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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= I10A02NGRL0001_A10
         (390 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA ...   147   6e-35
UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30; Coelom...   129   2e-29
UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to 3-hydroxya...   129   2e-29
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve...   111   5e-24
UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|R...   105   2e-22
UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN ful...    96   2e-19
UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    83   1e-15
UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2...    80   2e-14
UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5; Alphaproteobacter...    73   2e-12
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ...    73   3e-12
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3...    71   8e-12
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6...    71   8e-12
UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3; ...    71   8e-12
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A...    69   2e-11
UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    69   3e-11
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl...    69   4e-11
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    64   7e-10
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N...    64   9e-10
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas...    64   9e-10
UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3; ...    63   2e-09
UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    62   3e-09
UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A...    62   3e-09
UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1; Bre...    62   4e-09
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3...    62   5e-09
UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    62   5e-09
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A...    61   6e-09
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati...    60   1e-08
UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2...    60   1e-08
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2...    60   2e-08
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m...    59   3e-08
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c...    59   3e-08
UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P...    59   3e-08
UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas...    58   5e-08
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A...    58   5e-08
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3...    58   6e-08
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4...    57   1e-07
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    56   2e-07
UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1; ...    56   2e-07
UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome. prec...    56   2e-07
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2...    56   2e-07
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c...    56   2e-07
UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4; S...    56   3e-07
UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; B...    55   4e-07
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2...    55   4e-07
UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA dehyd...    55   6e-07
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S...    55   6e-07
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ...    54   7e-07
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S...    54   7e-07
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5...    54   1e-06
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5...    54   1e-06
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati...    54   1e-06
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    54   1e-06
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2...    54   1e-06
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec...    53   2e-06
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas...    53   2e-06
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    53   2e-06
UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas...    53   2e-06
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H...    53   2e-06
UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ...    52   3e-06
UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec...    52   4e-06
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5...    52   5e-06
UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;...    52   5e-06
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    52   5e-06
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge...    52   5e-06
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8...    51   7e-06
UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,...    51   9e-06
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    51   9e-06
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    51   9e-06
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4...    50   1e-05
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu...    50   1e-05
UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    50   1e-05
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B...    50   2e-05
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    50   2e-05
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3...    50   2e-05
UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    50   2e-05
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c...    50   2e-05
UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A...    50   2e-05
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1...    50   2e-05
UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ...    50   2e-05
UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec...    50   2e-05
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs...    50   2e-05
UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    49   3e-05
UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    49   3e-05
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ...    49   3e-05
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:...    49   4e-05
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P...    49   4e-05
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr...    49   4e-05
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati...    49   4e-05
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P...    48   5e-05
UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2...    48   5e-05
UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified ...    48   5e-05
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro...    48   6e-05
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    48   6e-05
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen...    48   9e-05
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd...    47   1e-04
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ...    47   1e-04
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C...    47   1e-04
UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:...    47   1e-04
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA...    47   1e-04
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re...    47   1e-04
UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA hydratase/3-hydroxya...    47   1e-04
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;...    47   1e-04
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas...    47   1e-04
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    47   1e-04
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi...    47   1e-04
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    46   2e-04
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ...    46   2e-04
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2...    46   3e-04
UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    46   3e-04
UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1; ...    46   3e-04
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec...    46   3e-04
UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ...    45   5e-04
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec...    45   5e-04
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy...    45   6e-04
UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    45   6e-04
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB...    45   6e-04
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun...    45   6e-04
UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep...    44   8e-04
UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ...    44   8e-04
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n...    44   0.001
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ...    44   0.001
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5...    44   0.001
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    44   0.001
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    44   0.001
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ...    44   0.001
UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    44   0.001
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C...    44   0.001
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    43   0.002
UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    43   0.002
UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    43   0.002
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2...    43   0.002
UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3; Lacto...    42   0.003
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ...    42   0.003
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    42   0.003
UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella ve...    42   0.003
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3...    42   0.004
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ...    42   0.004
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3...    42   0.004
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec...    42   0.006
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    42   0.006
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    41   0.007
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G...    41   0.007
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C...    41   0.007
UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    41   0.007
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    41   0.007
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit...    41   0.007
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A...    41   0.007
UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44; ...    41   0.010
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    41   0.010
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P...    41   0.010
UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    41   0.010
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    41   0.010
UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1; A...    40   0.013
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1...    40   0.013
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    40   0.013
UniRef50_A2QA05 Cluster: Catalytic activity:; n=4; Trichocomacea...    40   0.013
UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3; Achol...    40   0.013
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ...    40   0.017
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ...    40   0.017
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    40   0.017
UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65; cell...    40   0.023
UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ...    39   0.030
UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P...    39   0.030
UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost...    39   0.030
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n...    39   0.040
UniRef50_Q11E55 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    39   0.040
UniRef50_A6LMV1 Cluster: Putative uncharacterized protein precur...    39   0.040
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    39   0.040
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    39   0.040
UniRef50_A3LNF8 Cluster: Kynurenine 3-monooxygenase, mitochondri...    39   0.040
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9...    39   0.040
UniRef50_Q83EI9 Cluster: Thiamine biosynthesis oxidoreductase Th...    38   0.052
UniRef50_Q6MHW5 Cluster: Glucose-inhibited division protein; n=1...    38   0.052
UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD bi...    38   0.052
UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|R...    38   0.052
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    38   0.052
UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13; Baci...    38   0.052
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ...    38   0.069
UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H...    38   0.069
UniRef50_Q2GH13 Cluster: FAD-dependent oxidoreductase; n=6; Anap...    38   0.069
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge...    38   0.069
UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine nucleotide-dis...    38   0.091
UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1; C...    38   0.091
UniRef50_A6TSA3 Cluster: Amine oxidase; n=1; Alkaliphilus metall...    38   0.091
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    38   0.091
UniRef50_A3XPY3 Cluster: Putative uncharacterized protein; n=1; ...    38   0.091
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V...    38   0.091
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    38   0.091
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;...    38   0.091
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ...    38   0.091
UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4; Thermococ...    38   0.091
UniRef50_P38169 Cluster: Kynurenine 3-monooxygenase; n=4; Saccha...    38   0.091
UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;...    37   0.12 
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R...    37   0.12 
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ...    37   0.12 
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema...    37   0.12 
UniRef50_Q485S6 Cluster: Putative D-amino acid dehydrogenase, sm...    37   0.16 
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    37   0.16 
UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA dehy...    37   0.16 
UniRef50_Q0TSZ8 Cluster: Transcriptional regulator, MarR family;...    37   0.16 
UniRef50_Q1FP37 Cluster: NADH:flavin oxidoreductase/NADH oxidase...    36   0.21 
UniRef50_A3D4X7 Cluster: FAD dependent oxidoreductase; n=3; Shew...    36   0.21 
UniRef50_A1SV61 Cluster: FAD dependent oxidoreductase precursor;...    36   0.21 
UniRef50_Q6KCB6 Cluster: Dihydrolipoyl dehydrogenase; n=8; Plasm...    36   0.21 
UniRef50_A7TI21 Cluster: Putative uncharacterized protein; n=1; ...    36   0.21 
UniRef50_Q82W31 Cluster: Phosphoribosylaminoimidazole carboxylas...    36   0.28 
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena...    36   0.28 
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term...    36   0.28 
UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    36   0.28 
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ...    36   0.28 
UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4; Trichoco...    36   0.28 
UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3; Cl...    36   0.37 
UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid aminot...    36   0.37 
UniRef50_A6M0T5 Cluster: Amine oxidase; n=6; Clostridium|Rep: Am...    36   0.37 
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    36   0.37 
UniRef50_A0UYP0 Cluster: Amine oxidase; n=1; Clostridium cellulo...    36   0.37 
UniRef50_Q4J9Z6 Cluster: Conserved Crenarchaeal protein; n=3; Su...    36   0.37 
UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;...    35   0.49 
UniRef50_Q8YKN8 Cluster: Zeta-carotene desaturase; n=4; Bacteria...    35   0.49 
UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7; Bacte...    35   0.49 
UniRef50_Q6MDA0 Cluster: Probable soluble pyridine nucleotide tr...    35   0.49 
UniRef50_Q6FF29 Cluster: Putative oxidoreductase; putative flavo...    35   0.49 
UniRef50_Q6A6B6 Cluster: Pyridine nucleotide-disulphide oxidored...    35   0.49 
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    35   0.49 
UniRef50_Q8GP50 Cluster: Eps11H; n=13; Lactobacillales|Rep: Eps1...    35   0.49 
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;...    35   0.49 
UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex,...    35   0.49 
UniRef50_A7FX66 Cluster: Pyridine nucleotide-disulphide oxidored...    35   0.49 
UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ac...    35   0.49 
UniRef50_Q8TWI7 Cluster: UDP-N-acetylmuramoylalanine-D-glutamate...    35   0.49 
UniRef50_Q9X0U4 Cluster: Glutamate synthase, beta subunit; n=5; ...    35   0.64 
UniRef50_Q3AEV2 Cluster: Prephenate dehydrogenase; n=1; Carboxyd...    35   0.64 
UniRef50_Q2RJ81 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding ...    35   0.64 
UniRef50_Q2JD10 Cluster: Prephenate dehydrogenase; n=4; Frankia|...    35   0.64 
UniRef50_Q1MF67 Cluster: Putative D-amino acid dehydrogenase pre...    35   0.64 
UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    35   0.64 
UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    35   0.64 
UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    35   0.64 
UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13; c...    35   0.64 
UniRef50_Q4Q3S6 Cluster: Enoyl-CoA hydratase/Enoyl-CoA isomerase...    35   0.64 
UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7; Streptoco...    35   0.64 
UniRef50_Q4FKW7 Cluster: D-amino-acid dehydrogenase small chain;...    34   0.85 
UniRef50_Q2LWM5 Cluster: Zinc-binding dehydrogenase; n=1; Syntro...    34   0.85 
UniRef50_Q1IUZ3 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ...    34   0.85 
UniRef50_Q1IMR6 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ...    34   0.85 
UniRef50_Q1FMM1 Cluster: Dihydrolipoyl dehydrogenase; n=2; Clost...    34   0.85 
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1...    34   0.85 
UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A...    34   0.85 
UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1; ...    34   0.85 
UniRef50_A5V9L0 Cluster: FAD dependent oxidoreductase precursor;...    34   0.85 
UniRef50_A7RTC7 Cluster: Predicted protein; n=1; Nematostella ve...    34   0.85 
UniRef50_Q0UJN7 Cluster: Predicted protein; n=1; Phaeosphaeria n...    34   0.85 
UniRef50_P12045 Cluster: Phosphoribosylaminoimidazole carboxylas...    34   0.85 
UniRef50_Q9JXF8 Cluster: Glycine oxidase ThiO; n=4; Neisseria|Re...    34   1.1  
UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8; My...    34   1.1  
UniRef50_Q8R9D9 Cluster: Dihydrolipoyl dehydrogenase; n=3; Therm...    34   1.1  
UniRef50_Q8F125 Cluster: Cell-division inhibitor; n=3; Bacteria|...    34   1.1  
UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas...    34   1.1  
UniRef50_Q39TK4 Cluster: NADH:flavin oxidoreductase/NADH oxidase...    34   1.1  
UniRef50_Q4AI87 Cluster: FAD-dependent pyridine nucleotide-disul...    34   1.1  
UniRef50_Q2BN82 Cluster: D-amino acid dehydrogenase, small subun...    34   1.1  
UniRef50_Q0F8T2 Cluster: Salicylate hydroxylase; n=1; alpha prot...    34   1.1  
UniRef50_A4XMY3 Cluster: Prephenate dehydrogenase; n=1; Caldicel...    34   1.1  
UniRef50_A0M4X2 Cluster: Kynurenine-3-monooxygenase-like protein...    34   1.1  
UniRef50_Q8TZS4 Cluster: Glutamate synthase; n=78; cellular orga...    34   1.1  
UniRef50_Q8RC01 Cluster: UDP-N-acetyl-D-mannosaminuronate dehydr...    33   1.5  
UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1...    33   1.5  
UniRef50_Q5ZV78 Cluster: Mercuric reductase; n=5; Legionella pne...    33   1.5  
UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1; Mycop...    33   1.5  
UniRef50_Q31JD0 Cluster: Thiamine biosynthesis oxidoreductase; n...    33   1.5  
UniRef50_Q0C0V2 Cluster: Oxidoreductase, FAD-binding; n=2; Prote...    33   1.5  
UniRef50_Q0B0P7 Cluster: NADP oxidoreductase, coenzyme F420-depe...    33   1.5  
UniRef50_A3EPX8 Cluster: Dihydrolipoyl dehydrogenase; n=1; Lepto...    33   1.5  
UniRef50_A5UMG8 Cluster: Cell wall biosynthesis protein, MurD-li...    33   1.5  
UniRef50_A3DNK1 Cluster: Dihydrolipoamide dehydrogenase; n=1; St...    33   1.5  
UniRef50_UPI0000510280 Cluster: COG1249: Pyruvate/2-oxoglutarate...    33   2.0  
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute...    33   2.0  
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge...    33   2.0  
UniRef50_Q87Q19 Cluster: D-amino acid dehydrogenase, small subun...    33   2.0  
UniRef50_Q5H1Q2 Cluster: Putative uncharacterized protein; n=6; ...    33   2.0  
UniRef50_Q5FJ98 Cluster: Peroxidase; n=8; Lactobacillales|Rep: P...    33   2.0  
UniRef50_Q9JPB5 Cluster: Methoxyneurosporene dehydrogenase; n=5;...    33   2.0  
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci...    33   2.0  
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge...    33   2.0  
UniRef50_Q021A6 Cluster: FAD-dependent pyridine nucleotide-disul...    33   2.0  
UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    33   2.0  
UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin...    33   2.0  
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar...    33   2.0  
UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid dehydro...    33   2.0  
UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide transhydrog...    33   2.0  
UniRef50_A4CCE3 Cluster: Putative D-amino acid dehydrogenase, sm...    33   2.0  
UniRef50_A4A0Z6 Cluster: Putative transmemembrane reductase oxid...    33   2.0  
UniRef50_A1HBS6 Cluster: 2-polyprenyl-6-methoxyphenol hydroxylas...    33   2.0  
UniRef50_A0YKN9 Cluster: Putative secreted oxidoreductase; n=1; ...    33   2.0  
UniRef50_A0YDQ2 Cluster: NADP oxidoreductase, coenzyme F420-depe...    33   2.0  
UniRef50_O28680 Cluster: Putative uncharacterized protein; n=1; ...    33   2.0  
UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide ...    33   2.0  
UniRef50_Q9FC18 Cluster: 2,4-dienoyl-CoA reductase [NADPH]; n=5;...    33   2.6  
UniRef50_Q92A98 Cluster: Lin2024 protein; n=13; Listeria|Rep: Li...    33   2.6  
UniRef50_Q8ESA1 Cluster: Phosphoribosylaminoimidazole carboxylas...    33   2.6  
UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus pla...    33   2.6  
UniRef50_Q5WI78 Cluster: NADH peroxidase; n=1; Bacillus clausii ...    33   2.6  
UniRef50_Q5L3D7 Cluster: Phosphoribosylaminoimidazole carboxylas...    33   2.6  
UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H...    33   2.6  
UniRef50_P73059 Cluster: Mercuric reductase; n=11; Bacteria|Rep:...    33   2.6  
UniRef50_Q222Q6 Cluster: FAD dependent oxidoreductase precursor;...    33   2.6  
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;...    33   2.6  
UniRef50_Q1YK26 Cluster: Phosphoribosylaminoimidazole carboxylas...    33   2.6  
UniRef50_Q1Q5P1 Cluster: Similar to NAD(P) oxidoreductase, FAD-c...    33   2.6  
UniRef50_Q1NYB6 Cluster: FAD-dependent pyridine nucleotide-disul...    33   2.6  
UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi...    33   2.6  
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R...    33   2.6  
UniRef50_A7DM30 Cluster: Multi-sensor hybrid histidine kinase; n...    33   2.6  
UniRef50_A7B6H9 Cluster: Putative uncharacterized protein; n=1; ...    33   2.6  
UniRef50_A6SY70 Cluster: Uncharacterized conserved protein; n=2;...    33   2.6  
UniRef50_A3PFJ2 Cluster: NAD binding site:D-amino acid oxidase; ...    33   2.6  
UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec...    33   2.6  
UniRef50_A7PXU5 Cluster: Chromosome chr15 scaffold_37, whole gen...    33   2.6  
UniRef50_Q5CRF9 Cluster: Alpha amylase; n=2; Cryptosporidium|Rep...    33   2.6  
UniRef50_A7EL57 Cluster: Putative uncharacterized protein; n=1; ...    33   2.6  
UniRef50_A4YI59 Cluster: Pyridine nucleotide-disulphide oxidored...    33   2.6  
UniRef50_P54533 Cluster: Dihydrolipoyl dehydrogenase; n=41; Firm...    33   2.6  
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar...    33   2.6  
UniRef50_Q9PK36 Cluster: Putative uncharacterized protein; n=1; ...    32   3.4  
UniRef50_Q98N90 Cluster: Mll0243 protein; n=1; Mesorhizobium lot...    32   3.4  
UniRef50_Q8XT97 Cluster: Putative type III effector protein; n=2...    32   3.4  
UniRef50_Q7UQS2 Cluster: Phosphoribosylaminoimidazole carboxylas...    32   3.4  
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro...    32   3.4  
UniRef50_Q6VXQ2 Cluster: NOXase; n=1; Enterococcus faecium|Rep: ...    32   3.4  
UniRef50_Q3IBS8 Cluster: Iron-sulfur-binding protein, glutamate ...    32   3.4  
UniRef50_Q18RI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n...    32   3.4  
UniRef50_Q11MN5 Cluster: FAD dependent oxidoreductase; n=2; Meso...    32   3.4  
UniRef50_Q11LC6 Cluster: FAD dependent oxidoreductase precursor;...    32   3.4  
UniRef50_Q08VR6 Cluster: NADP oxidoreductase, coenzyme f420-depe...    32   3.4  
UniRef50_Q03CK2 Cluster: Predicted dinucleotide-binding enzyme; ...    32   3.4  
UniRef50_A7GZ57 Cluster: NADP oxidoreductase, coenzyme f420-depe...    32   3.4  
UniRef50_A6NZT3 Cluster: Putative uncharacterized protein; n=2; ...    32   3.4  
UniRef50_A5WGP4 Cluster: FAD dependent oxidoreductase; n=1; Psyc...    32   3.4  
UniRef50_A5GED6 Cluster: NADH:flavin oxidoreductase/NADH oxidase...    32   3.4  
UniRef50_A5FR09 Cluster: FAD-dependent pyridine nucleotide-disul...    32   3.4  
UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR...    32   3.4  
UniRef50_A4M0G7 Cluster: 2-dehydropantoate 2-reductase precursor...    32   3.4  
UniRef50_A0LGG9 Cluster: FAD-dependent pyridine nucleotide-disul...    32   3.4  
UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus ter...    32   3.4  
UniRef50_Q02670 Cluster: ORF22; n=1; Podospora anserina|Rep: ORF...    32   3.4  
UniRef50_A4R025 Cluster: Putative uncharacterized protein; n=1; ...    32   3.4  
UniRef50_Q8PXP4 Cluster: UDP-N-acetyl-D-mannosamine 6-dehydrogen...    32   3.4  
UniRef50_Q64C49 Cluster: Formate dehydrogenase beta subunit; n=1...    32   3.4  
UniRef50_Q6D8S1 Cluster: Nitric oxide reductase FlRd-NAD(+) redu...    32   3.4  
UniRef50_O66913 Cluster: tRNA uridine 5-carboxymethylaminomethyl...    32   3.4  
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ...    32   4.5  
UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ...    32   4.5  
UniRef50_UPI00006A011C Cluster: mucin 16 (MUC16), mRNA; n=3; Xen...    32   4.5  
UniRef50_Q8G3X6 Cluster: Possible class I pyridine nucleotide-di...    32   4.5  
UniRef50_Q8CX86 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ...    32   4.5  
UniRef50_Q89ZR6 Cluster: NADPH-dependent glutamate synthase smal...    32   4.5  
UniRef50_Q88YJ8 Cluster: NADH oxidase; n=8; Lactobacillaceae|Rep...    32   4.5  
UniRef50_Q68VU4 Cluster: Dihydrolipoyl dehydrogenase; n=11; Rick...    32   4.5  
UniRef50_Q63LP0 Cluster: Cation-transporting ATPase; n=51; Prote...    32   4.5  
UniRef50_Q8KRG4 Cluster: NADH oxidase; n=14; Bacteria|Rep: NADH ...    32   4.5  
UniRef50_Q41B40 Cluster: Similar to Phytoene dehydrogenase and r...    32   4.5  
UniRef50_Q1DAE6 Cluster: NADP oxidoreductase, coenzyme F420-depe...    32   4.5  
UniRef50_Q11PG6 Cluster: Pyridine nucleotide-disulphide-related ...    32   4.5  
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase...    32   4.5  
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1...    32   4.5  
UniRef50_Q090H7 Cluster: Soluble pyridine nucleotide transhydrog...    32   4.5  
UniRef50_Q04KN1 Cluster: UDP-N-acetyl-D-mannosaminuronic acid de...    32   4.5  
UniRef50_A7BS25 Cluster: Phosphoribosylaminoimidazole carboxylas...    32   4.5  
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ...    32   4.5  
UniRef50_A6GGV0 Cluster: Prephenate dehydrogenase; n=1; Plesiocy...    32   4.5  
UniRef50_A4YNF9 Cluster: Oxidoreductase; (Flavoprotein subunit; ...    32   4.5  
UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1; ...    32   4.5  
UniRef50_A3VIL7 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy...    32   4.5  
UniRef50_A0Q826 Cluster: Dihydrolipoamide dehydrogenase; n=7; Fr...    32   4.5  
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro...    32   4.5  
UniRef50_A5BGL0 Cluster: Putative uncharacterized protein; n=1; ...    32   4.5  
UniRef50_A0DJ73 Cluster: Chromosome undetermined scaffold_52, wh...    32   4.5  
UniRef50_Q8TJW5 Cluster: Putative uncharacterized protein; n=1; ...    32   4.5  
UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A...    32   4.5  
UniRef50_A4YFQ3 Cluster: Pyridine nucleotide-disulphide oxidored...    32   4.5  
UniRef50_P79076 Cluster: Pyranose 2-oxidase precursor; n=7; Agar...    32   4.5  
UniRef50_Q6TGQ9 Cluster: L-amino-acid oxidase precursor; n=6; Sa...    32   4.5  
UniRef50_UPI0001597852 Cluster: hypothetical protein RBAM_031240...    31   6.0  
UniRef50_Q9RW59 Cluster: Dehydrogenase, putative; n=2; Deinococc...    31   6.0  
UniRef50_Q983V4 Cluster: Salicylate hydroxylase; n=2; Mesorhizob...    31   6.0  
UniRef50_Q97L02 Cluster: NADPH-dependent glutamate synthase beta...    31   6.0  
UniRef50_Q97DR4 Cluster: NADH oxidase; n=1; Clostridium acetobut...    31   6.0  
UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A...    31   6.0  
UniRef50_Q8G588 Cluster: Phosphoribosylaminoimidazole carboxylas...    31   6.0  
UniRef50_Q8E285 Cluster: Pyridine nucleotide-disulphide oxidored...    31   6.0  
UniRef50_Q88U21 Cluster: Phosphoribosylaminoimidazole carboxylas...    31   6.0  
UniRef50_Q7MTD4 Cluster: Glutamate synthase, small subunit; n=20...    31   6.0  
UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9...    31   6.0  
UniRef50_Q7CTP1 Cluster: AGR_L_1811p; n=2; Agrobacterium tumefac...    31   6.0  
UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P...    31   6.0  
UniRef50_Q12II5 Cluster: FAD-dependent pyridine nucleotide-disul...    31   6.0  
UniRef50_Q036G7 Cluster: Lactate dehydrogenase related 2-hydroxy...    31   6.0  
UniRef50_P77907 Cluster: Formate dehydrogenase beta subunit; n=2...    31   6.0  
UniRef50_A7B6D3 Cluster: Putative uncharacterized protein; n=1; ...    31   6.0  
UniRef50_A5WHA9 Cluster: NADH:flavin oxidoreductase/NADH oxidase...    31   6.0  
UniRef50_A4EA08 Cluster: Putative uncharacterized protein; n=2; ...    31   6.0  
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2...    31   6.0  
UniRef50_A2SG82 Cluster: Thiamine biosynthesis oxidoreductase Th...    31   6.0  
UniRef50_A1WMY0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b...    31   6.0  
UniRef50_A0YFJ2 Cluster: Putative uncharacterized protein; n=1; ...    31   6.0  
UniRef50_A0Y1Z5 Cluster: Putative D-amino acid dehydrogenase, sm...    31   6.0  
UniRef50_A0LE65 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding ...    31   6.0  
UniRef50_Q9LG10 Cluster: F14J16.28; n=6; Arabidopsis thaliana|Re...    31   6.0  
UniRef50_Q95PH9 Cluster: Histidine kinase DhkG; n=2; Dictyosteli...    31   6.0  
UniRef50_Q95NP6 Cluster: Kynurenine 3-monooxygenase; n=12; Endop...    31   6.0  
UniRef50_Q4CU50 Cluster: D-isomer specific 2-hydroxyacid dehydro...    31   6.0  
UniRef50_Q23ZE9 Cluster: FAD dependent oxidoreductase family pro...    31   6.0  
UniRef50_A5AB34 Cluster: Similarity to hypothetical protein Rv16...    31   6.0  
UniRef50_A1DK69 Cluster: FAD dependent oxidoreductase, putative;...    31   6.0  
UniRef50_Q9HKG6 Cluster: Glycerol-3-phosphate dehydrogenase rela...    31   6.0  
UniRef50_Q2NEQ6 Cluster: Predicted dehydrogenase; n=1; Methanosp...    31   6.0  
UniRef50_A5ULU4 Cluster: Glutamyl-tRNA reductase, HemA; n=1; Met...    31   6.0  
UniRef50_A2BMN3 Cluster: Polysaccharide biosynthesis protein; n=...    31   6.0  
UniRef50_Q8ZMJ6 Cluster: Nitric oxide reductase FlRd-NAD(+) redu...    31   6.0  
UniRef50_P58141 Cluster: Glycerol-3-phosphate dehydrogenase [NAD...    31   6.0  
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin...    31   7.9  
UniRef50_Q8R5T2 Cluster: NADH:flavin oxidoreductases, Old Yellow...    31   7.9  
UniRef50_Q89RG4 Cluster: Blr2808 protein; n=3; Rhizobiales|Rep: ...    31   7.9  
UniRef50_Q6ARJ3 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul...    31   7.9  
UniRef50_Q5FQ43 Cluster: Glutathione reductase; n=3; Acetobacter...    31   7.9  
UniRef50_Q3JVE2 Cluster: Putative uncharacterized protein; n=3; ...    31   7.9  
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a...    31   7.9  
UniRef50_Q6HQV0 Cluster: UDP-glucose 6-dehydrogenase; n=12; Baci...    31   7.9  
UniRef50_Q1PXS7 Cluster: Putative uncharacterized protein; n=1; ...    31   7.9  
UniRef50_Q0RW49 Cluster: Short chain dehydrogenase; n=1; Rhodoco...    31   7.9  
UniRef50_Q0K351 Cluster: Transcriptional regulator; n=3; Cupriav...    31   7.9  
UniRef50_A7BCS0 Cluster: Putative uncharacterized protein; n=1; ...    31   7.9  
UniRef50_A6P064 Cluster: Putative uncharacterized protein; n=1; ...    31   7.9  
UniRef50_A5ZP59 Cluster: Putative uncharacterized protein; n=2; ...    31   7.9  
UniRef50_A4WNQ1 Cluster: Peptidase S49; n=2; Rhodobacteraceae|Re...    31   7.9  
UniRef50_A4GXI6 Cluster: D-lactate dehydrogenase; n=2; Lactobaci...    31   7.9  
UniRef50_A4FLD8 Cluster: Dihydrolipoyl dehydrogenase; n=2; Bacte...    31   7.9  
UniRef50_A3EW59 Cluster: Phosphoribosylaminoimidazole carboxylas...    31   7.9  
UniRef50_A1U0P7 Cluster: FAD dependent oxidoreductase; n=3; Mari...    31   7.9  
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro...    31   7.9  
UniRef50_A0LHH2 Cluster: FAD-dependent pyridine nucleotide-disul...    31   7.9  
UniRef50_Q22X26 Cluster: Putative uncharacterized protein; n=1; ...    31   7.9  
UniRef50_Q8TX29 Cluster: Dihydrolipoamide dehydrogenase; n=1; Me...    31   7.9  
UniRef50_Q2NF10 Cluster: Predicted UDP-N-acetylmuramoylalanine--...    31   7.9  
UniRef50_Q64C51 Cluster: Heterodisulfide reductase subunit A pol...    31   7.9  
UniRef50_Q58053 Cluster: Uncharacterized protein MJ0636; n=2; Me...    31   7.9  
UniRef50_P37061 Cluster: NADH oxidase; n=12; Bacteria|Rep: NADH ...    31   7.9  
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ...    31   7.9  
UniRef50_Q8EZB6 Cluster: Glycerol-3-phosphate dehydrogenase [NAD...    31   7.9  
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al...    31   7.9  
UniRef50_P22036 Cluster: Magnesium-transporting ATPase, P-type 1...    31   7.9  

>UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 315

 Score =  147 bits (357), Expect = 6e-35
 Identities = 70/116 (60%), Positives = 89/116 (76%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 220
           K+EKVGIVGSGLIGRSW+MLFASVGYQV L+D++ +Q++ A+   + +L+ LE  GLLRG
Sbjct: 4   KNEKVGIVGSGLIGRSWSMLFASVGYQVVLYDILPEQVSTALTATQKELQDLEAKGLLRG 63

Query: 221 NLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            L A +QF C+ GT DL   V  AIFVQEC+PE L+LKK +++ LD VV  NTILS
Sbjct: 64  KLTAAQQFACISGTNDLKELVKGAIFVQECIPERLDLKKALYKQLDAVVGPNTILS 119


>UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30;
           Coelomata|Rep: Lambda-crystallin homolog - Homo sapiens
           (Human)
          Length = 319

 Score =  129 bits (312), Expect = 2e-29
 Identities = 59/112 (52%), Positives = 86/112 (76%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V IVGSG+IGRSWAMLFAS G+QV L+D+ ++QI +A+ +I+ ++K LE+ G L+G+L+ 
Sbjct: 9   VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSV 68

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +EQ   + G  ++  AV  A+ +QECVPE+LELKKK+F  LD+++DD  ILS
Sbjct: 69  EEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILS 120


>UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to
           3-hydroxyacyl-coa dehyrogenase; n=5; Coelomata|Rep:
           PREDICTED: similar to 3-hydroxyacyl-coa dehyrogenase -
           Strongylocentrotus purpuratus
          Length = 316

 Score =  129 bits (311), Expect = 2e-29
 Identities = 60/116 (51%), Positives = 84/116 (72%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 220
           +S+K+GIVGSGLIGRSWAM+FAS G+ VT+FD+   Q+++A+  IK QL+ L + G+LRG
Sbjct: 2   ESQKIGIVGSGLIGRSWAMIFASAGFSVTIFDIEPSQVSNALKLIKSQLEELSESGMLRG 61

Query: 221 NLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            L+ + QF  +KG+  +  A+  A FVQECV E LE+K+KVF  ++  V D  ILS
Sbjct: 62  TLSVEAQFALIKGSNSMEEALAGASFVQECVFEKLEVKQKVFSEMEQYVSDGAILS 117


>UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 322

 Score =  111 bits (267), Expect = 5e-24
 Identities = 57/122 (46%), Positives = 76/122 (62%), Gaps = 2/122 (1%)
 Frame = +2

Query: 26  MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 205
           M S  +  KV ++GSGLIGR+W+ LF+S GY V L+D V  Q+ +A   I  QL+ LE  
Sbjct: 1   MTSSTEKGKVAVIGSGLIGRAWSTLFSSAGYHVALYDTVSSQLVNAKEAIISQLQELESK 60

Query: 206 GLLRGN--LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNT 379
            LL+G     A E F+ V  T DL  A+    +VQEC PENLELKKKVFQNL+  +  + 
Sbjct: 61  ELLKGRHCKTAQEAFKLVTTTDDLPQALNGVFYVQECTPENLELKKKVFQNLEATLSSSE 120

Query: 380 IL 385
           ++
Sbjct: 121 VI 122


>UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|Rep:
           LOC570274 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 327

 Score =  105 bits (253), Expect = 2e-22
 Identities = 56/119 (47%), Positives = 79/119 (66%)
 Frame = +2

Query: 32  SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 211
           S  K + + +VGSGLIGRSWAM+F S GY+V L+D    Q + AIA+I+ QL+ L++  +
Sbjct: 14  SSLKEKIITVVGSGLIGRSWAMVFLSGGYKVKLYDNKPGQASGAIAEIRKQLEELQQAKM 73

Query: 212 LRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           LRGNL+A EQ   +    DL  A+  A FVQE V E+LE K+ VF  ++ +V ++ ILS
Sbjct: 74  LRGNLSATEQLSRLSSHEDLQQALDGAFFVQESVFEDLEAKQSVFHAVEELVSESVILS 132


>UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN
           full-length enriched library, clone:A230106J09
           product:crystallin, lamda 1, full insert sequence; n=3;
           Euarchontoglires|Rep: Adult male hypothalamus cDNA,
           RIKEN full-length enriched library, clone:A230106J09
           product:crystallin, lamda 1, full insert sequence - Mus
           musculus (Mouse)
          Length = 140

 Score = 95.9 bits (228), Expect = 2e-19
 Identities = 44/85 (51%), Positives = 66/85 (77%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V IVGSGLIGRSWAMLFAS G++V L+D+ ++QITDA+ +I+ ++K+LE+ G L+G+L+A
Sbjct: 9   VVIVGSGLIGRSWAMLFASGGFKVKLYDIEQQQITDALENIRKEMKSLEQSGSLKGSLSA 68

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQE 307
           + Q   + G  +LA AV  A+ +Q+
Sbjct: 69  ERQLSLISGCGNLAEAVEGAVHIQQ 93


>UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=2; Proteobacteria|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
           Acidiphilium cryptum (strain JF-5)
          Length = 312

 Score = 83.4 bits (197), Expect = 1e-15
 Identities = 46/112 (41%), Positives = 69/112 (61%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           K+ +VG+GL+G +WA++FA  G+ V ++D VE     AI  I  +LKTLE+ GL+    +
Sbjct: 2   KIAVVGAGLVGSAWAIVFARAGHDVAVYDAVEGGADRAIGLIGDRLKTLEEVGLIE---D 58

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           A    Q V+    LA AV DA ++QE V E +E K+++F  LD VV   T++
Sbjct: 59  AAAAGQRVRVAASLADAVADAAYIQESVFETVEQKRQIFAALDAVVGPETLI 110


>UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
           Rhodobacteraceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
           - Oceanicola granulosus HTCC2516
          Length = 312

 Score = 79.8 bits (188), Expect = 2e-14
 Identities = 48/113 (42%), Positives = 63/113 (55%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KV I+G+GLIG+SWA+ FA  G  VTL D        A+A +   L  LE+  LL G   
Sbjct: 3   KVAIIGAGLIGQSWAIAFARGGCAVTLHDRDHAVADRALAVLPDALAALERMDLLGGE-T 61

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           AD     +    DLA AV  AI VQE  PE LE+K+ VF  LD+  D + +++
Sbjct: 62  ADAVGARIDAASDLADAVRGAIHVQENTPETLEVKRSVFAQLDDAADADAVIA 114


>UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5;
           Alphaproteobacteria|Rep: Mll1034 protein - Rhizobium
           loti (Mesorhizobium loti)
          Length = 315

 Score = 73.3 bits (172), Expect = 2e-12
 Identities = 44/112 (39%), Positives = 62/112 (55%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V IVGSG IGR+WA+ FA  G+ V ++D        A   I+  L  L  + LLRG  + 
Sbjct: 4   VAIVGSGFIGRAWAISFARAGHDVRMWDQSPAATGGARDYIEGVLGDLAANDLLRGQ-SV 62

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           D     +    DLA A+ DA  VQE  PENL++K++VF  +D +    TI++
Sbjct: 63  DTVLGRIATVGDLAEALADAAHVQENTPENLDVKREVFSLIDRLAGPQTIIA 114


>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
           protein; n=1; uncultured bacterium 582|Rep:
           3-hydroxyacyl-CoA dehydrogenase domain protein -
           uncultured bacterium 582
          Length = 322

 Score = 72.5 bits (170), Expect = 3e-12
 Identities = 43/112 (38%), Positives = 62/112 (55%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V +VG+GLIG  WA++FA  G+QVTL D+   ++  A   + VQL+ LE+  L       
Sbjct: 17  VSVVGAGLIGCGWAIVFARAGWQVTLQDIDLAKLQGAPKVLAVQLRMLEQHDLCADPAGI 76

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                 +    DL  AV +  +VQEC PE L LK+++F  LD +    TIL+
Sbjct: 77  ---LARISYESDLKTAVCEVDYVQECGPEVLGLKQELFSELDALTPPETILA 125


>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
           Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Geobacillus kaustophilus
          Length = 281

 Score = 70.9 bits (166), Expect = 8e-12
 Identities = 43/115 (37%), Positives = 61/115 (53%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 223
           +E + ++G+G++G   A   A VG  V L+DV E  + + +A  +  L+   K G L   
Sbjct: 2   AETIAVIGAGVMGSGIAQTAAMVGKTVYLYDVSEAALQNGLASAEKSLRRFVKTGGL-SE 60

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             A      ++ T DLA AV  A  V E VPENL LKK VFQ LD +   + IL+
Sbjct: 61  PEARAALGRIRSTVDLAEAVRGADVVIEAVPENLALKKDVFQQLDQLAKPDAILA 115


>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
           Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Geobacillus kaustophilus
          Length = 287

 Score = 70.9 bits (166), Expect = 8e-12
 Identities = 41/107 (38%), Positives = 66/107 (61%), Gaps = 3/107 (2%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           E++ +VGSG++GR  A + A  G+Q TL D+ ++Q+  A    + ++ ++ + G+ RG L
Sbjct: 3   ERLVVVGSGVMGRGIAYVGAVGGFQTTLVDIKQEQLESA----QKEIASIFEQGVARGKL 58

Query: 227 NADEQFQC---VKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLD 358
              E+ +    +  + DLA AV DA  V E VPE LELKK+VF+ +D
Sbjct: 59  TDSERQEAEARLSYSLDLAAAVRDADLVIEAVPEKLELKKQVFETID 105


>UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3;
           Sordariomycetes|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 330

 Score = 70.9 bits (166), Expect = 8e-12
 Identities = 46/118 (38%), Positives = 71/118 (60%), Gaps = 5/118 (4%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLLRG 220
           KV I+G G IG SWA LF + G +V+ FDV    E  + + +A+    L +L   GL++ 
Sbjct: 6   KVAIIGCGSIGASWAALFLAQGLEVSAFDVNPSAESFLRELVANALPVLSSL---GLVKS 62

Query: 221 N--LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +    AD +F     T D+A A+ +A FVQE  PE L+ K+K+F+ + N+VD +TI++
Sbjct: 63  SQATAADIEF-----TTDMATALKNASFVQENGPERLDFKQKLFRGVANLVDPDTIIA 115


>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
           Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Archaeoglobus fulgidus
          Length = 668

 Score = 69.3 bits (162), Expect = 2e-11
 Identities = 42/130 (32%), Positives = 74/130 (56%), Gaps = 1/130 (0%)
 Frame = +2

Query: 2   PLQTLRVV-MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK 178
           P +  +V+ M  + + + V ++G+GL+G   A + A  GY VT+ D+ ++ +   +  IK
Sbjct: 2   PRRVKQVINMDVRERIKTVAVLGAGLMGHGIAEVCAMAGYNVTMRDIKQEFVDRGMNMIK 61

Query: 179 VQLKTLEKDGLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLD 358
             L  LE+ G ++   +A+E    +K T DL  AV DA  V E VPE +E+KK+V++ +D
Sbjct: 62  ESLAKLEQKGKIK---SAEEVLSRIKPTVDLEEAVKDADLVIEAVPEVVEIKKQVWEEVD 118

Query: 359 NVVDDNTILS 388
            +   + I +
Sbjct: 119 KLAKPDCIFT 128


>UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase, NAD-binding - Pseudomonas putida W619
          Length = 320

 Score = 68.9 bits (161), Expect = 3e-11
 Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 1/126 (0%)
 Frame = +2

Query: 14  LRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT 193
           +R   +S  +   + IVG+GLIGR+WA++FA  G+ V L D+  + + ++ A I+ +L  
Sbjct: 1   MRTTASSATERGPIAIVGAGLIGRAWAIVFARAGHPVRLHDMDLQTMQNSHAYIEARLNE 60

Query: 194 LEKDGLLR-GNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVD 370
           L +  LL    L    +  CV    DLA A+ D + VQE V E +E K  +F  +D +  
Sbjct: 61  LAEFDLLNDAPLTVLARITCVP---DLADALRDVVLVQENVRETVEAKIDIFSRMDALAP 117

Query: 371 DNTILS 388
            + IL+
Sbjct: 118 KDAILA 123


>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
           Clostridium kluyveri DSM 555
          Length = 319

 Score = 68.5 bits (160), Expect = 4e-11
 Identities = 37/114 (32%), Positives = 59/114 (51%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + V ++G+G +G     L A  G  V +F   +  +      IK  LK LE+ G ++ N+
Sbjct: 4   KNVAVLGTGTMGNGIVQLCAESGLNVNMFGRTDASLERGFTSIKTSLKNLEEKGKIKTNI 63

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +  E  + +KG   +  AV    FV EC+ E+LELK++VF  LD +     IL+
Sbjct: 64  SK-EILKRIKGVKTIEEAVEGVDFVIECIAEDLELKQEVFSKLDEICAPEVILA 116


>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - Bacillus sp. SG-1
          Length = 293

 Score = 64.5 bits (150), Expect = 7e-10
 Identities = 38/113 (33%), Positives = 65/113 (57%), Gaps = 3/113 (2%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +K+ ++GSG++GR  A + A  G+Q TL DV ++Q+  A    + +L ++ + G+ RG L
Sbjct: 13  DKLVVIGSGVMGRGIAYVSAVGGFQTTLVDVEQRQLDSA----QGELTSIFQKGVDRGKL 68

Query: 227 NADEQFQC---VKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDN 376
           + +E       +  + D+A AV  A  V E VPE  E+KK VF+ +D    ++
Sbjct: 69  SKEESTDAQGRLSFSTDMAKAVESADLVIEAVPEKTEIKKAVFEKIDEYAQES 121


>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
           NAD-dependent; n=9; Clostridiales|Rep:
           Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
           Clostridium perfringens
          Length = 282

 Score = 64.1 bits (149), Expect = 9e-10
 Identities = 36/114 (31%), Positives = 59/114 (51%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           EK+ ++G+G +G      FA  GY+V + D+ ++ +   IA I   L  L   G +    
Sbjct: 2   EKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVDRGIAGINKGLTKLVSKGKITEE- 60

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           + +     + GT DL +A  D   V E   EN+E+KK++F  LD +  + TIL+
Sbjct: 61  DKEAVLSKITGTTDLGLAA-DCDLVIEAAVENMEIKKQIFAELDKICKEETILA 113


>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
           n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
           dehydrogenase - Thermoplasma acidophilum
          Length = 291

 Score = 64.1 bits (149), Expect = 9e-10
 Identities = 39/113 (34%), Positives = 65/113 (57%), Gaps = 3/113 (2%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK---VQLKTLEKDGLLRGNLN 229
           +VGSG++G+  A +FA  GY VT+ DV +  + +A+  IK     L  L K G +  +  
Sbjct: 8   VVGSGVMGQGIAQVFARSGYPVTIIDVRDDILANAVRSIKEGRYGLMNLVKKGTMTES-E 66

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            D+    ++ +     ++ DA  V E VPENL+LK+KVF +++  V +N I++
Sbjct: 67  VDKIMGKIRTSTSYG-SLSDADIVVEAVPENLDLKRKVFIDIEKNVSENAIIA 118


>UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 284

 Score = 63.3 bits (147), Expect = 2e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%)
 Frame = +2

Query: 128 LFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQE 307
           ++D+ EKQ+  A+ +++  L+ L++ GL RGNL+ADE    V  T  L   + +AI++QE
Sbjct: 1   MYDISEKQLQVALENVEKNLRKLDEHGLQRGNLSADEALLRVSTTTSLNEVMKNAIYMQE 60

Query: 308 CVPENLELKKKVFQNLDNVVDDNTILS 388
              E+L  + + ++ +D + D  TIL+
Sbjct: 61  SALEDLNFRIQFYKVIDEIADPTTILA 87


>UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=3; Bacteria|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
           Mesorhizobium sp. (strain BNC1)
          Length = 318

 Score = 62.5 bits (145), Expect = 3e-09
 Identities = 38/112 (33%), Positives = 64/112 (57%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           + IVG+G IG ++A+LFAS G  V ++D +      A  +++ +L+ L K   L  +   
Sbjct: 13  ISIVGAGSIGVAFAVLFASRGASVRIWDALPDAFDRAANELRSRLEMLAKASAL--SEPP 70

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           DE    +    +LA A+  A  VQEC PEN++LK  +F+ L ++  D+ +L+
Sbjct: 71  DEISSRISWHRNLAEALDGADLVQECAPENIDLKVDLFRWLADLTPDHVVLA 122


>UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Archaeoglobus fulgidus
          Length = 315

 Score = 62.5 bits (145), Expect = 3e-09
 Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 1/114 (0%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL- 226
           KV  +G+G +G SWA LFA  G  V ++D   + +  A A I   + TL +  +  G+  
Sbjct: 4   KVACIGAGTVGASWASLFAWRGCDVAVYDPFPEALNRAEASIARTVSTLSE--IFSGSED 61

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +       VK T +L  A+  A +VQE   E LE+K+ +F+ +D + +  TIL+
Sbjct: 62  DVKSALSRVKFTENLEEALKGAYYVQESAVEKLEVKRDLFEKMDAIAEPETILA 115


>UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1;
           Brevibacterium sp. HCU|Rep: Hydroxyacyl-CoA
           dehydrogenase - Brevibacterium sp. HCU
          Length = 316

 Score = 62.1 bits (144), Expect = 4e-09
 Identities = 37/112 (33%), Positives = 60/112 (53%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           VGI G+G IG ++A+LFA  G+ V +FD     +  +   I  ++  L++  LL    N 
Sbjct: 7   VGIFGAGSIGTAFALLFADAGFAVRIFDPDPSALERSRHVIDQRITELQRFTLLAS--NP 64

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            E  + ++       A   AI VQE  PE+++ K+ +F++L  V  D TIL+
Sbjct: 65  SEVRELIEIVSSARTAASGAILVQEAGPEDVQTKQHIFEDLTAVTSDETILA 116


>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
           Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
           Clostridium tetani
          Length = 282

 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 37/114 (32%), Positives = 60/114 (52%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +K+ ++G+G +G   A  FA+ GY+V L D+ ++ +   I  I+  L  L   G +    
Sbjct: 2   KKICVLGAGTMGAGIAQAFAAKGYEVVLRDIKDEFVERGIKGIEKGLSKLVSKGRM-AQE 60

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           + D     ++GT DL  A  D   V E   EN+E+K+++F  LD +    TILS
Sbjct: 61  DMDSILGRIEGTVDLNKAA-DCDLVVEAAIENMEIKREIFAELDRICKPETILS 113


>UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=2; Rhodobacteraceae|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Paracoccus denitrificans (strain Pd 1222)
          Length = 311

 Score = 61.7 bits (143), Expect = 5e-09
 Identities = 36/112 (32%), Positives = 58/112 (51%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           + IVG+GLIGR+WA +FA  G+ V ++D+  + +     DI   +      G  +   + 
Sbjct: 4   IAIVGAGLIGRAWAFVFARAGFDVRVWDLDPQVLERLDGDIAAMVAQTAPFG--QAGADP 61

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           D     ++   DLA A+  A  VQE  PE L +K+++F  LD +     IL+
Sbjct: 62  DATAARIRAVPDLAGALDGAELVQESGPEVLAIKRELFARLDGLAAAGVILA 113


>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Archaeoglobus fulgidus
          Length = 661

 Score = 61.3 bits (142), Expect = 6e-09
 Identities = 35/112 (31%), Positives = 61/112 (54%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V ++G+G +G + A + A  G+ V L DV E Q+  A+  I+  L+   + G +  + + 
Sbjct: 9   VAVIGAGSMGHAIAEVVAIHGFNVKLMDVSEDQLKRAMEKIEEGLRKSYERGYI--SEDP 66

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           ++  + ++ T DL     DA  V E +PE  +LKKKVF  ++    D+TI +
Sbjct: 67  EKVLKRIEATADLIEVAKDADLVIEAIPEIFDLKKKVFSEIEQYCPDHTIFA 118


>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
           n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
           dehydrogenase, putative - Treponema denticola
          Length = 309

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 36/121 (29%), Positives = 62/121 (51%)
 Frame = +2

Query: 26  MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 205
           M  K K  KV +VG G +G   + +FA  G+ V +  + +  +  A+  IK+ L     +
Sbjct: 1   MIEKGKKIKVAVVGDGTMGHGISEVFAKAGHTVQIIGLNDASLKSALDRIKLSLNEFVAE 60

Query: 206 GLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           GL+  + + D     +  + D+  A  DA  V E +PEN++LK + F  L+ +   +TIL
Sbjct: 61  GLVSAS-DIDTIVGRISFSTDIQKA-EDAAIVIEALPENMDLKTETFGKLEKICPQDTIL 118

Query: 386 S 388
           +
Sbjct: 119 A 119


>UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
           Alphaproteobacteria|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - Roseovarius sp. HTCC2601
          Length = 316

 Score = 60.1 bits (139), Expect = 1e-08
 Identities = 35/113 (30%), Positives = 59/113 (52%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           K+ I+GSG+IG SWA+++A  G  V +++  E     A+  ++  L +     LLR    
Sbjct: 5   KIAILGSGVIGASWAIVYARSGCDVAIYERSEAFRDSAMQRLESSLAS--SASLLRDGET 62

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             +    +     L  AV  A FV EC+ ENL+ K+++F  L++  +   IL+
Sbjct: 63  VQDVLARITLHDTLEAAVAGADFVHECIVENLDSKRQIFAALNDAAEPEAILA 115


>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
           Bifidobacterium longum|Rep: Possible butyryl-CoA
           dehydrogenase - Bifidobacterium longum
          Length = 319

 Score = 59.7 bits (138), Expect = 2e-08
 Identities = 35/109 (32%), Positives = 53/109 (48%)
 Frame = +2

Query: 62  VGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADEQ 241
           VG+G +G +  + FA  GY V L    E  +  A+  I+   +   + GLL+     D  
Sbjct: 14  VGTGTMGHAITLQFALAGYPVHLVGRSEASLEKAMKAIRSDAEDFAEAGLLKAGDTVDTV 73

Query: 242 FQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
              + G  D A  V D  FV E V ENL++KK V+  +++    + ILS
Sbjct: 74  LARITGYADYASGVADVDFVIESVAENLDVKKSVWTEVEHAAPKDAILS 122


>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
           multifunctional protein MFP-a; n=3;
           Magnetospirillum|Rep: Glyoxysomal fatty acid
           beta-oxidation multifunctional protein MFP-a -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 703

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 40/115 (34%), Positives = 63/115 (54%), Gaps = 3/115 (2%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KVGI+G+G +G   AM FA++G  VT+ DV ++ +   +  I+   K  E+  + RG+L 
Sbjct: 296 KVGIIGAGTMGGGIAMCFANIGIPVTIIDVSDENLQRGLGVIR---KNYER-SVSRGSLT 351

Query: 230 ADE---QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
            ++   +   +  + D A A+ DA    E V E +ELKK +F  LD V+    IL
Sbjct: 352 QEQLESRMGLLSASTDYA-ALKDADLAIEAVFEKMELKKDIFAKLDAVLPAGAIL 405


>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
           cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
           - Halobacterium salinarium (Halobacterium halobium)
          Length = 286

 Score = 59.3 bits (137), Expect = 3e-08
 Identities = 35/122 (28%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
 Frame = +2

Query: 26  MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEK 202
           M S   +E +G+VG+G +G   A + A+ GY V + D+ ++ +      I+  L + +  
Sbjct: 1   MRSLADTETIGVVGAGTMGAGIAQVAATAGYTVVMRDIEQEYVDAGFDSIESSLDRFVSN 60

Query: 203 DGLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 382
           D L     +AD     + GT DLA  + D   V E   E++E+K+ +F++LD+ + ++ +
Sbjct: 61  DDL--SEADADAIVDRITGTTDLA-ELADCDVVIEAAVEDMEIKQDIFRDLDDALPEDVV 117

Query: 383 LS 388
           L+
Sbjct: 118 LA 119


>UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Planctomyces maris DSM 8797|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Planctomyces maris DSM 8797
          Length = 311

 Score = 58.8 bits (136), Expect = 3e-08
 Identities = 38/116 (32%), Positives = 62/116 (53%), Gaps = 3/116 (2%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ-LKTLEKDGLL--R 217
           +++GI+G+GLIG SWA  FA+ G +V +FD V   +     ++ VQ L+ L    L+  +
Sbjct: 2   QEIGILGAGLIGASWATFFAAQGLRVRIFD-VNNTVKQQAQELSVQNLQRLADLELISRK 60

Query: 218 GNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
               A+E+   V    +L   + D  +VQE V E+ E+K  V+Q  +    +  IL
Sbjct: 61  DAATAEEKLNVVDSLAEL---LTDVEYVQESVIEDYEIKADVYQQFEQYAPEAAIL 113


>UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
           n=3; Bordetella|Rep: Putative 3-hydroxyacyl-CoA
           dehydrogenase - Bordetella bronchiseptica (Alcaligenes
           bronchisepticus)
          Length = 313

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 40/114 (35%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK-TLEKDGLLRGNLN 229
           V ++G G+IG SWA++FA  G +VT   +VE+     +A +  +L   +E+   L G   
Sbjct: 4   VAVIGGGIIGASWAVVFARRGLEVT---IVERDAA-CLAGLPARLAGMIERSASLLGAGE 59

Query: 230 ADEQFQCVKGTCD-LAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                    G  D LA AV  A +VQE V ENL LK+ +F  LD +   + +L+
Sbjct: 60  QPGDVAARIGATDALAAAVGRADYVQEAVSENLALKRTLFAELDALAPAHALLA 113


>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
           Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Thermoplasma volcanium
          Length = 659

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 37/113 (32%), Positives = 57/113 (50%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KV ++GSG++G   A   A  GY V L D+ +  +  A A+I   L  L K G L    +
Sbjct: 5   KVTVIGSGIMGHGIAETIALAGYDVNLEDISDDVLAKAKAEIDASLDRLVKSGKLS---D 61

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             +    +     +  +V DA  V E VPE L++K++VF  LD    ++ IL+
Sbjct: 62  KTKVLGRIHYFTSIPESVKDADLVIEAVPEILDIKRQVFAQLDQSTKEDAILA 114


>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
           Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 518

 Score = 58.0 bits (134), Expect = 6e-08
 Identities = 35/112 (31%), Positives = 59/112 (52%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           VG++G+G +G   A + A+ G+ V L+D+ E     A+A I+ Q   L + G L     A
Sbjct: 20  VGVIGAGAMGAGIAQVAAAAGHTVLLYDLNEAACDKALAGIRAQFARLAEKGRLE-PAQA 78

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           D     ++   +LA     A+ V E   E L++K+++F  L+  VDD  +L+
Sbjct: 79  DAAGARIRAVRELADFAGAALIV-EAAAERLDVKREIFATLERHVDDACLLA 129


>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
           Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Dokdonia donghaensis MED134
          Length = 394

 Score = 57.2 bits (132), Expect = 1e-07
 Identities = 37/114 (32%), Positives = 58/114 (50%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + +GI+G+G +G   A + A+ G  V LFDV ++ +  A   ++  LK L + G +  + 
Sbjct: 3   KNIGIIGAGTMGSGIAQVAATAGCAVKLFDVNQEALDKAKEALEKVLKRLIEKGRIDASE 62

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               Q      T    +A  D     E + ENLE+KKKVFQ L+  V D  I++
Sbjct: 63  KDRIQANITYVTTLKELANADLTI--EAIVENLEVKKKVFQELETYVSDTAIIA 114


>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep:
           3-hydroxybutyryl-CoA dehydrogenase - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 387

 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 32/114 (28%), Positives = 56/114 (49%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +K+ ++GSG +G   A +    GY V + DV ++ + + +  +K  +  L   G L    
Sbjct: 7   KKIAVIGSGAMGHGIAQVCIMAGYTVVMVDVKQEFLDNGMKKVKESMDFLVGKGKLSAE- 65

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           + D     +  + D   AV D   V E VPE ++LKKKVF ++ +      +L+
Sbjct: 66  DKDRMMGQLSTSLDNKAAVADVQVVIEAVPEIMDLKKKVFADVSSAAPAEALLA 119


>UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 589

 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 37/118 (31%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
 Frame = +2

Query: 38  FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT-LEKDGLL 214
           ++   V I+G+G++GR  A ++AS GY V + D   +Q  D +A +K  +    E  G  
Sbjct: 11  YRERPVAILGAGVLGRRIACIWASAGYDVQVRDPSPEQRADCVAYVKQHVVAYAEHTGAA 70

Query: 215 RGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            G +   E         DL   V +A  V E VPE ++LK   F+ LD +   + IL+
Sbjct: 71  PGEVTTSE---------DLKNTVNNAWLVIEAVPEKIQLKIDTFEQLDKLAPTDCILA 119


>UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome.
           precursor; n=6; Pezizomycotina|Rep: Contig An11c0270,
           complete genome. precursor - Aspergillus niger
          Length = 599

 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 38/115 (33%), Positives = 58/115 (50%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 223
           S  + ++G+G++GR  A +FA+ GY V L+D        A+  +   LKT  K    +GN
Sbjct: 12  SRPLALLGAGVLGRRIACVFAAAGYNVNLYDPSLSAQQAALDYVTQNLKTYSK--FSKGN 69

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                +F   +   DL   V DA  V E VPE+L++K  V   LD +   + IL+
Sbjct: 70  ----RRFGHCRAFSDLESTVSDAWLVIEAVPEHLQMKIDVMGELDKLAPVDCILA 120


>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
           Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
           - Haloarcula marismortui (Halobacterium marismortui)
          Length = 654

 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 35/112 (31%), Positives = 58/112 (51%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V ++G+G +G   A + A  GY V L D+    + D   +I+  L+ L + G L  + + 
Sbjct: 11  VAVLGAGTMGHGIAEVAAIAGYDVVLRDIDAAIVEDGYDEIEWSLEKLAEKGRL--DEDP 68

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           D+    V  T DL  AV DA  V E  PE L +K+ +F+++D     + +L+
Sbjct: 69  DDVAARVATTTDLEAAVSDADLVIEAGPEQLSVKQDIFESVDAAAPADALLA 120


>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
           cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
           - Archaeoglobus fulgidus
          Length = 295

 Score = 56.0 bits (129), Expect = 2e-07
 Identities = 36/114 (31%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           +G+VG+G++G   A + A  GY V + DV E+ +  A+  I+     L +  + +G ++ 
Sbjct: 9   IGVVGAGVMGHGIAQVAARTGYDVVMVDVSEEVLKKAMELIESGPFGLRRL-VEKGKMSE 67

Query: 233 DEQFQCVKG--TCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           DE    +    T     A+ DA F+ E V E  +LKKK+F  LD +    TI++
Sbjct: 68  DEAKAVMARIRTSTSLEALKDADFIIEAVTEKADLKKKIFAELDRICKPETIIA 121


>UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4;
           Sulfolobaceae|Rep: 3-hydroxyacyl-CoA-dehydrogenase -
           Sulfolobus solfataricus
          Length = 324

 Score = 55.6 bits (128), Expect = 3e-07
 Identities = 30/113 (26%), Positives = 58/113 (51%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KV ++G+G+IG  W  L  + GY+V L+   ++ +  A+A +   L  L+  G++  N  
Sbjct: 10  KVAVIGAGVIGVGWTTLLLAKGYKVNLYTEKKETLEKALAKVSAYLVNLKNLGMI--NEE 67

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            +     + G   +  A+ +  FV E + E+   KK +F+ LD  +  + I++
Sbjct: 68  PESYITNLTGITKIDDAIHNVDFVIEAIIEDYTAKKNLFKLLDTQLPQDIIIA 120


>UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Burkholderia sp. 383|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Burkholderia sp. (strain 383)
           (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
           R18194))
          Length = 333

 Score = 55.2 bits (127), Expect = 4e-07
 Identities = 36/113 (31%), Positives = 58/113 (51%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           E VGI+G+G IG SWA LF + G +V ++D   +        ++    +LE+ GL R   
Sbjct: 12  EVVGILGAGTIGASWAALFLAAGLEVDVYDPSPEGEAFVRDYVRHAWPSLERLGLARRGD 71

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
               +F           AV  A FVQE VPE +E+K  +++ +++ +D   I+
Sbjct: 72  PGRLRFVATPEE-----AVARAQFVQESVPERIEIKHALYRRIEDHLDPRAIV 119


>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
           Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Bacillus sp. NRRL B-14911
          Length = 295

 Score = 55.2 bits (127), Expect = 4e-07
 Identities = 34/114 (29%), Positives = 57/114 (50%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + + +VG+G +G   AML A  G++ TL D+ EK +  A   ++  +      G L    
Sbjct: 8   KNITVVGAGQMGHQIAMLCALGGFETTLHDMQEKALDQAQEKLRGIMDKWAAKGKLPSE- 66

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             +  F  ++ T D   AV  A F+ E V E LE+K++VF  L+ +   + I +
Sbjct: 67  QIEAAFSRLRCTSDFGEAVKSADFIIEAVVEKLEVKREVFSMLEEMAPPHAIFA 120


>UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA
           dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
           COG1250: 3-hydroxyacyl-CoA dehydrogenase -
           Brevibacterium linens BL2
          Length = 311

 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 39/114 (34%), Positives = 64/114 (56%), Gaps = 1/114 (0%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK-TLEKDGLLRGNL 226
           KV I+G+G+IG +WA  F + G+ VT FD  +     A A ++ Q++  LE  G   G++
Sbjct: 6   KVAILGTGVIGAAWATGFLTAGHTVTAFDPAD----GAEARLRSQVEGNLEVTG--EGDI 59

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            +  +     G+  LA +V DA FVQE  PE L++K+ +    D+ V  + I++
Sbjct: 60  TSAMERLHFAGS--LAESVGDADFVQENGPERLDIKQSMLAETDSAVPASAIIA 111


>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Symbiobacterium thermophilum
          Length = 517

 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 34/116 (29%), Positives = 61/116 (52%), Gaps = 3/116 (2%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           ++G+VG+G +G   A + A  G+ V L+DV  + +  A+  ++  L+     G +     
Sbjct: 3   RLGVVGAGTMGAGIAQVAAQSGFDVLLYDVDPEALARALGRVESDLQRQAARGRI----- 57

Query: 230 ADEQFQCVKGTCDLAIAVXD---AIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            D Q   V G      ++ D   A FV E  PE+LELK+++F+ LD +  ++ +L+
Sbjct: 58  PDAQVAEVLGRITTTTSLGDFAAADFVIEAAPEDLELKRRLFERLDRLCREDVVLA 113


>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
           Desulfitobacterium hafniense Y51|Rep: Putative
           uncharacterized protein - Desulfitobacterium hafniense
           (strain Y51)
          Length = 313

 Score = 54.4 bits (125), Expect = 7e-07
 Identities = 35/116 (30%), Positives = 59/116 (50%)
 Frame = +2

Query: 38  FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLR 217
           F++ K+ +VG+G++G   A L+A  G+QV L+D   +Q+  A   I   ++ L K+GL  
Sbjct: 2   FENWKLLVVGAGVMGSGIAQLYACKGFQVALYDKFPEQLDRAKQLIANNMENLIKEGLAT 61

Query: 218 GNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
               A+     +    +L      A  V E V EN ++K++ F  LD +   + IL
Sbjct: 62  QE-EAERTKTLISYETELEKCAPQADLVLESVFENADVKRETFAQLDKLCASDCIL 116


>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
           Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Sulfolobus solfataricus
          Length = 384

 Score = 54.4 bits (125), Expect = 7e-07
 Identities = 33/114 (28%), Positives = 61/114 (53%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +K+G+VG+G +G   A + A   Y V++ D+    +  A   I   L    + G ++   
Sbjct: 4   KKIGVVGAGTMGHGIAEVSALANYNVSVVDISWDFLNRAKERIMESLNKFYEKGQIKEK- 62

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             ++  + ++ +    + + DA FV E VPE +ELK+KVF+ LD++   +T L+
Sbjct: 63  -PEDIMKRIEFSTSYDV-MRDADFVIEAVPEIIELKRKVFETLDSITPSHTFLA 114


>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
           cellular organisms|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 282

 Score = 54.0 bits (124), Expect = 1e-06
 Identities = 37/116 (31%), Positives = 61/116 (52%), Gaps = 3/116 (2%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK---TLEKDGLLRG 220
           KVG++G+G +G   A +FA  GY+V L DV  + +   +A IK  L+      K    +G
Sbjct: 5   KVGVIGAGTMGNGIAHVFAKSGYKVVLCDVKREFLDRGLATIKKNLEREVAKNKISQEQG 64

Query: 221 NLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            + AD  +  ++   DLA    D   V E   E  E+K ++F++LD++   + IL+
Sbjct: 65  QVAADHIYPTLERK-DLA----DCDIVVEAASERFEIKAELFRDLDSICRPDVILA 115


>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
           Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
           - Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
          Length = 301

 Score = 54.0 bits (124), Expect = 1e-06
 Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 1/113 (0%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           VG+VGSGL+G   A + A  GY V L D+ E  +  A+  I   L  L + G L     +
Sbjct: 10  VGVVGSGLMGSGIAQVAAVAGYAVRLHDIEESALHRALTTIDESLHRLARKGKLS---TS 66

Query: 233 DEQFQCVKGTCDLAIA-VXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           D +    + T    +A + D+  V E V E L++K+ VF  L  +V  N +L+
Sbjct: 67  DVEAAKARITTTRRLADLADSDVVVEAVYEELDVKRVVFAELAAIVRPNVLLA 119


>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
           n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
           putative - Deinococcus radiodurans
          Length = 347

 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 34/119 (28%), Positives = 55/119 (46%)
 Frame = +2

Query: 32  SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 211
           S    + V + GSG++G   A   A  G+ V L+D+ +  I  A   +       ++D  
Sbjct: 50  SSMSIKTVTVCGSGVLGSQIAFQTAFHGFDVHLYDINDAAIAKARETLGKLQARYQQDLK 109

Query: 212 LRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +      D  F  +    D+A AV     V E +PEN+++K+K +  L  V D NTI +
Sbjct: 110 VDAQQTGDA-FARISFFTDIAEAVKGVDLVIEAIPENMDIKRKFYNQLGEVADPNTIFA 167


>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep:
           3-hydroxybutyryl-CoA dehydrogenase - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 289

 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 37/114 (32%), Positives = 58/114 (50%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           ++V I G+G +GRS  +  A  G +V L+DV E  +  A   + V++  +   G L    
Sbjct: 7   KRVLIAGAGTMGRSIGLSCAVRGCEVILYDVKEDALEAARRAMAVKIDKMVPAGALTPEA 66

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            A+     +  T DLA A  DA  V E VPE+ ++K + F+ L  V  + TI +
Sbjct: 67  -AESIKANITTTTDLAAAGADADLVSESVPEDPDIKGEFFEKLHGVCPERTIFT 119


>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
           Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Sulfolobus acidocaldarius
          Length = 657

 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 34/113 (30%), Positives = 56/113 (49%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           +VG+VG+G +G   A + A  G+ V L DV E  + +A+  I+  L+ L +   ++ N N
Sbjct: 6   RVGVVGAGTMGHGIAEVVAIAGFNVVLTDVNEDILRNALEKIRWSLEKLREKRQIKENPN 65

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                  +K T        D  F+ E   E  ++K+K+F  LD VV  + I +
Sbjct: 66  T--VLSRIKTTVSFG-DFSDVDFIIEAAIERSDVKRKIFSELDRVVKKDAIFA 115


>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
           precursor; n=1; Psychromonas ingrahamii 37|Rep:
           3-hydroxybutyryl-CoA dehydrogenase precursor -
           Psychromonas ingrahamii (strain 37)
          Length = 511

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 33/118 (27%), Positives = 62/118 (52%)
 Frame = +2

Query: 35  KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLL 214
           K   + V ++G+G +G   A + A  GYQV LFD+ + +  +A  +I+ QL+   K G +
Sbjct: 3   KLLFKTVAVIGAGAMGAGIAQVAAQSGYQVYLFDLAKGKAEEAKENIEKQLERRVKKGRM 62

Query: 215 RGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                 +     +  + +L+  +  A  V E + ENLE+K+ +F+ L+ +   + IL+
Sbjct: 63  E-QQTLESTLLRIHCSSELS-EIASANLVIEAIVENLEIKQGLFKELETICSADCILA 118


>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
           n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
           dehydrogenase - Streptomyces coelicolor
          Length = 504

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 35/116 (30%), Positives = 61/116 (52%), Gaps = 1/116 (0%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRG 220
           S  V +VG+G +G+  A +    G+ V L+D V+ +  +A   I  +L + +EKD L   
Sbjct: 7   SSPVAVVGTGTMGQGIAQVALVAGHPVRLYDAVDGRAREAADAIGARLDRLVEKDRLTGA 66

Query: 221 NLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             +A        GT      + D   V E V E L++K+++F+ L++VV D+ +L+
Sbjct: 67  ERDAARARLVPAGTLG---ELADCALVVEAVVERLDVKQELFRALEDVVGDDCLLA 119


>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - unidentified eubacterium SCB49
          Length = 403

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 2/114 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGLL-RGNL 226
           +GI+G+G +G   A + A+ G  V LFD+ +  +  A A + K+  + +EK  +      
Sbjct: 20  IGIIGAGTMGSGIAQVAATAGCTVKLFDLNQAALDKAKASLEKIMTRLVEKGRVTEEEKA 79

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
              E    V    +LA    D+    E + E+L +KKKVFQ L++ V D+ I++
Sbjct: 80  RIQENISYVNALKELA----DSDLTIEAIIEDLGIKKKVFQELESYVSDSCIIA 129


>UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
           n=1; Marinomonas sp. MED121|Rep: Putative
           3-hydroxyacyl-CoA dehydrogenase - Marinomonas sp. MED121
          Length = 323

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 32/112 (28%), Positives = 58/112 (51%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KVG++G+G+IG +WA+ +  +G +V  +D         +  +     T+EK GL  G   
Sbjct: 12  KVGVIGTGVIGGAWALHYLRMGMEVVAYDPGPNSKEKLLTMVDNIWPTIEKLGLREG--A 69

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           + ++ + V     LA  V     +QE  PE L+ K+ +F +LD +V  + ++
Sbjct: 70  SKDKLRFVDSLDALANQVE---VIQESTPERLDAKRSLFADLDCIVPADVVI 118


>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
           Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 669

 Score = 52.8 bits (121), Expect = 2e-06
 Identities = 33/115 (28%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTL-EKDGLLRGN 223
           + + ++G+G +G     + A  GY V + D+ ++ + D   +I+  L  L E+D L +  
Sbjct: 22  DTIAVLGAGNMGHGITEVAALAGYDVRMRDIKDEFVEDGYDNIEWSLNKLAERDQLTQEE 81

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             AD     V    D+  AV D   V E VPE +E+KK V+  ++    +N I +
Sbjct: 82  --ADAALDRVTPLVDVEEAVSDVDVVIEAVPEKMEIKKDVYTEVEEHAPENAIFA 134


>UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
           protein; n=16; Alphaproteobacteria|Rep:
           3-hydroxyacyl-CoA dehydrogenase family protein -
           Silicibacter pomeroyi
          Length = 487

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 4/113 (3%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLL-RGNL 226
           I+G G+IG  WA  F   G+ V +FD     E++I + +A+ +  L  L    L   G L
Sbjct: 6   IIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGEVLANARRSLPGLSDMPLPPEGKL 65

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           +            DL  AV  A ++QE VPE L+LK KV++++    D   IL
Sbjct: 66  SFH---------ADLGEAVTGAAWIQESVPERLDLKLKVYRSIQEACDPGAIL 109


>UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
           precursor; n=2; Psychrobacter|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase precursor - Psychrobacter cryohalolentis
           (strain K5)
          Length = 533

 Score = 52.0 bits (119), Expect = 4e-06
 Identities = 36/118 (30%), Positives = 59/118 (50%), Gaps = 4/118 (3%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + + I+G+G++G   A + A VG QV LFD            ++  L+ L   G      
Sbjct: 4   KSLAIIGTGIMGMGIAQIAAQVGIQVLLFDAKAGAAEQGRQSLQAMLEKLAAKGKF---- 59

Query: 227 NADEQFQCVKGTC----DLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             DEQ Q          D+A  + +A  V E + ENLE+K+++F+ L+++V   TIL+
Sbjct: 60  -TDEQLQSTLKNLIVIEDIA-KIAEADVVIEAIIENLEIKQQLFKQLESIVPAETILA 115


>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
           root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Thermobifida fusca (strain YX)
          Length = 398

 Score = 51.6 bits (118), Expect = 5e-06
 Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KVG+VG G +G     +FA  G+ VT  ++ +  +      ++   K+L K  + +G L 
Sbjct: 7   KVGVVGLGTMGAGIVEVFARAGFTVTGVEIDDAALERGRTHLE---KSLAK-AVAKGKLT 62

Query: 230 ADEQFQCVKGTCDLAIA---VXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            DEQ + + G      +   + DA    E VPE L++K+ VF +LD ++    IL+
Sbjct: 63  EDEQ-RAILGRVTFTTSRDDLADAHLAVEAVPERLDIKRSVFADLDRILPPAAILA 117


>UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;
           n=3; Rhodobacteraceae|Rep: Putative hydroxlacyl-CoA
           dehydrogenase - Sulfitobacter sp. NAS-14.1
          Length = 309

 Score = 51.6 bits (118), Expect = 5e-06
 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 3/115 (2%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLLRGN 223
           V ++G GLIG SWA LF   G+ V  +D            +A    QL+ +      +G 
Sbjct: 7   VAVIGCGLIGASWAALFQHAGHTVRAWDPDTGARDGFAARVAGPLAQLQEISAGAAPQGA 66

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           L+  E  Q          A+ D + +QE  PEN+ LK +++  ++++V  + I++
Sbjct: 67  LSTHESLQ---------DALQDVVLIQENAPENVPLKHQLYAQIESIVAPDVIIA 112


>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=1; Halorubrum lacusprofundi ATCC
           49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
           - Halorubrum lacusprofundi ATCC 49239
          Length = 676

 Score = 51.6 bits (118), Expect = 5e-06
 Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 223
           ++V ++G+G +G   A + A  GY V L D+ E+ +      I+  L K  EKD +  G 
Sbjct: 20  QRVTVLGAGNMGHGIAEVAALAGYDVALRDIEEEFVQGGYDQIEWSLGKLAEKDRI--GE 77

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNL 355
             AD     V+   DL  ++ DA  V E VPE + +KK V+  +
Sbjct: 78  DEADAALDRVEAFVDLEDSLADADVVVEVVPEKMAIKKDVYDEV 121


>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
           dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
           3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
           (strain K12)
          Length = 475

 Score = 51.6 bits (118), Expect = 5e-06
 Identities = 35/114 (30%), Positives = 55/114 (48%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + V ++GSG +G   A + AS G+QV L+D+  + +T AI  I  +L +    G L    
Sbjct: 6   QTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAET 65

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                 + +  T   A+A  D +   E   E LE+KK +F  L  V    T+L+
Sbjct: 66  CERTLKRLIPVTDIHALAAADLVI--EAASERLEVKKALFAQLAEVCPPQTLLT 117


>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
           Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Bacillus halodurans
          Length = 287

 Score = 51.2 bits (117), Expect = 7e-06
 Identities = 38/116 (32%), Positives = 62/116 (53%), Gaps = 4/116 (3%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ-LKTLEKDGLLRGNLN 229
           VG+VG+G +G   A L A  G QV L D+ + Q+     DI  Q + T  +  + +G ++
Sbjct: 6   VGVVGAGTMGSGIANLAAMSGLQVVLLDLDDNQL-----DIAWQKINTFMEKSVAKGKMS 60

Query: 230 ADEQFQC---VKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             E+      +K T      + +A  V E V ENL++KK+VF  LD  + ++TI++
Sbjct: 61  EAEKEAALGRIKSTTTYE-ELAEADLVIEAVIENLDVKKEVFHTLDTCLANDTIIA 115


>UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=1; Ignicoccus hospitalis KIN4/I|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Ignicoccus hospitalis KIN4/I
          Length = 683

 Score = 50.8 bits (116), Expect = 9e-06
 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KV +VG+G++G   A + A  G  V + D+ ++ +  A+  IK  L+ L   G L+    
Sbjct: 25  KVLVVGAGVMGHGIAQVAAMSGLNVRMIDIKQEFLDRAMERIKESLEKLYAKGKLKEPPE 84

Query: 230 AD-EQFQCVKGTCD----LAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
              ++ + +    D     A A  D  FV E VPE LELK+ VF  LD     + IL+
Sbjct: 85  EVLKRIETMVANPDDESSYAEAAKDVDFVIEAVPEKLELKRAVFSVLDKYAPPHAILA 142


>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
           Mesorhizobium sp. (strain BNC1)
          Length = 485

 Score = 50.8 bits (116), Expect = 9e-06
 Identities = 33/115 (28%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           +G++G+G +G   A + A+ G++V LFDV        +     +L TL K G +     A
Sbjct: 11  IGVIGAGTMGAGIAQVAAAAGHKVLLFDVASGAAASGLERTAKELATLVKRGKME-QKRA 69

Query: 233 DEQFQCVKGTCDLAIAVXD---AIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +E    + G   +A  + D   A    E + E L++K+KVF  L+ ++ ++ IL+
Sbjct: 70  EE----IIGRITIAEKLEDLAPAALTVEAIVERLDVKQKVFAQLEAILAEDAILA 120


>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - Rhodococcus sp. (strain RHA1)
          Length = 286

 Score = 50.8 bits (116), Expect = 9e-06
 Identities = 35/112 (31%), Positives = 57/112 (50%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           VG+VG+G +G   A   A  G+ V + D   + +  A + ++  L+     G   G   A
Sbjct: 9   VGVVGAGTMGAGVAECLAQAGHDVIVVDPDPQAVDQARSRMRDSLRLAILLGRAGGPKPA 68

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +   + V  T ++   + DA  V ECVPE ++LK+KVF  LD V   + +L+
Sbjct: 69  EVTAR-VHWTGEMT-DLRDAAVVIECVPERIDLKEKVFAELDRVCAPDALLA 118


>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
           Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Bordetella parapertussis
          Length = 354

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 36/114 (31%), Positives = 52/114 (45%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + + +VG+G +G   A LFAS G+ V L D +   +T A   I+ QL     D +     
Sbjct: 50  QNLAVVGAGAMGSGIAALFASKGFDVVLIDPMAGALTRAAQVIERQLGVYAPDAIA---- 105

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                 Q ++    L  A   A  V E VPE L LK+ +F  LD + D   I +
Sbjct: 106 ---PAMQRIRMDAGLE-AACSAQLVIEAVPEKLALKRDIFARLDTLCDPQAIFA 155


>UniRef50_O69856 Cluster: Fatty acid oxidation complex
           alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
           acid oxidation complex alpha-subunit - Streptomyces
           coelicolor
          Length = 709

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 34/114 (29%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLF-ASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           KVG+VG+GL+    A+LF   +   V L D+ ++++   +  +  ++  L   G +  + 
Sbjct: 340 KVGVVGAGLMASQLALLFLRRLEVPVVLTDIDQERVDKGVGYVHAEIDKLLGKGRVNQD- 398

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            A+     V G  D A    DA FV E V E + +K+KVF  ++ V   + IL+
Sbjct: 399 KANRLKALVTGVLDKAEGFADADFVIEAVFEEMGVKQKVFAEVEAVAPAHAILA 452


>UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase
           NAD-binding; n=3; Alphaproteobacteria|Rep:
           3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
           sp. (strain CCS1)
          Length = 687

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           K+ IVG G +G   A    SVG  V L +       DAIA  +  + TL   GL RG L+
Sbjct: 284 KIAIVGGGTMGAGIAYACLSVGLPVVLLET----DADAIARAQHNIDTLIGAGLKRGRLD 339

Query: 230 ADEQFQCVKGTCDLA---IAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            D     ++    L     A  DA  V E   E++++KK +F  LD  V  +T+L+
Sbjct: 340 -DSGAAALRDRLTLTEDYAAASDATLVIEAAFESMDVKKDIFAKLDAAVSPDTVLA 394


>UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9;
           Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 317

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 35/104 (33%), Positives = 49/104 (47%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           ++V ++G+G+IG SWA LF + G  V   DV           +      LE+ GL     
Sbjct: 6   KRVAVIGTGVIGASWAALFLAKGLDVAATDVAPDAEARLRQYLDAAWPALEELGLAPAAS 65

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLD 358
            A   F     T DLA AV  A  VQE  PE ++ K+ ++  LD
Sbjct: 66  RARLTF-----THDLAEAVAGAGLVQENGPERIDFKRTLYGQLD 104


>UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=3; Actinomycetales|Rep: 3-hydroxyacyl-CoA
           dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
          Length = 323

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 4/116 (3%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGL-LR 217
           +V ++G+G IG  W  LF + GY+V +      +E  I DA+      L    +D   L 
Sbjct: 11  RVAVIGAGSIGLGWITLFLAHGYRVRVNSTRSNIETVIHDALRLFTPGLPGASRDPADLA 70

Query: 218 GNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           G L  +          DL  AV D   VQE  PENLE+K+ +F  L+      T+L
Sbjct: 71  GRLEIEP---------DLERAVADVAVVQENTPENLEIKQDLFARLEKHAAAGTLL 117


>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
           Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
           - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 287

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 1/111 (0%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGNLNAD 235
           +VG+G +G   AM+ A  G+QV L DV    +  A  +++ ++ + +EK      ++ A 
Sbjct: 6   VVGAGAMGSQIAMVCALAGHQVCLHDVDPAMLERADRELRDRMARQVEKGRRTADDVTAA 65

Query: 236 EQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            +   V  +   A A  DA  V E V E +E+K ++F  LD +    TIL+
Sbjct: 66  FERLRVADSLAAAAAAADADLVIEAVVERIEVKSELFAELDRLCPPATILA 116


>UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=2; Proteobacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase, NAD-binding - Comamonas testosteroni KF-1
          Length = 706

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 37/116 (31%), Positives = 61/116 (52%), Gaps = 3/116 (2%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           +VGI+G+G +G   AM FA+ G  V L +  +  +   +A I+   +      + RG L 
Sbjct: 307 RVGILGAGTMGGGIAMAFANAGIPVVLCEREQAALDRGMAMIERNYQI----SVSRGGLT 362

Query: 230 AD---EQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           A+   E+ Q ++ T DL+ A  +   V E V E++ +K+ VF  LD +    TIL+
Sbjct: 363 AEAVKERMQHIQQTLDLS-AFAEVDLVIEAVFEDMAIKRDVFVQLDRICRKGTILA 417


>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
           cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
           - Haloarcula marismortui (Halobacterium marismortui)
          Length = 295

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 3/115 (2%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN- 229
           V I+G+G +G   A + A  G+ V+L D+    + D +  I+  L+    +G+ R  +  
Sbjct: 4   VAILGAGTMGHGIAQVSAMAGHDVSLRDIEADIVDDGLTAIESNLE----EGIAREKVTE 59

Query: 230 --ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             A+     +KGT  L  AV  A  V E VPE + +K +    +++ VD  T+++
Sbjct: 60  STAEATIDRLKGTTSLEEAVTGADLVVEAVPEEMAIKHETLTAVESHVDPATLIA 114


>UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Archaeoglobus fulgidus
          Length = 304

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           EK+G+VG GL+G      FA  G +V   DV E+++   +  IK     L++  + +G +
Sbjct: 3   EKIGVVGFGLMGTQITQFFAQQGLEVVAIDVSEERLRKGMEAIKAGRFGLQR-LVEKGKI 61

Query: 227 NADEQFQCVK--GTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVD 370
             +E    +    T     A+ D   V E V E++ LK KV + +D V D
Sbjct: 62  TEEEMNAVLSRISTSTSHSALKDCDLVIEAVFEDVNLKLKVLREIDAVTD 111


>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
           Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
           dehydrogenase - Rhizobium loti (Mesorhizobium loti)
          Length = 309

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 33/112 (29%), Positives = 54/112 (48%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           + I+G G +G   A   A  G QV  +DV    I  A + + V    L+  G+   +   
Sbjct: 5   IAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPSAGV 64

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                 V+ T D+  AV  A  V E VPEN+ +K  V++ +D ++  +TI++
Sbjct: 65  G----TVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVA 112


>UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
           protein; n=5; Bacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase family protein - Silicibacter pomeroyi
          Length = 317

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 38/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVT--LFDVVEKQITDAIADIK-VQLKTLEKDGLLRG 220
           +V  +G G IG  WA  F + GY VT  L D  E+     I D   + L  L   GL  G
Sbjct: 11  RVTSIGGGPIGGGWAAHFLARGYDVTSYLHDRAEEGAFRTILDTAWISLTAL---GLAPG 67

Query: 221 NLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
                     ++   DL  AV  A F+QE  PENL +K+ ++  L  +V +N ++
Sbjct: 68  -----ASLDRLRVVHDLDAAVAGAGFIQESAPENLAMKQALYHRLGRIVPENVVI 117


>UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
           precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
           3-hydroxybutyryl-CoA dehydrogenase precursor -
           Acidobacteria bacterium (strain Ellin345)
          Length = 278

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 32/111 (28%), Positives = 53/111 (47%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           + ++G+G +GRS A   A  G++  L D++   +  A   I+ +L      G +     A
Sbjct: 7   IAVIGAGTMGRSIAQAAAVGGFRTILEDILPNALRKAEDAIRAELGRAVSTGSVE-QREA 65

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           D     ++   +L  A  DA  V E VP+ LE K ++F  LD V    T++
Sbjct: 66  DAALARIEYASNLEDAARDADMVIEAVPDELESKLEIFVLLDKVCRPETMI 116


>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
           n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
           precursor - Pseudomonas putida W619
          Length = 313

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 35/110 (31%), Positives = 60/110 (54%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 238
           ++G+GL+G   A +FA  G++V+L+D      T  +A  +V    L++ G+    + A+ 
Sbjct: 9   VIGAGLMGHGIAQVFAQAGHKVSLYD--PDAATLDLAPQRVA-HNLDQMGIASAPILAN- 64

Query: 239 QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               +    DL  AV +A  V E VPE LELK+K+F ++      +T+L+
Sbjct: 65  ----IALFTDLREAVSNADIVIEAVPERLELKQKLFADIAGFAPPHTVLA 110


>UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
           NAD-binding; n=2; Bacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase NAD-binding - Jannaschia sp. (strain CCS1)
          Length = 466

 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLL-R 217
           K  I+G G+IG  WA  F   G+ V ++D     E++I + + + +  L  L    L   
Sbjct: 2   KTAIIGGGVIGGGWAARFLLNGWNVAIYDPDPEAERKIGEVMDNARRALPGLYDTALPPE 61

Query: 218 GNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           G L         + T DL  AV DA +VQE VPE L++K KV   L  +     ++
Sbjct: 62  GTL---------RFTDDLGDAVGDADWVQESVPERLDIKHKVHAELTTLAPGRAVI 108


>UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
           NAD-binding; n=17; Bacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase NAD-binding - Silicibacter sp. (strain
           TM1040)
          Length = 491

 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 4/109 (3%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGLL 214
           ++   I+G G+IG  WA  F   G+ V +FD     E++I D +A+ +  L  L    L 
Sbjct: 2   TKTAAIIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGDVLANARRSLPGLGNVALP 61

Query: 215 -RGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLD 358
             G+L+  E          LA  V    +VQE VPE L+LK+KV+  L+
Sbjct: 62  PEGSLSYHET---------LAETVQGVDWVQESVPERLDLKQKVYAELE 101


>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 344

 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVG-YQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 223
           + + + G+GL+G   A + A  G + VTL DV +K + +    I   L  + K  +   +
Sbjct: 42  QNITVFGAGLMGAGIAQVLAHKGKFNVTLSDVTDKALANGQTIISKSLGRIVKKSMAEAS 101

Query: 224 LNADEQFQCVKG-------TCDLAIAVXDAIFVQECVPENLELKKKVFQNLD 358
             A+EQ Q VKG       T D   AV D   V E + EN+ +KK +F  LD
Sbjct: 102 --AEEQAQYVKGIVDSIKVTTDPEAAVKDTDLVIEAIIENVGIKKDLFGFLD 151


>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
           PlmT8 - Streptomyces sp. HK803
          Length = 571

 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 1/116 (0%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 223
           + ++G+VGSG +    A   A  GY  TL    E +  +A+A ++  L    + G L   
Sbjct: 290 ARRIGVVGSGTMATGIAQACARAGYPTTLVARSEVRAKEALATVENSLNRAVQRGRLTPE 349

Query: 224 LNADEQFQCVKGTCDL-AIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                  + + G   L A+A  D   V E V E++++K+ VF+ LD V    T+L+
Sbjct: 350 -QLTSSMESLTGVSRLEAVAACD--LVVEAVVEDIDVKRTVFRELDAVCGAQTVLA 402


>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Pelotomaculum thermopropionicum SI|Rep:
           3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
           thermopropionicum SI
          Length = 319

 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 33/112 (29%), Positives = 51/112 (45%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           + I+G+G +G S A      G  V L DV    +  A   I+  L +    G  +G    
Sbjct: 7   LAIIGAGTMGHSIAAAALQHGVSVRLIDVSAPALETARRKIQSYLASAAGKGGGKGGAVP 66

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                 ++   ++A  V  A  V E VPE L+LKK++F  LD +   + IL+
Sbjct: 67  GHLAGVLETCMEMAAGVTGADMVIEAVPEKLDLKKEIFAQLDKLCPPSVILA 118


>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
           protein; n=1; marine actinobacterium PHSC20C1|Rep:
           3-hydroxyacyl-CoA dehydrogenase-like protein - marine
           actinobacterium PHSC20C1
          Length = 288

 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 35/113 (30%), Positives = 53/113 (46%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           K+ +VGSG +G     L A  G  V +FDV E  +  A A +   L+   +   +    +
Sbjct: 5   KLAVVGSGTMGHGIGQLAAMQGIAVRVFDVDEVALDRARASVATSLERFVRKETITDAQS 64

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            + Q + +  T DL  A+       E VPE L LK+KVF +LD       +L+
Sbjct: 65  HEIQGR-MDWTTDLDAALVGVEAAIEAVPEVLALKQKVFTDLDERTGPEVMLA 116


>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
           n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
           putative - Aspergillus clavatus
          Length = 307

 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG--LLRGNL 226
           V ++G G++GR   M++A+ G+ V L+   EK    A+A +K   + L +    LL G  
Sbjct: 16  VAVIGGGVLGRRLCMMWAAAGHTVQLY---EKSPEVAVAALKYIHEALPQQASKLLLGK- 71

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            A      V     L  AV +A  V E +PE L LK ++F  LD +   + IL+
Sbjct: 72  KAGHGIGHVSPASSLETAVQNAWMVIEAIPELLPLKIELFGQLDQLAPADCILA 125


>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
           Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
           (strain EbN1))
          Length = 443

 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 33/113 (29%), Positives = 57/113 (50%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           +VG++G+G +G   AM FA+VG  VT+ D     +   +  ++   +     G L     
Sbjct: 43  RVGVIGAGTMGGGIAMSFANVGIPVTVCDTDGAALERGLERVRRNYEFSVARGRLDAATM 102

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           A  +   ++   DL   + DA  V E V E++ LK+ +F+ LD +V  + IL+
Sbjct: 103 A-ARLALIRAAVDLQ-DLKDADLVIEAVFEDMALKQDIFRKLDAIVHPDAILA 153


>UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
           Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
           - Rhodobacterales bacterium HTCC2654
          Length = 324

 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 33/113 (29%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI-TDAIADIKVQLKTLEKDGLLRGNL 226
           +V  +G G +G  WA +FA  G++V L+D     I   A+  I+  L+ L ++ +  G  
Sbjct: 3   RVVCIGVGTVGCGWATVFARAGHEVVLYDADADAIAARALPRIEATLEQLGRE-MPTGET 61

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
            AD + + ++    L  A+  A  VQE V E+L +K+ +F  +     D+ +L
Sbjct: 62  PADIRAR-IRVAGSLEEALSGAEVVQESVREDLAIKRALFDEIGAAAPDDCLL 113


>UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified
           Gammaproteobacteria (miscellaneous)|Rep: Enoyl-CoA
           hydratase - marine gamma proteobacterium HTCC2080
          Length = 699

 Score = 48.4 bits (110), Expect = 5e-05
 Identities = 34/112 (30%), Positives = 51/112 (45%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           VGI+G+G +G   AM FA  G  VTL D+ ++ +   +  I        K G L   +  
Sbjct: 296 VGIIGAGTMGGGIAMCFAQAGIAVTLVDMTDEAVKGGLEKIAKNYAISVKKGRL--TVAQ 353

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            +       T      + +   V E V ENLE+KK+VF  LD +     +L+
Sbjct: 354 TDAILANITTSSSFDDLANVDMVIEAVFENLEVKKEVFGKLDVICKPGAVLA 405


>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
           dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
           cellular organisms|Rep: 3-hydroxyacyl-CoA
           dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
           Aeropyrum pernix
          Length = 669

 Score = 48.0 bits (109), Expect = 6e-05
 Identities = 37/128 (28%), Positives = 68/128 (53%), Gaps = 7/128 (5%)
 Frame = +2

Query: 26  MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 205
           MA + K+  + +VG+G +G   A L A  G++V L D+    + +A+  I+  L+ L + 
Sbjct: 1   MAGEVKT--ITVVGAGTMGHGIAELAAIAGFKVYLADINIDILNNALQRIRWSLEKLAEK 58

Query: 206 GLLRGN----LNADEQFQCVKG---TCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNV 364
           G +R +    ++       V+    + DLA A+ ++ F+ E +PE LELK+++F   D  
Sbjct: 59  GRIRESVETVMSRITPIVSVRDGEYSEDLAKALSESDFMIEAIPEKLELKQQLFAFADKH 118

Query: 365 VDDNTILS 388
             +  IL+
Sbjct: 119 AKETAILA 126


>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=2; Sulfolobaceae|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
           Metallosphaera sedula DSM 5348
          Length = 334

 Score = 48.0 bits (109), Expect = 6e-05
 Identities = 30/108 (27%), Positives = 61/108 (56%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KV ++GSG++G     +FA  G++VTL+DV E+ +  A+  I+  L+ L++ G ++   +
Sbjct: 2   KVFVIGSGVMGSGIGQVFAMAGHEVTLYDVKEEALKKAMEGIRWSLQKLQEKGSVK---D 58

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDD 373
            +     +  + DL+ A  D + + E V E++++K  V   +  + D+
Sbjct: 59  VESVLSRIFTSRDLSEA-RDHLVI-EAVFEDIKVKSDVLGRVSPLTDE 104


>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
           shotgun sequence; n=3; core eudicotyledons|Rep:
           Chromosome chr11 scaffold_13, whole genome shotgun
           sequence - Vitis vinifera (Grape)
          Length = 724

 Score = 47.6 bits (108), Expect = 9e-05
 Identities = 31/114 (27%), Positives = 54/114 (47%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +KV ++G GL+G   A    +    V L +V  + +   I  I+  ++ L   G L  + 
Sbjct: 309 KKVAVIGGGLMGSGIATALITSNIYVVLKEVNSEYLLKGIKTIEANVRGLVTKGKLTQD- 367

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            A +    +KG  D +    D   V E V EN+ LK+K+F  ++ +   + IL+
Sbjct: 368 KARKALSMLKGVLDYS-EFKDIDMVIEAVIENISLKQKIFSEIEKICSPHCILA 420


>UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA
           dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
           COG1250: 3-hydroxyacyl-CoA dehydrogenase -
           Brevibacterium linens BL2
          Length = 314

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT-LEKDGLLRGNLN 229
           V ++G+G IGRS+A LFA  GY V +FD     + + + +++ ++        +L   L 
Sbjct: 5   VAVIGAGTIGRSFAWLFARSGYPVQVFD-PRPDLAEVVTELQAEVSADAAAHDMLASELG 63

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNL 355
                + V+       AV  A FVQE  PE+ + K K+F  +
Sbjct: 64  TISLAESVE------TAVAGASFVQESGPEDPQAKPKLFAQI 99


>UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24;
           Burkholderia|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 305

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 32/106 (30%), Positives = 53/106 (50%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           ++ IVG+G+IG SWA  + + G+ V   D   +      AD +++       G     L+
Sbjct: 5   RIAIVGAGVIGASWAAFYLTQGFDVVATDPAPQ------ADTRLRESLAAFLGERAAELS 58

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVV 367
           A   F       DL  A+    FVQE  PE L+LK+ +++ +D+V+
Sbjct: 59  ARLSFD-----ADLVRALDGVDFVQENGPERLDLKRALYRQMDDVL 99


>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
           hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
           3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
           hydratase/isomerasefamily protein - Croceibacter
           atlanticus HTCC2559
          Length = 802

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 14/133 (10%)
 Frame = +2

Query: 32  SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITD------AIADIKVQLKT 193
           +K +  K+ ++GSG++G   A  FA++G +V L D+V +++ +         + KV    
Sbjct: 2   AKRRINKIAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELNEKEKAKGLTLEDKVVRNR 61

Query: 194 LEKDGL---LRGN----LNADEQFQCVKGTCDLAIA-VXDAIFVQECVPENLELKKKVFQ 349
           +  D L   ++       + D   +   G  +  IA V D  ++ E V E L++KK+VF+
Sbjct: 62  IVNDALQSSIKSKPAPLYHKDFASRISTGNLEDDIAKVKDVDWIIEVVVERLDIKKQVFE 121

Query: 350 NLDNVVDDNTILS 388
           NL+    + T+++
Sbjct: 122 NLEKHRTEGTLIT 134


>UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:
           Dehydrogenase - Fusarium sporotrichioides
          Length = 285

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 35/111 (31%), Positives = 54/111 (48%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V ++G G++GR  A  +A+ GY V + D   +Q   A+      +     D  +RG++ A
Sbjct: 14  VAVLGGGVLGRRIACGWAASGYDVIIRDPSHEQRVAAVEYCNTSMSKYP-DSNVRGSIQA 72

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
            E         DL  AV  A  V E VPE L +K   F +L+ +  ++TIL
Sbjct: 73  VE---------DLPEAVAKAWLVIETVPEKLPIKIATFTDLERLTSEDTIL 114


>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
           isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
           Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
           isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
           radiodurans
          Length = 708

 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 28/114 (24%), Positives = 57/114 (50%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +  GI+G+G +G   AM F +VG  VT+ +  ++ +   +  I+   +   K G +  + 
Sbjct: 308 KSAGIIGAGTMGGGIAMNFLNVGIPVTIVETSQEALDRGLGVIRKNYENTAKKGRMTQD- 366

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           + +++   +  T  +   +  A  + E V EN+++KK +F  LD +     IL+
Sbjct: 367 DVEKRMGLLTPTLKME-DLAGADIIIEAVFENMDVKKDIFTRLDKIAKPGAILA 419


>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
           Blr6087 protein - Bradyrhizobium japonicum
          Length = 330

 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 8/120 (6%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDV-------VEKQITDAIADIKVQLKTLEKDGL 211
           +  +G+G +GR  A+ FA  G++VT+ DV         K  TDA+ +++    +L   GL
Sbjct: 7   IACLGAGRMGRGIAVAFAYAGHRVTMIDVKPRSAEDFAKLETDALGEVRKTFASLSNLGL 66

Query: 212 L-RGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           L   +++       V        A+ DA  V E VPE +ELK++V       V  +TI++
Sbjct: 67  LTEADVDPLVARVSVATASQSGTALADAGMVFEGVPEVVELKREVLGAASRQVKPDTIIA 126


>UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA
           hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
           enzyme; n=3; Bordetella|Rep: Probable enoyl-CoA
           hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
           enzyme - Bordetella pertussis
          Length = 705

 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 29/110 (26%), Positives = 54/110 (49%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 238
           +VG+G +GR  A+  A  G +V   DV +  +  A+  I+   ++L   G +     A +
Sbjct: 308 VVGAGTMGRGIAIALADAGLRVRFIDVEQASLDRALEAIRAHYRSLAARGRMT-EAAARD 366

Query: 239 QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               +    D+  A  +A  V E   E+L +K+ +F+ LD++V    +L+
Sbjct: 367 AVARISPASDMQ-AAAEADVVVEAAFEDLAIKQAIFRQLDSIVRPGAVLA 415


>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
           n=2; Bacteria|Rep: Fatty oxidation complex, alpha
           subunit - Salinibacter ruber (strain DSM 13855)
          Length = 719

 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 34/114 (29%), Positives = 54/114 (47%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + VG++G+GL+G   A + A  G  V L D       +    I   +   E  G++    
Sbjct: 319 DTVGVLGAGLMGSGIAQVSAQNGLDVVLTDQSLALAAEGKKAIWSAVTEQEDKGIIN-TF 377

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             D+  + V  T D A  +  A  V E VPE+L +K  V   ++ VVD +T+L+
Sbjct: 378 TRDQIVERVAPTADYA-PLQAADVVIEAVPEDLSIKHAVLSEVETVVDADTVLA 430


>UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
           n=1; Roseobacter denitrificans OCh 114|Rep: Putative
           3-hydroxyacyl-CoA dehydrogenase - Roseobacter
           denitrificans (strain ATCC 33942 / OCh 114)
           (Erythrobactersp. (strain OCh 114)) (Roseobacter
           denitrificans)
          Length = 331

 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 57/115 (49%), Gaps = 4/115 (3%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V I+G GLIG++WA +F   G +VTL+D     +  A A + ++  T       R +L  
Sbjct: 19  VAIIGCGLIGQAWATVFLRAGMRVTLYDAASGLVEQAKAQV-IERMT----EFARFDLVT 73

Query: 233 DEQFQCVKGTCDLAIAVXDAI----FVQECVPENLELKKKVFQNLDNVVDDNTIL 385
            E  +      +LA  + DA+    ++QE   E L++K ++ + +D     + ++
Sbjct: 74  HETLERAPAHIELADTLEDAVSAADYIQESGSEALDVKIELTREIDRFAAPHVVI 128


>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
           Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 298

 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 33/110 (30%), Positives = 48/110 (43%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 238
           I+GSG +G   A  FA  G+QV L D     +  A+  I   L+     G++  +   + 
Sbjct: 10  IIGSGTMGSGIAHSFAQFGFQVFLCDSNAAALNKAMLQISTNLERQISKGIIPDS-EKET 68

Query: 239 QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               +    D   A      V E VPE LE+K  +F+ LD      TIL+
Sbjct: 69  IISRITPITDFKEAAKTVSLVVEAVPELLEIKADLFKELDMHCPPETILA 118


>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
           organisms|Rep: Predicted protein - Ostreococcus
           lucimarinus CCE9901
          Length = 722

 Score = 46.8 bits (106), Expect = 1e-04
 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + VG+VG GL+G   A      G QV L ++ ++ +   +  I+  L ++ + G +  + 
Sbjct: 305 KSVGVVGGGLMGSGIATACLLAGIQVVLKEIKQEFLDAGVGRIQSNLTSMVRKGRMTED- 363

Query: 227 NADEQFQCVKGT-CDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            A +    VK T  D      D +   E V ENL LK+K+F  L+ +   + ILS
Sbjct: 364 KARQLMSLVKPTLTDQDFRQCDMVI--EAVIENLPLKQKIFCELERICKPDCILS 416


>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=12; Actinomycetales|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Arthrobacter sp. (strain FB24)
          Length = 723

 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 2/115 (1%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFA-SVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 223
           KVG+VG+GL+    A+LFA  +   V + D+ + ++   +  +  ++ K L K  +    
Sbjct: 350 KVGVVGAGLMASQLALLFARQLKVPVVMTDIDQARVDKGVGYVHAEVDKMLAKKRISADA 409

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            N  +    V G+     A  DA FV E V E L +KK+VF  ++ +V    IL+
Sbjct: 410 ANRTKAL--VTGSVS-KDAFADADFVIEAVFEELNVKKQVFAEVEAIVSPECILA 461


>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
           n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
           protein 1 - Caenorhabditis elegans
          Length = 299

 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 7/118 (5%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIK---VQLKTLEKDGLLRGN 223
           V I G+G++G   A +    GY V L+   EK++ +A   IK   +++ + +K  +    
Sbjct: 13  VAIFGAGMMGSGIAQVCLQAGYPVNLYGRSEKKLLEARETIKKNLIRVASKKKTDVPMEP 72

Query: 224 LNADE----QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
              +E    Q   ++   D+  A  DA    E V ENL+LK  +FQ +      N +L
Sbjct: 73  AALEEIAQIQLDLLQIHTDIPSAAEDAAMAIEAVAENLDLKLDIFQTIQKTCPQNCML 130


>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
           Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
           - Roseovarius sp. HTCC2601
          Length = 220

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 31/115 (26%), Positives = 54/115 (46%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 223
           S ++ +VG+G +G   A L+A  GY   + D         + D  V+       GL+  +
Sbjct: 13  SGRICVVGAGFMGCVIATLYAHHGYDAVICD-----SNQTMLDTYVERARPIAAGLVEDS 67

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             ++     V    DLA A+     V E V E+LE+K+ +F  L+ +  +N +L+
Sbjct: 68  DASEAMLAGVTLEPDLASAIEGVFLVHEAVQESLEVKQALFAELERICPENVVLA 122


>UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
          Length = 287

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 35/110 (31%), Positives = 54/110 (49%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 238
           +VG+G +G   A L A  G++V + D+  +    A A I+  L+   + G L      D 
Sbjct: 8   VVGAGNMGAGIAQLCAQQGFEVVIADISLELSDKAKARIEKGLRKRVEQGKLDA-AQKDA 66

Query: 239 QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               ++   DL  A     FV E V E++ +K+KVF  LDN+    TIL+
Sbjct: 67  ILSRIQTAGDLGPAAV-CRFVIESVIEDIAIKRKVFAELDNLSPPETILA 115


>UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG00090.1 - Gibberella zeae PH-1
          Length = 320

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 33/102 (32%), Positives = 49/102 (48%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V IVG G+IG  WA+LF S G +V + D  +     A   +K  L+        RGN   
Sbjct: 8   VAIVGCGVIGMGWAVLFMSCGLKVIISDPAD----GAHESLKRYLEQARSFFEERGNF-- 61

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLD 358
           D+     +   D+   + +  FVQE  PE +E K+ + + LD
Sbjct: 62  DKLSSNYEFVDDILPLLPEVDFVQENGPERVEFKQSLMEKLD 103


>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
           precursor; n=2; Alphaproteobacteria|Rep:
           3-hydroxybutyryl-CoA dehydrogenase precursor -
           Caulobacter sp. K31
          Length = 348

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 35/114 (30%), Positives = 54/114 (47%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + V ++G+GL+G   A +FA+ GY V LFD      T A   I   +  ++      G  
Sbjct: 47  QPVAVLGAGLMGAGIAKVFAAKGYPVFLFDRDLDTATSATRQINGAIAHVD------GGR 100

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           + D           LA AV DA FV E V E L++K+++F  L      + +L+
Sbjct: 101 DVD-------AAGSLAEAVADAAFVFESVSEKLDVKRRIFSALAECARHDAVLA 147


>UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
           protein; n=4; Brucella|Rep: 3-hydroxyacyl-CoA
           dehydrogenase family protein - Brucella suis
          Length = 501

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KV I+GSG++G   A   A+ G  V LFD    Q+ D  +  K+ L    +  + RG L 
Sbjct: 8   KVAIIGSGVMGAGIAETMAAGGIDVLLFD----QMADKASAAKLALSHRLQSRVERGKLG 63

Query: 230 ADEQFQCVKGTCDL--AIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           AD   Q ++    +     +  A  V E + ENL +KK +   L+ ++    +++
Sbjct: 64  ADRAAQILERIVPVQQLDEIVSADLVVEAIVENLTVKKDLVAALEAILPRQAVIA 118


>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
           precursor; n=5; Burkholderiales|Rep:
           3-hydroxybutyryl-CoA dehydrogenase precursor -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 511

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 30/110 (27%), Positives = 52/110 (47%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 238
           +VG+G++G   A + A  G+ V L+D  E    +A   +   L  L   G L       +
Sbjct: 17  VVGAGVMGVGIAQVAAQAGHAVMLYDAREGAAAEAKTKLAKSLDALVAKGKLTAQ-GVSQ 75

Query: 239 QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               ++    LA A   A  V E + E L++K+ +FQ L+ +V  + +L+
Sbjct: 76  TLSRIEAIASLA-AAAPARLVIEAIVEKLDVKRGLFQQLEAIVAADCVLA 124


>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
           hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
           n=6; Rhodobacterales|Rep: Enoyl-CoA
           hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
           Silicibacter pomeroyi
          Length = 698

 Score = 44.8 bits (101), Expect = 6e-04
 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 3/115 (2%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           +G++G G +G   A      G  VT+ ++  +    A   I+  L       L RG L A
Sbjct: 292 IGVIGGGTMGAGIATAALLSGLSVTMLEMTPEAAEAAKGRIEGNL----SGALKRGKLTA 347

Query: 233 DEQFQCVKGTCDLAI---AVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            +          LAI   A+ DA  V E V E++E+KK+VF  LD V     +L+
Sbjct: 348 QQFDNLTTKALTLAIDYDALADADLVIEAVFEDMEVKKQVFTKLDAVCKPGAVLA 402


>UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase
           NAD-binding; n=23; Alphaproteobacteria|Rep:
           3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
           sp. (strain CCS1)
          Length = 733

 Score = 44.8 bits (101), Expect = 6e-04
 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVE------KQITDAIAD--IKVQLKTLEK 202
           +KVGI+G+G++G   A + A  G +V L D  +      K  ++ + D  +K    T EK
Sbjct: 328 KKVGIIGAGMMGAGIAYVSALAGIEVVLIDAAQDSADRGKAYSEGLLDKGMKRGKVTEEK 387

Query: 203 DGLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNT 379
              + G + A   +  + G CDL   + +A+F    V   +  K +   N D +   NT
Sbjct: 388 KAKVLGQITATTDYDALNG-CDL---IVEAVFEDPKVKAEVTAKAEAAMNADGIFATNT 442


>UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB3;
           n=1; Mycobacterium ulcerans Agy99|Rep:
           3-hydroxybutyryl-CoA dehydrogenase FadB3 - Mycobacterium
           ulcerans (strain Agy99)
          Length = 294

 Score = 44.8 bits (101), Expect = 6e-04
 Identities = 35/116 (30%), Positives = 55/116 (47%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 220
           +S  V ++G+G +GR  A++FAS G  V ++    +Q   A   +   L  L +D   RG
Sbjct: 13  RSRPVAVIGAGTLGRRIALMFASRGGTVRIYARRAEQRAQATQYVADNLPKLLQD---RG 69

Query: 221 NLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                 +   V  T  LA A+  A    E VPE LE+K  ++  +D     +TI +
Sbjct: 70  ----FGEVGSVTATDCLATALEGAWLAVESVPEKLEIKTALWGQIDQAAPPDTIFA 121


>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
           precursor; n=1; Euglena gracilis|Rep:
           L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
           Euglena gracilis
          Length = 320

 Score = 44.8 bits (101), Expect = 6e-04
 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 7/119 (5%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLE----KDG---L 211
           VG+VG G +G   A + A+ GY+V   D+    ++  I  ++  L  +     KDG    
Sbjct: 25  VGVVGMGAMGHGIAQMTAAAGYKVVAVDIDANMLSKGIKAVEDSLSKVAAKAVKDGKADK 84

Query: 212 LRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                NA +    +  + D+  A+     V E + E+L +KKK F +L  V   N IL+
Sbjct: 85  ATAEKNAADVRSRITTSGDIG-ALSSCDLVIESIIEDLNIKKKFFADLGKVAGANAILA 142


>UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep:
           Enoyl-CoA hydratase - Rhodopseudomonas palustris
          Length = 699

 Score = 44.4 bits (100), Expect = 8e-04
 Identities = 32/113 (28%), Positives = 55/113 (48%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           +V I+G+G +G   AM FA+ G  VTL +  E+Q+   +  ++   +     G L  +  
Sbjct: 297 RVAIIGAGTMGGGIAMSFANAGIPVTLIETGEEQLKRGLGIMQKNWEATAARGGLPPDAP 356

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           A ++   + G   L   V DA  + E V E + +KK+VF  +D       +L+
Sbjct: 357 A-KRMALITGLVGLE-NVKDADLIIEAVFETMAVKKEVFTAVDAHAKPGAVLA 407


>UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
           protein; n=48; Bacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase family protein - Burkholderia mallei
           (Pseudomonas mallei)
          Length = 331

 Score = 44.4 bits (100), Expect = 8e-04
 Identities = 34/124 (27%), Positives = 51/124 (41%)
 Frame = +2

Query: 17  RVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTL 196
           R  MA   K +    +G+G+IG  W     + G  V  +D  E       A+++     L
Sbjct: 8   RKYMAVITKIDTFAAIGAGVIGSGWVARALANGLDVLAWDPAEDAEMQLRANVENAWPAL 67

Query: 197 EKDGLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDN 376
           E+ GL  G   A   F      C     V DA FVQE  PE   LK ++ + +      +
Sbjct: 68  ERAGLAPGASPARLHFVPTIEAC-----VADADFVQESAPEREALKLELHERISRAAKPD 122

Query: 377 TILS 388
            I++
Sbjct: 123 AIIA 126


>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
           Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
           Xenopus tropicalis
          Length = 666

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 32/113 (28%), Positives = 54/113 (47%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KVGIVG+G +G   AM FA+VG    + +V ++ +   +  ++   +     G L     
Sbjct: 292 KVGIVGAGTMGGGIAMNFANVGIPTVVVEVNDETLQRGLGLVRRNYEASAAKGRLTAEQV 351

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           A  +   ++G  D A A+ +   V E V EN+ LK+ +   L  V     I++
Sbjct: 352 AG-RMALLQGALDYA-ALAECDLVIEAVFENMALKQDICAKLGAVAKPGAIIA 402


>UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
           protein; n=3; Staphylococcus|Rep: 3-hydroxyacyl-CoA
           dehydrogenase family protein - Staphylococcus
           epidermidis (strain ATCC 35984 / RP62A)
          Length = 321

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 33/103 (32%), Positives = 47/103 (45%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           K  +VG+G+IG  W     + G++V   D  E      +  +K      E+ GL     N
Sbjct: 2   KFAVVGTGVIGSGWITRMLAHGHEVIATDPSEGAYERMLTQVKQNWPYAEQMGLAE---N 58

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLD 358
           A    Q +  T  L  AV DA  +QE VPE  E+K  V + +D
Sbjct: 59  AS--IQNLTFTPHLEEAVKDADHIQENVPEVEEIKDAVLKEID 99


>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
           cellular organisms|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - Burkholderia sp. (strain 383)
           (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
           R18194))
          Length = 284

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 223
           E VG+VG+G +G   A   A  G  V + DV +  +   IA +K  L + + KD L    
Sbjct: 4   EIVGVVGAGTMGNGIAQTAAVAGLNVVMIDVSDAALEKGIATLKGSLDRLVSKDKL--DA 61

Query: 224 LNADEQFQCVKGTCDLA-IAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
              D     +  + D A +A  D +   E   EN+ELK ++ + ++ V     I++
Sbjct: 62  ATRDAALARITTSTDYAKLAAADIVI--EAATENVELKGRILKQIEAVARAEAIIA 115


>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
           Lactobacillus reuteri F275
          Length = 294

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLF----DVVEKQITDAIADIKVQLKTLEKDGLL 214
           + + I G+G++G   A   A  G+ V+++    D  E++I    +D +  L   +K+   
Sbjct: 2   KNIMIAGAGVLGSQIAYQTALSGFNVSVYNHHIDTAERRIKALKSDYERDLHLTDKE--F 59

Query: 215 RGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +  LN  +       T D+A AV DA  + E +PE+LELK++ ++ +  +  + TI +
Sbjct: 60  QQGLNNIKVI-----TDDVATAVKDADLMIEALPESLELKEQFYEEVSELAPEKTIFA 112


>UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=2; Actinomycetales|Rep: 3-hydroxyacyl-CoA
           dehydrogenase, NAD-binding - Saccharopolyspora erythraea
           (strain NRRL 23338)
          Length = 303

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 33/110 (30%), Positives = 53/110 (48%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 238
           +VG+G IG  WA LF++ G +V + D       D +A +      L  + + R   + D+
Sbjct: 1   MVGAGTIGLGWAALFSAHGLEVRITDP-----RDDLASVVGDAMPLLAESMGR---DPDQ 52

Query: 239 QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               ++    LA AV DA  VQE  PE LE K+ +F ++        +L+
Sbjct: 53  LLAGIEIADSLADAVSDADLVQENGPERLEFKQDLFADIARHAPPRAVLA 102


>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
           protein; n=8; Mycobacterium tuberculosis complex|Rep:
           3-hydroxyacyl-CoA dehydrogenase family protein -
           Mycobacterium tuberculosis
          Length = 304

 Score = 43.6 bits (98), Expect = 0.001
 Identities = 35/108 (32%), Positives = 53/108 (49%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           +  +VG+GL+GR  A + AS G  V + D    +I  A A     ++     G  RG++ 
Sbjct: 9   RAAVVGAGLMGRRIAGVLASAGLDVAITDT-NAEILHAAA-----VEAARVAGAGRGSVA 62

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDD 373
           A           DLA A+ DA  V E V ENL +K+++F+ L  +  D
Sbjct: 63  A---------AADLAAAIPDADLVIEAVVENLAVKQELFERLATLAPD 101


>UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=1; Dinoroseobacter shibae DFL 12|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Dinoroseobacter shibae DFL 12
          Length = 391

 Score = 43.6 bits (98), Expect = 0.001
 Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDV---VEKQITDAIADIKVQLKTLEKDGL-LRGNL 226
           I+GSG IG  WA  F   G+ V +FD     + ++T  I   +  L  L    L   G L
Sbjct: 7   IIGSGRIGSGWAARFLLFGWHVRVFDADPGAQARLTQVIEAARTSLLGLYDTPLPPPGRL 66

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNL 355
           +             +A AV  A++VQE VPE+L LK++V + +
Sbjct: 67  SQHG---------SIAEAVAGAVWVQESVPEDLSLKREVVREV 100


>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
           hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
           dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
           symbiosum
          Length = 365

 Score = 43.6 bits (98), Expect = 0.001
 Identities = 27/94 (28%), Positives = 46/94 (48%)
 Frame = +2

Query: 77  IGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADEQFQCVK 256
           +G   A + A+ GY+V L D+ ++ +  A+  I+  L  +   G +      D     ++
Sbjct: 1   MGHGIAQVSAASGYEVVLRDIEQRFLDSAMEKIRWSLDKMASKGRITAE-EKDGILNRIR 59

Query: 257 GTCDLAIAVXDAIFVQECVPENLELKKKVFQNLD 358
               L  A+  A  V E VPE ++LK+KV+  LD
Sbjct: 60  PVVALGEALEGADLVIEAVPEVMDLKRKVYAELD 93


>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - Caulobacter sp. K31
          Length = 296

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 1/120 (0%)
 Frame = +2

Query: 32  SKFKSE-KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG 208
           S F  E K+G+VG+GL+G   A++FA  G  V L D     +  A+A +   L      G
Sbjct: 10  SPFAPELKIGVVGAGLMGAEIALVFALGGMDVLLHDRDAAALEKALARLSALLDRGVSRG 69

Query: 209 LLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           L      A    + ++   DL+    D   V E V E+LE+K +V   LD    +  +++
Sbjct: 70  LYTEGRRA-TALENIRLAPDLS-RFGDRDLVTEAVFESLEVKGQVLAALDEACPEACVIA 127


>UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase
           NAD-binding; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
           3-hydroxyacyl-CoA dehydrogenase NAD-binding -
           Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
           NCTC 12168)
          Length = 659

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 32/112 (28%), Positives = 54/112 (48%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           +GI G+GL+G   A+   + GY V  ++   +      A I   ++     G L     A
Sbjct: 297 IGIAGTGLMGSGIAVASLAAGYTVIGYETTAEAAAKGHARITDMIQKAVDTGRLSTEA-A 355

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           D Q   +  + D+A A+ DA  V E V ++  +K  +F+ LD ++   TIL+
Sbjct: 356 DAQRSKLSVSADMA-ALADADLVIEAVFDDFTVKASLFRELDALLPPATILA 406


>UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=5; Rhodobacteraceae|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Rhodobacter sphaeroides ATCC 17025
          Length = 673

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 29/113 (25%), Positives = 53/113 (46%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           ++G++G G +G   A   A+ G + TL +     +   I  ++   +     G L     
Sbjct: 292 RIGVIGGGTMGSGIAAAIAAAGLEATLAETGPDALEAGIKRVRAIFEAQVTRG-LTDRAG 350

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           A ++   V GT  L   + D   V E V E+L +K++VF++L  +   + IL+
Sbjct: 351 AADRLARVSGTVGLG-PLADCDLVIEAVFEDLAVKRRVFEDLTRLCRPDAILA 402


>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
           Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
           - Saccharopolyspora erythraea (strain NRRL 23338)
          Length = 517

 Score = 42.7 bits (96), Expect = 0.002
 Identities = 28/112 (25%), Positives = 52/112 (46%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V ++G+G++GR  A L A+ G  V L D  ++ ++ A+  +      L   G +     A
Sbjct: 11  VRVIGTGVMGRGIAQLAAAAGLTVELADARQEAVSAAVDHVGEMFGKLVGKGRMSAE-EA 69

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           D     ++   D          V E V E+L+ K+++F  L+ V   + +L+
Sbjct: 70  DAATARLRPVGDPLAPADSCDLVVEAVREDLDTKRELFAGLEEVCPRHAVLA 121


>UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3;
           Lactobacillales|Rep: Dihydrolipoyl dehydrogenase -
           Enterococcus faecalis (Streptococcus faecalis)
          Length = 469

 Score = 42.3 bits (95), Expect = 0.003
 Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGL 211
           E + I+G G+IG  WA L  S+G  VT+ + +++ + +  A I  +L K LE+ G+
Sbjct: 183 ESIAIIGGGVIGVEWASLLNSLGVNVTIIEFLDRLLINESATISKELKKRLEQRGI 238


>UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10;
           Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Frankia sp. (strain CcI3)
          Length = 624

 Score = 42.3 bits (95), Expect = 0.003
 Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           VG+VGSG +    A + A  G+ V L    E+ +   +A I+  L       + RG L+ 
Sbjct: 345 VGVVGSGTMAGGIAEVLARSGHDVLLRARSERTLAATLAKIESSLAA----SVARGRLSD 400

Query: 233 DEQFQC---VKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            ++      V+GT DL   +     + E V E+L +K+++F +LD +     +L+
Sbjct: 401 ADRLAALARVRGTTDLG-ELGHCELLLEAVVEDLAVKRELFADLDKIAAPGAVLA 454



 Score = 33.9 bits (74), Expect = 1.1
 Identities = 32/118 (27%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK-TLEKDGLLR 217
           +  +VG+VG G +G   A + A  G +V    V   +  DA+A  + +++ +L++ G   
Sbjct: 37  RHRRVGVVGLGTMGAGIAEVLAKAGLEV----VGIARDADALARSRARVEHSLDRAG-RH 91

Query: 218 GNLNADEQFQCVKGTCDLA---IAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 382
           G L+ D   + V     L     AV D   V E + E +  K+ +F  LD +    T+
Sbjct: 92  GKLD-DATREAVLARMRLGTELAAVADCELVIEAIDERMSAKQALFARLDEICPPATV 148


>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
           Serratia proteamaculans 568
          Length = 506

 Score = 42.3 bits (95), Expect = 0.003
 Identities = 26/113 (23%), Positives = 53/113 (46%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           +V ++G+G +G   A + A+ G+QV LFD+       A+  +  +L+     G  + +  
Sbjct: 9   RVAVIGAGTMGIGIAQVAAAAGHQVQLFDIAASAARQALGALAQRLRQRVAAG--KADAT 66

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             E         +   ++ D+  V E V E L +K+ +F+ L+ +    T+ +
Sbjct: 67  TTEALLARIQPAESLNSLADSGLVIEAVAEKLAIKQSLFRELEALCSPATLFA 119


>UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 310

 Score = 42.3 bits (95), Expect = 0.003
 Identities = 32/113 (28%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V ++G+GL+G   A   A  G +V L+D    Q  +   ++ +Q    +K+ L R  + A
Sbjct: 8   VAVIGAGLMGTCIAGELAYHGARVNLYD-RSAQAMEKSKEMLIQ----QKEQLKREEVMA 62

Query: 233 DEQFQCVKGTCD-LAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
              F      C+ L  AV ++  + E   ENLE+KK VF+++      N +++
Sbjct: 63  TSDFIGTVAFCESLEEAVVNSGLIFEATIENLEVKKSVFKSISQFCRTNAVIA 115


>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
           Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
           Brucella melitensis
          Length = 565

 Score = 41.9 bits (94), Expect = 0.004
 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 2/114 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           + IVG+G++G   A + A  G    +FD  E     ++  +   L  L +    +G ++A
Sbjct: 48  IAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASLDRLASTLAKLAE----KGKISA 103

Query: 233 DEQFQCVK--GTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           ++    V     C     + D   V E + E L+ K+ +F  L+ VV  N IL+
Sbjct: 104 EDAQTAVSRIEICSSIQELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILA 157


>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
           n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
           - Polyangium cellulosum (Sorangium cellulosum)
          Length = 293

 Score = 41.9 bits (94), Expect = 0.004
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 3/107 (2%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           VG+VG+G++G   A   A  G+ V L DV E  +  A   I+  L+ +   G       A
Sbjct: 12  VGVVGAGVMGVGVAQSLAQTGHDVVLVDVSEAALARARMGIRNGLRAVTLFGSAEDKKRA 71

Query: 233 DEQ---FQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNV 364
            +     + V  T D    +  A FV E V E  ++K++V+  L+ V
Sbjct: 72  GDPKAVLERVAFTTDYG-RLAGADFVVENVTEKWDIKREVYARLEGV 117


>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
           Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Rhodococcus sp. (strain RHA1)
          Length = 298

 Score = 41.9 bits (94), Expect = 0.004
 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 4/120 (3%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 220
           K ++VG++G+G++G   A + A     V +F+   +    A A     L++L++ G+  G
Sbjct: 5   KIQRVGVIGAGIMGAGIAEVCARAHVDVLVFEQTREL---AAAGRSRILRSLDR-GVSSG 60

Query: 221 NLNADEQFQC---VKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVV-DDNTILS 388
            +   E+ Q    ++ T DL     D   V E V E+ ++K ++F  LD VV D N +L+
Sbjct: 61  KITEREREQAAWRLRFTSDLG-DFADRQLVVEAVVEDEKVKSEIFTELDQVVTDPNAVLA 119


>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
           precursor; n=1; Geobacter lovleyi SZ|Rep:
           3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
           lovleyi SZ
          Length = 285

 Score = 41.5 bits (93), Expect = 0.006
 Identities = 28/112 (25%), Positives = 48/112 (42%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           +G+ G+G +G   A L A  G++V L+      + DA   I+  L  L + GL+      
Sbjct: 8   IGVAGAGSMGAGIAQLAAMAGFRVRLYARHASALADAAGRIETSLAKLHEKGLIG---EE 64

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               +     C   +A+ D   V E + E +  K ++   L  V+    IL+
Sbjct: 65  PTVIRARISNCHEPVALSDCDLVIEAIAEQMAAKCELLAELGAVLGKEAILA 116


>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
           Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
           Clostridium difficile
          Length = 281

 Score = 41.5 bits (93), Expect = 0.006
 Identities = 32/113 (28%), Positives = 51/113 (45%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           K+ ++GSG +G      FAS G+ V L    +  I   +A +   L  L   G       
Sbjct: 2   KLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKWMKATK 61

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           A E    V  T +    + D   + E   E++ +KK VF+ LD +  ++TIL+
Sbjct: 62  A-EILSHVSSTTNYE-DLKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILA 112


>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
           NAD-binding; n=1; Kineococcus radiotolerans
           SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
           NAD-binding - Kineococcus radiotolerans SRS30216
          Length = 681

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 31/117 (26%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFA-SVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLR 217
           K   VG+VG+GL+    A+L    +   V L DV   ++   +  ++  +  L + G + 
Sbjct: 317 KVTSVGVVGAGLMASQLALLLLHRLQVPVVLTDVSPDRVEKGVGFVREGVAELLRKGRVS 376

Query: 218 GNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            +  A+     V G+ D + A+ DA FV E V E L +K+ V + L+ ++  + +++
Sbjct: 377 PD-TANRLSASVSGSVDKS-ALADADFVVEAVFEELAVKQDVLRELEPLLRPDAVIA 431


>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
           Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
           - Legionella pneumophila (strain Corby)
          Length = 284

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 31/115 (26%), Positives = 50/115 (43%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 220
           K  K+ ++G+G +G     LFA  G+ VTL D ++ Q+  A   I   L  L     L  
Sbjct: 2   KQTKLTLLGAGTMGSGITQLFAQYGFYVTLIDNLQSQLDKAKDTIAKNLHYLALTQNLES 61

Query: 221 NLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
             + +     +  T  L   +  + ++ E + EN E KK ++Q L        IL
Sbjct: 62  THSIETILASITFTTKLD-ELKQSEYIIENITENWERKKALYQVLKKECSATCIL 115


>UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
           hydratase/isomerase family protein precursor; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep:
           3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
           hydratase/isomerase family protein precursor -
           Candidatus Desulfococcus oleovorans Hxd3
          Length = 801

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 8/124 (6%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEK---DGL 211
           K +K  ++GSG++G   A L AS G +  L D+V   +TD           + K   D +
Sbjct: 4   KIKKAAVIGSGVMGGGIAALLASAGVETLLLDIVPFDLTDEQKKDPAARNRIVKFGYDTI 63

Query: 212 LRGN-----LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDN 376
           +         ++D     +    D    + D  ++ E V ENL++K+++F+ ++ V    
Sbjct: 64  MMSRPAALMHSSDAALISIGNLEDDFDKLADCDWIVEVVVENLKIKQQLFKRIEPVRKKG 123

Query: 377 TILS 388
           +I+S
Sbjct: 124 SIIS 127


>UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=2; Alphaproteobacteria|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
           Paracoccus denitrificans (strain Pd 1222)
          Length = 765

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 32/114 (28%), Positives = 59/114 (51%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           EKV ++G+G++G   A   A+ G +V L DV +     A AD  ++ +  ++ G +    
Sbjct: 6   EKVAVLGAGVMGAGIAAHLANAGVRVVLLDVDK-----AAADAGIR-RARDEGGFMDPAF 59

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            A  +        DL++ + DA ++ E +PE L LK+ +++ L  +    +ILS
Sbjct: 60  AA--RIATGSTVRDLSL-LADADWIVEALPERLALKQSLYRQLQGIRKPGSILS 110


>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Shewanella woodyi ATCC 51908
          Length = 696

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
 Frame = +2

Query: 8   QTLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL 187
           Q L    +S      VG+VG+G +G   A  F   G  +   +  E+ +   + +++   
Sbjct: 293 QKLATSTSSTRTINTVGVVGAGNMGVGIARCFIDAGMDLIWIEQTEEALLRGMDNLRKGY 352

Query: 188 KTLEKDGLLRGNLNADEQFQCVKG-TCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNV 364
           ++    G +    + D++ Q VKG T    +A  D   V E   E+LE+KK +F+ LD  
Sbjct: 353 QSKITKGHMT-EQDLDDKMQLVKGSTVYDRLAPCD--LVVEAAFEDLEVKKIIFKALDQH 409

Query: 365 VDDNTILS 388
             D+ IL+
Sbjct: 410 CKDSAILA 417


>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
           mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
           Trifunctional enzyme alpha subunit, mitochondrial-like
           protein - Leishmania major
          Length = 726

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGNL 226
           +VG++G+G++G      FA     V + D+ E+ +   I +++ +  + + +  ++   L
Sbjct: 309 RVGVIGAGVMGSGIVHYFAKNNIPVAVKDLTEESVKQGITNVRAEFERAVRRKRMVTAEL 368

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLD 358
             D +   V G     +   DA  + E   E +++KKKV Q L+
Sbjct: 369 --DGKMALVTGGTTNEV-FRDADVIVEAAVEVMDIKKKVIQQLE 409


>UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Archaeoglobus fulgidus
          Length = 312

 Score = 41.1 bits (92), Expect = 0.007
 Identities = 28/105 (26%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ-LKTLEKDGLLRGNLN 229
           + ++G+G +G + A+LFA+ G++VTL D     +  A    + + L+ LE+ GL +    
Sbjct: 5   IAVIGAGTMGAAIALLFANAGFEVTLVDKSRGALRRAEDRHRGESLEELEEAGLRK---- 60

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNV 364
            D     +  T +L +   D  F+ E + E L  K ++F+ ++ +
Sbjct: 61  QDNPASLITYTTELRVYECD--FIVEAIVERLRDKIELFRKIEEI 103


>UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44;
           Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 710

 Score = 40.7 bits (91), Expect = 0.010
 Identities = 32/120 (26%), Positives = 52/120 (43%)
 Frame = +2

Query: 29  ASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDG 208
           AS    E++G+VG G +G   A+     G  VT+ +  E  +    A ++     L   G
Sbjct: 299 ASARPVERIGVVGGGTMGAGIAVSALDAGLPVTMIERDEASLARGRAHVEKVYDGLVAKG 358

Query: 209 LLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            +    +A    +   GT   A+A  D +   E V E++ +KK VF  L  V     +L+
Sbjct: 359 RMTPAAHAARLARFKGGTSYDALAQADVVI--EAVFEDMAVKKAVFAELARVCKPGAVLA 416


>UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=1; Mesorhizobium sp. BNC1|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Mesorhizobium sp. (strain BNC1)
          Length = 677

 Score = 40.7 bits (91), Expect = 0.010
 Identities = 30/102 (29%), Positives = 51/102 (50%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           ++G++G+G +G   A+   + G  V L D  +  +T A A +K  L  LE+ G L+    
Sbjct: 287 RLGVIGAGTMGVGLAVSLLAAGKSVVLIDKDDLALTRASAAVKSGLARLERGGKLKE--A 344

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNL 355
            D     +  + +L+ AV +   V E V E+ E+K  V  +L
Sbjct: 345 PDAALARLVASKELS-AVENCEVVIEAVVESFEVKSAVLSDL 385


>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Plesiocystis pacifica SIR-1
          Length = 733

 Score = 40.7 bits (91), Expect = 0.010
 Identities = 17/48 (35%), Positives = 30/48 (62%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK 190
           E+V I+G+G++G   A + A  GYQV L D+ ++ +   +A  + QL+
Sbjct: 333 ERVAILGAGMMGAGLAYICADAGYQVVLKDINQEALDKGVAHFEAQLR 380


>UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=14; Staphylococcus|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
           Staphylococcus aureus subsp. aureus JH9
          Length = 753

 Score = 40.7 bits (91), Expect = 0.010
 Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 1/103 (0%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFD-VVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           KV ++G+G +G   A LF + G +V L D VV+K   + IA  K   K  +K   L  +L
Sbjct: 5   KVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLIAK-KSYDKITDKKRPLLFDL 63

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNL 355
           N         G  D  +   DA    E V E++E+K  V+Q +
Sbjct: 64  NLVSHL--TYGNFDDDLVNDDADLYIEAVKEDIEIKHAVWQQV 104


>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - Nocardioides sp. (strain BAA-499 /
           JS614)
          Length = 275

 Score = 40.7 bits (91), Expect = 0.010
 Identities = 34/104 (32%), Positives = 49/104 (47%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 223
           S  + +VG G +GR  A+   + G++VTL DV E  +  A A +        +    RG 
Sbjct: 2   STSMVVVGGGTMGRGIAIAALATGFEVTLVDVAEDVLDRAQARVSEHFARHPQPD--RGV 59

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNL 355
           L+          T  LA ++  A  V E VPE L LK ++FQ L
Sbjct: 60  LHT---------TTSLAGSLETAEVVIEAVPEILPLKTQIFQQL 94


>UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1;
           Acinetobacter sp. DF4|Rep:
           3-hydroxyacyl-CoA-dehydrogenase - Acinetobacter sp. DF4
          Length = 240

 Score = 40.3 bits (90), Expect = 0.013
 Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 2/121 (1%)
 Frame = +2

Query: 32  SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 211
           +K+++ KVG++G+G++G   A   A  G  V L DV    + +A        K L+K  +
Sbjct: 123 TKWQATKVGVLGAGMMGAGIAYSTAIKGIPVVLKDV---SVENAEKGKAYSQKLLDK-RV 178

Query: 212 LRGNLNADEQFQCVKGTCDLAIA--VXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
            +G + A+++ Q +      A A  +     + E V EN ELK KV Q  +  +  N ++
Sbjct: 179 SQGRMTAEKRDQVLSLITATASAQDLQGCDLIIEAVFENQELKAKVTQEAEQYLAPNGVM 238

Query: 386 S 388
           +
Sbjct: 239 A 239


>UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
           Blastopirellula marina DSM 3645|Rep:
           3-hydroxybutyryl-coA dehydrogenase - Blastopirellula
           marina DSM 3645
          Length = 319

 Score = 40.3 bits (90), Expect = 0.013
 Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 2/111 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL-- 226
           VG+VG GL+GR       +  +QV  +D+  +    A A +   L+ L +   +   +  
Sbjct: 6   VGVVGLGLMGRGICTSLLANNFQVVAYDINPESFAAARAHVASALEELARHPSVAEAIPE 65

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNT 379
           N    FQ    T DL+  + D  FV E +PE+  +K++    L+ ++ ++T
Sbjct: 66  NWPSHFQL---TADLS-PLGDCDFVIESIPEDPVIKQETIAALERLLPNST 112


>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - Marinomonas sp. MED121
          Length = 545

 Score = 40.3 bits (90), Expect = 0.013
 Identities = 27/114 (23%), Positives = 53/114 (46%), Gaps = 2/114 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           +G+VG+G +G   A + +  G++V L+D    Q  +A    K  +  L    + +G +  
Sbjct: 17  IGVVGAGAMGAGIAQVASQAGHKVFLYD----QNEEASFRAKESISLLLNKKVAKGTITR 72

Query: 233 DEQFQCVKGTCDL--AIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +    C+     L     +  A  + E + E LE+K+ +F+ L+ +     IL+
Sbjct: 73  EHYDTCIANIIPLHSLDELKSADLIIEAIVETLEIKQSLFRALELICKPECILA 126


>UniRef50_A2QA05 Cluster: Catalytic activity:; n=4;
           Trichocomaceae|Rep: Catalytic activity: - Aspergillus
           niger
          Length = 622

 Score = 40.3 bits (90), Expect = 0.013
 Identities = 30/115 (26%), Positives = 51/115 (44%)
 Frame = +2

Query: 11  TLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLK 190
           T    +    KS  + I+G+G++GR  A +F+S GY V + D     +  A   I   + 
Sbjct: 3   TTNTTITHPSKSRPIVIIGAGILGRRIAAVFSSAGYSVHISDPSPSALDSARTYISTHIH 62

Query: 191 TLEKDGLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNL 355
                 + R +L+       +     +  AV  A  + E VPE L +K+ +F +L
Sbjct: 63  EFTTH-IPRPSLSPGP----ISTFTSVPEAVATAWLIVEAVPEILPIKQSLFADL 112


>UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3;
           Acholeplasmataceae|Rep: Dihydrolipoyl dehydrogenase -
           Acholeplasma laidlawii
          Length = 336

 Score = 40.3 bits (90), Expect = 0.013
 Identities = 23/68 (33%), Positives = 41/68 (60%), Gaps = 1/68 (1%)
 Frame = +2

Query: 11  TLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKV-QL 187
           T R ++  K   + + IVG G+IG  +A +F S G +VT+ ++++  +     DI+V   
Sbjct: 162 TSRELLNVKNYPKSIVIVGGGVIGVEFATVFNSFGSKVTIIEMMDGILPTMDDDIRVAYA 221

Query: 188 KTLEKDGL 211
           KTL++DG+
Sbjct: 222 KTLKRDGI 229


>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
           protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase family protein - Brucella suis
          Length = 509

 Score = 39.9 bits (89), Expect = 0.017
 Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 2/114 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           + IVG+G++G   A + A  G    +FD  E     A A  + +L +       +G ++A
Sbjct: 8   IAIVGAGVMGTGIAQIAAQAGLVTQIFDARE----GAAAASRDRLASTLAKLAEKGKISA 63

Query: 233 DEQFQCVK--GTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           ++    V     C     + D   V E + E L+ K+ +F  L+ VV  N IL+
Sbjct: 64  EDAQTAVSRIEICSSIQELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILA 117


>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
           FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
           oxidation complex, alpha subunit FadB - Blastopirellula
           marina DSM 3645
          Length = 724

 Score = 39.9 bits (89), Expect = 0.017
 Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 1/119 (0%)
 Frame = +2

Query: 35  KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLL 214
           K K E V ++G+G++G   A      G   TL D   + +   +A + ++    ++D   
Sbjct: 314 KTKIESVSVIGAGIMGAGIAAASIRRGILTTLSDANAEALRRGVAGV-LEEAAYDRDAGK 372

Query: 215 RGNLNADEQFQCVKGTC-DLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +    A E    +  +  D  +A    +   E + ENLE+K+K++  L+  + D+ IL+
Sbjct: 373 KTIAKAVEGAAMLNASISDSEVAASKLVI--EAIVENLEVKRKIYARLEPQLADDAILA 429


>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Mycobacterium smegmatis str. MC2 155|Rep:
           3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
           smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 296

 Score = 39.9 bits (89), Expect = 0.017
 Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 1/111 (0%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V ++G+G +G   A + A  G++  L+D+ E  +   I  +        + G L      
Sbjct: 12  VAVLGAGTMGSGIATVMARAGHRTILYDINEANLERGIDTVHGFFDKSVRLGKLDATAGQ 71

Query: 233 DEQFQCVKGTCDLA-IAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 382
             +   + G+ +L  +A  D   V E V E+L LKK+ F  LD++V   T+
Sbjct: 72  AAK-DSLSGSTELKDLAPCDV--VVEAVFEDLSLKKETFGRLDDIVPPTTL 119


>UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65;
           cellular organisms|Rep: Dihydrolipoyl dehydrogenase -
           Pseudomonas fluorescens
          Length = 478

 Score = 39.5 bits (88), Expect = 0.023
 Identities = 20/56 (35%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGL 211
           +K+G++G+G+IG     ++A +G +VT+ + ++K +  A   I K  LK L K GL
Sbjct: 182 KKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGL 237


>UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase;
           n=2; Bacillaceae|Rep: UDP-glucose:GDP-mannose
           dehydrogenase - Oceanobacillus iheyensis
          Length = 440

 Score = 39.1 bits (87), Expect = 0.030
 Identities = 16/40 (40%), Positives = 26/40 (65%)
 Frame = +2

Query: 38  FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQIT 157
           + + KVG++G G +G   A+LF   GYQVT  D+ + +I+
Sbjct: 12  YVNSKVGVIGMGYVGLPLALLFLKKGYQVTGIDINQSKIS 51


>UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Pelobacter carbinolicus DSM 2380|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
           / Gra Bd 1)
          Length = 304

 Score = 39.1 bits (87), Expect = 0.030
 Identities = 32/113 (28%), Positives = 50/113 (44%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           +V +VG G +GR  A   A+ GY VT++D+  + +      I      L  +G ++    
Sbjct: 8   QVLVVGGGTMGRQIAFQCAAHGYFVTIYDISAEVLQATQKRIGAYADYLVAEGHIQPQA- 66

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           A      +  + D A    +A  + E VPE+  LK +VF   D      TI S
Sbjct: 67  AKRAINRISISTD-ARQAANADLLCEAVPEDPALKGEVFARFDRYCPQRTIFS 118


>UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6;
           Clostridium|Rep: Dihydrolipoyl dehydrogenase -
           Clostridium oremlandii OhILAs
          Length = 467

 Score = 39.1 bits (87), Expect = 0.030
 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
 Frame = +2

Query: 5   LQTLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ 184
           + T   +++ K   +++ I+G G+IG  +A +F ++G +VT+F+     +     DI  +
Sbjct: 159 VMTSNELLSFKEIPKRLAIIGGGVIGIEFAGIFNALGSEVTVFEFAPSILIKLDKDISKR 218

Query: 185 LKT-LEKDGL 211
           L T L+KDG+
Sbjct: 219 LTTSLKKDGI 228


>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
           Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
           dehydrogenase-like - Geobacter metallireducens (strain
           GS-15 / ATCC 53774 / DSM 7210)
          Length = 290

 Score = 38.7 bits (86), Expect = 0.040
 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +KV I+G+G++G   A+  A  GY V L +V        +  I+  L    + G L   +
Sbjct: 5   KKVAILGAGMMGSDIALSCALAGYDVLLKEVSLDLAAAGVERIRGSLAKWSEKGRLA--V 62

Query: 227 NADEQFQCVK--GTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +A++Q   V      D      D   V E + E+L++K + F+ L+ V   + I++
Sbjct: 63  DAEQQKSAVARITPVDNFSGFGDVDLVIEAIFEDLDVKSQNFRQLEEVCKPSCIIA 118


>UniRef50_Q11E55 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
           Mesorhizobium sp. (strain BNC1)
          Length = 506

 Score = 38.7 bits (86), Expect = 0.040
 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
 Frame = +2

Query: 47  EKVGIVGSG-LIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRG 220
           +KV I G+G  +G   AM+ A  G+Q   FD   + +  +I   +    K++EK  +   
Sbjct: 5   KKVAICGAGGTMGAGIAMVAARAGFQTICFDQNGEALRRSIGAAEDFFRKSVEKGRMSPD 64

Query: 221 NL-NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +  NA  +        DLA    D   + E + ENLE K+++F++L+ +    TIL+
Sbjct: 65  DCDNALSRMTTSTNLKDLA----DCDLIIEAIFENLEAKQQLFRSLNEICKPETILA 117


>UniRef50_A6LMV1 Cluster: Putative uncharacterized protein
           precursor; n=1; Thermosipho melanesiensis BI429|Rep:
           Putative uncharacterized protein precursor - Thermosipho
           melanesiensis BI429
          Length = 208

 Score = 38.7 bits (86), Expect = 0.040
 Identities = 22/51 (43%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
 Frame = +2

Query: 35  KFKSEK-VGIVGSGLIGRSWAMLFASVGYQVTL-FDVVEKQITDAIADIKV 181
           K KS+K +GI G+GL+GR+ A L  + G+ V + FD  EK+I D    I +
Sbjct: 109 KLKSKKNIGIYGAGLVGRALAQLLLNRGFNVVVFFDDDEKKIGDRYLGIPI 159


>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=104; cellular organisms|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 736

 Score = 38.7 bits (86), Expect = 0.040
 Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
 Frame = +2

Query: 38  FKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDV-VE-----KQITDAIAD--IKVQLKT 193
           +++ KVG++G+G++G   A   A  G +V L DV VE     K  ++ + D  I     T
Sbjct: 322 YRAVKVGVLGAGMMGAGIAYSCARSGMEVVLKDVAVESAEKGKAYSEKLLDKAIAKGRST 381

Query: 194 LEKDGLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDD 373
            EK   L G + A      + G CDL I   +A+F      E+  LK++VF  +   VD 
Sbjct: 382 EEKKAELLGRITATADAADLAG-CDLVI---EAVF------EDPSLKQQVFAEIAPYVDQ 431

Query: 374 NTIL 385
           + +L
Sbjct: 432 DALL 435


>UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep:
           3-hydroxybutyryl-CoA dehydrogenase - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 304

 Score = 38.7 bits (86), Expect = 0.040
 Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 3/104 (2%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +KV I+G+G +G+    L A+ G++  ++D+    +  A    K +L+ L    + R  L
Sbjct: 10  KKVLILGAGSMGQQIGFLCAAKGFETAIYDLSPPLLDTA----KKRLEKLAGRFVSRHRL 65

Query: 227 NADEQFQC---VKGTCDLAIAVXDAIFVQECVPENLELKKKVFQ 349
             +E       V  T D   A  +A F+ E V E++E+K +VF+
Sbjct: 66  TGEEAAAAMARVTLTPDSEQAAANADFISESVTESVEIKCRVFE 109


>UniRef50_A3LNF8 Cluster: Kynurenine 3-monooxygenase, mitochondrial;
           n=3; Saccharomycetaceae|Rep: Kynurenine 3-monooxygenase,
           mitochondrial - Pichia stipitis (Yeast)
          Length = 478

 Score = 38.7 bits (86), Expect = 0.040
 Identities = 17/33 (51%), Positives = 25/33 (75%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDV 139
           + + VGIVG+GL+G   A+ FA+ GY VTLF++
Sbjct: 12  RHQGVGIVGAGLVGCLAALAFAAKGYSVTLFEL 44


>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
           cellular organisms|Rep: 3-hydroxybutyryl-CoA
           dehydrogenase - Bradyrhizobium japonicum
          Length = 293

 Score = 38.7 bits (86), Expect = 0.040
 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 2/116 (1%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL--KTLEKDGLLRG 220
           +KVG++G+G +G   A + A  G+ V L DV   ++   +A I   L  +  +K      
Sbjct: 6   KKVGVIGAGQMGNGIAHVAALAGFDVVLNDVSADRLKSGMATINGNLARQVSKKVVTEEA 65

Query: 221 NLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
              A  +    +   DLA    D   V E   E  E+K+K+F  L  V+    I++
Sbjct: 66  KTKALSRIVAAEKLDDLA----DCDLVIETAVEKEEVKRKIFHELCAVLKPEAIVA 117


>UniRef50_Q83EI9 Cluster: Thiamine biosynthesis oxidoreductase ThiO,
           putative; n=7; Legionellales|Rep: Thiamine biosynthesis
           oxidoreductase ThiO, putative - Coxiella burnetii
          Length = 338

 Score = 38.3 bits (85), Expect = 0.052
 Identities = 18/33 (54%), Positives = 23/33 (69%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEK 148
           KVGI G+GL+GR  A   + VG+ VTLFD  +K
Sbjct: 2   KVGIAGAGLLGRLLAWQLSKVGFGVTLFDKDDK 34


>UniRef50_Q6MHW5 Cluster: Glucose-inhibited division protein; n=1;
           Bdellovibrio bacteriovorus|Rep: Glucose-inhibited
           division protein - Bdellovibrio bacteriovorus
          Length = 440

 Score = 38.3 bits (85), Expect = 0.052
 Identities = 16/46 (34%), Positives = 30/46 (65%)
 Frame = +2

Query: 26  MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDA 163
           M +  +++K+ +VG+GL G   A+  A +GY V L+++ +K +T A
Sbjct: 1   MTNITQNQKITVVGAGLAGSECALQLADMGYSVVLYEMRDKTMTPA 46


>UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD
           binding domain; n=2; Azotobacter vinelandii|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD binding domain -
           Azotobacter vinelandii AvOP
          Length = 208

 Score = 38.3 bits (85), Expect = 0.052
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           + I+GSG +G   A   A  G++V L     +Q+ + +A  +  L      GL+     A
Sbjct: 6   IAILGSGSMGVGIATHLARHGHEVLLIYPSMEQLAEVLAMARSILA-----GLVEAGRFA 60

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQ---ECVPENLELKKKVFQNLDNVVDDNTILS 388
            EQ          +  + D   V+   E +PE +ELK+ ++  L+ +VD   +++
Sbjct: 61  PEQVAATLARLRTSTRLKDVAGVRLLIETLPERIELKRALYAELERIVDAEAVIA 115


>UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|Rep:
           Oxidoreductase - Lactococcus lactis
          Length = 449

 Score = 38.3 bits (85), Expect = 0.052
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
 Frame = +2

Query: 23  VMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLE 199
           +M  K   E + I+GSG IG  +A +FAS G +VT+ D+ +  +     DI K+    LE
Sbjct: 155 LMDLKQLPEHLTIIGSGYIGLEFASMFASYGSKVTVLDIFDNFLPRDDEDISKLVRSDLE 214

Query: 200 KDGLL 214
             G++
Sbjct: 215 SRGII 219


>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
           dehydrogenase, NAD-binding - Burkholderia phytofirmans
           PsJN
          Length = 317

 Score = 38.3 bits (85), Expect = 0.052
 Identities = 29/112 (25%), Positives = 53/112 (47%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           +G+VG+GL+G   A   A  G++  + DV   ++       +  L  L   G +      
Sbjct: 19  IGVVGTGLMGVGIATQSALHGHRTIVHDVDPARLASVAPKAQAVLDELIDAGRIDPAAK- 77

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                 ++   +L + +  A FV E +PE LELK +++  L  ++ D+ IL+
Sbjct: 78  QAALARIETHAELDV-MASAQFVIEAIPEVLELKHRLYAALTQLLADDAILA 128


>UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13;
           Bacillus|Rep: Dihydrolipoyl dehydrogenase - Bacillus
           subtilis
          Length = 458

 Score = 38.3 bits (85), Expect = 0.052
 Identities = 21/52 (40%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGL 211
           IVG G+IG  +A LFA +G QVT+ +  ++ I     DI ++  + LE+DG+
Sbjct: 175 IVGGGVIGCEYAGLFARLGSQVTIIETADRLIPAEDEDIARLFQEKLEEDGV 226


>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
           Blr2428 protein - Bradyrhizobium japonicum
          Length = 715

 Score = 37.9 bits (84), Expect = 0.069
 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKDGLLRGNLN 229
           V ++G+G +G   A   A  G +V+L D+  + I  A+    ++  K + K   +R  L 
Sbjct: 343 VHVIGAGAMGGDIAAWCAGQGLRVSLADMKAEPIAGAVKRAAELYGKIIRKPTEVRDAL- 401

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            D     + G       V +A  V E VPE LELK+KV+  L+  +    IL+
Sbjct: 402 -DRLIPDMDGE-----GVRNADLVIEAVPEKLELKQKVYAGLEPKMKPGAILA 448


>UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Hahella chejuensis (strain KCTC 2396)
          Length = 283

 Score = 37.9 bits (84), Expect = 0.069
 Identities = 26/112 (23%), Positives = 49/112 (43%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           + ++G G IG S A   A  G+ V + +  E     + A +            L      
Sbjct: 6   IAVIGGGNIGSSLAFDCALRGHNVVVVEKDEPSCEQSRARVLETAGYAPLFSPLAKGKKP 65

Query: 233 DEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            +    ++ + +L  A+ D  FV E +PEN+ELK+ ++  +   +  N +L+
Sbjct: 66  QDILDNIRWSNELG-AISDCAFVVENIPENIELKQALYTRMAEFIAPNAVLA 116


>UniRef50_Q2GH13 Cluster: FAD-dependent oxidoreductase; n=6;
           Anaplasmataceae|Rep: FAD-dependent oxidoreductase -
           Ehrlichia chaffeensis (strain Arkansas)
          Length = 354

 Score = 37.9 bits (84), Expect = 0.069
 Identities = 16/31 (51%), Positives = 23/31 (74%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFD 136
           ++K G+VG+GL+GR  A+     G+QVTLFD
Sbjct: 2   NKKAGVVGAGLVGRLLALRLLHDGWQVTLFD 32


>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
           dehydrogenase; n=65; Bacteria|Rep: Probable
           3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
          Length = 287

 Score = 37.9 bits (84), Expect = 0.069
 Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 1/115 (0%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL-KTLEKDGLLRGN 223
           +++ + G+G +G   A   A  G+ V ++DV  +     +  +K QL +  EK       
Sbjct: 4   KQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKRLKKQLARDAEKGKRTETE 63

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           + +      +  T + A     A  V E + EN+  K ++F+ LD +   +TIL+
Sbjct: 64  VKSVINRISISQTLEEA---EHADIVIEAIAENMAAKTEMFKTLDRICPPHTILA 115


>UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine
           nucleotide-disulfide, class I; n=29; Bacteria|Rep:
           Oxidoreductase, pyridine nucleotide-disulfide, class I -
           Streptococcus pneumoniae
          Length = 438

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT-LEKDGL-LRG 220
           EK+GI+G G IG  +A L+  +G +VT+ D ++  +  A   I    K  +E+DG+ L  
Sbjct: 158 EKLGILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQ 217

Query: 221 NLNADE 238
           N++  E
Sbjct: 218 NIHTTE 223


>UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1;
           Clostridium acetobutylicum|Rep: 3-Hydroxyacyl-CoA
           dehydrogenase - Clostridium acetobutylicum
          Length = 379

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 27/116 (23%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           ++GI+G G +GR      +   Y+V L     +Q+ +  + I+ QL+       L+ NL 
Sbjct: 2   EIGIIGKGKMGRDIFNYISMFDYKVILICRQAEQVEEVKSSIEKQLRK-----KLKRNLI 56

Query: 230 ADEQFQCVKGTCDLAIAVXD---AIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            +E++   K    +   + D      + E + E+  LK+ +  +++ +V D  IL+
Sbjct: 57  TEEEYNSKKDAYKVTDNIQDLKNCDIIIEAIYEDEVLKQNILGDVEKIVKDECILA 112


>UniRef50_A6TSA3 Cluster: Amine oxidase; n=1; Alkaliphilus
           metalliredigens QYMF|Rep: Amine oxidase - Alkaliphilus
           metalliredigens QYMF
          Length = 570

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 18/51 (35%), Positives = 28/51 (54%)
 Frame = +2

Query: 2   PLQTLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI 154
           P    ++  A   K  KVGI+G GL G S A     +G+ +T+F+  E++I
Sbjct: 41  PQDITKINPAGSCKHIKVGILGGGLAGLSAAFELRKLGFDITIFEAEEERI 91


>UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=1; Sphingomonas wittichii RW1|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Sphingomonas wittichii RW1
          Length = 322

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 31/115 (26%), Positives = 47/115 (40%), Gaps = 4/115 (3%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           V  +G G+IG  W   F   G  V L D        A A I+  +          G   A
Sbjct: 13  VAAIGGGVIGGGWVAAFLGSGRAVRLHDPAP----GAEARIRAHVTQAWPQMAALGLARA 68

Query: 233 DEQFQCVKGTCDLAIAVXDAI----FVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           D+ +    G       + DA+    FVQE  PE  ++K+ +F  LD +V  + ++
Sbjct: 69  DDDWT---GRLSFHETIEDAVEGTDFVQENTPERSDVKRALFAELDRLVPADVLV 120


>UniRef50_A3XPY3 Cluster: Putative uncharacterized protein; n=1;
           Leeuwenhoekiella blandensis MED217|Rep: Putative
           uncharacterized protein - Leeuwenhoekiella blandensis
           MED217
          Length = 262

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 18/40 (45%), Positives = 25/40 (62%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIA 169
           K+GI+G+GLIG++ A  F + G+QV L D       D IA
Sbjct: 2   KIGIIGAGLIGKTLAKKFNAAGHQVKLGDAKGAASIDTIA 41


>UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Verminephrobacter eiseniae EF01-2|Rep: 3-hydroxyacyl-CoA
           dehydrogenase - Verminephrobacter eiseniae (strain
           EF01-2)
          Length = 319

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 26/110 (23%), Positives = 51/110 (46%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 238
           ++G+G++G   +   A  G  V ++D+ E+ +    A         + D +     +   
Sbjct: 9   VLGAGVLGGQISWHSAFKGKSVVVYDISEEALARCRAAQAHYAAIYQTDAVGASEADVAG 68

Query: 239 QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             Q +    DLA AV  A  V E VPE  ++K  V+Q +  ++  +T+++
Sbjct: 69  ARQRLTFATDLASAVASADLVIEAVPEIPQVKTSVYQQMAPLLPAHTLIA 118


>UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
           3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
           Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
          Length = 681

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 2/115 (1%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFAS-VGYQVTLFDVVEKQITDAIADIKVQLKTL-EKDGLLRGN 223
           KVGIVG+GL+    A LF   +   V + D+  + +      +    + L EK  L  G 
Sbjct: 318 KVGIVGAGLMASQLAQLFIERLEVPVVMKDISPEALEKGCGQVVEGFRRLGEKGKLTEG- 376

Query: 224 LNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             A      V GT D      D  FV E V E + +KK+V   L+ ++  + +++
Sbjct: 377 -KARHLAGLVSGTLDFR-DFSDCDFVIEAVFEEMAVKKQVLGELEPLLRPDAVIA 429


>UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;
           n=4; Caenorhabditis|Rep: Putative uncharacterized
           protein ech-8 - Caenorhabditis elegans
          Length = 437

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 8/120 (6%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLE--------K 202
           + V ++G G +GR  A+ F   G++  L +V  K       ++++  K  +        K
Sbjct: 40  KSVAVIGGGTMGRGIAIAFCLSGFETYLVEVNNKAAEFCKNELEITYKREKAFRRLNDSK 99

Query: 203 DGLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 382
              LR NL     FQ +   CDL   + +A+F      E+++LKK++F  LD +   + I
Sbjct: 100 VEKLRKNLQITTDFQKL-NNCDL---IVEAVF------EDMKLKKELFTKLDKICKPSCI 149


>UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 308

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 27/112 (24%), Positives = 53/112 (47%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           KV ++G+G IG S+A       + +      +  I D  +D+   ++         G   
Sbjct: 7   KVTLIGTGTIGLSFA------AFHLAKLSPSQLTIYDTRSDLSTYIEEFLPKFFESGKSP 60

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           AD     ++    L  AV D+  +QE  PENL++K+K+++ ++    ++ +L
Sbjct: 61  AD--LSEIRLAVTLQEAVSDSHIIQESGPENLDVKRKLWKEVEKYAPNDALL 110


>UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4;
           Thermococcaceae|Rep: NDP-sugar dehydrogenase -
           Pyrococcus furiosus
          Length = 434

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 18/46 (39%), Positives = 27/46 (58%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQL 187
           K+ ++G G IG   A++FA  GY+V  FD V+K + D I   K  +
Sbjct: 18  KIAVIGLGYIGLPTAIMFAEAGYEVIGFD-VKKDVVDRINSGKAHI 62


>UniRef50_P38169 Cluster: Kynurenine 3-monooxygenase; n=4;
           Saccharomycetales|Rep: Kynurenine 3-monooxygenase -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 460

 Score = 37.5 bits (83), Expect = 0.091
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFD 136
           SE V I+G+GL+G   A+ F+  GY VTL+D
Sbjct: 2   SESVAIIGAGLVGCLAALAFSKEGYNVTLYD 32


>UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;
           n=2; Proteobacteria|Rep: Fatty oxidation complex, alpha
           subunit - Sphingomonas sp. SKA58
          Length = 722

 Score = 37.1 bits (82), Expect = 0.12
 Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 3/121 (2%)
 Frame = +2

Query: 35  KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFD---VVEKQITDAIADIKVQLKTLEKD 205
           KF+++KVG++G+G++G   A + A+ G  V L D      ++  D  A  KV  K +EK 
Sbjct: 310 KFEAKKVGVLGAGMMGAGIAFVSANAGIDVVLIDRDTATAQKGKDYSA--KVLGKLVEKG 367

Query: 206 GLLRGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
            L +    AD     +  T D A+ +     V E V E+  +K +  +  + V+    I 
Sbjct: 368 KLTQD--KADAVLARITPTDDFAL-LDGCDMVVEAVFEDTAIKAETTKKAEAVLPAQAIF 424

Query: 386 S 388
           +
Sbjct: 425 A 425


>UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
           Reinekea sp. MED297|Rep: 3-hydroxyacyl-CoA dehydrogenase
           - Reinekea sp. MED297
          Length = 705

 Score = 37.1 bits (82), Expect = 0.12
 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 2/115 (1%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLN 229
           ++G+VG+G++G   A   AS G  V L D  + +        K   + L      RG L+
Sbjct: 315 RIGVVGAGMMGAGIAWACASKGLPVVLVDTEQSRAEQG----KGYSERLVAKRFERGRLS 370

Query: 230 ADEQFQCVK--GTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           A+E    +      +    + +   V E V E+  LK  V+Q + +VV   TI++
Sbjct: 371 AEEGTALLNRITPTESMSELAECDLVIEAVFEDRALKADVYQLIQSVVSPETIIA 425


>UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 508

 Score = 37.1 bits (82), Expect = 0.12
 Identities = 19/44 (43%), Positives = 27/44 (61%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIAD 172
           K EK+ ++G G +G   A+LFA VG  V+L D  E Q  DA+ +
Sbjct: 3   KFEKIAMIGCGSMGGGMALLFAEVGVHVSLSDPSE-QAMDAVIE 45


>UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema
           pallidum|Rep: D-lactate dehydrogenase - Treponema
           pallidum
          Length = 331

 Score = 37.1 bits (82), Expect = 0.12
 Identities = 16/38 (42%), Positives = 26/38 (68%)
 Frame = +2

Query: 23  VMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFD 136
           +++ + +  +VGI+G+G IG++ A LF  VG QV  FD
Sbjct: 139 ILSKELRCSRVGILGTGRIGQAAARLFKGVGAQVVGFD 176


>UniRef50_Q485S6 Cluster: Putative D-amino acid dehydrogenase, small
           subunit; n=1; Colwellia psychrerythraea 34H|Rep:
           Putative D-amino acid dehydrogenase, small subunit -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 427

 Score = 36.7 bits (81), Expect = 0.16
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFD 136
           K + V ++G+G+IG + A+   S+GYQVTL D
Sbjct: 12  KQQTVAVIGAGIIGINCALELQSLGYQVTLLD 43


>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep:
           3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 287

 Score = 36.7 bits (81), Expect = 0.16
 Identities = 28/112 (25%), Positives = 54/112 (48%), Gaps = 1/112 (0%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNA 232
           VG++G+G +G     + A  GY+V   D  E+ +  A   ++  L++  + G L     A
Sbjct: 5   VGVLGTGTMGAGIVQVAARAGYRVVACDASEEALGKARRYVRSGLESFARRGAL-SEEEA 63

Query: 233 DEQFQCVKGTCDL-AIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTIL 385
           +     V+ T  +  +A  +A+   E + E +  KK+ F  LD ++  + +L
Sbjct: 64  EAALGRVRWTTAMEELAGSEAVI--EAIVERVGPKKEAFAALDALLPPDALL 113


>UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA
           dehydrogenase and acyl-CoA-binding protein; n=11;
           Francisella tularensis|Rep: Fusion product of
           3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding
           protein - Francisella tularensis subsp. tularensis
           (strain FSC 198)
          Length = 898

 Score = 36.7 bits (81), Expect = 0.16
 Identities = 26/114 (22%), Positives = 52/114 (45%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +K+ ++G+G +G   A  FA+  + V LFD+  +Q   A   I+  L  L K        
Sbjct: 118 DKIAVLGAGTMGAQIAAHFANAKFPVVLFDLKSQQ-GSANVIIEDSLAKLTKLNPAPFGS 176

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               ++       D    + D   + E V E +++K+ ++  + + + +N IL+
Sbjct: 177 KDSIKYITPANYEDNLELLADCDLIIEAVAERIDIKESLYTKISSHIKENAILA 230


>UniRef50_Q0TSZ8 Cluster: Transcriptional regulator, MarR family;
           n=2; Clostridium perfringens|Rep: Transcriptional
           regulator, MarR family - Clostridium perfringens (strain
           ATCC 13124 / NCTC 8237 / Type A)
          Length = 147

 Score = 36.7 bits (81), Expect = 0.16
 Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGY-QVTLFDVVEKQITDAIADIKVQLKTLEKDGLLR 217
           K E   I  SGL    + +L A      + + +++EK +T +  +I V +K LEKDGL++
Sbjct: 30  KKEFQTIKESGLTIAQFGVLEALYNKGDLRICEIIEKILTTS-GNITVVIKNLEKDGLVK 88

Query: 218 GNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNL 355
            N + +++  C+    D    V     ++  +P ++   K +F+ L
Sbjct: 89  KNADPEDKRSCIISLTDEGRKV-----IENILPSHINNIKNIFEVL 129


>UniRef50_Q1FP37 Cluster: NADH:flavin oxidoreductase/NADH
           oxidase:FAD-dependent pyridine nucleotide-disulphide
           oxidoreductase:Acetoacetate decarboxylase; n=1;
           Clostridium phytofermentans ISDg|Rep: NADH:flavin
           oxidoreductase/NADH oxidase:FAD-dependent pyridine
           nucleotide-disulphide oxidoreductase:Acetoacetate
           decarboxylase - Clostridium phytofermentans ISDg
          Length = 937

 Score = 36.3 bits (80), Expect = 0.21
 Identities = 17/44 (38%), Positives = 25/44 (56%)
 Frame = +2

Query: 32  SKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDA 163
           S  K EKV ++G+GL G   A      G QVT+ D+++K   +A
Sbjct: 512 SALKGEKVAVIGAGLTGLETAEYLFEEGNQVTIIDMLDKPAPNA 555


>UniRef50_A3D4X7 Cluster: FAD dependent oxidoreductase; n=3;
           Shewanella baltica|Rep: FAD dependent oxidoreductase -
           Shewanella baltica OS155
          Length = 578

 Score = 36.3 bits (80), Expect = 0.21
 Identities = 17/40 (42%), Positives = 26/40 (65%)
 Frame = +2

Query: 20  VVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDV 139
           +++ S  KS+ V I G G+ G + A  FA +GYQV +F+V
Sbjct: 16  LLIKSSTKSKSVAIFGGGIAGLTAAHEFAKLGYQVKVFEV 55


>UniRef50_A1SV61 Cluster: FAD dependent oxidoreductase precursor;
           n=4; Proteobacteria|Rep: FAD dependent oxidoreductase
           precursor - Psychromonas ingrahamii (strain 37)
          Length = 491

 Score = 36.3 bits (80), Expect = 0.21
 Identities = 14/37 (37%), Positives = 25/37 (67%)
 Frame = +2

Query: 26  MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFD 136
           M +  KS+K+ I+G G+ G S A+  + +G +V+LF+
Sbjct: 1   MVNSQKSKKIAIIGGGIAGASVALYLSEIGLEVSLFE 37


>UniRef50_Q6KCB6 Cluster: Dihydrolipoyl dehydrogenase; n=8;
           Plasmodium|Rep: Dihydrolipoyl dehydrogenase - Plasmodium
           falciparum
          Length = 512

 Score = 36.3 bits (80), Expect = 0.21
 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEK 202
           + I+G G+IG     +F+ +G  VT+F+  E+      AD+ KV  KTLEK
Sbjct: 214 ISIIGGGVIGLEIGSVFSKLGSDVTVFEYNERLCGFLDADVSKVLQKTLEK 264


>UniRef50_A7TI21 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 465

 Score = 36.3 bits (80), Expect = 0.21
 Identities = 16/31 (51%), Positives = 20/31 (64%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFD 136
           SE VGI+G+G +G    +  A  GY VTLFD
Sbjct: 2   SESVGIIGAGPVGCLTGLFLAQKGYDVTLFD 32


>UniRef50_Q82W31 Cluster: Phosphoribosylaminoimidazole carboxylase,
           ATPase subunit; ATP-grasp domain; n=2;
           Proteobacteria|Rep: Phosphoribosylaminoimidazole
           carboxylase, ATPase subunit; ATP-grasp domain -
           Nitrosomonas europaea
          Length = 376

 Score = 35.9 bits (79), Expect = 0.28
 Identities = 17/53 (32%), Positives = 29/53 (54%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 211
           +G++G G +GR +AM    +GY+VT+ D   +    +IA+  +Q   L    L
Sbjct: 9   LGLLGGGQLGRMFAMAAQQMGYRVTVLDPAAESPAGSIAERHLQADYLNDQAL 61


>UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA
           dehydrogenase,possibly related to diterpenoid
           metabolism; n=6; Proteobacteria|Rep: DitN-like
           3-hydroxyacyl-CoA dehydrogenase,possibly related to
           diterpenoid metabolism - Azoarcus sp. (strain EbN1)
           (Aromatoleum aromaticum (strain EbN1))
          Length = 299

 Score = 35.9 bits (79), Expect = 0.28
 Identities = 26/114 (22%), Positives = 48/114 (42%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           EK+ +VG+GL+G   A   A  GY++ L D     +  A+  I   +    K G L    
Sbjct: 5   EKIIVVGAGLMGTGIAYSCAISGYRILLVDANPSALDKAVGQINSLVAAGVKLGKL-VEA 63

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
                 + ++   +L     DA  + E   E +++K  +    D ++    I++
Sbjct: 64  AGKAALERLEAAIELDGRASDAALLIETATEKIDIKLAIIGKADELLPPEAIIA 117


>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
           domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase, C-terminal:3-hydroxyacyl-CoA
           dehydrogenase, NAD binding domain - Azotobacter
           vinelandii AvOP
          Length = 307

 Score = 35.9 bits (79), Expect = 0.28
 Identities = 30/110 (27%), Positives = 50/110 (45%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNLNADE 238
           I+G+GL+G   A   A  G+ V L D   +++ +        L  L   G        D 
Sbjct: 8   ILGAGLMGIGIATHLARHGHAVLLRDPAAERLAEVPVMAGSILAELADAGRFE-RAQTDA 66

Query: 239 QFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
               +  +  LA  V DA  + E +PE LELK+ ++  L+ +V   T+++
Sbjct: 67  TLARLAVSPRLA-DVADARLLIEAIPERLELKRALYAELEALVGTGTVIA 115


>UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
           NAD-binding; n=4; Alphaproteobacteria|Rep:
           3-hydroxyacyl-CoA dehydrogenase NAD-binding -
           Silicibacter sp. (strain TM1040)
          Length = 733

 Score = 35.9 bits (79), Expect = 0.28
 Identities = 27/117 (23%), Positives = 57/117 (48%), Gaps = 3/117 (2%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +K+G++G+G++G   A++ A  G +V L D    +  DA    K    T    G+ RG  
Sbjct: 327 KKIGVLGAGMMGAGIALVSAQAGMEVVLID----RDQDAADKGKAYSATYMDKGIKRGKA 382

Query: 227 NADEQ---FQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             +++      +  T DL  A+     + E V E+  +K ++ + ++ ++ ++ I +
Sbjct: 383 TPEKKEALLAQITATADLD-ALKGCDLIIEAVFEDPGVKAEMTKKVEAIIPEDCIFA 438


>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 306

 Score = 35.9 bits (79), Expect = 0.28
 Identities = 15/37 (40%), Positives = 22/37 (59%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITD 160
           K+G +G G +GR  A    + GY+V  FDVVE  + +
Sbjct: 7   KIGFIGLGAMGRPMATNLLTAGYEVHAFDVVEAAVKE 43


>UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4;
           Trichocomaceae|Rep: RIB40 genomic DNA, SC009 -
           Aspergillus oryzae
          Length = 337

 Score = 35.9 bits (79), Expect = 0.28
 Identities = 19/56 (33%), Positives = 28/56 (50%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 220
           V I+G+G+IG SW  LF + G +V + D       +    +  Q  TL + GL  G
Sbjct: 12  VAIIGTGVIGASWTALFLARGLKVLVTDPAPNAEKNLETYLNAQWPTLTQIGLSEG 67


>UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3;
           Clostridia|Rep: Dihydrolipoamide dehydrogenase -
           Clostridium tetani
          Length = 589

 Score = 35.5 bits (78), Expect = 0.37
 Identities = 13/53 (24%), Positives = 33/53 (62%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 205
           EK+ I+G G+IG  +A ++A++G +V++ +  +  ++    D+  ++  + K+
Sbjct: 295 EKIAIIGGGVIGMEFAFIYANMGVEVSVIEYFDNILSMLDEDVIKEITDIGKE 347


>UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid
           aminotransferase; 2-hydroxyacid dehydrogenase; n=2;
           Lactobacillus|Rep: Bifunctional protein: amino acid
           aminotransferase; 2-hydroxyacid dehydrogenase -
           Lactobacillus plantarum
          Length = 543

 Score = 35.5 bits (78), Expect = 0.37
 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
 Frame = +2

Query: 23  VMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVV-EKQITDAIADIKVQLKTLE 199
           + A + +S  VGI+G+G IG + A LF  +G +V  +DVV   ++ D +  +  +   L 
Sbjct: 352 LQAREIRSLTVGIIGAGRIGGTAARLFHGLGAKVIAYDVVRHPELEDVLTYVDTKEDLLR 411

Query: 200 KDGLLRGNLNADEQFQCVKGTCDLAIAVXDAIFV 301
           +  ++  +++ +E    +     L +   DA  +
Sbjct: 412 QADVVDLHVDLNETSAGLIDAAALKLMKTDAYLI 445


>UniRef50_A6M0T5 Cluster: Amine oxidase; n=6; Clostridium|Rep: Amine
           oxidase - Clostridium beijerinckii NCIMB 8052
          Length = 577

 Score = 35.5 bits (78), Expect = 0.37
 Identities = 14/35 (40%), Positives = 23/35 (65%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI 154
           KVGI+G G+ G + A     +G+ +T+F+  EK+I
Sbjct: 61  KVGIIGGGIAGLASAFELRKLGFDITIFETEEKRI 95


>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
          Length = 723

 Score = 35.5 bits (78), Expect = 0.37
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 3/117 (2%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRG 220
           K  KVGI+G+G++G   A + A  G  V L D     I  A        K L+K  + RG
Sbjct: 321 KVSKVGILGAGMMGAGIAYVSAKAGIDVVLLDT---SIEAAEKGKDYSSKLLDK-AIARG 376

Query: 221 NLNADEQFQCVKGTCDLAIA---VXDAIFVQECVPENLELKKKVFQNLDNVVDDNTI 382
             + +++ Q +    +   A   + D   + E V E++++K    +N + V+ +  I
Sbjct: 377 R-STEQKKQALLDKINTTTAYDDLEDCDLIIEAVFEDIDIKAACTRNTEAVIAETAI 432


>UniRef50_A0UYP0 Cluster: Amine oxidase; n=1; Clostridium
           cellulolyticum H10|Rep: Amine oxidase - Clostridium
           cellulolyticum H10
          Length = 572

 Score = 35.5 bits (78), Expect = 0.37
 Identities = 14/45 (31%), Positives = 25/45 (55%)
 Frame = +2

Query: 20  VVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI 154
           +    +FK + VGI+G GL G + A     +G+ +T+ +  E +I
Sbjct: 58  IARPGQFKGKSVGIIGGGLAGMAAAFELRKLGFDITILEASEDRI 102


>UniRef50_Q4J9Z6 Cluster: Conserved Crenarchaeal protein; n=3;
           Sulfolobus|Rep: Conserved Crenarchaeal protein -
           Sulfolobus acidocaldarius
          Length = 269

 Score = 35.5 bits (78), Expect = 0.37
 Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
 Frame = +2

Query: 17  RVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLF---DVVEKQITDAIADIKVQL 187
           RVV+        V IVGSG+I +S A L +++GY V +    D+ EK+     + I  Q+
Sbjct: 72  RVVIEPIEPRPGVIIVGSGMIAKSLAKLGSAMGYYVAVVGNGDLPEKEFESFTSFISNQI 131

Query: 188 KTLEK 202
           +TLE+
Sbjct: 132 ETLEQ 136


>UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 953

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 27/114 (23%), Positives = 49/114 (42%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           +   ++G+G +G    M     G    L +  ++ +   +  ++  L    K G +    
Sbjct: 327 KSAAVIGAGTMGVGITMSMVMAGIPTYLTEQNQQYLDKGLKMVQGILAHWVKQGRM-SEA 385

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
            A + F  V+ T      + D   V E V EN+ LKK++ + LD V   + IL+
Sbjct: 386 KAQQIFSLVRPTLTYD-DLKDVDVVVEAVFENMALKKEILKTLDGVCKPSAILA 438


>UniRef50_Q8YKN8 Cluster: Zeta-carotene desaturase; n=4;
           Bacteria|Rep: Zeta-carotene desaturase - Anabaena sp.
           (strain PCC 7120)
          Length = 499

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 16/35 (45%), Positives = 24/35 (68%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEK 148
           S+KV IVG+G  G + A+  A +GYQV +F+  E+
Sbjct: 2   SKKVAIVGAGPGGLATAIRLAGLGYQVEIFEAAER 36


>UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7;
           Bacteria|Rep: Dihydrolipoyl dehydrogenase - Bacteroides
           thetaiotaomicron
          Length = 447

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 17/46 (36%), Positives = 28/46 (60%)
 Frame = +2

Query: 11  TLRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEK 148
           T R  + SK     + IVG G+IG  +A  F S+G QVT+ +++++
Sbjct: 155 THRDALDSKELPASLAIVGGGVIGMEFASFFNSLGVQVTVIEMMDE 200


>UniRef50_Q6MDA0 Cluster: Probable soluble pyridine nucleotide
           transhydrogenase; n=1; Candidatus Protochlamydia
           amoebophila UWE25|Rep: Probable soluble pyridine
           nucleotide transhydrogenase - Protochlamydia amoebophila
           (strain UWE25)
          Length = 465

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 16/49 (32%), Positives = 29/49 (59%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 205
           ++G G+IG  +A  FA++G +VT+ D  +  +    A+I + L+T   D
Sbjct: 181 VLGGGIIGSEYASFFAALGTEVTVIDRKDHMLPLLDAEIGIHLQTALTD 229


>UniRef50_Q6FF29 Cluster: Putative oxidoreductase; putative
           flavoprotein monooxygenase; n=2; Acinetobacter|Rep:
           Putative oxidoreductase; putative flavoprotein
           monooxygenase - Acinetobacter sp. (strain ADP1)
          Length = 436

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQ---LKTLEKDGL 211
           K  K+ I+G+G  G + A+LFA    QVTLF+  E Q+    A + +Q   L   E  G+
Sbjct: 16  KINKIAIIGAGTAGLATAILFARQEIQVTLFEKAE-QLQPVGAGLLLQPAGLAVFEHLGI 74

Query: 212 LRGNL 226
           L   L
Sbjct: 75  LENTL 79


>UniRef50_Q6A6B6 Cluster: Pyridine nucleotide-disulphide
           oxidoreductase; n=3; Bacteria|Rep: Pyridine
           nucleotide-disulphide oxidoreductase - Propionibacterium
           acnes
          Length = 468

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKT-LEKDGL 211
           IVG G IG  +A +FA  G QVTL +  E  +     DI  +++  LE +G+
Sbjct: 185 IVGGGFIGLEFAQMFARFGSQVTLLEAGETFVPALDTDIAERVRNMLEGEGV 236


>UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
           complex dihydrolipoamide dehydrogenase E3 component;
           n=2; Proteobacteria|Rep: Pyruvate/2-oxoglutarate
           dehydrogenase complex dihydrolipoamide dehydrogenase E3
           component - Thiobacillus denitrificans (strain ATCC
           25259)
          Length = 998

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADI-KVQLKTLEKD 205
           +K+GIVG G+IG   A +F   G +V + +  ++ + +   +I KV + +LEK+
Sbjct: 706 KKLGIVGGGVIGVEMAQIFRDFGTEVLMLERHDRILAEIEEEIGKVLIASLEKE 759


>UniRef50_Q8GP50 Cluster: Eps11H; n=13; Lactobacillales|Rep: Eps11H
           - Streptococcus thermophilus
          Length = 416

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 29/104 (27%), Positives = 51/104 (49%)
 Frame = +2

Query: 35  KFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLL 214
           +FK  K+ + G+G +G S A L  S  ++VT  D++ +++     ++    K+  +D  +
Sbjct: 3   EFKDLKIAVAGTGYVGLSIATLL-SQHHKVTAVDIIPEKV-----ELINNKKSPIQDEYI 56

Query: 215 RGNLNADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVF 346
              L A+++   +  T D   A  DA FV    P N + KK  F
Sbjct: 57  EKYL-AEKELD-LTATLDAKEAYSDADFVVIAAPTNYDSKKNFF 98


>UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;
           n=7; Clostridium|Rep: (R)-2-hydroxyisocaproate
           dehydrogenase - Clostridium difficile
          Length = 331

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 19/61 (31%), Positives = 32/61 (52%)
 Frame = +2

Query: 23  VMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEK 202
           ++ ++ +S  VG++G+G IG + A LF  +G  V  FD       + I   K  L+ L K
Sbjct: 139 LLGTEVRSITVGVIGTGKIGATSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLK 198

Query: 203 D 205
           +
Sbjct: 199 E 199


>UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex, E3
           component, dihydrolipoamide dehydrogenase; n=3;
           Lactobacillus|Rep: Acetoin/pyruvate dehydrogenase
           complex, E3 component, dihydrolipoamide dehydrogenase -
           Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
          Length = 443

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 22/70 (31%), Positives = 35/70 (50%)
 Frame = +2

Query: 26  MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 205
           M  K   E + I+G+G IG  +A +FA  G +VT+ D   + ++    DI   +K   +D
Sbjct: 153 MDEKKMPENLTIIGAGYIGLEFASMFAKYGSKVTVLDHSREFLSREDDDISQLVKKDLED 212

Query: 206 GLLRGNLNAD 235
             +   L AD
Sbjct: 213 AGVHFELGAD 222


>UniRef50_A7FX66 Cluster: Pyridine nucleotide-disulphide
           oxidoreductase family protein; n=5; Clostridium|Rep:
           Pyridine nucleotide-disulphide oxidoreductase family
           protein - Clostridium botulinum (strain ATCC 19397 /
           Type A)
          Length = 438

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
 Frame = +2

Query: 14  LRVVMASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEK---QITDAIADIKVQ 184
           ++++ A +   EKV I+GSG  G + A   A  GY+VT+F+   +    +T  I + ++ 
Sbjct: 115 IKILEAVQATKEKVAIIGSGPSGLAAAAQLALEGYKVTVFEAKNQLGGWLTYGIPEDRLP 174

Query: 185 LKTLEKD-GLLRGNLNADEQFQCVKG 259
            K +E + G ++ NL    +  C  G
Sbjct: 175 QKVVENEIGYIK-NLGVHFRTNCKVG 199


>UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1;
           Acinetobacter baumannii ATCC 17978|Rep: Dihydrolipoamide
           dehydrogenase - Acinetobacter baumannii (strain ATCC
           17978 / NCDC KC 755)
          Length = 279

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
 Frame = +2

Query: 59  IVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI--TDAIADIKVQLKTLEKDGL 211
           +VGSG IG  +A L+  +G QVTL D+  KQI  T+ +   +   K  E+ G+
Sbjct: 95  VVGSGAIGSEFASLYQDLGCQVTLIDLA-KQILPTEDVEVAQFVRKQFEQKGM 146


>UniRef50_Q8TWI7 Cluster: UDP-N-acetylmuramoylalanine-D-glutamate
           ligase; n=1; Methanopyrus kandleri|Rep:
           UDP-N-acetylmuramoylalanine-D-glutamate ligase -
           Methanopyrus kandleri
          Length = 470

 Score = 35.1 bits (77), Expect = 0.49
 Identities = 28/97 (28%), Positives = 45/97 (46%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           ++V +VG+G  GRS A L   VGY V + D+  +   D   + +  L+ LE++G+     
Sbjct: 2   KRVIVVGAGSAGRSVARLLNHVGYDVVINDI--RDWEDFTTEEREYLEVLEREGVEVALG 59

Query: 227 NADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKK 337
             D +               DA FV   +PE+ E +K
Sbjct: 60  GHDREL----------FESADAAFVSPAIPEDAEGRK 86


>UniRef50_Q9X0U4 Cluster: Glutamate synthase, beta subunit; n=5;
           Bacteria|Rep: Glutamate synthase, beta subunit -
           Thermotoga maritima
          Length = 618

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEK 148
           K + VGI+GSG  G + A   A++GY VT+++   K
Sbjct: 295 KGKSVGIIGSGPAGLAAAYFLATMGYDVTIYESESK 330


>UniRef50_Q3AEV2 Cluster: Prephenate dehydrogenase; n=1;
           Carboxydothermus hydrogenoformans Z-2901|Rep: Prephenate
           dehydrogenase - Carboxydothermus hydrogenoformans
           (strain Z-2901 / DSM 6008)
          Length = 360

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 16/25 (64%), Positives = 19/25 (76%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQV 124
           K+GIVG GLIG S A  F+ +GYQV
Sbjct: 4   KIGIVGLGLIGGSLARAFSYLGYQV 28


>UniRef50_Q2RJ81 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding
           precursor; n=1; Moorella thermoacetica ATCC 39073|Rep:
           4Fe-4S ferredoxin, iron-sulfur binding precursor -
           Moorella thermoacetica (strain ATCC 39073)
          Length = 1487

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEK 148
           + EKV I+G+G  G + A   A  GYQVT++D + +
Sbjct: 255 RKEKVAIIGAGPAGLTAAQDLALAGYQVTIYDALNQ 290


>UniRef50_Q2JD10 Cluster: Prephenate dehydrogenase; n=4;
           Frankia|Rep: Prephenate dehydrogenase - Frankia sp.
           (strain CcI3)
          Length = 370

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 16/35 (45%), Positives = 24/35 (68%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI 154
           +VG+VG+GLIG S  +  ++ G +V L DV E Q+
Sbjct: 16  RVGVVGTGLIGTSIGLALSARGVEVLLRDVDEAQV 50


>UniRef50_Q1MF67 Cluster: Putative D-amino acid dehydrogenase
           precursor; n=1; Rhizobium leguminosarum bv. viciae
           3841|Rep: Putative D-amino acid dehydrogenase precursor
           - Rhizobium leguminosarum bv. viciae (strain 3841)
          Length = 403

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 19/54 (35%), Positives = 27/54 (50%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGL 211
           +V ++G+G+IG S A L A  G+ VTL D   +    A A    QL     D +
Sbjct: 3   RVAVIGAGVIGVSSAYLLARAGHDVTLIDAASEPGMGASAGNAAQLSWAYGDAM 56


>UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding; n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase, NAD-binding - Ralstonia metallidurans
           (strain CH34 / ATCC 43123 / DSM 2839)
          Length = 714

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 3/117 (2%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           ++VGI+G+G++G   A   A  G +  L DV      D     K+  + L + G+ +G +
Sbjct: 316 KRVGILGAGMMGAGIAYASAMRGIEAVLKDV----SLDHAGKGKLHSEKLLEKGVSKGKI 371

Query: 227 N---ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +    DE  Q +  T D A  +     + E V E  ELK +V +  +  + +N + +
Sbjct: 372 SPSKRDEVLQRITPTAD-ASGLAGCDIIIEAVYEKRELKAEVTREAEPHLAENGLFA 427


>UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor; n=1; Acidobacteria bacterium
           Ellin345|Rep: 3-hydroxyacyl-CoA dehydrogenase,
           NAD-binding precursor - Acidobacteria bacterium (strain
           Ellin345)
          Length = 806

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 3/117 (2%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLE--KDGLLRG 220
           EKV ++G+G +G   A  FA+ G    LFD+V     D  A  K+    L+  K      
Sbjct: 6   EKVAVLGAGTMGARIAAHFANAGIPSYLFDIVPPD-ADGPARNKIAAAGLDAAKKSKPAA 64

Query: 221 NLNAD-EQFQCVKGTCDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             + D  +   V    D    + +  ++ E V ENLELK+ + + ++ V    ++++
Sbjct: 65  FFHPDLAKLVTVGNFEDDLKKLGECDWIIEAVVENLELKRALLKKVEAVRKPGSLIT 121


>UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase
           NAD-binding; n=3; Bacteria|Rep: 3-hydroxyacyl-CoA
           dehydrogenase NAD-binding - Anaeromyxobacter sp. Fw109-5
          Length = 723

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 27/108 (25%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
 Frame = +2

Query: 44  SEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGN 223
           + +VG++G GL+G   + + A+ G  V + +  +     A+  ++  L    K   +   
Sbjct: 328 ARRVGVLGGGLMGSGISFVTANAGIPVRIRERDDAAAGKALGSVRALLDERVKRRSI-DR 386

Query: 224 LNADEQFQCVKGTCDLA-IAVXDAIFVQECVPENLELKKKVFQNLDNV 364
           L  DE+ + V  T D +  A  D +   E V E+L LK+++ +  + V
Sbjct: 387 LERDERMRLVTATTDWSGYAAVDVLI--EAVFEDLALKQEMVRAFEAV 432


>UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13;
           cellular organisms|Rep: 3-hydroxybutyryl-CoA epimerase -
           Pseudomonas putida W619
          Length = 423

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 27/123 (21%), Positives = 58/123 (47%), Gaps = 2/123 (1%)
 Frame = +2

Query: 26  MASKFKSEKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 205
           +++ +  ++  ++G+G +GR   +  A  G  V   D  +   T+A   +  Q    +  
Sbjct: 12  VSTSYNVQQTAVIGAGTMGRGIVISLARAGLPVLWLD-NDPSATEAGLAMLAQTWAQQ-- 68

Query: 206 GLLRGNLNADEQFQCVKGTCDLA--IAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNT 379
            + +G ++  +   C+     +     + +A  V E V ENL LK+++F+ LD+ +    
Sbjct: 69  -VGKGRIDQAQADACLARVRQVTAYTELAEADLVIEAVYENLALKQEIFRALDSTLKPEA 127

Query: 380 ILS 388
           IL+
Sbjct: 128 ILA 130


>UniRef50_Q4Q3S6 Cluster: Enoyl-CoA hydratase/Enoyl-CoA
           isomerase/3-hydroxyacyl-CoA dehydrogenase, putative;
           n=5; Leishmania|Rep: Enoyl-CoA hydratase/Enoyl-CoA
           isomerase/3-hydroxyacyl-CoA dehydrogenase, putative -
           Leishmania major
          Length = 934

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWA-MLFASVGYQVTLFDVVEKQITDAIADIKVQLKT-LEKDGLLRG 220
           +KV ++G+G +G S A ML      +V L +   ++   A   I+  L++ +E   L + 
Sbjct: 414 KKVAVIGAGTMGTSIALMLLRQSEIEVVLVEADTQRQEVARRSIEDYLRSRVEAHRLSQR 473

Query: 221 NLNADEQFQCVKGT--CDLAIAVXDAIFVQECVPENLELKKKVFQNLDNVVDDNTILS 388
             N       V G+        + DA  V EC PE   +K+ +   LD+V   +TIL+
Sbjct: 474 RCNDMLHRLRVMGSRIAPFPPVLADADLVFECAPEVAAIKQNILAFLDSVCKRSTILA 531


>UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7;
           Streptococcus pyogenes|Rep: D-lactate dehydrogenase -
           Streptococcus pyogenes serotype M1
          Length = 330

 Score = 34.7 bits (76), Expect = 0.64
 Identities = 16/51 (31%), Positives = 27/51 (52%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 205
           V I+G+G IG + A +F   G +V  +D+ +     A+ D K  ++   KD
Sbjct: 148 VAIIGTGRIGLATAKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKD 198


>UniRef50_Q4FKW7 Cluster: D-amino-acid dehydrogenase small chain;
           n=2; Candidatus Pelagibacter ubique|Rep: D-amino-acid
           dehydrogenase small chain - Pelagibacter ubique
          Length = 413

 Score = 34.3 bits (75), Expect = 0.85
 Identities = 15/32 (46%), Positives = 22/32 (68%)
 Frame = +2

Query: 41  KSEKVGIVGSGLIGRSWAMLFASVGYQVTLFD 136
           K+ K+GIVG+G+ G S A+     G+ VT+FD
Sbjct: 3   KNLKIGIVGAGIQGISNALFLQKKGFSVTIFD 34


>UniRef50_Q2LWM5 Cluster: Zinc-binding dehydrogenase; n=1;
           Syntrophus aciditrophicus SB|Rep: Zinc-binding
           dehydrogenase - Syntrophus aciditrophicus (strain SB)
          Length = 731

 Score = 34.3 bits (75), Expect = 0.85
 Identities = 15/39 (38%), Positives = 24/39 (61%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDA 163
           E+VG++G GLIG+    L   +GYQ   FD+ + ++  A
Sbjct: 173 ERVGVIGLGLIGQIALRLATVMGYQAYGFDISDHRVAKA 211


>UniRef50_Q1IUZ3 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
           n=1; Acidobacteria bacterium Ellin345|Rep:
           UDP-glucose/GDP-mannose dehydrogenase - Acidobacteria
           bacterium (strain Ellin345)
          Length = 422

 Score = 34.3 bits (75), Expect = 0.85
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITD-AIADIKVQLKTLEKDGLLRGNLN 229
           VG+ GSG +G   +   A +G  VT +D     + D A   ++   K L++  ++R N+ 
Sbjct: 3   VGVYGSGYLGTVVSACLADLGMPVTCYDADTTLVMDSAQGTLRFHEKNLKE--IVRRNVR 60

Query: 230 ADEQFQCVKGTCDLAIAVXDAIFVQECVPENLE 328
           AD      +   +       AIF+ E  P+ +E
Sbjct: 61  ADRLMYTTE--LESVARRAGAIFIAEDTPDEIE 91


>UniRef50_Q1IMR6 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
           n=33; Bacteria|Rep: UDP-glucose/GDP-mannose
           dehydrogenase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 448

 Score = 34.3 bits (75), Expect = 0.85
 Identities = 17/52 (32%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
 Frame = +2

Query: 5   LQTLRVVMASKFKSE--KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQI 154
           L TL   +  K ++   ++GIVG G +G   A+LF+   ++VT FD+  +++
Sbjct: 5   LGTLATELKRKIEAREARIGIVGMGYVGLPLALLFSEEKFRVTGFDIDNRKV 56


>UniRef50_Q1FMM1 Cluster: Dihydrolipoyl dehydrogenase; n=2;
           Clostridiaceae|Rep: Dihydrolipoyl dehydrogenase -
           Clostridium phytofermentans ISDg
          Length = 470

 Score = 34.3 bits (75), Expect = 0.85
 Identities = 17/52 (32%), Positives = 30/52 (57%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEK 202
           E + I+G G+IG  +A +++S G +VTL +  E+ +     +I   +K L K
Sbjct: 173 ESLLIIGGGVIGVEFATVYSSFGSKVTLLEAEERLLPGLDKEISQNIKLLLK 224


>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
           Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
           - Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 298

 Score = 34.3 bits (75), Expect = 0.85
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = +2

Query: 53  VGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTL 196
           VG++G G +GR  A    S GY V ++DV  + + + +A   V   TL
Sbjct: 6   VGVIGLGAMGRGIAQTLRSAGYAVHVYDVRAQAVQEFVAAGGVACDTL 53


>UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
           Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Rhodococcus sp. (strain RHA1)
          Length = 284

 Score = 34.3 bits (75), Expect = 0.85
 Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
 Frame = +2

Query: 47  EKVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKDGLLRGNL 226
           + VG+VG G +G   A +FA++G  V + +  +++   A+  +   L    + G L G++
Sbjct: 7   KNVGVVGGGRMGAGIAQVFATLGSTVIIAESGDREA--AVKRVSDGLDRAHERGKL-GDV 63

Query: 227 NADEQFQCVKGTCDLAIAVXDAI-FVQECVPENLELKKKVFQNLDNVVDDNTILS 388
           +       V  T     A+  A+  V E VPE ++LK  V   ++  V   T+++
Sbjct: 64  DPATILGRV-STVAAPDALPPALDLVVEAVPELVDLKLSVLSLVEKTVSPTTVIA 117


>UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 455

 Score = 34.3 bits (75), Expect = 0.85
 Identities = 15/52 (28%), Positives = 31/52 (59%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFDVVEKQITDAIADIKVQLKTLEKD 205
           ++ I+G G+IG  +A L+A++G QVT+ ++  + +     D+  + +   KD
Sbjct: 172 RLAIIGGGVIGVEFASLYATLGSQVTVIEMAPEILPFMDDDLAAKARAAMKD 223


>UniRef50_A5V9L0 Cluster: FAD dependent oxidoreductase precursor;
           n=1; Sphingomonas wittichii RW1|Rep: FAD dependent
           oxidoreductase precursor - Sphingomonas wittichii RW1
          Length = 403

 Score = 34.3 bits (75), Expect = 0.85
 Identities = 15/29 (51%), Positives = 20/29 (68%)
 Frame = +2

Query: 50  KVGIVGSGLIGRSWAMLFASVGYQVTLFD 136
           KVG+VG G+IG S A+  A  G +V LF+
Sbjct: 31  KVGVVGGGIIGASTALQLARAGAEVILFE 59


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 396,440,993
Number of Sequences: 1657284
Number of extensions: 7425067
Number of successful extensions: 27283
Number of sequences better than 10.0: 451
Number of HSP's better than 10.0 without gapping: 26471
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 27204
length of database: 575,637,011
effective HSP length: 91
effective length of database: 424,824,167
effective search space used: 16143318346
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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