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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV021006
         (801 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000DB7078 Cluster: PREDICTED: similar to SPRY domai...    85   3e-15
UniRef50_UPI0000D56DC8 Cluster: PREDICTED: similar to SPRY domai...    85   3e-15
UniRef50_Q7PRH2 Cluster: ENSANGP00000025195; n=2; Culicidae|Rep:...    83   8e-15
UniRef50_UPI0000F21412 Cluster: PREDICTED: similar to Spsb3 prot...    75   2e-12
UniRef50_Q4S4U4 Cluster: Chromosome 2 SCAF14738, whole genome sh...    75   3e-12
UniRef50_Q6PJ21 Cluster: SPRY domain-containing SOCS box protein...    74   4e-12
UniRef50_UPI00005A11CE Cluster: PREDICTED: similar to SPRY domai...    74   5e-12
UniRef50_UPI0000F1E77D Cluster: PREDICTED: similar to conserved ...    64   3e-09
UniRef50_Q9VUW0 Cluster: CG10516-PA; n=1; Drosophila melanogaste...    64   4e-09
UniRef50_A7RJX3 Cluster: Predicted protein; n=2; Nematostella ve...    61   3e-08
UniRef50_Q9VMV3 Cluster: CG14041-PA, isoform A; n=8; Coelomata|R...    45   0.003
UniRef50_A7M6E3 Cluster: F-box/SPRY-domain protein 1; n=1; Duges...    36   1.2  
UniRef50_Q61CY5 Cluster: Putative uncharacterized protein CBG127...    35   2.7  
UniRef50_Q965N6 Cluster: Putative uncharacterized protein; n=4; ...    33   8.4  

>UniRef50_UPI0000DB7078 Cluster: PREDICTED: similar to SPRY
           domain-containing SOCS box protein SSB-3; n=2;
           Apocrita|Rep: PREDICTED: similar to SPRY
           domain-containing SOCS box protein SSB-3 - Apis
           mellifera
          Length = 298

 Score = 84.6 bits (200), Expect = 3e-15
 Identities = 35/72 (48%), Positives = 51/72 (70%)
 Frame = +3

Query: 495 FGYCRVRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEE 674
           +G   VRGN  +    ++YWEIKMLT  YGTDI++GVG+NKV++++ +  F S +G D E
Sbjct: 62  YGTAAVRGNKILEKGKYHYWEIKMLTPVYGTDIMVGVGTNKVDLNNTKHVFCSFLGLDRE 121

Query: 675 SYGLSYTGAVRH 710
           S+G SY G ++H
Sbjct: 122 SFGFSYQGYIQH 133



 Score = 36.7 bits (81), Expect = 0.68
 Identities = 17/45 (37%), Positives = 28/45 (62%)
 Frame = +1

Query: 373 CTCGEEQNLKEWSWERPPYVGSSWLVLTNDLKQVTFHPFYSSGTA 507
           C+CGE  N+ EW+W++     +  ++L+ +  +V FH  YS GTA
Sbjct: 24  CSCGEN-NVHEWAWDKEN--ATYTIILSKNDLEVKFHNGYSYGTA 65


>UniRef50_UPI0000D56DC8 Cluster: PREDICTED: similar to SPRY
           domain-containing SOCS box protein SSB-3; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to SPRY
           domain-containing SOCS box protein SSB-3 - Tribolium
           castaneum
          Length = 320

 Score = 84.6 bits (200), Expect = 3e-15
 Identities = 32/73 (43%), Positives = 57/73 (78%)
 Frame = +3

Query: 498 GYCRVRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEES 677
           G   +RG+ P+  N H++WE+KML++ YGTD+++GVG++++ ++D ++ F SL+G D+ES
Sbjct: 68  GTAALRGSKPLEKNRHHFWEMKMLSNLYGTDVMVGVGTSEITLADWRYRFFSLLGFDKES 127

Query: 678 YGLSYTGAVRHNS 716
           +G SY G V+H++
Sbjct: 128 WGYSYNGLVQHDN 140



 Score = 37.5 bits (83), Expect = 0.39
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = +1

Query: 373 CTCGEEQNLKEWSWERPPYVGSSWLVLTNDLKQVTFHPFYSSGTA 507
           C C +   +  W WE+      +  +L+ + ++VTFHP YSSGTA
Sbjct: 30  CDCADS-GIYNWIWEKQD---DTCALLSKNNREVTFHPVYSSGTA 70


>UniRef50_Q7PRH2 Cluster: ENSANGP00000025195; n=2; Culicidae|Rep:
           ENSANGP00000025195 - Anopheles gambiae str. PEST
          Length = 296

 Score = 83.0 bits (196), Expect = 8e-15
 Identities = 38/91 (41%), Positives = 60/91 (65%)
 Frame = +3

Query: 510 VRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEESYGLS 689
           VRGN P+    H+YWE+K+L+   GTDI+ G+G++KV++   QF+FTS++G D++S+G S
Sbjct: 88  VRGNEPLYRGRHHYWELKILSPLSGTDIMFGIGTDKVDLLRHQFSFTSVLGIDDQSWGYS 147

Query: 690 YTGAVRHNS*SHQRLGRLLLAAPSWSPGRLV 782
           Y G  +HN       G+L      +S GR++
Sbjct: 148 YRGLAQHN-------GQLKYYGKKFSRGRII 171


>UniRef50_UPI0000F21412 Cluster: PREDICTED: similar to Spsb3
           protein; n=1; Danio rerio|Rep: PREDICTED: similar to
           Spsb3 protein - Danio rerio
          Length = 508

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 31/71 (43%), Positives = 50/71 (70%)
 Frame = +3

Query: 498 GYCRVRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEES 677
           G   +RG+  +    H+ WEIKM +  YGTD+++G+G+++VN+   + +F SL+G DE+S
Sbjct: 143 GTAAIRGSKALSDGQHF-WEIKMTSPVYGTDMMVGIGTSEVNLDQFKHSFCSLLGTDEDS 201

Query: 678 YGLSYTGAVRH 710
           +GLSYTG + H
Sbjct: 202 WGLSYTGHLHH 212



 Score = 39.1 bits (87), Expect = 0.13
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
 Frame = +1

Query: 319 CPCWSKRSGPVPWKNLNL-CTCGEEQNLKEWSWERPPYVGSSWLVLTNDLKQVTFHPFYS 495
           CP  ++ S         L CTCGEE+   +W W+      S  L   N  + V+FH  YS
Sbjct: 84  CPAQTELSSDAQISPYTLSCTCGEEEQGCDWVWDEEDKSSSVSLSCWN--RTVSFHSEYS 141

Query: 496 SGTA 507
            GTA
Sbjct: 142 CGTA 145


>UniRef50_Q4S4U4 Cluster: Chromosome 2 SCAF14738, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2
           SCAF14738, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 349

 Score = 74.5 bits (175), Expect = 3e-12
 Identities = 30/71 (42%), Positives = 49/71 (69%)
 Frame = +3

Query: 498 GYCRVRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEES 677
           G   +RG   +    H+ WE+KM +  YGTD+++G+G+++VN+   ++ F SL+G DE S
Sbjct: 136 GTAAIRGTKELADGQHF-WEVKMTSPVYGTDMMVGIGTSEVNLEKFKYNFGSLLGHDEAS 194

Query: 678 YGLSYTGAVRH 710
           +GLSYTG ++H
Sbjct: 195 WGLSYTGYLQH 205



 Score = 37.1 bits (82), Expect = 0.51
 Identities = 18/45 (40%), Positives = 26/45 (57%)
 Frame = +1

Query: 373 CTCGEEQNLKEWSWERPPYVGSSWLVLTNDLKQVTFHPFYSSGTA 507
           C CGE+    +W W+   +  SS   L+   ++V+FH  YSSGTA
Sbjct: 96  CFCGEDDQGLDWEWDT--HFKSSGAFLSCGNRKVSFHLDYSSGTA 138


>UniRef50_Q6PJ21 Cluster: SPRY domain-containing SOCS box protein 3;
           n=27; Eumetazoa|Rep: SPRY domain-containing SOCS box
           protein 3 - Homo sapiens (Human)
          Length = 355

 Score = 74.1 bits (174), Expect = 4e-12
 Identities = 31/71 (43%), Positives = 49/71 (69%)
 Frame = +3

Query: 498 GYCRVRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEES 677
           G   +RG   +    H+ WEIKM +  YGTD+++G+G++ V++   + TF SL+G+DE+S
Sbjct: 134 GTAAIRGTKELGEGQHF-WEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDS 192

Query: 678 YGLSYTGAVRH 710
           +GLSYTG + H
Sbjct: 193 WGLSYTGLLHH 203



 Score = 38.3 bits (85), Expect = 0.22
 Identities = 19/45 (42%), Positives = 26/45 (57%)
 Frame = +1

Query: 373 CTCGEEQNLKEWSWERPPYVGSSWLVLTNDLKQVTFHPFYSSGTA 507
           C CGEE    +W W+      SS  +L+ D ++V+FH  YS GTA
Sbjct: 94  CRCGEEDEYFDWVWD--DLNKSSATLLSCDNRKVSFHMEYSCGTA 136


>UniRef50_UPI00005A11CE Cluster: PREDICTED: similar to SPRY
           domain-containing SOCS box protein SSB-3; n=1; Canis
           lupus familiaris|Rep: PREDICTED: similar to SPRY
           domain-containing SOCS box protein SSB-3 - Canis
           familiaris
          Length = 406

 Score = 73.7 bits (173), Expect = 5e-12
 Identities = 31/71 (43%), Positives = 48/71 (67%)
 Frame = +3

Query: 498 GYCRVRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEES 677
           G   +RG   +    H+ WEIKM +  YGTD+++G+G++ V++     TF SL+G+DE+S
Sbjct: 162 GTAAIRGTKELGEGQHF-WEIKMTSPVYGTDMMVGIGTSDVDLDKYHHTFCSLLGRDEDS 220

Query: 678 YGLSYTGAVRH 710
           +GLSYTG + H
Sbjct: 221 WGLSYTGLLHH 231


>UniRef50_UPI0000F1E77D Cluster: PREDICTED: similar to conserved
           hypothetical protein; n=1; Danio rerio|Rep: PREDICTED:
           similar to conserved hypothetical protein - Danio rerio
          Length = 163

 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 31/77 (40%), Positives = 42/77 (54%)
 Frame = +3

Query: 498 GYCRVRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEES 677
           G   VRG     H  HY WEI+ L   YG+ +++GVG+    +     TF +LIG D ES
Sbjct: 45  GTAGVRGTKGFTHGEHY-WEIEFLEPPYGSSVMVGVGTQNALLHTGDQTFVNLIGMDSES 103

Query: 678 YGLSYTGAVRHNS*SHQ 728
           +GLSY G + H   S +
Sbjct: 104 WGLSYKGYIWHKGRSRK 120


>UniRef50_Q9VUW0 Cluster: CG10516-PA; n=1; Drosophila
           melanogaster|Rep: CG10516-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 342

 Score = 64.1 bits (149), Expect = 4e-09
 Identities = 25/71 (35%), Positives = 45/71 (63%)
 Frame = +3

Query: 498 GYCRVRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEES 677
           G   VRG   +  N  ++WE++++T   GTD++ G+G+  VN+   +F F S +G + +S
Sbjct: 77  GTAIVRGEQALKTNMVHFWEMRVITTLAGTDVMFGIGTESVNLGQFKFHFVSALGTNAQS 136

Query: 678 YGLSYTGAVRH 710
           +G SY+G ++H
Sbjct: 137 WGFSYSGRIQH 147



 Score = 35.1 bits (77), Expect = 2.1
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = +1

Query: 331 SKRSGPVPWKNLNLCTCGEEQ--NLKEWSWERPPYVGSSWLVLTNDLKQVTFHPFYSSGT 504
           +   G +P  +L  C CGE++  N+  W W        S  V+T+  + + FHP YS GT
Sbjct: 26  TNHKGHIP--DLVRCQCGEDESGNVNAWRWHA---TDESDAVVTD--RDIIFHPTYSQGT 78

Query: 505 A 507
           A
Sbjct: 79  A 79


>UniRef50_A7RJX3 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 268

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 29/71 (40%), Positives = 42/71 (59%)
 Frame = +3

Query: 498 GYCRVRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEES 677
           G   V GN    H  HY WEIK LTD  GT ++IGV +    +    + + +L+G+D+ES
Sbjct: 77  GTAAVLGNKAFAHGQHY-WEIK-LTDVRGTSMMIGVATQDAMLHTDNYEYVNLVGRDQES 134

Query: 678 YGLSYTGAVRH 710
           +GLS+ G + H
Sbjct: 135 WGLSHRGEIWH 145


>UniRef50_Q9VMV3 Cluster: CG14041-PA, isoform A; n=8; Coelomata|Rep:
           CG14041-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 301

 Score = 44.8 bits (101), Expect = 0.003
 Identities = 17/60 (28%), Positives = 35/60 (58%)
 Frame = +3

Query: 531 IHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEESYGLSYTGAVRH 710
           ++N  +YWE+ +    +GT I+ G+G+    +      F +++G++E  +GLS+ G + H
Sbjct: 105 LNNGRHYWELHVSQRVFGTSIMFGIGTKSARLH--ANAFRNMLGENEHGWGLSHKGVLWH 162


>UniRef50_A7M6E3 Cluster: F-box/SPRY-domain protein 1; n=1; Dugesia
           ryukyuensis|Rep: F-box/SPRY-domain protein 1 - Dugesia
           ryukyuensis
          Length = 352

 Score = 35.9 bits (79), Expect = 1.2
 Identities = 20/66 (30%), Positives = 31/66 (46%)
 Frame = +3

Query: 510 VRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEESYGLS 689
           +RGN       H  WEI       GT  ++GV + K  +   Q  + SL+G D+ES+G  
Sbjct: 126 IRGNRGYSEGIHI-WEINWPLTMRGTHAVVGVSTEKCQLQ--QDRYVSLVGIDDESWGWD 182

Query: 690 YTGAVR 707
               ++
Sbjct: 183 IVNRIK 188


>UniRef50_Q61CY5 Cluster: Putative uncharacterized protein CBG12711;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG12711 - Caenorhabditis
           briggsae
          Length = 249

 Score = 34.7 bits (76), Expect = 2.7
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 10/58 (17%)
 Frame = +1

Query: 247 CREYATMES--NNRKQVNSKY------QARPYCPCWSKRSGPVPWKNLNLCT--CGEE 390
           C+++   E   N  +Q+  KY      + R Y   W +R+GP PW+   +C    GEE
Sbjct: 134 CKDHDKFEEAMNKERQIGKKYRDDYLEECRKYTNNWEERNGPFPWRVCEICAFKFGEE 191


>UniRef50_Q965N6 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 466

 Score = 33.1 bits (72), Expect = 8.4
 Identities = 20/72 (27%), Positives = 32/72 (44%)
 Frame = +3

Query: 510 VRGNCPMIHNYHYYWEIKMLTDTYGTDILIGVGSNKVNISDPQFTFTSLIGQDEESYGLS 689
           +RG       +H  W+I+      GT  ++GV +    +    +T  +LIG  +ESYG  
Sbjct: 147 IRGKMGYSRGFHV-WQIEWPERQRGTHAVVGVATKNAPLHAAGYT--ALIGTTDESYGWD 203

Query: 690 YTGAVRHNS*SH 725
            T    H+   H
Sbjct: 204 ITRRECHHDSKH 215


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 783,536,274
Number of Sequences: 1657284
Number of extensions: 15642706
Number of successful extensions: 38850
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 37461
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38835
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 68731504465
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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