Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Nnor0036
(682 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 231 9e-60
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 229 4e-59
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 207 2e-52
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 206 4e-52
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 206 5e-52
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 186 3e-46
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 185 8e-46
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 184 2e-45
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 176 4e-43
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 167 2e-40
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 161 2e-38
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 158 1e-37
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 156 4e-37
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 149 5e-35
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 149 5e-35
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 132 1e-29
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 131 1e-29
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 130 3e-29
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 125 1e-27
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 125 1e-27
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 122 1e-26
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 118 1e-25
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 118 1e-25
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz... 113 3e-24
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 105 8e-22
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 102 7e-21
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org... 101 2e-20
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr... 91 2e-17
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 89 9e-17
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 84 3e-15
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 81 2e-14
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 79 1e-13
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 78 2e-13
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 78 2e-13
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 77 3e-13
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 77 4e-13
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 77 5e-13
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 76 7e-13
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 76 7e-13
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 76 9e-13
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 75 2e-12
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 74 3e-12
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr... 74 4e-12
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 74 4e-12
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 73 5e-12
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 73 5e-12
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000... 73 6e-12
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 73 6e-12
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 73 6e-12
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 73 9e-12
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 72 2e-11
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 70 6e-11
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 70 6e-11
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 69 8e-11
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 69 1e-10
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 68 2e-10
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 68 2e-10
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 68 2e-10
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 66 6e-10
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 66 7e-10
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 66 7e-10
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 66 7e-10
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 66 7e-10
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 65 1e-09
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 65 1e-09
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 65 1e-09
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 64 3e-09
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 64 3e-09
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 64 4e-09
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 64 4e-09
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 64 4e-09
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 64 4e-09
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 63 7e-09
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 63 7e-09
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 62 9e-09
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 62 9e-09
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 60 4e-08
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 60 5e-08
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 60 6e-08
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 59 9e-08
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 59 9e-08
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 59 9e-08
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 58 1e-07
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 58 1e-07
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 58 1e-07
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace... 57 3e-07
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 57 3e-07
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 57 5e-07
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 56 6e-07
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 56 6e-07
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 56 6e-07
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 56 8e-07
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 56 8e-07
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 56 1e-06
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 55 1e-06
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 54 2e-06
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 54 3e-06
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 54 3e-06
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 53 7e-06
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 52 1e-05
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 52 1e-05
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 52 1e-05
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 52 1e-05
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 52 2e-05
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 51 2e-05
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 51 2e-05
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 51 2e-05
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 50 4e-05
UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate DeH... 50 5e-05
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 49 1e-04
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 49 1e-04
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 48 2e-04
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 48 2e-04
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 48 3e-04
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 47 4e-04
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 47 4e-04
UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 47 4e-04
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ... 47 5e-04
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 46 0.001
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 46 0.001
UniRef50_Q014D4 Cluster: Chromosome 08 contig 1, DNA sequence; n... 45 0.002
UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n... 44 0.003
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 44 0.003
UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 44 0.003
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 44 0.005
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 44 0.005
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 44 0.005
UniRef50_O34358 Cluster: Probable serine protease do-like htrA; ... 43 0.006
UniRef50_UPI00015974E8 Cluster: HtrA; n=1; Bacillus amyloliquefa... 43 0.008
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 43 0.008
UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1; Staphyloc... 42 0.011
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 42 0.014
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 42 0.018
UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to Ecdysone-i... 41 0.024
UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 41 0.032
UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3; Bifidob... 41 0.032
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.056
UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 38 0.23
UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1; ... 37 0.52
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 36 0.69
UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 36 0.91
UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finge... 36 1.2
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 36 1.2
UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-... 35 1.6
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 35 1.6
UniRef50_Q8NQ95 Cluster: Predicted nucleoside-diphosphate-sugar ... 35 2.1
UniRef50_UPI000049A32B Cluster: protein kinase; n=1; Entamoeba h... 34 2.8
UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n... 34 2.8
UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9; ... 34 2.8
UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;... 34 3.7
UniRef50_Q81Y95 Cluster: Serine protease; n=16; Bacillaceae|Rep:... 34 3.7
UniRef50_Q608X6 Cluster: Hydrophobe/amphiphile Efflux-1 (HAE1) f... 34 3.7
UniRef50_A6ESK5 Cluster: LysM-repeat protein; n=1; unidentified ... 34 3.7
UniRef50_A6CMQ6 Cluster: HtrA; n=1; Bacillus sp. SG-1|Rep: HtrA ... 34 3.7
UniRef50_Q9VY98 Cluster: CG9941-PA; n=5; Drosophila|Rep: CG9941-... 34 3.7
UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3; Lactoco... 34 3.7
UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome sh... 33 4.9
UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein precur... 33 4.9
UniRef50_Q0JLJ7 Cluster: Os01g0595100 protein; n=6; Oryza sativa... 33 4.9
UniRef50_A2XSM8 Cluster: Putative uncharacterized protein; n=2; ... 33 4.9
UniRef50_Q2UFR5 Cluster: Predicted protein; n=2; Aspergillus|Rep... 33 4.9
UniRef50_A2R1L8 Cluster: Contig An13c0060, complete genome; n=2;... 33 4.9
UniRef50_Q46780 Cluster: BfpF; n=4; Enterobacteriaceae|Rep: BfpF... 33 6.4
UniRef50_Q0SBH8 Cluster: Pyruvate dehydrogenase E1 component; n=... 33 6.4
UniRef50_UPI0000D9F76A Cluster: PREDICTED: hypothetical protein,... 33 8.5
UniRef50_Q91LF0 Cluster: ORF90; n=1; Shrimp white spot syndrome ... 33 8.5
UniRef50_A7SI71 Cluster: Predicted protein; n=1; Nematostella ve... 33 8.5
UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone demethyl... 33 8.5
>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=514; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Mus musculus
(Mouse)
Length = 338
Score = 231 bits (566), Expect = 9e-60
Identities = 115/192 (59%), Positives = 143/192 (74%)
Frame = +2
Query: 71 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 250
M S +PA A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 251 IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 430
IA TPGVAADLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58 IAH-TPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116
Query: 431 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVR 610
NA+IV + + AQ+ P+A+V II NPVNST+PI +EV KK GVY+PN++ GVTTLD+VR
Sbjct: 117 NATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVR 176
Query: 611 AATFVGEINGVD 646
A TFV E+ G+D
Sbjct: 177 ANTFVAELKGLD 188
>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=119; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 338
Score = 229 bits (561), Expect = 4e-59
Identities = 112/192 (58%), Positives = 143/192 (74%)
Frame = +2
Query: 71 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 250
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 251 IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNT 430
IA TPGVAADLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNT
Sbjct: 58 IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116
Query: 431 NASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVR 610
NA+IV + + AQ+ P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+VR
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVR 176
Query: 611 AATFVGEINGVD 646
A TFV E+ G+D
Sbjct: 177 ANTFVAELKGLD 188
>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
glyoxysomal precursor - Oryza sativa subsp. japonica
(Rice)
Length = 356
Score = 207 bits (506), Expect = 2e-52
Identities = 105/165 (63%), Positives = 121/165 (73%)
Frame = +2
Query: 152 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGP 331
FK IGQPLALL+K NPLV+ L LYD+ TPGV AD+SHMNT A V G G
Sbjct: 45 FKVAILGASGGIGQPLALLMKMNPLVSVLHLYDVVN-TPGVTADISHMNTGAVVRGFLGQ 103
Query: 332 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 511
+L A+ D+V+IPAGVPRKPGMTRDDLFN NA IVR + IA+ P AIV +I+NP
Sbjct: 104 PQLENALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLCEGIAKCCPNAIVNVISNP 163
Query: 512 VNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
VNSTVPIA+EV KKAG YDP R+LGVTTLDVVRA TFV E+ G+D
Sbjct: 164 VNSTVPIAAEVFKKAGTYDPKRLLGVTTLDVVRANTFVAEVLGLD 208
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 206 bits (503), Expect = 4e-52
Identities = 100/149 (67%), Positives = 121/149 (81%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 364
IGQPL+LL+K +PLV+ L LYDIA V GVAADLSH NTP++V GP EL+ +KD +
Sbjct: 94 IGQPLSLLIKMSPLVSTLHLYDIANVK-GVAADLSHCNTPSQVRDFTGPSELADCLKDVN 152
Query: 365 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 544
VVVIPAGVPRKPGMTRDDLFN NA+IV+ + ++A+N P A + II+NPVNSTVPIA+EV
Sbjct: 153 VVVIPAGVPRKPGMTRDDLFNINANIVKTLVEAVAENCPNAFIHIISNPVNSTVPIAAEV 212
Query: 545 LKKAGVYDPNRVLGVTTLDVVRAATFVGE 631
LKK GVYDP ++ GVTTLDVVRA TFV +
Sbjct: 213 LKKKGVYDPKKLFGVTTLDVVRANTFVSQ 241
>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Aspergillus niger
Length = 340
Score = 206 bits (502), Expect = 5e-52
Identities = 101/176 (57%), Positives = 133/176 (75%), Gaps = 1/176 (0%)
Frame = +2
Query: 122 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNT 301
++FS ++ + K IGQPL+LL+KQNPLVT LALYDI PGVAAD+SH+NT
Sbjct: 14 RSFSASASQASKVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDIRG-GPGVAADISHINT 72
Query: 302 PAKVSGHKG-PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 478
+ V G++ P L A+K +++++IPAGVPRKPGMTRDDLFNTNASIVRD+A + A+ A
Sbjct: 73 NSTVKGYEPTPSGLRDALKGSEIILIPAGVPRKPGMTRDDLFNTNASIVRDLAKAAAEAA 132
Query: 479 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
P+A + +I+NPVNSTVPI SEV K GVY+P R+ GVTTLDVVRA+ F+ ++ G +
Sbjct: 133 PEANILVISNPVNSTVPIVSEVYKSKGVYNPKRLFGVTTLDVVRASRFISQVKGTN 188
>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 186 bits (454), Expect = 3e-46
Identities = 87/121 (71%), Positives = 106/121 (87%)
Frame = +2
Query: 269 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 448
GVAADLSH++T AKV+ H+GP++L AA++ VV IPAGVPRKPGMTRDDLFNTNASIV+
Sbjct: 7 GVAADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVK 66
Query: 449 DIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVG 628
+++ + A++ PKAI+ II+NPVNSTVPIASEV KKAGVYDP R+LGVTTLD+VRA TFV
Sbjct: 67 NLSEACAKHCPKAIICIISNPVNSTVPIASEVYKKAGVYDPARILGVTTLDIVRAHTFVA 126
Query: 629 E 631
E
Sbjct: 127 E 127
>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
Malate dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 341
Score = 185 bits (451), Expect = 8e-46
Identities = 94/175 (53%), Positives = 122/175 (69%), Gaps = 2/175 (1%)
Frame = +2
Query: 122 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNT 301
++FSTTS R FK IGQPL++LLK N V+ LAL+DI PGVAAD+ H+NT
Sbjct: 19 RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRGA-PGVAADIGHINT 77
Query: 302 PAKVSGHKGPEE-LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 478
+ V G+ ++ L A+ ADVV+IPAGVPRKPGMTRDDLF TNASIVRD+A + +
Sbjct: 78 TSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAFAAGETC 137
Query: 479 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEI-NG 640
P+A ++TNPVNSTVPI + L++ GV+ P + GVTTLD VRA+ F ++ NG
Sbjct: 138 PEAKYLVVTNPVNSTVPIFKKALERVGVHQPKHLFGVTTLDSVRASRFTSQVTNG 192
>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
Malate dehydrogenase - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 346
Score = 184 bits (448), Expect = 2e-45
Identities = 93/155 (60%), Positives = 120/155 (77%), Gaps = 5/155 (3%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEE-----LSAA 349
IGQPL+LLLK NP V+ L+L+D+ GVAADLSH+ +PAKV+G++ + + A
Sbjct: 13 IGQPLSLLLKLNPQVSELSLFDVVNAN-GVAADLSHICSPAKVTGYQPSSKEDRDTIQKA 71
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
+ ++D+VVIPAGVPRKPGMTR DLFN NASI+RDI SI + P A + II+NPVNSTVP
Sbjct: 72 LVNSDLVVIPAGVPRKPGMTRADLFNINASIIRDIVGSIGKACPNAAILIISNPVNSTVP 131
Query: 530 IASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEI 634
IA+EVLKK GV++P ++ GVTTLD VRA TF+GE+
Sbjct: 132 IAAEVLKKLGVFNPKKLFGVTTLDSVRAETFLGEL 166
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 176 bits (429), Expect = 4e-43
Identities = 88/167 (52%), Positives = 112/167 (67%)
Frame = +2
Query: 146 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHK 325
R K IGQPL+LLLK NP ++ L+LYDI T GV DLSH+NT A V +
Sbjct: 26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTT-GVGVDLSHINTRASVCPFE 84
Query: 326 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 505
G L A+ AD+VVIPAG+PRKPGM R+DL + NAS+ ++A + ++ P A++A IT
Sbjct: 85 GKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFIT 144
Query: 506 NPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
NP+N VPI + +LK G YDPNR+ GVTTLDVVRA TFV +I VD
Sbjct: 145 NPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVD 191
>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
glabrata|Rep: Malate dehydrogenase - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 373
Score = 167 bits (407), Expect = 2e-40
Identities = 81/149 (54%), Positives = 111/149 (74%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 364
+GQPL+LLLK N +++ LALYDI + GVA DLSH+NT A G+ +++ A+K A
Sbjct: 13 VGQPLSLLLKLNTMISELALYDIK-LAEGVATDLSHINTNADCVGYS-TDDIGQALKGAA 70
Query: 365 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 544
VVVIPAGVPR+PG+TRDDLF NA IV+++ ++A++ P A + II+NPVNS +P+A E
Sbjct: 71 VVVIPAGVPRRPGITRDDLFKLNAGIVKNLVSNVAKHCPNARLLIISNPVNSLIPVAVET 130
Query: 545 LKKAGVYDPNRVLGVTTLDVVRAATFVGE 631
LK+ GV+ V+GVTTLD+VRA TF+ E
Sbjct: 131 LKRCGVFQAGNVMGVTTLDLVRAETFLAE 159
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 161 bits (390), Expect = 2e-38
Identities = 81/166 (48%), Positives = 116/166 (69%), Gaps = 1/166 (0%)
Frame = +2
Query: 152 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHKG 328
FK IGQPLAL L QN V+ LALYDI V P GVA DLSH KV+G+
Sbjct: 9 FKVTVLGASGAIGQPLALALVQNKRVSELALYDI--VQPRGVAVDLSHFPRKVKVTGYP- 65
Query: 329 PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITN 508
+ + A+ AD+V++ AG+PR+PGMT DDLFNTNA V +++ ++A+ APK+++AII+N
Sbjct: 66 TKWIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSAAVARYAPKSVLAIISN 125
Query: 509 PVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
P+NS VP+A+E L++AGVYDP ++ G+ +L+++RA +G+ G D
Sbjct: 126 PLNSMVPVAAETLQRAGVYDPRKLFGIISLNMMRARKMLGDFTGQD 171
>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 158 bits (383), Expect = 1e-37
Identities = 77/147 (52%), Positives = 103/147 (70%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 364
+GQPL+LLLK +P V+ LALYDI G+ DLSH+NT + G+ + + + +A
Sbjct: 13 VGQPLSLLLKLSPYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYD-KDSIENTLSNAQ 70
Query: 365 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 544
VV+IPAGVPRKPG+TRDDLF NA IV+ + ++ + AP A + +I+NPVNS VPIA E
Sbjct: 71 VVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVET 130
Query: 545 LKKAGVYDPNRVLGVTTLDVVRAATFV 625
LKK G + P V+GVT LD+VRA TF+
Sbjct: 131 LKKMGKFKPGNVMGVTNLDLVRAETFL 157
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 156 bits (379), Expect = 4e-37
Identities = 72/151 (47%), Positives = 108/151 (71%), Gaps = 1/151 (0%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 364
IGQPL+LLLK NP V+ LALYDI+ +T GVA DLSH+NT + G+ E+ ++ ++
Sbjct: 13 IGQPLSLLLKLNPYVSDLALYDISDITAGVAKDLSHINTNSDSEGYNKDEDFKNLLEGSE 72
Query: 365 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAP-KAIVAIITNPVNSTVPIASE 541
+V++ AG+PRKPGMTRDDLF NA I++++ + A+ AP + II+NPVNS +P+ E
Sbjct: 73 LVIVTAGIPRKPGMTRDDLFKINAKIIQNLTVKYAKFAPVHCKLLIISNPVNSLIPVVIE 132
Query: 542 VLKKAGVYDPNRVLGVTTLDVVRAATFVGEI 634
LK G +P++V G+T LD++R+ TF+ ++
Sbjct: 133 TLKINGRLNPSQVFGITMLDIIRSQTFLNDL 163
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 149 bits (362), Expect = 5e-35
Identities = 74/162 (45%), Positives = 105/162 (64%)
Frame = +2
Query: 146 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHK 325
R K IGQPL+LLL++ P + LAL+D++ + G+A DLSH++ KV G
Sbjct: 21 RTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMK-GIATDLSHISQTGKVIGFT 79
Query: 326 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 505
G +EL +A+ ADVVV+ AG+PR PGM RD L N ++ +A +I+ +P+A +A IT
Sbjct: 80 GEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFIT 139
Query: 506 NPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGE 631
NPVN VP A+EVL G +D R+ G+TTLDVVR+ F+G+
Sbjct: 140 NPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGD 181
>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
Leishmania major
Length = 322
Score = 149 bits (362), Expect = 5e-35
Identities = 83/157 (52%), Positives = 105/157 (66%), Gaps = 8/157 (5%)
Frame = +2
Query: 185 IGQPLALLL-KQNPLVTRLALYDIAPVTPGVAADLSHM-NTPAKVS------GHKGPEEL 340
IGQ L+LLL +Q P + L+L+D+ GVAADLSH+ N +V GHK L
Sbjct: 13 IGQSLSLLLVRQLPYGSTLSLFDVVGAA-GVAADLSHVDNAGVQVKFAEGKIGHKRDPAL 71
Query: 341 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 520
+ K DV V+ AGVPRKPGMTRDDLF NA I+ D+ L+ A ++PKA+ I+TNPVNS
Sbjct: 72 AELAKGVDVFVMVAGVPRKPGMTRDDLFKINAGIILDLVLTCASSSPKAVFCIVTNPVNS 131
Query: 521 TVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGE 631
TV IA+E LK GVYD NR+LGV+ LD +RA F+ E
Sbjct: 132 TVAIAAEALKSLGVYDRNRLLGVSLLDGLRATCFINE 168
>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
Saccharomycetaceae|Rep: Malate dehydrogenase,
cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
Length = 377
Score = 132 bits (318), Expect = 1e-29
Identities = 83/172 (48%), Positives = 106/172 (61%), Gaps = 21/172 (12%)
Frame = +2
Query: 185 IGQPLALLLK---------QNPLVTR--LALYDI-APVTPGVAADLSHMNTPAKVSGHKG 328
IGQ L+LLLK N VT LALYD+ GV ADLSH++TP VS H
Sbjct: 25 IGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSHIDTPISVSSHSP 84
Query: 329 PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ--NAPKAIVAII 502
+ + +A +VVIPAGVPRKPGMTRDDLFN NA I+ + SIA+ + K V +I
Sbjct: 85 AGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKVFVLVI 144
Query: 503 TNPVNSTVPI-ASEVLK------KAGVYDPNRVLGVTTLDVVRAATFVGEIN 637
+NPVNS VP+ S +LK +G+ R++GVT LD+VRA+TF+ EIN
Sbjct: 145 SNPVNSLVPVMVSNILKNHPQSRNSGI--ERRIMGVTKLDIVRASTFLREIN 194
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 131 bits (317), Expect = 1e-29
Identities = 73/167 (43%), Positives = 99/167 (59%), Gaps = 9/167 (5%)
Frame = +2
Query: 152 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTP--GVAADLSHMNTPAKVSGH 322
FK IGQPL LL+ +P V L ++D+ + P GVA DL H+ A V G+
Sbjct: 81 FKVCVCGGAGGIGQPLCLLMAMDPNVKELCVFDLNVAMVPAQGVATDLGHLEKKAAVKGY 140
Query: 323 ------KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK 484
K + L + +V+IPAG+PRKPG TRDDLF NA I + I + A+ P
Sbjct: 141 VMEVGQKPVDNLEECLTGCHLVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAKYCPD 200
Query: 485 AIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFV 625
A++ +I NPVNS VP +E+ KK G+ DP +++G+TTLDVVRA FV
Sbjct: 201 AMLGMIVNPVNSVVPAMAELYKKKGL-DPMKIVGITTLDVVRANKFV 246
>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 405
Score = 130 bits (314), Expect = 3e-29
Identities = 64/99 (64%), Positives = 76/99 (76%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 364
IGQPL+LL+K +PLV+ L LYDIA V GV ADL H NTPAKV+G G EEL+ + D
Sbjct: 89 IGQPLSLLVKMSPLVSALHLYDIANVD-GVTADLGHCNTPAKVAGFTGKEELAGCLAGVD 147
Query: 365 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAP 481
VVVIPAGVPRKPGMTRDDLF NA IVR++ ++A +AP
Sbjct: 148 VVVIPAGVPRKPGMTRDDLFGINAGIVRELVEAVADHAP 186
Score = 36.7 bits (81), Expect = 0.52
Identities = 22/53 (41%), Positives = 28/53 (52%)
Frame = +1
Query: 499 HHKPC*LYSAYCL*SAQEGGSVRPEPRARRHHSGRSPRCHLRRRDQWRGPDLR 657
H +P L+ A A+ G VRP RRH +GR R H+RR D+ GP R
Sbjct: 193 HLQPGELHRADRRRGAEAEGRVRPAEAVRRHDAGRRARQHVRRGDE--GPPAR 243
>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Canis
familiaris
Length = 245
Score = 125 bits (301), Expect = 1e-27
Identities = 54/84 (64%), Positives = 69/84 (82%)
Frame = +2
Query: 389 PRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYD 568
PRKPGMTRDDLFNTNAS+V + AQ+ P+A++ +I+NPVNST+PIA+EV KK G YD
Sbjct: 61 PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAMICVISNPVNSTIPIATEVFKKHGAYD 120
Query: 569 PNRVLGVTTLDVVRAATFVGEING 640
PN++ VTTLD+VRA TF+ E+NG
Sbjct: 121 PNKIFRVTTLDIVRANTFIAELNG 144
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 125 bits (301), Expect = 1e-27
Identities = 82/170 (48%), Positives = 101/170 (59%), Gaps = 23/170 (13%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVT--------RLALYDIAP-VTPGVAADLSHMNTPAKVSGH----- 322
IGQPL+LLLK LALYD+A GVAADLSH+NTP +VS H
Sbjct: 35 IGQPLSLLLKTQLAQVLGDANASLELALYDVAADALAGVAADLSHVNTPVEVSHHVPSSR 94
Query: 323 KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ--NAPKAIVA 496
+ E L A+ A VVVIPAGVPRKPGMTRDDL N NA I++ +A IA + K V
Sbjct: 95 EDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKGIAGACDLEKVFVL 154
Query: 497 IITNPVNSTVPI-ASEVLKKAGVYD------PNRVLGVTTLDVVRAATFV 625
+I+NPVNS VP+ ++++ A RV GVT LD+VRA+ FV
Sbjct: 155 VISNPVNSLVPVMVRQLIRHAEAKQAPHAGVERRVFGVTQLDMVRASAFV 204
>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 387
Score = 122 bits (293), Expect = 1e-26
Identities = 74/153 (48%), Positives = 97/153 (63%), Gaps = 6/153 (3%)
Frame = +2
Query: 185 IGQPLALLLK-----QNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSA 346
IGQ L+LLL+ N LAL+D+ V GV ADLSH+NT K+S H + L
Sbjct: 52 IGQSLSLLLRTSLQNNNDNQLHLALFDVNMKVLNGVHADLSHVNTNMKLSLH---DNLRD 108
Query: 347 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 526
++ D+++V+IPAGVPRKPGMTRDDLFN NA I++ IA + V +I+NPVNS +
Sbjct: 109 SLVDSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIAQELNTIDSTPFVLLISNPVNSLL 168
Query: 527 PIASEVLKKAGVYDPNRVLGVTTLDVVRAATFV 625
P+ VL VY R G+T LD+VRA+TFV
Sbjct: 169 PVLQSVLN--DVY-LGRCFGITELDLVRASTFV 198
>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7998-PA - Tribolium castaneum
Length = 376
Score = 118 bits (285), Expect = 1e-25
Identities = 59/153 (38%), Positives = 98/153 (64%)
Frame = +2
Query: 188 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADV 367
G+ ++L+LKQ+P + L LYD + G A DL++++T +V+ G +++ A+ +++
Sbjct: 41 GKSVSLMLKQSPFIDELCLYDTQSLE-GFANDLNYVDTKCRVTSFFGNKDIQKALTKSNI 99
Query: 368 VVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVL 547
+V+ + LF+ NA IV+D+A SIA+ +PK+ VAI P+NS VP+ SE++
Sbjct: 100 IVVLSCCHAAEPTNYASLFDRNAPIVKDLATSIAKFSPKSTVAIGVEPINSVVPMFSEIM 159
Query: 548 KKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
KK G Y+P + G+TT+DVVR FV EI G++
Sbjct: 160 KKYGHYNPYSIFGITTVDVVRTNKFVAEILGLE 192
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 118 bits (285), Expect = 1e-25
Identities = 72/171 (42%), Positives = 103/171 (60%), Gaps = 19/171 (11%)
Frame = +2
Query: 185 IGQPLALLLKQN-----PLVT----RLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPE 334
IGQ L+LLLK N P T RL+LYD+ G AADLSH++TP + H +
Sbjct: 58 IGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAADLSHIDTPITTTAHYPDD 117
Query: 335 E---LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ--NAPKAIVAI 499
+ + +A VV+IPAGVPRKPGM+RDDL NA I++ + IA+ + K V +
Sbjct: 118 SNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKSLGEDIAKYCDLNKVHVLV 177
Query: 500 ITNPVNSTVPIASEVLKKAGVYD----PNRVLGVTTLDVVRAATFVGEING 640
I+NP+NS VP+ + L ++ +RV G+T LD+VR++TFV ++NG
Sbjct: 178 ISNPINSLVPLLTNTLIRSDANGNSNIESRVYGITQLDLVRSSTFVQQLNG 228
>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Plicopurpura patula
Length = 229
Score = 113 bits (273), Expect = 3e-24
Identities = 55/77 (71%), Positives = 62/77 (80%)
Frame = +2
Query: 416 DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTT 595
DLFNTNA IVRD+ IA+ P A++ IITNPVNSTVPIASEVLKK GVYDP RV GVTT
Sbjct: 1 DLFNTNAGIVRDLTDRIAKVCPTAMLGIITNPVNSTVPIASEVLKKRGVYDPKRVFGVTT 60
Query: 596 LDVVRAATFVGEINGVD 646
LDVVR+ TF+ E G+D
Sbjct: 61 LDVVRSNTFIAEAKGLD 77
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 105 bits (253), Expect = 8e-22
Identities = 53/154 (34%), Positives = 97/154 (62%), Gaps = 1/154 (0%)
Frame = +2
Query: 188 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEE-LSAAIKDAD 364
G L+L LKQ+PL+ LA++D T G+A DL++++T KVS PE+ L ++ A
Sbjct: 13 GNCLSLFLKQSPLIDELAIFDNNSSTYGLALDLNYIDTKCKVSTCNHPEKCLEETLQGAK 72
Query: 365 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 544
+V+I V + +++ +NA I+ D+ +I + +P+A++AI+ NP+NS +P+ E+
Sbjct: 73 IVMI---VTDRTSNESNEVLKSNAIILSDLLPNIIKFSPQAMLAIVMNPINSLIPLTMEM 129
Query: 545 LKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
KKAG+Y+ NR+ GV + ++A +F ++ ++
Sbjct: 130 YKKAGIYEYNRIFGVMNFECLKANSFTADLINIE 163
>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Tribolium
castaneum
Length = 374
Score = 102 bits (245), Expect = 7e-21
Identities = 58/149 (38%), Positives = 85/149 (57%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 364
+G LALLLKQN + L L+D T A DL+ ++T K+ + L AI A
Sbjct: 40 VGSNLALLLKQNLDIYELRLFDEENNTNAFACDLNEIDTRTKLKSFSC-KSLKNAIVGAH 98
Query: 365 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 544
VV+ G KPG ++ +LF+ N VR++A+ +A+ P+AI I PV + VP+ SE
Sbjct: 99 VVISTGGCQEKPGSSQRELFDKNLDNVRNVAMFLAEFNPEAIYCIAKPPVEALVPMVSEE 158
Query: 545 LKKAGVYDPNRVLGVTTLDVVRAATFVGE 631
KKA YDP +++GV T+ + A TF+ E
Sbjct: 159 YKKAETYDPRKIIGVATVASMIANTFIAE 187
>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
Length = 477
Score = 101 bits (242), Expect = 2e-20
Identities = 48/81 (59%), Positives = 60/81 (74%)
Frame = +2
Query: 404 MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVL 583
MTRDDLF N IV+ + +IA N P A++ +I+NPVNSTVPIA+EVLK G YDP ++
Sbjct: 1 MTRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVNSTVPIAAEVLKAKGKYDPKKLF 60
Query: 584 GVTTLDVVRAATFVGEINGVD 646
GVTTLDVVRA TF E G++
Sbjct: 61 GVTTLDVVRAKTFYAEKAGLE 81
>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
Trypanosomatidae|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 342
Score = 91.1 bits (216), Expect = 2e-17
Identities = 56/170 (32%), Positives = 88/170 (51%), Gaps = 5/170 (2%)
Frame = +2
Query: 131 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP----GVAADLSHMN 298
S T+ + K +GQPL+LLLK NP V L + A G+AADLSH++
Sbjct: 8 SLTALKKGKVVLFGCSNAVGQPLSLLLKMNPHVEELVCCNTAADDDVPGSGIAADLSHID 67
Query: 299 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP-GMTRDDLFNTNASIVRDIALSIAQN 475
T KV + A ++DA ++++ G RD A +R + ++A +
Sbjct: 68 TLPKVHYATDEGQWPALLRDAQLILVCFGSSFDLLREDRDIALKAAAPTMRRVMAAVASS 127
Query: 476 APKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFV 625
VA++++PVN+ P +E+LK +G +DP ++ GVTTLDV+R V
Sbjct: 128 DTTGNVAVVSSPVNALTPFCAELLKASGKFDPRKLFGVTTLDVIRTRKLV 177
>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Tribolium
castaneum
Length = 349
Score = 89.0 bits (211), Expect = 9e-17
Identities = 51/176 (28%), Positives = 90/176 (51%)
Frame = +2
Query: 119 AKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMN 298
+++F + Q++ + +GQ LA L+KQNP ++ L L + V +A D +H +
Sbjct: 11 SRHFCSKPQKHVQVCILGADTLLGQSLAFLIKQNPAISGLHLQGTSKVE-SMALDFNHFD 69
Query: 299 TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA 478
T +V + + +S ++K AD+VV+ M+ L V +A + A+ A
Sbjct: 70 TRCRVHSYYDMDSVSKSVKCADIVVMLGLNTSTSKMSIPKLVMAEGVRVAKLAETCAKYA 129
Query: 479 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
PKA++ + P++ T+PI +EV K++ Y P R+LG L V+A G +D
Sbjct: 130 PKAVIVVAVTPISVTLPIVAEVYKQSDWYHPGRLLGSAALAEVKANAIAGHYQTLD 185
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 83.8 bits (198), Expect = 3e-15
Identities = 59/152 (38%), Positives = 82/152 (53%), Gaps = 3/152 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGH-KGPEELSAAIKD 358
IG LALL L + ++D+ P G DL + + V +G + S +KD
Sbjct: 168 IGATLALLSAVKELGD-VVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGSNDYSV-LKD 225
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
ADV+++ AGVPRKPGM+RDDL NA I+ + +I Q P A V ITNP++ V I
Sbjct: 226 ADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVMVYILR 285
Query: 539 EVLKKAGVYDPNRVLGVT-TLDVVRAATFVGE 631
E K G+ P++V G+ LD R TF+ E
Sbjct: 286 E---KCGL-PPHKVCGMAGVLDSARLRTFLSE 313
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 81.4 bits (192), Expect = 2e-14
Identities = 59/160 (36%), Positives = 82/160 (51%), Gaps = 8/160 (5%)
Frame = +2
Query: 188 GQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNT----PAKVSGHK-GPEELS-A 346
G A L + + + L DI P G+A D++ KV G P+
Sbjct: 24 GSTTAQRLAEYDIFETVVLTDIIEGRPEGLALDINQSRPIEGFETKVIGKTTSPDGAGYE 83
Query: 347 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 526
I DA +V+I AGVPRKPGM+R DL TNA IVR +A +IA+ AP A+V +++NP++
Sbjct: 84 VIADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDEMT 143
Query: 527 PIASEVLKKAGVYDPNRVLG-VTTLDVVRAATFVGEINGV 643
+ V + NRV+G LD R + FV E GV
Sbjct: 144 ALTQLVTG----FPKNRVMGQAGMLDTARFSHFVAEELGV 179
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 79.0 bits (186), Expect = 1e-13
Identities = 59/157 (37%), Positives = 83/157 (52%), Gaps = 9/157 (5%)
Frame = +2
Query: 188 GQPLALLLKQNPLVTRLAL----YDIAPVTPGVAADLSHMNTPAK----VSGHKGPEELS 343
G +A +L N + L YD+A G A D+S A+ V KGPE++
Sbjct: 16 GSTVAFILAMNGSCHHVMLRGRNYDVAK---GKALDMSQAANAARQHTIVKAAKGPEDME 72
Query: 344 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 523
+ DVV+I AG PR PGM+RDDL NA IV+ + I + AP AIV +++NP++
Sbjct: 73 GS----DVVIITAGAPRTPGMSRDDLLFKNADIVKCYSREIKEYAPDAIVIVVSNPLDVM 128
Query: 524 VPIASEVLKKAGVYDPNRVLGVT-TLDVVRAATFVGE 631
+A LK+ G + RVLG+ LD R A F+ E
Sbjct: 129 TYVA---LKETG-FPRQRVLGMAGILDAARMAHFIYE 161
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 78.2 bits (184), Expect = 2e-13
Identities = 51/156 (32%), Positives = 86/156 (55%), Gaps = 3/156 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVS-GHKGPEELSAAIKD 358
+G A+++ L ++ L DI P G A D++HM++ + + G E I+
Sbjct: 10 VGTAAAVIMGLMKLDNKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGSNEYKD-IEG 68
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
+D++++ AG+PRKPGMTR+ L NA IV +I I + AP +IV + TNP+++ +
Sbjct: 69 SDLIIVTAGLPRKPGMTREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPLDA----MT 124
Query: 539 EVLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGV 643
V+ KA + RV+G + LD R A + + G+
Sbjct: 125 YVMWKATGFPRERVIGFSGVLDAGRLAFYAAKKLGI 160
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 78.2 bits (184), Expect = 2e-13
Identities = 48/119 (40%), Positives = 71/119 (59%), Gaps = 3/119 (2%)
Frame = +2
Query: 284 LSHMNTPAKVSGHK-GPE-ELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 457
L+ M+ A+V G+ PE E ++ +D+VVI AG PR+PGM+R+DL N I+ IA
Sbjct: 59 LAAMDIDARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIA 118
Query: 458 LSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVT-TLDVVRAATFVGE 631
I + AP AIV ++TNPV+ +A ++L + NRV+G+ LD R TF+ E
Sbjct: 119 DRIKRYAPDAIVIVVTNPVDVMTYVAYKLLN----FPKNRVMGMAGVLDSARFKTFISE 173
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 77.4 bits (182), Expect = 3e-13
Identities = 55/159 (34%), Positives = 83/159 (52%), Gaps = 6/159 (3%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH----MNTPAKVSGHKGPEELSAA 349
+G+ A L +N L L L D V G A D+ + A+V+G E
Sbjct: 14 VGEATAQFLVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGSTNYE----L 69
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
I D+D+VVI AG PRKPGM+R D+ ++N I+ DI ++ + AP+++V I+TNPV+
Sbjct: 70 IADSDLVVITAGKPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVD---V 126
Query: 530 IASEVLKKAGVYDPNRVLG-VTTLDVVRAATFVGEINGV 643
+ + G +D RV G LD R A+F+ G+
Sbjct: 127 LTYHAWRHCG-WDRARVFGQAGVLDSARMASFIAGETGL 164
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 77.0 bits (181), Expect = 4e-13
Identities = 54/151 (35%), Positives = 75/151 (49%), Gaps = 2/151 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
IG LA L+ L + L+DIA TP G A D++ + A I A
Sbjct: 14 IGGTLAHLVALKELGD-VVLFDIAEGTPEGKALDIAESGPSEGFDAKLKGTQSYADIAGA 72
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
DV ++ AGVPRKPGM+RDDL N +++ + I NAP A V ITNP+++ V
Sbjct: 73 DVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPLDAMV----W 128
Query: 542 VLKKAGVYDPNRVLGVT-TLDVVRAATFVGE 631
L++ N+V G+ LD R F+ E
Sbjct: 129 ALQQFSGLPANKVCGMAGVLDSARFRHFLAE 159
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 76.6 bits (180), Expect = 5e-13
Identities = 41/100 (41%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Frame = +2
Query: 236 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 412
L LYD+ P P G A DL H +T V+ + IKDAD++VI AGV RK GMTR
Sbjct: 28 LILYDVVPGIPQGKALDLKHFSTILGVNRNILGTNQIEDIKDADIIVITAGVQRKEGMTR 87
Query: 413 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
+DL N I++ +A S+ + KA V ++NP++ V +
Sbjct: 88 EDLIGVNGKIMKSVAESVKLHCSKAFVICVSNPLDIMVNV 127
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 76.2 bits (179), Expect = 7e-13
Identities = 51/152 (33%), Positives = 75/152 (49%), Gaps = 2/152 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A + P V R+ L D P ++ GV D+ H + S + + +++A
Sbjct: 16 VGATFAYTMAIVPGVARMVLVDAVPGLSKGVMEDIKHAAAVFRRSIQVEAYDDVSKVENA 75
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
D +VI AG PRK M+R DL NA I+RDI + P A +ITNPV+ I S+
Sbjct: 76 DAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDVMTMILSD 135
Query: 542 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEI 634
V+ G V+G T+LD R + V E+
Sbjct: 136 VIGNKGT-----VIGTGTSLDTYRFRSAVSEL 162
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 76.2 bits (179), Expect = 7e-13
Identities = 51/151 (33%), Positives = 80/151 (52%), Gaps = 2/151 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A L + L D+ G A DL H TP + + A +K +
Sbjct: 11 VGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIH-GTPFTRRANIYAGDY-ADLKGS 68
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
DVV++ AGVP+KPG TR L NA ++++IA ++++ AP +IV ++TNPV+ +
Sbjct: 69 DVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVD---VLTYF 125
Query: 542 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
LK++G+ DP +V G T LD R T + +
Sbjct: 126 FLKESGM-DPRKVFGSGTVLDTARLRTLIAQ 155
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 75.8 bits (178), Expect = 9e-13
Identities = 48/134 (35%), Positives = 71/134 (52%), Gaps = 2/134 (1%)
Frame = +2
Query: 236 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 412
+ L+DIA TP G D++ + AAI+ ADVV++ AGVPRKPGM+R
Sbjct: 30 VVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTGANDYAAIEGADVVIVTAGVPRKPGMSR 89
Query: 413 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVT 592
DDL N ++ + I + AP+A V ITNP+++ V L+K ++V+G+
Sbjct: 90 DDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAMV----WALQKFSGLPAHKVVGMA 145
Query: 593 -TLDVVRAATFVGE 631
LD R F+ E
Sbjct: 146 GVLDSARFRYFLSE 159
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 74.5 bits (175), Expect = 2e-12
Identities = 54/158 (34%), Positives = 88/158 (55%), Gaps = 6/158 (3%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHK----GPEELSAA 349
+G A +L N + + + D+ V+ G A D+ M T A++ G G A
Sbjct: 12 VGATCANVLAFNEVADEVVMLDVKEGVSEGKAMDM--MQT-AQLLGFDTTIVGCTNDYAQ 68
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
++DVVVI +G+PRKPGMTR++L NA IV+ +A ++ + +P AI+ +I+NP+++
Sbjct: 69 TANSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMDTMTY 128
Query: 530 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEING 640
+A LK G+ NRV+G+ LD R F+ + G
Sbjct: 129 LA---LKSLGL-PKNRVIGMGGALDSSRFKYFLSQALG 162
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 74.1 bits (174), Expect = 3e-12
Identities = 50/155 (32%), Positives = 81/155 (52%), Gaps = 3/155 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGH-KGPEELSAAIKD 358
+G A+ L + + L DI P G A D++HM + +G + S ++
Sbjct: 10 VGGDAAMFCALRRLDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGSNDYSD-MEG 68
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
+D+VV+ AG RKPGMTR DL NA IV+ + + ++A +++ +TNP++ PI
Sbjct: 69 SDIVVVVAGAGRKPGMTRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPLD---PITY 125
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEING 640
K +G ++ NRV G+ LD+ R F+ E G
Sbjct: 126 IAYKTSG-FEKNRVFGMGGMLDLSRFRQFIHEATG 159
>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to mitochondrial malate dehydrogenase
- Nasonia vitripennis
Length = 299
Score = 73.7 bits (173), Expect = 4e-12
Identities = 39/145 (26%), Positives = 73/145 (50%), Gaps = 1/145 (0%)
Frame = +2
Query: 203 LLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPA 382
+LLKQNP + + L D D+ H++T + H + +++ D+V +
Sbjct: 1 MLLKQNPAIKEIRLIDTDNSLMSPVCDMRHIDTSTTIR-HFRKNSILDGLRNTDIVALMD 59
Query: 383 GVPRKPGMTRDDL-FNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAG 559
G + F +++ V+ +A + PKA+VA+ T+PV +T+P+ SE+ K +G
Sbjct: 60 ETDFMMGNKGPFMQFVNSSNYVKSVAECMINVCPKALVAVFTHPVTATLPLVSEIYKYSG 119
Query: 560 VYDPNRVLGVTTLDVVRAATFVGEI 634
+DPNR+ G L+ +R + +
Sbjct: 120 DWDPNRIFGSAALESMRISAMTATL 144
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 73.7 bits (173), Expect = 4e-12
Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 2/150 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G AL L ++ L + +AL D+ P + G+A D+ H S + A+ A
Sbjct: 134 VGAMTALRLAESDLFSEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSGSDDLVALAGA 193
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
+ +VI AG PR+PGM+R DL NA I+ + I +AP + + I++NP+ +A++
Sbjct: 194 EYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNPLEEMTHLAAQ 253
Query: 542 VLKKAGVYDPNRVLGVT-TLDVVRAATFVG 628
+ G + RVLG+ LD R VG
Sbjct: 254 ---QTG-FPEERVLGMAGVLDSARFCALVG 279
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 73.3 bits (172), Expect = 5e-12
Identities = 50/154 (32%), Positives = 81/154 (52%), Gaps = 2/154 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G AL L ++ L D+A P G A D++HM + + +K +
Sbjct: 10 VGGDAALFSALKRLDDQILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGSNNFEDMKGS 69
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
++VV+ AG RKPGMTR DL NASIV+ + ++ + A +++ +TNP++ P+A
Sbjct: 70 NIVVVVAGSGRKPGMTRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPLD---PMAYI 126
Query: 542 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEING 640
K +G +D +RV G+ LD+ R F+ E G
Sbjct: 127 TYKVSG-FDRSRVFGMGGMLDLSRFRQFIHEATG 159
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 73.3 bits (172), Expect = 5e-12
Identities = 44/116 (37%), Positives = 68/116 (58%), Gaps = 5/116 (4%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAA---- 349
+G A N V +AL DIA + G A DL+H A K P+ + A
Sbjct: 11 VGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAH----AAAGIDKYPKIVGGADYSL 66
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 517
+K ++++V+ AG+ RKPGMTR DL + NA I++DIA I +NAP++ + ++TNP++
Sbjct: 67 LKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMD 122
>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000020184 - Nasonia
vitripennis
Length = 352
Score = 72.9 bits (171), Expect = 6e-12
Identities = 51/169 (30%), Positives = 83/169 (49%), Gaps = 2/169 (1%)
Frame = +2
Query: 131 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAK 310
++++ RN K G+ LAL LKQ+ L+ LA+YD P T G+ +LSHM++ +
Sbjct: 29 TSSNSRNLKVAIVGATGQTGRSLALCLKQSALIDELAVYDSHP-TRGLLLELSHMDSRCR 87
Query: 311 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRD-DLFNTNASIVRDIALSIAQNAPKA 487
SA D+ G + +T D + A + I + PKA
Sbjct: 88 TIVEDEASTTSACNGKRDLERALTGA-KIVAITLDGESIREEAEYLEKILSGLLGCCPKA 146
Query: 488 IVAIITNPVNSTVPIASEVLKKAGVYD-PNRVLGVTTLDVVRAATFVGE 631
+VA+++ VNS VP+ E+ K+AG+++ +R+ GV +L RA E
Sbjct: 147 LVALVSRRVNSLVPMLYELYKRAGLFEASSRIFGVVSLFATRANGLAAE 195
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 72.9 bits (171), Expect = 6e-12
Identities = 34/95 (35%), Positives = 63/95 (66%), Gaps = 1/95 (1%)
Frame = +2
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
++ +DV+V+ AG+ RKPGM+R+DLF+ N I+ D++ +I + +P +I+ +++NP +
Sbjct: 74 MEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSIIVVVSNPAD---- 129
Query: 530 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
I + L+K DP R++G+ +LD R TF+ +
Sbjct: 130 IMAYALQKISGVDPQRIMGLGGSLDSSRFRTFLAK 164
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 72.9 bits (171), Expect = 6e-12
Identities = 40/93 (43%), Positives = 60/93 (64%), Gaps = 1/93 (1%)
Frame = +2
Query: 356 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 535
DADV+V+ AG+PRKPG TR DL NA+I++ +A+ P+AIV ++TNPV+ +A
Sbjct: 73 DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVDVLTYVA 132
Query: 536 SEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
LK +G+ NRV+G+ T LD +R + +
Sbjct: 133 ---LKVSGL-PKNRVIGLGTHLDSMRFKVLIAK 161
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 72.5 bits (170), Expect = 9e-12
Identities = 44/151 (29%), Positives = 81/151 (53%), Gaps = 2/151 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G +A +L + + + D+ T G+A D+ H + K + ++
Sbjct: 9 VGSTVAFILATQGICQEIIIKDLNLDTARGIALDMGHAASATKTHTIVRVANEPSDLRGC 68
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
DVVV AG PR+PGM+RDDL NA ++R + + ++++ +++NP+++ V A
Sbjct: 69 DVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLDAMVYTA-- 126
Query: 542 VLKKAGVYDPNRVLGVT-TLDVVRAATFVGE 631
+K++G+ P +VLG+ LD R A+F+ E
Sbjct: 127 -IKESGL-SPLQVLGMAGILDSARMASFIFE 155
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 71.7 bits (168), Expect = 2e-11
Identities = 52/156 (33%), Positives = 81/156 (51%), Gaps = 3/156 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTP-AKVSGHKGPEELSAAIKD 358
+G +A L + +AL DI V A D++ G ++ A I+
Sbjct: 11 VGASIAYALAMRGVCDEIALVDIFGDVARAKAIDIAQAGCVFCGCLSTAGGDDF-ALIEA 69
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
+D+VV+ AG PRK G TR+DL NA +V+ A +IA+ AP AIV I+TNP++ V
Sbjct: 70 SDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLDVMV---W 126
Query: 539 EVLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGV 643
VL+ +G +D +RV+G+ LD R + + +
Sbjct: 127 TVLRYSG-FDRSRVIGMAGELDSARCRYEIASLKDI 161
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 69.7 bits (163), Expect = 6e-11
Identities = 44/132 (33%), Positives = 69/132 (52%), Gaps = 2/132 (1%)
Frame = +2
Query: 236 LALYDIAPVT-PGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 412
L LYD+ + G++ +L+ P K+ G E++ A + DV +I AGVPRKPGM R
Sbjct: 47 LHLYDLNDMALKGLSMELTDCCLP-KLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQR 105
Query: 413 DDLFNTNASIVRDIALSIAQNAPKAI-VAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV 589
DL N N ++ ++ + K + V ++ NP N+ A + K +G+ P + +
Sbjct: 106 SDLINVNKKVMEMNGKALGTYSNKDVRVVVVANPANTN---AYVICKTSGI-PPEHITAL 161
Query: 590 TTLDVVRAATFV 625
T LD RA FV
Sbjct: 162 TRLDQNRATAFV 173
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 69.7 bits (163), Expect = 6e-11
Identities = 46/149 (30%), Positives = 84/149 (56%), Gaps = 7/149 (4%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALY--DIAPVTPGVAADLSH----MNTPAKVSGHKGPEELSA 346
+G +A L + + L+ DI P GV D+S + P + G EE++
Sbjct: 14 VGSHIAFLGAMRHIAKEILLFSNDI-PRCKGVGLDISQAAAIFDIPILIKGCNSYEEIA- 71
Query: 347 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 526
+++VV+I AG PR P MTR+DL NASI+++I+ ++A+ AP++++ +++NP+++
Sbjct: 72 ---ESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLDAMC 128
Query: 527 PIASEVLKKAGVYDPNRVLGVT-TLDVVR 610
+A + K ++ RV+G+ LD R
Sbjct: 129 LVAKQWSK----FEKERVIGMAGILDSAR 153
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 69.3 bits (162), Expect = 8e-11
Identities = 42/108 (38%), Positives = 66/108 (61%), Gaps = 5/108 (4%)
Frame = +2
Query: 227 VTRLALYDI-APVTPGVAADLSHM----NTPAKVSGHKGPEELSAAIKDADVVVIPAGVP 391
++++AL DI + A DLSH+ N ++SG E L +K++D+VVI AG
Sbjct: 26 ISQIALIDIFGDLAKARALDLSHLASVYNKKTEISG-SSDETL---LKNSDIVVITAGKT 81
Query: 392 RKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 535
R+ G +R DL N NA I+ A ++A+ AP+AI+ +ITNPV++ +A
Sbjct: 82 RQAGQSRADLLNDNAKIISSCAKNVAKYAPEAIIILITNPVDTLAFVA 129
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 68.9 bits (161), Expect = 1e-10
Identities = 49/145 (33%), Positives = 79/145 (54%), Gaps = 3/145 (2%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G +A L NPL + L L + + G A DL+H + E++ + KD+
Sbjct: 11 VGSAIAFALTINPLASELLLLNRSREKAEGDALDLTHAAALVDSNIKISSGEIADS-KDS 69
Query: 362 DVVVIPAGVP-RKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
DV++ A VP R P TR ++ N I+RD +A+ +P AIV +++NPV++ +A
Sbjct: 70 DVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNPVDA---LAY 126
Query: 539 EVLKKAGVYDPNRVLGVTTL-DVVR 610
E ++ G +DP RV+G TL D +R
Sbjct: 127 ETIRLTG-FDPKRVIGTGTLVDSIR 150
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/153 (34%), Positives = 76/153 (49%), Gaps = 6/153 (3%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHK----GPEELSAA 349
+G LA L Q V + L DI P G+ DL V GH G + A
Sbjct: 19 VGSALAQRLIQGN-VADVVLLDIVEGRPQGITLDLLEA---CGVEGHTCRITGTNDY-AQ 73
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
+DV+V+ AG R+PGM+RDDL TN IV ++ ++P+A V ++TNP+++
Sbjct: 74 TAGSDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDA--- 130
Query: 530 IASEVLKKAGVYDPNRVLGVT-TLDVVRAATFV 625
S V +A P RV+G+ LD R TF+
Sbjct: 131 -MSHVAWRASGLVPERVMGMAGVLDAARFETFI 162
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 67.7 bits (158), Expect = 2e-10
Identities = 39/118 (33%), Positives = 66/118 (55%), Gaps = 1/118 (0%)
Frame = +2
Query: 293 MNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 472
M+ V G +E +K +D+VVI AG+PR+ GM+R+DL N I++ +I +
Sbjct: 67 MDIDINVKGISYDKEGFEELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKE 126
Query: 473 NAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGV 643
A +I+ +++NPV++ + +K G ++P RV+G+ LD R FV E G+
Sbjct: 127 YAKDSIIIVVSNPVDT---LTYATIKLTG-FEPRRVIGMAGVLDSARFKNFVKEKIGI 180
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 67.7 bits (158), Expect = 2e-10
Identities = 53/157 (33%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAK-VSGHKGPEELSAAIKD 358
+G A L L + + + DI G A DLSH + K V G E + KD
Sbjct: 16 VGSTTAYALMMEGLASEIVIVDINKEKAKGEAMDLSHGVSFVKPVDIIAGDYEDT---KD 72
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
+D+V+I AG KPG TR DL N N I + I + + +PK+I+ +++NPV+ I +
Sbjct: 73 SDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVD----ILT 128
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
V K + RV+G T LD R +GE +D
Sbjct: 129 YVTYKLSGFPQERVIGSGTVLDTSRFRYLLGEHFKID 165
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 66.5 bits (155), Expect = 6e-10
Identities = 44/112 (39%), Positives = 65/112 (58%), Gaps = 1/112 (0%)
Frame = +2
Query: 278 ADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 457
AD++ + P K+ + G E +A DADVVVI AG+PRKPG TR DL N N +I++ I
Sbjct: 53 ADITPLTNPVKI--YAGTYEDAA---DADVVVITAGIPRKPGETRLDLVNKNTTILKSII 107
Query: 458 LSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVR 610
I ++ + I +NPV+ IA + +G + RV+G T+LD +R
Sbjct: 108 KPIVKSGFTGVFVISSNPVDILTTIAQRI---SG-FPKERVIGTGTSLDSMR 155
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 66.1 bits (154), Expect = 7e-10
Identities = 36/91 (39%), Positives = 58/91 (63%), Gaps = 1/91 (1%)
Frame = +2
Query: 356 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 535
D+DVVVI AG+ RKPGM+R++L + NA IV + + Q++P + + I++NPV+ +A
Sbjct: 71 DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVDIMTYVA 130
Query: 536 SEVLKKAGVYDPNRVLGVT-TLDVVRAATFV 625
K++G + NR++G + LD R FV
Sbjct: 131 ---FKESG-FKRNRIIGQSGVLDSARFRYFV 157
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 66.1 bits (154), Expect = 7e-10
Identities = 53/157 (33%), Positives = 76/157 (48%), Gaps = 3/157 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSH-MNTPAKVSGHKGPEELSAAIKD 358
+G +A L Q L + + L D G A D+SH + + + G E I D
Sbjct: 15 VGSTIAYTLMQKGLFSEMVLLDANKAKAEGEAMDISHGLPFTHAMDIYAGEYE---DIAD 71
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
A VV+I AG +KPG TR DL NA+I+R I I + + I+ I++NPV+ I +
Sbjct: 72 ASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVD----ILT 127
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
EV + + RV+G T LD R + E VD
Sbjct: 128 EVALRESGFPKERVIGSGTVLDTARLKYIISEKLDVD 164
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 66.1 bits (154), Expect = 7e-10
Identities = 36/96 (37%), Positives = 60/96 (62%), Gaps = 1/96 (1%)
Frame = +2
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
I+ + VVV+ AG RKPGM+R+DL + N I+ ++A I ++AP ++V ++TNP++
Sbjct: 72 IEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPMD---- 127
Query: 530 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEI 634
+ + +L K + RV+G+ LD R A FV E+
Sbjct: 128 LMAYILWKVTGFPRERVIGMGGALDSSRFAYFVSEV 163
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 66.1 bits (154), Expect = 7e-10
Identities = 51/127 (40%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Frame = +2
Query: 269 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 448
G A DLSH P S K A KDAD+VVI AG+P+KPG TR DL N I +
Sbjct: 45 GEAMDLSHA-VPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFK 103
Query: 449 DIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFV 625
I I + I I TNPV+ I + V K RV+G TTLD R +
Sbjct: 104 QIVRGIMDSGFDGIFLIATNPVD----ILTYVTWKESGLPKERVIGSGTTLDSARFRYML 159
Query: 626 GEINGVD 646
G+ VD
Sbjct: 160 GDYLDVD 166
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/161 (32%), Positives = 84/161 (52%), Gaps = 8/161 (4%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIA---PVTPGVAADL----SHMNTPAKVSGHKGPEELS 343
+G +A + Q P V + LY G+A D+ + T +V+ P+EL
Sbjct: 13 VGSYVAHAVSQFPHVQEMCLYGRPGNEQYLDGLAHDMMDSFAARGTNTRVTFGTTPKEL- 71
Query: 344 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 523
+ +D++V+ +GVPRK TR DL NA IV+ A + + AP+AI+ ++TNPV+
Sbjct: 72 ---RGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILLVVTNPVDIM 128
Query: 524 VPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGV 643
+A LK +G+ P+RV G+ T LD +R + E V
Sbjct: 129 TTVA---LKYSGMM-PHRVFGLGTHLDSMRLKACLAEFFNV 165
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 65.3 bits (152), Expect = 1e-09
Identities = 41/105 (39%), Positives = 58/105 (55%), Gaps = 3/105 (2%)
Frame = +2
Query: 236 LALYDIAP-VTPGVAADLSHMN--TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 406
++LYDIA ADL+H TPA V G G + A D+DVV I AG +KPG
Sbjct: 38 VSLYDIAKDKVEAEVADLAHGTQFTPASVMG--GADVHDTA--DSDVVFITAGARQKPGQ 93
Query: 407 TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
TR DL NA+I+R + + + +P A+ ++TNP + +A E
Sbjct: 94 TRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNPCDVLTVVAQE 138
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 65.3 bits (152), Expect = 1e-09
Identities = 49/159 (30%), Positives = 76/159 (47%), Gaps = 5/159 (3%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHMNT---PAKVSGHKGPEELSAAI 352
+G LA Q + + L DIA D+ H ++ + G PE
Sbjct: 19 VGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGSDDPE----IC 74
Query: 353 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
+DAD+VVI AG +KPG +R +L +I++ I ++ + AP AI +ITNPV+ I
Sbjct: 75 RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVD----I 130
Query: 533 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
A+ V +K N++ G T LD R + + GV+
Sbjct: 131 ATHVAQKLTGLPENQIFGSGTNLDSARLRFLIAQQTGVN 169
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 64.1 bits (149), Expect = 3e-09
Identities = 47/156 (30%), Positives = 81/156 (51%), Gaps = 2/156 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A LL + ++ L DI + A DL+ M + + +KD
Sbjct: 11 VGASCASLLISRKVCKKVTLIDINKNLAIAKAMDLAQMAAVLNLDIDIFGGDNYELLKDF 70
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
D+VVI AG RK G +RDDL NA IV + +++ APK+I+ ++TNP++ V +A
Sbjct: 71 DIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLDIMVYVA-- 128
Query: 542 VLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGVD 646
K++G + ++V+G+ LD R ++ + G++
Sbjct: 129 -FKESG-FARHKVIGMAGELDSARFRYYMSQKLGLN 162
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 64.1 bits (149), Expect = 3e-09
Identities = 42/126 (33%), Positives = 62/126 (49%), Gaps = 1/126 (0%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPG-VAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+GQ +A N + LYD+ P P ++ H +V I A
Sbjct: 12 VGQTIAYNTIVNGYADEVMLYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDDISGA 71
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
D+VVI AG PRKPGM+R DLF NA I+ D+A + + A+ ++ NPV+ +AS
Sbjct: 72 DIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVANPVDM---MASV 128
Query: 542 VLKKAG 559
+K +G
Sbjct: 129 FMKYSG 134
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 63.7 bits (148), Expect = 4e-09
Identities = 40/99 (40%), Positives = 56/99 (56%), Gaps = 1/99 (1%)
Frame = +2
Query: 353 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
KDAD+VVI AG P KPG +R D +A IV I + ++ I ++TNPV+S I
Sbjct: 74 KDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPVDS---I 130
Query: 533 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
A V + +G+ +VLG T +D R F+G+I VD
Sbjct: 131 AQYVYQLSGL-PKQQVLGTGTAIDSARLKHFIGDILHVD 168
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 63.7 bits (148), Expect = 4e-09
Identities = 37/95 (38%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
Frame = +2
Query: 353 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
KDAD++VI AGVPR PG TR D+ + + VRDI ++ + K I+ ITNP + I
Sbjct: 71 KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPAD----I 126
Query: 533 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEI 634
++ ++KA NRV T+LD R V ++
Sbjct: 127 IADFVRKATGLPKNRVFSTGTSLDTARMRRTVADL 161
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 63.7 bits (148), Expect = 4e-09
Identities = 50/151 (33%), Positives = 75/151 (49%), Gaps = 4/151 (2%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKD-- 358
+G+ AL L + V L L ++ M+ G E SA I++
Sbjct: 12 VGRATALCLAEEEAVKTLHLISRKESLEQNLGEVLDMSDALAAKGVSVKLENSADIENVY 71
Query: 359 -ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 535
+ +VVI AGVPR M RDDL N IV D A IA+ AP +I+ ++TNPV+ +A
Sbjct: 72 GSRIVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVDVMTYVA 131
Query: 536 SEVLKKAGVYDPNRVLGV-TTLDVVRAATFV 625
L+ +G + P+RV G+ LD +R ++
Sbjct: 132 ---LRYSG-FHPSRVFGLGNHLDSLRLKNYM 158
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 63.7 bits (148), Expect = 4e-09
Identities = 50/158 (31%), Positives = 82/158 (51%), Gaps = 4/158 (2%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELS---AAIK 355
+G LA L + + L + + G A D+S A V G + S A
Sbjct: 12 VGATLAQRLIEKDFADVVMLDVVEGIPQGKALDISQS---ASVLGFRHTITGSNDYAQTA 68
Query: 356 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 535
+++VVI AG+ RKPGMTR++L N I+ D+ + + +P+A + +++NPV++ +A
Sbjct: 69 GSEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVDTMTYLA 128
Query: 536 SEVLKKAGVYDPNRVLGVT-TLDVVRAATFVGEINGVD 646
K +G+ RV+G++ LD R ATFV GV+
Sbjct: 129 ---WKLSGL-PRKRVVGLSGVLDGGRLATFVARELGVN 162
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 63.7 bits (148), Expect = 4e-09
Identities = 47/156 (30%), Positives = 74/156 (47%), Gaps = 2/156 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A L Q+ L + + + DI A DL+ K K + A KD+
Sbjct: 17 VGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQGAAFVKSVDIKSGDY--ADTKDS 74
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
D+V+I AGV KPG TR D+ N N I + I + + +P +I+ +++NPV+ I +
Sbjct: 75 DIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPVD----ILTY 130
Query: 542 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
+ K + RV+G T LD R + E +D
Sbjct: 131 ITYKLSGFPKERVIGSGTVLDTSRLKYMLSEHFDID 166
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 62.9 bits (146), Expect = 7e-09
Identities = 53/160 (33%), Positives = 81/160 (50%), Gaps = 11/160 (6%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPA----KVSGHKGPEELSAA 349
IG +A L+ Q L + L+DI P G A D SH N A KVSG ++L+ A
Sbjct: 15 IGGVMATLIVQKNLGD-VVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLAGA 73
Query: 350 IKDADVVVIPAGVPRKPGMT-----RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPV 514
DVV++ AG + PG + RDDL N I+ +I I +N P A + ++TNPV
Sbjct: 74 ----DVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPV 129
Query: 515 NSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
+ V + + +GV N+++G+ LD R ++ +
Sbjct: 130 DVMVQLLHQ---HSGV-PKNKIIGLGGVLDTSRLKYYISQ 165
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 62.9 bits (146), Expect = 7e-09
Identities = 45/144 (31%), Positives = 67/144 (46%), Gaps = 2/144 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A L QN + L + D+ G DL + + E A +DA
Sbjct: 16 VGSSFAFSLVQNCALDELVIVDLVKTHAEGDVKDLEDVAAFTNATNIHTGEYADA--RDA 73
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
D+VVI AGVPRKPG +R DL N N I+ I + + I +NPV+ I +
Sbjct: 74 DIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVISSNPVD----ILTS 129
Query: 542 VLKKAGVYDPNRVLGV-TTLDVVR 610
+ ++ + +RV+G T+LD R
Sbjct: 130 MTQRLSGFPRHRVIGTGTSLDTAR 153
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
Bacteria|Rep: L-lactate dehydrogenase - Treponema
denticola
Length = 315
Score = 62.5 bits (145), Expect = 9e-09
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH-MNTPAKVSGHKGPEELSAAIKD 358
+G A L Q+ +A+ D+ G A DL + +V H G + A D
Sbjct: 16 VGSTFAYALAQSGYADEIAITDMNKNFAEGQALDLVQGLPFLPQVDIHAGDKTDYA---D 72
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
+D+VV+ AG ++ G TR DL NASI+ IA IA++ ++ I++NPV+ I +
Sbjct: 73 SDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVMLIVSNPVD----ILT 128
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
KA ++ RV+G T LD R + + GVD
Sbjct: 129 RAALKASGWERGRVIGSGTVLDTARFRYTLSKECGVD 165
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 62.5 bits (145), Expect = 9e-09
Identities = 58/185 (31%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Frame = +2
Query: 116 GAKNFSTTSQRN--FKXXXXXXXXX--IGQPLALLLKQNPLVTRLALYDI-APVTPGVAA 280
G+K FS S R+ FK +G A L + L + + D+ G A
Sbjct: 4 GSKVFSNDSVRSSSFKSIKIVIVGAGNVGSTTAFTLLLSGLAAEIVIIDLNKKKAEGEAM 63
Query: 281 DLSHMNTPAKVSGHKGPEELS--AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDI 454
DL+H A H+ L KDA VVI AG +KPG TR DL N SI ++I
Sbjct: 64 DLNH----AAPLSHETRVYLGDYKDCKDATAVVITAGKNQKPGETRMDLLKANISIFKEI 119
Query: 455 ALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
+ + AI+ + TNPV+ + LK G + RV+G T +D R +G+
Sbjct: 120 LREVTKYTKDAILLVATNPVD---VLTYATLKLTG-FPAERVIGSGTIIDTARFQYLIGK 175
Query: 632 INGVD 646
+ G+D
Sbjct: 176 LYGLD 180
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 60.5 bits (140), Expect = 4e-08
Identities = 40/97 (41%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
Frame = +2
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
A +VV+ AG + PG +R DL NA I RDI ++ Q A + + TNPV+ +A
Sbjct: 69 ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVDVLTHVAR 128
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
V GV P RV+G T LD R V EI GVD
Sbjct: 129 TV---TGV-APGRVIGSGTVLDSARFRGHVAEILGVD 161
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 60.1 bits (139), Expect = 5e-08
Identities = 34/88 (38%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Frame = +2
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
+KDAD +VI AG P+KPG TR +L N I+R+IAL + ++ I I+ NPV+
Sbjct: 69 LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVD---- 124
Query: 530 IASEVLKKAGVYDPNRVLGV-TTLDVVR 610
I + + A + +V+G T LD R
Sbjct: 125 IITRAYRDASGFSDQKVIGSGTVLDTAR 152
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 59.7 bits (138), Expect = 6e-08
Identities = 38/104 (36%), Positives = 57/104 (54%), Gaps = 3/104 (2%)
Frame = +2
Query: 344 AAIKDADVVVIPAGVPRK-PGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 520
AA+ +A ++V+ AG ++ P TR L NA I R+I + + ++AP AI+ + TNPV+
Sbjct: 67 AALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVDV 126
Query: 521 TVPIASEVLKKAGVYDPN-RVLGV-TTLDVVRAATFVGEINGVD 646
I E+ + PN R+LG T LD R +G GVD
Sbjct: 127 LTYICQELSSR-----PNRRILGTGTLLDTARFRALLGRHYGVD 165
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 59.3 bits (137), Expect = 9e-08
Identities = 38/100 (38%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +2
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
+ DAD+VVI AG K G TRDDL N+ I DIA I AP AI+ ++TNP +
Sbjct: 68 LTDADIVVITAGAQIKEGQTRDDLAEINSRITVDIAQKIETVAPNAILLVVTNPCD---- 123
Query: 530 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
IA+ + + + +RV+ +D R V E VD
Sbjct: 124 IATYFITQNTGFPADRVISAGCIIDTARLMKLVSEKVDVD 163
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 59.3 bits (137), Expect = 9e-08
Identities = 44/157 (28%), Positives = 76/157 (48%), Gaps = 3/157 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSH-MNTPAKVSGHKGPEELSAAIKD 358
+G A + L L D+ G A D++H + ++S + G + +KD
Sbjct: 18 VGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAGDY---SDVKD 74
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
DV+V+ AG RKPG TR DL N I +++ +I + ++ +++NPV+ I +
Sbjct: 75 CDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPVD----IIT 130
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
+++K +V+G T LD +R + E GVD
Sbjct: 131 YMIQKWSGLPVGKVIGSGTVLDSIRFRYLLSEKLGVD 167
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 59.3 bits (137), Expect = 9e-08
Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 11/160 (6%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPA----KVSGHKGPEELSAA 349
IG +A L+ Q L + ++D+ P G A D SH N A KV+G ++L
Sbjct: 8 IGGVMATLIVQKNLGD-VVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDL--- 63
Query: 350 IKDADVVVIPAGVPRKPGMT-----RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPV 514
K ADVV++ AG + PG + RDDL N I+ +I I P A + ++TNPV
Sbjct: 64 -KGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPV 122
Query: 515 NSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
+ V + + + +GV N+++G+ LD R ++ +
Sbjct: 123 DVMVQL---LFEHSGV-PKNKIIGLGGVLDTSRLKYYISQ 158
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 58.4 bits (135), Expect = 1e-07
Identities = 36/93 (38%), Positives = 54/93 (58%), Gaps = 1/93 (1%)
Frame = +2
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
+ +D+VVI AG PR PG R DL NA I+ +A +I AP + ++TNPV+
Sbjct: 71 VAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMVTNPVDVMTC 130
Query: 530 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFV 625
+A LK +G+ PN+V G+ T LD +R + +
Sbjct: 131 VA---LKYSGL-KPNQVFGLGTHLDSMRLKSLI 159
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 58.4 bits (135), Expect = 1e-07
Identities = 53/174 (30%), Positives = 75/174 (43%), Gaps = 4/174 (2%)
Frame = +2
Query: 137 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPV---TPGVAADLSHMNTPA 307
TS + K +G A L + L + +I + G A DLSH A
Sbjct: 2 TSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLHEKAVGDALDLSH--ALA 59
Query: 308 KVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA 487
S K + DAD+VVI AG P+KPG TR DL N +I + I + ++ K
Sbjct: 60 FTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKG 119
Query: 488 IVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
I + NPV+ + K +G + RV+G T+LD R + E VD
Sbjct: 120 IFLVAANPVD---VLTYSTWKFSG-FPKERVIGSGTSLDSARFRQALAEKLDVD 169
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 58.4 bits (135), Expect = 1e-07
Identities = 40/126 (31%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Frame = +2
Query: 269 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 448
G A D+S +G K A K AD++++ AG P+K G TR ++ N+ I++
Sbjct: 41 GHAMDMSDAIALNSTTGSKIRTGTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMK 100
Query: 449 DIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFV 625
DIAL I ++ +I+NPV+ I + V +K + +V+ T LD R F+
Sbjct: 101 DIALEIKKSGFNGFTIVISNPVD----ILATVFQKVTNFPKEKVMSSGTFLDTSRFRKFL 156
Query: 626 GEINGV 643
E GV
Sbjct: 157 SEKTGV 162
>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
Bacillaceae|Rep: L-lactate dehydrogenase -
Oceanobacillus iheyensis
Length = 321
Score = 57.2 bits (132), Expect = 3e-07
Identities = 51/167 (30%), Positives = 73/167 (43%), Gaps = 2/167 (1%)
Frame = +2
Query: 137 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKV 313
TSQ+ +G A L + LA+ D+ A G DL+H A
Sbjct: 3 TSQQAVNRVVLIGGGSVGVSYAFALMNQGVTEELAIIDLDADKALGDVMDLNHGKAFAPS 62
Query: 314 SGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIV 493
+ E KDAD+V I AG ++ G TR DL N I ++I + + I
Sbjct: 63 LTNVWLGEYGDC-KDADIVCICAGANQQSGETRLDLVEKNMKIFKEIVTDVMNSGFNGIF 121
Query: 494 AIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
I TNPV+ + V+ +G+ P+RV+G TTLD R +GE
Sbjct: 122 LIATNPVDI---LTQAVISFSGL-PPHRVIGSGTTLDTARLRYELGE 164
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/94 (36%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
Frame = +2
Query: 353 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
KDAD++VI AG P++PG TR +L N+ I++ IA +I + + I +NP + +
Sbjct: 72 KDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNPCD----V 127
Query: 533 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
+ V ++ YD + V+G TTLD R V E
Sbjct: 128 LTTVYQQVTGYDEHSVVGAGTTLDSARLRRLVAE 161
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 56.8 bits (131), Expect = 5e-07
Identities = 33/88 (37%), Positives = 53/88 (60%), Gaps = 1/88 (1%)
Frame = +2
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
+KD DVVVI AG P+KPG TR ++ NA I+ +IA +I ++ K + ++ NPV+
Sbjct: 71 LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVD---- 126
Query: 530 IASEVLKKAGVYDPNRVLGV-TTLDVVR 610
+ + + + +D NRV+ T+LD R
Sbjct: 127 VMTFIYQHETGFDKNRVISSGTSLDSAR 154
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 56.4 bits (130), Expect = 6e-07
Identities = 46/143 (32%), Positives = 69/143 (48%), Gaps = 7/143 (4%)
Frame = +2
Query: 236 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG--- 403
+ L+D+ P P G A DL H A A+++ ADVV+I AG+ + G
Sbjct: 36 VVLFDVVPNMPAGKALDLCHTAAVADNGVRVQGANSYASLEGADVVIITAGITKAAGKSD 95
Query: 404 --MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNR 577
+R DL N I+R++ +I Q P A V ITNP++ V +A+ L++A R
Sbjct: 96 QEWSRKDLLPVNVKILREVGAAIKQFCPHAFVINITNPLD--VMVAA--LREAAGLPAAR 151
Query: 578 VLGVT-TLDVVRAATFVGEINGV 643
V G+ LD R + + GV
Sbjct: 152 VCGMAGVLDSARFRRLLADRLGV 174
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 56.4 bits (130), Expect = 6e-07
Identities = 49/155 (31%), Positives = 72/155 (46%), Gaps = 6/155 (3%)
Frame = +2
Query: 185 IGQPLALLLK-QNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKD 358
+G A L N LV L + D+ G DL+H K K L KD
Sbjct: 15 VGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLK----KNINVLFGTYKD 70
Query: 359 ---ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
AD+VVI AG+ +KPG TR DL + N+ I +DI ++ + I + +NPV+
Sbjct: 71 CANADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVD---- 126
Query: 530 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
I + V K + ++V+G T LD R F+ +
Sbjct: 127 IMTYVTMKYSKFPIHKVIGTGTILDTSRLRYFLSD 161
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 56.4 bits (130), Expect = 6e-07
Identities = 52/160 (32%), Positives = 75/160 (46%), Gaps = 6/160 (3%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHM----NTPAKVSGHKGPEELSAA 349
+G A + + L L DI G A DLSH NT KV + G E
Sbjct: 16 VGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKV--YAGSYE---D 70
Query: 350 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 529
KD D+V+I AG KPG +R D +A I+ + + ++ I + +NPV+
Sbjct: 71 CKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDI--- 127
Query: 530 IASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
I +V K +G+ NRV+G T+LD R T + E+ VD
Sbjct: 128 ITYQVWKLSGL-PRNRVIGTGTSLDSSRLRTILSEMLHVD 166
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 56.0 bits (129), Expect = 8e-07
Identities = 36/99 (36%), Positives = 57/99 (57%), Gaps = 1/99 (1%)
Frame = +2
Query: 353 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
K AD++VI AG+ +KPG TR L NA I+++I +I + + + +NPV+ +
Sbjct: 70 KYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVD---VL 126
Query: 533 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
A VL+++G+ N+VLG T LD R + +G VD
Sbjct: 127 AELVLQESGL-PRNQVLGSGTALDSARLRSEIGLRYNVD 164
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 56.0 bits (129), Expect = 8e-07
Identities = 36/109 (33%), Positives = 55/109 (50%)
Frame = +2
Query: 320 HKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI 499
H G EL+ DA VV++ AG +KPG +R DL NA I R++ I + AP A++ +
Sbjct: 59 HGGHSELA----DAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLV 114
Query: 500 ITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
+NPV+ +A+++ V T LD R + + GVD
Sbjct: 115 TSNPVDLLTDLATQLAPGQPVIGSG-----TVLDSARFRHLMAQHAGVD 158
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 55.6 bits (128), Expect = 1e-06
Identities = 34/87 (39%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
Frame = +2
Query: 353 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
+DAD+VVI AG +KPG +R DL + NA I++ I +I ++ I+ I +NPV+ +
Sbjct: 72 QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPVD----V 127
Query: 533 ASEVLKKAGVYDPNRVLGV-TTLDVVR 610
+ V +A +RV+G TTLD R
Sbjct: 128 LTYVAWQASGLPVSRVIGTGTTLDTTR 154
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/90 (34%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Frame = +2
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
AD+VVI AG+PRK R L + NA+++ D+ +P I+ ++TNP++ +A
Sbjct: 68 ADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQLAY 127
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFV 625
+V +G+ NRV+G+ T LD R +++
Sbjct: 128 QV---SGL-PANRVIGMGTVLDTARYRSYL 153
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 54.4 bits (125), Expect = 2e-06
Identities = 49/156 (31%), Positives = 68/156 (43%), Gaps = 2/156 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A L Q L + L D G A DL+H P + E A + A
Sbjct: 21 VGASFAFALLQRRLAAEIVLIDANHKKAEGEAMDLNHA-VPFGAATRIWAGEY-ADCRGA 78
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
V VI AG ++PG TR L + N +I + I + ++ P ++ I TNPV+ I S
Sbjct: 79 AVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVD----IISY 134
Query: 542 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
K +RVLG T LD R +G+ VD
Sbjct: 135 ASYKISGLPAHRVLGSGTILDTARFRYLLGQHFSVD 170
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 2/144 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
IG +A L + LYD AP GVA +L H + ++ A+ A
Sbjct: 18 IGSNMAQTALMMKLTPNICLYDPYAPALEGVAEELYHCAFEGVNLTYTS--DIKEALSGA 75
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNPVNSTVPIAS 538
+V G RK GMTR+DL NA I I Q P V ++ NP + T I
Sbjct: 76 KYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVVFNPADITGLI-- 133
Query: 539 EVLKKAGVYDPNRVLGVTTLDVVR 610
VL AG+ P++V + LD R
Sbjct: 134 -VLLYAGL-KPSQVSTLAALDSTR 155
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 54.0 bits (124), Expect = 3e-06
Identities = 45/153 (29%), Positives = 71/153 (46%), Gaps = 5/153 (3%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHMNTPAKVSGH---KGPEELSAAI 352
+G A + + + L D+ A D++H P VS G ++LS A
Sbjct: 2 VGSAAAFACIMRGVASEIVLVDLDTARAQAEAEDIAHA-VPFSVSARIVAGGYDDLSGA- 59
Query: 353 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
DVV++ GV +KPG +R +L + NA + R + + + AP AI+ I +NPV+ I
Sbjct: 60 ---DVVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVD----I 112
Query: 533 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVG 628
+ V + RV+G T LD R +G
Sbjct: 113 MTHVTQALSGLPAGRVIGSGTILDTARFRWLLG 145
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 52.8 bits (121), Expect = 7e-06
Identities = 39/109 (35%), Positives = 58/109 (53%), Gaps = 1/109 (0%)
Frame = +2
Query: 263 TPGVAADLSH-MNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 439
T G AAD +H + + +G E +A +DVVVI AG+PR+PG TR DL NA
Sbjct: 42 TVGQAADTNHGIAYDSNTRVRQGGYEDTAG---SDVVVITAGIPRQPGQTRIDLAGDNAP 98
Query: 440 IVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLG 586
I+ DI S+ ++ I +NPV+ + + L +AG +V+G
Sbjct: 99 IMEDIQSSLDEHNDDYISLTTSNPVD----LLNRHLYEAGDRSREQVIG 143
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 52.4 bits (120), Expect = 1e-05
Identities = 46/158 (29%), Positives = 72/158 (45%), Gaps = 4/158 (2%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGV-AADLSHM--NTPAKVSGHKGPEELSAAIK 355
+G +A + N + L L DI A DL H + +K+ G E
Sbjct: 16 VGAAVAFDMVMNHVCDDLILIDINKEKSWAEATDLQHSLGYSGSKMRVKDGEYE---ECN 72
Query: 356 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 535
DAD+VVI A +P G TR D+ A I+ +I +I ++ I+ +ITNPV+ +
Sbjct: 73 DADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPVD----VM 128
Query: 536 SEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
S + K ++V+G T LD R + ++ VD
Sbjct: 129 SYYVHKLSGLPASKVIGTGTALDSARLKYHLADVMSVD 166
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 52.4 bits (120), Expect = 1e-05
Identities = 46/153 (30%), Positives = 73/153 (47%), Gaps = 4/153 (2%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A L+ + +AL D+ A + G A DL H P+ V+ I D+
Sbjct: 12 VGSCAAFALQCGGIAREIALLDLNADLAGGHALDLLH-GAPS-VADQVITSGGYEHIPDS 69
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK--AIVAIITNPVNSTVPIA 535
DV+ I AG+ RKP +R DL N N + I S+ K AI +++NPV+ +A
Sbjct: 70 DVICITAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSNPVDILTYLA 129
Query: 536 SEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
++ L +RV+G+ T LD +R + +
Sbjct: 130 AQRLN----LPTSRVIGLGTQLDTIRFRALIAQ 158
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 52.4 bits (120), Expect = 1e-05
Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 2/156 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A L + T + + D+ P + DL+ + + G E + A
Sbjct: 15 VGASTAYALMFKNICTEIIIVDVNPDIVQAQVLDLADAASISHTPIRAGSAEEAG---QA 71
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
D+VVI AG ++ G R L N +++ I + P A++ ++ NPV+ I +
Sbjct: 72 DIVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPVD----ILTH 127
Query: 542 VLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
+ K PN+V+G T LD R +G++ V+
Sbjct: 128 IAKTLSGLPPNQVIGSGTYLDTTRLRVHLGDVFDVN 163
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 52.0 bits (119), Expect = 1e-05
Identities = 43/144 (29%), Positives = 68/144 (47%), Gaps = 6/144 (4%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNT---PAKVSGHKGPEELSAAI 352
+G +A + L T + L D+ G A D SH + + H G E
Sbjct: 15 VGSAVANKIADFQLATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIKFHLGDYE---DC 71
Query: 353 KDADVVVIPAGVPRKPGMTRD--DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 526
KDA+++VI AG +PG T D L TNA I+ + I + +A++ +ITNP++
Sbjct: 72 KDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLD--- 128
Query: 527 PIASEVLKKAGVYDPNRVLGVTTL 598
+A+ V+ Y N +LG T+
Sbjct: 129 -VATYVVSTQFDYPRNLILGTGTM 151
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 51.6 bits (118), Expect = 2e-05
Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +2
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
AD+VVI AG + G TR D+ NA I +IA I + APKA++ +++NP + +A
Sbjct: 71 ADIVVITAGAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNPCDI---VAH 127
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
+ G ++PN+V+ +D R + V N VD
Sbjct: 128 FITTNTG-FEPNKVISSGCVIDTARLMSIVA--NRVD 161
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 51.2 bits (117), Expect = 2e-05
Identities = 38/115 (33%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
IG +A L L LYD A GVA ++ H ++ A+ DA
Sbjct: 18 IGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGL--NLTFTSDIKEALTDA 75
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNPVNST 523
+V G PRK GMTR+DL NA I + I P V II NP + T
Sbjct: 76 KYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNPADIT 130
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 51.2 bits (117), Expect = 2e-05
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Frame = +2
Query: 236 LALYDI--APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMT 409
LALYD A V V DL+H + G ++++ A +VV+ AG + PG +
Sbjct: 46 LALYDTNSAKVRAEVL-DLNHGSQFVPECRVGGSDDIAVTAGSA-IVVVTAGAKQHPGQS 103
Query: 410 RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV 589
R DL N ++ + + + +++P A+V +TNPV+ AS V+ P ++ G
Sbjct: 104 RLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTNPVDVVTYAASSVVDA----QPGQIFGT 159
Query: 590 -TTLDVVRAATFVGE 631
T LD R V +
Sbjct: 160 GTVLDSSRFRYLVAQ 174
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 51.2 bits (117), Expect = 2e-05
Identities = 43/153 (28%), Positives = 72/153 (47%), Gaps = 3/153 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A L LV + +YD+ P+ DL H +S +AA++DA
Sbjct: 12 VGGETAFLSAALGLVDEIVVYDVYEPLLRAQVLDLQHTGIDVAISTE------TAAMRDA 65
Query: 362 DVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
D+ V AG PR P + TR DL N + + + + + P +++ +TNP+++
Sbjct: 66 DIFVFAAGTPRTPDIKTRADLLEANIPVAKRCS-ELLEGFPGVVIS-VTNPMDAN---NY 120
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEI 634
+ K G+ D R +G + LD R A F+ E+
Sbjct: 121 GLWKMMGI-DRRRCIGFGSQLDSARFAGFLREV 152
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 50.4 bits (115), Expect = 4e-05
Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Frame = +2
Query: 350 IKDADVVVI-PAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 526
+ D+D+++I AGV K G TR D + NA I+R + + AP +IV II+NPV+
Sbjct: 71 LADSDIIIIVTAGVQPKLGQTRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVDVLT 130
Query: 527 PIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
IA +A N + G T LD R +G+
Sbjct: 131 RIAQATSTRA----ENLIFGSGTVLDTARLRYQLGK 162
>UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Apis
mellifera|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Apis mellifera
Length = 221
Score = 50.0 bits (114), Expect = 5e-05
Identities = 22/53 (41%), Positives = 36/53 (67%)
Frame = +2
Query: 452 IALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVR 610
+A +AQ +++VA+ PV +T+P SE+ K AG +DP+R++G T LD +R
Sbjct: 1 MAEQMAQFNSESLVAVFVRPVTATLPTVSEIYKLAGWWDPDRIIGSTALDRMR 53
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 1/98 (1%)
Frame = +2
Query: 260 VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 439
+ GV +L P S G E S +D DV V G PRKPGM R DL N +
Sbjct: 89 ILQGVELELQDGAYPLLKSIKTGSNE-SILFQDVDVAVFIGGFPRKPGMERKDLLTINGN 147
Query: 440 IVRDIALSIAQNAPKAIVA-IITNPVNSTVPIASEVLK 550
I + ++ A K + ++ NP N+ I +E K
Sbjct: 148 IFKKQGQALDTVAKKTCKSLVVANPANTNCLILAETAK 185
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
2 - Clostridium acetobutylicum
Length = 320
Score = 48.8 bits (111), Expect = 1e-04
Identities = 42/145 (28%), Positives = 64/145 (44%), Gaps = 4/145 (2%)
Frame = +2
Query: 224 LVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 400
L++ + + DI G A D SH + A K DA ++VI AG KP
Sbjct: 29 LLSEVVIIDINDNKAKGEALDASHTTSFAYSPNVKVRAGNYEDCADAQIIVITAGPSLKP 88
Query: 401 GMTRDDLF--NTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPN 574
D L +TN + I +I + AI+ ++TNPV+ IA+ + Y N
Sbjct: 89 DDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVD----IATYYCQNNFDYPKN 144
Query: 575 RVLGV-TTLDVVRAATFVGEINGVD 646
+++G T LD R +G+ VD
Sbjct: 145 KIIGTGTLLDTARMRKIIGKKYNVD 169
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +2
Query: 341 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAIITNPVN 517
+ A KDADV ++ PR PGM R DL N I +I + A P V ++ NP N
Sbjct: 77 AVAFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGKYANPNVKVLVVGNPAN 136
Query: 518 STVPIASEVLKKAGVYDPNRVLGVTTLDVVRA 613
+ IA + K G + LD RA
Sbjct: 137 TNAYIAMKSAMKHGRVKAKNFTAMLRLDHNRA 168
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 48.0 bits (109), Expect = 2e-04
Identities = 48/167 (28%), Positives = 66/167 (39%), Gaps = 4/167 (2%)
Frame = +2
Query: 143 QRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSH--MNTPAKV 313
QRN +G A L + L + D+ G A DL+H + P
Sbjct: 3 QRNINRVALIGAGSVGSSYAFALLNQSITEELVIIDVNEDKAMGDAMDLNHGKIFAPNPT 62
Query: 314 SGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIV 493
G + K+AD+V I AG +KPG TR DL N I + + + + I
Sbjct: 63 KTWYGNYD---DCKEADIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIF 119
Query: 494 AIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
I TNPV+ I + K RV+G T LD R +GE
Sbjct: 120 LIATNPVD----ILTYATWKFSGLPKERVIGSGTILDSGRFRFLLGE 162
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 47.6 bits (108), Expect = 3e-04
Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = +2
Query: 410 RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV 589
RDDL N+ I+RD+ +I + AP+A V +ITNP++ V + +LK G + N V+G+
Sbjct: 143 RDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMDVMVHL---MLKVTG-FPKNMVVGM 198
Query: 590 -TTLDVVRAATFVGEINGVD 646
LD R ++ E GV+
Sbjct: 199 GGLLDSSRMNCYIAEKLGVN 218
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
n=2; Bacteria|Rep: Lactate/malate dehydrogenase
precursor - Bacillus coagulans 36D1
Length = 327
Score = 47.2 bits (107), Expect = 4e-04
Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 2/126 (1%)
Frame = +2
Query: 275 AADLSHM-NTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRD 451
A L++M NT K + + I A V+P+ P R L TNA++VR+
Sbjct: 51 ATALTYMPNTSVKAGDYSECADADVIICAAGPSVLPSEKDEMPD--RAGLARTNAAVVRE 108
Query: 452 IALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVG 628
+ I + +A++ ITNP+++ V IA Y R+ G T LD R V
Sbjct: 109 VMAGITKYTKEAVIIFITNPLDTIVYIAENEFG----YSKGRIFGTGTMLDSARLRQLVA 164
Query: 629 EINGVD 646
E +D
Sbjct: 165 ENYSID 170
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 47.2 bits (107), Expect = 4e-04
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
Frame = +2
Query: 353 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
K++D+V+ AG RK G +R++L N SI+ D A I + I+TNPV+ +
Sbjct: 68 KNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVDFLL-- 125
Query: 533 ASEVLKKAGVYDPNRVLGVT-TLDVVR 610
L ++G++ +++ + LD R
Sbjct: 126 --NTLYESGIFSSKKIIAMAGVLDNAR 150
>UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
genitalium
Length = 312
Score = 47.2 bits (107), Expect = 4e-04
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +2
Query: 350 IKDADVVVIPAGVPRKPG-MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 526
+KD D + I AG P+K G TR L N I++ IA I ++ + I +NPV+
Sbjct: 69 LKDYDFIFISAGRPQKQGGETRLQLLEGNVEIMKSIAKEIKKSGFNGVTLIASNPVD--- 125
Query: 527 PIASEVLKKAGVYDPNRVLGVTTL 598
I S K ++PN+V+G TL
Sbjct: 126 -IMSYTYLKVTGFEPNKVIGSGTL 148
>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
dehydrogenase A chain (LDH-A) (LDH muscle subunit)
(LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
subunit) (LDH-M) - Apis mellifera
Length = 348
Score = 46.8 bits (106), Expect = 5e-04
Identities = 43/151 (28%), Positives = 69/151 (45%), Gaps = 2/151 (1%)
Frame = +2
Query: 197 LALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVV 373
+A+L K+ L + L D+ + A D+SH G ++ S A +DA V V
Sbjct: 49 IAILFKR--LASELVFIDVNEELAKAEAEDISHGAAFLGNPKIIGTKDYSLA-RDATVCV 105
Query: 374 IPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKK 553
I G L N +I +D+ + + AP +I+ I+T PV+ I S K
Sbjct: 106 ITIGDRSTNEQDPSTLLEQNLNIFKDVIPKVCKYAPNSILLIVTAPVD----ILSYAAMK 161
Query: 554 AGVYDPNRVLGV-TTLDVVRAATFVGEINGV 643
+ P+RV+G+ T LD R F+ + G+
Sbjct: 162 LSGFPPHRVVGLGTFLDSCRFQYFIAQKLGI 192
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 45.6 bits (103), Expect = 0.001
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 269 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 448
GVA +L P +SG + + A KD D ++ PRK GM R +L + N I +
Sbjct: 53 GVAMELVDCAFPL-LSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQ 111
Query: 449 DIALSIAQNA-PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFV 625
+I ++A P + +I NP N+ + S L K V ++ LD RA V
Sbjct: 112 IQGAAINEHAKPTCRILVIGNPANTNALVLSTQLTK---IPKTNVTAMSRLDHNRA---V 165
Query: 626 GEING 640
G++ G
Sbjct: 166 GQVAG 170
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 45.6 bits (103), Expect = 0.001
Identities = 44/144 (30%), Positives = 61/144 (42%), Gaps = 2/144 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A L L LA+ D+ T G DL+H P + +DA
Sbjct: 26 VGIAYAYTLVNQGLTDHLAIIDLDERKTWGHVQDLNHA-VPWSHHNTRVTVGTYEDCRDA 84
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
+V I AG +KPG TR DL N +I + I + + I + +NPV+ I S
Sbjct: 85 AMVCICAGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNPVD----ILSY 140
Query: 542 VLKKAGVYDPNRVLGV-TTLDVVR 610
K D +RV+G T LD R
Sbjct: 141 ATWKFSGMDSSRVIGSGTILDTAR 164
>UniRef50_Q014D4 Cluster: Chromosome 08 contig 1, DNA sequence; n=3;
Eukaryota|Rep: Chromosome 08 contig 1, DNA sequence -
Ostreococcus tauri
Length = 1453
Score = 44.8 bits (101), Expect = 0.002
Identities = 38/133 (28%), Positives = 60/133 (45%)
Frame = -1
Query: 571 RVVHSRLLEHFRGNRHCRVNRVCDDGHNSFGCILSNGQSNVTDNGSISVE*VITGHSRFT 392
RVV + LEH RG+ + V+ V D H G S+ + ++ + E V+ H+R
Sbjct: 5 RVVTTASLEHLRGDGNRGVHGVGYDVHQRVGTRTSDRFAERANDPGVDAEQVVPRHARLA 64
Query: 391 GYSCWDDYNISIFDGC**LLRSLVAADLGWGVHVGKVGCDAGGHRRYVV*SQPGHQRILL 212
+ DD ++ L S V A ++V +V H R VV S+ H R+ L
Sbjct: 65 RHPGGDDDQVAPSQTRVQLGVSHVRAHFRSRINVRQVHPHPSDHGRDVVQSELSHARVRL 124
Query: 211 Q*KGQRLADTTGG 173
+ +RL D + G
Sbjct: 125 DERRERLTDPSRG 137
>UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n=1;
Ostreococcus tauri|Rep: Chromosome 06 contig 1, DNA
sequence - Ostreococcus tauri
Length = 131
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/37 (59%), Positives = 24/37 (64%)
Frame = -2
Query: 375 MTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPG 265
M TTS S AA SS+ P +P T A VF E SAATPG
Sbjct: 1 MITTSQSFSAAPSSASPAYPFTCAAVFTCETSAATPG 37
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +2
Query: 347 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI-VAIITNPVNS 520
A KDADV + +PRKPGM R DL N I + + A + V ++ NP N+
Sbjct: 79 AFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKSTVKVLVVANPSNT 137
>UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
gallisepticum|Rep: L-lactate dehydrogenase - Mycoplasma
gallisepticum
Length = 323
Score = 44.0 bits (99), Expect = 0.003
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 7/106 (6%)
Frame = +2
Query: 350 IKDADVVVIPAGVPRKPG------MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 511
+KDADVV I A +P P R L N I+ +IAL + + K + I TNP
Sbjct: 68 LKDADVVAITASIPTVPTADGEVFTDRLQLMTANVKILNEIALELKRVGFKGLSIIPTNP 127
Query: 512 VNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
+ + + V +K +DP++++ L+ +R + E GV+
Sbjct: 128 CD----VMAGVYQKVTGFDPHKIISTGCQLETMRTRKMISEALGVN 169
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Frame = +2
Query: 413 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVT 592
DDL + N S+ + +A ++ Q+AP A V + TNP++S V K R++G+
Sbjct: 16 DDLLDINLSVTKKVATAVKQHAPDAFVILTTNPLDSIV----YAFHKLSGLPAERIIGMA 71
Query: 593 -TLDVVRAATFVGEINGV 643
LD R T++ G+
Sbjct: 72 GALDTARFRTYIAMETGL 89
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 43.6 bits (98), Expect = 0.005
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +2
Query: 311 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI 490
V+G +++ A KD DV + PRK GM R DL N I +++ A K +
Sbjct: 46 VAGIVWTDKIEEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDV 105
Query: 491 -VAIITNPVNSTVPIA 535
V ++ NP N+ IA
Sbjct: 106 KVLVVGNPANTNCLIA 121
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 43.6 bits (98), Expect = 0.005
Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 1/107 (0%)
Frame = +2
Query: 326 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAII 502
G +L A +D DV + P+KP D F NASI + +++ A P V +I
Sbjct: 69 GTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFAKPTVKVLVI 128
Query: 503 TNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGV 643
P N+ +A + A P +T LD RA + + GV
Sbjct: 129 GMPTNTNALVA---MTAAVNLSPKNFCAMTRLDHNRAVYSIAQKLGV 172
>UniRef50_O34358 Cluster: Probable serine protease do-like htrA;
n=1; Bacillus subtilis|Rep: Probable serine protease
do-like htrA - Bacillus subtilis
Length = 449
Score = 43.2 bits (97), Expect = 0.006
Identities = 33/108 (30%), Positives = 50/108 (46%)
Frame = +2
Query: 281 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 460
DLS T VSG +S + + + VI PG + L NT+ IV ++
Sbjct: 248 DLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSM 307
Query: 461 SIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDV 604
I+++ + I I P N PIA E+L K + P +GV+ LD+
Sbjct: 308 KISEDDVEGIGFAI--PSNDVKPIAEELLSKGQIERP--YIGVSMLDL 351
>UniRef50_UPI00015974E8 Cluster: HtrA; n=1; Bacillus
amyloliquefaciens FZB42|Rep: HtrA - Bacillus
amyloliquefaciens FZB42
Length = 450
Score = 42.7 bits (96), Expect = 0.008
Identities = 32/108 (29%), Positives = 51/108 (47%)
Frame = +2
Query: 281 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 460
DLS T VSG +S + ++ + VI PG + L NT+ I+ ++
Sbjct: 249 DLSRTVTQGIVSGLNRTVSISTSAGESSINVIQTDAAINPGNSGGPLLNTDGKIIGINSM 308
Query: 461 SIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDV 604
I+++ + I I P N PIA E+L K V P +GV+ +D+
Sbjct: 309 KISESDVEGIGFAI--PSNDVKPIAEELLTKGQVERP--YIGVSMIDL 352
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 42.7 bits (96), Expect = 0.008
Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Frame = +2
Query: 359 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAS 538
ADVV+I AGV PG T SI++ I + P AI+ ++ NPV++ +A
Sbjct: 70 ADVVIITAGVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPVDTLTTLAQ 129
Query: 539 EVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEING 640
++ AG+ +V+GV T +D +R V G
Sbjct: 130 DI---AGL-PRKQVIGVGTCIDSLRLQDEVSRFLG 160
>UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1;
Staphylococcus haemolyticus JCSC1435|Rep: L-lactate
dehydrogenase - Staphylococcus haemolyticus (strain
JCSC1435)
Length = 318
Score = 42.3 bits (95), Expect = 0.011
Identities = 45/152 (29%), Positives = 65/152 (42%), Gaps = 5/152 (3%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAK---VSGHKGPEELSAAI 352
+G A + LV +A+ DI DL+H TP V+ H G E
Sbjct: 14 VGSAFAHAIVAKGLVDEMAIIDIDEDKAKADVWDLNHA-TPFGDNFVNVHVGQYE---DF 69
Query: 353 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
KDAD+VVI A G TR L N I + I + + +NPV+ I
Sbjct: 70 KDADIVVICASAKLAKGETRLKLLEDNVDIFVPMIQRIVDSGFDGYFVLPSNPVD----I 125
Query: 533 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFV 625
S V+K+ + N+++G T+LD R F+
Sbjct: 126 MSYVVKRVSNFPKNKIIGSGTSLDTARFQFFL 157
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 326
Score = 41.9 bits (94), Expect = 0.014
Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 2/144 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G LA L + T + L D + G DLS T G + + A
Sbjct: 18 VGATLAYTLILQSICTEVLLVDPKTSLLDGQVRDLSDA-TSRSTKVRSGTHQEAG---QA 73
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
D+VVI AG +K G +R L N +I+ I S+ + ++ ++ NPV+ V A
Sbjct: 74 DIVVITAGAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVDILVYFARM 133
Query: 542 VLKKAGVYDPNRVLGV-TTLDVVR 610
+ +G+ + N+VLG T+LD R
Sbjct: 134 M---SGLPE-NQVLGTGTSLDSAR 153
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 41.5 bits (93), Expect = 0.018
Identities = 34/118 (28%), Positives = 51/118 (43%), Gaps = 1/118 (0%)
Frame = +2
Query: 269 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 448
GV +L P ++G + + A KD D ++ PR PGM R DL NA I
Sbjct: 55 GVIMELEDCAFPL-LAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFT 113
Query: 449 DIALSIAQNAPKAI-VAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAAT 619
++ A + + V ++ NP N+ IA +K A + LD RAA+
Sbjct: 114 AQGKALNAVASRNVKVLVVGNPANTNAYIA---MKSAPDLPAKNFTAMLRLDHNRAAS 168
>UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to
Ecdysone-inducible gene L3 CG10160-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Ecdysone-inducible
gene L3 CG10160-PA - Apis mellifera
Length = 368
Score = 41.1 bits (92), Expect = 0.024
Identities = 39/149 (26%), Positives = 65/149 (43%), Gaps = 2/149 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
IG A+ + + + + L D A A D+ H+ G E+S + A
Sbjct: 59 IGIACAIAILMRRMASEVCLIDHDANKASAEAEDIQHVGFFLGCPLVTGTSEISTVKESA 118
Query: 362 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASE 541
V++ P PG ++ N + + I +IA+ A K+++ I+T P + + S
Sbjct: 119 VVIICTPETP--PGENQN--VKHNLKVFKKIIPAIARFAAKSVLLIVTRPAD----VMSY 170
Query: 542 VLKKAGVYDPNRVLGVTTL-DVVRAATFV 625
+ K + NRVLG+ TL D R FV
Sbjct: 171 IAWKLSGFPSNRVLGIGTLIDCARLQDFV 199
>UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Lactate/malate
dehydrogenase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 283
Score = 40.7 bits (91), Expect = 0.032
Identities = 43/157 (27%), Positives = 70/157 (44%), Gaps = 3/157 (1%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSH-MNTPAKVSGHKGPEELSAAIKD 358
IG +A + L L+DI+ P+ D+ H M+ P + A +KD
Sbjct: 12 IGGEVAYVSALRKFADELVLFDISEPLQHAQKLDIIHGMDIPVSTN--------PADLKD 63
Query: 359 ADVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 535
AD + AG R P + TR DLF+ N I ++ + + + K IV +TNP++ +
Sbjct: 64 ADYCIFSAGYSRSPNIKTRADLFDKNLPIAKESSELLKGFSGKLIV--VTNPMD----VF 117
Query: 536 SEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEINGVD 646
+ K D ++V+G L R T V G++
Sbjct: 118 TWYFAKKSCLDESQVVGFGGLLDSRRFTVVLRSIGIE 154
>UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3;
Bifidobacterium longum|Rep: L-lactate dehydrogenase 1 -
Bifidobacterium longum
Length = 316
Score = 40.7 bits (91), Expect = 0.032
Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
Frame = +2
Query: 344 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 523
A KDAD+VVI G R +V ++ ++ + ++ +++NPV+
Sbjct: 70 ADCKDADIVVITVGRKPPANSNRMAELGFTVGLVGEVVDNVMASGFDGVIVMVSNPVD-- 127
Query: 524 VPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
+A K++G+ +VLG T LD R T +GE G+D
Sbjct: 128 -VMAWYAWKRSGL-PRTQVLGTGTALDTSRLKTIIGEETGLD 167
>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 237
Score = 39.9 bits (89), Expect = 0.056
Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 5/159 (3%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDA 361
+G A L + L L D A G DLS A + SA ++A
Sbjct: 18 VGAAAAYALVLGSIADELLLVDTRAAWRDGQVRDLSD----AAYASRSKTRVYSATYREA 73
Query: 362 ---DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 532
D+VVI AG G T D N SIVR I + ++ I+ NPV+ +
Sbjct: 74 SQCDIVVITAGSKYLYGQTSMDYLYRNTSIVRSIINEMKPFRSDTVLLIVANPVDLMTSL 133
Query: 533 ASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
A E+ +VLG T LD +R + + GV+
Sbjct: 134 AKELSNLPSA----QVLGSGTFLDSIRLRGLLADETGVN 168
>UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 321
Score = 37.9 bits (84), Expect = 0.23
Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 7/106 (6%)
Frame = +2
Query: 350 IKDADVVVIPAG----VPRKP--GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 511
+ +ADV+++ AG P G R +L TN I+R I A + I +NP
Sbjct: 72 LSNADVIIMTAGPSIDASNGPATGAARRELAATNGKIIRSTMTQITSRNHDAAIIICSNP 131
Query: 512 VNSTVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
+++ V IAS + VLG T LD R V + GVD
Sbjct: 132 LDALVHIASTEFD----HPQGLVLGTGTILDSARMCRVVADHLGVD 173
>UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 492
Score = 36.7 bits (81), Expect = 0.52
Identities = 19/74 (25%), Positives = 36/74 (48%)
Frame = +2
Query: 332 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 511
++LS A+ D D VV G +D+ S ++D+ LSI +N ++ +P
Sbjct: 173 DDLSLAVADCDGVVYVNGPDTSEISNENDIERLFVSSIQDVFLSIKRNGKSVRRVVLISP 232
Query: 512 VNSTVPIASEVLKK 553
+S P+ + ++ K
Sbjct: 233 ASSIFPVETTLVAK 246
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 36.3 bits (80), Expect = 0.69
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
Frame = +2
Query: 338 LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI--VRDIALSIAQNAPKAIVAIITNP 511
L+ A D + VPR PGM R DL N I ++ AL+ A A + ++ NP
Sbjct: 76 LNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR-DAKIFVVGNP 134
Query: 512 VNSTVPIA 535
VN+ IA
Sbjct: 135 VNTNCWIA 142
>UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 303
Score = 35.9 bits (79), Expect = 0.91
Identities = 32/150 (21%), Positives = 70/150 (46%), Gaps = 1/150 (0%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDAD 364
+G +A L N L L + G + D++ +G ++ S I +D
Sbjct: 13 VGASIAFLCVSNGLDDVLLVNTTKEKAIGESLDVASAIPANSKFSIRGTDDYSELI-GSD 71
Query: 365 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEV 544
+V+I A V +++ + +++++IA I + P AIV +++NP++ + +
Sbjct: 72 IVIIAASVGIYTKHRAENI-DHQVAMIKNIAKKIKKYCPSAIVLLVSNPLD----VLTYF 126
Query: 545 LKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
+K + +V+G+ ++LD R ++ E
Sbjct: 127 FQKTTGFSRFKVIGIASSLDTSRFRYYISE 156
>UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finger
protein 160, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to Zinc finger protein 160, partial -
Ornithorhynchus anatinus
Length = 912
Score = 35.5 bits (78), Expect = 1.2
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = +1
Query: 199 GPSTEAESSGDQAGFIRHSACDPRRRSRPFPHEHPSQGQRPQG 327
GP S G G +R+SA DP RRS P P +R +G
Sbjct: 143 GPGEPVRSGGAGEGAVRNSALDPTRRSHPSPIPPRGSRERDEG 185
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 35.5 bits (78), Expect = 1.2
Identities = 37/144 (25%), Positives = 72/144 (50%), Gaps = 9/144 (6%)
Frame = +2
Query: 185 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHK--GPEELSAAIK 355
IG LA ++ + L + L+D P G A D+ H P S G E++ IK
Sbjct: 17 IGCALAHMICEKNLGD-VVLHDFRKDLPKGRALDILHTR-PLNRSRINILGTNEITD-IK 73
Query: 356 DADVVVIPAGVPRKPGMTRDD------LFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 517
D+ VVV+ V + D+ ++ +N +++++A S+ ++ P+A V + T+PV+
Sbjct: 74 DSLVVVVTIEVSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQAFVVVTTSPVD 133
Query: 518 STVPIASEVLKKAGVYDPNRVLGV 589
++VL++ P+++ G+
Sbjct: 134 ----CMAKVLQEHANIPPHKICGM 153
>UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=3;
Lactobacillales|Rep: Enzyme with possible activities of
L-2- hydroxyisocaproate/malate/lactate dehydrogenase -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 304
Score = 35.1 bits (77), Expect = 1.6
Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Frame = +2
Query: 350 IKDADVVVIPAGVPR--KPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 523
+ DA+VV+ G KPG R N V+ + + Q ++ +I+NPV+
Sbjct: 67 LTDAEVVISALGHIELIKPGGDRFTELKANTPEVQQVGSDLKQAGFNGVLIVISNPVD-- 124
Query: 524 VPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGEINGVD 646
+ + + +KA N+V G T LD R +G+ +D
Sbjct: 125 --VITGIYQKATGLPANQVFGTGTYLDTARLKRALGDTLAID 164
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 35.1 bits (77), Expect = 1.6
Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Frame = +2
Query: 329 PEELSAAIKDADVVVIPAGVPR-KPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 505
P L KDADVVVI A +P K R L NA +++ A + K IV +
Sbjct: 62 PGTLLEDSKDADVVVITASIPADKTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAA 121
Query: 506 NP 511
NP
Sbjct: 122 NP 123
>UniRef50_Q8NQ95 Cluster: Predicted nucleoside-diphosphate-sugar
epimerases; n=4; Corynebacterium|Rep: Predicted
nucleoside-diphosphate-sugar epimerases -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 221
Score = 34.7 bits (76), Expect = 2.1
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 5/110 (4%)
Frame = +2
Query: 332 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR-DIALSIAQNAPKAI-VAIIT 505
E+ + +KD DVVV AG K G + +A+I D A S+ + AP+ I V+ I
Sbjct: 62 EDWADLLKDFDVVVWSAGNGGKNGADATYAIDRDAAIASIDGAASLGEKAPRYIMVSYIG 121
Query: 506 NPVNSTVPIASEVLKKAGVYDPNRVLGVTTLD---VVRAATFVGEINGVD 646
+ ++ P AS + L T LD + AA + E+NGV+
Sbjct: 122 SSTHTIDPSASFYPYAESKKAADEHLSSTNLDYLILAPAALTLDEVNGVE 171
>UniRef50_UPI000049A32B Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 1054
Score = 34.3 bits (75), Expect = 2.8
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Frame = -1
Query: 550 LEHFRGNRHCRVNRVCDDGHNS---FGCILSNGQSNVTDN 440
+E F N HC N C DG+N+ F C+ S+ + + DN
Sbjct: 457 VECFSYNNHCLTNCKCQDGYNATSLFSCVTSSCGNGINDN 496
>UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n=2;
Danio rerio|Rep: UPI0000D8BD94 UniRef100 entry - Danio
rerio
Length = 732
Score = 34.3 bits (75), Expect = 2.8
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 4/116 (3%)
Frame = +2
Query: 188 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHK---GPEELSAAIKD 358
G P A+LL NP T+L + P+ H N A+++GH + S +
Sbjct: 285 GMPNAVLLSSNPNQTQLNQLTLNPLQLN-----HHPNCSAQLTGHPLTLPRPKFSYMNTN 339
Query: 359 ADVVVIPAGVPRKPGMTRDDLFN-TNASIVRDIALSIAQNAPKAIVAIITNPVNST 523
V+ G + + D FN TN ++ ++ I+ PK ++ PVN T
Sbjct: 340 GSAAVVFLGYTAMENLLKADFFNATNDTVNTMMSSVISVTLPKTTNTALSKPVNFT 395
>UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 488
Score = 34.3 bits (75), Expect = 2.8
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = -2
Query: 114 FCTARAAGFRARENIFVVC-LTCIYVYI*TIST*PSRP 4
FC+ R F R +F+ C LTC+Y + IST P+ P
Sbjct: 320 FCSKRIKNFGMRPTMFIGCFLTCLYCALVVISTPPTAP 357
>UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 258
Score = 33.9 bits (74), Expect = 3.7
Identities = 20/41 (48%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Frame = +1
Query: 217 ESSGDQAGFIRHSACDPRRRSRPFPHE-HPSQGQRPQGT*G 336
E GDQ RH AC R S P E P GQRP GT G
Sbjct: 6 EGRGDQERTRRHRACPGCRGSEVSPGEGAPGSGQRPAGTSG 46
>UniRef50_Q81Y95 Cluster: Serine protease; n=16; Bacillaceae|Rep:
Serine protease - Bacillus anthracis
Length = 413
Score = 33.9 bits (74), Expect = 3.7
Identities = 26/86 (30%), Positives = 38/86 (44%)
Frame = +2
Query: 356 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 535
D + VI PG + LFN N I+ + IAQ + I I P+N P+
Sbjct: 238 DWNAQVIQTDAAINPGNSGGALFNQNGEIIGINSSKIAQQEVEGIGFAI--PINIAKPVI 295
Query: 536 SEVLKKAGVYDPNRVLGVTTLDVVRA 613
+ K V P +GV +L+ V+A
Sbjct: 296 ESLEKDGVVKRPALGVGVVSLEDVQA 321
>UniRef50_Q608X6 Cluster: Hydrophobe/amphiphile Efflux-1 (HAE1)
family protein; n=17; Proteobacteria|Rep:
Hydrophobe/amphiphile Efflux-1 (HAE1) family protein -
Methylococcus capsulatus
Length = 1054
Score = 33.9 bits (74), Expect = 3.7
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = -2
Query: 378 GMTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPGVTGAMSYKASLV 229
G+T AS+ A +GP+ +TL ++ SA PG+TG M + +LV
Sbjct: 436 GLTPKEASIKAMSEMTGPVIGITLVLTAVFLPSAFLPGITGQMFRQFALV 485
>UniRef50_A6ESK5 Cluster: LysM-repeat protein; n=1; unidentified
eubacterium SCB49|Rep: LysM-repeat protein -
unidentified eubacterium SCB49
Length = 669
Score = 33.9 bits (74), Expect = 3.7
Identities = 18/75 (24%), Positives = 36/75 (48%)
Frame = +2
Query: 383 GVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGV 562
G+ R G+T D+L N + +D+++ N P V N ++ + V +K G
Sbjct: 199 GIARMYGITMDELITMNPGLTKDLSMGSVLNVPSKTVTGSAN-IDDELYSFYTVKQKEGF 257
Query: 563 YDPNRVLGVTTLDVV 607
Y + LG++ +++
Sbjct: 258 YRLEKNLGLSEEEII 272
>UniRef50_A6CMQ6 Cluster: HtrA; n=1; Bacillus sp. SG-1|Rep: HtrA -
Bacillus sp. SG-1
Length = 423
Score = 33.9 bits (74), Expect = 3.7
Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Frame = +2
Query: 281 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 460
DLS T VS + + ++++ VI PG + L N+N +V +L
Sbjct: 227 DLSRTVTQGIVSAVDRTISVPTSAGESELNVIQTDAAINPGNSGGALINSNGELVGINSL 286
Query: 461 SIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTL-DVVR 610
I+ + + + I P +PI +E+++ V P +G+T+L DV R
Sbjct: 287 KISTSGVEGLGFAI--PSKDFLPIVNEIIETGKVERPYIGIGMTSLADVPR 335
>UniRef50_Q9VY98 Cluster: CG9941-PA; n=5; Drosophila|Rep: CG9941-PA
- Drosophila melanogaster (Fruit fly)
Length = 789
Score = 33.9 bits (74), Expect = 3.7
Identities = 25/119 (21%), Positives = 46/119 (38%)
Frame = +2
Query: 239 ALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDD 418
AL I V G++ + H NTP +G P ++ ++ G P+ R+
Sbjct: 363 ALLQIRAVQKGISTHVLHQNTPTSAAGEPAPVDVPPGYIPVSLIEALNGPPQYVARARNS 422
Query: 419 LFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTT 595
+ V D A ++A + + T+P+ S+ ++ K A +G T
Sbjct: 423 EHD-----VTDSAATVAASTMTSADIKATSPIKSSSQRRPKIKKNASTCTSTSEVGTIT 476
>UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3;
Lactococcus lactis|Rep: L-lactate dehydrogenase 3 -
Lactococcus lactis subsp. lactis (Streptococcus lactis)
Length = 323
Score = 33.9 bits (74), Expect = 3.7
Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Frame = +2
Query: 350 IKDADVVVIPAGVPRKP-GMTRD--DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 520
+ DAD+VV+ A P G D L ++RDI I + +NPV+
Sbjct: 72 VSDADIVVLSANAPSATFGKNPDRLQLLENKVEMIRDITRKTMDAGFDGIFLVASNPVDV 131
Query: 521 TVPIASEVLKKAGVYDPNRVLGV-TTLDVVRAATFVGE 631
+ +EV +G+ +RV+G T L+ R V E
Sbjct: 132 LAQVVAEV---SGL-PKHRVIGTGTLLETSRMRQIVAE 165
>UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14749, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 778
Score = 33.5 bits (73), Expect = 4.9
Identities = 18/47 (38%), Positives = 21/47 (44%)
Frame = +1
Query: 160 GGRWCRRWYRPAFGPSTEAESSGDQAGFIRHSACDPRRRSRPFPHEH 300
G R R + P GP E G Q +RH A P RR R P +H
Sbjct: 554 GVRAPRGLHHPGAGPQRAHEGRGRQPAAVRHPAEPPGRRHRERPGDH 600
>UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein
precursor; n=1; Anabaena variabilis ATCC 29413|Rep:
Putative uncharacterized protein precursor - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 303
Score = 33.5 bits (73), Expect = 4.9
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +2
Query: 371 VIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI-ITNPVNS 520
++P G P KP T D+ +T ++ + L +NA KAI+ + NPVN+
Sbjct: 116 LVPEG-PSKPNPTAQDIVSTLGNLNLNSILVTRENADKAIIEVSFANPVNT 165
>UniRef50_Q0JLJ7 Cluster: Os01g0595100 protein; n=6; Oryza
sativa|Rep: Os01g0595100 protein - Oryza sativa subsp.
japonica (Rice)
Length = 837
Score = 33.5 bits (73), Expect = 4.9
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Frame = +2
Query: 287 SHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRK-PGMTRDDLFNTNASIVRDIALS 463
+H N P KV +GP A K+ VV G RK P +R+ +AS VR+ +
Sbjct: 264 NHQNRPQKVVRGRGPRRYEAVAKNNRDVV---GFQRKQPARSRESA--ASASAVRESGQT 318
Query: 464 IAQNAPKAIVAIITNPVNSTVPIASEVLKKAGVYDPN 574
+ NA + N VNS++ AS +G +P+
Sbjct: 319 L--NAQSEMAPPKKNVVNSSLNSASPPFYPSGASNPD 353
>UniRef50_A2XSM8 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 692
Score = 33.5 bits (73), Expect = 4.9
Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Frame = +2
Query: 284 LSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 463
L + T + G+KG E +K V+ + PG+TR + + + I I
Sbjct: 88 LQLLETDKEAGGNKGVSEKQIRLKIFSPNVLDITLVDLPGITRVPVGDQPSDIESRIRSM 147
Query: 464 IAQ--NAPKAIVAIITNPVNSTVPIASEVLKKAGVYDP--NRVLGV-TTLDVVRAAT 619
I Q P I+ +T P N+ + S+ L+ A + DP +R +GV T LD++ T
Sbjct: 148 IMQYIKHPSCIILAVT-PANADL-ANSDALQLAKLADPDGSRTIGVITKLDIMDRGT 202
>UniRef50_Q2UFR5 Cluster: Predicted protein; n=2; Aspergillus|Rep:
Predicted protein - Aspergillus oryzae
Length = 299
Score = 33.5 bits (73), Expect = 4.9
Identities = 25/101 (24%), Positives = 41/101 (40%)
Frame = +2
Query: 332 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 511
+ L+AA++ DVVV GV + N N I IA + + P ++ TNP
Sbjct: 58 KSLTAALQGVDVVVSTVGVAA--------VDNQNVLIDAAIAAGVKRFIPSEFSSVTTNP 109
Query: 512 VNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVRAATFVGEI 634
T+P+ S + K G + V+ F+ +
Sbjct: 110 KLETLPLYSSMFKIRNYLQEKTAAGELSWTVLACGAFLDSV 150
>UniRef50_A2R1L8 Cluster: Contig An13c0060, complete genome; n=2;
Aspergillus|Rep: Contig An13c0060, complete genome -
Aspergillus niger
Length = 332
Score = 33.5 bits (73), Expect = 4.9
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +2
Query: 197 LALLLKQNPLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVI 376
L +L ++ L + +IA + PGVA L ++ ++ +E+ +D DV+V
Sbjct: 51 LIILASRDILKAQQTAQEIANIAPGVATRLLELDLRSQAQVRNAAKEVLTYKEDIDVLVN 110
Query: 377 PAGVPRKP-GMTRDDL 421
AGV P +T D +
Sbjct: 111 NAGVMASPFSLTEDGI 126
>UniRef50_Q46780 Cluster: BfpF; n=4; Enterobacteriaceae|Rep: BfpF -
Escherichia coli
Length = 331
Score = 33.1 bits (72), Expect = 6.4
Identities = 20/78 (25%), Positives = 36/78 (46%)
Frame = -1
Query: 631 LADEGGSADYVQSGDAEHAVRVVHSRLLEHFRGNRHCRVNRVCDDGHNSFGCILSNGQSN 452
+A G AD V+S A+ + +VH L G R N +C+DG S + +G+
Sbjct: 251 IASAEGEADLVRSIIADGLLGIVHQELRFTENGQRSLSANILCNDGSASISSKIRSGKLE 310
Query: 451 VTDNGSISVE*VITGHSR 398
+ + I + ++ H +
Sbjct: 311 LL-SSEIEQQRIMLSHGK 327
>UniRef50_Q0SBH8 Cluster: Pyruvate dehydrogenase E1 component; n=7;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase E1
component - Rhodococcus sp. (strain RHA1)
Length = 817
Score = 33.1 bits (72), Expect = 6.4
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Frame = +2
Query: 377 PAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT-NP-VNSTVPIASEVLK 550
P VP G T T A++ R + L +++ AP A ++T +P V+ST +A L
Sbjct: 439 PPAVPADIGRTPSGTSTTQAALGRAL-LDLSREAPDAAKRVVTVSPDVSSTTNLAGW-LN 496
Query: 551 KAGVYDPN 574
K GV+ PN
Sbjct: 497 KVGVWSPN 504
>UniRef50_UPI0000D9F76A Cluster: PREDICTED: hypothetical protein,
partial; n=2; Macaca mulatta|Rep: PREDICTED:
hypothetical protein, partial - Macaca mulatta
Length = 517
Score = 32.7 bits (71), Expect = 8.5
Identities = 24/110 (21%), Positives = 43/110 (39%), Gaps = 1/110 (0%)
Frame = +2
Query: 221 PLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 400
P+ + + A PG D + TP +SA+++ ++ P + P
Sbjct: 183 PVTGEVTITTAAGEVPGRDKDDADATTPIATETATVATTISASVEPTTIMTSPQPLGEAP 242
Query: 401 GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP-VNSTVPIASEVL 547
G +DD + + + A + +AP IT P ST + EV+
Sbjct: 243 GRDKDD-SDATTPVATETATATTIDAPVEPTTTITTPQPASTAAVTDEVV 291
>UniRef50_Q91LF0 Cluster: ORF90; n=1; Shrimp white spot syndrome
virus|Rep: ORF90 - White spot syndrome virus (WSSV)
Length = 759
Score = 32.7 bits (71), Expect = 8.5
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +2
Query: 245 YDIAPVTPG--VAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPA-GVPRKPGMTRD 415
+D+ P TPG V + K +G +G EE ++ + + P PR PG RD
Sbjct: 664 FDLPPATPGRNVEEIIKAQRQAVKETGVRGEEE-----EEEEAFIAPIIRQPRTPGNFRD 718
Query: 416 DLFNTNASI 442
+L + N SI
Sbjct: 719 ELLDVNESI 727
>UniRef50_A7SI71 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1647
Score = 32.7 bits (71), Expect = 8.5
Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Frame = -2
Query: 393 RGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPGVTGAMS-YKASLVT 226
RG P+GM+TT++S ++D S L +T G + S+ TPG GA++ SLVT
Sbjct: 931 RGLPSGMSTTNSSTQSSDPS--VLGSVTSVGNLV--TSSLTPGFLGALAELVRSLVT 983
>UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone
demethylation protein 1B; n=56; Euteleostomi|Rep: JmjC
domain-containing histone demethylation protein 1B -
Homo sapiens (Human)
Length = 1336
Score = 32.7 bits (71), Expect = 8.5
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -3
Query: 167 RPPL*SSSVMWWKSSLHHFVQQ 102
RPPL SS WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 743,110,387
Number of Sequences: 1657284
Number of extensions: 16858566
Number of successful extensions: 56212
Number of sequences better than 10.0: 169
Number of HSP's better than 10.0 without gapping: 52525
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 56086
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 52892566912
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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