Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NRPG0009
(700 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B4A0E Cluster: PREDICTED: similar to proteasome... 274 2e-72
UniRef50_UPI00003C07D6 Cluster: PREDICTED: similar to Proteasome... 256 5e-67
UniRef50_P28070 Cluster: Proteasome subunit beta type-4 precurso... 222 6e-57
UniRef50_Q7QLL8 Cluster: Proteasome subunit beta type; n=4; Endo... 208 1e-52
UniRef50_Q9VNA5 Cluster: Probable proteasome subunit beta type-4... 193 3e-48
UniRef50_Q5DAM2 Cluster: Proteasome subunit beta type; n=1; Schi... 172 8e-42
UniRef50_Q4P203 Cluster: Proteasome subunit beta type; n=1; Usti... 164 2e-39
UniRef50_Q556Q0 Cluster: Proteasome subunit beta type; n=2; Dict... 155 1e-36
UniRef50_Q0UWV2 Cluster: Predicted protein; n=4; Pezizomycotina|... 149 5e-35
UniRef50_Q5K974 Cluster: Proteasome subunit beta type; n=1; Filo... 141 2e-32
UniRef50_Q9USQ9 Cluster: Probable proteasome subunit beta type-4... 140 4e-32
UniRef50_P30657 Cluster: Proteasome component PRE4; n=13; Saccha... 137 3e-31
UniRef50_Q018W2 Cluster: Proteasome subunit beta type; n=2; Ostr... 133 3e-30
UniRef50_Q7DLR9 Cluster: Proteasome subunit beta type-4 precurso... 132 8e-30
UniRef50_UPI0000499BD3 Cluster: proteasome beta subunit; n=2; En... 127 3e-28
UniRef50_P90868 Cluster: Putative uncharacterized protein pbs-7;... 121 2e-26
UniRef50_Q8I6Y3 Cluster: Proteasome subunit beta type; n=8; Tryp... 115 1e-24
UniRef50_UPI00006CF83A Cluster: Proteasome A-type and B-type fam... 110 4e-23
UniRef50_A2F3X4 Cluster: Family T1, proteasome beta subunit, thr... 99 9e-20
UniRef50_Q4MZR6 Cluster: 20S proteasome beta 7 subunit, putative... 96 6e-19
UniRef50_Q8SS01 Cluster: 26S PROTEASOME BETA-TYPE SUBUNIT; n=1; ... 96 6e-19
UniRef50_A7AVH7 Cluster: Proteasome subunit beta type 4; n=1; Ba... 94 3e-18
UniRef50_Q6BG89 Cluster: Proteasome subunit beta type; n=3; Para... 94 3e-18
UniRef50_Q7R5Z3 Cluster: GLP_81_66910_67563; n=1; Giardia lambli... 92 1e-17
UniRef50_Q9U570 Cluster: Proteasome subunit beta type; n=6; Plas... 89 7e-17
UniRef50_Q5CRD6 Cluster: Proteasome subunit beta7; NTN hydrolase... 69 1e-10
UniRef50_Q8TW10 Cluster: Protease subunit of the proteasome; n=2... 62 1e-08
UniRef50_Q8SRH6 Cluster: 20S PROTEASOME ALPHA-TYPE SUBUNIT; n=1;... 59 1e-07
UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum... 58 2e-07
UniRef50_Q980L4 Cluster: Proteasome subunit; n=4; Sulfolobaceae|... 56 1e-06
UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2; Desulfuro... 56 1e-06
UniRef50_P20618 Cluster: Proteasome subunit beta type-1 precurso... 54 3e-06
UniRef50_Q9IB84 Cluster: Proteasome subunit beta type-1-A; n=14;... 53 6e-06
UniRef50_A5UM14 Cluster: Proteasome, beta subunit; n=1; Methanob... 53 8e-06
UniRef50_A0RU86 Cluster: 20S proteasome, alpha and beta subunit;... 52 1e-05
UniRef50_Q8ZST5 Cluster: Proteasome, beta subunit; n=5; Thermopr... 52 2e-05
UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1; ... 51 3e-05
UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; ... 50 4e-05
UniRef50_UPI000150A719 Cluster: Proteasome A-type and B-type fam... 50 5e-05
UniRef50_Q74MP5 Cluster: NEQ203; n=1; Nanoarchaeum equitans|Rep:... 48 2e-04
UniRef50_P25043 Cluster: Proteasome component PUP1 precursor; n=... 46 7e-04
UniRef50_Q6CA23 Cluster: Yarrowia lipolytica chromosome D of str... 46 9e-04
UniRef50_A0BPF5 Cluster: Chromosome undetermined scaffold_12, wh... 45 0.002
UniRef50_Q98S25 Cluster: Proteasome subunit beta type; n=1; Guil... 45 0.002
UniRef50_A5K9H5 Cluster: Proteasome subunit beta type; n=1; Plas... 44 0.003
UniRef50_A4FNF9 Cluster: Diguanylate cyclase/phosphodiesterase w... 44 0.004
UniRef50_A0CN28 Cluster: Proteasome subunit beta type; n=4; Para... 44 0.004
UniRef50_Q7QWS6 Cluster: Proteasome subunit beta type; n=1; Giar... 44 0.005
UniRef50_Q5CUK0 Cluster: Proteasome subunit beta type; n=2; Cryp... 44 0.005
UniRef50_Q1ZXN1 Cluster: Proteasome subunit beta type; n=2; Dict... 43 0.006
UniRef50_Q4YMY0 Cluster: Proteasome subunit beta type; n=5; Plas... 42 0.019
UniRef50_Q6E6B2 Cluster: Proteasome beta-type subunit-like prote... 41 0.034
UniRef50_Q8SQN7 Cluster: Proteasome subunit beta type; n=1; Ence... 40 0.044
UniRef50_Q5AF53 Cluster: Putative uncharacterized protein PRE7; ... 40 0.059
UniRef50_Q9N9W8 Cluster: Proteasome subunit beta type-3; n=2; Gi... 40 0.059
UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Haloba... 40 0.078
UniRef50_Q8SR11 Cluster: Proteasome subunit beta type; n=1; Ence... 39 0.10
UniRef50_UPI00004991C1 Cluster: proteasome beta subunit; n=1; En... 38 0.18
UniRef50_Q98RS2 Cluster: Proteasome subunit beta type; n=1; Guil... 38 0.18
UniRef50_P49721 Cluster: Proteasome subunit beta type-2; n=40; F... 38 0.18
UniRef50_P28072 Cluster: Proteasome subunit beta type-6 precurso... 38 0.24
UniRef50_Q4N2N3 Cluster: Proteasome beat subunit, putative; n=3;... 37 0.41
UniRef50_A2F716 Cluster: Proteasome subunit beta type; n=1; Tric... 37 0.41
UniRef50_P49720 Cluster: Proteasome subunit beta type-3; n=85; E... 37 0.41
UniRef50_Q8T915 Cluster: AT05866p; n=1; Drosophila melanogaster|... 37 0.55
UniRef50_Q8LD27 Cluster: Proteasome subunit beta type-6 precurso... 36 0.72
UniRef50_A1UHS7 Cluster: 20S proteasome, A and B subunits; n=19;... 36 0.96
UniRef50_Q8I0U7 Cluster: Proteasome, putative; n=5; Plasmodium|R... 36 0.96
UniRef50_Q6RKE3 Cluster: Polyketide synthase; n=2; Fungi/Metazoa... 36 0.96
UniRef50_UPI0000DB7B4D Cluster: PREDICTED: similar to Dicer-1 CG... 36 1.3
UniRef50_Q8T8U1 Cluster: Proteasome subunit beta type; n=1; Dros... 36 1.3
UniRef50_UPI0000E47CE3 Cluster: PREDICTED: hypothetical protein;... 35 1.7
UniRef50_Q4UIA0 Cluster: Proteasome subunit beta type; n=8; Acon... 35 1.7
UniRef50_Q1D018 Cluster: Beta-ketoacyl synthase family protein; ... 35 2.2
UniRef50_Q7DLS1 Cluster: Proteasome subunit beta type-7-B precur... 35 2.2
UniRef50_Q4UER7 Cluster: Proteasome subunit y, putative; n=4; Pi... 34 2.9
UniRef50_P40304 Cluster: Proteasome subunit beta type-1 precurso... 34 2.9
UniRef50_P28065 Cluster: Proteasome subunit beta type-9 precurso... 34 3.9
UniRef50_P34286 Cluster: Proteasome subunit beta type-1; n=2; Ca... 34 3.9
UniRef50_Q4RM53 Cluster: Chromosome 10 SCAF15019, whole genome s... 33 6.7
UniRef50_Q2J9Q3 Cluster: 20S proteasome, A and B subunits; n=23;... 33 6.7
UniRef50_UPI0000DD7CB5 Cluster: PREDICTED: hypothetical protein;... 33 8.9
UniRef50_UPI0000D55E14 Cluster: PREDICTED: similar to CG5912-PA;... 33 8.9
UniRef50_A0D0W1 Cluster: Chromosome undetermined scaffold_33, wh... 33 8.9
UniRef50_Q9JMS5 Cluster: Uncharacterized protein yuaO precursor;... 33 8.9
UniRef50_Q99436 Cluster: Proteasome subunit beta type-7 precurso... 33 8.9
>UniRef50_UPI00015B4A0E Cluster: PREDICTED: similar to proteasome
subunit N3; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to proteasome subunit N3 - Nasonia vitripennis
Length = 262
Score = 274 bits (671), Expect = 2e-72
Identities = 124/199 (62%), Positives = 154/199 (77%)
Frame = +1
Query: 76 DTMNPTPLWQNGPSPGAFYNFPGNASTIAPSRHGVQDFTAHSASPITTTTTVIGVKFDKG 255
D +PTP WQNGP+PGA YNFPG T + +G+Q + SP+TT T+VIG++F G
Sbjct: 8 DYFSPTPFWQNGPAPGAIYNFPG--PTASSGTNGMQ----RTQSPMTTGTSVIGLQFKDG 61
Query: 256 CVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERCVGD 435
VIA D L SYGSLARFR+C RV+KVND I+LG GGDYAD+QYL+ II+QKI+DERC+ D
Sbjct: 62 IVIAADVLASYGSLARFRNCERVIKVNDNIILGAGGDYADYQYLRSIIEQKILDERCLDD 121
Query: 436 GLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKLGTAYEDAVISN 615
G LKP+SLHCWLTRV+YNKRSK DPLWN++++ GI+D + FLG VDKLGTA+ D VI+
Sbjct: 122 GFTLKPKSLHCWLTRVMYNKRSKFDPLWNNFIIGGIEDDKLFLGTVDKLGTAFTDPVIAT 181
Query: 616 GLGAYMATPLLRDAVDKGP 672
G GAYMA+PLL A + P
Sbjct: 182 GYGAYMASPLLNKAYEANP 200
>UniRef50_UPI00003C07D6 Cluster: PREDICTED: similar to Proteasome
subunit beta type 4 precursor (Proteasome beta chain)
(Macropain beta chain) (Multicatalytic endopeptidase
complex beta chain) (Proteasome chain 3); n=1; Apis
mellifera|Rep: PREDICTED: similar to Proteasome subunit
beta type 4 precursor (Proteasome beta chain) (Macropain
beta chain) (Multicatalytic endopeptidase complex beta
chain) (Proteasome chain 3) - Apis mellifera
Length = 256
Score = 256 bits (626), Expect = 5e-67
Identities = 118/207 (57%), Positives = 154/207 (74%), Gaps = 1/207 (0%)
Frame = +1
Query: 76 DTMNPTPLWQNGPSPGAFYNFPGNASTIAPSRHGVQDFTAHSASPITTTTTVIGVKFDKG 255
D P PLWQNGP PGAFY+FPGN++ G Q S +P+TT T+V+G++F G
Sbjct: 7 DWQTPAPLWQNGPVPGAFYHFPGNSTHFKVG--GYQ----RSQAPMTTGTSVVGIQFKNG 60
Query: 256 CVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERCVGD 435
+IA D LGSYGSLAR+R+ RVMKVND I+LG GGDYAD+Q LK I++KI++E C+ D
Sbjct: 61 ILIATDILGSYGSLARYRNLERVMKVNDNIILGAGGDYADYQCLKSHIERKILEEECLDD 120
Query: 436 GLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKLGTAYEDAVISN 615
GL LKP++LHCWLTRVLYN+RS+ DP WN++++ G++ + FLG VDKLGTAY D VI+
Sbjct: 121 GLSLKPKALHCWLTRVLYNRRSQFDPFWNNFIIGGLEGDKLFLGTVDKLGTAYSDPVIAT 180
Query: 616 GLGAYMATPLLRDAVDKG-PLDQETAI 693
G GAYMATP+LR A ++ + +E AI
Sbjct: 181 GYGAYMATPILRKAYEENKEMSKEQAI 207
>UniRef50_P28070 Cluster: Proteasome subunit beta type-4 precursor;
n=40; Eumetazoa|Rep: Proteasome subunit beta type-4
precursor - Homo sapiens (Human)
Length = 264
Score = 222 bits (543), Expect = 6e-57
Identities = 104/209 (49%), Positives = 140/209 (66%), Gaps = 1/209 (0%)
Frame = +1
Query: 64 AFMGDTMNPTPLWQNGPSPGAFYNFPGNA-STIAPSRHGVQDFTAHSASPITTTTTVIGV 240
AF+G LW GP+PG FY P S + P+ + + +P+ T T+V+GV
Sbjct: 3 AFLGSRSG---LWAGGPAPGQFYRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGV 59
Query: 241 KFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDE 420
KF+ G VIA D LGSYGSLARFR+ R+M+VN+ +LG GDYADFQYLK ++ Q +IDE
Sbjct: 60 KFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDE 119
Query: 421 RCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKLGTAYED 600
+GDG PR++H WLTR +Y++RSKM+PLWN+ V+ G DGE FLG VD LG AYE
Sbjct: 120 ELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEA 179
Query: 601 AVISNGLGAYMATPLLRDAVDKGPLDQET 687
++ G GAY+A PLLR+ ++K P+ +T
Sbjct: 180 PSLATGYGAYLAQPLLREVLEKQPVLSQT 208
>UniRef50_Q7QLL8 Cluster: Proteasome subunit beta type; n=4;
Endopterygota|Rep: Proteasome subunit beta type -
Anopheles gambiae str. PEST
Length = 271
Score = 208 bits (507), Expect = 1e-52
Identities = 97/191 (50%), Positives = 131/191 (68%), Gaps = 4/191 (2%)
Frame = +1
Query: 94 PLWQNGPSPGAFYNFPGNA----STIAPSRHGVQDFTAHSASPITTTTTVIGVKFDKGCV 261
P W NGP+PGAFYNFPG+ + A S + T S P+TT T+V+G+ F G +
Sbjct: 12 PFWSNGPAPGAFYNFPGSTVAGGAMQARSETPGEFGTQRSYYPVTTGTSVVGLMFKDGVI 71
Query: 262 IAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERCVGDGL 441
IA D L SYGSLARF D RV ++ND +LG GGD+ADFQY+K I QK+ID++C+ D
Sbjct: 72 IAADKLISYGSLARFHDVDRVYRINDKTVLGIGGDFADFQYIKRHIDQKVIDDQCLDDKN 131
Query: 442 QLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKLGTAYEDAVISNGL 621
++KPRS + WLTRV+YN+RS+ PL+ V+ G+QDGEPFLG V+ G +Y V++ G
Sbjct: 132 EMKPRSFYNWLTRVMYNRRSEFQPLYLDLVIGGMQDGEPFLGHVNLRGRSYTSNVVATGY 191
Query: 622 GAYMATPLLRD 654
G ++A PLLR+
Sbjct: 192 GTHLALPLLRE 202
>UniRef50_Q9VNA5 Cluster: Probable proteasome subunit beta type-4;
n=3; Sophophora|Rep: Probable proteasome subunit beta
type-4 - Drosophila melanogaster (Fruit fly)
Length = 268
Score = 193 bits (471), Expect = 3e-48
Identities = 93/206 (45%), Positives = 138/206 (66%), Gaps = 6/206 (2%)
Frame = +1
Query: 94 PLWQNGPSPGAFYNFPGNASTIAPSRHGVQDF----TAHSASPITTTTTVIGVKFDKGCV 261
P+WQNGP+PG FYNF G + + + T HS + TT T+V+G+++D G +
Sbjct: 11 PMWQNGPAPGEFYNFTGGQTPVQQLPRELTTMGPYGTKHSTASSTTGTSVLGIRYDSGVM 70
Query: 262 IAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERCVGDGL 441
+A DTL SYGS+AR+++ RV KVN ILLG GD+AD Q +K I QK+I+++C D +
Sbjct: 71 LAADTLVSYGSMARYQNIERVFKVNKNILLGGSGDFADIQSIKRNIDQKMIEDQCCDDNI 130
Query: 442 QLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI-QDGEPFLGAVDKLGTAYEDAVISNG 618
++KP+SL W+TRVLYN+RS+M+PL+ VV G+ +G P+L VD G +YED V++ G
Sbjct: 131 EMKPKSLASWMTRVLYNRRSRMNPLYIDVVVGGVDNEGTPYLANVDLRGRSYEDYVVATG 190
Query: 619 LGAYMATPLLRDAVDKGPLDQE-TAI 693
++A PL+R +K P D++ TA+
Sbjct: 191 FARHLAVPLVR---EKKPKDRDFTAV 213
>UniRef50_Q5DAM2 Cluster: Proteasome subunit beta type; n=1;
Schistosoma japonicum|Rep: Proteasome subunit beta type
- Schistosoma japonicum (Blood fluke)
Length = 248
Score = 172 bits (418), Expect = 8e-42
Identities = 72/157 (45%), Positives = 114/157 (72%), Gaps = 1/157 (0%)
Frame = +1
Query: 196 HSASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYAD 375
H+ +PI T T+VIG+K+ G V+A D L SYGSLA++ D R+ KVN+ ++ C GD AD
Sbjct: 22 HTMTPICTGTSVIGIKYKDGVVLAADLLVSYGSLAKYMDFERMFKVNESTVMCCSGDVAD 81
Query: 376 FQYLKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQ-DG 552
FQ+LK +++ + + DG +L P +LH W+TR+LYN+RS+++PLWN+Y+V GI+ +G
Sbjct: 82 FQFLKHHVKELTHVDNLLSDGFKLSPHALHSWITRILYNRRSRLEPLWNTYLVGGIEANG 141
Query: 553 EPFLGAVDKLGTAYEDAVISNGLGAYMATPLLRDAVD 663
EPF+G + LG ++ + ++ G GAY+ATP+LR+ ++
Sbjct: 142 EPFIGYCNMLGVSFSENYVATGFGAYLATPILRECLE 178
>UniRef50_Q4P203 Cluster: Proteasome subunit beta type; n=1;
Ustilago maydis|Rep: Proteasome subunit beta type -
Ustilago maydis (Smut fungus)
Length = 266
Score = 164 bits (398), Expect = 2e-39
Identities = 79/195 (40%), Positives = 120/195 (61%), Gaps = 2/195 (1%)
Frame = +1
Query: 85 NPTPLWQNGPSPGAFYNFPGNASTIAPSRHGVQDFTAHSASPITTTTTVIGVKFDKGCVI 264
+P W + P+ A+ N G S + D T+H++ PI T T+V+G+K+ G ++
Sbjct: 5 HPGQSWSSQPNQ-AYVNM-GTPSFSTAAASSSSDPTSHTSQPIVTGTSVLGIKYKDGIML 62
Query: 265 AGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERCVGDGLQ 444
A DTL SYGSLARF D R+ + L+G GD +D+QY++ ++ + I E DG
Sbjct: 63 ATDTLASYGSLARFMDITRISQFGQNTLIGASGDMSDWQYVQHMLNKLITSEDVAADGHN 122
Query: 445 LKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI--QDGEPFLGAVDKLGTAYEDAVISNG 618
L P ++ +L RV+Y +RSK++PLWNS+V+ G+ +DG PFLG VD LGT + + I+ G
Sbjct: 123 LTPTQIYAYLARVMYQRRSKINPLWNSFVLGGVDPKDGTPFLGYVDLLGTTFTSSTIATG 182
Query: 619 LGAYMATPLLRDAVD 663
G ++A PLLR V+
Sbjct: 183 FGLHLAQPLLRKMVE 197
>UniRef50_Q556Q0 Cluster: Proteasome subunit beta type; n=2;
Dictyostelium discoideum|Rep: Proteasome subunit beta
type - Dictyostelium discoideum AX4
Length = 259
Score = 155 bits (376), Expect = 1e-36
Identities = 70/155 (45%), Positives = 102/155 (65%)
Frame = +1
Query: 208 PITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYL 387
PI T T+VI +K+DKG V+ D L SYGSLARF R+ K ++G G+Y+DFQ +
Sbjct: 40 PIVTGTSVIAIKYDKGVVMGSDMLLSYGSLARFNSTERMKKFGGYTIVGASGEYSDFQSI 99
Query: 388 KDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLG 567
+ + + D+ C+ DG +L + +L RVLYN+R++ +PLWN+ VV G Q G+ FLG
Sbjct: 100 TNTLNDLVTDDHCMDDGSKLSSEEIWNYLARVLYNQRNRGNPLWNTLVVMGYQGGKSFLG 159
Query: 568 AVDKLGTAYEDAVISNGLGAYMATPLLRDAVDKGP 672
VD +GT Y+D +I+ G G+++A PLLR A D+ P
Sbjct: 160 KVDLVGTCYKDDIITTGYGSHIALPLLRKARDENP 194
>UniRef50_Q0UWV2 Cluster: Predicted protein; n=4;
Pezizomycotina|Rep: Predicted protein - Phaeosphaeria
nodorum (Septoria nodorum)
Length = 260
Score = 149 bits (362), Expect = 5e-35
Identities = 76/178 (42%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
Frame = +1
Query: 163 PSRHGVQDFTAHSASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDL 342
PS H+ SPI T T+V+ KF G VIA D L SYGSLARF D R+ K ND
Sbjct: 21 PSHFQTAGPNQHTQSPIVTGTSVLAAKFKDGVVIAADNLASYGSLARFTDVKRLRKFNDE 80
Query: 343 ILLGCGGDYADFQYLKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWN 522
+++G GGD +D QYL ++ I E + L ++LH +L +V+YN+RSK DPLWN
Sbjct: 81 VVVGFGGDVSDMQYLDRLLNSLDIRETYSSNETALNAKNLHTYLAKVMYNRRSKFDPLWN 140
Query: 523 SYVVAGIQDGE--PFLGAVDKLGTAYEDAVISNGLGAYMATPLLRDAV-DKGPLDQET 687
++AG+ DGE PFL + D LGT + ++ G GA++A P+LR + D+ +++ T
Sbjct: 141 HLLIAGM-DGESKPFLASADLLGTTFSSPSLATGFGAHLAQPILRTILPDEASVEKVT 197
>UniRef50_Q5K974 Cluster: Proteasome subunit beta type; n=1;
Filobasidiella neoformans|Rep: Proteasome subunit beta
type - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 280
Score = 141 bits (341), Expect = 2e-32
Identities = 83/203 (40%), Positives = 116/203 (57%), Gaps = 10/203 (4%)
Frame = +1
Query: 85 NPTPLW-QNGPSPGAF--YN-FP-GNASTIAPSRHGVQDFTAHSASPITTTTTVIGVKFD 249
N LW Q P+ AF YN FP G S H +H+ P+ T T+V+G+KFD
Sbjct: 5 NHPALWKQPAPANSAFNDYNTFPLGQTQRHNTSSH--HGPMSHTQQPLVTGTSVLGIKFD 62
Query: 250 KGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERCV 429
KG +IA D LGSYGSLARFRD R+ + LLG GD +D+Q+LK + + +E +
Sbjct: 63 KGVMIAADNLGSYGSLARFRDIQRLHPLGKHTLLGVAGDMSDYQWLKRELDGLLREESAL 122
Query: 430 G---DGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQD--GEPFLGAVDKLGTAY 594
L P +++ L+ + Y +RSK+DP+WN+ +V G D E FL VD LGT Y
Sbjct: 123 SLTDSHPSLSPSNIYTLLSNLFYARRSKVDPIWNAVLVGGWDDTKKESFLAYVDLLGTTY 182
Query: 595 EDAVISNGLGAYMATPLLRDAVD 663
++ G GA++A PLLR+A +
Sbjct: 183 SAPTLATGFGAHLAQPLLREAYE 205
>UniRef50_Q9USQ9 Cluster: Probable proteasome subunit beta type-4;
n=17; Ascomycota|Rep: Probable proteasome subunit beta
type-4 - Schizosaccharomyces pombe (Fission yeast)
Length = 262
Score = 140 bits (338), Expect = 4e-32
Identities = 65/157 (41%), Positives = 100/157 (63%), Gaps = 2/157 (1%)
Frame = +1
Query: 199 SASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADF 378
+ PI T ++V+ +KF G +IA D L SYGSLARF D R+ KV D ++G GGD +D+
Sbjct: 36 TVQPIVTGSSVLALKFADGVMIAADNLASYGSLARFYDVERLTKVGDNTIVGAGGDISDY 95
Query: 379 QYLKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI--QDG 552
Q ++ ++++ I E GDG L+P +H +L++VLY +R+K+DP WN +VAG+ ++
Sbjct: 96 QQIQRLLEKLEIKEGNYGDGYALQPSYIHEYLSKVLYARRNKLDPYWNQLIVAGVDGENK 155
Query: 553 EPFLGAVDKLGTAYEDAVISNGLGAYMATPLLRDAVD 663
EP++ D GT Y I+ G ++A P+LR A D
Sbjct: 156 EPYVAFADLRGTTYSAPAIATGFAMHLALPMLRKATD 192
>UniRef50_P30657 Cluster: Proteasome component PRE4; n=13;
Saccharomycetales|Rep: Proteasome component PRE4 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 266
Score = 137 bits (331), Expect = 3e-31
Identities = 70/173 (40%), Positives = 103/173 (59%), Gaps = 5/173 (2%)
Frame = +1
Query: 196 HSASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYAD 375
++ PI T T+VI +K+D G +IA D LGSYGSL RF R++ V D ++G GD +D
Sbjct: 33 NTQQPIVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISD 92
Query: 376 FQY----LKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI 543
Q+ LKD++ + D L+P + +L V+Y +RSKM+PLWN+ +VAG+
Sbjct: 93 MQHIERLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGV 152
Query: 544 Q-DGEPFLGAVDKLGTAYEDAVISNGLGAYMATPLLRDAVDKGPLDQETAIAV 699
Q +G+ FL V+ LG Y ++ G GA+MA PLLR VD+ +T + V
Sbjct: 153 QSNGDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQV 205
>UniRef50_Q018W2 Cluster: Proteasome subunit beta type; n=2;
Ostreococcus|Rep: Proteasome subunit beta type -
Ostreococcus tauri
Length = 289
Score = 133 bits (322), Expect = 3e-30
Identities = 64/166 (38%), Positives = 100/166 (60%), Gaps = 1/166 (0%)
Frame = +1
Query: 205 SPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQY 384
+P T T+ +G+K+ G ++A DTL YGS R++ RV +VND + G+ +DF Y
Sbjct: 68 TPYVTGTSALGLKYAGGVLLATDTLACYGSTKRYKSVERVKRVNDKCAIAFTGELSDFAY 127
Query: 385 LKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQ-DGEPF 561
+ D++++ ++ C DG ++ +LTRV+YN+RSK DPLWNS+VVAG GE F
Sbjct: 128 VCDLLEELTTEDFCEDDGTTRDAEEIYQYLTRVMYNRRSKFDPLWNSFVVAGYDAKGEAF 187
Query: 562 LGAVDKLGTAYEDAVISNGLGAYMATPLLRDAVDKGPLDQETAIAV 699
G V +GT Y D ++ G G ++A P+ R+ K L +E A+ +
Sbjct: 188 CGTVGMIGTHYADDHVAAGFGNHIARPIFREFY-KPDLTEEEAVEI 232
>UniRef50_Q7DLR9 Cluster: Proteasome subunit beta type-4 precursor;
n=8; Magnoliophyta|Rep: Proteasome subunit beta type-4
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 246
Score = 132 bits (319), Expect = 8e-30
Identities = 55/149 (36%), Positives = 96/149 (64%)
Frame = +1
Query: 208 PITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYL 387
P T T+++ +K+ G ++A D GSYGS R+++ RV + LLG G+ +DFQ +
Sbjct: 27 PYVTGTSIVAIKYKDGVLMASDMGGSYGSTLRYKNIERVKAIGKHSLLGASGEISDFQEI 86
Query: 388 KDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLG 567
+ + +++ DG L P+ +H +LTRV+YN+R+K +PLWN+ V+ G+++G+ +LG
Sbjct: 87 LRYLDELTLNDNMWDDGNSLGPKEIHNYLTRVMYNRRNKFNPLWNTLVLGGVKNGKSYLG 146
Query: 568 AVDKLGTAYEDAVISNGLGAYMATPLLRD 654
V +G ++ED ++ G G ++A P+LRD
Sbjct: 147 MVSMIGVSFEDDHVATGFGNHLARPILRD 175
>UniRef50_UPI0000499BD3 Cluster: proteasome beta subunit; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome beta
subunit - Entamoeba histolytica HM-1:IMSS
Length = 225
Score = 127 bits (306), Expect = 3e-28
Identities = 60/151 (39%), Positives = 95/151 (62%), Gaps = 1/151 (0%)
Frame = +1
Query: 202 ASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQ 381
A + T +V+G+K++ G +IA DTLGSYGS+A F+D RV+K+ ++ G+Y+DF
Sbjct: 13 AEVVLGTASVLGIKYEGGVLIAADTLGSYGSMALFKDLERVIKLGKYTIIAGSGEYSDFI 72
Query: 382 YLKDIIQQKII-DERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEP 558
L + +Q+K+ DE C G KP L+ + R+LY R PL+ + +V G++ E
Sbjct: 73 ELNETLQKKVNGDECCEGKENGYKPSELYSYAQRILYKHRCDQKPLFVTLIVGGVKKDEI 132
Query: 559 FLGAVDKLGTAYEDAVISNGLGAYMATPLLR 651
FLG D GT++ + +++G+GA+MA PLLR
Sbjct: 133 FLGQTDMYGTSFTENYVASGIGAHMAMPLLR 163
>UniRef50_P90868 Cluster: Putative uncharacterized protein pbs-7;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein pbs-7 - Caenorhabditis elegans
Length = 236
Score = 121 bits (291), Expect = 2e-26
Identities = 65/182 (35%), Positives = 110/182 (60%), Gaps = 10/182 (5%)
Frame = +1
Query: 184 DFTAHSASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGG 363
D + +P T T+VI +++ G V+ D + SYG +AR+++ R KVND +L+ GG
Sbjct: 5 DEVQRTLNPTCTGTSVIALQYKTGVVVLTDRVVSYGKMARYKNVSRQYKVNDNVLIAFGG 64
Query: 364 DYADFQYLKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI 543
D+ADF +L+++I+++++ + + P++LH +LT +LY KR KM+P+WN+ VVAG+
Sbjct: 65 DHADFHWLQNVIERQVLLWKRFDQ--DIGPKALHGYLTSLLYAKRCKMNPVWNTLVVAGV 122
Query: 544 QDGE--------PFLGAVDKLGTAYEDAVISNGLGAYMATPLLRDAVDK--GPLDQETAI 693
++ E PF+G + + G AY+ I+ GLGA++ + D K L +E A
Sbjct: 123 EEEEKNNKETSTPFIGVITQKGCAYQVKHIATGLGAFLLNQAVEDEWRKKGEDLSREEAE 182
Query: 694 AV 699
AV
Sbjct: 183 AV 184
>UniRef50_Q8I6Y3 Cluster: Proteasome subunit beta type; n=8;
Trypanosomatidae|Rep: Proteasome subunit beta type -
Leishmania major
Length = 220
Score = 115 bits (277), Expect = 1e-24
Identities = 60/158 (37%), Positives = 91/158 (57%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
+VI +K++ G ++A DTL SYGSLA++ + PR+ + + G YADFQ + ++
Sbjct: 6 SVIAIKYNGGVLMAADTLLSYGSLAKWPNIPRIKLLGSHSAVCATGSYADFQMMAKQVED 65
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKLG 585
I +R + +L P + +L R +Y KR +P V G++D E FL AVD +G
Sbjct: 66 NIERQRMYYNVDELNPSEVFSYLHRSIYQKRCDFEPCLCQMVFIGVRDSETFLAAVDDVG 125
Query: 586 TAYEDAVISNGLGAYMATPLLRDAVDKGPLDQETAIAV 699
T +ED ++ G GAY+A PLLR A++K P A AV
Sbjct: 126 TRWEDDCVATGYGAYIALPLLRQALEKNPGGLSRAQAV 163
>UniRef50_UPI00006CF83A Cluster: Proteasome A-type and B-type family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Proteasome A-type and B-type family protein -
Tetrahymena thermophila SB210
Length = 289
Score = 110 bits (264), Expect = 4e-23
Identities = 52/150 (34%), Positives = 86/150 (57%)
Frame = +1
Query: 196 HSASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYAD 375
H+ +PITT ++VIG+ F+ G +IA DT SYG ++R+ RV K+ D G+++D
Sbjct: 66 HTLNPITTGSSVIGIAFNGGVIIASDTSISYGGMSRYNHIQRVHKITDNCAFASSGEFSD 125
Query: 376 FQYLKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGE 555
FQ L +I + D + PR +++++ Y+ R+KM+PL+ V+ G+ +G+
Sbjct: 126 FQELSRLIDEMTNQTYLNDDKINYTPRDYGNYISQLQYHHRNKMNPLYLWNVIGGVDNGK 185
Query: 556 PFLGAVDKLGTAYEDAVISNGLGAYMATPL 645
P+L +D GT E +S G G Y+ PL
Sbjct: 186 PYLAHIDLYGTYIETNHVSTGFGNYLCGPL 215
>UniRef50_A2F3X4 Cluster: Family T1, proteasome beta subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome beta subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 214
Score = 99.1 bits (236), Expect = 9e-20
Identities = 50/152 (32%), Positives = 82/152 (53%), Gaps = 1/152 (0%)
Frame = +1
Query: 211 ITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLK 390
IT + ++ K+D G ++A D +YGS+ R + ++V I++G G++ADFQ L
Sbjct: 4 ITASGAIVAAKYDGGILLASDLSITYGSMFRHNNVSHFVEVAPNIIIGASGEFADFQTLI 63
Query: 391 DIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQ-DGEPFLG 567
++I+ I+ ++C +G L +H ++ R +Y RS M PL +VAGI DG FL
Sbjct: 64 EVIKSVILQQQCKHNGEYLTASEVHNYIKRYMYQCRSNMKPLSCKVIVAGINPDGSKFLA 123
Query: 568 AVDKLGTAYEDAVISNGLGAYMATPLLRDAVD 663
D G ++E I G G Y+ + D V+
Sbjct: 124 CTDPYGASWESDHIGTGFGKYLQGLQIADVVN 155
>UniRef50_Q4MZR6 Cluster: 20S proteasome beta 7 subunit, putative;
n=2; Theileria|Rep: 20S proteasome beta 7 subunit,
putative - Theileria parva
Length = 229
Score = 96.3 bits (229), Expect = 6e-19
Identities = 52/150 (34%), Positives = 82/150 (54%), Gaps = 4/150 (2%)
Frame = +1
Query: 217 TTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYL--- 387
T ++I +K+++G ++ DT S G +AR+ + R+ V+ L GD AD QYL
Sbjct: 6 TGASIIAMKYNEGVLMMTDTKWSLGRMARYMNVLRLESVSSNTLFATSGDAADHQYLTRV 65
Query: 388 -KDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFL 564
K + +++ L P L + +R+LY++R+K+DP+ S VV G+ +G+PFL
Sbjct: 66 LKHAVHTDLLEHNNDASKALLNPEMLLNYTSRLLYHRRTKLDPVLVSAVVGGLSNGKPFL 125
Query: 565 GAVDKLGTAYEDAVISNGLGAYMATPLLRD 654
G D GT Y D + GLG Y A LR+
Sbjct: 126 GYTDYYGTKYTDNFVVTGLGKYFAIGPLRE 155
>UniRef50_Q8SS01 Cluster: 26S PROTEASOME BETA-TYPE SUBUNIT; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME BETA-TYPE
SUBUNIT - Encephalitozoon cuniculi
Length = 235
Score = 96.3 bits (229), Expect = 6e-19
Identities = 57/159 (35%), Positives = 83/159 (52%), Gaps = 10/159 (6%)
Frame = +1
Query: 217 TTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDI 396
T TTV+ ++ G ++ DT GSYG LA+ R+ KV D LLG G+ +D QYL
Sbjct: 15 TGTTVVSFRYRDGIIMGADTRGSYGRLAKLSGVQRIFKVGDQTLLGMSGEISDMQYLVKT 74
Query: 397 IQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI---QDG----- 552
+ I+ + D ++ P+ H + R+LY+ RSK+ PL S V G+ DG
Sbjct: 75 L--TILTQE---DNRRIDPKGYHKMIQRILYSARSKISPLNLSVCVGGLNAASDGDRRTH 129
Query: 553 --EPFLGAVDKLGTAYEDAVISNGLGAYMATPLLRDAVD 663
E LG V+ LG Y V+ G+G Y+ P LR+ V+
Sbjct: 130 TREKMLGCVNHLGNFYFSDVVCTGIGGYLVLPFLRNRVE 168
>UniRef50_A7AVH7 Cluster: Proteasome subunit beta type 4; n=1;
Babesia bovis|Rep: Proteasome subunit beta type 4 -
Babesia bovis
Length = 226
Score = 94.3 bits (224), Expect = 3e-18
Identities = 49/128 (38%), Positives = 70/128 (54%), Gaps = 4/128 (3%)
Frame = +1
Query: 283 SYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQ----QKIIDERCVGDGLQLK 450
SYG R + R+ K+ + GD AD QY+ ++Q ++++D L
Sbjct: 25 SYGRQNRTNNVQRIEKLAKDTIFCTSGDVADHQYITQLLQATVRREMLDNNNDHASCHLG 84
Query: 451 PRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKLGTAYEDAVISNGLGAY 630
P +LH +L RV Y +RSKM+PLWNS +VAG+ PFLG D GT Y+D + G+G Y
Sbjct: 85 PEALHNYLGRVFYARRSKMNPLWNSAIVAGVSQNGPFLGYADMYGTQYKDDFVVTGMGKY 144
Query: 631 MATPLLRD 654
A LR+
Sbjct: 145 FAIGPLRE 152
>UniRef50_Q6BG89 Cluster: Proteasome subunit beta type; n=3;
Paramecium tetraurelia|Rep: Proteasome subunit beta type
- Paramecium tetraurelia
Length = 236
Score = 93.9 bits (223), Expect = 3e-18
Identities = 45/151 (29%), Positives = 82/151 (54%)
Frame = +1
Query: 196 HSASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYAD 375
H+ SP+ T +VI + ++ G ++ DTL SYGS+A F++ ++ +++ + G+++D
Sbjct: 13 HTTSPVVTGGSVIALVYNGGVIVGTDTLCSYGSMAAFKNVKKIAQISKNTIYASSGEFSD 72
Query: 376 FQYLKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGE 555
FQ + + + DG+ P+ +L R+ Y KR K++PL+ V+AG +GE
Sbjct: 73 FQQVVKELAKIDRSALQYDDGVHPSPKDYGNFLARLSYKKRCKINPLYLQNVIAGFHNGE 132
Query: 556 PFLGAVDKLGTAYEDAVISNGLGAYMATPLL 648
+L VD GT E I+ G +Y ++
Sbjct: 133 RYLSLVDIYGTYLESNFITTGFASYFCKAII 163
>UniRef50_Q7R5Z3 Cluster: GLP_81_66910_67563; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_81_66910_67563 - Giardia lamblia
ATCC 50803
Length = 217
Score = 92.3 bits (219), Expect = 1e-17
Identities = 52/162 (32%), Positives = 88/162 (54%), Gaps = 1/162 (0%)
Frame = +1
Query: 217 TTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDI 396
T TV+ V G ++A DT+ +YGS R + R++ V L+G GD ADF+
Sbjct: 6 TGGTVVAVAHKDGVLMAADTVLNYGSTRRTDNYERIIPVGTHTLIGFTGDEADFKDSLYT 65
Query: 397 IQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGE-PFLGAV 573
++ + RC G R +H +L Y+ R +MDP++N Y++ G + GE P++G V
Sbjct: 66 LKSMHREARCHGTP-PPSTREIHGFLATRNYSSRLEMDPIYNGYIIGGCEPGESPYIGVV 124
Query: 574 DKLGTAYEDAVISNGLGAYMATPLLRDAVDKGPLDQETAIAV 699
D GT + + + G+G + A P+LR+ G + ++ A+A+
Sbjct: 125 DLRGTQFTASFFATGMGRHYALPVLREGWKPG-ISKDEAVAL 165
>UniRef50_Q9U570 Cluster: Proteasome subunit beta type; n=6;
Plasmodium|Rep: Proteasome subunit beta type -
Plasmodium falciparum
Length = 265
Score = 89.4 bits (212), Expect = 7e-17
Identities = 40/114 (35%), Positives = 73/114 (64%), Gaps = 2/114 (1%)
Frame = +1
Query: 208 PITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYL 387
P+ T T+VI +K+ G +IA D SYGS A+F++ R+ K+N+ ++G G+ AD QYL
Sbjct: 5 PVVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYL 64
Query: 388 KDIIQQKIIDERCVGDGLQ--LKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI 543
+++ +K I+ + P+ H +++RV Y +++++DPL+N+ ++AGI
Sbjct: 65 HELLTRKNINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGI 118
>UniRef50_Q5CRD6 Cluster: Proteasome subunit beta7; NTN hydrolase
fold; n=2; Cryptosporidium|Rep: Proteasome subunit
beta7; NTN hydrolase fold - Cryptosporidium parvum Iowa
II
Length = 310
Score = 68.5 bits (160), Expect = 1e-10
Identities = 35/99 (35%), Positives = 63/99 (63%), Gaps = 1/99 (1%)
Frame = +1
Query: 361 GDYADFQYLKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAG 540
G+++DFQ + + +++K ++ G+ K S +++ V Y +R+KMDPL N +VAG
Sbjct: 141 GEFSDFQNIIERVEEKAAEDFFEGNFKSAKEYS--GYISAVHYQRRNKMDPLLNDIIVAG 198
Query: 541 IQ-DGEPFLGAVDKLGTAYEDAVISNGLGAYMATPLLRD 654
++ DG + +VD LGT +++ I++G+ Y+A LLRD
Sbjct: 199 LRKDGSKEIYSVDPLGTRFDEDFIASGMAEYLAITLLRD 237
>UniRef50_Q8TW10 Cluster: Protease subunit of the proteasome; n=2;
Euryarchaeota|Rep: Protease subunit of the proteasome -
Methanopyrus kandleri
Length = 210
Score = 62.1 bits (144), Expect = 1e-08
Identities = 42/166 (25%), Positives = 78/166 (46%), Gaps = 3/166 (1%)
Frame = +1
Query: 211 ITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLK 390
+T TT +G+ DKG V+A D G+L + ++ +++D I + G AD Q +
Sbjct: 7 LTKGTTTVGILADKGVVLAADRRAVMGNLIAGKQVKKIFRIHDYIGVTTAGSVADAQKIV 66
Query: 391 DII--QQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFL 564
D++ + ++ + R + R+L ++ VL++ P +V G D +P L
Sbjct: 67 DLMRAEARLYELR---HNRMISARALANMISHVLHSSLKAFRPYLVQLIVGGFNDDDPAL 123
Query: 565 GAVDKLGTAYEDAVISNGLGAYMATPLLRDAVDKG-PLDQETAIAV 699
+D G+ E+ + G G+ A +L ++G LD +AV
Sbjct: 124 YNLDPSGSIIEEDYTATGSGSPTAYGVLEAEYEEGMSLDDAIEVAV 169
>UniRef50_Q8SRH6 Cluster: 20S PROTEASOME ALPHA-TYPE SUBUNIT; n=1;
Encephalitozoon cuniculi|Rep: 20S PROTEASOME ALPHA-TYPE
SUBUNIT - Encephalitozoon cuniculi
Length = 290
Score = 58.8 bits (136), Expect = 1e-07
Identities = 44/149 (29%), Positives = 76/149 (51%), Gaps = 2/149 (1%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQ--YLKDII 399
T I +K V+AGDT S + R+ ++ +V D +L G G YAD Y+K +
Sbjct: 92 TTICLKQGDFIVVAGDTRHSSSMVINSREMSKIFQVGDFLLTGTGF-YADTHEVYVKMVY 150
Query: 400 QQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDK 579
+ I + V D + + S L+++LY+KR P ++ V++G + G+P++ + D
Sbjct: 151 E---IRQYEVDDSINI--HSAANLLSKILYSKR--FFPYYSFCVLSGFEKGKPYVYSYDP 203
Query: 580 LGTAYEDAVISNGLGAYMATPLLRDAVDK 666
+G+ + +G G M PLL +DK
Sbjct: 204 IGSFGSVTCVCSGSGRSMIQPLLDSFIDK 232
>UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum
pernix|Rep: Proteasome beta subunit - Aeropyrum pernix
Length = 203
Score = 58.0 bits (134), Expect = 2e-07
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 1/149 (0%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
T +G++ + G V+A D SYG R+ ++ +ND I + G Y D L I++
Sbjct: 7 TALGIRVEDGVVLAADKRMSYGGFILSRNFKKIFVINDRIGIAFAGLYGDMGGLVRIVEG 66
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQ-DGEPFLGAVDKL 582
+ + + G R++ +L+ +LY+ K P +V GI GEP L +D L
Sbjct: 67 Q-MRLASLETGKPATVRNVAKFLSSLLYS--YKFFPFNVEAIVGGIDPGGEPKLYVLDPL 123
Query: 583 GTAYEDAVISNGLGAYMATPLLRDAVDKG 669
G+ E+ ++ G GA A LL +G
Sbjct: 124 GSIIEEDYVAAGTGATTAFGLLEHVYKRG 152
>UniRef50_Q980L4 Cluster: Proteasome subunit; n=4;
Sulfolobaceae|Rep: Proteasome subunit - Sulfolobus
solfataricus
Length = 196
Score = 55.6 bits (128), Expect = 1e-06
Identities = 40/146 (27%), Positives = 68/146 (46%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
T +G+K + G V+A + SYG + +V K+N ++ G G Y D Q L I+
Sbjct: 7 TAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFLMAG-AGIYGDLQTLTRIMNV 65
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKLG 585
+I V G + + L+ +LY + K+ P + + G+ + P L +D +G
Sbjct: 66 EIKYYE-VSTGKPISVHAAAKLLSVILY--QYKVMPFISEILFGGVDEKGPQLYVLDPIG 122
Query: 586 TAYEDAVISNGLGAYMATPLLRDAVD 663
+ ED + G GA +A +L D
Sbjct: 123 SLIEDNYAAVGSGARIAIGVLESEYD 148
>UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2;
Desulfurococcales|Rep: Proteasome beta subunit -
Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
Length = 204
Score = 55.6 bits (128), Expect = 1e-06
Identities = 41/151 (27%), Positives = 73/151 (48%), Gaps = 1/151 (0%)
Frame = +1
Query: 217 TTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDI 396
T T +G++ V+A + SYG + +V K+ D + L G +AD Q + I
Sbjct: 7 TGATAVGIRGAGYVVLAAEKRVSYGGFIISKTARKVYKITDYLGLALAGLFADLQAISKI 66
Query: 397 IQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQ-DGEPFLGAV 573
++ + I+ + G ++ R++ L +LY+ K P + +V G++ DG L +
Sbjct: 67 LRAE-IEYYNIVTGRRISVRAVARLLATILYS--YKYYPFLSETLVGGLEADGTAKLYVM 123
Query: 574 DKLGTAYEDAVISNGLGAYMATPLLRDAVDK 666
D LG+ ED + G GA +A +L + K
Sbjct: 124 DPLGSLIEDDYAAIGSGAPIAIGILENGYSK 154
>UniRef50_P20618 Cluster: Proteasome subunit beta type-1 precursor;
n=27; Eumetazoa|Rep: Proteasome subunit beta type-1
precursor - Homo sapiens (Human)
Length = 241
Score = 54.0 bits (124), Expect = 3e-06
Identities = 41/183 (22%), Positives = 83/183 (45%), Gaps = 1/183 (0%)
Frame = +1
Query: 115 SPGAFYNFPGNASTIAPSRHGVQDFTAHSASPITTTTTVIGVKFDKGCVIAGDTLGSYGS 294
S A Y+ PG + P R + + T++ + + ++A DT S G
Sbjct: 3 SSTAMYSAPGRDLGMEPHR-AAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGF 61
Query: 295 LARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERCVGDGLQLKPRSLHCWL 474
RD P+ K+ D ++GC G + D L II+ ++ + + + ++ L
Sbjct: 62 SIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYK-HSNNKAMTTGAIAAML 120
Query: 475 TRVLYNKRSKMDPLWNSYVVAGI-QDGEPFLGAVDKLGTAYEDAVISNGLGAYMATPLLR 651
+ +LY++R P + ++ G+ ++G+ + + D +G+ D+ + G + M PLL
Sbjct: 121 STILYSRR--FFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLD 178
Query: 652 DAV 660
+ V
Sbjct: 179 NQV 181
>UniRef50_Q9IB84 Cluster: Proteasome subunit beta type-1-A; n=14;
Deuterostomia|Rep: Proteasome subunit beta type-1-A -
Carassius auratus (Goldfish)
Length = 238
Score = 53.2 bits (122), Expect = 6e-06
Identities = 44/176 (25%), Positives = 80/176 (45%), Gaps = 10/176 (5%)
Frame = +1
Query: 196 HSASPITTTT-TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYA 372
H SP TV+ V + ++A DT S G RD P+ K+ D ++GC G +
Sbjct: 25 HKFSPYAFNGGTVLAVAGEDFALVASDTRLSEGYSIHSRDSPKCYKLTDTTVIGCSGFHG 84
Query: 373 DFQYLKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI-QD 549
D L II+ ++ + + + ++ L+ +LY +R P + ++ G+ ++
Sbjct: 85 DCLTLTKIIEARLKMYK-HSNNKSMTSGAIAAMLSTILYGRR--FFPYYVYNIIGGLDEE 141
Query: 550 GEPFLGAVDKLGTAYEDAVISNGLGAYMATPLL--------RDAVDKGPLDQETAI 693
G + + D +G+ D + G + M PLL + V++ PL QE A+
Sbjct: 142 GRGAVYSFDPVGSYQRDTYKAGGSASAMLQPLLDNQIGFKNMENVEQVPLSQEKAV 197
>UniRef50_A5UM14 Cluster: Proteasome, beta subunit; n=1;
Methanobrevibacter smithii ATCC 35061|Rep: Proteasome,
beta subunit - Methanobrevibacter smithii (strain PS /
ATCC 35061 / DSM 861)
Length = 204
Score = 52.8 bits (121), Expect = 8e-06
Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 1/145 (0%)
Frame = +1
Query: 223 TTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQ 402
TT +G+ G V A + S G+L + ++ K+ND I+ G D Q L II+
Sbjct: 9 TTTVGITCKDGVVFASERRASMGNLVAHKVAEKIFKINDHIVTTIAGSVGDAQNLMKIIE 68
Query: 403 QKI-IDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDK 579
++ + + D + +K + +L + P++ ++ G+ +P L ++D
Sbjct: 69 AEVSLYQMRNNDKISVKAAA--SVTANIL-----RSGPMYVQTLLGGMDGDKPSLYSLDP 121
Query: 580 LGTAYEDAVISNGLGAYMATPLLRD 654
G ED IS G G+ +A +L D
Sbjct: 122 AGGMIEDTYISTGSGSIVAYGVLED 146
>UniRef50_A0RU86 Cluster: 20S proteasome, alpha and beta subunit;
n=1; Cenarchaeum symbiosum|Rep: 20S proteasome, alpha
and beta subunit - Cenarchaeum symbiosum
Length = 193
Score = 52.4 bits (120), Expect = 1e-05
Identities = 38/156 (24%), Positives = 72/156 (46%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
T +G+ + G ++A + +YG+ ++ + ++ + C G AD Q L I
Sbjct: 5 TAVGITYAGGVILASEKRIAYGNFLVSKNTRKTFQITPYVGAACAGLVADMQILSLQI-S 63
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKLG 585
+ R + + P S+ ++ ++Y +R PL +V G+ GEP + +D LG
Sbjct: 64 ALAKIRKMDLKRDIPPNSVAKMMSNMMYERR--FFPLLTQVIVGGVV-GEPAIYTLDSLG 120
Query: 586 TAYEDAVISNGLGAYMATPLLRDAVDKGPLDQETAI 693
+ D + G GA MA +L D K + ++ A+
Sbjct: 121 SVLPDEYAAVGTGAEMALGVL-DPQFKSGMSEKDAV 155
>UniRef50_Q8ZST5 Cluster: Proteasome, beta subunit; n=5;
Thermoproteaceae|Rep: Proteasome, beta subunit -
Pyrobaculum aerophilum
Length = 203
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 2/143 (1%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
T +G+K G V+A + SYG +V ++D + + G AD Q L I++
Sbjct: 10 TAVGIKAKDGVVLAAEKRVSYGFYTLSSAGKKVFVIDDKLAIASAGIIADMQTLAKILK- 68
Query: 406 KIIDERCVGDGLQLKP--RSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDK 579
++ + ++ KP S+ L+ +++++R P + +V GI + P L +D
Sbjct: 69 --LNAKAYELEMKRKPSTHSMARLLSVIMFSRR--FMPFFAEVLVGGIDEEGPHLIVMDP 124
Query: 580 LGTAYEDAVISNGLGAYMATPLL 648
LG+ ED + G GA +A +L
Sbjct: 125 LGSLIEDNYAALGTGAKLAVAVL 147
>UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 204
Score = 50.8 bits (116), Expect = 3e-05
Identities = 38/160 (23%), Positives = 77/160 (48%), Gaps = 2/160 (1%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
T +G++ G V+A + SYG + +V ++ D + + G AD Q L I++
Sbjct: 7 TTVGIRVSDGVVLAAEKRVSYGLYLMSKSGKKVYRILDKMGMASAGLMADMQTLARIVEA 66
Query: 406 KI-IDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKL 582
++ + E + + K ++ L+ +LY +R + P + VV G+ + L ++D +
Sbjct: 67 EMRLYE--LDSNISPKVWTVAKLLSYILYERR--LFPYYAEIVVGGLDEEGSHLYSLDPI 122
Query: 583 GTAYEDAVISNGLGAYMATPLLRDAVDKG-PLDQETAIAV 699
G ED ++ G G +A ++ K LD+ ++A+
Sbjct: 123 GAIIEDDYVALGSGTQLAISIVESNYKKDMSLDEALSLAL 162
>UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1;
Staphylothermus marinus F1|Rep: 20S proteasome, A and B
subunits - Staphylothermus marinus (strain ATCC 43588 /
DSM 3639 / F1)
Length = 213
Score = 50.4 bits (115), Expect = 4e-05
Identities = 35/141 (24%), Positives = 69/141 (48%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
TV+G+K G VIAG+ +Y ++ +V + + +G G D Q++ ++
Sbjct: 19 TVLGIKAVNGVVIAGEKRLTYDGYVLSKNTRKVHPITKHVGIGFAGLVGDAQFIIRALRM 78
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVDKLG 585
+ + + G +++ R L L+ +LY+ K+ PL VV G + P + +D +G
Sbjct: 79 E-AENYELQLGREIRVRGLAKILSLILYS--YKLAPLMTEVVVGGFDEKGPQIYVLDPVG 135
Query: 586 TAYEDAVISNGLGAYMATPLL 648
+ ED ++ G G +A ++
Sbjct: 136 SLIEDKYVALGSGGPIALGII 156
>UniRef50_UPI000150A719 Cluster: Proteasome A-type and B-type family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Proteasome A-type and B-type family protein -
Tetrahymena thermophila SB210
Length = 247
Score = 50.0 bits (114), Expect = 5e-05
Identities = 41/163 (25%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Frame = +1
Query: 163 PSRHGVQDFTAHSASP-ITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVND 339
P +++ + +P + TV + ++AGD S G RD ++ ++ D
Sbjct: 23 PQADNIKEAKRNEFNPYVFNAGTVCAIAHGDFVIVAGDKRISQGYSIVSRDISKLARLTD 82
Query: 340 LILLGCGGDYADFQYLKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLW 519
+ L G YADF L + ++ + +G Q R++ L+R LY KR P +
Sbjct: 83 NVFLATSGMYADFAALSKQLSARLHMYK-YNNGKQANMRAIASLLSRTLYYKR--FFPYY 139
Query: 520 NSYVVAGIQD-GEPFLGAVDKLGTAYEDAVISNGLGAYMATPL 645
++AG D GE + D +G+ G GA + TP+
Sbjct: 140 TFNLLAGFDDKGEGLVINYDAVGSGDFKKYAVLGSGAQLITPV 182
>UniRef50_Q74MP5 Cluster: NEQ203; n=1; Nanoarchaeum equitans|Rep:
NEQ203 - Nanoarchaeum equitans
Length = 196
Score = 48.0 bits (109), Expect = 2e-04
Identities = 33/126 (26%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Frame = +1
Query: 223 TTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQ 402
TT+IG+K G V+A D S G++ + +++ + D ILL G AD Q++ I++
Sbjct: 2 TTIIGIKARDGVVLASDKQASMGNIVEDKRAQKIIPITDYILLAGSGTVADLQHIAKILK 61
Query: 403 QKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPF-LGAVDK 579
+ + R + + L+ +LY R ++PL ++AG + + F + ++D
Sbjct: 62 TE-LKLRELYSRRTMNVIEAANLLSHLLYQNRFYLNPL--GLLIAGPINSKEFGIYSLDG 118
Query: 580 LGTAYE 597
+G E
Sbjct: 119 IGAISE 124
>UniRef50_P25043 Cluster: Proteasome component PUP1 precursor; n=19;
Eukaryota|Rep: Proteasome component PUP1 precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 261
Score = 46.4 bits (105), Expect = 7e-04
Identities = 23/74 (31%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
Frame = +1
Query: 193 AHSASPITTT-TTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDY 369
+H+ T+T TT++GVKF+ G VIA DT + G + ++C ++ +++ I G
Sbjct: 19 SHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTA 78
Query: 370 ADFQYLKDIIQQKI 411
AD + + +I I
Sbjct: 79 ADTEAVTQLIGSNI 92
>UniRef50_Q6CA23 Cluster: Yarrowia lipolytica chromosome D of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome D of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 238
Score = 46.0 bits (104), Expect = 9e-04
Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 1/141 (0%)
Frame = +1
Query: 247 DKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERC 426
D ++AGDT + G R P+V V D IL+ G AD L + I+Q ++
Sbjct: 43 DDFALLAGDTRNTTGYSINSRYQPKVFDVGDNILVTANGFSADGDALIENIKQH-VELYH 101
Query: 427 VGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI-QDGEPFLGAVDKLGTAYEDA 603
+ LK +S + +LYNKR P + ++AG+ ++G+ + + D +G+ +
Sbjct: 102 YQNNKPLKVQSCARAIQHMLYNKR--FFPYYVHTIIAGLDEEGKGAVYSYDPVGSYEREF 159
Query: 604 VISNGLGAYMATPLLRDAVDK 666
+ G A + P L V+K
Sbjct: 160 CRAGGSAASLVMPFLDSQVNK 180
>UniRef50_A0BPF5 Cluster: Chromosome undetermined scaffold_12, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_12,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 239
Score = 45.2 bits (102), Expect = 0.002
Identities = 30/108 (27%), Positives = 54/108 (50%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
TV+ V ++AGDT S G RD ++ ++ D +L G YADF L+ +QQ
Sbjct: 38 TVLAVGIPGAVIVAGDTRLSNGYNILSRDATKLSQLTDKCVLATAGQYADFIALRKFLQQ 97
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQD 549
++ + +Q ++ L+R LY++R P + ++AG+ +
Sbjct: 98 RLQLYEFQNE-VQASTETVAHLLSRELYSRR--FFPYYTFNLLAGLDE 142
>UniRef50_Q98S25 Cluster: Proteasome subunit beta type; n=1;
Guillardia theta|Rep: Proteasome subunit beta type -
Guillardia theta (Cryptomonas phi)
Length = 200
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = +1
Query: 247 DKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERC 426
D C+ + GS L F+ ++ K+++ I++G G D K+I++ +I
Sbjct: 15 DSLCIASDSENGSVSYLTEFKT-QKIFKLHEDIIIGIVGLLGDIYGFKEILEYEI-SIVT 72
Query: 427 VGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI-QDGEPFLGAVDKLG 585
+ +++P + ++ +LY KR +P +VAG ++G+PFLG VD +G
Sbjct: 73 KKEQKKMEPIEILSLISTLLYKKR--FNPYLLEILVAGFTENGKPFLGTVDCIG 124
>UniRef50_A5K9H5 Cluster: Proteasome subunit beta type; n=1;
Plasmodium vivax|Rep: Proteasome subunit beta type -
Plasmodium vivax
Length = 241
Score = 44.4 bits (100), Expect = 0.003
Identities = 39/151 (25%), Positives = 72/151 (47%), Gaps = 4/151 (2%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
TVIGV ++A DT S R CP++ K+ D ++G G +D + L ++++
Sbjct: 40 TVIGVTGKDYVILAADTRLSLSYSIYTRHCPKISKLTDKCIIGSSGMQSDIKTLHSLLKK 99
Query: 406 KI---IDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI-QDGEPFLGAV 573
KI + E + + R L C +LY++R P + ++AG+ D + L
Sbjct: 100 KIELFVLEHAHYPDIHVIARLL-C---VILYSRR--FFPYYTFNLLAGVSNDSKGVLYNY 153
Query: 574 DKLGTAYEDAVISNGLGAYMATPLLRDAVDK 666
D +G+ E G G+ + P+L + +++
Sbjct: 154 DAIGSYCEATHSCVGSGSALILPILDNRMEQ 184
>UniRef50_A4FNF9 Cluster: Diguanylate cyclase/phosphodiesterase with
PAS/PAC and GAF sensor; n=2; Saccharopolyspora erythraea
NRRL 2338|Rep: Diguanylate cyclase/phosphodiesterase with
PAS/PAC and GAF sensor - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 929
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/78 (30%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Frame = +1
Query: 220 TTTVIGVKFDKGCVIAGDTLGS-YGSLARFRDCP-RVMKVNDLILLGCGGDYADFQYLKD 393
T +G +G A D G+ Y SLAR +D P +++KV+ + G GGD +DF +
Sbjct: 807 TRHAMGELVQRGVRFAVDDFGTGYSSLARLKDLPAQIIKVDRRFVSGVGGDASDFAVARA 866
Query: 394 IIQQ-KIIDERCVGDGLQ 444
++ + + +CV +G++
Sbjct: 867 VVDMARAMGRQCVAEGVE 884
>UniRef50_A0CN28 Cluster: Proteasome subunit beta type; n=4;
Paramecium tetraurelia|Rep: Proteasome subunit beta type
- Paramecium tetraurelia
Length = 275
Score = 44.0 bits (99), Expect = 0.004
Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 1/160 (0%)
Frame = +1
Query: 208 PITTT-TTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQY 384
P T T TT++GV FD G V+A DT + GS+ ++C ++ + I G AD +
Sbjct: 34 PFTKTGTTIVGVIFDGGVVMAADTRATAGSIVADKNCEKLHPLAPNIWAAGAGTAADLHH 93
Query: 385 LKDIIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFL 564
K+ +R + Q + + LT L+ R + + ++ GI P L
Sbjct: 94 QCAHFNAKLKLQR-LNLNRQSRVNEVITKLTAKLFPYRGHIGV---ALIIGGIDSNGPQL 149
Query: 565 GAVDKLGTAYEDAVISNGLGAYMATPLLRDAVDKGPLDQE 684
+V G S G G+ A +L G Q+
Sbjct: 150 ASVSPHGNYVYHPFQSMGSGSLAALGILEAKFQDGLTKQQ 189
>UniRef50_Q7QWS6 Cluster: Proteasome subunit beta type; n=1; Giardia
lamblia ATCC 50803|Rep: Proteasome subunit beta type -
Giardia lamblia ATCC 50803
Length = 254
Score = 43.6 bits (98), Expect = 0.005
Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 2/147 (1%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
T+I + +IAGDT S G R+ +V V D I+ G +AD Q L +
Sbjct: 57 TIIAIAGPDFAMIAGDTRLSEGYNILSRNVRKVFPVTDKIVYAASGMHADVQRL--LKHM 114
Query: 406 KI-IDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI-QDGEPFLGAVDK 579
KI E + ++ L+ ++Y +RS P + S +VAGI +G + + D
Sbjct: 115 KIESTEYYLKTQKEIAIEQFIRLLSAMMYYRRS--FPWYTSSIVAGIDSEGRGAVYSYDV 172
Query: 580 LGTAYEDAVISNGLGAYMATPLLRDAV 660
+G+ S G G M P+L +A+
Sbjct: 173 IGSTLRTRYGSAGTGNAMICPILDEAI 199
>UniRef50_Q5CUK0 Cluster: Proteasome subunit beta type; n=2;
Cryptosporidium|Rep: Proteasome subunit beta type -
Cryptosporidium parvum Iowa II
Length = 279
Score = 43.6 bits (98), Expect = 0.005
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +1
Query: 211 ITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLK 390
+ T TT++GV + V+ DT + G + +DC ++ +++D I G AD ++
Sbjct: 38 VKTGTTIVGVACNDCVVLGADTRATNGPIVADKDCEKIHRLSDNIFAAGAGTAADLDHVT 97
Query: 391 DIIQQKIIDERCVGDGLQLKPRSLHC--WLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFL 564
+I+ + ++ + KPR H L+ LY + + +VAG F+
Sbjct: 98 SLIEGNLELQKL---QMNRKPRVAHAVSMLSDHLYKYQGYIGA---HLIVAGSDSTGNFV 151
Query: 565 GAVDKLGTAYEDAVISNGLGAYMATPLLRDAVDKGPLDQE 684
V G + S G G+ A +L G + E
Sbjct: 152 FQVSANGCIMQLPFTSMGSGSLCARSILEARYRDGLTESE 191
>UniRef50_Q1ZXN1 Cluster: Proteasome subunit beta type; n=2;
Dictyostelium discoideum|Rep: Proteasome subunit beta
type - Dictyostelium discoideum AX4
Length = 236
Score = 43.2 bits (97), Expect = 0.006
Identities = 40/149 (26%), Positives = 68/149 (45%), Gaps = 2/149 (1%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLA-RFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQ 402
TV+ V CVIAGDT S G + R ++ ++ +L G AD L+ +
Sbjct: 32 TVLAVAGKDYCVIAGDTRMSDGGYGIQTRKYTKIFQLTKKCVLATSGMQADTIALQKRL- 90
Query: 403 QKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI-QDGEPFLGAVDK 579
+ +++ G + ++ +L+ LY KR P + +VAG+ + GE ++ D
Sbjct: 91 KSMLESFEKEHGKPMSTPAIAQFLSNTLYYKR--FFPYYTFNLVAGVDEQGEGWIWTYDA 148
Query: 580 LGTAYEDAVISNGLGAYMATPLLRDAVDK 666
+G+ S G G + PLL + V K
Sbjct: 149 VGSHERVKYSSQGSGNQLVIPLLDNQVAK 177
>UniRef50_Q4YMY0 Cluster: Proteasome subunit beta type; n=5;
Plasmodium|Rep: Proteasome subunit beta type -
Plasmodium berghei
Length = 267
Score = 41.5 bits (93), Expect = 0.019
Identities = 19/59 (32%), Positives = 33/59 (55%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQ 402
TVIG+ + ++AGDT S R+CP++ K+ D ++G G +D + L ++Q
Sbjct: 41 TVIGLTGNNYVILAGDTRLSLSYSIYTRNCPKISKITDKCIIGSSGMQSDIKTLHSLLQ 99
>UniRef50_Q6E6B2 Cluster: Proteasome beta-type subunit-like protein;
n=1; Antonospora locustae|Rep: Proteasome beta-type
subunit-like protein - Antonospora locustae (Nosema
locustae)
Length = 190
Score = 40.7 bits (91), Expect = 0.034
Identities = 21/67 (31%), Positives = 37/67 (55%)
Frame = +1
Query: 187 FTAHSASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGD 366
F+AH A P T TT++G++F G + DT + G + ++C ++ ++ D I G
Sbjct: 10 FSAHLA-PKKTGTTIVGLRFAGGVALFADTRATIGDVVEDKNCFKLHQLADTIHCAGAGT 68
Query: 367 YADFQYL 387
AD ++L
Sbjct: 69 AADTEHL 75
>UniRef50_Q8SQN7 Cluster: Proteasome subunit beta type; n=1;
Encephalitozoon cuniculi|Rep: Proteasome subunit beta
type - Encephalitozoon cuniculi
Length = 227
Score = 40.3 bits (90), Expect = 0.044
Identities = 16/53 (30%), Positives = 31/53 (58%)
Frame = +1
Query: 217 TTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYAD 375
T TT++G+K+ G ++A DT + G + ++C ++ ++ D I+ G AD
Sbjct: 5 TGTTIVGMKYKTGVILAADTRSTQGPVVSDKNCVKIHQITDKIMCCGAGTAAD 57
>UniRef50_Q5AF53 Cluster: Putative uncharacterized protein PRE7;
n=1; Candida albicans|Rep: Putative uncharacterized
protein PRE7 - Candida albicans (Yeast)
Length = 127
Score = 39.9 bits (89), Expect = 0.059
Identities = 28/91 (30%), Positives = 46/91 (50%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
TV+G+ + V+AGDT G + R ++ V D IL+ G AD L D +Q
Sbjct: 34 TVLGIAGEDFAVLAGDTRQVEGYSIQSRYESKIHDVGDDILMTANGFAADGVALIDRFKQ 93
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKR 498
+I + +G +L +S ++ ++LY KR
Sbjct: 94 SLIWYKFDNNGKKLAIKSAARYIQQLLYGKR 124
>UniRef50_Q9N9W8 Cluster: Proteasome subunit beta type-3; n=2;
Giardia intestinalis|Rep: Proteasome subunit beta type-3
- Giardia lamblia (Giardia intestinalis)
Length = 207
Score = 39.9 bits (89), Expect = 0.059
Identities = 35/124 (28%), Positives = 63/124 (50%), Gaps = 3/124 (2%)
Frame = +1
Query: 223 TTVIGVKFDKGCVIAGDT-LG-SYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDI 396
+ +IG+K +A D LG SY +L + R+ +++ LLG G D
Sbjct: 10 SALIGIKGXDCVALAADKRLGCSYQTLTIGNE-ERIFRLSQSCLLGLAGLQTDVLTTYRQ 68
Query: 397 IQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQ-DGEPFLGAV 573
I+ K + + + +++PR+ ++ LY R P + S ++AG + DG+P+LGA+
Sbjct: 69 IRMKS-NLYHLQEDREIRPRATAKMISSFLYKHR--FGPYFISPIIAGFEADGKPYLGAM 125
Query: 574 DKLG 585
D +G
Sbjct: 126 DTIG 129
>UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8;
Halobacteriaceae|Rep: Proteasome subunit alpha 1 -
Haloarcula marismortui (Halobacterium marismortui)
Length = 260
Score = 39.5 bits (88), Expect = 0.078
Identities = 39/163 (23%), Positives = 73/163 (44%), Gaps = 4/163 (2%)
Frame = +1
Query: 223 TTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQ 402
T IGV+ G V+A D + R ++ K +D I + G AD + L D +
Sbjct: 37 TASIGVRTSDGVVLAVDKRIRSPLMER-SSVEKIHKADDHIGIASAGHVADARQLIDFAR 95
Query: 403 QKI-IDERCVGD--GLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAV 573
++ +++ G+ G++ + + ++ + Y + P + ++ GI +GEP L
Sbjct: 96 RQAQVNQLRYGEPVGVETLTKEITDYIQQ--YTQVGGARPFGVALIIGGIVNGEPRLFET 153
Query: 574 DKLGTAYEDAVISNGLGAYMATPLLRDAVDKG-PLDQETAIAV 699
D GT YE ++ G L + D+G LD+ +A+
Sbjct: 154 DPSGTPYEWKALAVGADRGDIRDYLEEHYDEGMDLDEGVDLAL 196
>UniRef50_Q8SR11 Cluster: Proteasome subunit beta type; n=1;
Encephalitozoon cuniculi|Rep: Proteasome subunit beta
type - Encephalitozoon cuniculi
Length = 203
Score = 39.1 bits (87), Expect = 0.10
Identities = 27/111 (24%), Positives = 51/111 (45%)
Frame = +1
Query: 217 TTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDI 396
T TT+I +K+D G +I D+ S G+ R ++ ++ D I + G AD Q +
Sbjct: 9 TGTTIIAIKYDDGVLIGADSRTSMGAYVSSRVTDKLTQITDKIFVCRSGSSADTQMISSY 68
Query: 397 IQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQD 549
++ + + D + R+ ++++Y S + L +VAG D
Sbjct: 69 LRMYLSMYSQLEDSIPQVQRAA-ALASKIIYENPSLLAGL----IVAGYDD 114
>UniRef50_UPI00004991C1 Cluster: proteasome beta subunit; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome beta
subunit - Entamoeba histolytica HM-1:IMSS
Length = 213
Score = 38.3 bits (85), Expect = 0.18
Identities = 21/76 (27%), Positives = 40/76 (52%)
Frame = +1
Query: 184 DFTAHSASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGG 363
+FT ++ PI+ TT+IGV ++ G ++ D S GS+ R ++ V+D I + G
Sbjct: 2 EFTHNAYQPISLGTTIIGVVYNGGVLLGADGRTSMGSIVVNRCKNKIRMVSDSIGMCTAG 61
Query: 364 DYADFQYLKDIIQQKI 411
A + + D ++ +
Sbjct: 62 TAAHSETIGDYVKHAL 77
>UniRef50_Q98RS2 Cluster: Proteasome subunit beta type; n=1;
Guillardia theta|Rep: Proteasome subunit beta type -
Guillardia theta (Cryptomonas phi)
Length = 239
Score = 38.3 bits (85), Expect = 0.18
Identities = 27/107 (25%), Positives = 53/107 (49%)
Frame = +1
Query: 229 VIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQK 408
V+ + +K CV+A DT S G R R++K+++L LLG G +D L ++ +
Sbjct: 40 VLAITGNKFCVMASDTRISMGYSIPSRLNLRILKISNLCLLGSSGMISDINILHQKLRNE 99
Query: 409 IIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQD 549
I + + + +L + + +LY++R P + ++ GI +
Sbjct: 100 IFRLKYL-NNTELNLNGIVYLTSSLLYSRR--FFPFYTFNILTGINE 143
>UniRef50_P49721 Cluster: Proteasome subunit beta type-2; n=40;
Fungi/Metazoa group|Rep: Proteasome subunit beta type-2
- Homo sapiens (Human)
Length = 201
Score = 38.3 bits (85), Expect = 0.18
Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 1/141 (0%)
Frame = +1
Query: 229 VIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQK 408
+IG++ ++A D + + + D ++ K+++ ILL C G+ D + I QK
Sbjct: 4 LIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYI-QK 62
Query: 409 IIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGE-PFLGAVDKLG 585
+ + +G +L P + + R L + P + ++AG + E P L +D L
Sbjct: 63 NVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLA 122
Query: 586 TAYEDAVISNGLGAYMATPLL 648
+ ++G GA++ +L
Sbjct: 123 ALAKAPFAAHGYGAFLTLSIL 143
>UniRef50_P28072 Cluster: Proteasome subunit beta type-6 precursor;
n=43; Bilateria|Rep: Proteasome subunit beta type-6
precursor - Homo sapiens (Human)
Length = 239
Score = 37.9 bits (84), Expect = 0.24
Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Frame = +1
Query: 175 GVQDFTAHSAS-PITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILL 351
G + FT S ++T TT++ V+FD G V+ D+ + GS R ++ ++D I
Sbjct: 18 GPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFC 77
Query: 352 GCGGDYADFQYLKDIIQQKI 411
G AD Q + D + ++
Sbjct: 78 CRSGSAADTQAVADAVTYQL 97
>UniRef50_Q4N2N3 Cluster: Proteasome beat subunit, putative; n=3;
Piroplasmida|Rep: Proteasome beat subunit, putative -
Theileria parva
Length = 218
Score = 37.1 bits (82), Expect = 0.41
Identities = 34/142 (23%), Positives = 63/142 (44%), Gaps = 1/142 (0%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
TVI ++ VIA DT S L R ++ K+ D +LG G AD L+ ++++
Sbjct: 17 TVIAATWNNYAVIAADTRLSQRYLIHTRFSTKLFKLTDKCILGTSGMQADMLALQSVLER 76
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI-QDGEPFLGAVDKL 582
+I R + ++ L+ VLY +R P + ++ GI + G+ + D +
Sbjct: 77 QIELYRYT-HNREPTFNAIAQLLSTVLYGRR--FFPYYTFNILCGIDEQGKGVVCGYDAV 133
Query: 583 GTAYEDAVISNGLGAYMATPLL 648
G + + G + + +L
Sbjct: 134 GNYNYEKYTAQGTSSSLVISVL 155
>UniRef50_A2F716 Cluster: Proteasome subunit beta type; n=1;
Trichomonas vaginalis G3|Rep: Proteasome subunit beta
type - Trichomonas vaginalis G3
Length = 224
Score = 37.1 bits (82), Expect = 0.41
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 1/145 (0%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
T IG+ D VI DT S R R+ K+N ++ G D ++
Sbjct: 22 TAIGICGDDYVVIGADTRLSVDYSIDSRHKARIFKMNSNCMISATGFDGDIDAFITRMRS 81
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQ-DGEPFLGAVDKL 582
+++ ++ S+ ++ LY+KR P + + +V GI +G+ L D +
Sbjct: 82 ILLNYENQHFH-EMSVESVARCVSNTLYSKR--FFPYYINILVGGINSEGKGKLYGYDPV 138
Query: 583 GTAYEDAVISNGLGAYMATPLLRDA 657
GT + SNG G+ +A PLL A
Sbjct: 139 GTIEDLHYDSNGSGSSLAAPLLDSA 163
>UniRef50_P49720 Cluster: Proteasome subunit beta type-3; n=85;
Eukaryota|Rep: Proteasome subunit beta type-3 - Homo
sapiens (Human)
Length = 205
Score = 37.1 bits (82), Expect = 0.41
Identities = 32/126 (25%), Positives = 61/126 (48%), Gaps = 5/126 (3%)
Frame = +1
Query: 250 KGCV-IAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQKIIDERC 426
K CV IA D + D ++ + D + +G G D Q + ++ ++ +
Sbjct: 17 KNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRL-NLYE 75
Query: 427 VGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI--QDGEPFLGAVDKLG--TAY 594
+ +G Q+KP +L + +LY KR P + V+AG+ + +PF+ ++D +G
Sbjct: 76 LKEGRQIKPYTLMSMVANLLYEKR--FGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVT 133
Query: 595 EDAVIS 612
+D V+S
Sbjct: 134 DDFVVS 139
>UniRef50_Q8T915 Cluster: AT05866p; n=1; Drosophila
melanogaster|Rep: AT05866p - Drosophila melanogaster
(Fruit fly)
Length = 322
Score = 36.7 bits (81), Expect = 0.55
Identities = 16/66 (24%), Positives = 35/66 (53%)
Frame = +1
Query: 214 TTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKD 393
TT TTV+G+ FD G +I ++ + G + + C +++++ I G D + L +
Sbjct: 47 TTGTTVVGIVFDGGVIIGAESRATSGGIVFSKTCRKIIELQANIFAAGAGTARDTKALVE 106
Query: 394 IIQQKI 411
+ + ++
Sbjct: 107 LTRAQL 112
>UniRef50_Q8LD27 Cluster: Proteasome subunit beta type-6 precursor;
n=14; Magnoliophyta|Rep: Proteasome subunit beta type-6
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 233
Score = 36.3 bits (80), Expect = 0.72
Identities = 18/66 (27%), Positives = 34/66 (51%)
Frame = +1
Query: 205 SPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQY 384
+P + TT+IGV ++ G V+ D+ S G R ++ ++ D + + G AD Q
Sbjct: 7 APHSMGTTIIGVTYNGGVVLGADSRTSTGMYVANRASDKITQLTDNVYVCRSGSAADSQV 66
Query: 385 LKDIIQ 402
+ D ++
Sbjct: 67 VSDYVR 72
>UniRef50_A1UHS7 Cluster: 20S proteasome, A and B subunits; n=19;
Corynebacterineae|Rep: 20S proteasome, A and B subunits
- Mycobacterium sp. (strain KMS)
Length = 304
Score = 35.9 bits (79), Expect = 0.96
Identities = 17/50 (34%), Positives = 26/50 (52%)
Frame = +1
Query: 223 TTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYA 372
TT++ +KF G V+AGD + G++ RD +V +D G G A
Sbjct: 66 TTIVALKFPGGVVMAGDRRATQGNMIASRDVQKVYITDDYTATGIAGTAA 115
>UniRef50_Q8I0U7 Cluster: Proteasome, putative; n=5; Plasmodium|Rep:
Proteasome, putative - Plasmodium falciparum (isolate
3D7)
Length = 282
Score = 35.9 bits (79), Expect = 0.96
Identities = 18/66 (27%), Positives = 38/66 (57%)
Frame = +1
Query: 205 SPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQY 384
+PI+ TT+IG+ +D G ++A D+ S G+ + ++ ++N+ + + G A Q
Sbjct: 25 TPISDGTTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQK 84
Query: 385 LKDIIQ 402
+ +II+
Sbjct: 85 IIEIIK 90
>UniRef50_Q6RKE3 Cluster: Polyketide synthase; n=2; Fungi/Metazoa
group|Rep: Polyketide synthase - Cochliobolus
heterostrophus (Drechslera maydis)
Length = 2528
Score = 35.9 bits (79), Expect = 0.96
Identities = 19/51 (37%), Positives = 25/51 (49%)
Frame = +1
Query: 58 TMAFMGDTMNPTPLWQNGPSPGAFYNFPGNASTIAPSRHGVQDFTAHSASP 210
T+ + DT N P + P+P P +A+T PSRH V D ASP
Sbjct: 1726 TLEKLLDTANSAPAPRKDPAPRTDSAPPKHATTAVPSRHAVPDLLPADASP 1776
>UniRef50_UPI0000DB7B4D Cluster: PREDICTED: similar to Dicer-1
CG4792-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to Dicer-1 CG4792-PA - Apis mellifera
Length = 1838
Score = 35.5 bits (78), Expect = 1.3
Identities = 29/76 (38%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Frame = -2
Query: 588 CSQFINSSEKGF---TILNTGNHIAVPEGIHLAPLVVEDTSQPAVQRTGLELETISNTAL 418
C + IN+S+ F TIL+ N VP I LA + T +P R GLE+E + NT
Sbjct: 133 CHKSINNSQLKFILQTILSCNN---VPRIIGLAVPLFNLTQEPG--RLGLEIEKVENTFQ 187
Query: 417 INDFLLNDILQILKIS 370
+DIL IL+ S
Sbjct: 188 CEVETASDILSILRYS 203
>UniRef50_Q8T8U1 Cluster: Proteasome subunit beta type; n=1;
Drosophila melanogaster|Rep: Proteasome subunit beta
type - Drosophila melanogaster (Fruit fly)
Length = 215
Score = 35.5 bits (78), Expect = 1.3
Identities = 36/160 (22%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
T++GVK ++A DT+ + ++ + + +++D ++ GD D D I +
Sbjct: 3 TILGVKGTDFIILASDTMRNKSAMWLDDEVRKTHRISDYCMMSTAGDGGDCLKFSDFILR 62
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQD--GEPFLGAVDK 579
+D + +G L R ++ R L + K D + ++ G D P L +D
Sbjct: 63 N-MDLYKITNGYDLTVRGAVHFIRRHL-SAYLKSDCTFQVSLLVGGYDLTSGPELHYIDY 120
Query: 580 LGTAYEDAVISNGLGAYMATPLLRDAVDKGPLDQETAIAV 699
LG + +G TP+L + K +D + A V
Sbjct: 121 LGNSVPVRYGGHGAAMNFCTPILEEFY-KPDMDTQAAYDV 159
>UniRef50_UPI0000E47CE3 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 229
Score = 35.1 bits (77), Expect = 1.7
Identities = 17/62 (27%), Positives = 33/62 (53%)
Frame = +1
Query: 223 TTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQ 402
TT +G KF+ G VIA D+ + G + +V+++N +L G AD + + ++
Sbjct: 71 TTTLGFKFEHGVVIAVDSRATAGPYIASQSVKKVIEINPYLLGTMAGGAADCAFWERVLA 130
Query: 403 QK 408
++
Sbjct: 131 EQ 132
>UniRef50_Q4UIA0 Cluster: Proteasome subunit beta type; n=8;
Aconoidasida|Rep: Proteasome subunit beta type -
Theileria annulata
Length = 271
Score = 35.1 bits (77), Expect = 1.7
Identities = 17/58 (29%), Positives = 30/58 (51%)
Frame = +1
Query: 211 ITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQY 384
+ T TT+ GV V+A DT + G + ++C ++ K++D I G AD ++
Sbjct: 37 LKTGTTICGVMGRDSVVLAADTRATQGIIVADKNCSKLHKISDNIYCAGAGVAADLEH 94
>UniRef50_Q1D018 Cluster: Beta-ketoacyl synthase family protein;
n=2; Cystobacterineae|Rep: Beta-ketoacyl synthase family
protein - Myxococcus xanthus (strain DK 1622)
Length = 522
Score = 34.7 bits (76), Expect = 2.2
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Frame = +1
Query: 178 VQDFTAHSASPITTTTTVIGVKFDKGCVIA----GDTLGSYGSLARFRDCPRVMKVNDLI 345
++ FTA P+ +GV D +I G TL +LA P M DL
Sbjct: 353 LEHFTAKGFKPLGMEPIAVGVTADADHIITPSKEGPTLAIREALAAAGCAPEDMGSWDLH 412
Query: 346 LLGCGGDYADFQYLKDIIQQKII 414
GDY + Q L+D++ ++++
Sbjct: 413 ATATPGDYLEVQNLRDVLPEQVL 435
>UniRef50_Q7DLS1 Cluster: Proteasome subunit beta type-7-B
precursor; n=28; Eukaryota|Rep: Proteasome subunit beta
type-7-B precursor - Arabidopsis thaliana (Mouse-ear
cress)
Length = 274
Score = 34.7 bits (76), Expect = 2.2
Identities = 15/67 (22%), Positives = 34/67 (50%)
Frame = +1
Query: 211 ITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLK 390
+ T TT++G+ F G ++ DT + G + ++C ++ + I G AD + +
Sbjct: 36 LKTGTTIVGLIFKDGVILGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADTEAVT 95
Query: 391 DIIQQKI 411
D++ ++
Sbjct: 96 DMVSSQL 102
>UniRef50_Q4UER7 Cluster: Proteasome subunit y, putative; n=4;
Piroplasmida|Rep: Proteasome subunit y, putative -
Theileria annulata
Length = 294
Score = 34.3 bits (75), Expect = 2.9
Identities = 19/60 (31%), Positives = 30/60 (50%)
Frame = +1
Query: 223 TTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQ 402
TT+IG+KF G ++ D S G + R ++ ++ I + G AD Q L II+
Sbjct: 69 TTIIGMKFMDGVILVADGRTSSGQIVANRVARKITRILPNIFMLRSGSAADSQTLSTIIR 128
>UniRef50_P40304 Cluster: Proteasome subunit beta type-1 precursor;
n=6; Endopterygota|Rep: Proteasome subunit beta type-1
precursor - Drosophila melanogaster (Fruit fly)
Length = 235
Score = 34.3 bits (75), Expect = 2.9
Identities = 34/156 (21%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
Frame = +1
Query: 226 TVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDIIQQ 405
+++ + D VIA DT S G R ++ K++ +LG G +AD L I+
Sbjct: 31 SIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWADTLSLTGSIKV 90
Query: 406 KIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGI-QDGEPFLGAVDKL 582
++ + ++ L+ +YN+R P + S ++AGI +G+ + + D +
Sbjct: 91 RMQSYEHT-HLRTMTTEAVAQMLSIAMYNRR--FFPYYVSNILAGIDNEGKGVVYSYDPI 147
Query: 583 GTAYEDAVISNGLGAYMATPLLRDAVDKGPLDQETA 690
G + + G + P+L + + ++ E A
Sbjct: 148 GHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDA 183
>UniRef50_P28065 Cluster: Proteasome subunit beta type-9 precursor;
n=79; Eumetazoa|Rep: Proteasome subunit beta type-9
precursor - Homo sapiens (Human)
Length = 219
Score = 33.9 bits (74), Expect = 3.9
Identities = 19/65 (29%), Positives = 32/65 (49%)
Frame = +1
Query: 202 ASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQ 381
A + T TT++ V+FD G V+ D+ S G R ++ +++ I G AD Q
Sbjct: 14 AGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQ 73
Query: 382 YLKDI 396
+ D+
Sbjct: 74 AVADM 78
>UniRef50_P34286 Cluster: Proteasome subunit beta type-1; n=2;
Caenorhabditis|Rep: Proteasome subunit beta type-1 -
Caenorhabditis elegans
Length = 258
Score = 33.9 bits (74), Expect = 3.9
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 2/146 (1%)
Frame = +1
Query: 217 TTTTVIGVKFDKGCVIAGDTLGSYGSLARF-RDCPRVMKVNDLILLGCGGDYADFQYLKD 393
+T + G F ++A DT + + RD ++ +ND I+L G Y D LK
Sbjct: 53 STCAISGENF---AIVASDTRMTQNDINILTRDAEKIQILNDNIILTTSGFYGDVLQLKK 109
Query: 394 IIQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQD-GEPFLGA 570
++Q ++ R + L+R LY +R P + ++AGI + G+ + +
Sbjct: 110 VLQSRLHKYR-FDYRSDMSVDLCAELLSRNLYYRR--FFPYYTGAILAGIDEHGKGAVFS 166
Query: 571 VDKLGTAYEDAVISNGLGAYMATPLL 648
D +G ++G M P L
Sbjct: 167 YDPIGCIERLGYSASGAAEPMIIPFL 192
>UniRef50_Q4RM53 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF15019, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 567
Score = 33.1 bits (72), Expect = 6.7
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = -1
Query: 688 QFLGPEVLYPLRP-SVEESP-CKLLARSRSQHLHRLFPIYQQLRERVHHPEYRQPHSCSR 515
Q+ P L PL P S++ + C L R + LH+ RVH P++R PH C
Sbjct: 347 QYCEPIPLPPLAPLSLQVTLLCSLWHRPK---LHQWLVPQPHHPHRVHRPQWRCPHPCLL 403
Query: 514 GDPSCSSCCRGHESTSSAENG 452
P G + +SS+ G
Sbjct: 404 RCPLAEGLLGGFQESSSSPQG 424
>UniRef50_Q2J9Q3 Cluster: 20S proteasome, A and B subunits; n=23;
Actinomycetales|Rep: 20S proteasome, A and B subunits -
Frankia sp. (strain CcI3)
Length = 304
Score = 33.1 bits (72), Expect = 6.7
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +1
Query: 223 TTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGG 363
TT++ V F G ++AGD + G + RD +V +D +G G
Sbjct: 83 TTIVAVAFPGGVIMAGDRRATQGHMIAQRDVEKVHHADDYSCVGYAG 129
>UniRef50_UPI0000DD7CB5 Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 276
Score = 32.7 bits (71), Expect = 8.9
Identities = 15/41 (36%), Positives = 20/41 (48%)
Frame = -1
Query: 574 QQLRERVHHPEYRQPHSCSRGDPSCSSCCRGHESTSSAENG 452
QQ+R P + +PHS + P S C + H AENG
Sbjct: 26 QQVRSVCARPAWGRPHSPQQLAPGLSRCTQPHPEPEDAENG 66
>UniRef50_UPI0000D55E14 Cluster: PREDICTED: similar to CG5912-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG5912-PA - Tribolium castaneum
Length = 1580
Score = 32.7 bits (71), Expect = 8.9
Identities = 13/38 (34%), Positives = 21/38 (55%)
Frame = -1
Query: 601 HLHRLFPIYQQLRERVHHPEYRQPHSCSRGDPSCSSCC 488
HL P+Y Q+ + P ++PH+C+R + CS C
Sbjct: 278 HLDYTVPMYIQVYNELRQP--KRPHACARNNGGCSHLC 313
>UniRef50_A0D0W1 Cluster: Chromosome undetermined scaffold_33, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_33,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 761
Score = 32.7 bits (71), Expect = 8.9
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = -2
Query: 498 PLVVEDTSQPAVQRTGLELETISNTALINDFLLNDILQILKISIVSS 358
P+ + + P Q +E+E I N L ++ LLND + +L+ IVS+
Sbjct: 153 PIEFNEKADPRFQIKKVEIEHILNKCLFSEVLLNDSILLLQDKIVSA 199
>UniRef50_Q9JMS5 Cluster: Uncharacterized protein yuaO precursor; n=1;
Escherichia coli K12|Rep: Uncharacterized protein yuaO
precursor - Escherichia coli (strain K12)
Length = 1758
Score = 32.7 bits (71), Expect = 8.9
Identities = 20/74 (27%), Positives = 34/74 (45%)
Frame = +1
Query: 181 QDFTAHSASPITTTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCG 360
+D+ AH S + + G K + GDT GS G + ++ K D++L+
Sbjct: 1324 KDYVAHDGSGVQFG--IFGQKEADVMHVKGDTSGSSGIVVTTNSKNKIKKGGDILLVEVN 1381
Query: 361 GDYADFQYLKDIIQ 402
GD + YL +I+
Sbjct: 1382 GDSSGSFYLNSLIK 1395
>UniRef50_Q99436 Cluster: Proteasome subunit beta type-7 precursor;
n=44; Fungi/Metazoa group|Rep: Proteasome subunit beta
type-7 precursor - Homo sapiens (Human)
Length = 277
Score = 32.7 bits (71), Expect = 8.9
Identities = 28/146 (19%), Positives = 62/146 (42%)
Frame = +1
Query: 217 TTTTVIGVKFDKGCVIAGDTLGSYGSLARFRDCPRVMKVNDLILLGCGGDYADFQYLKDI 396
T TT+ GV + G V+ DT + G + ++C ++ ++ I G AD +
Sbjct: 42 TGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQL 101
Query: 397 IQQKIIDERCVGDGLQLKPRSLHCWLTRVLYNKRSKMDPLWNSYVVAGIQDGEPFLGAVD 576
I ++ + G + + + L ++L+ + + + V+ G+ P L ++
Sbjct: 102 ISSN-LELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGA---ALVLGGVDVTGPHLYSIY 157
Query: 577 KLGTAYEDAVISNGLGAYMATPLLRD 654
G+ + ++ G G+ A + D
Sbjct: 158 PHGSTDKLPYVTMGSGSLAAMAVFED 183
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 729,840,896
Number of Sequences: 1657284
Number of extensions: 15553567
Number of successful extensions: 50374
Number of sequences better than 10.0: 86
Number of HSP's better than 10.0 without gapping: 47566
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 50301
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55371905986
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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