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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmov10a15
         (676 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide ...   141   1e-32
UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA ...   139   7e-32
UniRef50_Q5VVL7 Cluster: Dihydrolipoamide branched chain transac...   128   9e-29
UniRef50_P11182 Cluster: Lipoamide acyltransferase component of ...   128   9e-29
UniRef50_UPI000155CECB Cluster: PREDICTED: similar to transacyla...   127   3e-28
UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide ...   122   6e-27
UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacyla...   121   1e-26
UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila melanog...   112   9e-24
UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1; ...   110   3e-23
UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of ...   107   2e-22
UniRef50_UPI0001555D03 Cluster: PREDICTED: similar to 2-oxogluta...   106   4e-22
UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1; ...   106   4e-22
UniRef50_Q7SH25 Cluster: Putative uncharacterized protein NCU027...   101   2e-20
UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex su...   100   3e-20
UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain transac...   100   4e-20
UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1; Dictyo...   100   4e-20
UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2; ...    96   6e-19
UniRef50_Q4P9L5 Cluster: Putative uncharacterized protein; n=1; ...    92   1e-17
UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9; Eur...    89   1e-16
UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain transac...    83   5e-15
UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8; Plas...    83   6e-15
UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, wh...    83   8e-15
UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid dehydrog...    79   7e-14
UniRef50_Q5KP05 Cluster: Tricarboxylic acid cycle-related protei...    79   7e-14
UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex,...    75   1e-12
UniRef50_A6TMP1 Cluster: Catalytic domain of components of vario...    72   1e-11
UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase, p...    72   1e-11
UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransfera...    71   3e-11
UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E...    69   8e-11
UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2 comp...    69   8e-11
UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase co...    68   2e-10
UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu...    67   4e-10
UniRef50_UPI00006D8691 Cluster: COG0508: Pyruvate/2-oxoglutarate...    66   6e-10
UniRef50_Q15U82 Cluster: Catalytic domain of components of vario...    66   1e-09
UniRef50_P09062 Cluster: Lipoamide acyltransferase component of ...    66   1e-09
UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue acetyltrans...    65   1e-09
UniRef50_A0JUQ7 Cluster: Catalytic domain of components of vario...    65   2e-09
UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of ...    65   2e-09
UniRef50_A4BTC4 Cluster: Dihydrolipoamide acetyltransferase; n=2...    64   3e-09
UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 compon...    64   3e-09
UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;...    63   5e-09
UniRef50_A0K281 Cluster: Catalytic domain of components of vario...    63   5e-09
UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci...    63   7e-09
UniRef50_Q1GTH9 Cluster: Catalytic domain of components of vario...    63   7e-09
UniRef50_A0LQU7 Cluster: Catalytic domain of components of vario...    62   9e-09
UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8; My...    62   1e-08
UniRef50_A1RJV4 Cluster: Catalytic domain of components of vario...    62   1e-08
UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2; Actinom...    62   1e-08
UniRef50_A6PJ30 Cluster: Catalytic domain of components of vario...    61   2e-08
UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2...    61   2e-08
UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of ...    61   3e-08
UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase co...    61   3e-08
UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of p...    60   4e-08
UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid...    60   5e-08
UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2 compo...    60   6e-08
UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 / dihydrolipo...    60   6e-08
UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase comp...    60   6e-08
UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep: ...    59   8e-08
UniRef50_A3JES0 Cluster: 2-oxoglutarate dehydrogenase E2; n=1; M...    59   8e-08
UniRef50_A0JY25 Cluster: Biotin/lipoyl attachment domain-contain...    59   8e-08
UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3; Cystoba...    59   1e-07
UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic doma...    58   1e-07
UniRef50_Q83DQ8 Cluster: Dehydrogenase, E2 component, acyltransf...    58   2e-07
UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1; Symbiob...    58   2e-07
UniRef50_A0JZU9 Cluster: Catalytic domain of components of vario...    58   2e-07
UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2...    58   3e-07
UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid dehydrog...    57   3e-07
UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp....    57   3e-07
UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2 compo...    56   6e-07
UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2, dihy...    56   6e-07
UniRef50_A6FIQ1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    56   8e-07
UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni...    56   8e-07
UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2 compon...    56   8e-07
UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue acetyltrans...    56   8e-07
UniRef50_P37942 Cluster: Lipoamide acyltransferase component of ...    56   1e-06
UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase comp...    55   1e-06
UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1; Pyrobac...    55   2e-06
UniRef50_UPI00005103B2 Cluster: COG0508: Pyruvate/2-oxoglutarate...    54   2e-06
UniRef50_UPI000038E473 Cluster: hypothetical protein Faci_030003...    54   2e-06
UniRef50_Q5ZV80 Cluster: Dihydrolipoamide acetyltransferase; n=5...    54   2e-06
UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue ac...    54   2e-06
UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase comp...    54   3e-06
UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep...    54   4e-06
UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic doma...    54   4e-06
UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex dihydrol...    54   4e-06
UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue succinyltra...    53   6e-06
UniRef50_Q8PQ85 Cluster: Dihydrolipoamide acyltransferase; n=7; ...    53   7e-06
UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n...    53   7e-06
UniRef50_A4WK39 Cluster: Catalytic domain of components of vario...    53   7e-06
UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue acetyltrans...    53   7e-06
UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4; Bacilla...    52   1e-05
UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransfera...    52   1e-05
UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4; Actinomycet...    52   1e-05
UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n...    52   1e-05
UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue succinyltra...    52   1e-05
UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E...    51   2e-05
UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, ...    51   2e-05
UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of ...    51   2e-05
UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue succinyltra...    51   3e-05
UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1; Bdellov...    50   4e-05
UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2 com...    50   4e-05
UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3; ...    50   4e-05
UniRef50_Q7NLM9 Cluster: Gll1092 protein; n=1; Gloeobacter viola...    50   5e-05
UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component dih...    50   5e-05
UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme comp...    50   5e-05
UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2 compon...    50   5e-05
UniRef50_Q5BXT9 Cluster: SJCHGC06137 protein; n=1; Schistosoma j...    50   5e-05
UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase co...    50   7e-05
UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2 comp...    50   7e-05
UniRef50_Q2UDD6 Cluster: Predicted protein; n=1; Aspergillus ory...    50   7e-05
UniRef50_O94709 Cluster: Probable pyruvate dehydrogenase protein...    50   7e-05
UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1; ...    49   9e-05
UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferas...    49   1e-04
UniRef50_Q7X2B2 Cluster: PdhC; n=1; Lactobacillus reuteri|Rep: P...    49   1e-04
UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    49   1e-04
UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue acetyltrans...    49   1e-04
UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue acetyltrans...    49   1e-04
UniRef50_A1UIB1 Cluster: Catalytic domain of components of vario...    48   2e-04
UniRef50_A1FTV4 Cluster: Catalytic domain of components of vario...    48   2e-04
UniRef50_A0XBY6 Cluster: Biotin/lipoyl attachment domain-contain...    48   2e-04
UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;...    48   2e-04
UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1; ...    48   2e-04
UniRef50_Q7N5R0 Cluster: Similarities with dihydrolipoamide acyl...    48   2e-04
UniRef50_A5UTW4 Cluster: Catalytic domain of components of vario...    48   2e-04
UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue succinyltra...    48   2e-04
UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X compon...    48   2e-04
UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue acetyltrans...    48   2e-04
UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex d...    48   3e-04
UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of ...    48   3e-04
UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component dih...    48   3e-04
UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 compone...    48   3e-04
UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3 compo...    48   3e-04
UniRef50_Q59RQ7 Cluster: Putative uncharacterized protein; n=1; ...    48   3e-04
UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue succinyltra...    48   3e-04
UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n...    47   4e-04
UniRef50_A1SQB9 Cluster: Catalytic domain of components of vario...    47   4e-04
UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n...    47   5e-04
UniRef50_A6Q9K5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    47   5e-04
UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    47   5e-04
UniRef50_A6PBA2 Cluster: Catalytic domain of components of vario...    47   5e-04
UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component, d...    47   5e-04
UniRef50_Q38C09 Cluster: Dihydrolipoamide acetyltransferase, put...    47   5e-04
UniRef50_A6UDY3 Cluster: Biotin/lipoyl attachment domain-contain...    46   6e-04
UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue succinyltra...    46   6e-04
UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to ENSANGP000...    46   8e-04
UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep: M...    46   8e-04
UniRef50_A1UBW5 Cluster: Catalytic domain of components of vario...    46   8e-04
UniRef50_Q6CF67 Cluster: Yarrowia lipolytica chromosome B of str...    46   8e-04
UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue acetyltrans...    46   8e-04
UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue succinyltra...    46   8e-04
UniRef50_Q8D6Q5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    46   0.001
UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1; Streptom...    45   0.001
UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu...    45   0.001
UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1...    45   0.001
UniRef50_A0LLM2 Cluster: Catalytic domain of components of vario...    45   0.001
UniRef50_A0JS87 Cluster: Catalytic domain of components of vario...    45   0.001
UniRef50_Q830B2 Cluster: Acetyl-CoA carboxylase, biotin carboxyl...    45   0.002
UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7; ro...    45   0.002
UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2 compo...    45   0.002
UniRef50_Q4AFR6 Cluster: Biotin/lipoyl attachment; n=1; Chlorobi...    44   0.003
UniRef50_Q4AFC2 Cluster: Biotin/lipoyl attachment; n=1; Chlorobi...    44   0.003
UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni...    44   0.003
UniRef50_Q4QCG0 Cluster: Dihydrolipoamide acetyltransferaselike ...    44   0.003
UniRef50_Q7RWS2 Cluster: Putative uncharacterized protein NCU000...    44   0.003
UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase c...    44   0.003
UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2 compon...    44   0.003
UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex dihydrol...    44   0.003
UniRef50_Q9SXV7 Cluster: Dihydrolipoamide acetyltransferase; n=1...    44   0.003
UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue succinyltra...    44   0.003
UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue succinyltra...    44   0.003
UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase; ...    44   0.004
UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;...    44   0.004
UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;...    44   0.004
UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2 compon...    44   0.004
UniRef50_A1SJ23 Cluster: Catalytic domain of components of vario...    44   0.004
UniRef50_A0LSF1 Cluster: Catalytic domain of components of vario...    44   0.004
UniRef50_A0G738 Cluster: Catalytic domain of components of vario...    44   0.004
UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;...    44   0.004
UniRef50_A5ZAG1 Cluster: Putative uncharacterized protein; n=1; ...    43   0.006
UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransfera...    43   0.006
UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;...    43   0.006
UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue acetyltrans...    43   0.006
UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate d...    43   0.008
UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).; ...    43   0.008
UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome s...    43   0.008
UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1...    43   0.008
UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3...    43   0.008
UniRef50_A6Q3I4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    43   0.008
UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue succinyltra...    43   0.008
UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2 compon...    43   0.008
UniRef50_Q6CNU8 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    43   0.008
UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid dehydrog...    42   0.010
UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    42   0.010
UniRef50_Q4DYI5 Cluster: Dihydrolipoamide acetyltransferase, put...    42   0.010
UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue acetyltrans...    42   0.010
UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n...    42   0.014
UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransfer...    42   0.014
UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue acetyltrans...    42   0.014
UniRef50_A1W7R7 Cluster: Dihydrolipoamide dehydrogenase; n=58; B...    42   0.014
UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit...    42   0.014
UniRef50_A4L2T6 Cluster: AccB; n=2; Lactobacillus reuteri|Rep: A...    42   0.018
UniRef50_A4FIZ9 Cluster: Acetoin dehydrogenase, dihydrolipoamide...    42   0.018
UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2 compon...    42   0.018
UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransfera...    41   0.024
UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacte...    41   0.024
UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of ...    41   0.024
UniRef50_A0G901 Cluster: Biotin/lipoyl attachment; n=1; Burkhold...    41   0.024
UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, who...    41   0.024
UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue succinyltra...    41   0.024
UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue succinyltra...    41   0.024
UniRef50_UPI00015552BA Cluster: PREDICTED: similar to dihydrolip...    41   0.032
UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate d...    41   0.032
UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2 compon...    41   0.032
UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1; ...    41   0.032
UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,...    40   0.042
UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;...    40   0.042
UniRef50_Q0A5F2 Cluster: Catalytic domain of components of vario...    40   0.042
UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;...    40   0.042
UniRef50_A7AMV7 Cluster: Biotin-requiring enzyme family protein;...    40   0.042
UniRef50_Q74Z83 Cluster: AGR323Cp; n=1; Eremothecium gossypii|Re...    40   0.042
UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex, dihydro...    40   0.055
UniRef50_Q12FH2 Cluster: Catalytic domain of components of vario...    40   0.055
UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue acetyltrans...    40   0.055
UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase homo...    40   0.073
UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3...    40   0.073
UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of ...    40   0.073
UniRef50_A1SN86 Cluster: Biotin/lipoyl attachment domain-contain...    40   0.073
UniRef50_A1R7P9 Cluster: Biotin / lipoyl attachment domain prote...    40   0.073
UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue acetyltrans...    40   0.073
UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci...    39   0.096
UniRef50_Q057U1 Cluster: Pyruvate dehydrogenase E2 component; n=...    39   0.096
UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella ve...    39   0.096
UniRef50_P16451 Cluster: Pyruvate dehydrogenase complex protein ...    39   0.096
UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component sub...    39   0.096
UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase comp...    39   0.13 
UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=4...    39   0.13 
UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic doma...    39   0.13 
UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1...    39   0.13 
UniRef50_Q1AT73 Cluster: Catalytic domain of components of vario...    39   0.13 
UniRef50_A6X6G3 Cluster: Biotin/lipoyl attachment domain protein...    39   0.13 
UniRef50_A4SZ52 Cluster: Catalytic domain of components of vario...    39   0.13 
UniRef50_A2VX19 Cluster: Pyruvate dehydrogenase complex, dehydro...    39   0.13 
UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue acetyltrans...    39   0.13 
UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;...    38   0.17 
UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 compone...    38   0.17 
UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1...    38   0.17 
UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2; ...    38   0.17 
UniRef50_Q97Y20 Cluster: Dihydrolipoamide S-acetyltransferase, a...    38   0.17 
UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue succinyltra...    38   0.17 
UniRef50_Q59695 Cluster: Dihydrolipoyllysine-residue acetyltrans...    38   0.17 
UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (...    38   0.22 
UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue acetyltrans...    38   0.22 
UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue succinyltra...    38   0.22 
UniRef50_A0NRH6 Cluster: 2-oxo acid dehydrogenases acyltransfera...    38   0.22 
UniRef50_Q89AQ9 Cluster: Dihydrolipoyllysine-residue acetyltrans...    38   0.22 
UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue succinyltra...    38   0.22 
UniRef50_Q7BKG0 Cluster: Predicted biotin carboxyl carrier prote...    38   0.29 
UniRef50_Q1V1J3 Cluster: Dihydrolipoamide S-acetyltransferase; n...    38   0.29 
UniRef50_Q1M9D5 Cluster: Putative biotin-binding protein; n=1; R...    38   0.29 
UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue acetyltrans...    38   0.29 
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n...    37   0.39 
UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2 comp...    37   0.39 
UniRef50_Q53594 Cluster: E2 branched-chain alpha keto acid dehyd...    37   0.39 
UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1...    37   0.39 
UniRef50_A3UCP2 Cluster: Dihydrolipoamide acetyltransferase; n=1...    37   0.39 
UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; ...    37   0.39 
UniRef50_Q5BY55 Cluster: SJCHGC04170 protein; n=1; Schistosoma j...    37   0.39 
UniRef50_Q4PHZ8 Cluster: Putative uncharacterized protein; n=1; ...    37   0.39 
UniRef50_A7TK36 Cluster: Putative uncharacterized protein; n=1; ...    37   0.39 
UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia gloss...    37   0.51 
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    37   0.51 
UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase...    37   0.51 
UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, lon...    37   0.51 
UniRef50_A6W003 Cluster: Catalytic domain of components of vario...    37   0.51 
UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue acetyltrans...    37   0.51 
UniRef50_Q8U4T3 Cluster: 2-oxo acid dehydrogenase lipoyl domain;...    37   0.51 
UniRef50_Q04DN3 Cluster: Biotin carboxyl carrier protein; n=1; O...    36   0.68 
UniRef50_A4RM31 Cluster: Putative uncharacterized protein; n=1; ...    36   0.68 
UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component, di...    36   0.90 
UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n...    36   0.90 
UniRef50_A5V4B2 Cluster: Catalytic domain of components of vario...    36   0.90 
UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransfera...    36   0.90 
UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue acetyltrans...    36   0.90 
UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    36   1.2  
UniRef50_Q899N8 Cluster: Biotin carboxyl carrier protein of acet...    36   1.2  
UniRef50_Q5NZW1 Cluster: Biotin carboxyl carrier subunit of acet...    36   1.2  
UniRef50_Q1IUH9 Cluster: Carbamoyl-phosphate synthase L chain, A...    36   1.2  
UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2 com...    36   1.2  
UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=...    36   1.2  
UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex dihydrol...    36   1.2  
UniRef50_Q7RFX9 Cluster: Putative dihydrolipoamide S-acetyltrans...    36   1.2  
UniRef50_Q5VGY2 Cluster: Dihydrolipoamide S-acetyltransferase; n...    36   1.2  
UniRef50_A5KCF0 Cluster: Dihydrolipoamide acetyltransferase, put...    36   1.2  
UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue acetyltrans...    36   1.2  
UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue acetyltrans...    36   1.2  
UniRef50_UPI00006DB259 Cluster: COG0508: Pyruvate/2-oxoglutarate...    35   1.6  
UniRef50_Q8F3R1 Cluster: Biotin_lipoyl domain protein; n=4; Lept...    35   1.6  
UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue succinyltra...    35   1.6  
UniRef50_A4XEQ9 Cluster: Catalytic domain of components of vario...    35   1.6  
UniRef50_A1WK19 Cluster: Alpha/beta hydrolase fold; n=1; Vermine...    35   1.6  
UniRef50_Q10B57 Cluster: Retrotransposon protein, putative, uncl...    35   1.6  
UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase, put...    35   1.6  
UniRef50_Q83C43 Cluster: Conserved domain protein; n=2; Coxiella...    35   2.1  
UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2 comp...    35   2.1  
UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoam...    35   2.1  
UniRef50_A1AXV6 Cluster: Acetyl-CoA carboxylase, biotin carboxyl...    35   2.1  
UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue acetyltrans...    35   2.1  
UniRef50_Q96RQ3 Cluster: Methylcrotonoyl-CoA carboxylase subunit...    35   2.1  
UniRef50_Q7VDH5 Cluster: Dihydrolipoamide S-acetyltransferase; n...    34   2.7  
UniRef50_Q187Q0 Cluster: Biotin carboxyl carrier protein of acet...    34   2.7  
UniRef50_A4F1Y4 Cluster: Dihydrolopoamide acyltransferase; n=1; ...    34   2.7  
UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2 compon...    34   2.7  
UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase; n...    34   2.7  
UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n...    34   2.7  
UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue acetyltrans...    34   2.7  
UniRef50_Q6ZBH9 Cluster: Probable protein NAP1; n=6; Magnoliophy...    34   2.7  
UniRef50_A6S7Q2 Cluster: Predicted protein; n=2; Sclerotiniaceae...    27   3.2  
UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;...    34   3.6  
UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase comp...    34   3.6  
UniRef50_Q1PVI6 Cluster: Putative uncharacterized protein; n=1; ...    34   3.6  
UniRef50_O66382 Cluster: Esterase2; n=2; Acetobacteraceae|Rep: E...    34   3.6  
UniRef50_A3VIE9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    34   3.6  
UniRef50_UPI0000509C9C Cluster: hypothetical protein LOC549074; ...    33   4.8  
UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n...    33   4.8  
UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases acyl...    33   4.8  
UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2 comp...    33   4.8  
UniRef50_A6LSC7 Cluster: Acetyl-CoA carboxylase, biotin carboxyl...    33   4.8  
UniRef50_A6GQ97 Cluster: Dihydrolipoamide acetyltransferase (E2)...    33   4.8  
UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole gen...    33   4.8  
UniRef50_P29539 Cluster: Protein RIF1; n=2; Saccharomyces cerevi...    33   4.8  
UniRef50_UPI00006CB9E3 Cluster: hypothetical protein TTHERM_0055...    33   6.3  
UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component, dih...    33   6.3  
UniRef50_Q39FN4 Cluster: Alpha/beta hydrolase; n=10; Burkholderi...    33   6.3  
UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue acetyltrans...    33   6.3  
UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7...    33   6.3  
UniRef50_A7GYF7 Cluster: MacA; n=3; Campylobacter|Rep: MacA - Ca...    33   6.3  
UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue succinyltra...    33   6.3  
UniRef50_A6TX89 Cluster: Efflux transporter, RND family, MFP sub...    33   6.3  
UniRef50_A6GLP0 Cluster: Probable acyl-coa carboxylase alpha cha...    33   6.3  
UniRef50_A5I7X2 Cluster: Biotin carboxyl carrier protein of acet...    33   6.3  
UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue acetyltrans...    33   6.3  
UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue su...    33   6.3  
UniRef50_Q7CNS6 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP...    33   8.4  
UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=...    33   8.4  
UniRef50_Q4EDM9 Cluster: Putative uncharacterized protein; n=1; ...    33   8.4  
UniRef50_Q1WUR9 Cluster: Biotin carboxyl carrier protein of acet...    33   8.4  
UniRef50_Q1Q3X0 Cluster: Putative uncharacterized protein; n=1; ...    33   8.4  
UniRef50_Q1EYD1 Cluster: Acetyl-CoA biotin carboxyl carrier; n=1...    33   8.4  
UniRef50_Q15Y91 Cluster: Efflux transporter, RND family, MFP sub...    33   8.4  
UniRef50_A6BCV2 Cluster: Putative uncharacterized protein; n=2; ...    33   8.4  
UniRef50_A4M1P4 Cluster: Biotin/lipoyl attachment domain-contain...    33   8.4  
UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza sativa...    33   8.4  
UniRef50_A3CFJ5 Cluster: Putative uncharacterized protein; n=2; ...    33   8.4  

>UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide
           acyltransferase component of branched-chain alpha-keto
           acid dehydrogenase complex, mitochondrial precursor
           (Dihydrolipoyllysine-residue
           (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
           branched chain transacylase) (BCKAD ...; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Lipoamide
           acyltransferase component of branched-chain alpha-keto
           acid dehydrogenase complex, mitochondrial precursor
           (Dihydrolipoyllysine-residue
           (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
           branched chain transacylase) (BCKAD ... - Tribolium
           castaneum
          Length = 429

 Score =  141 bits (342), Expect = 1e-32
 Identities = 66/109 (60%), Positives = 81/109 (74%)
 Frame = +2

Query: 350 LRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 529
           L++FH+  +    V+FKLSDIGEGIREV +KEWFVKVGD V QFD ICEVQSDKA+VTIT
Sbjct: 23  LKNFHSCASYAAQVSFKLSDIGEGIREVTVKEWFVKVGDKVSQFDEICEVQSDKASVTIT 82

Query: 530 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
           SRYDG+I +L++ ID+ A VG+PLVDI+ +  E    PT     KP  E
Sbjct: 83  SRYDGVIKKLHYKIDEIASVGKPLVDIETEGDEPSAAPTPEEESKPPVE 131


>UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 462

 Score =  139 bits (336), Expect = 7e-32
 Identities = 63/99 (63%), Positives = 81/99 (81%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R  H + +++K V+F LSDIGEGIREV +KEWFVK GD V+QFDN+CEVQSDKA+VTITS
Sbjct: 27  RCLHVTSSLDKTVSFNLSDIGEGIREVTVKEWFVKEGDTVEQFDNLCEVQSDKASVTITS 86

Query: 533 RYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTD 649
           RYDG IT+++H ID+ ALVG+PL+D DV + + D +P D
Sbjct: 87  RYDGKITKIHHKIDEIALVGKPLLDFDVVNEDED-EPED 124


>UniRef50_Q5VVL7 Cluster: Dihydrolipoamide branched chain
           transacylase E2; n=8; Euteleostomi|Rep: Dihydrolipoamide
           branched chain transacylase E2 - Homo sapiens (Human)
          Length = 320

 Score =  128 bits (310), Expect = 9e-29
 Identities = 59/87 (67%), Positives = 74/87 (85%), Gaps = 3/87 (3%)
 Frame = +2

Query: 383 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 562
           ++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 63  QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 122

Query: 563 HDIDQTALVGQPLVDID---VQDSEND 634
           +++D  A VG+PLVDI+   ++DSE D
Sbjct: 123 YNLDDIAYVGKPLVDIETEALKDSEED 149


>UniRef50_P11182 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-keto acid dehydrogenase complex,
           mitochondrial precursor (EC 2.3.1.168)
           (Dihydrolipoyllysine-residue
           (2-methylpropanoyl)transferase); n=29; Eumetazoa|Rep:
           Lipoamide acyltransferase component of branched-chain
           alpha-keto acid dehydrogenase complex, mitochondrial
           precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue
           (2-methylpropanoyl)transferase) - Homo sapiens (Human)
          Length = 482

 Score =  128 bits (310), Expect = 9e-29
 Identities = 59/87 (67%), Positives = 74/87 (85%), Gaps = 3/87 (3%)
 Frame = +2

Query: 383 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 562
           ++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 63  QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 122

Query: 563 HDIDQTALVGQPLVDID---VQDSEND 634
           +++D  A VG+PLVDI+   ++DSE D
Sbjct: 123 YNLDDIAYVGKPLVDIETEALKDSEED 149


>UniRef50_UPI000155CECB Cluster: PREDICTED: similar to transacylase;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           transacylase - Ornithorhynchus anatinus
          Length = 325

 Score =  127 bits (306), Expect = 3e-28
 Identities = 65/103 (63%), Positives = 82/103 (79%), Gaps = 4/103 (3%)
 Frame = +2

Query: 338 LSKELRHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKA 514
           LS   R   T+ AV+ +IV FKLSDIGEGI EV +KEW+VK GD V QFD+ICEVQSDKA
Sbjct: 177 LSLPRRLLRTTAAVDGQIVQFKLSDIGEGITEVTVKEWYVKEGDTVSQFDSICEVQSDKA 236

Query: 515 AVTITSRYDGIITRLYHDIDQTALVGQPLVDID---VQDSEND 634
           +VTITSRYDGII +L++++++TA VG+PLVDI+   V+ SE D
Sbjct: 237 SVTITSRYDGIIRKLHYNVEETANVGKPLVDIETEAVKASEED 279


>UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide
           acyltransferase component of branched-chain alpha-keto
           acid dehydrogenase complex, mitochondrial precursor
           (Dihydrolipoyllysine-residue
           (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
           branched chain transacylase) (BCKAD ...; n=2;
           Apocrita|Rep: PREDICTED: similar to Lipoamide
           acyltransferase component of branched-chain alpha-keto
           acid dehydrogenase complex, mitochondrial precursor
           (Dihydrolipoyllysine-residue
           (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
           branched chain transacylase) (BCKAD ... - Apis mellifera
          Length = 501

 Score =  122 bits (295), Expect = 6e-27
 Identities = 57/102 (55%), Positives = 74/102 (72%), Gaps = 1/102 (0%)
 Frame = +2

Query: 344 KELRHFHTSH-AVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAV 520
           ++ R F  S+     +V FKLSDIGEGIR+V IKEW+VK GD V QFDNICEVQSDKA+V
Sbjct: 92  QKCRFFSVSYFRYGTVVPFKLSDIGEGIRDVTIKEWYVKPGDRVSQFDNICEVQSDKASV 151

Query: 521 TITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPT 646
           TITSRYDG+I  L++ +D   L+G  L+DI++ D +   + T
Sbjct: 152 TITSRYDGLIKALHYKVDDIVLIGNSLLDIELDDDKQQQQQT 193


>UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacylase;
           n=2; Deuterostomia|Rep: PREDICTED: similar to
           transacylase - Strongylocentrotus purpuratus
          Length = 620

 Score =  121 bits (292), Expect = 1e-26
 Identities = 52/84 (61%), Positives = 72/84 (85%)
 Frame = +2

Query: 365 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 544
           +S +  ++V FKLSDIGEGI EVV+KEW+V  GD V QFD+ICEVQSDKA+VTITSR+DG
Sbjct: 80  SSRSCGEVVQFKLSDIGEGIMEVVVKEWYVSEGDTVAQFDSICEVQSDKASVTITSRFDG 139

Query: 545 IITRLYHDIDQTALVGQPLVDIDV 616
           ++ +L++++++TA VG PLVDI++
Sbjct: 140 VVKKLHYELEETANVGMPLVDIEL 163


>UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila
           melanogaster CG5599 protein; n=1; Yarrowia
           lipolytica|Rep: Similar to tr|Q9VXY3 Drosophila
           melanogaster CG5599 protein - Yarrowia lipolytica
           (Candida lipolytica)
          Length = 466

 Score =  112 bits (269), Expect = 9e-24
 Identities = 54/112 (48%), Positives = 72/112 (64%), Gaps = 5/112 (4%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R  H  H    ++ FKL+DIGEGI+E  + +WFV+ G  + +FD ICEVQSDKA+V ITS
Sbjct: 24  RALHACHIARAVIPFKLADIGEGIKECEVIQWFVEPGARINEFDQICEVQSDKASVEITS 83

Query: 533 RYDGIITRLYHDIDQTALVGQPLVDIDVQD-----SENDGKPTDVAPDKPVA 673
           RY G+I +L++D    ALVG+PLVDID  +     SE   + +D AP    A
Sbjct: 84  RYTGVIKKLHYDAGDMALVGKPLVDIDTGEGGEGASEVAAESSDAAPSTAAA 135


>UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 490

 Score =  110 bits (265), Expect = 3e-23
 Identities = 52/97 (53%), Positives = 69/97 (71%)
 Frame = +2

Query: 329 NESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSD 508
           N  +  + R FH S  +  +  + L+DIGEGI E  + +WFVK G  V+QFD ICEVQSD
Sbjct: 30  NICIQGQRRAFHGSQRLLVVKPYLLADIGEGITECQVIQWFVKPGARVEQFDPICEVQSD 89

Query: 509 KAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQ 619
           KA+V ITSR+DG+I +LY++ D  A VG+PLVDID+Q
Sbjct: 90  KASVEITSRFDGVIKKLYYEPDDMAKVGKPLVDIDIQ 126


>UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-keto acid dehydrogenase complex,
           mitochondrial, putative; n=1; Babesia bovis|Rep:
           Lipoamide acyltransferase component of branched-chain
           alpha-keto acid dehydrogenase complex, mitochondrial,
           putative - Babesia bovis
          Length = 417

 Score =  107 bits (258), Expect = 2e-22
 Identities = 54/113 (47%), Positives = 72/113 (63%), Gaps = 5/113 (4%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           RHFH S   NK+  F LSDIGEGI EV +  W   VGD V++ + +C VQSDKAAV ITS
Sbjct: 20  RHFHRSVHRNKLTTFHLSDIGEGISEVELVRWNKNVGDEVEEMETVCTVQSDKAAVDITS 79

Query: 533 RYDGIITRLYHDIDQTALVGQPLVDIDVQ-DSENDGKPTDVA----PDKPVAE 676
           RY G++ +LY +  +   +G PL+DID + D+    +PT+      P KPVA+
Sbjct: 80  RYTGLVKKLYVEQGKLIKIGSPLMDIDAEDDTPAVSEPTETTKSSIPSKPVAQ 132


>UniRef50_UPI0001555D03 Cluster: PREDICTED: similar to
           2-oxoglutarate dehydrogenase complex subunit, putative,
           partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           similar to 2-oxoglutarate dehydrogenase complex subunit,
           putative, partial - Ornithorhynchus anatinus
          Length = 163

 Score =  106 bits (255), Expect = 4e-22
 Identities = 50/96 (52%), Positives = 66/96 (68%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R FH S     I  FKL DIGEGI EV + +W  ++GDNV++ D +C VQSDKAAV I+S
Sbjct: 21  RSFHHSAPRQAITTFKLCDIGEGISEVELIKWEKRIGDNVEEMDAVCTVQSDKAAVEISS 80

Query: 533 RYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGK 640
           RY GI+ +L+ D+     VG PL+DI+V+D E+D K
Sbjct: 81  RYTGIVKKLHVDVGGFIKVGAPLMDIEVEDDEDDAK 116


>UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 523

 Score =  106 bits (255), Expect = 4e-22
 Identities = 59/137 (43%), Positives = 85/137 (62%), Gaps = 4/137 (2%)
 Frame = +2

Query: 278 TTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVK 457
           TT SAR+  Q + +    +   +  R FH++  +  +    L+DIGEGI E  I +WFV+
Sbjct: 29  TTVSARSRQQPTQQRQ-QQRHCRTTRGFHSTRRLLDVKPVLLADIGEGIVECEIIQWFVE 87

Query: 458 VGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQ-DSEND 634
            G  V++F  +CEVQSDKA+V ITSR+ G++ +LY+D  + A VG+P VDID+  D E +
Sbjct: 88  PGARVEEFSPLCEVQSDKASVEITSRFSGVVKKLYYDAGEMAKVGKPFVDIDITGDLEAE 147

Query: 635 GKPT---DVAPDKPVAE 676
            +     DVAP KPV E
Sbjct: 148 PEKVLAGDVAPAKPVEE 164


>UniRef50_Q7SH25 Cluster: Putative uncharacterized protein
           NCU02704.1; n=2; Sordariales|Rep: Putative
           uncharacterized protein NCU02704.1 - Neurospora crassa
          Length = 562

 Score =  101 bits (242), Expect = 2e-20
 Identities = 56/156 (35%), Positives = 85/156 (54%), Gaps = 1/156 (0%)
 Frame = +2

Query: 209 MSILVRRSVFQLR-TVNRCRKIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNK 385
           +S L RR + ++  T    R    T+   R     S  + L + L    R FH +  +  
Sbjct: 18  VSRLSRRGLSRVAPTATSTRTPSTTSSPTRPLPGNSRSSTLAQQLPSTRRAFHATRDLKV 77

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I    L+DIGEGI E  + +WFV+ G  V++F  +CEVQSDKA+V ITSR+ G++ +LY+
Sbjct: 78  IKPVLLADIGEGIVECEVIQWFVEPGARVEEFSQLCEVQSDKASVEITSRFAGVVKKLYY 137

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
           +  + A VG+P VDID++      +     P  PV+
Sbjct: 138 EAGEMAKVGKPFVDIDIEAGPESKEVEAWTPPGPVS 173


>UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex
           subunit, putative; n=2; Theileria|Rep: 2-oxoglutarate
           dehydrogenase complex subunit, putative - Theileria
           annulata
          Length = 422

 Score =  100 bits (240), Expect = 3e-20
 Identities = 48/99 (48%), Positives = 62/99 (62%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R  H S     +  FKLSDIGEGI EV + +W   VGD V++ +++C VQSDKAAV ITS
Sbjct: 30  RFLHLSSKNLALTTFKLSDIGEGINEVQLVKWEKSVGDEVEEMESVCTVQSDKAAVEITS 89

Query: 533 RYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTD 649
           RY GI+ +LY +   T  +G PL+DID  D   D  P +
Sbjct: 90  RYTGIVKKLYVNEGDTVKIGSPLMDIDTVDEVPDDTPNN 128


>UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain
           transacylase, putative; n=3; Trypanosoma|Rep:
           Dihydrolipoamide branched chain transacylase, putative -
           Trypanosoma brucei
          Length = 439

 Score =  100 bits (239), Expect = 4e-20
 Identities = 45/94 (47%), Positives = 66/94 (70%)
 Frame = +2

Query: 365 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 544
           T     + + +KL+DIGEGI+EV +   +VK GD + +F+ ICEVQSDKA V ITSRY G
Sbjct: 20  TRSRCGRTIPYKLADIGEGIKEVEVVTLYVKPGDRIGEFEKICEVQSDKATVEITSRYAG 79

Query: 545 IITRLYHDIDQTALVGQPLVDIDVQDSENDGKPT 646
           +IT ++ +  + A VG+P+VDI+V D++   KP+
Sbjct: 80  VITTVHIEAGEKAHVGEPIVDIEVNDTDETQKPS 113


>UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1;
           Dictyostelium discoideum AX4|Rep: Dihydrolipoyl
           transacylase - Dictyostelium discoideum AX4
          Length = 517

 Score =  100 bits (239), Expect = 4e-20
 Identities = 43/79 (54%), Positives = 58/79 (73%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           + F L+D+GEGI E  +  W+VK GD +++FD +CEVQSDKA V ITSRYDGI+T++ H 
Sbjct: 78  IKFNLADVGEGIAECEVLVWYVKEGDQIKEFDKLCEVQSDKATVEITSRYDGIVTKICHK 137

Query: 569 IDQTALVGQPLVDIDVQDS 625
           I   A VG+PLV+I  + S
Sbjct: 138 IGDMAKVGEPLVEITPESS 156


>UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 480

 Score = 96.3 bits (229), Expect = 6e-19
 Identities = 45/96 (46%), Positives = 68/96 (70%), Gaps = 1/96 (1%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           ++FH S   + I  F L+DIGEGI+E  I +WFV+    V+++D +CEVQSDKA+V ITS
Sbjct: 31  KYFHASAKRSAIKPFMLADIGEGIKECEIIQWFVEPEARVEEWDKLCEVQSDKASVEITS 90

Query: 533 RYDGIITRLYHDIDQTALVGQPLVDIDVQ-DSENDG 637
           R+ G+I +L+++    A VG+ L+DID+Q + E +G
Sbjct: 91  RFSGVIKKLHYEAGDMAQVGKALLDIDIQGEIEQEG 126


>UniRef50_Q4P9L5 Cluster: Putative uncharacterized protein; n=1;
            Ustilago maydis|Rep: Putative uncharacterized protein -
            Ustilago maydis (Smut fungus)
          Length = 1496

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 51/103 (49%), Positives = 66/103 (64%), Gaps = 3/103 (2%)
 Frame = +2

Query: 335  SLSKELRHFHTS--HAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSD 508
            S S  LR F T+      ++  + L+D+GEGI E  I +WFV+ G  VQ+FD ICEVQSD
Sbjct: 1024 SSSTSLRSFATTPRRLAVEVKPYLLADVGEGITECEIIKWFVQPGAVVQEFDPICEVQSD 1083

Query: 509  KAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQ-DSEND 634
            KA+V ITSRY G I RL H     A VG PL +I+++ D EN+
Sbjct: 1084 KASVEITSRYAGKIKRLMHKEGDVAKVGHPLCEIEMESDGENE 1126


>UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9;
           Eurotiomycetidae|Rep: Dihydrolipoamide transacylase -
           Aspergillus oryzae
          Length = 476

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 43/110 (39%), Positives = 69/110 (62%), Gaps = 2/110 (1%)
 Frame = +2

Query: 335 SLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKA 514
           ++S   R FH + A+  + +  L D+GEGI EV I +W+V+ G +++++  +C+ QSDKA
Sbjct: 31  TISFPRRTFHAAPALWGVKSQILKDVGEGITEVQIIQWYVEEGAHIEEWKPLCQYQSDKA 90

Query: 515 AVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSE--NDGKPTDVAP 658
              ITSRY+GI+ +L+   D T   G+ L DI+V+D +   D  P + AP
Sbjct: 91  VDDITSRYEGIVKKLHFQADDTVPTGRALCDIEVEDGKYPEDNPPPEPAP 140


>UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain
           transacylase, putative; n=2; Leishmania|Rep:
           Dihydrolipoamide branched chain transacylase, putative -
           Leishmania major
          Length = 477

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 47/107 (43%), Positives = 64/107 (59%), Gaps = 5/107 (4%)
 Frame = +2

Query: 353 RH-FHTSHA-VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTI 526
           RH F T+ A + + + ++L+DIGEGI EV +    VK GD + +FD ICEVQSDKA V I
Sbjct: 34  RHLFATTCAPLGRCIPYRLADIGEGITEVQVLGVCVKAGDTINEFDPICEVQSDKATVDI 93

Query: 527 TSRYDGIITRLYHDIDQTALVGQPLVDI---DVQDSENDGKPTDVAP 658
           TSRY G++  +Y     TA VG  ++DI      D+     P+  AP
Sbjct: 94  TSRYTGVVKAVYLQPGATAKVGSVMLDIVPEGADDAPEAASPSRSAP 140


>UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8;
           Plasmodium|Rep: Plasmodium vivax PV1H14105_P -
           Plasmodium yoelii yoelii
          Length = 465

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 43/98 (43%), Positives = 61/98 (62%), Gaps = 2/98 (2%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R  +TS+   KIV  KL DIGEGI EV I +W  ++GD V + +++  VQSDKAAV ITS
Sbjct: 25  RFINTSNVNLKIVKCKLFDIGEGISEVEITQWNKQIGDEVSEMESLLTVQSDKAAVDITS 84

Query: 533 RYDGIITRLYHDIDQTALVGQPLVDIDVQD--SENDGK 640
           +Y+GI+ + Y +      +G    +ID QD   E +G+
Sbjct: 85  KYNGILVKKYANDKDIIKIGSYFCEIDTQDEVGEEEGE 122


>UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_34,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 419

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 37/96 (38%), Positives = 59/96 (61%), Gaps = 1/96 (1%)
 Frame = +2

Query: 359 FHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRY 538
           F + +    +  FKL D+GE I+E  IK+W VK+GD+V +FD + +V +DK    I S Y
Sbjct: 7   FLSRYYFGAVKIFKLPDLGEKIKEATIKKWHVKIGDHVNEFDPVADVSTDKMFTQIPSNY 66

Query: 539 DGIITRLYHDIDQTALVGQPLVDIDVQ-DSENDGKP 643
            G I +L+H  D+T LVG   ++I+++ D++    P
Sbjct: 67  TGKIHKLFHQEDETCLVGGDFLEIEIESDNQESATP 102


>UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid
           dehydrogenase E2 subunit; n=9; Magnoliophyta|Rep:
           Branched chain alpha-keto acid dehydrogenase E2 subunit
           - Arabidopsis thaliana (Mouse-ear cress)
          Length = 483

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 37/88 (42%), Positives = 55/88 (62%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           ++   L+  GEGI E  + +WFVK GD+V++F  +CEVQSDKA + ITSR+ G +  + H
Sbjct: 75  LIDVPLAQTGEGIAECELLKWFVKEGDSVEEFQPLCEVQSDKATIEITSRFKGKVALISH 134

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTD 649
                  VG+ LV + V+DS++    TD
Sbjct: 135 SPGDIIKVGETLVRLAVEDSQDSLLTTD 162


>UniRef50_Q5KP05 Cluster: Tricarboxylic acid cycle-related protein,
           putative; n=2; Filobasidiella neoformans|Rep:
           Tricarboxylic acid cycle-related protein, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 633

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 42/100 (42%), Positives = 54/100 (54%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R  H S A  K+  FKL DIGEGI EV I +W V  G  V++FD +CEVQSDK+ V +TS
Sbjct: 45  RPLHQSSAALKLSPFKLHDIGEGITEVEILKWHVTDGQAVEEFDALCEVQSDKSVVELTS 104

Query: 533 RYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDV 652
              GI+  +  D      VG  L  I+  +   D    D+
Sbjct: 105 HAKGIVRDIKTDPGHMVKVGTVLCVIETDEPSEDAAEDDL 144


>UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex, E2
           component, dihydrolipoamide succinyltransferase; n=2;
           Lactobacillales|Rep: Acetoin/pyruvate dehydrogenase
           complex, E2 component, dihydrolipoamide
           succinyltransferase - Leuconostoc mesenteroides subsp.
           mesenteroides (strain ATCC 8293 /NCDO 523)
          Length = 431

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 40/88 (45%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FK+ DIGEG+ E  I  W VKVGD +   D + EVQ+DK    I S Y G +T+L+ D  
Sbjct: 5   FKMPDIGEGMAEGDITSWLVKVGDTIAADDPVAEVQNDKLMQEILSPYGGKVTKLFVDAG 64

Query: 575 QTALVGQPLVDIDVQ-DSENDGKPTDVA 655
            T  VG PL++ D    SEND     VA
Sbjct: 65  TTVEVGDPLIEFDGDGSSENDSDNGHVA 92


>UniRef50_A6TMP1 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=1; Alkaliphilus
           metalliredigens QYMF|Rep: Catalytic domain of components
           of various dehydrogenase complexes - Alkaliphilus
           metalliredigens QYMF
          Length = 438

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 33/86 (38%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           +V FK  DIGEGI E ++ +W VK GDN+++ +++CEV++DK    + S   G++  L  
Sbjct: 1   MVEFKFPDIGEGISEGILTKWMVKAGDNIKEGESLCEVETDKVTTELPSPATGLVNSLKG 60

Query: 566 DIDQTALVGQPLVDIDVQD-SENDGK 640
           +   T  VG  +V ID  D +E + K
Sbjct: 61  EEGDTIYVGDVIVKIDTGDHAEEESK 86


>UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase,
           putative; n=1; Babesia bovis|Rep: Dihydrolipoamide
           succinyltransferase, putative - Babesia bovis
          Length = 402

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 36/112 (32%), Positives = 58/112 (51%), Gaps = 4/112 (3%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R  H S  + ++   KL  +G+ I E  + EW   VG++V+  + I  V++DK  V I S
Sbjct: 44  RSLHVSSTLLEVKTMKLPSLGDSISEGTLSEWKKNVGESVEVDEPIAIVETDKVTVDINS 103

Query: 533 RYDGIITRLYHDIDQTALVGQPLVDIDVQDS----ENDGKPTDVAPDKPVAE 676
              G+I + ++++D T LVG+P +D+D   S           D    +PVAE
Sbjct: 104 TLSGVIVKQHYEVDDTVLVGKPFIDVDAGGSAAAPAETASGVDSKSPEPVAE 155


>UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransferase;
           n=1; Tetrahymena thermophila SB210|Rep: 2-oxo acid
           dehydrogenases acyltransferase - Tetrahymena thermophila
           SB210
          Length = 462

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 35/85 (41%), Positives = 53/85 (62%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I  FKL D+GE I+E  +K+ +VK GD V++F  I +V +DK    I S Y G I +++H
Sbjct: 27  IKPFKLPDLGEKIKEATVKKLYVKEGDIVEEFQTIADVATDKLFTQIPSSYAGKIHKVFH 86

Query: 566 DIDQTALVGQPLVDIDVQDSENDGK 640
             + T LVG   V+I+V D ++ G+
Sbjct: 87  KEEDTCLVGDVFVEIEV-DEDHSGE 110


>UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E2
           component; n=2; Alteromonadales|Rep: Apha keto acid
           dehydrogenase complex, E2 component - Idiomarina baltica
           OS145
          Length = 515

 Score = 69.3 bits (162), Expect = 8e-11
 Identities = 38/91 (41%), Positives = 53/91 (58%), Gaps = 3/91 (3%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L DIGEGI E  I EW V  GD V++   + EV +DKA V I ++ DG++ +LY+   
Sbjct: 5   FILPDIGEGIVECEIVEWLVAEGDTVKEDQPVVEVMTDKAMVEIPAKDDGVVEKLYYQKG 64

Query: 575 QTALVGQPLVDIDVQ-DSENDGKPT--DVAP 658
             A V +PL  I+ + D+ +D  P   D AP
Sbjct: 65  DIAKVHEPLFRINAEGDASDDAAPASDDAAP 95



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 34/84 (40%), Positives = 44/84 (52%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L DIGEGI E  I EW V  GD V++   + EV +DKA V I ++ DG + +LYH   
Sbjct: 106 FILPDIGEGIVECEIVEWLVSEGDEVKEDQPVVEVMTDKATVEIPAKEDGKVVKLYHKKG 165

Query: 575 QTALVGQPLVDIDVQDSENDGKPT 646
             A V +PL  +         K T
Sbjct: 166 DIAEVHKPLFALQPAGGVEPSKQT 189


>UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2
           component; n=1; Aeropyrum pernix|Rep: Pyruvate
           dehydrogenase complex, E2 component - Aeropyrum pernix
          Length = 412

 Score = 69.3 bits (162), Expect = 8e-11
 Identities = 40/99 (40%), Positives = 54/99 (54%)
 Frame = +2

Query: 377 VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR 556
           + +IV  KL DIGEGI E  I EW V+ G  V+QF  +  V + KA V I S Y G + R
Sbjct: 1   MGRIVQVKLPDIGEGIAEGEIVEWLVEEGAVVKQFSPLVRVLTAKATVEIPSPYTGRVVR 60

Query: 557 LYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
           L         VG P+++I+V++ E    P   A +KP A
Sbjct: 61  LLAKPGDVVRVGDPIIEIEVEEGEAPKAPE--AAEKPSA 97


>UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase
           component of 2-oxoglutarate dehydrogenase complex,
           mitochondrial, putative; n=2; Theileria|Rep:
           Dihydrolipoamide succinyltransferase component of
           2-oxoglutarate dehydrogenase complex, mitochondrial,
           putative - Theileria annulata
          Length = 457

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 33/93 (35%), Positives = 55/93 (59%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I    +  +G+ I E  + +W V VGD +   D I  V++DK +V + S + G++T+ + 
Sbjct: 72  IKVINVPTLGDSISEGTLTKWAVSVGDYLNVDDLIAVVETDKVSVDVNSPFSGVLTKTFS 131

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDK 664
           +   T LVG+PLV+ID+      GKP++ AP+K
Sbjct: 132 NTGDTILVGKPLVEIDLA-----GKPSEKAPEK 159


>UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
           halodurans|Rep: Pyruvate dehydrogenase E2 - Bacillus
           halodurans
          Length = 414

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 32/76 (42%), Positives = 48/76 (63%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           +V F+L D+GEG+ E  I  WFV+ GD+V+Q + + EVQ+DK    +T+   G I R+Y+
Sbjct: 1   MVEFRLPDVGEGMHEGEIISWFVQEGDHVKQDEPVVEVQTDKMNAELTAPVSGKIKRVYY 60

Query: 566 DIDQTALVGQPLVDID 613
            + + A VG  L  ID
Sbjct: 61  KVGEVAEVGSLLFTID 76


>UniRef50_UPI00006D8691 Cluster: COG0508: Pyruvate/2-oxoglutarate
           dehydrogenase complex, dihydrolipoamide acyltransferase
           (E2) component, and related enzymes; n=1; Pseudomonas
           aeruginosa C3719|Rep: COG0508: Pyruvate/2-oxoglutarate
           dehydrogenase complex, dihydrolipoamide acyltransferase
           (E2) component, and related enzymes - Pseudomonas
           aeruginosa C3719
          Length = 129

 Score = 66.5 bits (155), Expect = 6e-10
 Identities = 30/78 (38%), Positives = 49/78 (62%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL D+GEG++E  I EW VK GD+V+    +  V++ KA V I + YDG++ +L+    
Sbjct: 4   FKLPDLGEGLQEAEIVEWHVKAGDSVRADQRLVSVETAKALVDIPAPYDGVVGKLFGAEG 63

Query: 575 QTALVGQPLVDIDVQDSE 628
               VG+PLV  + ++++
Sbjct: 64  DILHVGEPLVGFEGEEAD 81


>UniRef50_Q15U82 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=3; Gammaproteobacteria|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Pseudoalteromonas atlantica (strain T6c /
           BAA-1087)
          Length = 555

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 31/79 (39%), Positives = 47/79 (59%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L DIGEGI E  + EW V  GD++ +   + EV +DKA V I + Y G + +LY+   
Sbjct: 4   FILPDIGEGIVECELLEWLVCEGDSIVEDQPVAEVMTDKATVQIPAMYSGTVKKLYYQAG 63

Query: 575 QTALVGQPLVDIDVQDSEN 631
           + A V +PL  +D++  E+
Sbjct: 64  EIAQVHKPLFAMDIEGHES 82



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 28/83 (33%), Positives = 42/83 (50%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L DIGEGI E  + +W V  G++V +   + EV +DKA V I +++ G I  L +   
Sbjct: 136 FILPDIGEGIVECELVKWLVSEGEDVIEDQPVVEVMTDKALVEIPAKHSGTIVSLCYQRG 195

Query: 575 QTALVGQPLVDIDVQDSENDGKP 643
             A V   L  + V   ++   P
Sbjct: 196 DIANVHSALFTMRVAGVDDKALP 218


>UniRef50_P09062 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-keto acid dehydrogenase complex (EC
           2.3.1.168) (Dihydrolipoyllysine-residue (2-
           methylpropanoyl)transferase); n=27; Proteobacteria|Rep:
           Lipoamide acyltransferase component of branched-chain
           alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
           (Dihydrolipoyllysine-residue (2-
           methylpropanoyl)transferase) - Pseudomonas putida
          Length = 423

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 39/97 (40%), Positives = 53/97 (54%), Gaps = 5/97 (5%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+ DIGEGI +V + EWFVKVGD + +   + +V +DKA V I S   G +  L     +
Sbjct: 7   KMPDIGEGIAQVELVEWFVKVGDIIAEDQVVADVMTDKATVEIPSPVSGKVLALGGQPGE 66

Query: 578 TALVGQPLVDIDVQDSEN-----DGKPTDVAPDKPVA 673
              VG  L+ I+V+ S N       KP +V P  PVA
Sbjct: 67  VMAVGSELIRIEVEGSGNHVDVPQAKPAEV-PAAPVA 102


>UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex; n=80; Bacilli|Rep: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex - Bacillus subtilis
          Length = 442

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 35/79 (44%), Positives = 44/79 (55%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL DIGEGI E  I +WFVK  D V + D + EVQ+DKA V I S   G +  L  +  
Sbjct: 5   FKLPDIGEGIHEGEIVKWFVKPNDEVDEDDVLAEVQNDKAVVEIPSPVKGKVLELKVEEG 64

Query: 575 QTALVGQPLVDIDVQDSEN 631
             A VGQ ++  D    E+
Sbjct: 65  TVATVGQTIITFDAPGYED 83


>UniRef50_A0JUQ7 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=9; Actinobacteria
           (class)|Rep: Catalytic domain of components of various
           dehydrogenase complexes - Arthrobacter sp. (strain FB24)
          Length = 462

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 35/91 (38%), Positives = 51/91 (56%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I  F+L D+GEG+ E  I  W V VGD V     I EV++ KA V + S + G+IT L+ 
Sbjct: 2   IKEFRLPDLGEGLTESEILSWKVAVGDTVALNQVIAEVETAKAVVELPSPFAGVITALHE 61

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTDVAP 658
                  VG+P+V  +V+   +DG P+  +P
Sbjct: 62  QPGTVVEVGKPIVSFEVEG--DDGGPSAASP 90


>UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-keto acid dehydrogenase complex (EC
           2.3.1.168) (Dihydrolipoyllysine-residue (2-
           methylpropanoyl)transferase); n=22; Proteobacteria|Rep:
           Lipoamide acyltransferase component of branched-chain
           alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
           (Dihydrolipoyllysine-residue (2-
           methylpropanoyl)transferase) - Pseudomonas aeruginosa
          Length = 428

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+ DIGEGI EV + EW V+VGD+V +   + EV +DKA V I S   G I  L     Q
Sbjct: 7   KMPDIGEGIAEVELVEWHVQVGDSVNEDQVLAEVMTDKATVEIPSPVAGRILALGGQPGQ 66

Query: 578 TALVGQPLVDIDVQDSENDGK-PTDVAPDKPVA 673
              VG  L+ ++V+ + N  + P    P  PVA
Sbjct: 67  VMAVGGELIRLEVEGAGNLAESPAAATPAAPVA 99


>UniRef50_A4BTC4 Cluster: Dihydrolipoamide acetyltransferase; n=20;
           Proteobacteria|Rep: Dihydrolipoamide acetyltransferase -
           Nitrococcus mobilis Nb-231
          Length = 382

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 34/90 (37%), Positives = 47/90 (52%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL D+GEG+ E  I EWFV+VG+ +++   +  V++DKA V I S   G I  L  D  
Sbjct: 4   FKLPDLGEGLVEAEIVEWFVRVGEQIERDQPLVSVETDKAIVEIPSPQTGRIEELLGDAG 63

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDVAPDK 664
               VG PLV     ++    + T  A  K
Sbjct: 64  DVMHVGDPLVVFGGDEARGQEQRTSAATPK 93


>UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 component,
            dihydrolipoamide succinyltransferase, putative; n=12;
            cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E2
            component, dihydrolipoamide succinyltransferase, putative
            - Plasmodium yoelii yoelii
          Length = 1632

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 42/147 (28%), Positives = 72/147 (48%), Gaps = 2/147 (1%)
 Frame = +2

Query: 206  AMSILVRRSVFQLRTVNRCRKIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNK 385
            A S+  +RS+F+  ++ R +      Q   NG+ +  +   N    + + ++ T      
Sbjct: 1197 ATSLFRKRSIFE--SIFRKKSKNCIKQLIYNGNNVK-RAFFNVEFRQLVNNYITCKRHFS 1253

Query: 386  IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
            I   K+  +G+ I E VI EW  KVGD V   + +  + +DK +V I S+  G + +++ 
Sbjct: 1254 IDTLKVPRLGDSITEGVINEWKKKVGDYVYSDETLAVIDTDKVSVDINSKSSGALHKIFA 1313

Query: 566  DIDQTALVGQPLVDID--VQDSENDGK 640
            +     LV  PL +ID   Q +END K
Sbjct: 1314 EAGDVVLVDSPLCEIDTSAQPNENDIK 1340


>UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;
           n=2; Anaeromyxobacter|Rep: Dehydrogenase complex
           catalytic domain - Anaeromyxobacter sp. Fw109-5
          Length = 454

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 28/74 (37%), Positives = 47/74 (63%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           +L DIGEG+ E  +++WFVK GD+V +   + EV +DKA V I S   G + +L+  +  
Sbjct: 6   ELPDIGEGVVEAEVQQWFVKPGDDVAEDQPLVEVMTDKATVVIPSPKRGRVVKLFFGVGD 65

Query: 578 TALVGQPLVDIDVQ 619
            A V  PL++++++
Sbjct: 66  LAKVHSPLLELELE 79


>UniRef50_A0K281 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=2; Arthrobacter|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Arthrobacter sp. (strain FB24)
          Length = 527

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 36/93 (38%), Positives = 51/93 (54%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ E  I  W VK GD+V   D +CE+++ K+ V + S + G +T L   + 
Sbjct: 6   FNLPDVGEGLTEAEIVSWNVKPGDSVAINDILCEIETAKSLVELPSPFAGTVTELLVPVG 65

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
            T  VG P+  I V D+ + G PT      PVA
Sbjct: 66  VTVDVGTPI--ISVSDAVS-GDPTPADAPVPVA 95


>UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2;
           Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
           kaustophilus
          Length = 431

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 1/96 (1%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I  FKL DIGEG+ E  I  W V+ GD V+    I E+Q+DKA V +T+   G +  L  
Sbjct: 2   IYEFKLPDIGEGLHEAEIIRWLVREGDVVKADQPIAEIQTDKAMVEMTTPVAGKVVALAG 61

Query: 566 DIDQTALVGQPLVDIDVQDS-ENDGKPTDVAPDKPV 670
               T  VG+PL+ ++ + S   +  P + +  +PV
Sbjct: 62  PEGATVKVGEPLIVVETEASVAGEATPIEDSVREPV 97


>UniRef50_Q1GTH9 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=5; Alphaproteobacteria|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Sphingopyxis alaskensis (Sphingomonas
           alaskensis)
          Length = 441

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 32/95 (33%), Positives = 50/95 (52%)
 Frame = +2

Query: 392 AFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDI 571
           +F+L DIGEGI E  I  W VKVG+ V++   + ++ +DKA V + S   G++  L  ++
Sbjct: 5   SFRLPDIGEGIAEAEIVAWHVKVGERVEEDAQLADMMTDKATVEMESPVSGVVVELAGEV 64

Query: 572 DQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
                +G  L  I+  D + DG       D PV +
Sbjct: 65  GDLIPIGSTLAVIET-DDDGDGALDAPPADTPVED 98


>UniRef50_A0LQU7 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=1; Acidothermus
           cellulolyticus 11B|Rep: Catalytic domain of components
           of various dehydrogenase complexes - Acidothermus
           cellulolyticus (strain ATCC 43068 / 11B)
          Length = 546

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 30/83 (36%), Positives = 46/83 (55%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F+L D+GEG+ E  I  W V+ GD V Q   I E+++ KA V + S + GI+  +     
Sbjct: 7   FRLPDVGEGLTEAEITRWHVRPGDRVGQNQVIAEIETAKALVELPSPFAGIVAEILVAEG 66

Query: 575 QTALVGQPLVDIDVQDSENDGKP 643
            T  VG P++ IDV  +++   P
Sbjct: 67  TTVPVGTPIIGIDVAAAQSGAHP 89


>UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8;
           Mycoplasma|Rep: DIHYDROLIPOAMIDE DEHYDROGENASE -
           Mycoplasma pulmonis
          Length = 627

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FK +DIGEG+ E  + E +VK+GD V++ D++  V++DK    I S   G+I ++  ++ 
Sbjct: 4   FKFADIGEGLHEGKVAEIYVKLGDTVKEGDSLFSVETDKITSDIPSPTGGVINKILFELG 63

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDVAPD-KPVAE 676
            T  VG+ +  ID         P   A + KP AE
Sbjct: 64  GTVHVGEEIFWIDDGSGPASDSPEPAAAEAKPAAE 98


>UniRef50_A1RJV4 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=25; Gammaproteobacteria|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Shewanella sp. (strain W3-18-1)
          Length = 536

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 30/75 (40%), Positives = 44/75 (58%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L DIGEG+ E  + EW VK GD V +   I +V +DKA V I + + G++T+LY+   
Sbjct: 5   FILPDIGEGVVECELVEWLVKEGDTVVEDQPIADVMTDKALVQIPAPFAGVVTKLYYAKG 64

Query: 575 QTALVGQPLVDIDVQ 619
             A V  PL  + ++
Sbjct: 65  DIAKVHAPLYAVQIE 79



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 33/80 (41%), Positives = 45/80 (56%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I  F L DIGEGI E  + EW V  GD V++   I +V +DKA V I +   G I +L++
Sbjct: 120 IEEFLLPDIGEGIVECELVEWLVSEGDWVEEDQPIADVMTDKALVQIPAIKAGKIAKLHY 179

Query: 566 DIDQTALVGQPLVDIDVQDS 625
              Q A V  PL  I+V+ +
Sbjct: 180 RKGQLAKVHTPLFAIEVEQT 199


>UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2;
           Actinomycetales|Rep: Pyruvate dehydrogenase E2 -
           Arthrobacter aurescens (strain TC1)
          Length = 493

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 29/72 (40%), Positives = 42/72 (58%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL D+GEG+ E  +  W V VGD +     I EV++ K+ V + S Y G +  L+ +  
Sbjct: 8   FKLPDLGEGLTEAELVNWLVAVGDEIVVDQPIAEVETAKSMVEVPSPYAGTVAELHGEAG 67

Query: 575 QTALVGQPLVDI 610
           QT  VG+PL+ I
Sbjct: 68  QTLDVGKPLISI 79


>UniRef50_A6PJ30 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=1; Shewanella sediminis
           HAW-EB3|Rep: Catalytic domain of components of various
           dehydrogenase complexes - Shewanella sediminis HAW-EB3
          Length = 544

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 34/98 (34%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I  F L DIGEG+ E  + EW V  GD V +   I +V +DKA V I + + G+I +L++
Sbjct: 2   IKEFILPDIGEGVVECELVEWLVSEGDTVSEDQPIADVMTDKALVQIPAPHAGVIKKLHY 61

Query: 566 DIDQTALVGQPLVDIDVQDSENDG-KPTDVAPDKPVAE 676
              + A V  PL  +D++ + +     + V  D+  AE
Sbjct: 62  AKGEIAKVHAPLYSVDIKGNSSPAIDASSVVDDQMDAE 99



 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 30/79 (37%), Positives = 45/79 (56%)
 Frame = +2

Query: 383 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 562
           ++  F L DIGEGI E  + EW V  G+ V +   I +V +DKA V I +   G I +L+
Sbjct: 121 QVEEFLLPDIGEGIVECELVEWLVSEGEQVVEDQPIADVMTDKALVQIPAIKSGKIVKLH 180

Query: 563 HDIDQTALVGQPLVDIDVQ 619
           +   Q A V +PL  ++V+
Sbjct: 181 YRKGQLAKVHEPLFAVEVE 199


>UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2;
           Alphaproteobacteria|Rep: Dihydrolipoamide
           acetyltransferase - Oceanicaulis alexandrii HTCC2633
          Length = 437

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 34/94 (36%), Positives = 51/94 (54%), Gaps = 6/94 (6%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           +KL D+GEG+ E  I EW +K GD V +  +I +V +DKA V I    +G++  +  +  
Sbjct: 6   YKLPDVGEGVVEAEIVEWHIKAGDKVTEDQHILDVMTDKATVEIPCAVNGVVKSIVGEPG 65

Query: 575 QTALVGQPLVDIDV-----QDSENDGKP-TDVAP 658
           +   VG  ++ IDV      D EN  +P T  AP
Sbjct: 66  EVIAVGTEILVIDVDGEVPDDVENTAEPETKDAP 99


>UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-keto acid dehydrogenase complex;
           n=14; Burkholderia|Rep: Lipoamide acyltransferase
           component of branched-chain alpha-keto acid
           dehydrogenase complex - Burkholderia pseudomallei
           (Pseudomonas pseudomallei)
          Length = 483

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 32/78 (41%), Positives = 44/78 (56%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+ DIGEGI EV +  W VKVGD V++   I +V +DKA+V I S   G++  L      
Sbjct: 7   KMPDIGEGIAEVELGLWHVKVGDRVKEDQAIADVMTDKASVEIPSPVTGVVVALGGKEGD 66

Query: 578 TALVGQPLVDIDVQDSEN 631
              VG  LV ++V+   N
Sbjct: 67  VLAVGSELVRLEVEGDGN 84


>UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase
           component of pyruvate dehydrogenase complex E2; n=3;
           Halobacteriaceae|Rep: Dihydrolipoamide
           S-acetyltransferase component of pyruvate dehydrogenase
           complex E2 - Haloarcula marismortui (Halobacterium
           marismortui)
          Length = 540

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 32/93 (34%), Positives = 50/93 (53%)
 Frame = +2

Query: 380 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           N +  F+L D+GEG+ E  +  W V+ GD V +   + EV++DKA V + S  DG++  L
Sbjct: 31  NMVREFELPDVGEGVAEGELLRWRVEPGDAVSEDQPVAEVETDKAVVDVPSPVDGVVEEL 90

Query: 560 YHDIDQTALVGQPLVDIDVQDSENDGKPTDVAP 658
                +   VG  ++   V D E+  K T+ AP
Sbjct: 91  RAAEGEMVPVGDVIIVFRV-DGEDGPKATETAP 122


>UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of
           pyruvate dehydrogenase E2 component; n=1; Mycoplasma
           penetrans|Rep: Dihydrolipoamide acetyltransferase of
           pyruvate dehydrogenase E2 component - Mycoplasma
           penetrans
          Length = 478

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 28/89 (31%), Positives = 50/89 (56%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FK +DIGEGI E  + +  VK GD+V+   ++  V++DK    ++S  +G+I+++   + 
Sbjct: 4   FKFADIGEGIHEGKVSDILVKEGDSVKDGTDLFSVETDKITTEVSSPVNGVISKILIKVG 63

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDVAPD 661
            T  VG P+ +ID  +  +       AP+
Sbjct: 64  DTIHVGDPIFEIDDSNGSSSSAAPAQAPE 92


>UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid
           dehydrogenase component; n=1; Nocardia farcinica|Rep:
           Putative branched-chain alpha-keto acid dehydrogenase
           component - Nocardia farcinica
          Length = 510

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 28/80 (35%), Positives = 43/80 (53%)
 Frame = +2

Query: 371 HAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGII 550
           H    ++ F+L D+GEG+ +  +  W V VGD+V     I EV++ KA V +   Y G +
Sbjct: 2   HDDGNVLEFRLPDLGEGLTDAELVSWSVAVGDHVDLNQTIAEVETAKAVVALPCPYAGTV 61

Query: 551 TRLYHDIDQTALVGQPLVDI 610
             L  D  +T  VG PL+ +
Sbjct: 62  AALLADPGETVPVGAPLIRV 81


>UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2
           component, dihydrolipoamide acetyltransferase; n=4;
           Geobacter|Rep: Pyruvate dehydrogenase complex E2
           component, dihydrolipoamide acetyltransferase -
           Geobacter sulfurreducens
          Length = 392

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 31/78 (39%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS-RYDGIITRLYHDI 571
           FKL D+GEGI E  ++ W VK GD V +   + EV++DKA V + S R   +ITR   + 
Sbjct: 5   FKLPDLGEGITEAELRRWLVKEGDTVAEHQPVVEVETDKAVVEVPSPRAGRVITRARLE- 63

Query: 572 DQTALVGQPLVDIDVQDS 625
            +T +VG+ L+ I  +++
Sbjct: 64  GETVMVGETLLTIAEEEA 81


>UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 /
           dihydrolipoamide acetyltransferase; n=3;
           Thermoplasma|Rep: Pyruvate dehydrogenase E2 /
           dihydrolipoamide acetyltransferase - Thermoplasma
           volcanium
          Length = 400

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 31/73 (42%), Positives = 43/73 (58%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL DIGEG+ E  I +W V  GD V++  ++ EV +DK  V I S  +G I+++ +   
Sbjct: 4   FKLPDIGEGVTEGEIVKWDVAEGDEVKKDQDLVEVMTDKVTVKIPSPVNGKISKILYKEG 63

Query: 575 QTALVGQPLVDID 613
           Q   VG  LV ID
Sbjct: 64  QVVPVGSTLVQID 76


>UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase
           component of pyruvate dehydrogenase complex; n=2;
           Halobacteriaceae|Rep: Dihydrolipoamide acetyltransferase
           component of pyruvate dehydrogenase complex - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 545

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 30/87 (34%), Positives = 47/87 (54%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ E  +  W V  GD V +   + EV++DKAAV + S  DG++  L+ ++ 
Sbjct: 4   FNLPDLGEGVAEGEVLTWRVSPGDAVTEDQVLAEVETDKAAVDVPSPVDGVVQELHAEVG 63

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDVA 655
           +    G+ L+ I     E D +  D A
Sbjct: 64  EMVQTGEVLITI---AEEGDAETADAA 87


>UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep:
           Lin1411 protein - Listeria innocua
          Length = 416

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 32/84 (38%), Positives = 45/84 (53%)
 Frame = +2

Query: 374 AVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIIT 553
           AV KI   KL   GE + E  I  W VK GD V+++D I EV +DK    I S + G I 
Sbjct: 2   AVEKITMPKL---GESVTEGTISSWLVKPGDTVEKYDAIAEVLTDKVTAEIPSSFSGTIK 58

Query: 554 RLYHDIDQTALVGQPLVDIDVQDS 625
            +  + D+T  VG+ +  I+  D+
Sbjct: 59  EILAEEDETLEVGEVICTIETADA 82


>UniRef50_A3JES0 Cluster: 2-oxoglutarate dehydrogenase E2; n=1;
           Marinobacter sp. ELB17|Rep: 2-oxoglutarate dehydrogenase
           E2 - Marinobacter sp. ELB17
          Length = 250

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 34/86 (39%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L DIGEGI E  + +W V  GD +++   + EV +DKA V I + + G I RLY+   
Sbjct: 4   FILPDIGEGIVECEVVKWLVSEGDMIEEDQPVVEVMTDKALVEIPAPHKGQIKRLYYKEG 63

Query: 575 QTALVGQPLVDIDVQDSE-NDGKPTD 649
             A V  PL ++  + SE  DG   D
Sbjct: 64  DIAKVHAPLFELLEEGSEQEDGTIND 89


>UniRef50_A0JY25 Cluster: Biotin/lipoyl attachment domain-containing
           protein; n=1; Arthrobacter sp. FB24|Rep: Biotin/lipoyl
           attachment domain-containing protein - Arthrobacter sp.
           (strain FB24)
          Length = 109

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 27/79 (34%), Positives = 46/79 (58%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           ++F L D+GEG+ E  + EW V  GD V++   + EV++ K+AV + S   G + R++  
Sbjct: 4   ISFPLPDLGEGLIEATVLEWLVSPGDQVERNQPLVEVETTKSAVELPSPQAGKVVRIHGG 63

Query: 569 IDQTALVGQPLVDIDVQDS 625
                 VG+PL+  +V D+
Sbjct: 64  PGDRINVGEPLIVFEVPDN 82


>UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3;
           Cystobacterineae|Rep: Lipoamide acyltransferase -
           Myxococcus xanthus
          Length = 416

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 29/78 (37%), Positives = 47/78 (60%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I  FKL D+GEG+ E  + +W VK GD+V++   + EV +DKA VT+ +   G + + + 
Sbjct: 3   IFEFKLPDLGEGVMEGELVKWHVKAGDSVKEDQVLAEVMTDKATVTVPAPKAGRVVKTHG 62

Query: 566 DIDQTALVGQPLVDIDVQ 619
           +    A V Q LV ++V+
Sbjct: 63  NEGDMAKVHQLLVTLEVE 80


>UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic domain
           of components of various dehydrogenase complexes:E3
           binding; n=2; Frankia|Rep: Biotin/lipoyl
           attachment:Catalytic domain of components of various
           dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
          Length = 585

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 30/84 (35%), Positives = 44/84 (52%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F+L D+GEG+ E  I  W V+VG+ V     + EV++ KA V I S + G++   + +  
Sbjct: 6   FRLPDLGEGLTEAEIVRWLVEVGETVTVNQPLVEVETAKAVVEIPSPFAGVLVERHGEAG 65

Query: 575 QTALVGQPLVDIDVQDSENDGKPT 646
               VG PL+ ID    E    PT
Sbjct: 66  TELAVGTPLLTIDEPGDEPATGPT 89


>UniRef50_Q83DQ8 Cluster: Dehydrogenase, E2 component,
           acyltransferase; n=5; Gammaproteobacteria|Rep:
           Dehydrogenase, E2 component, acyltransferase - Coxiella
           burnetii
          Length = 378

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 26/84 (30%), Positives = 46/84 (54%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL D+GEG+ +  I+EW++ VGD V+    +  +++ KA V + S   G I +L+ ++ 
Sbjct: 4   FKLPDLGEGLPDATIREWYIAVGDEVKIDQPLVAMETAKALVDVPSPLAGKIEKLFGEVG 63

Query: 575 QTALVGQPLVDIDVQDSENDGKPT 646
                G PL+  + +    + K T
Sbjct: 64  DVIETGSPLIGFEGEAETEEPKDT 87


>UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1;
           Symbiobacterium thermophilum|Rep: Pyruvate dehydrogenase
           E2 - Symbiobacterium thermophilum
          Length = 450

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 27/55 (49%), Positives = 35/55 (63%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           FKL D+GEG+ E  +  W VK GD V +   I EVQ+DKA V ITS  +G + +L
Sbjct: 5   FKLPDVGEGLHEAELLRWLVKEGDTVTEDQPIMEVQTDKATVEITSPVNGRVVKL 59


>UniRef50_A0JZU9 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=2; Micrococcineae|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Arthrobacter sp. (strain FB24)
          Length = 518

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 27/72 (37%), Positives = 42/72 (58%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ E  +  W V VGD ++    I EV++ K+ V + S Y G +  L+ +  
Sbjct: 7   FLLPDLGEGLTEAELVNWLVAVGDEIRVDQPIAEVETAKSMVEVPSPYAGTVAVLHGEPG 66

Query: 575 QTALVGQPLVDI 610
           QT  VG+PL+ +
Sbjct: 67  QTLDVGKPLISV 78


>UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2
           component PdhC; n=3; Mycobacterium|Rep: Dihydrolipoamide
           S-acetyltransferase E2 component PdhC - Mycobacterium
           ulcerans (strain Agy99)
          Length = 389

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/78 (38%), Positives = 43/78 (55%)
 Frame = +2

Query: 380 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           +++  F++ D+GEG+ EV +  W V VGD+V+    +C V++ KA V I S Y G I  L
Sbjct: 5   DRLKCFQVPDLGEGLEEVTVTSWAVAVGDDVELNQVLCSVETAKAEVEIPSPYAGRIVEL 64

Query: 560 YHDIDQTALVGQPLVDID 613
                    VG  LV ID
Sbjct: 65  GGAEGDVIKVGAALVRID 82


>UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid
           dehydrogenase E2; n=3; Staphylococcus|Rep:
           Branched-chain alpha-keto acid dehydrogenase E2 -
           Staphylococcus haemolyticus (strain JCSC1435)
          Length = 442

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 25/87 (28%), Positives = 47/87 (54%), Gaps = 2/87 (2%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  +GE + E  I++W + VGD V +++ +CEV +DK    + S   G IT +     +
Sbjct: 4   KMPKLGESVHEGTIEQWLISVGDYVDEYEPLCEVITDKVTAEVPSTVSGTITEILVSEGE 63

Query: 578 TALVGQPLVDIDVQDSEN--DGKPTDV 652
           T  +   +  I+  +++N  + K TD+
Sbjct: 64  TVQIDHVICKIETSETDNSTNTKNTDI 90


>UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.
           CcI3|Rep: Dehydrogenase subunit - Frankia sp. (strain
           CcI3)
          Length = 524

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 28/78 (35%), Positives = 42/78 (53%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F+L D+GEG+ E  I  W  +VGD V     + EV++ KA V + S + GI+   +    
Sbjct: 6   FRLPDLGEGLTEADIVRWLAQVGDTVTVNQPLVEVETAKAVVEVPSPFAGILVETHGAEG 65

Query: 575 QTALVGQPLVDIDVQDSE 628
            T  VG PL+ I   D++
Sbjct: 66  TTLAVGAPLLTIQTADTD 83


>UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2
           component, dihydrolipoamide acetyltransferase, putative;
           n=13; Mycobacterium|Rep: 2-oxoisovalerate dehydrogenase
           E2 component, dihydrolipoamide acetyltransferase,
           putative - Mycobacterium tuberculosis
          Length = 393

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 31/78 (39%), Positives = 43/78 (55%)
 Frame = +2

Query: 380 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           + I +F + D+GEG++EV +  W V VGD+V+    +C V++ KA V I S Y G I  L
Sbjct: 5   DSIRSFPVPDLGEGLQEVTVTCWSVAVGDDVEINQTLCSVETAKAEVEIPSPYAGRIVEL 64

Query: 560 YHDIDQTALVGQPLVDID 613
                    VG  LV ID
Sbjct: 65  GGAEGDVLKVGAELVRID 82


>UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2,
           dihydrolipoamide acetyltransferase; n=1; uncultured
           methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
           complex E2, dihydrolipoamide acetyltransferase -
           Uncultured methanogenic archaeon RC-I
          Length = 428

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL D+GEGI    IK+W VK GD V++ D I EV++DKA V + +   G +  +     
Sbjct: 5   FKLPDLGEGITSGEIKKWNVKKGDKVEEDDPIAEVETDKAVVELPAPVSGTVEDIKFKEG 64

Query: 575 QTALVGQPLVDIDVQDSENDG--KPTDVAPDKPVAE 676
               VG  +  I  +  E      P + AP  PV E
Sbjct: 65  DMVPVGSVIAVIREEGEETKAPPPPQEKAP-SPVQE 99


>UniRef50_A6FIQ1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
           complex dihydrolipoamideacyltransferase (E2) component;
           n=1; Moritella sp. PE36|Rep: Pyruvate/2-oxoglutarate
           dehydrogenase complex dihydrolipoamideacyltransferase
           (E2) component - Moritella sp. PE36
          Length = 396

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 33/91 (36%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL D+GEG+ E  I EWF+K GD V     +  +++ KA V I    + I+ +LY +  
Sbjct: 4   FKLPDLGEGLPEAEIVEWFIKPGDVVAADQLMVSMETAKAIVEIPCPENAIVVKLYGESG 63

Query: 575 QTALVGQPLVDI----DVQDSENDGKPTDVA 655
                G PLV+     D   SEN    T+ A
Sbjct: 64  DIIHTGDPLVEFVEEGDAISSENGAATTNGA 94


>UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
           dihydrolipoamide succinyltransferase; n=11;
           Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
           subunit, dihydrolipoamide succinyltransferase -
           Magnetococcus sp. (strain MC-1)
          Length = 446

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 30/93 (32%), Positives = 46/93 (49%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  +GE + E  + +W  +VGD V   + + E+++DK  V + S   G+IT +Y  +D 
Sbjct: 6   KVPTLGESVTEATVVQWLKQVGDAVAVDEPLVELETDKVTVEMPSPVAGVITEIYAGVDA 65

Query: 578 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
              VG  L  +D Q     G      P KP AE
Sbjct: 66  DVEVGAVLCVVDAQ-----GSARVAVPAKPAAE 93


>UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2
           component, dihydrolipoamide succinyltransferase family
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           2-oxoglutarate dehydrogenase, E2 component,
           dihydrolipoamide succinyltransferase family protein -
           Tetrahymena thermophila SB210
          Length = 564

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
 Frame = +2

Query: 362 HTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD 541
           HTS A   I    +  +G+ I E  + +   KVGD V+  + +C V++DK  V I S   
Sbjct: 136 HTSKANFAIKTINVPSMGDSITEGQVHQMLKKVGDYVELDEVVCSVETDKTQVPIRSPEA 195

Query: 542 GIITRLYHDIDQTALVGQP--LVDIDVQDSENDGKPTDVA 655
           G+IT L+    +   VG+P  ++D D +  E   KP   A
Sbjct: 196 GVITELFAQEGENVNVGKPFFVLDTDGKKPEGAAKPAAAA 235


>UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex; n=4; Acholeplasmataceae|Rep:
           Dihydrolipoyllysine-residue acetyltransferase component
           of pyruvate dehydrogenase complex - Acholeplasma
           laidlawii
          Length = 544

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 29/73 (39%), Positives = 41/73 (56%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FK +DIGEGI E  + +W  KVGD V++ + +  V++DK    + S  DG I  L     
Sbjct: 4   FKFADIGEGIHEGTVLQWNFKVGDKVKEGETLVIVETDKVNAELPSPVDGTIVSLGAKEG 63

Query: 575 QTALVGQPLVDID 613
           +   VGQ +V ID
Sbjct: 64  EEIHVGQIIVTID 76



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 29/77 (37%), Positives = 42/77 (54%)
 Frame = +2

Query: 374 AVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIIT 553
           A   I  FK +DIGEGI E  I +W  KVGD V++ + +  V++DK    + S  DG I 
Sbjct: 109 ASGDIYDFKFADIGEGIHEGTILQWNFKVGDKVKEGETLVVVETDKVNAELPSPVDGTIL 168

Query: 554 RLYHDIDQTALVGQPLV 604
           +L     +   VG+ +V
Sbjct: 169 KLGKAEGEVIHVGETVV 185


>UniRef50_P37942 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-keto acid dehydrogenase complex (EC
           2.3.1.168) (Dihydrolipoyllysine-residue (2-
           methylpropanoyl)transferase); n=37; Bacillales|Rep:
           Lipoamide acyltransferase component of branched-chain
           alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
           (Dihydrolipoyllysine-residue (2-
           methylpropanoyl)transferase) - Bacillus subtilis
          Length = 424

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 28/91 (30%), Positives = 46/91 (50%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           +  +GE + E  I +W V  GD V ++D I EV +DK    + S + G IT L  +  QT
Sbjct: 8   MPQLGESVTEGTISKWLVAPGDKVNKYDPIAEVMTDKVNAEVPSSFTGTITELVGEEGQT 67

Query: 581 ALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
             VG+ +  I+ + +     P +   ++P A
Sbjct: 68  LQVGEMICKIETEGA----NPAEQKQEQPAA 94


>UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase
           component of pyruvate dehydrogenase complex; n=1;
           Propionibacterium acnes|Rep: Dihydrolipoamide
           acetyltransferase component of pyruvate dehydrogenase
           complex - Propionibacterium acnes
          Length = 469

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 27/71 (38%), Positives = 41/71 (57%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           + D GEG+ E  +  W V  GD V+  D +CEV++ K+ V + S + G + +L  +  +T
Sbjct: 6   MPDPGEGLTEGEVVSWQVSPGDTVKINDVLCEVETAKSIVELPSPFAGTVAKLCAEPGET 65

Query: 581 ALVGQPLVDID 613
             VG PLV ID
Sbjct: 66  VAVGTPLVTID 76


>UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1;
           Pyrobaculum aerophilum|Rep: Pyruvate dehydrogenase E2 -
           Pyrobaculum aerophilum
          Length = 383

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 30/91 (32%), Positives = 50/91 (54%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FK  D+GEG+ E  + +W VK GD V++ D + +V ++KA VT+ +   G + ++     
Sbjct: 3   FKFPDLGEGLVEGEVIKWHVKEGDFVKEGDPLVDVMTEKATVTLPAPTTGRVVKILVREG 62

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDVAPDKP 667
           +   VGQ L  I+  +    G  T+ AP +P
Sbjct: 63  EVVKVGQTLCVIEPAEGPAAGPQTE-APARP 92


>UniRef50_UPI00005103B2 Cluster: COG0508: Pyruvate/2-oxoglutarate
           dehydrogenase complex, dihydrolipoamide acyltransferase
           (E2) component, and related enzymes; n=1; Brevibacterium
           linens BL2|Rep: COG0508: Pyruvate/2-oxoglutarate
           dehydrogenase complex, dihydrolipoamide acyltransferase
           (E2) component, and related enzymes - Brevibacterium
           linens BL2
          Length = 399

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 27/78 (34%), Positives = 41/78 (52%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ E  +  W V++GD V     + EV+S K+ V +   Y G I  L+ +  
Sbjct: 12  FILPDLGEGLTEAELISWKVEIGDEVHVDQMVVEVESAKSVVELPCPYAGRIVSLHANAG 71

Query: 575 QTALVGQPLVDIDVQDSE 628
            T   GQPL+ +    +E
Sbjct: 72  DTVSAGQPLLSVAEASAE 89


>UniRef50_UPI000038E473 Cluster: hypothetical protein Faci_03000379;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03000379 - Ferroplasma acidarmanus fer1
          Length = 78

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 17/66 (25%), Positives = 43/66 (65%)
 Frame = +2

Query: 416 EGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQ 595
           +G+ + +I +W+VKVGD++++   +C++ + K  V +  +  G +T+++ DI+   + G 
Sbjct: 12  QGLGKAIITQWYVKVGDSIKEDTPVCQIMAGKVTVEVEGKAKGKVTKIFRDINAEIVPGD 71

Query: 596 PLVDID 613
            L++++
Sbjct: 72  DLLEVE 77


>UniRef50_Q5ZV80 Cluster: Dihydrolipoamide acetyltransferase; n=5;
           Legionellales|Rep: Dihydrolipoamide acetyltransferase -
           Legionella pneumophila subsp. pneumophila (strain
           Philadelphia 1 /ATCC 33152 / DSM 7513)
          Length = 370

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 26/70 (37%), Positives = 37/70 (52%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ +  I EWFVK GD V+    +  +++ KA V +     G I +LY    
Sbjct: 4   FNLPDLGEGLPDAEIHEWFVKEGDTVKADQPLVSMETAKAVVDVPCPQSGTIAKLYGKPG 63

Query: 575 QTALVGQPLV 604
                G+PLV
Sbjct: 64  DVIKTGEPLV 73


>UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue
           acetyltransferase component e2 of pyruvate dehydrogenase
           protein; n=1; Spiroplasma citri|Rep: Putative
           dihydrolipoyllysine-residue acetyltransferase component
           e2 of pyruvate dehydrogenase protein - Spiroplasma citri
          Length = 427

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 28/94 (29%), Positives = 50/94 (53%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           +V FK +DIGEG+ E  + +  ++VGD ++    +  V++DK    I +  DGI++++  
Sbjct: 1   MVKFKFADIGEGLTEGKVAKIMIEVGDKIKDGVEMFAVETDKVNTEIYAPCDGIVSKINM 60

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKP 667
            +  T  VG  +V+ID  D      P     ++P
Sbjct: 61  AVGDTIYVGDVVVEID--DGTAGDSPAPATSEQP 92


>UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase
           component of pyruvate dehydrogenase complex; n=2;
           Thermoplasmatales|Rep: Dihydrolipoamide
           acetyltransferase component of pyruvate dehydrogenase
           complex - Picrophilus torridus
          Length = 386

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 26/79 (32%), Positives = 41/79 (51%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  IGEG+ E  I +W VK GD +++   I E+ +DK  + I S   G + +L     +
Sbjct: 5   KVPPIGEGVSEGEIVKWNVKEGDTIEKDQEIVEIMTDKITIKIPSPVSGKVLKLIEPEGK 64

Query: 578 TALVGQPLVDIDVQDSEND 634
           T  VG  +  ID Q+   +
Sbjct: 65  TVKVGDSIATIDSQEGNEE 83


>UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep:
           AceF - Mycoplasma gallisepticum
          Length = 440

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 22/70 (31%), Positives = 43/70 (61%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           +K +D+GEG+ E V+ + +VKVGD +++ D +  V++DK    + +   G +T +   + 
Sbjct: 4   YKFTDVGEGLHEGVVAQIYVKVGDTIKEGDPMFSVETDKVTTDLPAPEGGKVTAILASVG 63

Query: 575 QTALVGQPLV 604
           QT  VG+ ++
Sbjct: 64  QTVHVGEVML 73


>UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic domain
           of components of various dehydrogenase complexes:E3
           binding; n=2; Frankia|Rep: Biotin/lipoyl
           attachment:Catalytic domain of components of various
           dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
          Length = 475

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 29/94 (30%), Positives = 46/94 (48%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           ++ F L D+GEG+    I  W V +GD +     + EV++ KA V +   + G++T L  
Sbjct: 4   VLEFALPDLGEGLTSAEIVRWMVGIGDVIVVDQPVAEVETAKAVVEVPCPHAGVVTALAG 63

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKP 667
                  VG PL+ + V +     +P D  PD P
Sbjct: 64  PPGTAVPVGTPLITVTVDEPAE--QPAD-GPDGP 94


>UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex
           dihydrolipoamide acetyltransferase; n=2;
           Cystobacterineae|Rep: Pyruvate dehydrogenase complex
           dihydrolipoamide acetyltransferase - Stigmatella
           aurantiaca DW4/3-1
          Length = 533

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
 Frame = +2

Query: 422 IREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPL 601
           ++E  + +W  KVGD +   + I EV++DK+ + + +  DG + ++  D DQTA VG P+
Sbjct: 132 MKEGKVVKWLKKVGDKISSGEAIAEVETDKSNLEVEAYDDGTLAKILVDADQTAQVGAPI 191

Query: 602 VDIDVQDSE-NDGKPTDVAPDKPVA 673
             I  +  + +   P   AP  P A
Sbjct: 192 AYIAGKGGKVSVAAPAPAAPSAPAA 216



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/84 (27%), Positives = 42/84 (50%)
 Frame = +2

Query: 422 IREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPL 601
           ++E  + +W  KVGD V   D I EV++DK+ + + +  DG++ ++       A VG P+
Sbjct: 14  MKEGKLVKWLKKVGDKVSSGDAIAEVETDKSNLEVEAYDDGVLLQIVVAEGDLAQVGAPI 73

Query: 602 VDIDVQDSENDGKPTDVAPDKPVA 673
             +  +  + +      AP K  A
Sbjct: 74  AYVGEKGEKVEAGSKPAAPAKAEA 97


>UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase; n=3; Actinomycetales|Rep:
           Dihydrolipoyllysine-residue succinyltransferase -
           Rhodococcus sp. (strain RHA1)
          Length = 417

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 25/72 (34%), Positives = 40/72 (55%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F+L D+GEG+ E  +  W V+VG  ++    I EV++ KA V + S Y G++  L     
Sbjct: 5   FRLPDLGEGLTEAELVSWAVEVGQTIELNQVIGEVETAKALVELPSPYAGVVEELLVPAG 64

Query: 575 QTALVGQPLVDI 610
            T  VG P++ +
Sbjct: 65  ATVPVGTPIIRV 76


>UniRef50_Q8PQ85 Cluster: Dihydrolipoamide acyltransferase; n=7;
           Xanthomonas|Rep: Dihydrolipoamide acyltransferase -
           Xanthomonas axonopodis pv. citri
          Length = 505

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 25/78 (32%), Positives = 40/78 (51%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ +  I EWFVK GD V+  D +  +++ KA V + S + G + +L     
Sbjct: 7   FHLPDLGEGLPDATIVEWFVKEGDTVRLDDPLVSMETAKAVVEVPSPFSGTVVKLAGAAG 66

Query: 575 QTALVGQPLVDIDVQDSE 628
              + G  L    +  S+
Sbjct: 67  DVIVTGSVLAQFALDASQ 84


>UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
           Halobacterium salinarum|Rep: Dihydrolipoamide
           S-acetyltransferase - Halobacterium salinarium
           (Halobacterium halobium)
          Length = 478

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 29/85 (34%), Positives = 40/85 (47%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ E  +  W V  GD V +   + EV++DKA V + +  DG +  L+    
Sbjct: 5   FTLPDVGEGVAEGELVRWLVDEGDTVTEDQPVAEVETDKAQVEVPAPVDGTVQELHWAEG 64

Query: 575 QTALVGQPLVDIDVQDSENDGKPTD 649
               VG   V  DV D E      D
Sbjct: 65  DVVPVGDLFVTFDV-DGEASATADD 88


>UniRef50_A4WK39 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=2; Pyrobaculum|Rep: Catalytic
           domain of components of various dehydrogenase complexes
           - Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
          Length = 408

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 26/76 (34%), Positives = 45/76 (59%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           ++ FK  D+GEG+ E  I +W VK GD V++ D + +V ++KA VT+ +   G + +++ 
Sbjct: 1   MIEFKFPDLGEGLVEGEIVKWHVKEGDFVKEGDPLVDVMTEKANVTLPAPATGKVVKIFA 60

Query: 566 DIDQTALVGQPLVDID 613
              +   VGQ L  I+
Sbjct: 61  KEGEIVKVGQVLCVIE 76


>UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex; n=2; Mycoplasma|Rep:
           Dihydrolipoyllysine-residue acetyltransferase component
           of pyruvate dehydrogenase complex - Mycoplasma
           pneumoniae
          Length = 402

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 24/73 (32%), Positives = 41/73 (56%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FK +D+GEG+ E  + E   KVGD ++  + +  V++DK    + S Y G+IT +  ++ 
Sbjct: 5   FKFTDVGEGLHEGKVTEILKKVGDTIKVDEALFVVETDKVTTELPSPYAGVITAITTNVG 64

Query: 575 QTALVGQPLVDID 613
               +GQ +  ID
Sbjct: 65  DVVHIGQVMAVID 77


>UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4;
           Bacillaceae|Rep: Pyruvate dehydrogenase E2 -
           Oceanobacillus iheyensis
          Length = 420

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 27/89 (30%), Positives = 49/89 (55%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           +V  KL DIGEG+ E  I  +F++ GD V++   I E+Q++K    IT+   G +  ++ 
Sbjct: 1   MVEVKLHDIGEGMTEGDILTYFIQEGDQVEEDQPIVEMQTEKMVAEITAPAKGTVKEIFI 60

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTDV 652
               T  VG  ++ I+ +D+    K +++
Sbjct: 61  AEGTTISVGTTIMTIESEDAMEKTKSSEI 89


>UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransferase
           component; n=1; marine actinobacterium PHSC20C1|Rep:
           Putative dihydrolipoamide acyltransferase component -
           marine actinobacterium PHSC20C1
          Length = 480

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 29/75 (38%), Positives = 42/75 (56%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ E  I EW V VGD V     I EV++ KA V++ S   G I+ L+ +  
Sbjct: 6   FALPDLGEGLTESEIVEWHVAVGDMVTLNQPIAEVETAKAIVSLPSPVAGKISALHAEPG 65

Query: 575 QTALVGQPLVDIDVQ 619
            T  VG  +V  +++
Sbjct: 66  ATVSVGTRIVTFELE 80


>UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4;
           Actinomycetales|Rep: Dehydrogenase subunit - Frankia sp.
           (strain CcI3)
          Length = 430

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 25/76 (32%), Positives = 39/76 (51%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+    +  W V VGD +     + EV++ KA V +   Y G++T L     
Sbjct: 7   FPLPDLGEGLTSAEVVRWLVGVGDVITVDQPVAEVETAKAVVEVPCPYAGVVTSLAGLAG 66

Query: 575 QTALVGQPLVDIDVQD 622
            +  VG PL+ + V +
Sbjct: 67  TSVPVGTPLITVAVSE 82


>UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n=3;
           Trichocomaceae|Rep: Dihydrolipoamide succinyltransferase
           - Aspergillus oryzae
          Length = 448

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 35/115 (30%), Positives = 61/115 (53%), Gaps = 3/115 (2%)
 Frame = +2

Query: 341 SKELRHFHTS--HAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDK 511
           S +LR F  S  HA   KI+   +  + E I E V+  +  +VGD V+Q + +  +++DK
Sbjct: 52  SLQLRQFSASALHAAETKIIC--VPSMAESISEGVLSTFNRQVGDYVEQDEEVASIETDK 109

Query: 512 AAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
             V + +   G+IT+L  +   T  VGQ +++I +++ +     T  +P  P AE
Sbjct: 110 IDVAVNAPQSGMITKLIVNEGDTVTVGQAVIEISLEERDT----TSQSPLPPQAE 160


>UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex; n=35; Bacillales|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex -
           Staphylococcus saprophyticus subsp. saprophyticus
           (strain ATCC 15305 /DSM 20229)
          Length = 424

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 30/92 (32%), Positives = 46/92 (50%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+ ++ E I E  I EW  +VGD+V + + I E+++DK  V + S   G++  L  +   
Sbjct: 5   KVPELAESITEGTIAEWLKQVGDSVDKGEAIVELETDKVNVEVVSEEAGVLQELLANEGD 64

Query: 578 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
           T  VGQ +  +     E  G  T  AP K  A
Sbjct: 65  TVEVGQAIAVV----GEGSGNNTSEAPAKQEA 92


>UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E2
           component of the pyruvate dehydrogenase complex; n=2;
           Moraxellaceae|Rep: Dihydrolipoamide S-acetyltransferase,
           E2 component of the pyruvate dehydrogenase complex -
           Acinetobacter sp. (strain ADP1)
          Length = 661

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/120 (24%), Positives = 60/120 (50%)
 Frame = +2

Query: 272 KVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWF 451
           K  ++SA   +++  +TP+ +   +E +   ++ A + +V  ++ DIG  + +  + E  
Sbjct: 80  KTESESAPAQTEVKAETPVEQVAPQETKPATSTSAASSVVEVQVPDIG--VEKATVAELL 137

Query: 452 VKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSEN 631
           V VGD + + D++  ++SDKA+V + S   G I  +      T   G  L+ +    + N
Sbjct: 138 VSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDTIQEGVLLLKVKTAGASN 197



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/92 (26%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
 Frame = +2

Query: 419 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 598
           G+ +  + E  VKVGD + + D++  ++SDKA+V + S   G++  +   +      G  
Sbjct: 9   GVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLGDEVSEGTT 68

Query: 599 LVDIDVQD----SENDGKP--TDVAPDKPVAE 676
           L++++  D    +E++  P  T+V  + PV +
Sbjct: 69  LIELESGDNTDKTESESAPAQTEVKAETPVEQ 100



 Score = 41.1 bits (92), Expect = 0.024
 Identities = 22/79 (27%), Positives = 38/79 (48%)
 Frame = +2

Query: 419 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 598
           G+ +  + E  V VGD + + ++I  V+SDKA V + S   GI+  ++    Q    G  
Sbjct: 242 GVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDVKEGIL 301

Query: 599 LVDIDVQDSENDGKPTDVA 655
           LV ++ + +        VA
Sbjct: 302 LVTVEAEGAVASAPKAPVA 320


>UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, E2
           component, dihydrolipoamide acetyltransferase; n=1;
           Plesiocystis pacifica SIR-1|Rep: Alpha keto acid
           dehydrogenase complex, E2 component, dihydrolipoamide
           acetyltransferase - Plesiocystis pacifica SIR-1
          Length = 435

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           +V FKL +IGEG+ E  I +W +  G++    D + EV +DKA + I + +DG++     
Sbjct: 1   MVEFKLPEIGEGVIEGEIVQWLIAPGNSFATNDGLVEVMTDKATIEIPAPFDGVLREQRA 60

Query: 566 DIDQTALVGQPLVDID--VQDSENDGKPTDVAPDKPVA 673
                  VG  +  ++     S     P   AP  P A
Sbjct: 61  AEGDVCAVGSVIAILEEGAAASPEAPAPAAAAPATPAA 98


>UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-keto acid dehydrogenase complex;
           n=13; Bacteroidetes|Rep: Lipoamide acyltransferase
           component of branched-chain alpha-keto acid
           dehydrogenase complex - Robiginitalea biformata HTCC2501
          Length = 476

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           KL  +GE + E  +  W  +VGD ++  + + E+ +DK    + S  DG++     ++D 
Sbjct: 7   KLPQMGESVAEATLTSWLKEVGDAIEADEAVFEIATDKVDSEVPSEVDGVLVEKRFEVDD 66

Query: 578 TALVGQPLVDIDV---QDSENDGKPTDVAPD 661
              VGQ +  I++    D  + G+    +PD
Sbjct: 67  VVKVGQVVAVIELNGESDQPDAGREAAGSPD 97


>UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex; n=12; Bacteria|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex -
           Mycobacterium bovis
          Length = 553

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 29/92 (31%), Positives = 44/92 (47%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           + ++GE + E  +  W  K+GD+VQ  + + EV +DK    I S   G++  +  D D T
Sbjct: 126 MPELGESVTEGTVIRWLKKIGDSVQVDEPLVEVSTDKVDTEIPSPVAGVLVSISADEDAT 185

Query: 581 ALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
             VG  L  I V  ++    P      KPV E
Sbjct: 186 VPVGGELARIGVA-ADIGAAPAPKPAPKPVPE 216



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +GE + E  +  W  + GD V+  + + EV +DK    I S   G++T++    D T  V
Sbjct: 10  LGESVTEGTVTRWLKQEGDTVELDEPLVEVSTDKVDTEIPSPAAGVLTKIIAQEDDTVEV 69

Query: 590 GQPLVDIDVQDSENDGKPTDVAPDK-PVAE 676
           G  L  I   D+++ G+    AP+K P A+
Sbjct: 70  GGELAVIG--DAKDAGEAAAPAPEKVPAAQ 97


>UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1;
           Bdellovibrio bacteriovorus|Rep: Pyruvate dehydrogenase
           E2 - Bdellovibrio bacteriovorus
          Length = 543

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 26/78 (33%), Positives = 39/78 (50%)
 Frame = +2

Query: 380 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           N     KL ++GEG+ E  + +W VK GD V+    I EV +DKA V + S   G++  L
Sbjct: 9   NMATDVKLPELGEGVTEGELVKWLVKPGDAVKADQAIAEVLTDKATVEVPSPVAGVVKDL 68

Query: 560 YHDIDQTALVGQPLVDID 613
                    VG  ++ +D
Sbjct: 69  KFKSGDVVKVGATMITLD 86



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/72 (31%), Positives = 39/72 (54%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           KL ++GEG+ E  + +W VK GD+V+    I EV +DKA V + +   G++  L      
Sbjct: 123 KLPELGEGVTEGELVKWLVKPGDSVKADQAIAEVLTDKATVEVPTPVAGVVKELKFKSGD 182

Query: 578 TALVGQPLVDID 613
              VG  ++ ++
Sbjct: 183 VVKVGSTMIILE 194


>UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2
           component, dihydrolipoamide acetyltransferase; n=2;
           Desulfotalea psychrophila|Rep: Probable pyruvate
           dehydrogenase, E2 component, dihydrolipoamide
           acetyltransferase - Desulfotalea psychrophila
          Length = 397

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 29/92 (31%), Positives = 47/92 (51%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F++  +G  ++E  + EW VK+GD V++ D I EV++ K  + I    DG+I ++     
Sbjct: 4   FRMPSLGADMKEGRLVEWKVKLGDQVKRGDIIAEVETAKGVIEIEVFTDGVIEQILVQRG 63

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPV 670
           +   VG  L  I     E    P + AP +PV
Sbjct: 64  EKVPVGTVLATIRTA-GEQGKVPGEAAPPEPV 94


>UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3;
           Lactobacillales|Rep: Dihydrolipoamide acyltransferase -
           Enterococcus faecalis (Streptococcus faecalis)
          Length = 432

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 23/89 (25%), Positives = 46/89 (51%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  +GE + E  I +W VK GD+V+++D + EV SDK    + S ++    R+      
Sbjct: 7   KMPHLGESVTEAAIVQWLVKPGDSVKRYDPLMEVVSDKVTTEVPSDFEWCSKRISDFSRY 66

Query: 578 TALVGQPLVDIDVQDSENDGKPTDVAPDK 664
              +G  ++ ++ +++    +   +AP K
Sbjct: 67  RVPIGTAVMTLETEETTEKTEVATLAPVK 95


>UniRef50_Q7NLM9 Cluster: Gll1092 protein; n=1; Gloeobacter
           violaceus|Rep: Gll1092 protein - Gloeobacter violaceus
          Length = 384

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 22/75 (29%), Positives = 44/75 (58%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I   K+  +GEG++EV+I     + G+++++ + I  +++DKA + + S Y+G+I     
Sbjct: 3   ITEIKIPQLGEGLQEVLIDRLLKRSGEHIKRDEAIYVIETDKALMDVESPYEGVIQEWLV 62

Query: 566 DIDQTALVGQPLVDI 610
           + +   LVG P+  I
Sbjct: 63  EENDVVLVGSPVARI 77


>UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component
           dihydrolipoamide dehydrogenase; n=2; Bacteria|Rep:
           Pyruvate dehydrogenase E3 component dihydrolipoamide
           dehydrogenase - Mycoplasma mobile
          Length = 600

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FK +DIGEG+ E ++ E + K GD V++ + +  V++DK    I S   G I ++     
Sbjct: 4   FKFADIGEGLHEGLVAEIYKKEGDMVKEGEALFSVETDKVTSDIPSPATGKIVKVAMAQG 63

Query: 575 QTALVGQPLVDIDVQDSEN--DGKPTDVAPDKP 667
            T  VGQ +  ID   S    + KP ++  + P
Sbjct: 64  DTIHVGQEIYYIDDGSSSQSIEVKPAEIKAEAP 96


>UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme
           complex, dihydrolipoamide acetyltransferase component;
           n=16; Proteobacteria|Rep: Pyruvate dehydrogenase
           multienzyme complex, dihydrolipoamide acetyltransferase
           component - Azoarcus sp. (strain EbN1) (Aromatoleum
           aromaticum (strain EbN1))
          Length = 583

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 24/89 (26%), Positives = 48/89 (53%)
 Frame = +2

Query: 377 VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR 556
           +++++  K+ DIG+   +V + E FVK GD ++  D I  ++SDKA + + S   G++  
Sbjct: 1   MSELIEVKVPDIGD-YADVPVIELFVKPGDTIKVEDPIATLESDKATMDVPSTAAGVVRE 59

Query: 557 LYHDIDQTALVGQPLVDIDVQDSENDGKP 643
           +   +      G+ L+ ++   +EN   P
Sbjct: 60  VLVQVGDRVAEGKVLIKVEAAGAENTAAP 88



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 22/72 (30%), Positives = 40/72 (55%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           ++ DIG+   +V + E FVKVGD ++  D+I  ++SDKA + + S   G++  +   +  
Sbjct: 144 RVPDIGD-FSDVPVIELFVKVGDTIKVEDSIATLESDKATMDVPSSAAGVVREVKIKVGD 202

Query: 578 TALVGQPLVDID 613
               G  L+ +D
Sbjct: 203 RVSEGAVLIVVD 214


>UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2
           component, dihydrolipoamide succinyltransferase; n=1;
           Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate
           dehydrogenase, E2 component, dihydrolipoamide
           succinyltransferase - Dichelobacter nodosus (strain
           VCS1703A)
          Length = 341

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 22/92 (23%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  + E + + ++  W   VGD V+Q +N+ ++++DK  + + +   GII  +  +   
Sbjct: 6   KIPTLPESVSDAILVNWHKSVGDFVEQGENLIDLETDKVMLEMPAPVSGIIAEILQEDGM 65

Query: 578 TALVGQPLVDIDVQDSENDGKPT-DVAPDKPV 670
           T + GQ +  I+ Q  +++  P   +  ++PV
Sbjct: 66  TVISGQVIARIEEQKQQHEVPPAKKITIEEPV 97


>UniRef50_Q5BXT9 Cluster: SJCHGC06137 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC06137 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 185

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
 Frame = +2

Query: 353 RHF-HTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 529
           RHF HTS  +   V  K+  +   + +  I  W    G++V   D +CEVQ+DKA ++  
Sbjct: 14  RHFIHTSRRIQFPVNIKMPSLSPTMSDGTIVNWLKNEGEDVTAGDVLCEVQTDKAVISFE 73

Query: 530 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSEN 631
           S  DG++ ++      +++    L+ +     EN
Sbjct: 74  SDEDGVLAKILAPAGSSSIKVGGLIAVLATPGEN 107


>UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase
           component E2; n=2; Tropheryma whipplei|Rep:
           Dihydrolipoamide succinyltransferase component E2 -
           Tropheryma whipplei (strain Twist) (Whipple's bacillus)
          Length = 461

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L  +GE + E VI  W  + GD V+  + + EV +DK    + S   GI+  +    D
Sbjct: 5   FILPALGESVSECVITRWLKEAGDRVEVDEPLVEVSTDKVDTELPSTLTGILEEILVQRD 64

Query: 575 QTALVGQPLVDIDVQDSE 628
           +TA  GQ L  I V   E
Sbjct: 65  ETAKPGQILARIAVDKDE 82


>UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2
           component dihydrolipoamide acetyltransferase; n=1;
           Psychromonas ingrahamii 37|Rep: Pyruvate dehydrogenase
           complex, E2 component dihydrolipoamide acetyltransferase
           - Psychromonas ingrahamii (strain 37)
          Length = 451

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+   G  +++  + +W VK GD++++ D +  +++ K A+ +    D +I  L     Q
Sbjct: 9   KMPSFGSDMKKGTLVQWLVKEGDHIKRGDVVAVIETHKGAIDLDLFEDALIISLLIKEGQ 68

Query: 578 TALVGQPLVDI-DVQDSENDGKP-TDVAPDKP 667
              VG+P+  +   +DSEN   P TDVA  +P
Sbjct: 69  QIAVGEPIARLSSTKDSENAPLPQTDVADIEP 100


>UniRef50_Q2UDD6 Cluster: Predicted protein; n=1; Aspergillus
           oryzae|Rep: Predicted protein - Aspergillus oryzae
          Length = 149

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 22/76 (28%), Positives = 44/76 (57%)
 Frame = +2

Query: 413 GEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVG 592
           GE I E  ++ +  KVGD V+Q D +  ++++K A+ + +   G+I +++ +   T  +G
Sbjct: 73  GESIDEAKLQSFNRKVGDYVKQDDVLAVIETEKVALEVYAPETGVIQQVFVEEGDTVTIG 132

Query: 593 QPLVDIDVQDSENDGK 640
           Q + +I ++    DGK
Sbjct: 133 QAIAEITIKSKPGDGK 148


>UniRef50_O94709 Cluster: Probable pyruvate dehydrogenase protein X
           component, mitochondrial precursor; n=1;
           Schizosaccharomyces pombe|Rep: Probable pyruvate
           dehydrogenase protein X component, mitochondrial
           precursor - Schizosaccharomyces pombe (Fission yeast)
          Length = 456

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 32/115 (27%), Positives = 64/115 (55%), Gaps = 1/115 (0%)
 Frame = +2

Query: 335 SLSKELRHFHTSHAVNKIVA-FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDK 511
           SLS + R+FH S A+N + + F++  +   + E  I +W  K GD+ +  D + EV++DK
Sbjct: 18  SLSVKQRYFHCS-ALNGVASMFRMPALSPTMEEGNITKWHFKEGDSFKSGDILLEVETDK 76

Query: 512 AAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
           A + +  + +GI+ ++  +      VG+ +    V D+E++ K  ++  D+  +E
Sbjct: 77  ATMDVEVQDNGILAKVLIEKGSNIPVGKNIA--IVADAEDNLKDLELPKDEASSE 129


>UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 370

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 23/80 (28%), Positives = 43/80 (53%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+ ++ E I E  +K+W  ++GD V+Q + I  +++DK  V + +   G I     + + 
Sbjct: 42  KVPEMAESISEGTLKQWSKQIGDFVEQDEEIATIETDKIDVAVNAPEAGTIKEFLANEED 101

Query: 578 TALVGQPLVDIDVQDSENDG 637
           T  VGQ LV +++  +   G
Sbjct: 102 TVTVGQDLVRLELGGAPEGG 121


>UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferase
           component of pyruvate dehydrogenase complex (E2)
           protein; n=1; Nitrosomonas europaea|Rep: AceF;
           dihydrolipoamide acetyltransferase component of pyruvate
           dehydrogenase complex (E2) protein - Nitrosomonas
           europaea
          Length = 453

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 27/84 (32%), Positives = 44/84 (52%)
 Frame = +2

Query: 407 DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTAL 586
           DIG+   ++ + E  VK GD+VQ  D +  ++SDKA V + S Y GII  +   +     
Sbjct: 13  DIGD-FEDIPVIEIMVKPGDSVQVEDPLIVLESDKATVEVPSPYSGIIREIRVQMGSKVS 71

Query: 587 VGQPLVDIDVQDSENDGKPTDVAP 658
               ++ ++V  +E+D K T   P
Sbjct: 72  KDSEILTMEVVSAESDNKTTSSQP 95


>UniRef50_Q7X2B2 Cluster: PdhC; n=1; Lactobacillus reuteri|Rep: PdhC
           - Lactobacillus reuteri
          Length = 285

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 30/86 (34%), Positives = 44/86 (51%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F+L ++GEG+ E  I  + VK GD V+  D + E+Q+DK+   + S   G I ++    D
Sbjct: 5   FRLPEMGEGLTEGDIASFLVKEGDQVKDGDPLVEIQTDKSTTQLVSPVAGTIKKIEAKED 64

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDV 652
                G  LV I   D   DG  T+V
Sbjct: 65  DHVEKGNDLVLI---DDGKDGVSTNV 87


>UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
           complex dihydrolipoamide acyltransferase (E2) component
           and related enzyme; n=1; Planctomyces maris DSM
           8797|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
           dihydrolipoamide acyltransferase (E2) component and
           related enzyme - Planctomyces maris DSM 8797
          Length = 449

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 5/99 (5%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL ++ EG+    + +  V VGD V+Q   + ++++DKA V + S Y G I  L     
Sbjct: 5   FKLPEVSEGVETADVGQISVAVGDTVEQGQVLMDIETDKAVVQLESPYSGTIEELKVSEG 64

Query: 575 QTALVGQPLVDI-----DVQDSENDGKPTDVAPDKPVAE 676
            +  +G  L+ I     D      + K  +   ++PVAE
Sbjct: 65  DSVSIGAVLLLINESNGDASAPAKEEKSAETKAEEPVAE 103


>UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex; n=1; Gramella forsetii KT0803|Rep:
           Dihydrolipoyllysine-residue acetyltransferase component
           of pyruvate dehydrogenase complex - Gramella forsetii
           (strain KT0803)
          Length = 507

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 24/79 (30%), Positives = 42/79 (53%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  I EG+    + E  VK GD++++  +I  V+SDKA+V I S   G +  +      
Sbjct: 6   KIPQIAEGVESATVTEVLVKEGDSIEKDQSIIAVESDKASVEIPSPQAGTVKSISVSEGD 65

Query: 578 TALVGQPLVDIDVQDSEND 634
              VG  +++++  D+E D
Sbjct: 66  EVEVGDVILELEEGDAEED 84


>UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex; n=5; Actinomycetales|Rep:
           Dihydrolipoyllysine-residue acetyltransferase component
           of pyruvate dehydrogenase complex - Leifsonia xyli
           subsp. xyli
          Length = 452

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 25/79 (31%), Positives = 43/79 (54%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ E  I  W V  GD+V     I E+++ K+ V + S ++G +  L     
Sbjct: 6   FLLPDVGEGLTEAEIVSWKVAPGDSVAVNQVIVEIETAKSLVELPSPFEGTVGELLVVEG 65

Query: 575 QTALVGQPLVDIDVQDSEN 631
           QT  VG P+  ++  ++++
Sbjct: 66  QTVEVGTPIFTVNGGEADH 84


>UniRef50_A1UIB1 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=4; Actinomycetales|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Mycobacterium sp. (strain KMS)
          Length = 629

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           V+ ++  +GE + E  +  W  + GD V+Q + + EV +DK    I S   G++ ++   
Sbjct: 21  VSVQMPALGESVTEGTVTRWLKQEGDTVEQDEPLLEVSTDKVDTEIPSPASGVLQKIVAQ 80

Query: 569 IDQTALVGQPLVDI-----DVQDSENDGKPTDVAPDKPVAE 676
            D T  VG  L  I     D  DS +D    +   ++P  E
Sbjct: 81  EDDTVEVGGELAVIGEGGEDSGDSSDDSSSDEDEDEEPAEE 121



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 26/92 (28%), Positives = 41/92 (44%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           + ++GE + E  +  W  KVGD+V+  + + EV +DK    I S   G +  +  + D T
Sbjct: 172 MPELGESVTEGTVTRWLKKVGDSVEVDEPLLEVSTDKVDTEIPSPVAGTLLEIIAEEDDT 231

Query: 581 ALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
             VG  L  I   D     +P      +P  E
Sbjct: 232 VEVGGELAKIGDADQAEAEEPEPEPEPEPEPE 263


>UniRef50_A1FTV4 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=2; Xanthomonadaceae|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Stenotrophomonas maltophilia R551-3
          Length = 546

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 20/55 (36%), Positives = 34/55 (61%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           F L D+GEG+ +  I EWFVK GD ++  + +  +++ KA V + S + G + +L
Sbjct: 91  FNLPDLGEGLPDATIVEWFVKEGDVIKLDEPLVSMETAKAVVEVPSPFSGTVLKL 145


>UniRef50_A0XBY6 Cluster: Biotin/lipoyl attachment domain-containing
           protein; n=1; Dinoroseobacter shibae DFL 12|Rep:
           Biotin/lipoyl attachment domain-containing protein -
           Dinoroseobacter shibae DFL 12
          Length = 398

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 25/88 (28%), Positives = 43/88 (48%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +GE + E  I +W V+ G + ++ D + EV++DK  V   +  DGI+            V
Sbjct: 4   LGETMEEATIADWLVQPGQSFKRGDPLLEVETDKTMVEYPALGDGILVETLVGPGDVVEV 63

Query: 590 GQPLVDIDVQDSENDGKPTDVAPDKPVA 673
           G P+  I+ +D+ +  +  D A   P A
Sbjct: 64  GTPIAVIETRDAWDSVEEPDAAASSPGA 91


>UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;
           n=2; Dictyostelium discoideum|Rep: Dihydrolipoamide
           S-succinyltransferase - Dictyostelium discoideum AX4
          Length = 439

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 32/130 (24%), Positives = 59/130 (45%)
 Frame = +2

Query: 221 VRRSVFQLRTVNRCRKIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFK 400
           V RS  +L   N    ++  T S+ +     +      + + + + F++S   N +V  K
Sbjct: 21  VVRSTSRLINNNSINTVRQFTSSSSSSFTSLFNNNNVNNTNIKYQRFYSS--ANDVV-IK 77

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           +  +G+ I E  I  W   VGD+V+  + +C +++DK  + I +   G I  L+    + 
Sbjct: 78  VPSMGDSISEGTIVAWTKNVGDSVRVDEVVCSIETDKVTIDINAPVSGTIVELFAKEGEN 137

Query: 581 ALVGQPLVDI 610
             VG  L  I
Sbjct: 138 VTVGNDLYKI 147


>UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG10947.1 - Gibberella zeae PH-1
          Length = 442

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 28/114 (24%), Positives = 49/114 (42%)
 Frame = +2

Query: 335 SLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKA 514
           ++  + R F  S  +N      +  + E I E  +     KVG+ V+Q + I  +++DK 
Sbjct: 37  AIDPQRRLFSNSGFLNGSYIVSVPPMAESITEGTLSSLSKKVGEAVEQDEEIASIETDKI 96

Query: 515 AVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
            V + +   G I   + +   T +VGQ L  I   +     K ++    KP  E
Sbjct: 97  DVLVNASEPGAIAEYFAEEGDTVVVGQDLARIVTGEDAGSAKKSEGGEQKPAKE 150


>UniRef50_Q7N5R0 Cluster: Similarities with dihydrolipoamide
           acyltransferase and succinyltransferase; n=1;
           Photorhabdus luminescens subsp. laumondii|Rep:
           Similarities with dihydrolipoamide acyltransferase and
           succinyltransferase - Photorhabdus luminescens subsp.
           laumondii
          Length = 521

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 28/86 (32%), Positives = 45/86 (52%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +GEG  EVVI +   +VGD+V++ + + E+++DKAA TI S  +GI+ +     +    V
Sbjct: 9   MGEGTTEVVIIQLLKQVGDHVKRDEPVYEMETDKAAFTIESDVEGILEKWLAAENDIIPV 68

Query: 590 GQPLVDIDVQDSENDGKPTDVAPDKP 667
           G P+  I       +  P   A   P
Sbjct: 69  GSPIAVIRAVGEMAEPSPVSEALTPP 94


>UniRef50_A5UTW4 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=5; Chloroflexi (class)|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Roseiflexus sp. RS-1
          Length = 434

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           L  IGE + E  I  W  +VGD V++++ + EV++DK +  +TS   G++  +      T
Sbjct: 7   LPQIGESMTEATIGRWLKRVGDRVERYEALVEVETDKVSTEVTSITSGVLLEIATPEGAT 66

Query: 581 ALVGQPLVDI 610
             VG  L  I
Sbjct: 67  VPVGALLARI 76


>UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex; n=7; Flavobacteria|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex -
           Gramella forsetii (strain KT0803)
          Length = 438

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/86 (34%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+   GE I EV I +W V+ GD V++   + EV SDKA + + +   GIIT    + D 
Sbjct: 6   KVPSPGESITEVEIAQWLVEDGDYVEKDQAVAEVDSDKATLELPAEASGIITFKAEEGD- 64

Query: 578 TALVGQP--LVDIDVQDSENDGKPTD 649
              VG+   L+D + +    DG   D
Sbjct: 65  LVQVGEVVCLIDTEAEKPGGDGGSDD 90


>UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X
           component, mitochondrial precursor; n=26; Amniota|Rep:
           Pyruvate dehydrogenase protein X component,
           mitochondrial precursor - Homo sapiens (Human)
          Length = 501

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/113 (27%), Positives = 57/113 (50%), Gaps = 5/113 (4%)
 Frame = +2

Query: 353 RHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 529
           R FH++  +    +   +  +   + E  I +W  K G+ V   D +CE+++DKA VT+ 
Sbjct: 44  RWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLD 103

Query: 530 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGK----PTDVAPDKPVAE 676
           +  DGI+ ++  +     +    L+ + V++ E D K    P DV P  PV++
Sbjct: 104 ASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGE-DWKHVEIPKDVGPPPPVSK 155


>UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex; n=7; Proteobacteria|Rep:
           Dihydrolipoyllysine-residue acetyltransferase component
           of pyruvate dehydrogenase complex - Pseudomonas
           aeruginosa
          Length = 547

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           ++ DIG G  EV+  E  VK GD V+   ++  ++SDKA++ I S   G++  +   +  
Sbjct: 6   RVPDIGNGEGEVI--ELLVKPGDKVEADQSLLTLESDKASMEIPSPKAGVVKSIKAKVGD 63

Query: 578 TALVGQPLVDIDVQDSENDGK-PTDVAPDKPVA 673
           T   G  +++++V+  E   +   + AP +P A
Sbjct: 64  TLKEGDEILELEVEGGEQPAEAKAEAAPAQPEA 96



 Score = 35.9 bits (79), Expect = 0.90
 Identities = 22/82 (26%), Positives = 40/82 (48%)
 Frame = +2

Query: 374 AVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIIT 553
           A   +   K+ DIG   +  VI E  VK GD V+   ++  ++SDKA++ I S   G++ 
Sbjct: 115 AAASVQDIKVPDIGSAGKANVI-EVMVKAGDTVEADQSLITLESDKASMEIPSPASGVVE 173

Query: 554 RLYHDIDQTALVGQPLVDIDVQ 619
            +   +      G  ++ + V+
Sbjct: 174 SVSIKVGDEVGTGDLILKLKVE 195


>UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex
           dihydrolipoamide acetyltransferase family protein; n=1;
           Tetrahymena thermophila SB210|Rep: pyruvate
           dehydrogenase complex dihydrolipoamide acetyltransferase
           family protein - Tetrahymena thermophila SB210
          Length = 646

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 7/118 (5%)
 Frame = +2

Query: 272 KVTTQSARNGSQLSYKTPL------NESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREV 433
           + +  + + G + S+K PL      ++SLS+ + +  +S+  +++VA  L  +   + E 
Sbjct: 38  RYSMSTVQKGKKTSFKAPLYQINFQSQSLSQNITYNFSSYPKHRLVA--LPALSPTMTEG 95

Query: 434 VIKEWFVKVGDNVQQFDNICEVQSDKAAV-TITSRYDGIITRLYHDIDQTALVGQPLV 604
            I  W +KVG  +Q+ DNI +VQ+DK +V  +     G + ++  +  +      P+V
Sbjct: 96  KIAAWHIKVGQKIQEGDNIFDVQTDKDSVPNVYQEETGFVAKILVNEGELIPANTPVV 153



 Score = 34.7 bits (76), Expect = 2.1
 Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
 Frame = +2

Query: 284 QSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVG 463
           Q A+   +     P  ++ +K      +  +  K     L  +   + E  I  + VKVG
Sbjct: 174 QKAQEAPKQEQPKPAAQTAAKPAPAASSGASFPKHNVVLLPALSPTMTEGKIASFHVKVG 233

Query: 464 DNVQQFDNICEVQSDKAAV-TITSRYDGIITRLYHDIDQTALVGQPLV 604
           D V + DNI +VQ+DK +V  I     G + ++     +T     P++
Sbjct: 234 DKVTEGDNIFDVQTDKDSVPNIYQEASGFVAKILVKEGETIPANHPVL 281


>UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-keto acid dehydrogenase complex;
           n=8; Bacteroidetes|Rep: Lipoamide acyltransferase
           component of branched-chain alpha-keto acid
           dehydrogenase complex - Bacteroides thetaiotaomicron
          Length = 456

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 27/90 (30%), Positives = 41/90 (45%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  +GE I E  I  W VKVGD +Q+ D + EV + K +  I S   G +  +      
Sbjct: 7   KMPKLGESITEGTIVSWSVKVGDVIQEDDVLFEVNTAKVSAEIPSPVAGKVVEILFKEGD 66

Query: 578 TALVGQPLVDIDVQDSENDGKPTDVAPDKP 667
           T  VG  +  +D+   E   + T    + P
Sbjct: 67  TVAVGTVVAVVDMGGEEASDEETASGKETP 96


>UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component
           dihydrolipoamide acetyltransferase; n=6; Mycoplasma|Rep:
           Pyruvate dehydrogenase E2 component dihydrolipoamide
           acetyltransferase - Mycoplasma mobile
          Length = 453

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 28/91 (30%), Positives = 45/91 (49%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FK +DIGEG+ E V+ E + K GD V++ + +  V++DK    I S   G I ++     
Sbjct: 4   FKFADIGEGLHEGVVAEIYKKEGDMVKEGEALFSVETDKVTSDIPSPVTGKIIKVAMFKG 63

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDVAPDKP 667
            T  VGQ +  I  +D  +      +  + P
Sbjct: 64  DTIHVGQEIYQI--EDGSSSSSSVGIKTEAP 92


>UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 component;
           n=5; Actinomycetales|Rep: 2-oxoglutarate dehydrogenase
           E2 component - Kineococcus radiotolerans SRS30216
          Length = 618

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 28/94 (29%), Positives = 42/94 (44%)
 Frame = +2

Query: 392 AFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDI 571
           A K+  +GE + E  +  W   VGD+V+  + + EV +DK    I S   G +  +    
Sbjct: 139 AVKMPALGESVTEGTVTRWLKAVGDSVEVDEPLLEVSTDKVDTEIPSPVAGTLLEILVGE 198

Query: 572 DQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
           D+TA VG  L  I    +     P   A + P A
Sbjct: 199 DETADVGADLARIGDASAAPSPAPAAPAQEAPAA 232



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/88 (29%), Positives = 37/88 (42%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +GE + E  +  W   VGD V+  + + EV +DK    I S   G +  +    D+TA V
Sbjct: 10  LGESVTEGTVTRWLKAVGDTVEVDEPLLEVSTDKVDTEIPSPVAGTLLEILVPEDETADV 69

Query: 590 GQPLVDIDVQDSENDGKPTDVAPDKPVA 673
           G  L  I     +  G P       P A
Sbjct: 70  GADLARIGDPSEQGGGSPAPQEQPAPAA 97


>UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3
           component of 3 enzyme complexes; n=1; Psychromonas
           ingrahamii 37|Rep: Dihydrolipoamide dehydrogenase E3
           component of 3 enzyme complexes - Psychromonas
           ingrahamii (strain 37)
          Length = 431

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 22/81 (27%), Positives = 45/81 (55%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           +  KL ++  G    VI  W V  GDN+++ D I EV++DKA + + S   G++ ++  D
Sbjct: 3   IEIKLPEVVSGFESGVIASWCVNEGDNIKKGDVIFEVETDKAVIEVESPGAGVLGKILVD 62

Query: 569 IDQTALVGQPLVDIDVQDSEN 631
            + + +    +V + + ++E+
Sbjct: 63  SNSSPVAVDTIVGMILLENED 83


>UniRef50_Q59RQ7 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 225

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 32/107 (29%), Positives = 54/107 (50%)
 Frame = -2

Query: 663 LSGATSVGFPSFSESCTSISTRGCPTRAV*SISWYSRVMIPSYRLVMVTAALSLCTSQML 484
           L+GA+    P    S +SI     PT  V S S  + V++P    +  T+ LS+    ++
Sbjct: 121 LAGASDADAPPAGASPSSILMISWPTSTVASTSTKNSVIVPDTGALTSTSILSVSMVAIV 180

Query: 483 SNC*TLSPTLTNHSLMTTSRIPSPISESLKATILLTA*LVWKCLNSL 343
           S+  T SPT    SL+  +++PS I  ++  T+  T+  +WK  N +
Sbjct: 181 SSWSTKSPT----SLLKAAKVPSVIDSAISGTLTETSAYLWKVKNGV 223


>UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex; n=95; Bacteria|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex -
           Bacillus subtilis
          Length = 417

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 26/87 (29%), Positives = 46/87 (52%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+ ++ E I E  I +W  + GD V+Q + + E+++DK  V +T+   G++  +  D   
Sbjct: 5   KVPELAESISEGTIAQWLKQPGDYVEQGEYLLELETDKVNVELTAEESGVLQEVLKDSGD 64

Query: 578 TALVGQPLVDIDVQDSENDGKPTDVAP 658
           T  VG+ +  I    SE  G+ +  AP
Sbjct: 65  TVQVGEIIGTI----SEGAGESSAPAP 87


>UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n=1;
           Mycobacterium leprae|Rep: Dihydrolipoamide
           succinyltransferase - Mycobacterium leprae
          Length = 530

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/72 (31%), Positives = 37/72 (51%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           + ++GE + E  +  W  K+GD+VQ  + + EV +DK    I S   G++  +  + D T
Sbjct: 123 MPELGESVTEGTVTRWLKKIGDSVQADEPLVEVSTDKVDTEIPSPVAGVLVSITTNEDTT 182

Query: 581 ALVGQPLVDIDV 616
             VG  L  I V
Sbjct: 183 VPVGGELARIGV 194



 Score = 41.9 bits (94), Expect = 0.014
 Identities = 21/67 (31%), Positives = 33/67 (49%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +GE + E  +  W  + GD V+  + + EV +DK    I S   G++T++    D T  V
Sbjct: 10  LGESVTEGTVTRWLKQEGDTVELDEPLVEVSTDKVDTEIPSPAAGVLTKIIAQEDDTVEV 69

Query: 590 GQPLVDI 610
           G  L  I
Sbjct: 70  GGELAVI 76


>UniRef50_A1SQB9 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=3; Actinomycetales|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 474

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 24/72 (33%), Positives = 40/72 (55%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           +KL D GEG+ E  I +W V VGD V+    + E+++ K+ V + S Y G ++ +     
Sbjct: 4   YKLPDPGEGLTEAEIVKWHVAVGDVVEINQVVVEIETAKSIVELPSPYAGEVSAILVAEG 63

Query: 575 QTALVGQPLVDI 610
           +   VG P++ I
Sbjct: 64  ELVPVGTPIIAI 75


>UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n=3;
           Geobacter|Rep: Dihydrolipoamide succinyltransferase -
           Geobacter metallireducens (strain GS-15 / ATCC 53774 /
           DSM 7210)
          Length = 418

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  +GE + E ++ +W  K G+ V++ + +CE+++DK  + I +  DG++T +  +   
Sbjct: 4   KVPSVGESVYEALVGKWLKKNGEAVRKDEPVCEIETDKITMEIDAGADGVLTIMVPE-GA 62

Query: 578 TALVGQPLVDIDVQDSE---NDGKPTDVAPDKP 667
           T  +G  +  I+    +     GK  +V P  P
Sbjct: 63  TVKIGSVIGIIEAGTGDRGPGTGKGKEVPPLSP 95


>UniRef50_A6Q9K5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
           complex, E2 component, dihydrolipoamide
           acetyltransferase; n=1; Sulfurovum sp. NBC37-1|Rep:
           Pyruvate/2-oxoglutarate dehydrogenase complex, E2
           component, dihydrolipoamide acetyltransferase -
           Sulfurovum sp. (strain NBC37-1)
          Length = 446

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 30/89 (33%), Positives = 42/89 (47%)
 Frame = +2

Query: 383 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 562
           K+V  +LSD    + E  + EW ++ GD V+  D I EV+SDKA + I     G +  L 
Sbjct: 4   KVVMPRLSD---SMDEGQLVEWKIRPGDVVRNGDVIAEVESDKAVMEIQIFKSGTVKELL 60

Query: 563 HDIDQTALVGQPLVDIDVQDSENDGKPTD 649
            D   T  VG P+  ID          T+
Sbjct: 61  IDAGSTVPVGTPMAVIDTDVGSGSSVKTE 89


>UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
           complex, E2 component, dihydrolipoamide
           acetyltransferase; n=1; Sulfurovum sp. NBC37-1|Rep:
           Pyruvate/2-oxoglutarate dehydrogenase complex, E2
           component, dihydrolipoamide acetyltransferase -
           Sulfurovum sp. (strain NBC37-1)
          Length = 410

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 23/72 (31%), Positives = 38/72 (52%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FK+  +G  +    + EW VK G+ V++   I EV+S+K  + +    DG++ RL  +  
Sbjct: 4   FKMPSLGADMESGTLMEWKVKEGEKVKKGQVIAEVESNKGVIEVEVFEDGVVDRLLVEPG 63

Query: 575 QTALVGQPLVDI 610
            T  VG P+  I
Sbjct: 64  TTCDVGTPIAVI 75


>UniRef50_A6PBA2 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=1; Shewanella sediminis
           HAW-EB3|Rep: Catalytic domain of components of various
           dehydrogenase complexes - Shewanella sediminis HAW-EB3
          Length = 377

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 24/86 (27%), Positives = 46/86 (53%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           +  +G  + E ++ EW VK GD V++ D I  +++ K A+ +   + G+I+ + H    T
Sbjct: 1   MPSLGADMTEGMLVEWLVKRGDPVKRGDIIAVIETQKGAIDMEVYHTGVISEILHQPVVT 60

Query: 581 ALVGQPLVDIDVQDSENDGKPTDVAP 658
             VG  +  ++ Q S+ +   T +AP
Sbjct: 61  LPVGTVMARVETQASDREVAAT-IAP 85


>UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component,
           dihydrolipoamideacetyltransferase; n=2;
           Planctomycetaceae|Rep: Pyruvate dehydrogenase, E2
           component, dihydrolipoamideacetyltransferase -
           Blastopirellula marina DSM 3645
          Length = 472

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           KL ++G+GI    I   +V  GD V +  NI E+++DKA V I +   G +T+++     
Sbjct: 6   KLPELGDGIDSGDILSVYVSEGDVVTKNQNILELETDKATVEIPTNVAGKVTKVHVKTGD 65

Query: 578 TALVGQPLVDIDVQD--SENDGKPTDVAPDK 664
              +G  L+ ++  +  ++ + KP   AP K
Sbjct: 66  AVPIGGALISVEASEGAAKEESKPAP-APKK 95


>UniRef50_Q38C09 Cluster: Dihydrolipoamide acetyltransferase,
           putative; n=1; Trypanosoma brucei|Rep: Dihydrolipoamide
           acetyltransferase, putative - Trypanosoma brucei
          Length = 260

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 24/73 (32%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
 Frame = +2

Query: 434 VIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD-GIITRLYHDIDQTALVGQPLVDI 610
           +I EW  KVGD V++ D  C +Q+DKA V  T+ +D G + +++    +T  V   +  +
Sbjct: 27  IIVEWKKKVGDLVKENDVFCTIQTDKAVVDFTNTFDAGYLGKIFRQNGETVAVASTIAAM 86

Query: 611 DVQDSENDGKPTD 649
            V++S++  K  D
Sbjct: 87  -VEESQDVAKLAD 98


>UniRef50_A6UDY3 Cluster: Biotin/lipoyl attachment domain-containing
           protein; n=1; Sinorhizobium medicae WSM419|Rep:
           Biotin/lipoyl attachment domain-containing protein -
           Sinorhizobium medicae WSM419
          Length = 437

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 22/73 (30%), Positives = 39/73 (53%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  +GE + E  I  W +K GD+ ++ D I E+++DK      +  DG +  +  +I  
Sbjct: 7   KMPRLGETMEEGKIVGWLIKPGDSFRRGDPIIEIETDKTIAEFPALGDGRLEEVLVEIGD 66

Query: 578 TALVGQPLVDIDV 616
              VG+PL  +D+
Sbjct: 67  MIEVGKPLARVDI 79


>UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex; n=2; Enterobacteriaceae|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex -
           Buchnera aphidicola subsp. Acyrthosiphon pisum
           (Acyrthosiphon pisumsymbiotic bacterium)
          Length = 420

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 21/77 (27%), Positives = 41/77 (53%)
 Frame = +2

Query: 383 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 562
           K +   + D+ E I +  + +W  K+GD V   DNI ++++DK  + ++S  DGI+  + 
Sbjct: 2   KKINILVPDLPESISDATVVKWHKKIGDTVHCDDNIVDIETDKVMLEVSSPCDGILQSIL 61

Query: 563 HDIDQTALVGQPLVDID 613
               +  +  Q L +I+
Sbjct: 62  EKEGKVVISQQTLGEIN 78


>UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to
           ENSANGP00000010144; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000010144 - Nasonia
           vitripennis
          Length = 483

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 38/164 (23%), Positives = 72/164 (43%)
 Frame = +2

Query: 185 RVLSSFIAMSILVRRSVFQLRTVNRCRKIKVTTQSARNGSQLSYKTPLNESLSKELRHFH 364
           R L     +   V R+++Q    +  R  +V  +  +N      K  + +S S + R+  
Sbjct: 14  RALRRLTLLQSKVVRTLYQGGPTSCVRAQRVLDRHVQNSQT---KPHVIQSWSIQSRYIQ 70

Query: 365 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 544
           ++ ++ ++    +    + I E  ++ W  K GD V++ D +CE+++DK +V + S   G
Sbjct: 71  STSSLWEMKDVVVPAFADSISEGDVR-WEKKEGDQVKEDDVLCEIETDKTSVPVPSPAAG 129

Query: 545 IITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
           ++  +      T   G  L  IDV      G     A + P AE
Sbjct: 130 VLKNILKKDGDTVTPGTKLCQIDV--GATGGAAPSKAAETPKAE 171


>UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep:
           MGC86218 protein - Xenopus laevis (African clawed frog)
          Length = 478

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 22/72 (30%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
 Frame = +2

Query: 350 LRHFHTSHAVNKIVAFKLS--DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVT 523
           LR  HT+  +  +   ++S   +   + E  I +W  K G++V   D +CE+++DKA VT
Sbjct: 29  LRALHTAGTLRGVPGVQVSMPALSPTMEEGNIVKWLKKEGESVSAGDALCEIETDKAVVT 88

Query: 524 ITSRYDGIITRL 559
           + S  DG++ ++
Sbjct: 89  MESNDDGVLAKI 100


>UniRef50_A1UBW5 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=11; Mycobacterium|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Mycobacterium sp. (strain KMS)
          Length = 399

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 23/72 (31%), Positives = 37/72 (51%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F++  +G  + E  + +W VK GD V +   +  V++ KAAV +    +G + RL     
Sbjct: 4   FRMPALGSDMDEGTLDQWLVKPGDTVTRGQVVAVVETTKAAVEVECWQEGTVDRLLVPEG 63

Query: 575 QTALVGQPLVDI 610
           QT  VG PL  +
Sbjct: 64  QTVRVGTPLATL 75


>UniRef50_Q6CF67 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome B of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 410

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R  HT+  + +   F +  +   + E  I  W VK GD     D I E+++DKA + + +
Sbjct: 12  RLLHTTPRLYQASNFAMPAMSPTMTEGGIVSWKVKEGDEFSAGDVILEIETDKAQIDVEA 71

Query: 533 RYDGIITRLY-----HDI---DQTALVGQPLVDIDVQD----SENDGKP 643
             DG++ ++Y      DI   D  A++ +P  DI   D     E+DGKP
Sbjct: 72  ADDGVMAKIYKKDGDKDIQVGDTIAVIAEPGDDIKTIDIPAPVESDGKP 120


>UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex; n=62; Proteobacteria|Rep:
           Dihydrolipoyllysine-residue acetyltransferase component
           of pyruvate dehydrogenase complex - Escherichia coli
           (strain K12)
          Length = 630

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 28/95 (29%), Positives = 42/95 (44%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           +  K+ DIG    EV I E  VKVGD V+   ++  V+ DKA++ + S   GI+  +   
Sbjct: 3   IEIKVPDIGAD--EVEITEILVKVGDKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVS 60

Query: 569 IDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
           +      G  ++  D  D   D  P      K  A
Sbjct: 61  VGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAA 95



 Score = 37.9 bits (84), Expect = 0.22
 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
 Frame = +2

Query: 428 EVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVD 607
           EV + E  VKVGD V    ++  V+ DKA++ + + + G++  L  ++      G  ++ 
Sbjct: 218 EVEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMI 277

Query: 608 IDVQDSENDGKPT--DVAPDKPVAE 676
            +V+ +     P   + A   P A+
Sbjct: 278 FEVEGAAPAAAPAKQEAAAPAPAAK 302



 Score = 36.7 bits (81), Expect = 0.51
 Identities = 20/85 (23%), Positives = 37/85 (43%)
 Frame = +2

Query: 419 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 598
           G  EV + E  VKVGD V+   ++  V+ DKA++ + + + G +  +  ++      G  
Sbjct: 114 GSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEIKVNVGDKVSTGSL 173

Query: 599 LVDIDVQDSENDGKPTDVAPDKPVA 673
           ++  +V        P       P A
Sbjct: 174 IMVFEVAGEAGAAAPAAKQEAAPAA 198


>UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex; n=15; Proteobacteria|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex -
           Buchnera aphidicola subsp. Baizongia pistaciae
          Length = 410

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I+   + D+ E + +  I +W  K GD VQ+   + ++++DK  + I S  DGI+  +  
Sbjct: 3   IINIFIPDLPESVTDATIIKWHKKKGDKVQEDTILVDIETDKVILEIPSPSDGILNSIIA 62

Query: 566 DIDQTALVGQ---PLVDIDVQDSENDGKPTD 649
           D  +  L GQ    L+ I +++ E   K T+
Sbjct: 63  DKGKIVLPGQVIGTLLKIGIKNEEKIIKTTN 93


>UniRef50_Q8D6Q5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
           complex, dihydrolipoamide acyltransferase component;
           n=13; Vibrionaceae|Rep: Pyruvate/2-oxoglutarate
           dehydrogenase complex, dihydrolipoamide acyltransferase
           component - Vibrio vulnificus
          Length = 381

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F L D+GEG+ E  I +W V VGD V+    I  V++ KA V + + + G I   + +  
Sbjct: 4   FILPDLGEGLAESEIIKWHVSVGDKVEVDQVILTVETAKATVDVPAPWAGTIITRHGNEG 63

Query: 575 QTALVGQPLVDIDVQD-SENDGKPTDVAPD 661
               +G  L++I+  D +EN  +      D
Sbjct: 64  DVVNIGALLLEIEDGDVTENSDQKVQQRED 93


>UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1;
           Streptomyces coelicolor|Rep: Putative acyltransferase -
           Streptomyces coelicolor
          Length = 417

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/90 (28%), Positives = 40/90 (44%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           V+  L  +GE + E  +  W  +VGD V+  + + EV +DK    I S   G++  +   
Sbjct: 3   VSVTLPALGESVTEGTVTRWLKQVGDRVEADEPLLEVSTDKVDTEIPSPAAGVLLEILAA 62

Query: 569 IDQTALVGQPLVDIDVQDSENDGKPTDVAP 658
            D+T  VG  L  I   D+         AP
Sbjct: 63  EDETVEVGAGLGIIGAPDTAPAAPAAPAAP 92


>UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
           sp. NRRL B-14911|Rep: Pyruvate dehydrogenase E2 -
           Bacillus sp. NRRL B-14911
          Length = 391

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 27/76 (35%), Positives = 41/76 (53%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           KL DIGEG+ E  I  + VK GD V+  + + EVQ+DK    I +   GI+        +
Sbjct: 4   KLHDIGEGMSEAEINCFLVKQGDFVRADEPLVEVQTDKMTAEIPAPRAGIVREFAVKPGE 63

Query: 578 TALVGQPLVDIDVQDS 625
           T  VG  L+ ++ ++S
Sbjct: 64  TVEVGAVLLLLEPENS 79


>UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1;
           marine actinobacterium PHSC20C1|Rep: Dihydrolipoamide
           acetyltransferase - marine actinobacterium PHSC20C1
          Length = 425

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
 Frame = +2

Query: 422 IREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPL 601
           + E  +  W   VGD V+  + ICEV +DK  + + S +DG + R+    D    VG  +
Sbjct: 15  MEEGTMVAWLKNVGDPVRSGEPICEVATDKVDMEVESPFDGTLARIIAQPDDVYAVGDTI 74

Query: 602 VDIDVQDSENDG----KPTDVAP 658
             I     +  G    +PTD AP
Sbjct: 75  AFITTDADDLLGGLFDEPTDEAP 97


>UniRef50_A0LLM2 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=1; Syntrophobacter
           fumaroxidans MPOB|Rep: Catalytic domain of components of
           various dehydrogenase complexes - Syntrophobacter
           fumaroxidans (strain DSM 10017 / MPOB)
          Length = 443

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 23/77 (29%), Positives = 38/77 (49%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           V F+L D+GEGI E  I E  V VGD V     +  +++DKA   + +   G++  +   
Sbjct: 3   VEFRLPDLGEGIHEGEIVEVLVSVGDRVLDGQPVMVIETDKATTEVPAPVSGVVKEIRVK 62

Query: 569 IDQTALVGQPLVDIDVQ 619
             +   VG  L+  + +
Sbjct: 63  PGEVVKVGAVLMTFEAE 79


>UniRef50_A0JS87 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=1; Arthrobacter sp. FB24|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Arthrobacter sp. (strain FB24)
          Length = 477

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 21/80 (26%), Positives = 38/80 (47%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           +  +G  +    + EW +K GD V + D +  V +DK  + + S  +G++  L  D+  T
Sbjct: 1   MPSLGADMEHGKMVEWLIKPGDYVHRGDVVAVVDTDKTVMDVESFEEGVVAELLVDVGTT 60

Query: 581 ALVGQPLVDIDVQDSENDGK 640
             +G PL  I     +  G+
Sbjct: 61  VPIGTPLARITRTPDDGAGQ 80


>UniRef50_Q830B2 Cluster: Acetyl-CoA carboxylase, biotin carboxyl
           carrier protein; n=2; Enterococcus|Rep: Acetyl-CoA
           carboxylase, biotin carboxyl carrier protein -
           Enterococcus faecalis (Streptococcus faecalis)
          Length = 162

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/54 (42%), Positives = 32/54 (59%)
 Frame = +2

Query: 440 KEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPL 601
           KE FVKVGD V+  D +C V++ K    IT+  DG+IT +  + +     GQPL
Sbjct: 102 KENFVKVGDTVKTGDVVCIVEAMKLMNEITATVDGVITEILVNNEDVVEFGQPL 155


>UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7;
           root|Rep: Dihydrolipoamide dehydrogenase - Mycoplasma
           capricolum
          Length = 629

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/85 (32%), Positives = 42/85 (49%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K +DIGEG+ E  + E  VKVGD V++   +  V++DK    I S   G I  +     Q
Sbjct: 5   KFADIGEGLTEGTVAEVLVKVGDVVKEGQPLYFVETDKVNSEIPSPVAGKIAIINISTGQ 64

Query: 578 TALVGQPLVDIDVQDSENDGKPTDV 652
              VG  +++ID   S +    + V
Sbjct: 65  EIKVGDVVIEIDDGSSTSTASTSKV 89


>UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2
           component; n=3; Bacteria|Rep: Pyruvate dehydrogenase
           complex E2 component - Vesicomyosocius okutanii subsp.
           Calyptogena okutanii (strain HA)
          Length = 507

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 27/76 (35%), Positives = 42/76 (55%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           L DIG+   EV I E  V VGD +   D+I  ++ DK+++ I S Y GIIT++  +I   
Sbjct: 9   LPDIGD-FYEVKIIEILVNVGDKINTNDSIVTLEKDKSSMKIPSPYTGIITKIEVNIGNK 67

Query: 581 ALVGQPLVDIDVQDSE 628
                 ++ I+ + SE
Sbjct: 68  IKQNDIILSIESEYSE 83



 Score = 33.1 bits (72), Expect = 6.3
 Identities = 23/115 (20%), Positives = 56/115 (48%)
 Frame = +2

Query: 266 KIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKE 445
           ++ +  +  +N   LS ++  +E +    ++    +   +I+   + +IG+   E+ + E
Sbjct: 61  EVNIGNKIKQNDIILSIESEYSE-IQNTNKNIKNEYQKTEIIPVVVPNIGD-FDEIEVIE 118

Query: 446 WFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDI 610
             V VGD +   D+I  ++SDKA++ I +   G +  +   +     +G  +++I
Sbjct: 119 ILVSVGDELSVEDSIITLESDKASMEIPTPVAGKVININVALGDKISLGTLILNI 173


>UniRef50_Q4AFR6 Cluster: Biotin/lipoyl attachment; n=1; Chlorobium
           phaeobacteroides BS1|Rep: Biotin/lipoyl attachment -
           Chlorobium phaeobacteroides BS1
          Length = 214

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 27/76 (35%), Positives = 38/76 (50%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           IV  K+   GE I EV I  W V  G  V   ++I E+ SDKA +++ +  +G IT L  
Sbjct: 2   IVEIKVPTPGESITEVQIASWLVANGQQVTSDEDIVEIDSDKATLSVAAGAEGKITILAE 61

Query: 566 DIDQTALVGQPLVDID 613
           +   T  V   +  ID
Sbjct: 62  E-GATVEVNSIIATID 76


>UniRef50_Q4AFC2 Cluster: Biotin/lipoyl attachment; n=1; Chlorobium
           phaeobacteroides BS1|Rep: Biotin/lipoyl attachment -
           Chlorobium phaeobacteroides BS1
          Length = 119

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +GE I E  I  W   VG+ V++ D++ E+ +DK    I S  +G++++L         V
Sbjct: 11  LGESIIEATITRWVKNVGEAVEEDDSLVEIATDKVDSEIPSPVEGVLSKLLFKEGDVVPV 70

Query: 590 GQPLVDIDVQDSENDGKPTDV-APDKPVAE 676
           G  +  I+++   ++    D  A  K V E
Sbjct: 71  GTVIALIEMEGEGSEETTVDTPAAXKTVIE 100


>UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
           dihydrolipoamide succinyltransferase; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: 2-oxoglutarate
           dehydrogenase, E2 subunit, dihydrolipoamide
           succinyltransferase - Syntrophobacter fumaroxidans
           (strain DSM 10017 / MPOB)
          Length = 444

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/80 (23%), Positives = 47/80 (58%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           +  K+ ++GE ++E ++ +W+ + GD V++ + +  +++DK  + +++  DG++  L  +
Sbjct: 3   IEVKVPEVGESVQEALLVQWYRRDGDMVRKGEILFIIETDKVTLEVSADADGLLKILVPE 62

Query: 569 IDQTALVGQPLVDIDVQDSE 628
             QT  +G  +  ID +  E
Sbjct: 63  -GQTVRIGTVVATIDSEARE 81


>UniRef50_Q4QCG0 Cluster: Dihydrolipoamide acetyltransferaselike
           protein; n=2; Leishmania|Rep: Dihydrolipoamide
           acetyltransferaselike protein - Leishmania major
          Length = 394

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 23/79 (29%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD-GIITRLYHDIDQTALVGQPLVDID 613
           + EW  K+G+ V++ D  C +Q+DKA V  T+ ++ G + ++Y    Q+A V + +  + 
Sbjct: 29  VVEWKKKIGELVKESDVFCTIQTDKAVVDYTNTFESGYLAKIYCGNGQSAPVAKTIA-VM 87

Query: 614 VQDSENDGKPTDVAPDKPV 670
           V D+ +  K  +  P+  V
Sbjct: 88  VSDAADVSKADEYTPEGEV 106



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 23/79 (29%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD-GIITRLYHDIDQTALVGQPLVDID 613
           + EW  K+G+ V++ D  C +Q+DKA V  T+ ++ G + ++Y    Q+A V + +  + 
Sbjct: 155 VVEWKKKIGELVKESDVFCTIQTDKAVVDYTNTFESGYLAKIYCGNGQSAPVAKTIA-VM 213

Query: 614 VQDSENDGKPTDVAPDKPV 670
           V D+ +  K  +  P+  V
Sbjct: 214 VSDAADVEKVANYYPEDAV 232


>UniRef50_Q7RWS2 Cluster: Putative uncharacterized protein
           NCU00050.1; n=2; Sordariomycetes|Rep: Putative
           uncharacterized protein NCU00050.1 - Neurospora crassa
          Length = 413

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 3/114 (2%)
 Frame = +2

Query: 344 KELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVT 523
           + +R F TS A      F +  +   + E  I  W VK GD     D + E+++DKA + 
Sbjct: 4   RSVRGFRTSAAALAAQNFTMPALSPTMTEGNIATWRVKEGDKFSAGDVLLEIETDKATMD 63

Query: 524 ITSRYDGIITRLY-HDIDQTALVGQPLVDI--DVQDSENDGKPTDVAPDKPVAE 676
           + ++ DG++ ++  +D  +   VG  +  I  +  D  +   P D AP    AE
Sbjct: 64  VEAQDDGVMVKIMKNDGAKGVAVGARIAVIAEEGDDISSLEIPADAAPQSKPAE 117


>UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase
           component of pyruvate dehydrogenase complex; n=2;
           Psychrobacter|Rep: Dihydrolipoyllysine acetyltransferase
           component of pyruvate dehydrogenase complex -
           Psychrobacter arcticum
          Length = 578

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 22/80 (27%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
 Frame = +2

Query: 419 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 598
           G+    + E  V VGD + + DNI  ++SDKA+V + S   G +T++   +      G  
Sbjct: 9   GVDSAEVSEIMVAVGDVIAKDDNIILLESDKASVEVPSSAAGKVTKISVAVGDQVSEGMV 68

Query: 599 LVDIDVQ-DSENDGKPTDVA 655
           L++++ + ++++D + T+ A
Sbjct: 69  LIELESETENQDDSQSTEAA 88



 Score = 37.1 bits (82), Expect = 0.39
 Identities = 21/71 (29%), Positives = 34/71 (47%)
 Frame = +2

Query: 419 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 598
           G+ E  + E  V VGD V    +I  ++SDKA+V + +   G + ++          GQ 
Sbjct: 138 GVDEAQVSEIMVSVGDMVTADQSILLIESDKASVEVPAPQAGKVEKILVQTGDMVANGQD 197

Query: 599 LVDIDVQDSEN 631
            + I  Q S+N
Sbjct: 198 FIVIIGQSSDN 208


>UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2
           component/dihydrolipoamide succinyltransferase; n=2;
           Desulfuromonadales|Rep: 2-oxoglutarate dehydrogenase, E2
           component/dihydrolipoamide succinyltransferase -
           Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
          Length = 396

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 17/52 (32%), Positives = 33/52 (63%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIIT 553
           ++ +IGE I E  + +W  + G  VQ+ D +CE+++DK  + + +  DG++T
Sbjct: 4   RIPEIGESIIEAKLAKWHCQDGAQVQKDDLLCELETDKITLELFAETDGVVT 55


>UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex
           dihydrolipoamide acetyltransferase; n=7; Bacteria|Rep:
           Pyruvate dehydrogenase complex dihydrolipoamide
           acetyltransferase - Microscilla marina ATCC 23134
          Length = 547

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 23/71 (32%), Positives = 39/71 (54%)
 Frame = +2

Query: 365 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 544
           T   V+      +  + + + E VI  W  KVGDN+Q+ D I EV++DKA + + +  +G
Sbjct: 115 TEVTVDNATVVTMPKMSDTMEEGVIVSWLKKVGDNIQEGDIIAEVETDKATMELEAYDEG 174

Query: 545 IITRLYHDIDQ 577
             T LY  +++
Sbjct: 175 --TLLYVAVEE 183



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 26/64 (40%), Positives = 38/64 (59%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+SD  E   E VI +W  KVGD +Q+ D I EV++DKA + + S  +G  T LY  ++ 
Sbjct: 9   KMSDTME---EGVIAKWLKKVGDTIQEGDIIAEVETDKATMELESYDEG--TLLYVAVED 63

Query: 578 TALV 589
             +V
Sbjct: 64  GGVV 67


>UniRef50_Q9SXV7 Cluster: Dihydrolipoamide acetyltransferase; n=1;
           Lithospermum erythrorhizon|Rep: Dihydrolipoamide
           acetyltransferase - Lithospermum erythrorhizon
          Length = 189

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 27/103 (26%), Positives = 53/103 (51%), Gaps = 3/103 (2%)
 Frame = +2

Query: 350 LRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 529
           +RHF ++     +++  +  +   + +  I +W  K GD +   D +CE+++DKA +   
Sbjct: 63  VRHFSSADPPQTVLS--MPALSPTMSQGNIAKWLKKEGDKIAAGDVLCEIETDKATLEYE 120

Query: 530 SRYDGIITR-LYHDIDQTALVGQPL-VDIDVQDS-ENDGKPTD 649
           S  DG + + L  D  +   VG+P+ + ++ QD  +N   P D
Sbjct: 121 SVEDGFLAKILVPDGSKDVPVGKPIAITVEEQDDLKNVSVPVD 163


>UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex, mitochondrial; n=8; Dikarya|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex,
           mitochondrial - Coccidioides immitis
          Length = 484

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 23/84 (27%), Positives = 43/84 (51%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  + E I +  +K++  ++GD V++ + +  +++DK  VT+ +   GII       + 
Sbjct: 97  KVPQMAESISDGTLKQFSKQIGDFVERDEELATIETDKIDVTVNAPESGIIKEFLAKEED 156

Query: 578 TALVGQPLVDIDVQDSENDGKPTD 649
           T  VGQ LV +    +EN     D
Sbjct: 157 TVTVGQDLVKLQ-PSTENPSSGKD 179


>UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex, mitochondrial precursor; n=21;
           Ascomycota|Rep: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex, mitochondrial precursor -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 463

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 19/85 (22%), Positives = 45/85 (52%)
 Frame = +2

Query: 383 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 562
           K  + ++  + E + E  +KE+   VGD +++ + +  +++DK  + + S   G +T+L 
Sbjct: 72  KSTSIEVPPMAESLTEGSLKEYTKNVGDFIKEDELLATIETDKIDIEVNSPVSGTVTKLN 131

Query: 563 HDIDQTALVGQPLVDIDVQDSENDG 637
              + T  VG+ L  ++  ++  +G
Sbjct: 132 FKPEDTVTVGEELAQVEPGEAPAEG 156


>UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase;
           n=8; Bacteria|Rep: Dihydrolipoamide succinyl transferase
           - Rhizobium loti (Mesorhizobium loti)
          Length = 424

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 24/86 (27%), Positives = 41/86 (47%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           ++  +GE + E  I +WF KVGD +   + + E+++DK  V + +   G +  +     +
Sbjct: 6   RVPTLGESVTEATIGKWFKKVGDAIAVDEPLVELETDKVTVEVPAAAAGTLGEIVAKEGE 65

Query: 578 TALVGQPLVDIDVQDSENDGKPTDVA 655
           T  VG  L  I    S    KP  V+
Sbjct: 66  TVGVGALLGSISAGGSAPATKPQAVS 91


>UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;
           n=2; Acidobacteria|Rep: Dihydrolipoamide
           S-succinyltransferase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 555

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 2/90 (2%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           +  +GE I E  I +W  + GD VQ+ + + E+ +DK    I +   GI+  +     QT
Sbjct: 7   MPQMGESIFEGTITKWLKQPGDQVQRDEPLFEISTDKVDAEIPAPAAGILKEIKAQAGQT 66

Query: 581 ALVGQPLVDIDVQDSENDG--KPTDVAPDK 664
             V   +  ID   S      KP   AP K
Sbjct: 67  VQVNTVVAIIDAAGSATTSAPKPAAAAPPK 96



 Score = 38.3 bits (85), Expect = 0.17
 Identities = 22/86 (25%), Positives = 37/86 (43%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           +  +GE I E  I +W   VGD VQ+ + + E+ +DK    I +   G+++ +      T
Sbjct: 127 MPQMGESIFEGTITKWLKNVGDTVQRDEPLFEISTDKVDAEIPAPVAGVLSEIKVQAGAT 186

Query: 581 ALVGQPLVDIDVQDSENDGKPTDVAP 658
             V   +  I      +   P   AP
Sbjct: 187 VQVNTVVATIGGAAGASARAPQAAAP 212


>UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;
           n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
           Dihydrolipoamide S-succinyltransferase - Herpetosiphon
           aurantiacus ATCC 23779
          Length = 442

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 21/86 (24%), Positives = 44/86 (51%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           ++  +G  + E  + +W  K GD V + + I EV++DK  + I +   G I +   +  +
Sbjct: 6   EMPKMGYDMVEGTLAKWLKKPGDEVSRGEPIAEVETDKVTIEIEAFEAGTILKFLVNEGE 65

Query: 578 TALVGQPLVDIDVQDSENDGKPTDVA 655
           T  VG P+ +ID    +++ +  + +
Sbjct: 66  TVPVGAPIAEIDDGSGDDEAEAANAS 91


>UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2
           component, dihydrolipoamide succinyltransferase; n=1;
           Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
           dehydrogenase, E2 component, dihydrolipoamide
           succinyltransferase - Orientia tsutsugamushi (strain
           Boryong) (Rickettsia tsutsugamushi)
          Length = 425

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
 Frame = +2

Query: 380 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           NK     L  +GE +    I +W  K GD V   + I EV+SDK  + I +   G IT++
Sbjct: 5   NKETNIVLPSLGESVSTGTISKWHKKEGDIVALDEKIVEVESDKVGIDINANVPGKITKI 64

Query: 560 YHDIDQTALVGQPLVDI--DVQDSE-NDGKPTDVAPDKPVAE 676
             +      VG+ +  I  DV   E +  K +++  +  + E
Sbjct: 65  LKNEGDNVEVGEVICVIRSDVLQKEIHSSKSSEIDINLSICE 106


>UniRef50_A1SJ23 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=18; Actinomycetales|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 597

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           L  +GE + E  +  W  +VGD+V   + + EV +DK    I S   G +  +  + D T
Sbjct: 7   LPALGESVTEGTVTRWLKQVGDSVAVDEPLLEVSTDKVDTEIPSPIAGTLLEIRANEDDT 66

Query: 581 ALVGQPLVDI-DVQDSEND--GKPTDVAPD 661
             VG  L  I D  +S  D  G   +  PD
Sbjct: 67  VEVGAVLAVIGDAGESSGDSGGAQAEAQPD 96



 Score = 41.5 bits (93), Expect = 0.018
 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 3/98 (3%)
 Frame = +2

Query: 392 AFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDI 571
           A  L  +GE + E  +  W   VGD V   + + EV +DK    I S   G +  +    
Sbjct: 141 AVTLPALGESVTEGTVTRWLKSVGDEVAVDEPLLEVSTDKVDTEIPSPVAGTLLEIKVAE 200

Query: 572 DQTALVGQPLVDI---DVQDSENDGKPTDVAPDKPVAE 676
           D+T  VG  L  I       +E+  +PT     +P  E
Sbjct: 201 DETVEVGAELAVIGSGQAAPAESKPEPTPEPEPEPTPE 238


>UniRef50_A0LSF1 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=1; Acidothermus
           cellulolyticus 11B|Rep: Catalytic domain of components
           of various dehydrogenase complexes - Acidothermus
           cellulolyticus (strain ATCC 43068 / 11B)
          Length = 449

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 24/92 (26%), Positives = 49/92 (53%), Gaps = 3/92 (3%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           + + ++E  I +W  KVGD V++ D + E+++DKA + + +   G++ ++  +  +   +
Sbjct: 9   LSDTMQEGTITQWTKKVGDQVEKGDVLAEIETDKAVMELEAYDSGVLEKILVEPGKPVPI 68

Query: 590 GQPLVDIDVQD--SENDGKPT-DVAPDKPVAE 676
           G P+  I   +   E  G  T   AP +P A+
Sbjct: 69  GTPIAIIGSGEGLQEPTGDSTAHAAPAEPKAD 100


>UniRef50_A0G738 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=4; Burkholderiaceae|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Burkholderia phymatum STM815
          Length = 382

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/72 (31%), Positives = 37/72 (51%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           ++ F L  +G  + E  + EW +K GD V +   +  V + KAAV I S Y+G +  L  
Sbjct: 1   MIEFTLPSMGADMDEGTLLEWKIKPGDAVTKGQIVAIVDTSKAAVDIESWYEGTVYELIT 60

Query: 566 DIDQTALVGQPL 601
           +  +   VG P+
Sbjct: 61  EPGEKIPVGTPM 72


>UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;
           Euplotes sp. BB-2004|Rep: Pyruvate dehydrogenase E2
           subunit - Euplotes sp. BB-2004
          Length = 459

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/75 (30%), Positives = 38/75 (50%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 616
           + +W  KVGD V+  D + EV++DKA V    + DG + +L  +     +    LV I V
Sbjct: 57  LAKWCKKVGDQVEPGDILAEVETDKATVDFEMQEDGYVAKLLVEEGAQDIALGELVAISV 116

Query: 617 QDSENDGKPTDVAPD 661
           +D ++     D  P+
Sbjct: 117 EDEDDVAAFKDYKPE 131


>UniRef50_A5ZAG1 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 148

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 19/55 (34%), Positives = 35/55 (63%)
 Frame = +2

Query: 449 FVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDID 613
           FV+VGD V++   +  V++ K    I S +DG++T++  + +QT   GQPL +++
Sbjct: 94  FVQVGDTVKKGQVVAIVEAMKLMNEIESEFDGVVTKVLVENEQTVEYGQPLFEVE 148


>UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransferase
           (Catalytic domain) protein; n=2; Bacteroidetes|Rep:
           2-oxo acid dehydrogenases acyltransferase (Catalytic
           domain) protein - Algoriphagus sp. PR1
          Length = 432

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 19/78 (24%), Positives = 39/78 (50%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           V   +  +GE I E  I  W  K G+ ++Q +++ EV +DK    + + + G++ ++   
Sbjct: 4   VEMLMPKMGESIIEGTILGWLKKEGETIEQDESVLEVATDKVDTEVPATHPGVLKKILAK 63

Query: 569 IDQTALVGQPLVDIDVQD 622
                 VG P+  I+ ++
Sbjct: 64  EGDVVAVGAPIAIIETEN 81


>UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;
           n=1; Chloroflexus aggregans DSM 9485|Rep:
           Dihydrolipoamide S-succinyltransferase - Chloroflexus
           aggregans DSM 9485
          Length = 435

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 19/67 (28%), Positives = 36/67 (53%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           + + + E  +  W  KVGD +   D I E+++DKA + + +   G++ ++     QT  +
Sbjct: 9   LSDTMSEGTVGRWLKKVGDQIAVGDIIAEIETDKATMELEAFESGVLQQILVPEGQTVPI 68

Query: 590 GQPLVDI 610
           GQP+  I
Sbjct: 69  GQPIAII 75


>UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component 2 of pyruvate dehydrogenase
           complex, mitochondrial precursor; n=14; cellular
           organisms|Rep: Dihydrolipoyllysine-residue
           acetyltransferase component 2 of pyruvate dehydrogenase
           complex, mitochondrial precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 539

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 29/131 (22%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
 Frame = +2

Query: 275 VTTQSARNGSQLSYKTPLNESLSKELRH---FHTSHAVNKIVAFKLSDIGEGIREVVIKE 445
           ++T S +  S ++      E +S ++R    F +S  +       +  +   + E  I  
Sbjct: 71  ISTTSTKLSSPMAGPKLFKEFISSQMRSVRGFSSSSDLPPHQEIGMPSLSPTMTEGNIAR 130

Query: 446 WFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDS 625
           W  K GD V   + +CEV++DKA V +    +G + ++  +     +    ++ I V+D 
Sbjct: 131 WLKKEGDKVAPGEVLCEVETDKATVEMECMEEGFLAKIVKEEGAKEIQVGEVIAITVEDE 190

Query: 626 ENDGKPTDVAP 658
           ++  K  D  P
Sbjct: 191 DDIQKFKDYTP 201


>UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate
           dehydrogenase complex, component X; n=4;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           pyruvate dehydrogenase complex, component X -
           Strongylocentrotus purpuratus
          Length = 482

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 5/82 (6%)
 Frame = +2

Query: 428 EVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY-----HDIDQTALVG 592
           E  I  W    GD +   D ICE+++DKA V + +  DGI+ ++       +I  TAL+G
Sbjct: 68  EGTIVSWLKAEGDPIAAGDGICEIETDKATVIMDADDDGIMAKILVPEGSKNIPITALIG 127

Query: 593 QPLVDIDVQDSENDGKPTDVAP 658
             L+  + +D ++   PT  AP
Sbjct: 128 --LMVPEGEDYKDVDMPTQAAP 147


>UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).;
           n=3; Amniota|Rep: Apoptosis inhibitor 5 (API-5). -
           Gallus gallus
          Length = 458

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDID 613
           I +W  K G+ V   D +CE+++DKA VT+ S  DGI+ + L  +  +   +G  L+ + 
Sbjct: 67  IVKWLKKEGEMVNAGDALCEIETDKAVVTMESSDDGILAKILVEEGSKNVRLGS-LIGLL 125

Query: 614 VQDSENDGKPTDVAPD 661
           V++ + D K  ++  D
Sbjct: 126 VEEGQ-DWKQVEIPAD 140


>UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome
           shotgun sequence; n=5; Bilateria|Rep: Chromosome 10
           SCAF15019, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 461

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 31/115 (26%), Positives = 58/115 (50%), Gaps = 4/115 (3%)
 Frame = +2

Query: 227 RSVFQLRTVNRC---RKIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAV-NKIVA 394
           RS+  LR  N+    R +   T +       + K+ L  ++ + +++F TS A  +++V 
Sbjct: 14  RSLSALRQGNQALARRSLSALTINTSISVNNNVKSNLRTNVFR-IQYFRTSVAYRDEVVT 72

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
            K     E + E  ++ W   VGD V + + +CE+++DK +V + S   G+I  L
Sbjct: 73  VKTPAFAESVTEGDVR-WEKAVGDTVTEDEVVCEIETDKTSVQVPSPAAGVIEEL 126


>UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1;
           Bacillus clausii KSM-K16|Rep: Acetoin dehydrogenase E2
           component - Bacillus clausii (strain KSM-K16)
          Length = 410

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 22/73 (30%), Positives = 37/73 (50%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +G  + E  I  W  +VG+ V + + I E+ S+K    + ++ DGI+   Y D+D    V
Sbjct: 9   LGMTMSEGTIVNWCKEVGEPVTKGEAIVEISSEKLTQELEAQEDGILLAKYGDVDAVMKV 68

Query: 590 GQPLVDIDVQDSE 628
           G+ L  I  +  E
Sbjct: 69  GEVLAHIGQEGEE 81


>UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3;
           Pelobacter|Rep: Dihydrolipoamide acetyltransferase -
           Pelobacter carbinolicus
          Length = 450

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
 Frame = +2

Query: 380 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           N+I+A  +   G  + E  I  W +  GD ++    I EV++DK A  + S  +GI+ R 
Sbjct: 4   NRIIALTMPKWGLTMEEGTISSWLMDEGDTIEVGSEILEVETDKIAQPVESAVEGILRRK 63

Query: 560 YHDIDQ----TALVGQPLVDIDVQDSEND 634
             + D+     AL+G    + DV + E D
Sbjct: 64  IGEEDEEYPVKALIGIIAAE-DVTEEEID 91



 Score = 38.7 bits (86), Expect = 0.13
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
 Frame = +2

Query: 365 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 544
           T+ A   I    +   G  + E  I  W +  GD V+    I EV++DK A  + S   G
Sbjct: 114 TAAAPEGIYELTMPKWGLTMEEGTISSWLIDEGDEVEVGTEIMEVETDKIAQPVESTVAG 173

Query: 545 IITRLYHDIDQ----TALVGQPLVDIDVQDSEND 634
           ++ R   + D+     AL+G  + D  V D++ D
Sbjct: 174 VLRRKIGEEDEEYPVKALIG-IIADASVSDADID 206


>UniRef50_A6Q3I4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
           complex, E2 component, dihydrolipoamide
           acetyltransferase; n=1; Nitratiruptor sp. SB155-2|Rep:
           Pyruvate/2-oxoglutarate dehydrogenase complex, E2
           component, dihydrolipoamide acetyltransferase -
           Nitratiruptor sp. (strain SB155-2)
          Length = 408

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 29/82 (35%), Positives = 44/82 (53%)
 Frame = +2

Query: 383 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 562
           KIV   LSD  +  +  +IK W VK GD V + D I EV+SDKA + + +  DG++ +L 
Sbjct: 4   KIVMPVLSDTMD--KGKLIK-WHVKEGDVVHKGDVIAEVESDKAIMEVQTFKDGVVKKLL 60

Query: 563 HDIDQTALVGQPLVDIDVQDSE 628
                   V +P+  +D +  E
Sbjct: 61  VKEGDEVPVKEPIAILDTEVKE 82


>UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex; n=2; Bacteroidetes|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex -
           Microscilla marina ATCC 23134
          Length = 454

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 23/96 (23%), Positives = 43/96 (44%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           +V   +  +GE + E  I +W   VGD +++ + + EV +DK    + + + G++  +  
Sbjct: 3   LVEMVMPKMGESVMEGTILQWLKAVGDEIEEDEPVLEVATDKVDTEVPATHAGVLKEVLA 62

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
                  VGQ +  I    S +   P D    +P A
Sbjct: 63  QEGDVVQVGQTIAII----STDGDAPADAPASQPEA 94


>UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2
           component, dihydrolipoamide succinyltransferase,
           putative; n=5; Trypanosomatidae|Rep: 2-oxoglutarate
           dehydrogenase, E2 component, dihydrolipoamide
           succinyltransferase, putative - Leishmania major
          Length = 389

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           ++  +  I E I    +  W  KVGD V + + IC+++SDK  V + +  +G+IT++  +
Sbjct: 26  LSINVPTIAESISTGKVVNWTKKVGDAVAEDEVICQIESDKLNVDVRAPANGVITKINFE 85

Query: 569 IDQTALVGQPLVDIDVQDSENDGKP--TDVAPDKPVAE 676
                 VG  L  +    +     P   +V  D P AE
Sbjct: 86  EGADVEVGAQLSTMKEGPAPAAAAPKAAEVKLDAPKAE 123


>UniRef50_Q6CNU8 Cluster: Kluyveromyces lactis strain NRRL Y-1140
           chromosome E of strain NRRL Y- 1140 of Kluyveromyces
           lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
           lactis strain NRRL Y-1140 chromosome E of strain NRRL Y-
           1140 of Kluyveromyces lactis - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 405

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +2

Query: 350 LRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 529
           LR  H    + K  AF +  +   +    + +W  K GD     D + EV++DKA + + 
Sbjct: 12  LRQLHQCRTMLKAQAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVE 71

Query: 530 SRYDGIITRLYHDIDQTAL-VGQPLVDI-DVQD 622
           ++ DG + ++  +     + VG+P+  I DV D
Sbjct: 72  AQDDGKLAKILKENGAKDIPVGEPIAYIADVDD 104


>UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid
           dehydrogenase E2; n=2; Bacilli|Rep: Branched-chain
           alpha-keto acid dehydrogenase E2 - Symbiobacterium
           thermophilum
          Length = 459

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 26/91 (28%), Positives = 38/91 (41%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           +  +GE + E  I  W V  GD V+++  I EV +DK    I +  DG I  L      T
Sbjct: 5   MPQLGESVTEGTINRWLVAPGDVVKRYQPIAEVITDKVNAEIPAPADGRILTLDVPEGST 64

Query: 581 ALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
             VG  +  ++V   +    P  V      A
Sbjct: 65  VPVGARIATMEVAGEDAGQAPAPVGASAQAA 95


>UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
           complex dihydrolipoamide acyltransferase (E2) component
           and related enzymes; n=1; Nitrosococcus oceani ATCC
           19707|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
           dihydrolipoamide acyltransferase (E2) component and
           related enzymes - Nitrosococcus oceani (strain ATCC
           19707 / NCIMB 11848)
          Length = 447

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 25/94 (26%), Positives = 45/94 (47%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL ++GE I    + +  V  GD +++   + E+++DKA V I S   G I  L     
Sbjct: 5   FKLPELGENIESGDVAKVLVSPGDTLEKDQPVLELETDKAVVEIPSTASGKIKELKVKAG 64

Query: 575 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
               +GQ ++ ++ +  E   +    A ++P  E
Sbjct: 65  DQVAIGQVILTLE-EGGEEAQEDVPAAREEPKPE 97


>UniRef50_Q4DYI5 Cluster: Dihydrolipoamide acetyltransferase,
           putative; n=2; Trypanosomatidae|Rep: Dihydrolipoamide
           acetyltransferase, putative - Trypanosoma cruzi
          Length = 269

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD-GIITRLYHDIDQTALVGQPLVDID 613
           I EW  KVGD V + +  C VQ+DKA V  T+ +D G + ++     +T  V + +  + 
Sbjct: 28  IVEWKKKVGDLVNENEVFCTVQTDKAVVDYTNTFDAGYLAKILCHSGETVPVAKTIA-VM 86

Query: 614 VQDSENDGKPTDVAPD 661
           V+D  +  K  D  P+
Sbjct: 87  VEDEADIPKIADYRPE 102


>UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex; n=3; Mollicutes|Rep:
           Dihydrolipoyllysine-residue acetyltransferase component
           of pyruvate dehydrogenase complex - Mycoplasma
           capricolum subsp. capricolum (strain California kid /
           ATCC27343 / NCTC 10154)
          Length = 438

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K +DIGEG+ E  + E  VKVGD V++  ++  V++DK    I +   G I  +     Q
Sbjct: 5   KFADIGEGLTEGTVAEVLVKVGDVVKEGQSLYFVETDKVNSEIPAPVAGKIAVINIKAGQ 64

Query: 578 TALVGQPLVDI-DVQDSENDGKP 643
              VG  +++I D  D+    +P
Sbjct: 65  EIKVGDVVMEIEDGSDTSATSEP 87


>UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n=3;
           Danio rerio|Rep: UPI00015A4520 UniRef100 entry - Danio
           rerio
          Length = 494

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 16/41 (39%), Positives = 27/41 (65%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           I +W  K G++V   D +CE+++DKA V + S  DG++ R+
Sbjct: 79  IVKWLKKEGEDVAAGDALCEIETDKAVVVMESNEDGVLARI 119


>UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransferase
           (Component of 2- oxoglutarate dehydrogenase complex)
           protein; n=4; Bacteria|Rep: SucB; dihydrolipoamide
           succinyltransferase (Component of 2- oxoglutarate
           dehydrogenase complex) protein - Nitrosomonas europaea
          Length = 425

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 18/91 (19%), Positives = 42/91 (46%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           ++  K+  + E + E  +  W  + G+ V++ +N+ ++++DK  + + +   GI+  +  
Sbjct: 2   LIEVKVPALSESVAEATLINWHKQPGEYVERGENLIDIETDKVVLELPAPQSGILAEIIR 61

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTDVAP 658
           +   T   G+ +  ID    E        AP
Sbjct: 62  NDGATVTSGEIIARIDTAAKETKTAAQQPAP 92


>UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase; n=2; Bacteroidetes|Rep:
           Dihydrolipoyllysine-residue acetyltransferase -
           Pedobacter sp. BAL39
          Length = 549

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 20/60 (33%), Positives = 37/60 (61%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  + + + E V+ +W  KVGD ++  D + EV++DKA + + S +DG  T LY  +++
Sbjct: 6   KMPKMSDTMTEGVMAKWHKKVGDKIKSGDVMAEVETDKATMDLESYWDG--TVLYIGVEE 63



 Score = 40.7 bits (91), Expect = 0.032
 Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           +   ++  + + + E VI EW  KVGD V+  D + +V++DKA + +    +G +  +  
Sbjct: 133 VTVVRMPLLSDTMTEGVIAEWHKKVGDQVKNDDILADVETDKATMEVMGYAEGTLLHIGV 192

Query: 566 DIDQTALVGQPLVDIDVQDSENDG-KPTDVAPDKPVAE 676
           +    A V   +  +  + ++  G      AP KP A+
Sbjct: 193 EKGAAAKVNGIIAIVGPEGTDISGILAQGDAPAKPAAD 230


>UniRef50_A1W7R7 Cluster: Dihydrolipoamide dehydrogenase; n=58;
           Bacteria|Rep: Dihydrolipoamide dehydrogenase -
           Acidovorax sp. (strain JS42)
          Length = 627

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 23/77 (29%), Positives = 42/77 (54%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I+  K+ DIG+   EV + E  V+ GD ++   ++  V+SDKA++ I S + G++  L  
Sbjct: 3   IIDIKVPDIGD-FAEVGVIEVLVQPGDTIRAEQSLVTVESDKASMEIPSSHAGVVKELKV 61

Query: 566 DIDQTALVGQPLVDIDV 616
            +      G  L+ ++V
Sbjct: 62  KLGDKVAEGSVLLTLEV 78


>UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit;
           n=15; Magnoliophyta|Rep: 2-oxoglutarate dehydrogenase E2
           subunit - Arabidopsis thaliana (Mouse-ear cress)
          Length = 464

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           +V   +  +GE I +  +  +  K GD V+  + I ++++DK  + I S   G+I     
Sbjct: 93  VVEAVVPHMGESITDGTLAAFLKKPGDRVEADEAIAQIETDKVTIDIASPASGVIQEFLV 152

Query: 566 DIDQTALVGQPLVDIDVQ-DSENDGKPTDVAPDKP 667
               T   G  +  I    D+ +   P++ AP+KP
Sbjct: 153 KEGDTVEPGNKVARISTSADAVSHVAPSEKAPEKP 187


>UniRef50_A4L2T6 Cluster: AccB; n=2; Lactobacillus reuteri|Rep: AccB
           - Lactobacillus reuteri
          Length = 150

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 20/62 (32%), Positives = 37/62 (59%)
 Frame = +2

Query: 449 FVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSE 628
           +V+ GD+V++ D +C +++ K    I S ++GIIT +    ++   V QPL  +  +D +
Sbjct: 90  YVRSGDHVKKGDVVCVIEAMKMMTEIKSPFNGIITSICVSNEELVEVEQPLFSVQ-EDKD 148

Query: 629 ND 634
           ND
Sbjct: 149 ND 150


>UniRef50_A4FIZ9 Cluster: Acetoin dehydrogenase, dihydrolipoamide
           acetyltransferase component; n=1; Saccharopolyspora
           erythraea NRRL 2338|Rep: Acetoin dehydrogenase,
           dihydrolipoamide acetyltransferase component -
           Saccharopolyspora erythraea (strain NRRL 23338)
          Length = 371

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDI-- 610
           I +W+   GD+V   D++ E+ +DK A T+ S  +G++ R+       A VG  +  +  
Sbjct: 23  ITDWWASEGDDVSDGDDLAEIDTDKIAGTLESTGEGVLRRIVVAAGSDAPVGATIAVVAP 82

Query: 611 -DVQDSEND 634
            +V DSE D
Sbjct: 83  AEVPDSEID 91


>UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2
           component, dihydrolipoamide succinyltransferase; n=4;
           Bacteria|Rep: 2-oxoglutarate dehydrogenase, E2
           component, dihydrolipoamide succinyltransferase -
           Nitrococcus mobilis Nb-231
          Length = 443

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 16/84 (19%), Positives = 43/84 (51%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           +  K+  + E + E  +  W  K GD V + +N+ ++++DK  + + +  DG++ ++  D
Sbjct: 3   IEVKVPALPESVTEATVVGWHKKPGDRVARDENLVDLETDKVVLEVPAPEDGVLGKILKD 62

Query: 569 IDQTALVGQPLVDIDVQDSENDGK 640
              T +  + L  ++  ++ +  +
Sbjct: 63  EGATVVADEVLACLEQGETNSQAE 86


>UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransferase
           (Catalytic domain) protein; n=1; Salinibacter ruber DSM
           13855|Rep: 2-oxo acid dehydrogenases acyltransferase
           (Catalytic domain) protein - Salinibacter ruber (strain
           DSM 13855)
          Length = 639

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 24/99 (24%), Positives = 45/99 (45%)
 Frame = +2

Query: 362 HTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD 541
           HT+  + + V  ++  +GE I E  +  W  + GD V+Q + + E+ +DK    + S   
Sbjct: 27  HTTEIMAQ-VDVEMPKMGESITEGTVIAWHKQPGDEVEQDEILLEIGTDKVDTEVPSPKG 85

Query: 542 GIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAP 658
           G++T    +   T  VG  +  +D   +  +    D  P
Sbjct: 86  GVLTETLVEEGDTVEVGTIIATLDTDTAAAEVDADDEPP 124



 Score = 36.7 bits (81), Expect = 0.51
 Identities = 23/86 (26%), Positives = 42/86 (48%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +GE I E  +  W+  +G+ V   + I E+ +DK    + S  +G++T    +  +T  V
Sbjct: 180 MGESITEGTVVAWYKDIGEAVAIDETILEIGTDKVDTEVPSPAEGVLTEKLVEEGETVEV 239

Query: 590 GQPLVDIDVQDSENDGKPTDVAPDKP 667
           G  +V +   ++E  G     A D+P
Sbjct: 240 G-TVVALLASEAE-AGSVEPPASDEP 263


>UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacteria
           (class)|Rep: Dehydrogenase subunit - Frankia sp. (strain
           CcI3)
          Length = 487

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 25/95 (26%), Positives = 42/95 (44%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           V+  +  +GE + E  +  W  + G+ V+  + + EV +DK    I +   G+++ +   
Sbjct: 3   VSVTMPRLGESVSEGTVTRWLKQEGERVEADEPLLEVSTDKVDTEIPAPASGVVSSIKVA 62

Query: 569 IDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVA 673
            D+T  VG  L  ID   S   G     A   P A
Sbjct: 63  EDETVEVGVELAVID-DGSAGGGTAPAQATQAPAA 96


>UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-ketoacid dehydrogenase complex;
           n=4; Bacteroidetes|Rep: Lipoamide acyltransferase
           component of branched-chain alpha-ketoacid dehydrogenase
           complex - Dokdonia donghaensis MED134
          Length = 439

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +GE I E  I  W V  G++ ++ D + E+ +DK    + +   G++ +  +D +    V
Sbjct: 19  MGESITEGTIINWLVAEGESFEEGDILVEIATDKVDNEVPATSAGVMQKHLYDANAVVAV 78

Query: 590 GQPLVDIDVQ--DSENDGKPTDVAPDKP 667
           G+P+     Q  D+E    P++    +P
Sbjct: 79  GEPIATYLAQGGDAEKAINPSEKKEAQP 106


>UniRef50_A0G901 Cluster: Biotin/lipoyl attachment; n=1;
           Burkholderia phymatum STM815|Rep: Biotin/lipoyl
           attachment - Burkholderia phymatum STM815
          Length = 130

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 22/69 (31%), Positives = 34/69 (49%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           I A  +   G  + E  + EW  KVGD V++   + EV+S K    + +   GI+ R+  
Sbjct: 4   IEAVTIPKWGMTMTEGTVLEWHAKVGDKVERGQELLEVESTKVNNVVEATVSGILRRIVI 63

Query: 566 DIDQTALVG 592
           D  + A VG
Sbjct: 64  DAGEIAPVG 72


>UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_3,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 628

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 17/41 (41%), Positives = 25/41 (60%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           + +W VK GD +   D ICE+++DKA V    + DG I +L
Sbjct: 191 LMKWLVKEGDRISPGDVICEIETDKATVGFEVQEDGYIAKL 231



 Score = 34.3 bits (75), Expect = 2.7
 Identities = 14/41 (34%), Positives = 26/41 (63%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           I+++  KVGD +   D +CEV++DKA V    + +G + ++
Sbjct: 64  IQKYLKKVGDPITAGDVLCEVETDKATVGFEMQDEGFLAQI 104


>UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex; n=135; root|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex -
           Rickettsia felis (Rickettsia azadi)
          Length = 401

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 17/68 (25%), Positives = 37/68 (54%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +GE + E  I +W+ K GD V+  + + E++++K  + + +  DG I ++         V
Sbjct: 10  LGESVTEATIAKWYKKEGDPVKTDELLLEIETEKVTLEVNAPCDGTIGKISKTDGANVAV 69

Query: 590 GQPLVDID 613
           G+ + +I+
Sbjct: 70  GEEIGEIN 77


>UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex, mitochondrial precursor; n=48;
           Fungi/Metazoa group|Rep: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex, mitochondrial precursor - Homo
           sapiens (Human)
          Length = 453

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
 Frame = +2

Query: 311 SYKTPLNESLSKELRHFHTSHAV-NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDN 487
           S K  +N S+   +R F T+    + +V  K     E + E  ++ W   VGD V + + 
Sbjct: 45  SRKVVINNSVFS-VRFFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEV 102

Query: 488 ICEVQSDKAAVTITSRYDGIITRL 559
           +CE+++DK +V + S  +G+I  L
Sbjct: 103 VCEIETDKTSVQVPSPANGVIEAL 126


>UniRef50_UPI00015552BA Cluster: PREDICTED: similar to
           dihydrolipoamide S-succinyltransferase (E2 component of
           2-oxo-glutarate complex), partial; n=1; Ornithorhynchus
           anatinus|Rep: PREDICTED: similar to dihydrolipoamide
           S-succinyltransferase (E2 component of 2-oxo-glutarate
           complex), partial - Ornithorhynchus anatinus
          Length = 306

 Score = 40.7 bits (91), Expect = 0.032
 Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +2

Query: 320 TPLNESLSKELRHFHTSHA-VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICE 496
           +P+  +    +R F T+ A  + +V  K     E + E  ++ W   VGD V + + +CE
Sbjct: 103 SPVKNASVFSVRFFRTTAARKSDVVTVKTPAFAESVTEGDVR-WEKAVGDAVAEDEVVCE 161

Query: 497 VQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSEN 631
           +++DK +V + S   G+I  L          G PL  +     EN
Sbjct: 162 IETDKTSVQVPSPSAGVIEALLVPDGGKVEGGTPLFTLRKTAGEN 206


>UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate
           dehydrogenase protein X component, mitochondrial
           precursor (Dihydrolipoamide dehydrogenase-binding
           protein of pyruvate dehydrogenase complex)
           (Lipoyl-containing pyruvate dehydrogenase complex
           component X) (E3-binding protein) (E...; n=1; Apis
           mellifera|Rep: PREDICTED: similar to Pyruvate
           dehydrogenase protein X component, mitochondrial
           precursor (Dihydrolipoamide dehydrogenase-binding
           protein of pyruvate dehydrogenase complex)
           (Lipoyl-containing pyruvate dehydrogenase complex
           component X) (E3-binding protein) (E... - Apis mellifera
          Length = 598

 Score = 40.7 bits (91), Expect = 0.032
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 616
           I +W  K G+ ++  D + E+Q+DKA +T     +GI  ++       A VG+ L+ I V
Sbjct: 180 IVKWLKKEGEKIEPGDAVAEIQTDKAVMTFEIEDEGIFAKILIPEGSQAEVGE-LIAITV 238

Query: 617 Q---DSENDGKPTDVAPDKP 667
           +   D +N   PT   P  P
Sbjct: 239 EKGMDWKNVVVPTTTKPTAP 258



 Score = 39.1 bits (87), Expect = 0.096
 Identities = 28/110 (25%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
 Frame = +2

Query: 359 FHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSR 535
           FHTS   + +  +  +  +   + +  I +W  K GD ++  D + ++Q+DKA VT+   
Sbjct: 35  FHTSWVFDVQGKSILMPSLSPTMEKGTIVKWIKKEGDKIEAGDAVADIQTDKAVVTLELE 94

Query: 536 YDGIITRL-----YHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPV 670
            + I+ ++       DI    L+    VD+D +D ++   P +V+   PV
Sbjct: 95  DESILAKIIVGEGIQDIKVGTLIAL-TVDVD-EDWKSVEMPDNVSVTPPV 142


>UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2
           component, dihydrolipoamide succinyltransferase; n=2;
           Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
           component, dihydrolipoamide succinyltransferase -
           Nitrobacter hamburgensis (strain X14 / DSM 10229)
          Length = 413

 Score = 40.7 bits (91), Expect = 0.032
 Identities = 19/71 (26%), Positives = 36/71 (50%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           ++  +GE + E  I +WF K GD V   + + E+++DK  + + +   G ++ +     +
Sbjct: 5   RVPTLGESVTEATIGKWFKKAGDAVAVDEPLVELETDKVTIEVPAPSAGTLSEIVAKDGE 64

Query: 578 TALVGQPLVDI 610
           T  VG  L  I
Sbjct: 65  TVAVGALLGQI 75


>UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 448

 Score = 40.7 bits (91), Expect = 0.032
 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 8/99 (8%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD---- 568
           +  +G  +   +I EW +  GD V     +  +++DK+ + + S  +G + +L  +    
Sbjct: 7   MPQLGNSVESCIIVEWMIAEGDTVSVDQTLASIETDKSTMEVPSTAEGTVLKLLWEEGDE 66

Query: 569 ---IDQTALVGQPLVDIDVQDSENDGKPTDV-APDKPVA 673
               D   +VG+P  DI       D  P +  AP + VA
Sbjct: 67  VPVKDPLIIVGEPGEDISGLVPGGDAAPAEADAPAEQVA 105


>UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,
           lipoamide acyltransferase; n=9; Chlamydiaceae|Rep: 2-oxo
           acid dehydrogenase, E2 component, lipoamide
           acyltransferase - Chlamydia muridarum
          Length = 410

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 25/111 (22%), Positives = 47/111 (42%)
 Frame = +2

Query: 344 KELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVT 523
           K  + F +S     +  F+   IGE     ++  W  +VGD++Q+ + + EV +DK A  
Sbjct: 9   KNTKTFTSSEIRGFMFEFRFPKIGETASGGIVVRWLKQVGDSIQKDEPLIEVSTDKIATE 68

Query: 524 ITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 676
           ++    G++        +    G  L  +      +   PT V  + P+ E
Sbjct: 69  LSPSQAGVLEECLVQEGEEVSPGDVLARLREISPVDTSVPTSV-EESPIKE 118


>UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;
           Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
           acyltransferases - Thermoanaerobacter tengcongensis
          Length = 399

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 25/83 (30%), Positives = 39/83 (46%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +  GI   V+  WF   G  VQ  + + EVQ +KAA+ + +   GI+T++         V
Sbjct: 11  VSNGIEGFVVN-WFKDEGQPVQAGELLLEVQFEKAAIELQAPVSGILTKILCPQGHVVKV 69

Query: 590 GQPLVDIDVQDSENDGKPTDVAP 658
           GQ L  I+ + +E  G      P
Sbjct: 70  GQLLCLIEEKSTEVAGGSGSAVP 92


>UniRef50_Q0A5F2 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=2; Bacteria|Rep: Catalytic
           domain of components of various dehydrogenase complexes
           - Alkalilimnicola ehrlichei (strain MLHE-1)
          Length = 441

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           F +  +G  +    + EW V+ GD V++   I  V+++K A+ +     G++  LY +  
Sbjct: 4   FLMPSLGADMASGELVEWRVRPGDRVEKGQVIAVVETNKGAIEVEVFESGVVEALYEEPG 63

Query: 575 QTALVGQPLVDI----DVQDSENDGKPTDVAPDKPVAE 676
               VG P+  I     ++  E   KP      KP  E
Sbjct: 64  TRLPVGAPMARIGDGRGLEAGEGSPKPEPKPEPKPKPE 101


>UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;
           Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E2
           subunit - Nyctotherus ovalis
          Length = 485

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 5/132 (3%)
 Frame = +2

Query: 296 NGSQLSYKT-PLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNV 472
           N S L+ K+ P     S  +    +S+  +K++   L ++   + +  I +W+ K GD V
Sbjct: 28  NRSFLTVKSKPAQFPNSLGMARAFSSYPEHKVL--DLPNLSPTMTKGYITKWYKKEGDPV 85

Query: 473 QQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDIDVQDSENDGKPTD 649
              D IC+V++DKA V      DG+I + L  +  +   +G+P V I V ++++     D
Sbjct: 86  TAGDVICDVETDKATVGYEMVEDGVIAKILMPEGSKEVPLGKP-VAIMVTEAKDVAAFKD 144

Query: 650 VAPD---KPVAE 676
             P+   KP A+
Sbjct: 145 YKPEAAAKPAAK 156


>UniRef50_A7AMV7 Cluster: Biotin-requiring enzyme family protein;
           n=1; Babesia bovis|Rep: Biotin-requiring enzyme family
           protein - Babesia bovis
          Length = 177

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 22/79 (27%), Positives = 37/79 (46%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+  IG  ++   I++W  + GD V   D IC +++D+  V + S+  G I     +   
Sbjct: 85  KVPHIGRDVKHSKIQQWHKQRGDEVDVGDLICVLETDQVLVNVQSQLSGTIVETVGNEGC 144

Query: 578 TALVGQPLVDIDVQDSEND 634
              VG  L+ I     EN+
Sbjct: 145 RVKVGADLIIIRRPTEENE 163


>UniRef50_Q74Z83 Cluster: AGR323Cp; n=1; Eremothecium gossypii|Rep:
           AGR323Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 402

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R FH S A   I  F +  +   + +  I  W  KVG+  Q  D I EV++DKA + + +
Sbjct: 17  RPFHGSMAPRAITPFHMPAMSPTMEKGGIVSWKFKVGEPFQAGDVILEVETDKAQIDVEA 76

Query: 533 RYDG 544
           + DG
Sbjct: 77  QDDG 80


>UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex,
           dihydrolipoamide acetyltransferase E2 component; n=4;
           Deinococci|Rep: Pyruvate dehydrogenase complex,
           dihydrolipoamide acetyltransferase E2 component -
           Deinococcus radiodurans
          Length = 617

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           KL D+G+ I +  +    V  GD+V +   I E+++DKA V + +   G I  +   +  
Sbjct: 29  KLPDVGDNIEKGTVVTVLVNPGDSVTEGQPIIEIETDKAVVEVPASAAGTIEAVNVKVGD 88

Query: 578 TALVGQPLVDI-DVQDSENDGKPTDVAP 658
           T  VG  +  +     S +D  P+  AP
Sbjct: 89  TIPVGGVIATLGGGAASASDSAPSASAP 116



 Score = 38.7 bits (86), Expect = 0.13
 Identities = 23/87 (26%), Positives = 42/87 (48%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           L D+G+ I +  +    V VGD V +   + E+++DKA V + +   G +  +   I  +
Sbjct: 186 LPDVGDNIEKGTVVTILVNVGDTVSEGQPVIELETDKAVVEVPANASGTVQSVAVKIGDS 245

Query: 581 ALVGQPLVDIDVQDSENDGKPTDVAPD 661
             VG  ++ +    S    +PT  AP+
Sbjct: 246 IPVGGTILTLSGAAST---QPTAPAPE 269


>UniRef50_Q12FH2 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=3; Proteobacteria|Rep:
           Catalytic domain of components of various dehydrogenase
           complexes - Polaromonas sp. (strain JS666 / ATCC
           BAA-500)
          Length = 420

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 19/58 (32%), Positives = 33/58 (56%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           ++ FKL  +G  + E  + +W V+ GD V++   +  V + KAAV +    DG++T L
Sbjct: 1   MIEFKLPALGADMDEGTLLKWHVQPGDAVKRGQVVAVVDTSKAAVDVEIWQDGVMTEL 58


>UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase, putative; n=2; Basidiomycota|Rep:
           Dihydrolipoyllysine-residue acetyltransferase, putative
           - Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 479

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
 Frame = +2

Query: 353 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 532
           R   TS   N +  F +  +   + E  + +W  K G++    D + E+++DKA + + +
Sbjct: 24  RTLRTSAPSNVLSKFAMPAMSPTMTEGGVAQWKKKEGESFSAGDVLIEIETDKATIDVEA 83

Query: 533 RYDGIITRLY-HDIDQTALVGQPLVDI 610
           + DGI+ ++   D  +   VG P+  I
Sbjct: 84  QDDGIMAKIIAQDGTKNIAVGTPIAII 110


>UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase
           homoserine dehydrogenase; n=23; Alphaproteobacteria|Rep:
           Dihydrolipoamide acetyltransferase homoserine
           dehydrogenase - Rhizobium loti (Mesorhizobium loti)
          Length = 454

 Score = 39.5 bits (88), Expect = 0.073
 Identities = 24/78 (30%), Positives = 38/78 (48%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 616
           I  WF + G  V++ D + E+++DKAA+ I +   G++  +         VG P+  I  
Sbjct: 19  ISRWFAEEGARVKKGDVLFEIETDKAAMEIDAPASGVLRDVSGKEGVDIPVGAPVAWI-Y 77

Query: 617 QDSENDGKPTDVAPDKPV 670
            D E  G   D AP  P+
Sbjct: 78  ADDEAYGAKQDAAPISPL 95


>UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3;
           Gammaproteobacteria|Rep: Dihydrolipoamide
           acetyltransferase - Acinetobacter sp. (strain ADP1)
          Length = 513

 Score = 39.5 bits (88), Expect = 0.073
 Identities = 19/87 (21%), Positives = 44/87 (50%), Gaps = 3/87 (3%)
 Frame = +2

Query: 377 VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR 556
           +++I   ++   G  + E  + +W ++ G + ++ D ICE+++ K    + + +DG + +
Sbjct: 1   MSEIKTLEIPKWGLSMEEGTVAQWLIEEGTSFKKGDEICEIETTKIVNVLEAPFDGTLRQ 60

Query: 557 LYHDIDQTALVGQPL---VDIDVQDSE 628
           +      T  VG  +    + DV D+E
Sbjct: 61  ILAHAGDTLPVGGLIAICAEADVSDTE 87


>UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of
           branched-chain alpha-ketoacid dehydrogenase complex;
           n=1; Croceibacter atlanticus HTCC2559|Rep: Lipoamide
           acyltransferase component of branched-chain
           alpha-ketoacid dehydrogenase complex - Croceibacter
           atlanticus HTCC2559
          Length = 480

 Score = 39.5 bits (88), Expect = 0.073
 Identities = 19/74 (25%), Positives = 36/74 (48%)
 Frame = +2

Query: 392 AFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDI 571
           AFK+  +GE I E  I  W V+ GD  ++ D + E+ +DK    + + + G++       
Sbjct: 5   AFKVPKMGESITEGTIINWVVQEGDAFEEGDILVEIATDKVDNEVPAPFSGVMISHKAQA 64

Query: 572 DQTALVGQPLVDID 613
           +    VG  +  ++
Sbjct: 65  NDVVAVGSEIAILE 78


>UniRef50_A1SN86 Cluster: Biotin/lipoyl attachment domain-containing
           protein; n=2; Actinomycetales|Rep: Biotin/lipoyl
           attachment domain-containing protein - Nocardioides sp.
           (strain BAA-499 / JS614)
          Length = 78

 Score = 39.5 bits (88), Expect = 0.073
 Identities = 20/62 (32%), Positives = 31/62 (50%)
 Frame = +2

Query: 428 EVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVD 607
           E V+  WFV+ G+ V     I EVQ DK A  + +   G++  L+ + +     G P+  
Sbjct: 17  EGVVSTWFVREGETVTADQLIAEVQVDKVAAEVPAPVGGVVHLLFEE-EAAVAQGTPIAR 75

Query: 608 ID 613
           ID
Sbjct: 76  ID 77


>UniRef50_A1R7P9 Cluster: Biotin / lipoyl attachment domain protein;
           n=1; Arthrobacter aurescens TC1|Rep: Biotin / lipoyl
           attachment domain protein - Arthrobacter aurescens
           (strain TC1)
          Length = 90

 Score = 39.5 bits (88), Expect = 0.073
 Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
 Frame = +2

Query: 443 EWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQD 622
           +W V+ G  V++   I E+++ K+A+ + S   G + R++     T  VG+PL+  +V D
Sbjct: 3   DWLVEPGQQVERNQAIVELETTKSALELPSPQAGKVVRIHGAPGDTINVGEPLIVFEVPD 62

Query: 623 SEN---DGKPTDVAPDKPV 670
                    P D AP + V
Sbjct: 63  DTAGIVGTVPKDEAPKRRV 81


>UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of pyruvate dehydrogenase
           complex; n=11; Proteobacteria|Rep:
           Dihydrolipoyllysine-residue acetyltransferase component
           of pyruvate dehydrogenase complex - Haemophilus
           influenzae
          Length = 567

 Score = 39.5 bits (88), Expect = 0.073
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           ++ DIG    EV + E  V VGD +    +I  V+ DKA++ + +   G++  +   +  
Sbjct: 6   QIPDIGSD--EVTVTEVMVNVGDTISVDQSIINVEGDKASMEVPAPEAGVVKEILVKVGD 63

Query: 578 TALVGQPLVDIDVQDSENDG-KPTDVAPDKPVA 673
               G P++ ++   +     +PT    D P A
Sbjct: 64  KVSTGTPMLVLEAAGAAPAADEPTAPVADAPTA 96



 Score = 35.9 bits (79), Expect = 0.90
 Identities = 18/65 (27%), Positives = 35/65 (53%)
 Frame = +2

Query: 365 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 544
           T+   + IV   + DIG    EV + E  V VGD + +  ++  V+ DKA++ + + + G
Sbjct: 101 TAPTASAIVEVNVPDIGGD--EVNVTEIMVAVGDTITEEQSLITVEGDKASMEVPAPFGG 158

Query: 545 IITRL 559
           ++  +
Sbjct: 159 VVKEI 163


>UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2;
           Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
           kaustophilus
          Length = 436

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 25/84 (29%), Positives = 38/84 (45%)
 Frame = +2

Query: 386 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           +V   L  + +   E  I  W V  GD V++   + EVQ++KA   I +   G +  +  
Sbjct: 2   VVEVTLPKLSDSHDESFITFWHVSEGDAVEKGATLVEVQTEKAVSEIHAPESGTVKEIKK 61

Query: 566 DIDQTALVGQPLVDIDVQDSENDG 637
               TA VG+ L  I V+    DG
Sbjct: 62  KRGDTAKVGEVLAVIAVETFAPDG 85


>UniRef50_Q057U1 Cluster: Pyruvate dehydrogenase E2 component; n=1;
           Buchnera aphidicola str. Cc (Cinara cedri)|Rep: Pyruvate
           dehydrogenase E2 component - Buchnera aphidicola subsp.
           Cinara cedri
          Length = 417

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 24/84 (28%), Positives = 43/84 (51%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 568
           V  ++ DIG  I++V + E FVK GD V + D++  V+  K+ + I S   GII ++   
Sbjct: 3   VEVRVPDIG--IKDVEVIEIFVKKGDIVSKEDSLISVEGHKSVLEIPSPISGIIKKICTQ 60

Query: 569 IDQTALVGQPLVDIDVQDSENDGK 640
           +     + + ++ I+     N  K
Sbjct: 61  VGDKLSIDKLILIINNNQENNISK 84


>UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 396

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 13/41 (31%), Positives = 26/41 (63%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           I  W  K GD ++  D +CE+++DKA +T+ +   G++ ++
Sbjct: 13  IVSWLKKEGDTIEPGDALCEIETDKATLTLDTDEQGVLAKI 53


>UniRef50_P16451 Cluster: Pyruvate dehydrogenase complex protein X
           component, mitochondrial precursor; n=3; Saccharomyces
           cerevisiae|Rep: Pyruvate dehydrogenase complex protein X
           component, mitochondrial precursor - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 410

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
 Frame = +2

Query: 356 HFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSR 535
           ++H S  +  +  F +  +   + +  I  W  KVG+     D I EV++DK+ + + + 
Sbjct: 22  NYHASAKLLAVKTFSMPAMSPTMEKGGIVSWKYKVGEPFSAGDVILEVETDKSQIDVEAL 81

Query: 536 YDGIITRLYHDIDQTAL-VGQPLVDI-DVQD 622
            DG + ++  D     + VG+P+  I DV D
Sbjct: 82  DDGKLAKILKDEGSKDVDVGEPIAYIADVDD 112


>UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta; n=99; Bacteria|Rep: Pyruvate dehydrogenase
           E1 component subunit beta - Zymomonas mobilis
          Length = 462

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 24/100 (24%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
 Frame = +2

Query: 389 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYH 565
           +  K+  +   + E  +  W VK GD+++  + + E+++DKA +   +  +G+IT+ L  
Sbjct: 3   IELKMPALSPTMEEGTLTRWLVKEGDSIKAGEILAEIETDKAIMEFEAVDEGVITKILIP 62

Query: 566 DIDQTALVGQPL--VDIDVQDSENDGKPTDVAPDK--PVA 673
           +  +   VG  +  +  D  D   DG   +   ++  PVA
Sbjct: 63  EGSENVKVGTAIAYLGTDANDVTLDGASAETKAEESAPVA 102


>UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase
           component; n=6; Anaplasmataceae|Rep: Dihydrolipoamide
           acetyltransferase component - Anaplasma marginale
           (strain St. Maries)
          Length = 437

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
 Frame = +2

Query: 389 VAFKLSDIG-EGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 565
           V  K+ ++G E I E  ++    KVGD V   + +  V++DK ++ I S   G+IT L  
Sbjct: 28  VEIKVDNLGGESISEAPVRV-LKKVGDAVSAEEAVFIVETDKTSLEIASPVAGVITELRV 86

Query: 566 DIDQTALVGQPLVDIDVQDSENDGKPTDVA 655
             ++    GQ L  I    S+++G P D A
Sbjct: 87  SDEEIVTRGQVLAII----SKHEGAPQDAA 112


>UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=42;
           Bacteria|Rep: Dihydrolipoamide acetyltransferase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 548

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 21/72 (29%), Positives = 41/72 (56%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 577
           K+ DIG+  ++V + E  VKVGD V++  ++  ++SDKA + + S   G++  +   +  
Sbjct: 122 KVPDIGD-YKDVPVIEIGVKVGDTVEKEQSLVTLESDKATMDVPSPAAGVVKEIKVKVGD 180

Query: 578 TALVGQPLVDID 613
           +   G  +V +D
Sbjct: 181 SVSEGTLIVLLD 192



 Score = 38.3 bits (85), Expect = 0.17
 Identities = 19/76 (25%), Positives = 42/76 (55%)
 Frame = +2

Query: 377 VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR 556
           +++ +  K+ DIG+  ++V + E  VKVGD V+   ++  ++SDKA + + S   G++  
Sbjct: 1   MSQAIEVKVPDIGD-YKDVPVIEIGVKVGDTVEPEQSLVTLESDKATMDVPSPVGGVVKE 59

Query: 557 LYHDIDQTALVGQPLV 604
           +   +  +   G  ++
Sbjct: 60  IKVKVGDSVSEGSLII 75


>UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic domain
           of components of various dehydrogenase complexes:E3
           binding; n=2; Thermoanaerobacter ethanolicus|Rep:
           Biotin/lipoyl attachment:Catalytic domain of components
           of various dehydrogenase complexes:E3 binding -
           Thermoanaerobacter ethanolicus ATCC 33223
          Length = 382

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 19/64 (29%), Positives = 34/64 (53%)
 Frame = +2

Query: 410 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 589
           +G  ++E  +  W  KVGD V++ + I EV +DK    + S  DGI+ ++  +  +   V
Sbjct: 10  LGLTMKEGRVDRWLKKVGDIVKKGEEIVEVSTDKITNVVESPADGILAKILVNEGEIVPV 69

Query: 590 GQPL 601
             P+
Sbjct: 70  ATPI 73


>UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1;
           Acidobacteria bacterium Ellin345|Rep: Dihydrolipoamide
           acetyltransferase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 615

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 20/85 (23%), Positives = 40/85 (47%)
 Frame = +2

Query: 368 SHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGI 547
           S    + + FKL ++GE I++  +     K G +V     I E+++DKA + + +   G 
Sbjct: 119 STGTKQTIEFKLPELGENIKQGQLVRIIAKQGASVSDGQPILELETDKAVIEVPATLTGT 178

Query: 548 ITRLYHDIDQTALVGQPLVDIDVQD 622
           I  ++        VGQ +  ++  +
Sbjct: 179 IKEVHVKEGDKIGVGQTIFTVETTE 203



 Score = 37.9 bits (84), Expect = 0.22
 Identities = 20/66 (30%), Positives = 33/66 (50%)
 Frame = +2

Query: 395 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 574
           FKL ++GE I    +    VK GD V++   + E+++DKA + + S   G +  +     
Sbjct: 5   FKLPELGENIASGDLVRVMVKPGDTVKEGQPVIELETDKAVIEVPSTVSGKVQEVKVQKG 64

Query: 575 QTALVG 592
           Q   VG
Sbjct: 65  QKLKVG 70


>UniRef50_Q1AT73 Cluster: Catalytic domain of components of various
           dehydrogenase complexes; n=1; Rubrobacter xylanophilus
           DSM 9941|Rep: Catalytic domain of components of various
           dehydrogenase complexes - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 441

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 2/94 (2%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 580
           +  +GE + E  I  W    GD V++ + I EV +DK +  + S   G I RL      T
Sbjct: 7   MPQLGESVTEGTIARWLKAEGDEVEKDEPIAEVDTDKVSAELPSPLAGRIERLLVPEGAT 66

Query: 581 ALVGQPLVDIDVQDSENDGKPT--DVAPDKPVAE 676
             VG  +  +   +      P   D   + P  E
Sbjct: 67  VEVGTEIALVATGEEPGPDGPAREDARSEGPTEE 100


>UniRef50_A6X6G3 Cluster: Biotin/lipoyl attachment domain protein;
           n=1; Ochrobactrum anthropi ATCC 49188|Rep: Biotin/lipoyl
           attachment domain protein - Ochrobactrum anthropi
           (strain ATCC 49188 / DSM 6882 / NCTC 12168)
          Length = 443

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 23/79 (29%), Positives = 36/79 (45%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 616
           I  W+ K GD V +   + E+++DKAA+ + +   GII  +         VGQ +  I  
Sbjct: 19  ISRWYAKDGDTVTKGQLLFEIETDKAAMEVDAPASGIIADISAAEGTVVPVGQTVAWIYD 78

Query: 617 QDSENDGKPTDVAPDKPVA 673
           +  E   K   V  +  VA
Sbjct: 79  EGEERSAKSAPVVEEPIVA 97


>UniRef50_A4SZ52 Cluster: Catalytic domain of components of various
           dehydrogenase complexes precursor; n=1; Polynucleobacter
           sp. QLW-P1DMWA-1|Rep: Catalytic domain of components of
           various dehydrogenase complexes precursor -
           Polynucleobacter sp. QLW-P1DMWA-1
          Length = 472

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 22/86 (25%), Positives = 46/86 (53%)
 Frame = +2

Query: 407 DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTAL 586
           DIG+  + + + E  V+VGD +++  +I  ++SDKA + + S + GI+  +   I     
Sbjct: 43  DIGD-YQNIPVIEVLVQVGDQIEKEQSILTLESDKATMDVPSSHSGIVKEIKVKIGDLLS 101

Query: 587 VGQPLVDIDVQDSENDGKPTDVAPDK 664
            G+ ++ ++      DG P+D   ++
Sbjct: 102 QGKSVIVLE------DGLPSDATSNE 121


>UniRef50_A2VX19 Cluster: Pyruvate dehydrogenase complex,
           dehydrogenase (E1) component; n=1; Burkholderia
           cenocepacia PC184|Rep: Pyruvate dehydrogenase complex,
           dehydrogenase (E1) component - Burkholderia cenocepacia
           PC184
          Length = 526

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 23/100 (23%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
 Frame = +2

Query: 377 VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR 556
           +++ +  K+ DIG+  ++V + E  VKVGD V+   ++  ++SDKA + + S   G++  
Sbjct: 1   MSQAIEVKVPDIGD-YKDVPVIEIGVKVGDTVEPEQSLVTLESDKATMDVPSPVGGVVKE 59

Query: 557 LYHDIDQTALVGQPLVDID-VQDSENDGKPTDVAPDKPVA 673
           +   +  +   G  ++ ++    ++ +G     A   P A
Sbjct: 60  IKVKVGDSVSEGSLIILLEGGAGAQANGAAAPAAAPAPAA 99



 Score = 36.3 bits (80), Expect = 0.68
 Identities = 18/51 (35%), Positives = 33/51 (64%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGII 550
           K+ DIG+  ++V + E  VKVGD V++  ++  ++SDKA + + S   G++
Sbjct: 122 KVPDIGD-YKDVPVIEIGVKVGDTVEKEQSLVTLESDKATMDVPSPAAGVV 171


>UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component 1 of pyruvate dehydrogenase
           complex, mitochondrial precursor; n=4;
           Magnoliophyta|Rep: Dihydrolipoyllysine-residue
           acetyltransferase component 1 of pyruvate dehydrogenase
           complex, mitochondrial precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 637

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 14/41 (34%), Positives = 26/41 (63%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           + +W  K GD V+  D +CE+++DKA V   S+ +G + ++
Sbjct: 102 VVKWMKKEGDKVEVGDVLCEIETDKATVEFESQEEGFLAKI 142



 Score = 37.9 bits (84), Expect = 0.22
 Identities = 21/66 (31%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDID 613
           I +W+ K GD ++  D I E+++DKA +   S  +G + + L  +  +   VG+P+  I 
Sbjct: 229 IAKWWKKEGDKIEVGDVIGEIETDKATLEFESLEEGYLAKILIPEGSKDVAVGKPIALI- 287

Query: 614 VQDSEN 631
           V+D+E+
Sbjct: 288 VEDAES 293


>UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;
           n=2; Deinococcus|Rep: 2-oxo acid dehydrogenase, E2
           component - Deinococcus radiodurans
          Length = 525

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
 Frame = +2

Query: 401 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGII-TRLYHDIDQ 577
           L ++ E + E  I +W V+ GD +     +CEV +DK  V + S ++G +  R+ ++ D 
Sbjct: 6   LPELAESVVEGEILKWLVEEGDAIALEQPLCEVMTDKVTVELPSPFEGTLHKRMANEGDV 65

Query: 578 TAL 586
            A+
Sbjct: 66  VAV 68


>UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 component;
           n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
           2-oxoglutarate dehydrogenase E2 component - Buchnera
           aphidicola subsp. Cinara cedri
          Length = 398

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 19/65 (29%), Positives = 38/65 (58%)
 Frame = +2

Query: 407 DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTAL 586
           ++ E +   ++ +W  K+GD V++ + I E+++DK  + I+S  +GI+      I Q  L
Sbjct: 11  NLPESVNHAIMLKWNKKIGDYVKEDEIIAEIETDKIILEISSPKNGIL------ISQNIL 64

Query: 587 VGQPL 601
           VG+ +
Sbjct: 65  VGEKI 69


>UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Dihydrolipoamide
           acetyltransferase - Lentisphaera araneosa HTCC2155
          Length = 415

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 19/67 (28%), Positives = 40/67 (59%)
 Frame = +2

Query: 413 GEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVG 592
           GE + E  I  WF + G+ ++  + + E+++DKA++TIT+   G +  +  + D+T  VG
Sbjct: 11  GESVTEADIARWFKEDGEFLELDEPMVELETDKASLTITAPAAGTL-HIKVEEDETVQVG 69

Query: 593 QPLVDID 613
           + +  ++
Sbjct: 70  EVIAVLE 76


>UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 549

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 20/66 (30%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDID 613
           I +W  + G+ ++  D ICE+++DKA +   S  +G + + L  +  +   VGQP+  + 
Sbjct: 168 IAKWRKQEGEKIEVGDVICEIETDKATLEFESLEEGYLAKILAPEGSKDVQVGQPIA-VT 226

Query: 614 VQDSEN 631
           V+D E+
Sbjct: 227 VEDLED 232


>UniRef50_Q97Y20 Cluster: Dihydrolipoamide S-acetyltransferase,
           amino-end; n=1; Sulfolobus solfataricus|Rep:
           Dihydrolipoamide S-acetyltransferase, amino-end -
           Sulfolobus solfataricus
          Length = 211

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 20/73 (27%), Positives = 36/73 (49%)
 Frame = +2

Query: 437 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 616
           I +W  K GD VQ+ +++  ++++K   T+ S   GI+ ++Y    +   VGQ +  I  
Sbjct: 19  IVQWKKKEGDRVQEGEDLVIIETEKITTTVKSPVSGILLKIYAKEGEEVPVGQIIAYIGE 78

Query: 617 QDSENDGKPTDVA 655
              +    PT  A
Sbjct: 79  IGEQPPPSPTKPA 91


>UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue
           succinyltransferase component of 2- oxoglutarate
           dehydrogenase complex; n=79; Bacteria|Rep:
           Dihydrolipoyllysine-residue succinyltransferase
           component of 2- oxoglutarate dehydrogenase complex -
           Bartonella quintana (Rochalimaea quintana)
          Length = 410

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 16/54 (29%), Positives = 31/54 (57%)
 Frame = +2

Query: 398 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 559
           ++  +GE + E  I +WF K+G+ V   + + E+++DK  V + S   G +T +
Sbjct: 6   RVPTLGESVTEATIGKWFKKLGEAVAVDEPLVELETDKVTVEVPSPVMGKLTEI 59


>UniRef50_Q59695 Cluster: Dihydrolipoyllysine-residue
           acetyltransferase component of acetoin cleaving system;
           n=7; Bacteria|Rep: Dihydrolipoyllysine-residue
           acetyltransferase component of acetoin cleaving system -
           Pseudomonas putida
          Length = 370

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
 Frame = +2

Query: 413 GEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVG 592
           G  + E  +  W  + GD + + D + +V++DK + ++ + + G++ R     D+T  VG
Sbjct: 13  GLSMTEGRVDAWLKQEGDEINKGDEVLDVETDKISSSVEAPFSGVLRRQVAKPDETLPVG 72

Query: 593 QPL---VDIDVQDSEND 634
             L   V+ + ++SE D
Sbjct: 73  ALLAVVVEGEAEESEID 89


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 615,211,665
Number of Sequences: 1657284
Number of extensions: 11774254
Number of successful extensions: 32380
Number of sequences better than 10.0: 353
Number of HSP's better than 10.0 without gapping: 31203
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32358
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 52066120554
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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