania
           major
          Length = 295

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 25/74 (33%), Positives = 38/74 (51%)
 Frame = +2

Query: 509 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWA 688
           A+TK V    + ++GNL+V+ +  PCHT GH+ Y V  P+  ND V    G T+      
Sbjct: 113 AVTKPVREGDRVQVGNLSVEVIDAPCHTRGHVLYKVQHPQHPNDGVALFTGDTMFIAGIG 172

Query: 689 GSLKGTADQMYKAL 730
              +G    M +A+
Sbjct: 173 AFFEGDEKDMCRAM 186



 Score = 33.1 bits (72), Expect = 8.6
 Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
 Frame = +3

Query: 267 VKILPALQDNYMYLIVDKATKEAAIVD-PVEPKTVLKAVEE 386
           V ++P L+DN+ YLI D  T   A VD   + K +L  +EE
Sbjct: 15  VTVVPTLKDNFSYLINDHTTHTLAAVDVNADYKPILTYIEE 55


>UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep:
           Hydroxyacylglutathione hydrolase - Desulfuromonas
           acetoxidans DSM 684
          Length = 249

 Score = 53.2 bits (122), Expect = 8e-06
 Identities = 53/175 (30%), Positives = 73/175 (41%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           +++ +L A  DNY Y+I D  T  A  +DP E + VL  +E+ G +L             
Sbjct: 2   VEITLLQAHDDNYAYMISDGDTTIA--IDPGEAEPVLDYLEKHGRSLSLILNTHMHQDHC 59

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
           GGN  L K   G  + GGD+RI    + L     L  +     V   P    G      L
Sbjct: 60  GGNLTL-KRLTGCHIAGGDERIVGVDRLLQEDSVLPGLPWPLQVMHTPGHTRGDCCYY-L 117

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
            Q +        GDTLF GGCG+V     +       +  A      ++CGHEYT
Sbjct: 118 PQCEALF----CGDTLFSGGCGRVFEGTMEQLYHSLQKITALPETTRLYCGHEYT 168


>UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily
           protein; n=7; Bacteria|Rep: Metallo-beta-lactamase
           superfamily protein - marine gamma proteobacterium
           HTCC2143
          Length = 260

 Score = 53.2 bits (122), Expect = 8e-06
 Identities = 53/180 (29%), Positives = 80/180 (44%), Gaps = 3/180 (1%)
 Frame = +3

Query: 267 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 446
           ++ +PA  DNY++ I D  + +AA+VDP E   V +A+  Q + L             GG
Sbjct: 4   IEPIPAFNDNYIWCIYDDDSGKAAVVDPGEAGPVEEALLAQQLQLETILITHHHFDHTGG 63

Query: 447 NEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LL 623
            E L K R  + VYG  + +I     +L    S+      +++   P   L    I+   
Sbjct: 64  IEALTKHR-DIPVYGPKNHQIASITHRLDEQSSMSLFGLDFTILEVPGHTLD--HIALYC 120

Query: 624 QKKVTIQ-LSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*P-H*MFCGHEYTLAGI 797
           +   T Q +   GDTLF GGCG++             Q  AA  P   ++C HEYTL  +
Sbjct: 121 EDTGTGQPVLFCGDTLFAGGCGRIF-EGNPTMMLNSLQKLAALPPTTEIYCAHEYTLGNL 179


>UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB;
           n=4; Legionella pneumophila|Rep: Hydroxyacylglutathione
           hydrolase GloB - Legionella pneumophila (strain Corby)
          Length = 254

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 49/184 (26%), Positives = 75/184 (40%), Gaps = 1/184 (0%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M +  + A  DNY++  +DK       VDP E   +++  +   + L             
Sbjct: 1   MTILPISAFSDNYIWAFIDKIAGVLDCVDPGEAAPIIRFAQSNQLTLRTILLTHHHYDHI 60

Query: 441 GGNEDLIKERPGLIVYGG-DDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
           GG + LIK+ P   VYG  D+RI      +   QS++  +  + +  +P      ++   
Sbjct: 61  GGVDSLIKQWPSCKVYGPIDERINNVTHPIKQGQSVQVGSLHFHILFNPG-HTSTHISYY 119

Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
             QK         GDTLF  GCG+V     +        F        +FC HEYTL  +
Sbjct: 120 EPQKGWLF----CGDTLFSAGCGRVFDGTIEELHESLLLFKKLPRNTKVFCAHEYTLQNL 175

Query: 798 XKFA 809
            KFA
Sbjct: 176 -KFA 178



 Score = 33.5 bits (73), Expect = 6.5
 Identities = 20/75 (26%), Positives = 39/75 (52%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           +T  ++     ++G+L+   LF P HT+ HI Y+   P++G    +F G  TL       
Sbjct: 86  VTHPIKQGQSVQVGSLHFHILFNPGHTSTHISYY--EPQKG---WLFCGD-TLFSAGCGR 139

Query: 692 SLKGTADQMYKALTI 736
              GT ++++++L +
Sbjct: 140 VFDGTIEELHESLLL 154


>UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=1; Acinetobacter sp. ADP1|Rep: Putative
           hydroxyacylglutathione hydrolase - Acinetobacter sp.
           (strain ADP1)
          Length = 244

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 31/85 (36%), Positives = 46/85 (54%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           +T  ++H   FK  +LNV+ L TP HT GH+ YF+   E G+   +F G  TL       
Sbjct: 92  ITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFI--EETGS---LFCGD-TLFAMGCGR 145

Query: 692 SLKGTADQMYKALTILSSCLTTLNV 766
             +G+ +QMY +L  L++  TT  V
Sbjct: 146 VFEGSFEQMYHSLNRLAALPTTTKV 170



 Score = 39.1 bits (87), Expect = 0.13
 Identities = 44/169 (26%), Positives = 69/169 (40%), Gaps = 3/169 (1%)
 Frame = +3

Query: 294 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 473
           NY++++ D  T+E  +VDP E   V +  E+  V +             GG  DLI +  
Sbjct: 17  NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLI-DGS 75

Query: 474 GLIVYGGDDRIGPSQKKLSTIQ---SLKSVT*MYSVFLHPVIQLGIYVIS*LLQKKVTIQ 644
            + VYG  + +         +Q     K       V   P   LG  V    +++  ++ 
Sbjct: 76  HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVY--FIEETGSLF 133

Query: 645 LSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLA 791
               GDTLF  GCG+V   + +       +  A      ++C HEYTLA
Sbjct: 134 C---GDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLA 179


>UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4;
           Proteobacteria|Rep: Hydroxyacylglutathione hydrolase -
           Pseudomonas stutzeri (strain A1501)
          Length = 292

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 54/193 (27%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
 Frame = +3

Query: 237 PRGPPVKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE-EQGVNLXXXX 413
           P G P     ++ LPA  DNY++L+ D A +    VDP +   VL  +    G  L    
Sbjct: 28  PLGDP-SMFKIEALPAFTDNYIWLLQDDAARRCVAVDPGDAAPVLNWLSAHPGWQLSDIL 86

Query: 414 XXXXXXXXAGGNEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVI 590
                    GG E L K + G  VYG   ++I    + LS  Q ++ +     +   P  
Sbjct: 87  VTHHHHDHVGGVERL-KAQTGARVYGPAAEKIPARDEALSDGQRIEVLGKRLQIIAVPGH 145

Query: 591 QLGIYVIS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFC 770
            LG ++            LS  GDTLF  GCG++     +       +  +A     ++C
Sbjct: 146 TLG-HIAYFHADPDQPWLLS--GDTLFAAGCGRLFEGTPEQMFESLTRLASAPDHTLVYC 202

Query: 771 GHEYTLAGIXKFA 809
            HEYTL+ + +FA
Sbjct: 203 THEYTLSNL-RFA 214


>UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Pseudomonadales|Rep: Hydroxyacylglutathione hydrolase -
           Pseudomonas mendocina ymp
          Length = 257

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 47/184 (25%), Positives = 74/184 (40%), Gaps = 1/184 (0%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG-VNLXXXXXXXXXXXX 437
           + +  LPA  DNY++L+ D  ++  A+VDP +   VL  +E  G   L            
Sbjct: 2   IQIDALPAFNDNYIWLLQDPISRRCAVVDPGDAAPVLAWLEAHGDWTLSDILITHHHFDH 61

Query: 438 AGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
            GG E L K     +     ++I      L     ++ +   + +   P   LG      
Sbjct: 62  VGGVEQLKKATGARVAGPAAEKIPARDVDLGDNDLIEVLGLRFQIMAVPGHTLGH----- 116

Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
           +        L   GDTLF GGCG++     Q       +  A      ++C HEYTL+ +
Sbjct: 117 IAYYHAEQNLLLCGDTLFAGGCGRLFEGTPQQMHQSLSRLAALPGATRVYCTHEYTLSNL 176

Query: 798 XKFA 809
            +FA
Sbjct: 177 -RFA 179


>UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 659

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 15/116 (12%)
 Frame = +2

Query: 506 RALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRM 682
           +++TK   H   FKIG+ ++V  L TPCHT   ICYF+   ++G    VFTG    +  M
Sbjct: 468 QSVTKTPAHGEVFKIGDRISVTALHTPCHTQDSICYFM---QDGEQKAVFTGDTLFIGGM 524

Query: 683 --WAGS-----------LKGTADQMYKALTILSSCLTTLNVLWP*VHFGR-NXKIC 808
             W  +            +GTA +M+KAL    + L     ++P   + + N K C
Sbjct: 525 TEWINAESSAAAGCGRFFEGTAPEMHKALNETLASLPEDTKVYPGHEYTKGNVKFC 580



 Score = 44.8 bits (101), Expect = 0.003
 Identities = 40/137 (29%), Positives = 64/137 (46%), Gaps = 7/137 (5%)
 Frame = +3

Query: 291 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ----GVNLXXXXXXXXXXXXAGGNEDL 458
           +NY YL+ D+ TK++ I+DP  P  V+  +E Q     +NL            AGGN ++
Sbjct: 394 NNYAYLVTDEPTKQSVIIDPANPPEVVPELEAQTKAGKINLTAIVNTHHHWDHAGGNNEV 453

Query: 459 IKERPGLIVYGGDDRI---GPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LLQK 629
           +K     ++ G D +     P+  ++  I    SVT +++   H    +  Y +    QK
Sbjct: 454 LKTFKVPVIGGKDCQSVTKTPAHGEVFKIGDRISVTALHTP-CHTQDSI-CYFMQDGEQK 511

Query: 630 KVTIQLSSPGDTLFLGG 680
            V       GDTLF+GG
Sbjct: 512 AV-----FTGDTLFIGG 523


>UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Marinobacter|Rep: Hydroxyacylglutathione hydrolase -
           Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 /
           VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
           11845))
          Length = 263

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 45/187 (24%), Positives = 81/187 (43%), Gaps = 4/187 (2%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M +  +PA  DNY++ + +  + +  IVDP + K VL  + + G +              
Sbjct: 1   MRIHPVPAFSDNYIWCLTNLESGKTLIVDPGQAKPVLDYLSDSGFSADTILITHHHPDHT 60

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
           GG ++L ++ P L + G  D   P +   +T+ +   V  ++      V+ +  + +  +
Sbjct: 61  GGVKELQQQYPDLRIVGPTD--SPFKGATNTVHAGDEV--VWEGITFNVLAVPGHTLDHI 116

Query: 621 LQKKVTIQLSSP----GDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
                T     P    GDTLF+ GCG++     +   T             ++C HEYTL
Sbjct: 117 AYYSDTQVNDKPVLFCGDTLFVCGCGRLFEGTPEQMHTSLQTLRDLPDNTAVYCAHEYTL 176

Query: 789 AGIXKFA 809
           A + +FA
Sbjct: 177 ANL-RFA 182


>UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 268

 Score = 50.0 bits (114), Expect = 7e-05
 Identities = 41/183 (22%), Positives = 71/183 (38%), Gaps = 4/183 (2%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGV---NLXXXXXXXXXX 431
           M +  +   +DNY Y++       A  VD  + + V  A E+ G+   N+          
Sbjct: 1   MKIHPVAVREDNYAYILQSSVDGRAVFVDVFDVEAVSGAAEKLGIPNENVVGLLTTHHHF 60

Query: 432 XXAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSV-FLHPVIQLGIYV 608
             +GGNE      PG  +YGG D+I    K +     +  +    S+  +        ++
Sbjct: 61  DHSGGNEAFAHAYPGRPIYGGSDKIPALTKLVHDADRISELLGGVSIECVATPCHTQDHI 120

Query: 609 IS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
              +            GDTLF+ GCG+      Q   +   +  +      ++CGHEYT 
Sbjct: 121 CYHVTDTTTAQSGVFTGDTLFISGCGRFFEGHPQQMLSAMDRLSSLPDHTLVYCGHEYTK 180

Query: 789 AGI 797
           + +
Sbjct: 181 SNV 183



 Score = 49.6 bits (113), Expect = 9e-05
 Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
 Frame = +2

Query: 509 ALTKKVEHNTKFK--IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRM 682
           ALTK V    +    +G ++++C+ TPCHT  HICY VT       S VFTG  TL    
Sbjct: 87  ALTKLVHDADRISELLGGVSIECVATPCHTQDHICYHVTDTTTA-QSGVFTGD-TLFISG 144

Query: 683 WAGSLKGTADQMYKALTILSS 745
                +G   QM  A+  LSS
Sbjct: 145 CGRFFEGHPQQMLSAMDRLSS 165


>UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Psychrobacter|Rep: Hydroxyacylglutathione hydrolase -
           Psychrobacter sp. PRwf-1
          Length = 259

 Score = 49.6 bits (113), Expect = 9e-05
 Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 3/142 (2%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           +PA  DNY++ +V+   K+A ++DP + + V   +E+ G+ L             GG  +
Sbjct: 8   IPAFTDNYIWALVNDTNKQAIVIDPGQAQPVADYLEQYGLELTAIWITHHHHDHVGGVAE 67

Query: 456 LIKERPGL-IVYGGDDRIGPSQ--KKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LLQ 626
           L +  P   +V   +  + P Q  K+ S++ +      +++V  H    L  YV+     
Sbjct: 68  LRELYPMTHVVASAEHGVKPDQVVKEGSSVSAWGYTAQVWAVPGHTQSHLA-YVLDKEGH 126

Query: 627 KKVTIQLSSPGDTLFLGGCGQV 692
           K+V       GDTLF  GCG+V
Sbjct: 127 KQVFC-----GDTLFSAGCGRV 143


>UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathione
           hydrolase-like isoform 2; n=1; Pan troglodytes|Rep:
           PREDICTED: hydroxyacylglutathione hydrolase-like isoform
           2 - Pan troglodytes
          Length = 285

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 21/44 (47%), Positives = 29/44 (65%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG 392
           M VK++P L+DNYMYL++++ T+EA  VD   PK V      QG
Sbjct: 1   MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRVRAGRGPQG 44



 Score = 44.0 bits (99), Expect = 0.005
 Identities = 24/63 (38%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
 Frame = +2

Query: 545 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGS-LKGTADQMY 721
           + G ++V+CL TP HT GH+ YF+   +  +   +F+G    L     GS L+G+A QMY
Sbjct: 91  QFGAIHVRCLLTPGHTGGHMSYFLWEDDCPDPPALFSG--DALSVAGCGSCLEGSAQQMY 148

Query: 722 KAL 730
           ++L
Sbjct: 149 QSL 151


>UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Neptuniibacter caesariensis|Rep:
           Metallo-beta-lactamase superfamily protein -
           Neptuniibacter caesariensis
          Length = 257

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 49/175 (28%), Positives = 76/175 (43%), Gaps = 1/175 (0%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           +PA  DNY+++I    +   A+VDP +   VL  +EE  + L             GG E 
Sbjct: 7   IPAFSDNYIWVIASPDSNMVAVVDPGDEAPVLAYLEENNLQLTAILITHHHNDHTGGVEA 66

Query: 456 LIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*M-YSVFLHPVIQLGIYVIS*LLQKK 632
           L K+R    VYG  +   P Q     +    S+  M  SV +  +    +  IS    ++
Sbjct: 67  L-KDRFKTPVYGPAN--SPFQGITHPLNDGDSIQLMGASVAIKAIPGHTLDHIS-YYSER 122

Query: 633 VTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
              QL   GDTLFL GCG++     +        F +      ++C HEY++A +
Sbjct: 123 HKPQLFC-GDTLFLAGCGRLFEGTAKQMLNAMNYFASLPDDTEVYCTHEYSMANL 176


>UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1,
           mitochondrial precursor; n=12; core eudicotyledons|Rep:
           Hydroxyacylglutathione hydrolase 1, mitochondrial
           precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 331

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 26/78 (33%), Positives = 41/78 (52%)
 Frame = +3

Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 437
           ++ ++++P  +DNY YL+ D+ T    +VDP E   V++A+  +  NL            
Sbjct: 77  SLKIELVPCSKDNYAYLLHDEDTGTVGVVDPSEAAPVIEALSRKNWNLTYILNTHHHDDH 136

Query: 438 AGGNEDLIKERPGLIVYG 491
            GGN +L KER G  V G
Sbjct: 137 IGGNAEL-KERYGAKVIG 153


>UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=40; Gammaproteobacteria|Rep: Probable
           hydroxyacylglutathione hydrolase - Escherichia coli
           O157:H7
          Length = 251

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 47/183 (25%), Positives = 78/183 (42%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M++  +PA  DNY++++ D+A +   IVDP + + VL A+                    
Sbjct: 1   MNLNSIPAFDDNYIWVLNDEAGR-CLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHV 59

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
           GG ++L+++ P ++VYG  +    +Q K +T       T         VI    + +  +
Sbjct: 60  GGVKELVEKFPQIVVYGPQE----TQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHI 115

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGIX 800
                       GDTLF GGCG++             +  A      + C HEYTL+ + 
Sbjct: 116 CYFSKPYLFC--GDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTLVCCAHEYTLSNM- 172

Query: 801 KFA 809
           KFA
Sbjct: 173 KFA 175



 Score = 43.2 bits (97), Expect = 0.008
 Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +2

Query: 500 QDRALTKKVEHN-TKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLR 676
           QD+  T+ V+   T F +G+     + TP HT GHICYF + P       +F+GG   L 
Sbjct: 81  QDKGTTQVVKDGETAFVLGH-EFSVIATPGHTLGHICYF-SKPYLFCGDTLFSGGCGRL- 137

Query: 677 RMWAGSLKGTADQMYKALTILSS 745
                  +GTA QMY++L  LS+
Sbjct: 138 ------FEGTASQMYQSLKKLSA 154


>UniRef50_UPI0000DAE586 Cluster: hypothetical protein
           Rgryl_01000658; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000658 - Rickettsiella
           grylli
          Length = 257

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 44/183 (24%), Positives = 77/183 (42%), Gaps = 4/183 (2%)
 Frame = +3

Query: 261 MDVKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 434
           M +++LP  A +DNY++ ++++ TK   IVDP E K VL  +++  + L           
Sbjct: 1   MTIQLLPILAFKDNYIWCLINEETKHCLIVDPGEAKPVLAQLKQLNLTLDALLITHHHWD 60

Query: 435 XAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS 614
              G   ++   P  +        GPS++K+  +    + T    +   P  ++ + +  
Sbjct: 61  HTNGIRSILNHYPVPV-------FGPSKEKIVGVTHPVNETDKIELTHWPSFEI-LAIPG 112

Query: 615 *LLQKKVTI--QLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
             L         L   GDTLF  GCG++             +         ++CGHEYTL
Sbjct: 113 HTLGHIAYYGNHLLFCGDTLFTAGCGRLFEGTPDQMLNSLEKLAQLPDETQIYCGHEYTL 172

Query: 789 AGI 797
           A +
Sbjct: 173 ANL 175


>UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep:
           Glyoxylase - Ostreococcus tauri
          Length = 512

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 21/58 (36%), Positives = 29/58 (50%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGN 449
           +P + DNY YL+VD  T+EA  +DP +P+  + A    G  L            AGGN
Sbjct: 149 IPFMNDNYSYLVVDADTREACAIDPADPERAVDAARRCGAKLTTVLTTHKHHDHAGGN 206


>UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Mariprofundus ferrooxydans PV-1|Rep:
           Hydroxyacylglutathione hydrolase - Mariprofundus
           ferrooxydans PV-1
          Length = 262

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 47/181 (25%), Positives = 75/181 (41%), Gaps = 1/181 (0%)
 Frame = +3

Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 437
           N  V  LP L+DNY+YLI   A+    ++DP E  +V +A  E G  L            
Sbjct: 8   NFTVHQLPVLKDNYIYLIEAHASSALIVIDPAEAVSVRRACRELGKPLTHIFNTHHHWDH 67

Query: 438 AGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
             GN+ L K+   +++    D        L   ++   +    ++ +  V       I+ 
Sbjct: 68  TDGNQSLKKDFGAVVIGAAHDAERIPGINLKVSEASPPLVDGLNIRVLDVAGHTRGHIAY 127

Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH-*MFCGHEYTLAG 794
           LL   +       GDTLF  GCG++       +  +  Q  A    +  ++C HEYTLA 
Sbjct: 128 LLDDALFC-----GDTLFGAGCGRLF-EGTPAQMWQSLQKIAQLDGNTRIYCAHEYTLAN 181

Query: 795 I 797
           +
Sbjct: 182 L 182


>UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase,
           mitochondrial precursor; n=10; Saccharomycetales|Rep:
           Hydroxyacylglutathione hydrolase, mitochondrial
           precursor - Saccharomyces cerevisiae (Baker's yeast)
          Length = 285

 Score = 47.6 bits (108), Expect = 4e-04
 Identities = 26/73 (35%), Positives = 39/73 (53%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           +T+  ++  ++ +GNL V C+ TPCHT   ICY++   E G +  +FTG  TL       
Sbjct: 106 VTEVPDNLQQYHLGNLRVTCIRTPCHTKDSICYYIKDLETG-EQCIFTGD-TLFIAGCGR 163

Query: 692 SLKGTADQMYKAL 730
             +GT   M  AL
Sbjct: 164 FFEGTGRDMDMAL 176


>UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Saccharomycetaceae|Rep: Hydroxyacylglutathione hydrolase
           - Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 282

 Score = 47.2 bits (107), Expect = 5e-04
 Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 6/139 (4%)
 Frame = +3

Query: 291 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ--GVNLXXXXXXXXXXXXAGGNEDLIK 464
           DNY YL+VD  +K A ++DP  P  V + ++E+     L            + GN++  +
Sbjct: 41  DNYAYLLVDDRSKNAWLIDPAVPLEVNEFIKEKKPKYELKAIVNTHHHYDHSDGNKEFHR 100

Query: 465 ERPGLIVYGGDD----RIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LLQKK 632
           + P L +  G D       PS +++  +    SVT +++   H    +  YV      +K
Sbjct: 101 KYPDLPIIAGKDSPLVTYTPSHEEVIDLGDDLSVTALHTP-CHTQDSICYYVKDAKTGEK 159

Query: 633 VTIQLSSPGDTLFLGGCGQ 689
                   GDTLF+ GCG+
Sbjct: 160 AVF----TGDTLFISGCGR 174


>UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16;
           Alphaproteobacteria|Rep: Glyoxalase II - Bradyrhizobium
           japonicum
          Length = 255

 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 46/182 (25%), Positives = 72/182 (39%)
 Frame = +3

Query: 264 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 443
           +++    L DN+ YLI D  TK  A +D  E   +LKA+E +G  L             G
Sbjct: 4   EIRTFSCLNDNFGYLIHDVETKATASIDAPEAGPILKALEREGWQLTDILITHHHGDHVG 63

Query: 444 GNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*LL 623
           G  +L K +    V    D+          + +   V       L  V++   + +  + 
Sbjct: 64  GVAEL-KHKYNCRVVAPHDKTTAIANVDLRVANADVV--KVGNLLARVVETPGHTLDHIS 120

Query: 624 QKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGIXK 803
               T +     DTLF  GCG+V      +      +  A      ++CGHEYT + + K
Sbjct: 121 YVFDTEKTVFAADTLFSIGCGRVFEGTYPMMWDSLLKLRALPDDFKLYCGHEYTASNV-K 179

Query: 804 FA 809
           FA
Sbjct: 180 FA 181


>UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=2; Theileria|Rep: Hydroxyacylglutathione
           hydrolase, putative - Theileria annulata
          Length = 362

 Score = 46.8 bits (106), Expect = 7e-04
 Identities = 24/78 (30%), Positives = 35/78 (44%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           +T  V+H      GNL ++CL   CHT GHI Y+V  P   +   +   G TL       
Sbjct: 195 VTLPVKHEQTLTFGNLVIKCLKASCHTLGHIMYYVYHPSNDHQQPLLFSGDTLFISGCGR 254

Query: 692 SLKGTADQMYKALTILSS 745
             +G A  M + +  + S
Sbjct: 255 FFEGDARSMMEIVETVKS 272



 Score = 41.5 bits (93), Expect = 0.025
 Identities = 19/46 (41%), Positives = 27/46 (58%)
 Frame = +3

Query: 264 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 401
           +V I+P LQDNY Y++ D  +  A  VDPVE + V    +E  + L
Sbjct: 85  EVLIVPVLQDNYSYVLKDPESSNALCVDPVEYEKVYNVCKENDLEL 130


>UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 536

 Score = 44.0 bits (99), Expect = 0.005
 Identities = 18/32 (56%), Positives = 24/32 (75%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVL 371
           +P L DNY YLI+  ATK+ A+VDP +PK V+
Sbjct: 208 VPLLADNYAYLILSFATKKCAVVDPADPKLVM 239


>UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Marinomonas|Rep: Hydroxyacylglutathione hydrolase -
           Marinomonas sp. MWYL1
          Length = 257

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 39/145 (26%), Positives = 61/145 (42%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M +  LPA  DNY+++I DK +     VDP +   VL    E    L             
Sbjct: 1   MTIFPLPAFNDNYIWIIQDKDSSGIWAVDPGKADVVLNFCHEYQKTLTGILITHHHKDHT 60

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
           GG  +L K+     VYG +         +     +   + +++V   P   L    +   
Sbjct: 61  GGVAEL-KQHSNCPVYGPEHLTELVTHPVDDGDRILVFSKVFTVIATPGHTLD--HLCYF 117

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL 695
            +++  I LS  GDTLF GGCG+++
Sbjct: 118 SEQETPILLS--GDTLFKGGCGRIM 140


>UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=44; Bacteria|Rep: Hydroxyacylglutathione
           hydrolase precursor - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 269

 Score = 43.6 bits (98), Expect = 0.006
 Identities = 49/186 (26%), Positives = 81/186 (43%), Gaps = 8/186 (4%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           +PA  DNY++ I +   K A +VDP +   VL+ +++ G+ L             GG   
Sbjct: 12  IPAFDDNYIWCIHNG--KSALVVDPGDAVPVLEYLKQSGLRLTGILITHHHADHTGGILA 69

Query: 456 LI----KERPGLIVYG----GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVI 611
           L+    K+ P +   G    G  +I  +  K+  I S +    +Y V  H +  +  +  
Sbjct: 70  LLDALGKDIPVIGPAGSNIPGRTQIAKADDKIE-ITSPRISLQVYEVPGHTLSHIAYFA- 127

Query: 612 S*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLA 791
              +Q  V   +   GDTLF  GCG++             +F +      ++C HEYTL+
Sbjct: 128 --NMQANVVEPMLFCGDTLFASGCGRLFEGTPTQMTQSLAKFASLPKNTLVYCTHEYTLS 185

Query: 792 GIXKFA 809
            I +FA
Sbjct: 186 NI-RFA 190


>UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily
           hydrolase; n=7; Prochlorococcus marinus|Rep:
           Metallo-beta-lactamase superfamily hydrolase -
           Prochlorococcus marinus
          Length = 253

 Score = 43.2 bits (97), Expect = 0.008
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
 Frame = +2

Query: 515 TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN-DSVVFTGGYTLLRRMWAG 691
           TK V  N +  I    ++ +  P HT+ HIC+F+   +E   D V+F G  TL       
Sbjct: 94  TKSVVDNEELDILGQKIKVIEVPGHTSNHICFFLQGSKESKIDPVLFCGD-TLFGAGCGR 152

Query: 692 SLKGTADQMYKALTILSS 745
             +GT +QM+ +L+ +++
Sbjct: 153 LFEGTPEQMFNSLSRINN 170



 Score = 37.1 bits (82), Expect = 0.53
 Identities = 42/179 (23%), Positives = 71/179 (39%), Gaps = 5/179 (2%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           +P L DN +++ V +  K+A +VDP   + V+  ++  G++L             GG ++
Sbjct: 13  IPVLMDNIIWIWVKE--KQAIVVDPAISEPVINLLKGNGLSLHSVLQTHHHEDHIGGTQE 70

Query: 456 LIKERPGLIVYGGD---DRIGPSQKKLSTIQSLKSVT*MYSVFLHP--VIQLGIYVIS*L 620
           LI   P   V       DRI    K +   + L  +     V   P        + +   
Sbjct: 71  LINVWPSASVIAAKSDLDRIQFQTKSVVDNEELDILGQKIKVIEVPGHTSNHICFFLQGS 130

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
            + K+   L   GDTLF  GCG++     +       +         ++C HEYT A +
Sbjct: 131 KESKIDPVLFC-GDTLFGAGCGRLFEGTPEQMFNSLSRINNLPKNTKIYCAHEYTEANL 188


>UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein;
           n=9; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Methylococcus capsulatus
          Length = 256

 Score = 42.7 bits (96), Expect = 0.011
 Identities = 24/77 (31%), Positives = 38/77 (49%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           +++  +P L+DNY+YL+ +  +   A VDP     VL+A++ +G  L             
Sbjct: 2   LEILQIPVLEDNYVYLLHEPGSGATAAVDPAVAGPVLEALDARGWRLGHVLNTHHHGDHV 61

Query: 441 GGNEDLIKERPGLIVYG 491
           GGN +L K   G  V G
Sbjct: 62  GGNLEL-KAATGCTVVG 77



 Score = 34.3 bits (75), Expect = 3.7
 Identities = 18/64 (28%), Positives = 37/64 (57%)
 Frame = +2

Query: 539 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQM 718
           +F++G+ + + L  P HT+GH+ ++       +D+ +F G  TL         +G+A+QM
Sbjct: 97  EFRLGSASARMLDVPGHTSGHVAFWFE-----DDAALFCGD-TLFALGCGRLFEGSAEQM 150

Query: 719 YKAL 730
           +++L
Sbjct: 151 WRSL 154


>UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrolase
           with metallo- hydrolase/oxidoreductase domain; n=4;
           Proteobacteria|Rep: Putative hydroxyacylglutathione
           hydrolase with metallo- hydrolase/oxidoreductase domain
           - Pseudoalteromonas tunicata D2
          Length = 261

 Score = 42.7 bits (96), Expect = 0.011
 Identities = 32/144 (22%), Positives = 62/144 (43%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           + VK + A +DNY++ I++   +   +VDP + + V+  + E  + L             
Sbjct: 4   LQVKPIKAFKDNYIWAIINTENQHCVVVDPGDAEPVIAFISEHQLTLSAILITHHHWDHT 63

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
            G E L   +  L VYG  +       +  +  ++  +T  + +  H +   G + +  +
Sbjct: 64  NGVEKLCSLQASLPVYGPKNSPFAGITEPLSANTVCQLT-DFDLSFHILATPG-HTLDHI 121

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQV 692
              +        GDTLF GGCG++
Sbjct: 122 CYYEPQQDWLFCGDTLFSGGCGRL 145



 Score = 36.3 bits (80), Expect = 0.93
 Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGN--LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMW 685
           +T+ +  NT  ++ +  L+   L TP HT  HICY+     E     +F G  TL     
Sbjct: 89  ITEPLSANTVCQLTDFDLSFHILATPGHTLDHICYY-----EPQQDWLFCGD-TLFSGGC 142

Query: 686 AGSLKGTADQMYKALTILS 742
               +GTADQM++++  LS
Sbjct: 143 GRLFEGTADQMFQSMVKLS 161


>UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=5; Sphingomonadaceae|Rep:
           Hydroxyacylglutathione hydrolase precursor -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 246

 Score = 42.3 bits (95), Expect = 0.014
 Identities = 42/181 (23%), Positives = 73/181 (40%), Gaps = 4/181 (2%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           +++  +P L DNY++L+ + A+    +VDP     VL A + +G  +             
Sbjct: 4   LEIVRIPVLSDNYVWLVHEPASGATMVVDPAVADPVLDAAKARGWAITDIWNTHWHPDHT 63

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPS--QKKLSTIQSL--KSVT*MYSVFLHPVIQLGIYV 608
           GGN   IKE      +GG    GP+   +++ T+  L     T      +  V  +  + 
Sbjct: 64  GGNA-AIKE--AAKAWGGCTITGPAAEHERIPTLDVLVKGGDTVRLGDHVADVWDVPAHT 120

Query: 609 IS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTL 788
              +            GDT+F  GCG++     +       +  A      ++C HEYTL
Sbjct: 121 AGHIAYHFADDAAIFVGDTMFAMGCGRLFEGTAEQMFANMQKLRALDDATRVYCAHEYTL 180

Query: 789 A 791
           +
Sbjct: 181 S 181


>UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Psychromonas|Rep: Hydroxyacylglutathione hydrolase -
           Psychromonas ingrahamii (strain 37)
          Length = 256

 Score = 41.9 bits (94), Expect = 0.019
 Identities = 42/147 (28%), Positives = 66/147 (44%), Gaps = 4/147 (2%)
 Frame = +3

Query: 264 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 443
           +V  + A +DNY++LI D  ++   IVDP +   VL  +E+Q + +             G
Sbjct: 3   NVITIKAFEDNYIWLIKDSQSQHCIIVDPGDAAPVLTILEDQKLIVDAILLTHHHYDHIG 62

Query: 444 GNEDLIKERPGLIVYGGDDRIG-PSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
           G + L+  R        D++I   S+KKL     L + +   S F    + L +  +   
Sbjct: 63  GVDALLSAR--------DEKISIYSKKKLFDRCRLVNESDTLS-FFDGKLSLQVMEVPGH 113

Query: 621 LQKKVTI---QLSSPGDTLFLGGCGQV 692
               V     +L   GDTLF GGCG+V
Sbjct: 114 TLDHVAFYNDELLFCGDTLFSGGCGRV 140


>UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 518

 Score = 41.9 bits (94), Expect = 0.019
 Identities = 19/47 (40%), Positives = 28/47 (59%)
 Frame = +3

Query: 243 GPPVKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE 383
           G  ++ + V  +P   DNY YLIV   T + A VDP +P+ VL+ +E
Sbjct: 154 GSVMRGVAVVPIPIFGDNYAYLIVSMQTHKVAAVDPADPEMVLRIME 200


>UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=4; Proteobacteria|Rep:
           Hydroxyacylglutathione hydrolase precursor -
           Verminephrobacter eiseniae (strain EF01-2)
          Length = 258

 Score = 40.3 bits (90), Expect = 0.057
 Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 1/184 (0%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M++  LPA  DNY++++ D     A +VDP +   V  A+   G+ L             
Sbjct: 1   MNLLALPAFADNYLWMLHD--GHRAIVVDPGQAAPVADALRRLGLQLQAILVTHHHADHV 58

Query: 441 GGNEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
           GG E L +   G  V+G   + +     +L+   ++  +     V   P    G   I+ 
Sbjct: 59  GGVEAL-RNATGASVHGPARESVPEPLVRLAQGDTVDVLGLRLEVIDVPGHTAG--HIAY 115

Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
              +     L   GDTLF GGCG++             +  A      + C HEYTL+ +
Sbjct: 116 YCPQMDGAPLLFCGDTLFSGGCGRLFEGTPAQMLASLDRLAALPGNTLVCCAHEYTLSNL 175

Query: 798 XKFA 809
            KFA
Sbjct: 176 -KFA 178


>UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Trypanosoma brucei|Rep:
           Hydroxyacylglutathione hydrolase, putative - Trypanosoma
           brucei
          Length = 464

 Score = 40.3 bits (90), Expect = 0.057
 Identities = 17/36 (47%), Positives = 22/36 (61%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE 383
           +P L DNY Y I+   TK  A+VDP +P  VL  +E
Sbjct: 137 VPVLLDNYAYFILSCKTKRCAVVDPADPTLVLNMLE 172


>UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas
           aromatica RCB|Rep: Beta-lactamase-like - Dechloromonas
           aromatica (strain RCB)
          Length = 265

 Score = 39.9 bits (89), Expect = 0.075
 Identities = 51/180 (28%), Positives = 75/180 (41%), Gaps = 5/180 (2%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           +++  +PA +DNY++L+     K A +VDP +   VL  +E  G+ L             
Sbjct: 2   LEISFIPAFKDNYIWLLT--RGKRAFVVDPGDAAPVLARLEAGGLMLEGILITHHHADHQ 59

Query: 441 GGNEDLIKERPGLIVYG-GDDRIGPSQKKLSTIQSL----KSVT*MYSVFLHPVIQLGIY 605
           GG  +L K R    VY  G++ I      LS  +S+    + VT M +V  H +  L  Y
Sbjct: 60  GGVAEL-KARWQAEVYAPGNESITGCSCPLSGGESIDVLGQKVTVM-AVPGHTLGHLAYY 117

Query: 606 VIS*LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
               LL           GDTLF  GCG++                A      ++C HEYT
Sbjct: 118 APGALLC----------GDTLFGAGCGRLFEGTPAQMSASLDSIAALPGDTLIYCAHEYT 167


>UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Pasteurellaceae|Rep: Hydroxyacylglutathione hydrolase -
           Mannheimia haemolytica PHL213
          Length = 235

 Score = 39.9 bits (89), Expect = 0.075
 Identities = 34/144 (23%), Positives = 62/144 (43%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           + +  +PAL+DNY++ I  +  ++  I+DP E +  L  + +  +NL             
Sbjct: 2   LQITPIPALKDNYIWAI--RNGQDVIIIDPSEHQPALNFIAKNALNLTAILITHNHHDHT 59

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
            G   ++++ P + VYG  +    +   +S  Q +      Y V    +I+ G +     
Sbjct: 60  DGVSGIVEQYPNIPVYGPQEVAEFANVIVSPEQHISLFG--YDV---RIIESGGHTAG-H 113

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQV 692
           +           GD LF GGCG+V
Sbjct: 114 ISYLFGYDYLFCGDALFSGGCGRV 137


>UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1;
           Methanosphaera stadtmanae DSM 3091|Rep: Predicted
           Zn-dependent hydrolase - Methanosphaera stadtmanae
           (strain DSM 3091)
          Length = 225

 Score = 39.5 bits (88), Expect = 0.099
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG-SLK 700
           +E+N   ++GN  ++ L+TP HT+G +CY+     E    ++FTG     +   +  S  
Sbjct: 119 LENNNVIEVGNWTLKVLYTPGHTSGSVCYY-----EEEKRILFTGDTVYAKGTISDLSYS 173

Query: 701 GTADQMYKALTILSS 745
           G      K+L  L+S
Sbjct: 174 GNYGSYIKSLNTLNS 188


>UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1;
           Geobacter uraniumreducens Rf4|Rep: Beta-lactamase domain
           protein - Geobacter uraniumreducens Rf4
          Length = 233

 Score = 38.7 bits (86), Expect = 0.17
 Identities = 16/44 (36%), Positives = 24/44 (54%)
 Frame = +2

Query: 527 EHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 658
           EH  + ++G   + CL TP HTTG +CY ++      D+V   G
Sbjct: 111 EHLDQIRLGETLINCLLTPGHTTGSMCYLLSHSLFTGDTVFVEG 154


>UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=19; Bacteria|Rep: Hydroxyacylglutathione
           hydrolase, putative - Brucella suis
          Length = 257

 Score = 38.3 bits (85), Expect = 0.23
 Identities = 40/177 (22%), Positives = 68/177 (38%)
 Frame = +3

Query: 255 KNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 434
           + ++++      DNY  LI D  +   A +D  +   +  A+E +G  L           
Sbjct: 3   QRLEIEQFICRSDNYGVLIHDPESALTATIDAPDAYAIEAALERRGWTLDFIFTTHHHLD 62

Query: 435 XAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS 614
              GNE L KE+ G+ + G +           T++     T  + +F   VI    +   
Sbjct: 63  HVEGNEPL-KEKFGVSIIGPEAEKAKIPGIDRTVKGGDEFT--FGLFKVKVISTPGHTAG 119

Query: 615 *LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYT 785
            +       ++   GDTLF  GCG++             +  A      ++CGHEYT
Sbjct: 120 GISYYLPDAKVVFTGDTLFALGCGRLFEGTPATMFHSLEKLVALPGDTALYCGHEYT 176


>UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=1; Plesiocystis pacifica SIR-1|Rep: Probable
           hydroxyacylglutathione hydrolase - Plesiocystis pacifica
           SIR-1
          Length = 270

 Score = 38.3 bits (85), Expect = 0.23
 Identities = 44/146 (30%), Positives = 66/146 (45%), Gaps = 9/146 (6%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           +P   DN+ +L+V +AT EAA +D    + VL+ VE  G+ L             G ++ 
Sbjct: 1   MPFWTDNFTWLLVCEATGEAAAIDGGVAEPVLEYVEAHGLRLTTILTTHTHPDHIGLHKA 60

Query: 456 LIK-ERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLG-----IYVIS* 617
           L K ER G +      R+  S+ +L TI  L        V    V++LG     + +   
Sbjct: 61  LDKAERLGAL------RVVGSRSRLGTIPGLDGPK-GEPVDEGDVVRLGALEGQVMLTEG 113

Query: 618 LLQKKVTI---QLSSPGDTLFLGGCG 686
            +   V+    +L   GDTLF GGCG
Sbjct: 114 HIDGHVSYRFGELLFCGDTLFAGGCG 139


>UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein;
           n=14; Bacteria|Rep: Metallo-beta-lactamase domain
           protein - Synechococcus sp. (strain JA-2-3B'a(2-13))
           (Cyanobacteria bacteriumYellowstone B-Prime)
          Length = 238

 Score = 37.9 bits (84), Expect = 0.30
 Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
 Frame = +3

Query: 270 KILPALQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNL 401
           ++  A    Y YLI D AT+EAA+VDPV  + +  LK + E G+ L
Sbjct: 5   QLFDAETSTYTYLIADPATREAALVDPVLEQVERDLKLIRELGLTL 50


>UniRef50_UPI00006CD5DA Cluster: TNFR/NGFR cysteine-rich region family
            protein; n=1; Tetrahymena thermophila SB210|Rep:
            TNFR/NGFR cysteine-rich region family protein -
            Tetrahymena thermophila SB210
          Length = 2129

 Score = 37.5 bits (83), Expect = 0.40
 Identities = 20/56 (35%), Positives = 26/56 (46%)
 Frame = -2

Query: 682  HPPKKSVSPGEDN*IVTFFWSSYEITYMPSCMTGCKKTLYIQVTDFKLCIVLNFFC 515
            HP  K+      N   T F     I Y  SC+  C K +Y+  T +K CI  NF+C
Sbjct: 1824 HPSCKTCVGPNSNQCQTCF--DLLIKYNSSCIVECPKQMYMTQTPYKQCIECNFYC 1877


>UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Gluconobacter oxydans|Rep: Hydroxyacylglutathione
           hydrolase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 259

 Score = 37.5 bits (83), Expect = 0.40
 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
 Frame = +3

Query: 237 PRGPPVKNMDVKILPALQDNYMYLIVDKATK-EAAIVDPVEPKTVLKAVEEQGVNLXXXX 413
           PRG  V  +D+K +P L DNY +L+   AT+ + A+VDP E   ++  + +  +++    
Sbjct: 17  PRGT-VMPLDIKPIPVLSDNYAWLLT--ATEGQRAVVDPGEAGPIMDEIGDGRLDM-ILL 72

Query: 414 XXXXXXXXAGGNEDLIKERPGLIVYG 491
                   AG   D ++ER G  VYG
Sbjct: 73  THHHADHTAG--TDALRERYGAKVYG 96


>UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;
           Proteobacteria|Rep: Hydroxyacylglutathione hydrolase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 268

 Score = 37.5 bits (83), Expect = 0.40
 Identities = 50/184 (27%), Positives = 71/184 (38%), Gaps = 6/184 (3%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           +PA  DNY++L+ D   ++A  VDP E   V + + E+G  L             GG   
Sbjct: 9   VPAFDDNYIWLVSD--GRDAIAVDPGEAAPVRRVLAERGWRLTAILLTHHHADHVGGVAA 66

Query: 456 LIKERPG---LIVYG-GDDRIGPSQKKLS--TIQSLKSVT*MYSVFLHPVIQLGIYVIS* 617
           L   +P    L VYG   + IG   + LS     +L +    + V   P    G      
Sbjct: 67  LRDSQPDDAPLTVYGPAAEAIGVVTRPLSGGDRVTLDAPAATFDVLDVPGHTRGHIAYFQ 126

Query: 618 LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGI 797
              +         GDTLF  GCG++                A      + C HEYTL+ I
Sbjct: 127 AAGQGNAAPHVFCGDTLFSCGCGRLFEGTPAQMLASLDALAALPGDTHVHCAHEYTLSNI 186

Query: 798 XKFA 809
            +FA
Sbjct: 187 -RFA 189


>UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily protein
           precursor; n=1; Thiomicrospira crunogena XCL-2|Rep:
           Metallo-beta-lactamase superfamily protein precursor -
           Thiomicrospira crunogena (strain XCL-2)
          Length = 268

 Score = 37.5 bits (83), Expect = 0.40
 Identities = 44/181 (24%), Positives = 69/181 (38%), Gaps = 2/181 (1%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKAT--KEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 434
           M +  LP L DNY ++I  +    K A IVDP E + V+   EE  + L           
Sbjct: 1   MKIVGLPTLSDNYTWVIQSENADDKRAWIVDPGESQKVIHYFEENQLQLDGILLTHHHYD 60

Query: 435 XAGGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS 614
              G   ++     + +       GP +     ++    V  +   F   VI+   +   
Sbjct: 61  HTDGIMGVMDALGEVAIVSNAQ--GPFKPVTHPVKEGDQVQVLNETF--QVIETPGHTDE 116

Query: 615 *LLQKKVTIQLSSPGDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAG 794
            +         S  GDTLF GGCG++     +       +  A      ++CGHEYT A 
Sbjct: 117 HICFYHPEALFS--GDTLFTGGCGKIWQNPPEQMAESLLKLRALNDDCMVYCGHEYTYAN 174

Query: 795 I 797
           +
Sbjct: 175 L 175



 Score = 34.7 bits (76), Expect = 2.8
 Identities = 20/82 (24%), Positives = 38/82 (46%)
 Frame = +2

Query: 506 RALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMW 685
           + +T  V+   + ++ N   Q + TP HT  HIC++        D+ +FTGG     ++W
Sbjct: 86  KPVTHPVKEGDQVQVLNETFQVIETPGHTDEHICFYHPEALFSGDT-LFTGG---CGKIW 141

Query: 686 AGSLKGTADQMYKALTILSSCL 751
               +  A+ + K   +   C+
Sbjct: 142 QNPPEQMAESLLKLRALNDDCM 163


>UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including
           glyoxylase; n=2; Magnetospirillum|Rep: Zn-dependent
           hydrolase, including glyoxylase - Magnetospirillum
           magneticum (strain AMB-1 / ATCC 700264)
          Length = 270

 Score = 37.5 bits (83), Expect = 0.40
 Identities = 37/144 (25%), Positives = 58/144 (40%), Gaps = 2/144 (1%)
 Frame = +3

Query: 267 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 446
           V+ +P L DNY+YL  +      A +DP   + VL+ +  +G  L             G 
Sbjct: 19  VEQIPVLSDNYVYLAHEPLGGATAAIDPAVSEPVLERLAARGWTLTHILNTHHHGDHTGA 78

Query: 447 NEDLIKERPGLIVYGG--DDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
           N DL + R G  V G   D    P      T++  +  T M       V+++  +    +
Sbjct: 79  NLDLAR-RTGCAVVGAARDSERIPG----ITLEVSEGETFMLGHAAVTVLEVPGHTSGHV 133

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQV 692
                   +   GDTLF  GCG++
Sbjct: 134 AYWLADSHVLFCGDTLFSLGCGRL 157



 Score = 37.1 bits (82), Expect = 0.53
 Identities = 23/73 (31%), Positives = 36/73 (49%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           +T +V     F +G+  V  L  P HT+GH+ Y++       DS V   G TL       
Sbjct: 103 ITLEVSEGETFMLGHAAVTVLEVPGHTSGHVAYWLA------DSHVLFCGDTLFSLGCGR 156

Query: 692 SLKGTADQMYKAL 730
             +GTA++M+ +L
Sbjct: 157 LFEGTAEEMWASL 169


>UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_7,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 489

 Score = 37.5 bits (83), Expect = 0.40
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           ++K +  N   K+G + +Q L TP HT    C F+   EEG    ++TG    L  +   
Sbjct: 130 ISKVMNDNEFLKVGKVKIQALHTPGHTQESTC-FLLYDEEGKQHSIYTGDTLFLGEVGRP 188

Query: 692 SLKGTAD-QMYKALTILSSCL 751
            L   +D   Y   ++L + L
Sbjct: 189 DLAVKSDVTQYDLASLLYASL 209


>UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of
           metallo-beta-lactamase superfamily; n=1; Clostridium
           acetobutylicum|Rep: Predicted Zn-dependent hydrolase of
           metallo-beta-lactamase superfamily - Clostridium
           acetobutylicum
          Length = 199

 Score = 37.1 bits (82), Expect = 0.53
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = +2

Query: 515 TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 616
           TK V+   + + G L ++C+ TP HT G +CY V
Sbjct: 101 TKYVDDGDELQFGELKIKCIKTPGHTPGGMCYLV 134


>UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Moritella sp. PE36|Rep: Hydroxyacylglutathione hydrolase
           - Moritella sp. PE36
          Length = 258

 Score = 37.1 bits (82), Expect = 0.53
 Identities = 31/145 (21%), Positives = 58/145 (40%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           ++V  +P   DNY++LI +       IVDP +   VL+ + +Q + L             
Sbjct: 2   LEVISIPTFNDNYVWLIKNTENNHCCIVDPGQADPVLQVINQQNLILEAILITHHHYDHI 61

Query: 441 GGNEDLIKERPGLIVYGGDDRIGPSQKKLSTIQSLKSVT*MYSVFLHPVIQLGIYVIS*L 620
            G  D++      +       I      ++ +     +  + +     V+    +    +
Sbjct: 62  DGISDILNASTNPVQVYSSIAI-DVDAPVTLVTENSQLNLLNNSLALTVMATPGHKREHV 120

Query: 621 LQKKVTIQLSSPGDTLFLGGCGQVL 695
           +    T+  S  GDTLF GGCG++L
Sbjct: 121 VYYNQTMLFS--GDTLFSGGCGRLL 143


>UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB;
           n=1; Bdellovibrio bacteriovorus|Rep:
           Hydroxyacylglutathione hydrolase GloB - Bdellovibrio
           bacteriovorus
          Length = 251

 Score = 36.7 bits (81), Expect = 0.70
 Identities = 15/49 (30%), Positives = 29/49 (59%)
 Frame = +3

Query: 255 KNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 401
           K   V+++P   DNY++++ D AT++A  VDP +   V+  +    ++L
Sbjct: 3   KKEHVELVPIFDDNYVFILTDDATQKAVAVDPGDAGPVIDFLRANKLDL 51


>UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily
           protein; n=6; Bacteroidetes|Rep: Metallo-beta-lactamase
           superfamily protein - Porphyromonas gingivalis
           (Bacteroides gingivalis)
          Length = 471

 Score = 36.3 bits (80), Expect = 0.93
 Identities = 16/44 (36%), Positives = 26/44 (59%)
 Frame = +2

Query: 527 EHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 658
           E N  F++GN+ ++ L TP HT    C F+   E G ++ +F+G
Sbjct: 90  EDNQIFELGNVKIRVLHTPGHTMESSC-FLLIDENGREAALFSG 132


>UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1;
           Roseobacter sp. AzwK-3b|Rep: Beta-lactamase-like protein
           - Roseobacter sp. AzwK-3b
          Length = 306

 Score = 36.3 bits (80), Expect = 0.93
 Identities = 16/38 (42%), Positives = 22/38 (57%)
 Frame = +2

Query: 503 DRALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 616
           DR   +  E    FK+GNL+V+ + +P HT G I Y V
Sbjct: 127 DRDFDRLFEDGDTFKLGNLDVRVMLSPGHTLGSITYVV 164


>UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium
           cellulolyticum H10|Rep: Beta-lactamase-like -
           Clostridium cellulolyticum H10
          Length = 235

 Score = 36.3 bits (80), Expect = 0.93
 Identities = 14/45 (31%), Positives = 24/45 (53%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 658
           V+     K+G  +++C+ TP HT G +C+FV       D++   G
Sbjct: 112 VQDGEVIKLGYTDIKCILTPGHTMGGMCFFVDGSLFTGDTIFMEG 156


>UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Clostridium|Rep: Hydroxyacylglutathione hydrolase -
           Clostridium tetani
          Length = 201

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 14/46 (30%), Positives = 28/46 (60%)
 Frame = +2

Query: 521 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 658
           K++    FKIG+  ++C+ TP H+ G +C+ +       ++++FTG
Sbjct: 105 KIKEGDTFKIGDKEIKCIETPGHSLGGMCFLI-------ENIIFTG 143


>UniRef50_Q41EG0 Cluster: Beta-lactamase-like:Rhodanese-like; n=4;
           Bacteria|Rep: Beta-lactamase-like:Rhodanese-like -
           Exiguobacterium sibiricum 255-15
          Length = 468

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 14/52 (26%), Positives = 27/52 (51%)
 Frame = +2

Query: 518 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLL 673
           K V    +FK+GN+  + + TP HT  H+ + +   ++     +FTG +  +
Sbjct: 97  KLVTDGNRFKVGNVTFEVMHTPGHTPEHVSFLLYDRDQTVPMGIFTGDFVFV 148


>UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           unclassified Gammaproteobacteria (miscellaneous)|Rep:
           Hydroxyacylglutathione hydrolase - marine gamma
           proteobacterium HTCC2143
          Length = 258

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 21/65 (32%), Positives = 31/65 (47%)
 Frame = +2

Query: 557 LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYKALTI 736
           + ++ L TP HT  H+C+ V   E+G +  VFTG  TL          G  D +Y+ +  
Sbjct: 104 VQLRVLDTPGHTYAHLCFLVL--EQGIEVAVFTGD-TLFNAGVGHCRSGDVDSLYQTIAE 160

Query: 737 LSSCL 751
              CL
Sbjct: 161 QFHCL 165


>UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein;
           n=14; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Shewanella oneidensis
          Length = 267

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 21/51 (41%), Positives = 26/51 (50%)
 Frame = +3

Query: 657 GDTLFLGGCGQVL*RARQIKCTKH*QF*AAA*PH*MFCGHEYTLAGIXKFA 809
           GDTLF GGCG++        C       A      ++C HEYTLA + KFA
Sbjct: 137 GDTLFSGGCGRLFEGTPAQMCHSLRLLAALPAETRVYCAHEYTLANL-KFA 186


>UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein;
           n=17; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Burkholderia mallei (Pseudomonas mallei)
          Length = 246

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
 Frame = +2

Query: 518 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLL-----RRM 682
           K VE   + ++GN+ ++ L TP HT  HI   VT      +  +   G+TL+     R  
Sbjct: 89  KGVEDGDEIRVGNVVIKVLETPGHTPEHISLLVTDRTRAEEPWLALTGHTLMIGDLGRTE 148

Query: 683 WAGSLKGTADQMYKALTILSS 745
            A S +  A  +++++  L S
Sbjct: 149 LAESAEAGARNLFRSVRTLKS 169


>UniRef50_Q7X477 Cluster: AhlK; n=12; Proteobacteria|Rep: AhlK -
           Klebsiella pneumoniae
          Length = 264

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +2

Query: 551 GNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTL 670
           G+  +QC+FTP H+ GH  + +  P   N ++     YTL
Sbjct: 169 GDGTLQCIFTPGHSPGHQSFLIRLPGGTNFTLAIDAAYTL 208


>UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Beta-lactamase-like -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 464

 Score = 35.5 bits (78), Expect = 1.6
 Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV-VFTG 658
           +     + +GNL ++ L TP HT  H+ + +T    G++ + +FTG
Sbjct: 100 INDGDSWMVGNLKIEVLHTPGHTPEHVIFMLTDTPAGDEPMGIFTG 145


>UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Thiobacillus denitrificans ATCC 25259|Rep:
           Hydroxyacylglutathione hydrolase - Thiobacillus
           denitrificans (strain ATCC 25259)
          Length = 256

 Score = 35.1 bits (77), Expect = 2.1
 Identities = 21/75 (28%), Positives = 36/75 (48%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           LPA +DNY+++  D   K A  VDP +P  +   ++ +G+ L             GGN  
Sbjct: 7   LPAFEDNYIWVWHD--AKYAVAVDPGDPAVLSTYLDSRGLALAAVLVTHHHRDHTGGN-T 63

Query: 456 LIKERPGLIVYGGDD 500
            +++R    +Y  D+
Sbjct: 64  WLRQRYNCAIYAPDN 78


>UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrolase
           (Glyoxalase II) (GLX II) protein; n=1; alpha
           proteobacterium HTCC2255|Rep: Putative
           hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX
           II) protein - alpha proteobacterium HTCC2255
          Length = 255

 Score = 35.1 bits (77), Expect = 2.1
 Identities = 21/69 (30%), Positives = 30/69 (43%)
 Frame = +3

Query: 258 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 437
           ++ V I+P L DNY YLI  + T   A++D  +   +L  + E G  L            
Sbjct: 2   SLSVIIVPCLIDNYAYLIRCEETGHTAVIDVPDAYPILNMINELGWKLNSILITHHHSDH 61

Query: 438 AGGNEDLIK 464
             G E L K
Sbjct: 62  VDGVEQLQK 70


>UniRef50_A1HQX4 Cluster: Beta-lactamase domain protein; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Beta-lactamase
           domain protein - Thermosinus carboxydivorans Nor1
          Length = 332

 Score = 35.1 bits (77), Expect = 2.1
 Identities = 16/49 (32%), Positives = 25/49 (51%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTL 670
           V    +  IG+    C+ TP HT GH+C +     E N  ++F+G + L
Sbjct: 149 VREGYRLVIGDYEFTCITTPGHTPGHVCLY-----EPNRKILFSGDHIL 192


>UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1;
           Encephalitozoon cuniculi|Rep: HYDROXYACYL GLUTATHION
           HYDROLASE - Encephalitozoon cuniculi
          Length = 263

 Score = 35.1 bits (77), Expect = 2.1
 Identities = 10/26 (38%), Positives = 17/26 (65%)
 Frame = +2

Query: 539 KFKIGNLNVQCLFTPCHTTGHICYFV 616
           KF+  ++ ++C  TPCHT    C++V
Sbjct: 124 KFRFKDVEIECFHTPCHTVDSFCFYV 149


>UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2;
           Chloroflexus|Rep: Beta-lactamase-like:Rhodanese-like -
           Chloroflexus aurantiacus J-10-fl
          Length = 466

 Score = 34.7 bits (76), Expect = 2.8
 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV-VFTGGY 664
           V+    + +GN+ VQ + TP HT  HI + +T     +  + VFTG +
Sbjct: 99  VKDGDTWMVGNIKVQVIATPGHTPEHIAFMITDTAGADQPMGVFTGDF 146


>UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein;
           n=1; Lentisphaera araneosa HTCC2155|Rep:
           Metallo-beta-lactamase family protein - Lentisphaera
           araneosa HTCC2155
          Length = 222

 Score = 34.7 bits (76), Expect = 2.8
 Identities = 15/33 (45%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
 Frame = +3

Query: 291 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEE 386
           DN++YLI DK T + A+VDP  +   + +A EE
Sbjct: 13  DNFIYLIKDKKTSDIAVVDPAWDVDAIFRAAEE 45


>UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase related;
           n=4; Thermococcaceae|Rep: Hydroxyacylglutathione
           hydrolase related - Pyrococcus abyssi
          Length = 222

 Score = 34.7 bits (76), Expect = 2.8
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
 Frame = +2

Query: 521 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSL- 697
           K+E   + K+G + ++ + TP HT G  C +    EE  + ++FTG    L       L 
Sbjct: 123 KLEDGDEIKVGKVKLRLIHTPGHTRGSSCLYY---EE--ERIMFTGDTVFLGTYGRTDLP 177

Query: 698 KGTADQMYKALTILSS 745
            G  D++ ++L +L S
Sbjct: 178 TGNEDKIVESLELLKS 193


>UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=10; Chlorobiaceae|Rep:
           Hydroxyacylglutathione hydrolase, putative - Chlorobium
           tepidum
          Length = 215

 Score = 34.3 bits (75), Expect = 3.7
 Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
 Frame = +3

Query: 294 NYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           N+ YL  DKAT EA  VDP   PK ++ A   +G  L              GNE+
Sbjct: 15  NFGYLCADKATGEAFAVDPSNSPKVLVDAAARKGWQLVRAFCTHGHADHTNGNEE 69


>UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=4; Rhodobacteraceae|Rep:
           Hydroxyacylglutathione hydrolase, putative -
           Silicibacter pomeroyi
          Length = 255

 Score = 34.3 bits (75), Expect = 3.7
 Identities = 15/47 (31%), Positives = 26/47 (55%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 401
           +++  +P L DNY YLI D    + A+VD  E   +   ++ +G +L
Sbjct: 3   LEIVTVPCLSDNYAYLIHDADAGKTALVDAPEAAPIQSELDRRGWSL 49


>UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=1; Sodalis glossinidius str. 'morsitans'|Rep: Putative
           hydroxyacylglutathione hydrolase - Sodalis glossinidius
           (strain morsitans)
          Length = 250

 Score = 34.3 bits (75), Expect = 3.7
 Identities = 21/80 (26%), Positives = 40/80 (50%)
 Frame = +3

Query: 261 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 440
           M++  +PAL DNY++L+     +   +VDP +   VL+A+ +  +               
Sbjct: 1   MNLISIPALADNYIWLL-HNDDRRCLVVDPGDATPVLQALADHRLTPVAVLLTHHHQDHV 59

Query: 441 GGNEDLIKERPGLIVYGGDD 500
           GG  +L++  P + VYG ++
Sbjct: 60  GGVSELLQHFP-VPVYGPEE 78


>UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 321

 Score = 34.3 bits (75), Expect = 3.7
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = +2

Query: 503 DRALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 610
           D    K+ ++ T  + G   +  L+ PCHTTGH+ Y
Sbjct: 119 DNPNDKETKNETSIE-GEFQIDFLYVPCHTTGHVLY 153


>UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein;
           n=2; Alteromonadales|Rep: Metallo-beta-lactamase family
           protein - Colwellia psychrerythraea (strain 34H / ATCC
           BAA-681) (Vibriopsychroerythus)
          Length = 265

 Score = 33.9 bits (74), Expect = 4.9
 Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
 Frame = +2

Query: 563 VQCLFT----PCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMYKAL 730
           + C FT    P HT GHI Y+       ND +VF G  TL         +GT  QM+ +L
Sbjct: 110 LDCQFTVLDLPGHTKGHIAYY-------NDKMVFCGD-TLFSGGCGRLFEGTPQQMHHSL 161

Query: 731 TILSSCLT 754
           T L++  T
Sbjct: 162 TKLANLAT 169


>UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep: Beta-lactamase
           domain protein - Clostridium beijerinckii NCIMB 8052
          Length = 224

 Score = 33.9 bits (74), Expect = 4.9
 Identities = 22/94 (23%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLK- 700
           V  + K  IG L + C+ TP HT G +C+ +       ++ +FTG    +R     + K 
Sbjct: 100 VNDSDKISIGKLKMDCVLTPGHTAGGMCFKL-------ENKLFTGDTIFIRGCGICTCKG 152

Query: 701 GTADQMYKALTILSSCLTTLNVLWP*VHFGRNXK 802
           G  ++M++++  +        +++P  +F  + K
Sbjct: 153 GDYNEMFESIKKIKEIAKKNVLIYPGHYFEGDLK 186


>UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2;
           Bacteria|Rep: Beta-lactamase domain protein - Pelobacter
           propionicus (strain DSM 2379)
          Length = 253

 Score = 33.9 bits (74), Expect = 4.9
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +2

Query: 515 TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 613
           TK ++ N    +GN  +Q L TP H+ GH+C++
Sbjct: 130 TKVLKDNDVIDMGNRCIQVLHTPGHSPGHMCFW 162


>UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Magnetococcus sp. MC-1|Rep: Hydroxyacylglutathione
           hydrolase - Magnetococcus sp. (strain MC-1)
          Length = 254

 Score = 33.9 bits (74), Expect = 4.9
 Identities = 22/66 (33%), Positives = 31/66 (46%)
 Frame = +2

Query: 542 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKGTADQMY 721
           F +G   V    TP HT+GH+CY +          +F G  TL         +GT  QM+
Sbjct: 100 FCLGPHQVDTYHTPGHTSGHLCYHIA-------DCLFAGD-TLFSYGCGRLFEGTPQQMW 151

Query: 722 KALTIL 739
           ++L IL
Sbjct: 152 QSLLIL 157


>UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 498

 Score = 33.9 bits (74), Expect = 4.9
 Identities = 17/66 (25%), Positives = 31/66 (46%)
 Frame = +2

Query: 521 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLK 700
           + + N    IG + +Q L+TP HT    C+ +   ++     +FTG    L      +L 
Sbjct: 118 QAKDNEIISIGKIKMQVLYTPGHTNESTCFLLL--DDERQHAIFTGDTLYLEEASFPNLA 175

Query: 701 GTADQM 718
            T++Q+
Sbjct: 176 ATSEQI 181


>UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4;
           Halobacteriaceae|Rep: Beta-lactamase domain protein -
           Halorubrum lacusprofundi ATCC 49239
          Length = 402

 Score = 33.9 bits (74), Expect = 4.9
 Identities = 23/78 (29%), Positives = 36/78 (46%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKG 703
           VE   +F +G+  V+ +FTP HTTG   Y +       DS++ TG    +  +    L+ 
Sbjct: 228 VEDGDEFTVGDATVETVFTPGHTTGMTSYLL------GDSLLATGDGLFIESVARPDLEE 281

Query: 704 TADQMYKALTILSSCLTT 757
             D   +A  +L   L T
Sbjct: 282 GDDGAPEAARMLYDSLQT 299


>UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including
           glyoxylases; n=1; Hahella chejuensis KCTC 2396|Rep:
           Zn-dependent Hydrolase, including glyoxylases - Hahella
           chejuensis (strain KCTC 2396)
          Length = 257

 Score = 33.5 bits (73), Expect = 6.5
 Identities = 21/72 (29%), Positives = 34/72 (47%)
 Frame = +3

Query: 276 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 455
           +PA  DNY++ I      +A +VDP + + VL+ + E  + L             GG  +
Sbjct: 7   IPAFNDNYIWSI-QSDQGDAWVVDPGDAQPVLRHLAENHLTLRGILITHHHHDHTGGVNE 65

Query: 456 LIKERPGLIVYG 491
           L+   P + VYG
Sbjct: 66  LLANHP-VPVYG 76


>UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3;
           Deltaproteobacteria|Rep: Beta-lactamase-like - delta
           proteobacterium MLMS-1
          Length = 213

 Score = 33.5 bits (73), Expect = 6.5
 Identities = 15/38 (39%), Positives = 21/38 (55%)
 Frame = +2

Query: 548 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGG 661
           +G + +Q + TP HT G IC + TAP       +F GG
Sbjct: 118 LGTIELQVIHTPGHTPGGICLY-TAPHLFTGDTLFVGG 154


>UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3;
           Leptospira|Rep: Zn-dependent hydrolase - Leptospira
           borgpetersenii serovar Hardjo-bovis (strain JB197)
          Length = 269

 Score = 33.5 bits (73), Expect = 6.5
 Identities = 18/72 (25%), Positives = 32/72 (44%)
 Frame = +3

Query: 294 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 473
           N+ Y++ +  T E   +DP + + + K ++ +G  L              GN  L+ +R 
Sbjct: 14  NFTYILRNSETSETLSIDPYDSEQIEKFLDSKGWTLDFLLNTHEHEDHTSGNTGLV-QRY 72

Query: 474 GLIVYGGDDRIG 509
           G  VY   + IG
Sbjct: 73  GCTVYSHPEGIG 84


>UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Beta-lactamase-like
           protein - Lentisphaera araneosa HTCC2155
          Length = 213

 Score = 33.5 bits (73), Expect = 6.5
 Identities = 15/52 (28%), Positives = 29/52 (55%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRR 679
           +E +  F+ G   ++ + TP H+ G  C+ +   E  ++ ++F+G  TL RR
Sbjct: 112 IEDSQSFEFGEFKLEAIHTPGHSAGSTCFKI---ENSDEQLLFSGD-TLFRR 159


>UniRef50_Q10428 Cluster: Serine/threonine-protein phosphatase 2A 56
           kDa regulatory subunit delta 1 isoform; n=25;
           Fungi/Metazoa group|Rep: Serine/threonine-protein
           phosphatase 2A 56 kDa regulatory subunit delta 1 isoform
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 548

 Score = 33.5 bits (73), Expect = 6.5
 Identities = 18/63 (28%), Positives = 33/63 (52%)
 Frame = -3

Query: 819 YVSRQIXKFLPKCTHGHKTFSVVRQLLRIVNALYI*SAVPFKEPAHIRLRRVYPPVKTTE 640
           ++ R I     +  + ++ F+ + +LL I+ ++    A+P KE   I L RV  P+   +
Sbjct: 278 FIRRSINNLFLQFVYENEQFNGIAELLEILGSIINGFALPLKEEHKIFLSRVLIPLHKAK 337

Query: 639 SLP 631
           SLP
Sbjct: 338 SLP 340


>UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=4; cellular organisms|Rep:
           Hydroxyacylglutathione hydrolase, putative - Caulobacter
           crescentus (Caulobacter vibrioides)
          Length = 249

 Score = 33.1 bits (72), Expect = 8.6
 Identities = 20/73 (27%), Positives = 35/73 (47%)
 Frame = +2

Query: 512 LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAG 691
           L + V    +  +G+  +  + T  HT GH+ Y+     +  D++ F G  TL       
Sbjct: 88  LDRVVRDGEEVMLGDTRLTVIDTGGHTLGHVSYY-----DAEDAIAFVGD-TLFALGCGR 141

Query: 692 SLKGTADQMYKAL 730
             +GTA+QM+ +L
Sbjct: 142 LFEGTAEQMWDSL 154


>UniRef50_Q1ARM7 Cluster: Beta-lactamase-like protein; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep:
           Beta-lactamase-like protein - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 266

 Score = 33.1 bits (72), Expect = 8.6
 Identities = 17/44 (38%), Positives = 25/44 (56%)
 Frame = +2

Query: 503 DRALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 634
           +R L ++++ + +   G   V  LFTP HT GH+ Y V  PE G
Sbjct: 155 ERILWRELDGDAELAPG---VWALFTPGHTPGHMSYRVDLPESG 195


>UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1;
           Alkaliphilus metalliredigens QYMF|Rep: Beta-lactamase
           domain protein - Alkaliphilus metalliredigens QYMF
          Length = 207

 Score = 33.1 bits (72), Expect = 8.6
 Identities = 18/67 (26%), Positives = 30/67 (44%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGGYTLLRRMWAGSLKG 703
           + H     +G L ++ + TP HT G IC  V      ++ V+FTG       +    L G
Sbjct: 110 LSHGDTISVGALQLEVIHTPGHTPGSICLAVK-----DEKVIFTGDTVFSDALGRTDLAG 164

Query: 704 TADQMYK 724
            ++ M +
Sbjct: 165 GSEAMLR 171


>UniRef50_A1U0H3 Cluster: Beta-lactamase domain protein; n=1;
           Marinobacter aquaeolei VT8|Rep: Beta-lactamase domain
           protein - Marinobacter aquaeolei (strain ATCC 700491 /
           DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus
           (strain DSM 11845))
          Length = 186

 Score = 33.1 bits (72), Expect = 8.6
 Identities = 13/29 (44%), Positives = 17/29 (58%)
 Frame = +2

Query: 524 VEHNTKFKIGNLNVQCLFTPCHTTGHICY 610
           VE    F++G L+ Q + TP HT GH  Y
Sbjct: 92  VEEGRPFQVGRLSFQPIHTPGHTDGHFAY 120


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 757,022,057
Number of Sequences: 1657284
Number of extensions: 14356677
Number of successful extensions: 33827
Number of sequences better than 10.0: 115
Number of HSP's better than 10.0 without gapping: 32408
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33706
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 70914189703
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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