Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30593
(728 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to ENSANGP000... 353 3e-96
UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue succinyltra... 334 1e-90
UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome s... 332 5e-90
UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit... 307 2e-82
UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 297 1e-79
UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;... 295 5e-79
UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue succinyltra... 285 6e-76
UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue succinyltra... 283 2e-75
UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza sativa... 282 7e-75
UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 278 9e-74
UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 277 2e-73
UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase co... 276 5e-73
UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase; ... 274 1e-72
UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue su... 272 6e-72
UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue succinyltra... 272 6e-72
UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 270 2e-71
UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue succinyltra... 270 2e-71
UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n... 269 4e-71
UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 268 9e-71
UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransfer... 267 2e-70
UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase comp... 267 2e-70
UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue succinyltra... 267 2e-70
UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase co... 266 5e-70
UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n... 265 9e-70
UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 265 9e-70
UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 265 9e-70
UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1... 264 1e-69
UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue succinyltra... 262 6e-69
UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 262 8e-69
UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 261 1e-68
UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (... 259 4e-68
UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 257 2e-67
UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide S-succinyltra... 257 2e-67
UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 252 7e-66
UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue succinyltra... 252 7e-66
UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 250 2e-65
UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1; ... 250 3e-65
UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n... 249 6e-65
UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue succinyltra... 248 8e-65
UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n... 246 3e-64
UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase co... 244 2e-63
UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase, p... 244 2e-63
UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue succinyltra... 236 5e-61
UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 231 1e-59
UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue succinyltra... 227 2e-58
UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1; ... 216 5e-55
UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 180 4e-44
UniRef50_A1SJ23 Cluster: Catalytic domain of components of vario... 165 7e-40
UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n... 165 1e-39
UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue succinyltra... 165 1e-39
UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;... 160 3e-38
UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component, d... 160 4e-38
UniRef50_P37942 Cluster: Lipoamide acyltransferase component of ... 160 4e-38
UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase co... 157 3e-37
UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 157 3e-37
UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransfera... 157 3e-37
UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2, dihy... 155 8e-37
UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2 compo... 155 1e-36
UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1; Symbiob... 154 2e-36
UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransfera... 154 2e-36
UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid dehydrog... 153 3e-36
UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue succinyltra... 153 3e-36
UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;... 153 6e-36
UniRef50_A1UIB1 Cluster: Catalytic domain of components of vario... 152 7e-36
UniRef50_A5UTW4 Cluster: Catalytic domain of components of vario... 151 2e-35
UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1; Streptom... 150 3e-35
UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n... 150 4e-35
UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC ... 149 9e-35
UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue succinyltra... 149 9e-35
UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase... 148 1e-34
UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of ... 148 1e-34
UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 147 3e-34
UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue acetyltrans... 146 4e-34
UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 146 5e-34
UniRef50_Q67RX4 Cluster: Putative uncharacterized protein; n=1; ... 146 5e-34
UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;... 146 5e-34
UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase e... 145 8e-34
UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of ... 145 1e-33
UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E... 144 1e-33
UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of ... 144 2e-33
UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue acetyltrans... 144 2e-33
UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue succinyltra... 143 5e-33
UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;... 142 6e-33
UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of ... 142 6e-33
UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue ac... 142 1e-32
UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep: ... 141 2e-32
UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;... 141 2e-32
UniRef50_Q98PG1 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 140 2e-32
UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid dehydrog... 140 2e-32
UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic doma... 140 2e-32
UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue acetyltrans... 140 2e-32
UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex, dihydro... 140 3e-32
UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase comp... 140 4e-32
UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase comp... 139 6e-32
UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1; Bdellov... 138 1e-31
UniRef50_A6TMP1 Cluster: Catalytic domain of components of vario... 138 1e-31
UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC - Clos... 138 1e-31
UniRef50_P09062 Cluster: Lipoamide acyltransferase component of ... 138 1e-31
UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3; Cystoba... 137 2e-31
UniRef50_Q1AZ52 Cluster: Catalytic domain of components of vario... 137 2e-31
UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase, c... 137 2e-31
UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacte... 136 5e-31
UniRef50_Q1AT73 Cluster: Catalytic domain of components of vario... 136 5e-31
UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=... 136 7e-31
UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1... 136 7e-31
UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue succinyltra... 136 7e-31
UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n... 135 1e-30
UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransfera... 134 2e-30
UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 134 2e-30
UniRef50_A0LLM2 Cluster: Catalytic domain of components of vario... 134 3e-30
UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue acetyltrans... 134 3e-30
UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3... 133 4e-30
UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 133 4e-30
UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, ... 133 4e-30
UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 133 4e-30
UniRef50_Q14Q97 Cluster: Putative uncharacterized protein; n=1; ... 133 5e-30
UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex dihydrol... 132 6e-30
UniRef50_A0JUQ7 Cluster: Catalytic domain of components of vario... 132 6e-30
UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue acetyltrans... 132 8e-30
UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 131 1e-29
UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of ... 131 1e-29
UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3; ... 131 2e-29
UniRef50_A4WK39 Cluster: Catalytic domain of components of vario... 131 2e-29
UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4; Bacilla... 130 3e-29
UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1... 130 3e-29
UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2 com... 130 3e-29
UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase co... 130 3e-29
UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase comp... 130 3e-29
UniRef50_A1SQB9 Cluster: Catalytic domain of components of vario... 130 3e-29
UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1; Pyrobac... 130 5e-29
UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex,... 129 6e-29
UniRef50_A4XEQ9 Cluster: Catalytic domain of components of vario... 129 6e-29
UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 129 8e-29
UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase comp... 129 8e-29
UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase co... 128 1e-28
UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue acetyltrans... 128 1e-28
UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4; Actinomycet... 128 1e-28
UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue acetyltrans... 128 1e-28
UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component, d... 128 2e-28
UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia gloss... 128 2e-28
UniRef50_A0LSF1 Cluster: Catalytic domain of components of vario... 128 2e-28
UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7... 127 2e-28
UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2... 127 2e-28
UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of p... 126 4e-28
UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue acetyltrans... 126 4e-28
UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase comp... 126 6e-28
UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component dih... 126 6e-28
UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue acetyltrans... 126 6e-28
UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferas... 125 1e-27
UniRef50_A5V4B2 Cluster: Catalytic domain of components of vario... 125 1e-27
UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex dihydrol... 125 1e-27
UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component, dih... 125 1e-27
UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2 comp... 125 1e-27
UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2 com... 125 1e-27
UniRef50_Q15U82 Cluster: Catalytic domain of components of vario... 124 2e-27
UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic doma... 124 2e-27
UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue succinyltra... 124 2e-27
UniRef50_A7HHV9 Cluster: Pyruvate dehydrogenase complex dihydrol... 124 2e-27
UniRef50_A0LQU7 Cluster: Catalytic domain of components of vario... 124 2e-27
UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate d... 124 3e-27
UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,... 124 3e-27
UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2 comp... 124 3e-27
UniRef50_A6W003 Cluster: Catalytic domain of components of vario... 124 3e-27
UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue acetyltrans... 124 3e-27
UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 124 3e-27
UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 124 3e-27
UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=4... 123 4e-27
UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2 comp... 123 5e-27
UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;... 123 5e-27
UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue succinyltra... 122 9e-27
UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n... 122 1e-26
UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1; ... 122 1e-26
UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2... 122 1e-26
UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of ... 121 2e-26
UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue acetyltrans... 120 3e-26
UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue acetyltrans... 120 3e-26
UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid... 120 5e-26
UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 120 5e-26
UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, who... 119 6e-26
UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep... 119 8e-26
UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1; ... 119 8e-26
UniRef50_A0K281 Cluster: Catalytic domain of components of vario... 118 1e-25
UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue acetyltrans... 118 1e-25
UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 118 1e-25
UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, lon... 118 1e-25
UniRef50_Q057U1 Cluster: Pyruvate dehydrogenase E2 component; n=... 118 1e-25
UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=... 118 1e-25
UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue acetyltrans... 118 1e-25
UniRef50_A4SZ52 Cluster: Catalytic domain of components of vario... 118 2e-25
UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain transac... 118 2e-25
UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue acetyltrans... 118 2e-25
UniRef50_Q1GTH9 Cluster: Catalytic domain of components of vario... 117 3e-25
UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue acetyltrans... 117 3e-25
UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;... 117 3e-25
UniRef50_A1SQ65 Cluster: Catalytic domain of components of vario... 117 3e-25
UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain transac... 117 3e-25
UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 116 4e-25
UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase c... 116 4e-25
UniRef50_A4XHV3 Cluster: Catalytic domain of components of vario... 116 4e-25
UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue acetyltrans... 116 4e-25
UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1; ... 116 6e-25
UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue acetyltrans... 116 6e-25
UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E... 116 8e-25
UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate d... 115 1e-24
UniRef50_A0JZU9 Cluster: Catalytic domain of components of vario... 115 1e-24
UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue succinyltra... 115 1e-24
UniRef50_Q1V1J3 Cluster: Dihydrolipoamide S-acetyltransferase; n... 114 2e-24
UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex dihydrol... 114 2e-24
UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide ... 114 2e-24
UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3 compo... 114 2e-24
UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular organi... 114 2e-24
UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases acyl... 113 3e-24
UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2... 113 3e-24
UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2; ... 113 3e-24
UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2 comp... 113 4e-24
UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2 compo... 113 4e-24
UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme comp... 113 6e-24
UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase homo... 112 7e-24
UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1... 112 7e-24
UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2; Actinom... 112 7e-24
UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 / dihydrolipo... 112 7e-24
UniRef50_P11182 Cluster: Lipoamide acyltransferase component of ... 112 7e-24
UniRef50_A6PJ30 Cluster: Catalytic domain of components of vario... 112 1e-23
UniRef50_A1KCD0 Cluster: Putative uncharacterized protein; n=1; ... 112 1e-23
UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1; Dictyo... 111 1e-23
UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex d... 111 2e-23
UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep: M... 111 2e-23
UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;... 111 2e-23
UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA ... 111 2e-23
UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 111 2e-23
UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase comp... 111 2e-23
UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue acetyltrans... 111 2e-23
UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X compon... 110 4e-23
UniRef50_A0NRH8 Cluster: Branched-chain alpha-keto acid dehydrog... 109 7e-23
UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 109 7e-23
UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding pro... 107 2e-22
UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.... 107 3e-22
UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic doma... 107 3e-22
UniRef50_A3SYT7 Cluster: Acetoin dehydrogenase E2 component; n=2... 107 3e-22
UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;... 107 3e-22
UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2 compo... 107 4e-22
UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila melanog... 107 4e-22
UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue acetyltrans... 107 4e-22
UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue acetyltrans... 106 5e-22
UniRef50_UPI000038D51F Cluster: COG0508: Pyruvate/2-oxoglutarate... 105 8e-22
UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 105 8e-22
UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella ve... 105 8e-22
UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component, di... 105 1e-21
UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2... 105 1e-21
UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 105 1e-21
UniRef50_Q89AQ9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 105 1e-21
UniRef50_A1RJV4 Cluster: Catalytic domain of components of vario... 104 2e-21
UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Eugl... 104 2e-21
UniRef50_A4S3G1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 104 2e-21
UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransfera... 104 2e-21
UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n... 104 3e-21
UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;... 104 3e-21
UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid dehydrog... 103 3e-21
UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; ... 103 3e-21
UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2) c... 103 4e-21
UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransfera... 103 6e-21
UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9; Eur... 103 6e-21
UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 99 1e-19
UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1; ... 96 7e-19
UniRef50_Q8D6Q5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 94 4e-18
UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase, put... 94 4e-18
UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide ... 92 1e-17
UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3... 92 1e-17
UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of ... 92 1e-17
UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).; ... 91 3e-17
UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, wh... 90 4e-17
UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole gen... 89 8e-17
UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8; Plas... 89 8e-17
UniRef50_A0G738 Cluster: Catalytic domain of components of vario... 89 1e-16
UniRef50_Q7SH25 Cluster: Putative uncharacterized protein NCU027... 89 1e-16
UniRef50_A6PBA2 Cluster: Catalytic domain of components of vario... 88 2e-16
UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2; ... 88 2e-16
UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16
UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2; ... 87 3e-16
UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2 comp... 87 4e-16
UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoam... 87 5e-16
UniRef50_Q5DAR0 Cluster: SJCHGC04873 protein; n=1; Schistosoma j... 87 5e-16
UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 86 7e-16
UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2 com... 86 1e-15
UniRef50_Q0A5F2 Cluster: Catalytic domain of components of vario... 85 1e-15
UniRef50_Q55AS9 Cluster: Pyruvate dehydrogenase complex, compone... 85 2e-15
UniRef50_Q7VDH5 Cluster: Dihydrolipoamide S-acetyltransferase; n... 84 3e-15
UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 84 4e-15
UniRef50_A4BTC4 Cluster: Dihydrolipoamide acetyltransferase; n=2... 83 5e-15
UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 83 9e-15
UniRef50_Q83DQ8 Cluster: Dehydrogenase, E2 component, acyltransf... 82 2e-14
UniRef50_A0JS87 Cluster: Catalytic domain of components of vario... 81 2e-14
UniRef50_Q7NHG8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 81 3e-14
UniRef50_Q6XYS6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 80 5e-14
UniRef50_Q5ZV80 Cluster: Dihydrolipoamide acetyltransferase; n=5... 79 8e-14
UniRef50_Q12FH2 Cluster: Catalytic domain of components of vario... 79 1e-13
UniRef50_A0J2S5 Cluster: Catalytic domain of components of vario... 79 1e-13
UniRef50_A1UBW5 Cluster: Catalytic domain of components of vario... 77 3e-13
UniRef50_A1FTV4 Cluster: Catalytic domain of components of vario... 77 4e-13
UniRef50_Q8PQ85 Cluster: Dihydrolipoamide acyltransferase; n=7; ... 77 6e-13
UniRef50_Q9K3H2 Cluster: Putative acyltransferase; n=1; Streptom... 73 1e-11
UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacyla... 71 2e-11
UniRef50_Q7MB23 Cluster: Similar to peptide synthetase. Putative... 71 2e-11
UniRef50_A5V538 Cluster: Catalytic domain of components of vario... 71 4e-11
UniRef50_A6FIQ1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 70 5e-11
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 70 7e-11
UniRef50_A6Q3I4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 68 3e-10
UniRef50_A0Z5N6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 66 8e-10
UniRef50_A2WKX8 Cluster: Putative uncharacterized protein; n=1; ... 66 8e-10
UniRef50_Q7RFX9 Cluster: Putative dihydrolipoamide S-acetyltrans... 64 3e-09
UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex su... 64 3e-09
UniRef50_Q5VGY2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 64 3e-09
UniRef50_A3CFJ5 Cluster: Putative uncharacterized protein; n=2; ... 63 6e-09
UniRef50_Q4P9L5 Cluster: Putative uncharacterized protein; n=1; ... 63 6e-09
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 61 2e-08
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 61 3e-08
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 61 3e-08
UniRef50_A6Q9K5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 60 4e-08
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ... 57 5e-07
UniRef50_Q9KBS7 Cluster: BH1847 protein; n=1; Bacillus haloduran... 55 2e-06
UniRef50_Q4E6V7 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_Q7TQ85 Cluster: Ac1164; n=1; Rattus norvegicus|Rep: Ac1... 47 5e-04
UniRef50_Q7NLM9 Cluster: Gll1092 protein; n=1; Gloeobacter viola... 46 0.001
UniRef50_Q5BY55 Cluster: SJCHGC04170 protein; n=1; Schistosoma j... 45 0.002
UniRef50_A4F1Y4 Cluster: Dihydrolopoamide acyltransferase; n=1; ... 44 0.003
UniRef50_Q3W1D8 Cluster: Catalytic domain of components of vario... 44 0.005
UniRef50_UPI00006CB607 Cluster: hypothetical protein TTHERM_0044... 42 0.012
UniRef50_Q9SIT8 Cluster: Putative uncharacterized protein At2g13... 42 0.012
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 42 0.015
UniRef50_A6TN70 Cluster: Catalytic domain of components of vario... 42 0.020
UniRef50_A3TFL4 Cluster: Putative uncharacterized protein; n=1; ... 41 0.027
UniRef50_A5CEC1 Cluster: Putative uncharacterized protein; n=6; ... 41 0.036
UniRef50_Q1QQR8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.062
UniRef50_UPI000038CE95 Cluster: COG0508: Pyruvate/2-oxoglutarate... 39 0.14
UniRef50_Q8G5G2 Cluster: Putative uncharacterized protein; n=5; ... 39 0.14
UniRef50_O61646 Cluster: Splicing factor SRp54; n=8; Endopterygo... 39 0.14
UniRef50_Q61FS8 Cluster: Putative uncharacterized protein CBG115... 38 0.19
UniRef50_Q1D6S2 Cluster: 2-oxo acid dehydrogenase acyltransferas... 38 0.25
UniRef50_A7MGN4 Cluster: Putative uncharacterized protein; n=2; ... 38 0.25
UniRef50_A0GGU8 Cluster: Putative uncharacterized protein; n=1; ... 38 0.33
UniRef50_Q3ADI4 Cluster: Putative uncharacterized protein; n=1; ... 37 0.44
UniRef50_Q2CHG7 Cluster: Parallel beta-helix repeat protein; n=4... 36 0.77
UniRef50_Q08S44 Cluster: Putative uncharacterized protein; n=1; ... 36 0.77
UniRef50_UPI0001555271 Cluster: PREDICTED: similar to golgi auto... 36 1.0
UniRef50_A5K369 Cluster: U2 snRNP auxiliary factor, putative; n=... 36 1.0
UniRef50_A0H191 Cluster: E3 binding; n=1; Chloroflexus aggregans... 36 1.3
UniRef50_Q7RHM7 Cluster: Cyclophilin-RNA interacting protein; n=... 36 1.3
UniRef50_P09269 Cluster: Transcriptional transactivator IE4; n=3... 36 1.3
UniRef50_Q3LVF5 Cluster: TO119-1rc; n=1; Taraxacum officinale|Re... 35 1.8
UniRef50_Q55BA4 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_Q8ZV49 Cluster: Arsenite transport protein, conjectural... 35 1.8
UniRef50_Q2NXC9 Cluster: Putative uncharacterized protein XOO429... 35 2.3
UniRef50_A0C618 Cluster: Chromosome undetermined scaffold_151, w... 35 2.3
UniRef50_P30189 Cluster: DNA topoisomerase 1; n=7; Endopterygota... 35 2.3
UniRef50_A4AFV6 Cluster: ATP-dependent RNA helicase; n=3; Actino... 34 3.1
UniRef50_Q69K05 Cluster: CAX-interacting protein 4 (CAXIP4)-like... 34 3.1
UniRef50_A4R9H3 Cluster: Predicted protein; n=1; Magnaporthe gri... 34 3.1
UniRef50_Q86YZ3 Cluster: Hornerin; n=8; Theria|Rep: Hornerin - H... 34 3.1
UniRef50_Q3JRC8 Cluster: Putative uncharacterized protein; n=5; ... 34 4.1
UniRef50_A3DKD8 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1
UniRef50_A6R9N6 Cluster: Predicted protein; n=24; Ajellomyces ca... 34 4.1
UniRef50_A6R5U3 Cluster: Predicted protein; n=10; Ajellomyces ca... 34 4.1
UniRef50_UPI0000DB78AB Cluster: PREDICTED: hypothetical protein;... 33 5.4
UniRef50_Q5RI63 Cluster: Novel protein; n=13; Danio rerio|Rep: N... 33 5.4
UniRef50_Q1D4C4 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4
UniRef50_A6FUH5 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4
UniRef50_Q4CZM2 Cluster: Putative uncharacterized protein; n=3; ... 33 5.4
UniRef50_UPI00015BCEF9 Cluster: UPI00015BCEF9 related cluster; n... 33 7.2
UniRef50_Q5PBL0 Cluster: NADH dehydrogenase I chain L; n=5; Anap... 33 7.2
UniRef50_A7BMP4 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_A3MEK5 Cluster: 2,4-dihydroxyhept-2-ene-1,7-dioic acid ... 33 7.2
UniRef50_A0UED9 Cluster: 200 kDa antigen p200, putative; n=2; Bu... 33 7.2
UniRef50_A7S2A3 Cluster: Predicted protein; n=1; Nematostella ve... 33 7.2
UniRef50_A6SI95 Cluster: Predicted protein; n=1; Botryotinia fuc... 33 7.2
UniRef50_Q12A39 Cluster: Surface antigen (D15) precursor; n=7; B... 33 9.5
UniRef50_A4RTA5 Cluster: Predicted protein; n=1; Ostreococcus lu... 33 9.5
UniRef50_Q7S5P5 Cluster: Predicted protein; n=1; Neurospora cras... 33 9.5
UniRef50_A4R4W3 Cluster: Putative uncharacterized protein; n=3; ... 33 9.5
UniRef50_A3LT76 Cluster: Phosphatidylinositol kinase; n=1; Pichi... 33 9.5
UniRef50_Q9YA80 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
UniRef50_Q9HWX4 Cluster: Riboflavin biosynthesis protein ribAB [... 33 9.5
UniRef50_P40376 Cluster: cAMP-dependent protein kinase catalytic... 33 9.5
UniRef50_Q27450 Cluster: Peptidyl-prolyl cis-trans isomerase 1; ... 33 9.5
>UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to
ENSANGP00000010144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010144 - Nasonia
vitripennis
Length = 483
Score = 353 bits (868), Expect = 3e-96
Identities = 163/218 (74%), Positives = 196/218 (89%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RLKDAQNTNAMLTTFNEIDMS ++ FRK + ++F KK+ +KLG MSPF+ A+A AL
Sbjct: 266 IAERLKDAQNTNAMLTTFNEIDMSALIDFRKSNQESFQKKYGLKLGFMSPFIAASAYALK 325
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
DQPVVNAVI+ +I+YRDYVDISVAVATPKGLVVPV+R+V+N +A+IE+ +A + +KAR
Sbjct: 326 DQPVVNAVIDGTDIVYRDYVDISVAVATPKGLVVPVLRSVENKNFAEIEIAMAAVGDKAR 385
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GK+++E+MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHG+F+RPIA+ GQVVIRPM
Sbjct: 386 KGKISVEDMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGVFDRPIAVKGQVVIRPM 445
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MY+ALTYDHRLIDGREAV+FLRKIK+ VEDP I+AGL
Sbjct: 446 MYVALTYDHRLIDGREAVMFLRKIKDAVEDPRIILAGL 483
>UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=48;
Fungi/Metazoa group|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor - Homo
sapiens (Human)
Length = 453
Score = 334 bits (821), Expect = 1e-90
Identities = 160/220 (72%), Positives = 186/220 (84%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQRLK+AQNT AMLTTFNEIDMS+I R +H + F KKH++KLG MS FVKA+A AL
Sbjct: 234 IAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQ 293
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+QPVVNAVI++ E++YRDY+DISVAVATP+GLVVPVIRNV+ M +ADIE TI L EK
Sbjct: 294 EQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEK 353
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR +L IE+MDGGTFTISNGGVFGSL GTPIINPPQSAILGMHGIF+RP+A+ G+V +R
Sbjct: 354 ARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVR 413
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
PMMY+ALTYDHRLIDGREAV FLRKIK VEDP ++ L
Sbjct: 414 PMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL 453
>UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=5; Bilateria|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 461
Score = 332 bits (816), Expect = 5e-90
Identities = 162/217 (74%), Positives = 182/217 (83%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQRLK+AQNT AMLTTFNE+DMS+I RK + D F KKH+IKLG MS FVKAAA AL
Sbjct: 242 IAQRLKEAQNTCAMLTTFNEVDMSNISEMRKTYKDAFLKKHNIKLGFMSAFVKAAAYALA 301
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
DQP VN VI++ EI+YRDYVDISVAVATPKGLVVPVIRNV+ M +ADIE I L EK
Sbjct: 302 DQPAVNGVIDDTTKEIVYRDYVDISVAVATPKGLVVPVIRNVEGMNFADIEKAINLLGEK 361
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR +L +E+MDGGTFTISNGGVFGS+ GTPIINPPQSAILGMHGIFERP+A+ G+V IR
Sbjct: 362 ARKNELAVEDMDGGTFTISNGGVFGSMFGTPIINPPQSAILGMHGIFERPVAIGGKVEIR 421
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
PMMY+ALTYDHRLIDGREAV FLRKIK VEDP ++
Sbjct: 422 PMMYVALTYDHRLIDGREAVTFLRKIKSVVEDPRVLL 458
>UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit;
n=15; Magnoliophyta|Rep: 2-oxoglutarate dehydrogenase E2
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 464
Score = 307 bits (753), Expect = 2e-82
Identities = 143/215 (66%), Positives = 178/215 (82%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A RLKD+QNT A+LTTFNE+DM+++M R ++ D F +KH +KLGLMS F+KAA +AL
Sbjct: 247 VATRLKDSQNTFALLTTFNEVDMTNLMKLRSQYKDAFLEKHGVKLGLMSGFIKAAVSALQ 306
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
QPVVNAVI+ ++IIYRDYVDIS+AV T KGLVVPVIR+ M +ADIE TI GLA+KA
Sbjct: 307 HQPVVNAVIDGDDIIYRDYVDISIAVGTSKGLVVPVIRDADKMNFADIEKTINGLAKKAT 366
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G ++I+EM GG+FT+SNGGV+GSL+ TPIINPPQSAILGMH I +RP+ + G VV RPM
Sbjct: 367 EGTISIDEMAGGSFTVSNGGVYGSLISTPIINPPQSAILGMHSIVQRPMVVGGSVVPRPM 426
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+ALTYDHRLIDGREAV FLR+IK+ VEDP ++
Sbjct: 427 MYVALTYDHRLIDGREAVYFLRRIKDVVEDPQRLL 461
>UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase family protein -
Tetrahymena thermophila SB210
Length = 564
Score = 297 bits (730), Expect = 1e-79
Identities = 137/215 (63%), Positives = 171/215 (79%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I QRLKD+QNT A+L TFNE+DMS++M R K+ + F KKH++KLG MS FVKAA AL
Sbjct: 347 IGQRLKDSQNTYALLPTFNEVDMSNVMEIRNKYQEQFQKKHNVKLGFMSFFVKAATAALQ 406
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
QP+VNAVI+ EI+YR+YVDISVAVATP GL+VPV+RN +NM++AD+E I L K +
Sbjct: 407 QQPIVNAVIDGKEIVYRNYVDISVAVATPTGLMVPVLRNTENMSFADVEREIIRLGNKGK 466
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G +T+E+M GGTFTISNGG +GSL G PI+NPPQSAILGMH + RP+ Q+V RPM
Sbjct: 467 EGSITVEDMVGGTFTISNGGTYGSLFGMPILNPPQSAILGMHAVQNRPVVRGDQIVARPM 526
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+ALTYDHRLIDGREAV FL+ IKE VE+P+ ++
Sbjct: 527 MYLALTYDHRLIDGREAVTFLKTIKEIVEEPSKLL 561
>UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Dictyostelium discoideum|Rep: Dihydrolipoamide
S-succinyltransferase - Dictyostelium discoideum AX4
Length = 439
Score = 295 bits (725), Expect = 5e-79
Identities = 140/217 (64%), Positives = 174/217 (80%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
AQRLKD+QNT AMLTTFNE+DMS +M RK + D F KKH +K G MS FVKA+ AL +
Sbjct: 223 AQRLKDSQNTAAMLTTFNELDMSALMNMRKTYKDEFEKKHGVKFGFMSAFVKASTIALKE 282
Query: 185 QPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKART 364
QP+VNA +EEN+I+Y + V+I+VAV+ P+GLVVPVIRN +N+++ADIE I L+ AR
Sbjct: 283 QPIVNASVEENDIVYHNNVNINVAVSAPRGLVVPVIRNCENLSFADIEKEIGRLSGLARN 342
Query: 365 GKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMM 544
L IE+ GGTFTISNGGVFGS+ GTPIINPPQSAILGMH I +RP +NGQVV+RP+M
Sbjct: 343 DALAIEDSIGGTFTISNGGVFGSMFGTPIINPPQSAILGMHAIKDRPYVVNGQVVVRPIM 402
Query: 545 YIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
Y+ALTYDHR+IDGREAV FL+KIK+ +E+P I+ L
Sbjct: 403 YLALTYDHRIIDGREAVTFLKKIKDVLENPERILLEL 439
>UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=21;
Ascomycota|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 463
Score = 285 bits (700), Expect = 6e-76
Identities = 134/211 (63%), Positives = 163/211 (77%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RLK++QNT A LTTFNE+DMS +M RK + D KK K G M F KA A
Sbjct: 247 IAERLKESQNTAASLTTFNEVDMSALMEMRKLYKDEIIKKTGTKFGFMGLFSKACTLAAK 306
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
D P VN IE ++I+YRDY DISVAVATPKGLV PV+RN ++++ DIE I L+ KAR
Sbjct: 307 DIPAVNGAIEGDQIVYRDYTDISVAVATPKGLVTPVVRNAESLSVLDIENEIVRLSHKAR 366
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKLT+E+M GGTFTISNGGVFGSL GTPIIN PQ+A+LG+HG+ ERP+ +NGQ+V RPM
Sbjct: 367 DGKLTLEDMTGGTFTISNGGVFGSLYGTPIINSPQTAVLGLHGVKERPVTVNGQIVSRPM 426
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
MY+ALTYDHRL+DGREAV FL+ +KE +EDP
Sbjct: 427 MYLALTYDHRLLDGREAVTFLKTVKELIEDP 457
>UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial; n=8; Dikarya|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex,
mitochondrial - Coccidioides immitis
Length = 484
Score = 283 bits (695), Expect = 2e-75
Identities = 140/221 (63%), Positives = 168/221 (76%), Gaps = 4/221 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RLK +QNT A LTTFNE+DMS +M FRK + + KK IKLG MS F +A A+
Sbjct: 264 IAERLKQSQNTAASLTTFNEVDMSSLMEFRKLYKEDILKKTGIKLGFMSAFARACVLAMK 323
Query: 182 DQPVVNAVIEE----NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLA 349
+ P VNA IE + I+YRDYVDISVAVAT KGLV PV+RNV+NM IE IA L
Sbjct: 324 EVPAVNASIEGPNGGDTIVYRDYVDISVAVATEKGLVTPVVRNVENMDLTTIEKAIADLG 383
Query: 350 EKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVV 529
+KAR KLTIE+M GGTFTISNGGVFGSLMGTPIIN PQ+ +LG+H I RP+A+NG+V
Sbjct: 384 QKARDNKLTIEDMAGGTFTISNGGVFGSLMGTPIINLPQTGVLGLHAIKNRPVAVNGKVE 443
Query: 530 IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAG 652
IRPMMY+ALTYDHRL+DGREAV FL ++KE +EDP ++ G
Sbjct: 444 IRPMMYLALTYDHRLLDGREAVTFLVRVKEFIEDPRRMLLG 484
>UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza
sativa|Rep: Os02g0514700 protein - Oryza sativa subsp.
japonica (Rice)
Length = 497
Score = 282 bits (691), Expect = 7e-75
Identities = 136/215 (63%), Positives = 169/215 (78%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RLKD+QNT AML TFNE+DM+++M + D F +KH +KLGLMS FVKAA +AL
Sbjct: 280 IANRLKDSQNTFAMLITFNEVDMTNLMKLLSDYKDQFVEKHGVKLGLMSCFVKAAVSALQ 339
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+QP+VNAVI+ ++IIYR+Y+DISVAV T KGLVV VI ++ M +ADIE I LA+KA
Sbjct: 340 NQPIVNAVIDGDDIIYREYIDISVAVGTSKGLVVLVIHDIDAMNFADIEKGINNLAKKAT 399
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G +I M GGTFTISNGGV+GSL+ TPIIN PQS+ILGMH I +R + +NG V+ RPM
Sbjct: 400 EGAQSINNMAGGTFTISNGGVYGSLISTPIINSPQSSILGMHSIVQRLVVVNGSVLARPM 459
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+AL YDHRLIDGREAVLFLR+IK+ VEDP ++
Sbjct: 460 MYLALMYDHRLIDGREAVLFLRRIKDVVEDPRRLL 494
>UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase,
putative; n=5; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase, putative - Leishmania major
Length = 389
Score = 278 bits (682), Expect = 9e-74
Identities = 137/218 (62%), Positives = 167/218 (76%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RLK +QNT AMLTTFNEIDM+ + R K+ D F K+H +KLGLMSPFVKA+A AL
Sbjct: 171 IADRLKASQNTCAMLTTFNEIDMTPLFQLRDKYKDEFHKRHDVKLGLMSPFVKASAIALK 230
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
D P+VNA ++ I Y ++VDI++AVATP+GLVVPVIR+VQNM A+IE IA A +AR
Sbjct: 231 DVPIVNASFGKDTIDYHEFVDIAIAVATPRGLVVPVIRDVQNMNLANIETAIADYAARAR 290
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KLT+ EM GGTFTISNGGVFGS MGTPIINPP SAILGMH I ++P + ++ IR +
Sbjct: 291 INKLTMAEMTGGTFTISNGGVFGSWMGTPIINPPHSAILGMHAIKKKPWVVGNEIKIRDI 350
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
M +ALTYDHRLIDG +AV FL K+K +EDPA +V L
Sbjct: 351 MAVALTYDHRLIDGSDAVTFLVKVKNLIEDPARMVLDL 388
>UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Orientia tsutsugamushi (strain
Boryong) (Rickettsia tsutsugamushi)
Length = 425
Score = 277 bits (679), Expect = 2e-73
Identities = 125/218 (57%), Positives = 170/218 (77%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQRLKD+QN A+L+TFNE+DM ++ RKK+ + F KKH IKLG MS FVKAA AL
Sbjct: 208 IAQRLKDSQNNAAILSTFNEVDMFNVSELRKKYKEEFEKKHEIKLGFMSFFVKAATAALQ 267
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P++NA ++ +I+Y +Y DI VAV+T GLVVP+IRN +++++A+IE+ I+ L +KAR
Sbjct: 268 ELPIINAQVDGYDILYHNYCDIGVAVSTNSGLVVPIIRNAEHLSFAEIEMEISQLGKKAR 327
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G L+I E+ GGTF+I+NGGVFGSL+ TPIINPPQSAI+GMH I +RP+ +NG + IRPM
Sbjct: 328 EGNLSINELSGGTFSITNGGVFGSLLSTPIINPPQSAIMGMHKIQDRPVVINGTIQIRPM 387
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MYI L+YDHR+IDG+EAV FL K+K +E P ++ +
Sbjct: 388 MYIVLSYDHRIIDGKEAVTFLTKVKSYIESPERLLLNI 425
>UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=42;
Proteobacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 425
Score = 276 bits (676), Expect = 5e-73
Identities = 128/218 (58%), Positives = 169/218 (77%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL ++Q TNA+LTTFNE++M +M R K+ D F K+H +KLG MS FVKAA +AL
Sbjct: 208 IAERLLESQQTNAILTTFNEVNMQPVMDLRAKYKDKFEKEHGVKLGFMSFFVKAAVHALK 267
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P+VNA I+ N+I+Y Y DI +AV +P+GLVVP++RN ++ A+IE IA +KA+
Sbjct: 268 KFPLVNASIDGNDIVYHGYFDIGIAVGSPRGLVVPILRNADQLSLAEIEKKIAEFGQKAK 327
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKL+IEEM GGTF+ISNGGVFGS++ TPIINPPQSAILG+H ERP+ NGQ+VIRP+
Sbjct: 328 DGKLSIEEMTGGTFSISNGGVFGSMLSTPIINPPQSAILGVHATKERPVVENGQIVIRPI 387
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
Y+AL+YDHR+IDGREAVL L +K+ +EDPA ++ L
Sbjct: 388 NYLALSYDHRIIDGREAVLSLVAMKDALEDPARLLLDL 425
>UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase;
n=8; Bacteria|Rep: Dihydrolipoamide succinyl transferase
- Rhizobium loti (Mesorhizobium loti)
Length = 424
Score = 274 bits (673), Expect = 1e-72
Identities = 128/218 (58%), Positives = 165/218 (75%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RLK+AQ+T AMLTTFNE+DMS +MA R K+ D F KKH +KLG M F KA +AL
Sbjct: 207 IARRLKEAQSTAAMLTTFNEVDMSAVMALRTKYKDVFEKKHGVKLGFMGFFTKAVTHALK 266
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P VNA I+ +IIY+++ + VAV T KGLVVPV+R+ M+ A+IE I L AR
Sbjct: 267 EIPAVNAEIDGTDIIYKNFAHVGVAVGTEKGLVVPVVRDADQMSIAEIEKEIGRLGIAAR 326
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKL++ +M GGTFTISNGGV+GSLM TPI+N PQS ILGMH I +RP+ + GQ+VIRPM
Sbjct: 327 DGKLSVADMQGGTFTISNGGVYGSLMSTPILNAPQSGILGMHKIQDRPVVVGGQIVIRPM 386
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MY+AL+YDHR++DG+EAV FL ++KE +EDP +V L
Sbjct: 387 MYLALSYDHRIVDGKEAVTFLVRVKESLEDPERLVLDL 424
>UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue
succinyltransferase component of 2-oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep: Probable
dihydrolipoyllysine-residue succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial precursor - Schizosaccharomyces pombe
(Fission yeast)
Length = 452
Score = 272 bits (667), Expect = 6e-72
Identities = 130/219 (59%), Positives = 165/219 (75%), Gaps = 4/219 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RLK++QN A LTTFNE DMS ++A RKK+ D K+ +K+G MS F KA A+
Sbjct: 232 IAERLKESQNRAASLTTFNECDMSAVVALRKKYKDEILKETGVKIGFMSFFSKACTQAMK 291
Query: 182 DQPVVNAVIEE----NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLA 349
P +N IE + ++YRD+ D+S+AVATPKGLV PVIRN ++M+ +IE IA L
Sbjct: 292 QIPAINGSIEGEGKGDTLVYRDFCDLSIAVATPKGLVTPVIRNAESMSLLEIESAIATLG 351
Query: 350 EKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVV 529
KAR GKL IE+M GTFTISNGG+FGSL GTPIIN PQ+A+LG+H I ERP+ +NGQVV
Sbjct: 352 SKARAGKLAIEDMASGTFTISNGGIFGSLYGTPIINLPQTAVLGLHAIKERPVVINGQVV 411
Query: 530 IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
RPMMY+ALTYDHR++DGREAV FLR +KE +EDPA ++
Sbjct: 412 PRPMMYLALTYDHRMVDGREAVTFLRLVKEYIEDPAKML 450
>UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=79; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bartonella quintana (Rochalimaea quintana)
Length = 410
Score = 272 bits (667), Expect = 6e-72
Identities = 126/218 (57%), Positives = 164/218 (75%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RLKDAQNT AMLTTFNE+DMS +M RK++ D F KKH +KLG M F KA +AL
Sbjct: 193 IARRLKDAQNTAAMLTTFNEVDMSAVMDLRKRYKDLFEKKHGVKLGFMGFFTKAVCHALK 252
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P VNA I+ +I+Y++YV+ +AV T KGLVVPV+R+ M+ A+IE I+ L AR
Sbjct: 253 EFPTVNAEIDGTDIVYKNYVNAGIAVGTDKGLVVPVVRDADQMSLAEIEKEISRLGRLAR 312
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKL + +M GGTFTI+NGGV+GSLM TPI+N PQS ILGMH I ER + + GQ++I PM
Sbjct: 313 DGKLAVSDMQGGTFTITNGGVYGSLMSTPILNAPQSGILGMHAIKERAMVVGGQIIICPM 372
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MY+AL+YDHR++DG+EAV FL ++KE +EDP +V L
Sbjct: 373 MYLALSYDHRIVDGQEAVTFLVRVKESLEDPERLVLDL 410
>UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=11;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
subunit, dihydrolipoamide succinyltransferase -
Magnetococcus sp. (strain MC-1)
Length = 446
Score = 270 bits (663), Expect = 2e-71
Identities = 127/216 (58%), Positives = 172/216 (79%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQRLK+AQNT AMLTTFNE+DM+ +MA R ++ + F K++ +LG MS FVKAA +AL
Sbjct: 228 IAQRLKEAQNTAAMLTTFNEVDMTAVMALRSQYKEVFEKRNHARLGFMSFFVKAAISALQ 287
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P VNA I+ NEI++++Y DI VAV +P+GLVVPV+R M+ A IE TIAG+ ++AR
Sbjct: 288 EFPAVNAEIQGNEIVFKNYYDIGVAVGSPQGLVVPVLRGADAMSLAGIESTIAGMGKRAR 347
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRP 538
G+L++EEM GGTFTI+NGG+FGSL+ TPI+N PQSAILGMH I +R + + +G + RP
Sbjct: 348 DGQLSMEEMSGGTFTITNGGIFGSLLSTPILNTPQSAILGMHKIQQRAMVMPDGSIQARP 407
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MMY+AL+YDHR++DG+EAV FL +IK+ +EDPA I+
Sbjct: 408 MMYLALSYDHRIVDGKEAVSFLVRIKDCIEDPARIL 443
>UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=24; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Escherichia coli O157:H7
Length = 405
Score = 270 bits (662), Expect = 2e-71
Identities = 128/215 (59%), Positives = 167/215 (77%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+RL +A+N+ AMLTTFNE++M IM RK++ + F K+H I+LG MS +VKA AL
Sbjct: 188 VAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALK 247
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VNA I+ ++++Y +Y D+S+AV+TP+GLV PV+R+V + ADIE I LA K R
Sbjct: 248 RYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADIEKKIKELAVKGR 307
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKLT+E++ GG FTI+NGGVFGSLM TPIINPPQSAILGMH I +RP+A+NGQV I PM
Sbjct: 308 DGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILPM 367
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+AL+YDHRLIDGRE+V FL IKE +EDP ++
Sbjct: 368 MYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLL 402
>UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Trichocomaceae|Rep: Dihydrolipoamide succinyltransferase
- Aspergillus oryzae
Length = 448
Score = 269 bits (660), Expect = 4e-71
Identities = 126/215 (58%), Positives = 170/215 (79%), Gaps = 1/215 (0%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A+RLK++QNT A LTTFNE DMS IMA R ++ D +KH +KLG M P +A+A AL +
Sbjct: 232 AERLKESQNTAAFLTTFNEADMSKIMALRSQNKDDVLQKHGVKLGFMGPVARASALALRE 291
Query: 185 QPVVNAVIEENE-IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +NA IE ++ I++ DY+D+SVAVATPKGLV PV+RN++ +IE IA L +KAR
Sbjct: 292 IPAINASIENDDTIVFHDYIDLSVAVATPKGLVTPVLRNMERQGIVEIEQGIAELGKKAR 351
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKLT++++ GG+FTISN G++GSL GTPIIN PQ+A+LG++GI +RP+A++GQV IRPM
Sbjct: 352 DGKLTMDDLVGGSFTISNSGIWGSLFGTPIINIPQTAVLGIYGIQQRPVAIDGQVEIRPM 411
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY ALTYDHRL+DGREAV FL +K+ +EDPA+++
Sbjct: 412 MYTALTYDHRLVDGREAVTFLTLVKKYLEDPASML 446
>UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Dichelobacter nodosus (strain
VCS1703A)
Length = 341
Score = 268 bits (657), Expect = 9e-71
Identities = 124/218 (56%), Positives = 168/218 (77%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I++RL + Q T AMLTTFNEI+M +M +R + F KK+ +KLGLMS FV+AA AL
Sbjct: 124 ISERLLNVQQTTAMLTTFNEINMQAVMNYRHDFQNDFVKKYGVKLGLMSFFVRAAVAALR 183
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
PV+NA+I+ ++++YR Y +I +AVA+P+GLVVP++RN + +++ADIE I AEKA
Sbjct: 184 QFPVINAMIDGDDVVYRRYCNIGIAVASPRGLVVPILRNAETLSFADIERQIKIFAEKAA 243
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G L++EE+ GTFTI+NGG FGS++ TPI+NPPQSAILGMH I +RP+ NG +VIRP+
Sbjct: 244 DGSLSLEEISDGTFTITNGGTFGSMLSTPILNPPQSAILGMHAIVDRPMVENGAIVIRPV 303
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MY+AL+YDHRLIDGREAVLFL+ IK +E PA ++ L
Sbjct: 304 MYVALSYDHRLIDGREAVLFLKTIKNMLEAPARLLLDL 341
>UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransferase
(Component of 2- oxoglutarate dehydrogenase complex)
protein; n=4; Bacteria|Rep: SucB; dihydrolipoamide
succinyltransferase (Component of 2- oxoglutarate
dehydrogenase complex) protein - Nitrosomonas europaea
Length = 425
Score = 267 bits (655), Expect = 2e-70
Identities = 125/213 (58%), Positives = 165/213 (77%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +Q+T A+LTTFNE++M IM R ++ D+F K+H IKLG S FVKA AL
Sbjct: 208 IAERLVQSQSTAAILTTFNEVNMQAIMDLRARYKDSFEKEHGIKLGFTSFFVKAVVAALK 267
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P++NA ++ N+IIY DY DI +AVA+P+GLVVP+IR+ +T+A IE IA LA +A+
Sbjct: 268 KFPIINASVDGNDIIYHDYYDIGIAVASPRGLVVPIIRDADKLTFAGIEKQIADLARRAQ 327
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKLT+EE+ GGTF+I+NGGVFGS++ TPIINPPQSAILG+H +RP+ NGQ+VIRP+
Sbjct: 328 EGKLTLEELTGGTFSITNGGVFGSMLSTPIINPPQSAILGIHATKQRPVVENGQIVIRPI 387
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPAT 640
Y+AL+YDHR+IDGREAVL L IKE +E P +
Sbjct: 388 NYLALSYDHRIIDGREAVLSLVAIKEALEYPVS 420
>UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase
component; n=6; Anaplasmataceae|Rep: Dihydrolipoamide
acetyltransferase component - Anaplasma marginale
(strain St. Maries)
Length = 437
Score = 267 bits (655), Expect = 2e-70
Identities = 124/211 (58%), Positives = 163/211 (77%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RLK++QNT A L+TFNE+DMS +MA R K+ + F KK+ +KLG MS F++A AL
Sbjct: 220 IASRLKESQNTAATLSTFNEVDMSAVMALRGKYKEGFEKKYEVKLGFMSFFIRAVVLALR 279
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ PV+NA I +EIIYRDY +I VAV T KGLVVPVIR + M++A +E + L++KAR
Sbjct: 280 EIPVINAEISGDEIIYRDYCNIGVAVGTDKGLVVPVIRGAETMSFAALEQELVMLSKKAR 339
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G LT+ +M G TFTI+NGGV+GSL+ TPIINPPQS ILGMH I ERP+ +NG + IRPM
Sbjct: 340 GGTLTVADMSGATFTITNGGVYGSLLSTPIINPPQSGILGMHAIQERPVVVNGNIEIRPM 399
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
MY+AL+YDHR++DG+ AV FL ++K+ +EDP
Sbjct: 400 MYLALSYDHRIVDGQGAVTFLVRVKQYIEDP 430
>UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=135; root|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Rickettsia felis (Rickettsia azadi)
Length = 401
Score = 267 bits (655), Expect = 2e-70
Identities = 126/218 (57%), Positives = 168/218 (77%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQRLKD+QNT A+LTTFNEIDMS ++A R ++ + F KKH +KLG MS FVKA AL
Sbjct: 184 IAQRLKDSQNTAAILTTFNEIDMSKVIALRNQYKEEFEKKHLVKLGFMSFFVKATIEALK 243
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VNA I+ ++++Y++Y DI VAV T +GLVVPV+R+ M +A++E I LA+KAR
Sbjct: 244 LIPSVNAEIDGDDLVYKNYYDIGVAVGTEQGLVVPVVRDADKMGFAEVEKAIGTLAKKAR 303
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKL++ ++ GGTF+ISNGGV+GSL+ TPIINPPQS ILG+H ER + ++G++ IRPM
Sbjct: 304 EGKLSMADLSGGTFSISNGGVYGSLLSTPIINPPQSGILGLHKTEERAVVIDGKIEIRPM 363
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MYIAL+YDHR+IDG+E V FL KIKE +E+P ++ L
Sbjct: 364 MYIALSYDHRIIDGKEGVSFLVKIKELIENPEKLLLNL 401
>UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=10;
Bacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Rhodopirellula baltica
Length = 435
Score = 266 bits (651), Expect = 5e-70
Identities = 126/214 (58%), Positives = 160/214 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RL AQ T A+LTTFNEI+M+ +MA R K+ D F KKH +KLG MS F KA AL
Sbjct: 218 IASRLVQAQQTAALLTTFNEINMAPVMAIRSKYKDAFAKKHGVKLGFMSFFAKATVEALR 277
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VNA I + ++YR+Y DI +A+ KGLVVPV+RNV+ M++A++E +IA A A
Sbjct: 278 RYPAVNAEIRGDSMVYRNYQDIGIAIGGGKGLVVPVLRNVERMSFAEVEGSIAEYARLAG 337
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
+L ++ GGTFTISNGG++GSL+ TPI+NPPQS ILG+H I ERP+A +GQVVIRPM
Sbjct: 338 ENRLQPSDLMGGTFTISNGGIYGSLLSTPIVNPPQSGILGLHSIQERPVAEDGQVVIRPM 397
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATI 643
MY+ALTYDHR++DGREAV FL IKE +EDPA +
Sbjct: 398 MYVALTYDHRIVDGREAVGFLVAIKETIEDPARL 431
>UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Geobacter|Rep: Dihydrolipoamide succinyltransferase -
Geobacter metallireducens (strain GS-15 / ATCC 53774 /
DSM 7210)
Length = 418
Score = 265 bits (649), Expect = 9e-70
Identities = 119/211 (56%), Positives = 158/211 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL A+ AMLTTFNE D+ +M RKK+ + F KKH + LG MS FVKA AL
Sbjct: 201 IAERLLVARQQTAMLTTFNEADLGRVMELRKKYKEHFQKKHGVSLGFMSFFVKACVEALK 260
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P VN IE ++I++ Y I +A+ KGLVVPV+R+ +++A+IE TIAG AEK +
Sbjct: 261 EYPAVNGSIEGDDIVFHHYYHIGIAIGAEKGLVVPVLRDADRLSFAEIETTIAGFAEKTK 320
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
+L + ++ GGTFTISNGGV+GSL+ TPI+NPPQS +LGMH + ERP+ +GQ+VIRPM
Sbjct: 321 ANRLELSDLQGGTFTISNGGVYGSLLSTPILNPPQSGVLGMHAVQERPVVRDGQIVIRPM 380
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
MY+AL+YDHR+IDGREAV FL+K+KE VE+P
Sbjct: 381 MYLALSYDHRIIDGREAVGFLKKVKEYVEEP 411
>UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrobacter hamburgensis (strain X14 / DSM 10229)
Length = 413
Score = 265 bits (649), Expect = 9e-70
Identities = 123/218 (56%), Positives = 162/218 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RLK+ QNT AMLTTFNE+DM+ +M R + + F KKH +KLG M F KA AL
Sbjct: 196 IARRLKEVQNTAAMLTTFNEVDMTGVMTLRTHYKEVFEKKHGVKLGFMGFFTKACVQALK 255
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
D P NA I+ ++IY++Y I +AV T KGLVVPV+R+ + A+IE +IA +AR
Sbjct: 256 DIPAANAEIDGTDLIYKNYYHIGIAVGTDKGLVVPVVRDCDRKSIAEIEKSIADYGRRAR 315
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G+L I+EM GGTFTI+NGG++GSLM TPI+N PQ+ ILGMH I ERP+A+ G+V IRPM
Sbjct: 316 DGQLKIDEMQGGTFTITNGGIYGSLMSTPILNAPQAGILGMHKIQERPMAIAGKVEIRPM 375
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MY+AL+YDHR+IDG++AV FL ++KE +EDPA +V L
Sbjct: 376 MYLALSYDHRVIDGKDAVTFLVRVKESLEDPARLVLDL 413
>UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Chloroflexus|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Chloroflexus aggregans DSM 9485
Length = 469
Score = 265 bits (649), Expect = 9e-70
Identities = 125/215 (58%), Positives = 161/215 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +AQ+T AMLTTFNE+DMS +MA R +H D+F ++H + LG MS F KA AL
Sbjct: 252 IARRLVEAQHTAAMLTTFNEVDMSAVMALRARHKDSFKERHGVSLGYMSFFTKAVVGALK 311
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P+VNA I+ E++ + Y DI +AV +GLVVPV+R+ T+A IE IA LA+KAR
Sbjct: 312 AFPMVNAEIQGEEVVIKYYYDIGIAVGVDEGLVVPVVRDADRKTFAQIEREIAQLAKKAR 371
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G L++ E+ GGTFTI+NGGV+GSLM TPI+N PQ ILGMH I ERP+ +NGQ+VIRPM
Sbjct: 372 EGTLSLAELQGGTFTITNGGVYGSLMSTPILNAPQVGILGMHKIEERPVVVNGQIVIRPM 431
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+AL+YDHRLIDG AV FL K+KE +EDP ++
Sbjct: 432 MYVALSYDHRLIDGSTAVRFLVKVKELIEDPEALL 466
>UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 415
Score = 264 bits (648), Expect = 1e-69
Identities = 129/218 (59%), Positives = 162/218 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQRL DAQ A+L+TFNEIDMS +M RK+H D F KH I LG MS F KA A AL
Sbjct: 198 IAQRLVDAQQEAAILSTFNEIDMSAVMNLRKQHKDEFKDKHEIGLGFMSFFTKATAIALK 257
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P++NA ++ N IIY D+VD+ +AV+TPKGLVVPVIR+ + ++ IE I LA K R
Sbjct: 258 EFPIMNAQVDGNSIIYHDFVDMGIAVSTPKGLVVPVIRDCDQLNFSGIERKIRELALKGR 317
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
LT EEM GGTFTI+NGG FGS++ TPI+N PQSAILGMH I ERP+A+NGQV +RP+
Sbjct: 318 DMDLTPEEMTGGTFTITNGGTFGSMLSTPILNRPQSAILGMHNIVERPVAVNGQVEVRPI 377
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MY+A++YDHR+IDG +AV FL KIK +EDP ++ L
Sbjct: 378 MYLAVSYDHRIIDGSDAVRFLVKIKTLLEDPTRMLLEL 415
>UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=7; Flavobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Gramella forsetii (strain KT0803)
Length = 438
Score = 262 bits (642), Expect = 6e-69
Identities = 123/215 (57%), Positives = 162/215 (75%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+RL A+N AMLTTFNE+DMS I RKK+ + F KH + LG MS F A AL
Sbjct: 213 LAERLVSAKNDTAMLTTFNEVDMSPIFELRKKYKEEFKDKHGVSLGFMSFFTLAVIRALD 272
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P VN++I+ + I DY DIS+AV+ PKGL VPVIRN +N+++ +E + LA KAR
Sbjct: 273 EYPAVNSMIDGDYQISYDYKDISIAVSGPKGLTVPVIRNAENLSFRGVESEVKRLAIKAR 332
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GK+T++EM GGTFTI+NGGVFGS++ TPIINPPQSAILGMH I ERP+A++G V IRP+
Sbjct: 333 DGKITVDEMTGGTFTITNGGVFGSMLSTPIINPPQSAILGMHNIVERPVAIDGHVEIRPI 392
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+AL+YDHR+IDG+E+V FL IKE +E+P ++
Sbjct: 393 MYVALSYDHRIIDGKESVGFLVAIKEALENPEELL 427
>UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase component;
n=17; Bacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
component - Vibrio vulnificus
Length = 402
Score = 262 bits (641), Expect = 8e-69
Identities = 124/215 (57%), Positives = 166/215 (77%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A RL +A+N+ AMLTTFNE++M IM RK++ D F +H I+LG MS +VKA AL
Sbjct: 185 VANRLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGDQFEARHGIRLGFMSFYVKAVTEALK 244
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +NA I+ ++I+Y +Y DIS+AV+TP+GLV PV+++ + +AD+E I LA K R
Sbjct: 245 RYPEINASIDGDDIVYHNYFDISMAVSTPRGLVTPVLKDCDTLGFADVEKGIKELAIKGR 304
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKLT++E+ GG FTI+NGGVFGSLM TPIINPPQSAILGMH I +RP+A++G+V I PM
Sbjct: 305 DGKLTVDELIGGNFTITNGGVFGSLMSTPIINPPQSAILGMHKIQDRPMAVDGKVEILPM 364
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+AL+YDHRLIDGRE+V FL +KE +EDPA ++
Sbjct: 365 MYLALSYDHRLIDGRESVGFLVTVKELLEDPARLL 399
>UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase, putative; n=12;
cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase, putative
- Plasmodium yoelii yoelii
Length = 1632
Score = 261 bits (639), Expect = 1e-68
Identities = 123/211 (58%), Positives = 161/211 (76%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RLK++QNT A+LTTFNE DMS + R + D F KK+ KLG +S F+ A+ AL
Sbjct: 1415 IAERLKESQNTCALLTTFNECDMSKAIVLRTELKDIFQKKYGCKLGFVSLFLYASTLALK 1474
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VNA I+ +EI+Y++Y+DISVAVATP GL VPVIR+ QN +EL ++ +A KA+
Sbjct: 1475 KMPQVNAYIDNDEIVYKNYIDISVAVATPNGLTVPVIRDCQNKNLPQLELALSDIAAKAK 1534
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KL++++ GGTFTISNGGVFGS++ TPIIN PQSAILGMH I RP+ +N ++VIRP+
Sbjct: 1535 NNKLSLDDFTGGTFTISNGGVFGSMLSTPIINMPQSAILGMHTIKNRPVVVNNEIVIRPV 1594
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
MY+ALTYDHRL+DGREAV FL IK+ +E+P
Sbjct: 1595 MYLALTYDHRLLDGREAVQFLCAIKDYIENP 1625
>UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (E2)
of 2-oxoglutarate dehydrogenase; n=6; cellular
organisms|Rep: Dihydrolipoamide succinyl transferase
(E2) of 2-oxoglutarate dehydrogenase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 369
Score = 259 bits (635), Expect = 4e-68
Identities = 122/219 (55%), Positives = 164/219 (74%), Gaps = 1/219 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHS-IKLGLMSPFVKAAANAL 178
IA+ LK AQNT A+LTTFNEIDMS A R ++ + F KKH +LG MS F +A AL
Sbjct: 151 IARNLKAAQNTAAILTTFNEIDMSAAKALRAQYKEEFEKKHDGARLGFMSFFARAVVGAL 210
Query: 179 MDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
D P +NA IE +EI+YRD+V++ +AV T +GLVVPV+ + M++A++E IA ++A
Sbjct: 211 KDYPAINAQIEGDEIVYRDFVNLGIAVGTERGLVVPVLHDADQMSFAELERRIADYGKRA 270
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRP 538
RTG L +EE+ GTF+I+NGG+FGSL+ TPI+N PQS ILGMH I +RP+ +GQ+VIRP
Sbjct: 271 RTGGLKLEELSHGTFSITNGGIFGSLLSTPILNTPQSGILGMHAIQDRPVVRDGQIVIRP 330
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MMY+AL+YDHR++DGREAV FL +IK+ VEDP ++ L
Sbjct: 331 MMYVALSYDHRIVDGREAVSFLVRIKQLVEDPRRLLLDL 369
>UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: 2-oxoglutarate
dehydrogenase, E2 subunit, dihydrolipoamide
succinyltransferase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 444
Score = 257 bits (630), Expect = 2e-67
Identities = 119/215 (55%), Positives = 161/215 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA + A+ AMLTTFNEIDMS + RK+ D F KKHS+ LG+MS F+KAAA AL
Sbjct: 227 IADHMLQARLNTAMLTTFNEIDMSRLQEIRKQFRDLFQKKHSVSLGIMSFFLKAAAVALK 286
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P +NA IE +EI+Y +Y+ I VAV +GLVVPVIR+V + +AD+E I K R
Sbjct: 287 ELPELNAFIEGHEIVYHNYIHIGVAVGAERGLVVPVIRDVDKLGFADLEKAILDHVRKIR 346
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
+L + +++GGTFTISNGGV+GSLM TPI+N PQS ILG+H I +RP+ ++G++V+RPM
Sbjct: 347 ENRLEMSDLEGGTFTISNGGVYGSLMSTPILNSPQSGILGLHKIEDRPVVVDGRIVVRPM 406
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+AL+YDHR++DGREAV FL++IKE +E+P I+
Sbjct: 407 MYVALSYDHRIVDGREAVTFLKRIKECIENPERIM 441
>UniRef50_Q6MC86 Cluster: Probable dihydrolipoamide
S-succinyltransferase, (2-oxogluturate dehydrogenase
complex E2 component), sucB; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Probable
dihydrolipoamide S-succinyltransferase, (2-oxogluturate
dehydrogenase complex E2 component), sucB -
Protochlamydia amoebophila (strain UWE25)
Length = 404
Score = 257 bits (629), Expect = 2e-67
Identities = 119/218 (54%), Positives = 161/218 (73%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RL +AQ T AMLTTFNE+D+S I++ R+KH + F KK+ IKLG MS FVKA +AL
Sbjct: 187 IANRLIEAQQTMAMLTTFNEVDLSEIISLREKHQEIFIKKYGIKLGFMSFFVKAVVSALK 246
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN+ +++ +I+ R Y DI +AV T +G VPV+R ++A IEL I A+KAR
Sbjct: 247 AFPTVNSYLDQQDIVERHYYDIGIAVGTERGTFVPVVRQCDQQSFAQIELAIDLFAKKAR 306
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GK+ ++++ GG FTI+NGGV+GSL+ TPI+NPPQ AILGMH I +RP+ + Q+VIRPM
Sbjct: 307 DGKIAMDDLQGGGFTITNGGVYGSLLSTPILNPPQCAILGMHKIEKRPVVMEDQIVIRPM 366
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MY+AL+YDHRLIDG+E+V FL IK +EDP+ ++ L
Sbjct: 367 MYLALSYDHRLIDGKESVAFLVHIKNALEDPSRLLLNL 404
>UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=4;
Bacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrococcus mobilis Nb-231
Length = 443
Score = 252 bits (617), Expect = 7e-66
Identities = 119/215 (55%), Positives = 156/215 (72%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +AQ AMLTTFNE +M IM+ R ++ + F + H IKLG+MS FVK AL
Sbjct: 226 IAERLVEAQQNTAMLTTFNECNMQPIMSLRNRYKERFERYHGIKLGIMSFFVKTVIEALK 285
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VNA I+ +IIY Y DI +AV+T +GL+VPV+R+ + +A+IE IA +AR
Sbjct: 286 RFPAVNASIDGKDIIYHGYYDIGIAVSTERGLLVPVLRDADQLGFAEIEQAIADFGRRAR 345
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
K+ I+E+ GGTFTI+NGG+FGSLM TPI+NPPQS ILGMH I +RP+ N V +RPM
Sbjct: 346 ESKIHIDELTGGTFTITNGGIFGSLMSTPILNPPQSGILGMHRIQDRPVVENAAVTVRPM 405
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+AL+YDHR+IDGREAV FL IKE +EDP+ ++
Sbjct: 406 MYLALSYDHRIIDGREAVQFLVTIKELLEDPSRLL 440
>UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=15; Proteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Baizongia pistaciae
Length = 410
Score = 252 bits (617), Expect = 7e-66
Identities = 118/218 (54%), Positives = 162/218 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I++RL +N A LTTFNE++M I+ R+K+ + F +KH IKLGLMS +VKA AL
Sbjct: 193 ISERLLSTKNNTASLTTFNEVNMQSILNLRRKYGELFKQKHGIKLGLMSFYVKAVIEALK 252
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +NA I+ +EIIY +Y DIS+A++TP+GLV PV++N M+ A+IE+ I +EK +
Sbjct: 253 IFPEINASIDNDEIIYYNYFDISIAISTPRGLVTPVLKNADLMSMAEIEIKIKDFSEKGK 312
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KLTI+++ GG FTI+NGGVFGSL TP+INPPQSAILGMH I +RP+ ++ + + PM
Sbjct: 313 NSKLTIDDLIGGNFTITNGGVFGSLFSTPLINPPQSAILGMHAIHKRPVIVDENIEVHPM 372
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MY+AL+YDHRLIDG+E+V FL KIKE +ED + IV +
Sbjct: 373 MYLALSYDHRLIDGKESVGFLLKIKEFLEDFSRIVLNI 410
>UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase; n=2;
Desulfuromonadales|Rep: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 396
Score = 250 bits (613), Expect = 2e-65
Identities = 117/211 (55%), Positives = 158/211 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+RL A+ AM TT NE D+S IM R ++ + F +++ IKLGLMS FVKA AL
Sbjct: 180 VARRLLAARQQTAMATTINEADLSRIMELRSQYGERFMERNGIKLGLMSFFVKACVEALR 239
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ PV+NA +EE I+Y+ + DI +AVAT +GLV PV+ N + +ADIE IA LAEKAR
Sbjct: 240 EFPVINARLEEEAIVYQHFYDIGIAVATDQGLVAPVLLNADRLNFADIEKQIAELAEKAR 299
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
+L + ++ GGTF+ISNGGV+GSL+ TP++NPPQSAILGMH I +RP+ + Q+V RPM
Sbjct: 300 KHRLALADLQGGTFSISNGGVYGSLLSTPLLNPPQSAILGMHSIQQRPVVRDDQIVARPM 359
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
MY+AL+YDHRLIDGR+AV FL+++ E VE+P
Sbjct: 360 MYLALSYDHRLIDGRDAVNFLKRVVERVEEP 390
>UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10947.1 - Gibberella zeae PH-1
Length = 442
Score = 250 bits (612), Expect = 3e-65
Identities = 115/217 (52%), Positives = 164/217 (75%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RLK +QNT A LTT E+DMS+++A+R K+ + ++H ++LG M F KA A
Sbjct: 224 IAGRLKQSQNTCASLTTIQEVDMSNLIAWRAKYKEEVAEEHGVRLGYMGAFTKATTIAAQ 283
Query: 182 DQPVVNAVIE-ENEII-YRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P +NA I+ E EII Y DYVD+S+AV+ PKGLV PV+RN ++++ ++E +A A+K
Sbjct: 284 KVPQINAQIDTEKEIITYHDYVDVSIAVSAPKGLVTPVLRNTESLSIVELERAVAAAAKK 343
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR GKLT+E+M+GG+F+ISN G+FGS+ GTP+IN PQ+A+ M+GI + +A+NG+ VIR
Sbjct: 344 ARDGKLTMEDMEGGSFSISNPGIFGSMFGTPVINYPQAAVFNMNGIRQEVVAINGEAVIR 403
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
PMMYI+LTYDHRLIDGREA +FL +K+ +EDP+ ++
Sbjct: 404 PMMYISLTYDHRLIDGREASMFLNTVKKYIEDPSRML 440
>UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Thiobacillus denitrificans ATCC 25259|Rep:
Dihydrolipoamide succinyltransferase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 379
Score = 249 bits (609), Expect = 6e-65
Identities = 118/211 (55%), Positives = 157/211 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+RL AQ+T AMLTTFNE++M + R++ F +H +KLG MS FV+A AL
Sbjct: 160 VAERLVAAQHTAAMLTTFNEVNMQPVNELRQRFKADFEVRHGVKLGYMSFFVRAVCRALE 219
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P+VNA I+ N+I++ DI +A+++P+GLVVP++R Q ++ +IE IA A +AR
Sbjct: 220 AFPIVNARIDGNDIVWHGDADIGIAISSPRGLVVPILRRAQQLSSDEIERAIADFARRAR 279
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KL +EE+ GGTF+I+NGGVFGSL+ TPI+NPPQSAILGMH I ERP+A +GQVVIRPM
Sbjct: 280 DSKLALEELAGGTFSITNGGVFGSLLSTPILNPPQSAILGMHTIQERPVAEHGQVVIRPM 339
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
MY+ALTYDHRLIDGR+AV FL +K +E P
Sbjct: 340 MYLALTYDHRLIDGRDAVQFLVAVKAALEAP 370
>UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Acyrthosiphon pisum
(Acyrthosiphon pisumsymbiotic bacterium)
Length = 420
Score = 248 bits (608), Expect = 8e-65
Identities = 117/210 (55%), Positives = 157/210 (74%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL D++N AMLTTF+E++M I+ RKK+ + F KKH++++G MS FVKA AL
Sbjct: 203 IAERLLDSKNNTAMLTTFHEVNMKPIILLRKKYGEDFEKKHNVRIGFMSFFVKAVIQALK 262
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P +NA I++ +I++ DIS+A++TP+GL+ PVIRN MT A+IE I + K
Sbjct: 263 NFPEINAYIDQTDIVFYKNFDISIAISTPRGLITPVIRNADTMTMAEIEKKIKDFSIKGL 322
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
K+ I+E+ GG FTI+NGGVFGSLM TPIINPPQ+AILGMH I ERP+ +NGQ+ I PM
Sbjct: 323 QNKINIKELMGGNFTITNGGVFGSLMSTPIINPPQTAILGMHVIQERPVVVNGQIKILPM 382
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVED 631
MY+AL+YDHRLIDG+E+V FL IK +ED
Sbjct: 383 MYLALSYDHRLIDGKESVGFLINIKNILED 412
>UniRef50_O84058 Cluster: Dihydrolipoamide Succinyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Succinyltransferase
- Chlamydia trachomatis
Length = 365
Score = 246 bits (603), Expect = 3e-64
Identities = 116/215 (53%), Positives = 157/215 (73%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I++RL + + +AMLTTFNEI M ++A RK+ + F K+ +KLG MS FV+A ++L
Sbjct: 149 ISRRLVQSLHDSAMLTTFNEIHMGPLIALRKERQEDFVAKYGVKLGFMSFFVRAVVDSLK 208
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VNA IE+NEI+YR Y DIS+A+ T +GLVVPVIRN ++ +IEL +A LA +AR
Sbjct: 209 KYPRVNAYIEDNEIVYRHYYDISIAIGTDRGLVVPVIRNCDQLSSGEIELQLADLASRAR 268
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKL I E++GG FTI+NGGV+GSL+ TPIINPPQ ILGMH I +RP+ +VI M
Sbjct: 269 EGKLAIHELEGGGFTITNGGVYGSLLSTPIINPPQVGILGMHKIEKRPVVREDAIVIADM 328
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MY+A++YDHR+IDG+EAV FL +KE +E P ++
Sbjct: 329 MYVAMSYDHRIIDGKEAVGFLVNVKEQLEQPELLL 363
>UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial, putative; n=2; Theileria|Rep:
Dihydrolipoamide succinyltransferase component of
2-oxoglutarate dehydrogenase complex, mitochondrial,
putative - Theileria annulata
Length = 457
Score = 244 bits (597), Expect = 2e-63
Identities = 118/215 (54%), Positives = 163/215 (75%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RLK AQ N MLTTFNE DMS + RK ++ + S KLG +S F++A+ AL+
Sbjct: 243 IAERLKLAQTENVMLTTFNECDMSELTKVRKMLNES--GEVSCKLGFVSAFMRASTLALL 300
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P++N+ I+ E++ ++YVDISVAVATP GL+VPVIRN + + ++EL++ +A+KAR
Sbjct: 301 KMPIMNSYIDGKEMVTKNYVDISVAVATPTGLLVPVIRNCEFKNWEELELSLLEMAKKAR 360
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G +TIE+M GGTFTISNGGV+GSL+ TPIINPPQS+ILGMH I +R + + +VIRP+
Sbjct: 361 DGSITIEDMTGGTFTISNGGVYGSLLSTPIINPPQSSILGMHAITKRAVVRDDNIVIRPV 420
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M +ALTYDHRLIDGR+AV FL IK+ +E+P+ ++
Sbjct: 421 MNVALTYDHRLIDGRDAVTFLNTIKKFIENPSLLL 455
>UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase,
putative; n=1; Babesia bovis|Rep: Dihydrolipoamide
succinyltransferase, putative - Babesia bovis
Length = 402
Score = 244 bits (597), Expect = 2e-63
Identities = 116/215 (53%), Positives = 162/215 (75%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I +RLK++Q T ML+TFNE DM IMA RK+ ++ K+ +KLG +S ++KA+ AL+
Sbjct: 188 IGERLKESQQTTVMLSTFNECDMDAIMALRKELNES--GKYPVKLGYVSAYMKASTMALL 245
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P++N+ IE ++I+ + +VDISVAVATP GLVVPVIRN + ++ ++E + A K R
Sbjct: 246 KMPIMNSYIEGDDIVTKHFVDISVAVATPTGLVVPVIRNCEGKSWIELEQQLVDAAAKGR 305
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G+LT+ +M GGTFTISNGGV+GS++ TPIINPPQS+ILGMH I +R + + Q+VIRP+
Sbjct: 306 EGRLTVADMTGGTFTISNGGVYGSVLSTPIINPPQSSILGMHSIIKRCVVRDDQMVIRPI 365
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M +AL+YDHRLIDGREAV FL IKE +E+P ++
Sbjct: 366 MNLALSYDHRLIDGREAVQFLIAIKEAIENPKVLL 400
>UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=95; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bacillus subtilis
Length = 417
Score = 236 bits (577), Expect = 5e-61
Identities = 115/216 (53%), Positives = 157/216 (72%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL + Q T+AMLTTFNE+DM+ +M RK+ D F +++ +KLG MS F KA AL
Sbjct: 199 IAKRLVEVQQTSAMLTTFNEVDMTAVMNLRKRRKDQFFEQNEVKLGFMSFFTKAVVAALK 258
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P++NA I+ +E+I + + DI +AVA +GLVVPV+R+ +T+A IE I LA+KAR
Sbjct: 259 KYPLLNAEIQGDELIVKKFYDIGIAVAAVEGLVVPVVRDADRLTFAGIEKEIGELAKKAR 318
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQ-VVIRP 538
KLT+ E++GG+FTI+NGG FGSLM TPI+N PQ ILGMH I RP+A++ + RP
Sbjct: 319 NNKLTLSELEGGSFTITNGGTFGSLMSTPILNSPQVGILGMHKIQLRPVAIDEERFENRP 378
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MMYIAL+YDHR++DG+EAV FL IK +EDP ++
Sbjct: 379 MMYIALSYDHRIVDGKEAVGFLVTIKNLLEDPEQLL 414
>UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E2 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 398
Score = 231 bits (566), Expect = 1e-59
Identities = 108/210 (51%), Positives = 148/210 (70%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I++RL AMLTTFNE++M I++ R K+ D F K+ KLG MS +VK+ AL
Sbjct: 181 ISKRLLYTVKNTAMLTTFNEVNMQPIISIRNKYKDIFENKYKSKLGFMSFYVKSVTQALK 240
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +NA IE+ IIY DY DI++A++TP+GL+ P+++N N++ +IE I
Sbjct: 241 KFPEINASIEKKNIIYHDYYDINIAISTPRGLITPILKNTDNLSIYEIEKKIKSFVLLGE 300
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKL E+++ GTFTI+NGGVFGSLM TPIINPPQ AILGMH I +RPI +N ++ I PM
Sbjct: 301 QGKLKFEDLEAGTFTITNGGVFGSLMSTPIINPPQVAILGMHHIKKRPIVVNKKIKILPM 360
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVED 631
MY+AL+YDH+LIDG++A+ FL IK+ +ED
Sbjct: 361 MYLALSYDHQLIDGKQAIQFLNYIKDILED 390
>UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=35; Bacillales|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 424
Score = 227 bits (555), Expect = 2e-58
Identities = 114/216 (52%), Positives = 153/216 (70%), Gaps = 2/216 (0%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHS-IKLGLMSPFVKAAANALM 181
A++L + N AMLTTFNEIDM+++M RK+ + F K H KLG MS F KAA AL
Sbjct: 206 AKKLLEVSNNTAMLTTFNEIDMTNVMDLRKRKKEQFIKDHDGTKLGFMSFFTKAAVAALK 265
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VNA I+ +++I + Y DI VAV+T GL+VP +R+ +A+IE I LA+KAR
Sbjct: 266 KYPEVNAEIDGDDMITKQYYDIGVAVSTEDGLLVPFVRDCDKKNFAEIEDEIGNLAKKAR 325
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVV-IRP 538
KL +++M G+FTI+NGG+FGS+M TPIIN Q+AILGMH I RPIA++ + RP
Sbjct: 326 DKKLGLDDMVNGSFTITNGGIFGSMMSTPIINGSQAAILGMHSIITRPIAIDADTIENRP 385
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MMYIAL+YDHR+IDG+EAV FL+ IKE +E+P ++
Sbjct: 386 MMYIALSYDHRIIDGKEAVGFLKTIKELIENPEDLL 421
>UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 370
Score = 216 bits (527), Expect = 5e-55
Identities = 100/138 (72%), Positives = 118/138 (85%)
Frame = +2
Query: 221 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 400
I+YRDYVDISVAVAT KGLV PV+RN ++M IE TIA L +KAR KLTIE+M GGT
Sbjct: 228 IVYRDYVDISVAVATEKGLVTPVVRNTESMDLVGIEKTIADLGKKARDNKLTIEDMAGGT 287
Query: 401 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 580
FTISNGGVFGSLMGTPIIN PQ+A+LG+H I ++P+ +NGQ+VIRPMMY+ALTYDHRL+D
Sbjct: 288 FTISNGGVFGSLMGTPIINLPQTAVLGLHAIKDKPVVVNGQIVIRPMMYLALTYDHRLLD 347
Query: 581 GREAVLFLRKIKEGVEDP 634
GREAV FL K+KE +EDP
Sbjct: 348 GREAVQFLVKVKEYIEDP 365
>UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=5; Actinomycetales|Rep: 2-oxoglutarate dehydrogenase E2
component - Kineococcus radiotolerans SRS30216
Length = 618
Score = 180 bits (437), Expect = 4e-44
Identities = 91/213 (42%), Positives = 134/213 (62%), Gaps = 4/213 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQR+K++ +A LTT E+D++ I R + D F KL + FVKAA AL
Sbjct: 396 IAQRMKESLQNSAQLTTVIEVDVTKIARLRARAKDGFLATEGAKLTFLPFFVKAAVEALK 455
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +NA I+ I+Y ++S+AV TPKGL+ PVI++ ++ + IA LA + R
Sbjct: 456 QHPSLNASIDGENIVYHGSENVSMAVDTPKGLITPVIKDAGDLNLGGLARKIADLAARTR 515
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL--NGQ--VV 529
K+T +++ GGTFTI+N G G+L TPI+N PQ AILG I +RP+ L +GQ +
Sbjct: 516 ASKITPDDLSGGTFTITNTGSIGALFDTPILNAPQVAILGTGAIVKRPVVLEVDGQETIA 575
Query: 530 IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
IR MMY+AL+YDH+++DG +A FL+ +K+ +E
Sbjct: 576 IRSMMYLALSYDHQIVDGADAARFLQTVKKRIE 608
>UniRef50_A1SJ23 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=18; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 597
Score = 165 bits (402), Expect = 7e-40
Identities = 86/216 (39%), Positives = 136/216 (62%), Gaps = 7/216 (3%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA R+ D+ T+A LT E+D+++I R + F + +KL + F KAA +AL
Sbjct: 376 IATRMVDSLQTSAQLTQVVEVDVTNIARLRDEAKADFLSREGVKLSYLPFFAKAAIDALK 435
Query: 182 DQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P +NA I E E+ Y D ++++AV T KGL+ PVI++ +++ A + IA +A++
Sbjct: 436 HHPALNATIDTEAGEVTYYDRENLAIAVDTEKGLITPVIKDAGDLSIAGLAKKIADVAQR 495
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN----GQ 523
RT K+ +E+ GGTFTI+N G G+L TPI+N PQ AILG + +RP+ ++ G+
Sbjct: 496 TRTNKIGPDELSGGTFTITNLGSVGALWDTPIVNKPQVAILGPGAVVKRPVVIDDPNLGE 555
Query: 524 -VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
+ +R M+Y+ALTYDH+L+DG +A FL +K+ +E
Sbjct: 556 TIAVRYMVYLALTYDHQLVDGADAGRFLTDVKQRLE 591
>UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Bacillus halodurans|Rep: Dihydrolipoamide
S-acetyltransferase - Bacillus halodurans
Length = 436
Score = 165 bits (401), Expect = 1e-39
Identities = 86/211 (40%), Positives = 128/211 (60%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+R+ D+ + +T EIDMS + R + L ++ +L +KA A+ALM
Sbjct: 221 VAKRMVDSAFSAPHVTITTEIDMSSTIKIRSQLLGMIEQETGYRLSYTEIVMKAVAHALM 280
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +NA ENEI+Y + V I +AVA GLVVPV+++V A + +A AR
Sbjct: 281 SHPTINASFFENEIVYHEDVHIGLAVAVEGGLVVPVVKHVDKKGLAQLTNECKTVAMAAR 340
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
+L+ E M GGTFTISN G++ + TP+IN P+SAILG+ I E+P+ ++GQ+ +RPM
Sbjct: 341 DNRLSQEMMSGGTFTISNLGMYAIDVFTPVINQPESAILGVGRIQEKPVGIDGQIELRPM 400
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
M +L++DHR+IDG A FL +K +E P
Sbjct: 401 MTASLSFDHRVIDGAPAAAFLTDVKSMLEQP 431
>UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 367
Score = 165 bits (400), Expect = 1e-39
Identities = 86/219 (39%), Positives = 136/219 (62%), Gaps = 6/219 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+R+ ++ T A LTT E+D++ I R H D F ++ IKL + F +AA +AL
Sbjct: 145 IAKRMVESLQTAAQLTTVLEVDVTAIARLRATHKDAFLQRTGIKLSFLPFFAQAAVDALA 204
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ V+NA + + E+ Y D+ + +AV + KGL+VPVIR+ Q + + IA A+K
Sbjct: 205 EHRVLNASLNTDVTEVTYYDHCHLGMAVDSAKGLMVPVIRDAQQLGIEGLAQAIADKADK 264
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFER--PIALNGQ-- 523
RTG +T +++ GGTFT++N G G+L TPIIN PQ+ ILG+ + ER P +G+
Sbjct: 265 VRTGTITADDLTGGTFTLTNTGSRGALFDTPIINQPQTGILGVGAVVERLVPSRQDGELR 324
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPAT 640
+ +R M Y++++YDHR++DG +A FL +K +E+ T
Sbjct: 325 IDVRSMAYLSISYDHRIVDGADAARFLTTVKARLENGFT 363
>UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 414
Score = 160 bits (389), Expect = 3e-38
Identities = 88/211 (41%), Positives = 129/211 (61%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA++++ + NT E+ M I+ R+ L++ K+ K+ L + +KAA A+
Sbjct: 200 IAEKMQKSINTAPHFYVTMEVKMREILKLRET-LNSKLKEDEAKISLNTLLMKAAGIAIK 258
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
D P+ N+ +EE +II R+ ++I +AVA +GL+VPVIR V +I L +KAR
Sbjct: 259 DYPIFNSYVEEGQIILRNEINIGLAVALDEGLIVPVIREVDKKGLKEIAREEKALIQKAR 318
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKLT +E GG+FTISN G+F + IINPP+ AIL + I E P+ GQ+ I P+
Sbjct: 319 EGKLTPDEYTGGSFTISNLGMFDVVRFAAIINPPEVAILAVGKIREIPVVEEGQIEIEPI 378
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
M + L+ DHR+IDG A FLR+IKE +EDP
Sbjct: 379 MEMTLSSDHRVIDGALAAKFLRRIKEILEDP 409
>UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamideacetyltransferase; n=2;
Planctomycetaceae|Rep: Pyruvate dehydrogenase, E2
component, dihydrolipoamideacetyltransferase -
Blastopirellula marina DSM 3645
Length = 472
Score = 160 bits (388), Expect = 4e-38
Identities = 84/217 (38%), Positives = 133/217 (61%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA ++ + T +T F++ D++ + A R++ D + +KL MS VKA A AL
Sbjct: 254 IANQMVMSWTTAPRVTNFDDADVTALEALRQQSKDDYASA-GVKLTSMSFLVKAVALALR 312
Query: 182 DQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P +NA+I E N+++Y++YV++ +AV + +GLVVP IRN + +I + LA
Sbjct: 313 NNPAINALIDMENNQVVYKEYVNVGIAVDSERGLVVPNIRNADRLAIPEIARDVQKLAAD 372
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
R G +++++ GGTFTISN G G TPIIN P+ AIL + + P+ +N Q+V R
Sbjct: 373 VRGGTFSMDQIRGGTFTISNLGAIGGTYSTPIINVPEVAILLVGRSRKLPVVVNDQIVPR 432
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MM ++L+YDHRL+DG A FL +IK +E P+ ++
Sbjct: 433 MMMPLSLSYDHRLVDGATAARFLNEIKSYLEAPSRLL 469
>UniRef50_P37942 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=37; Bacillales|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Bacillus subtilis
Length = 424
Score = 160 bits (388), Expect = 4e-38
Identities = 83/210 (39%), Positives = 128/210 (60%), Gaps = 1/210 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA +K ++ T E+D+++++A+R D+F K L + FVKA A AL
Sbjct: 206 IASNMKRSKTEIPHAWTMMEVDVTNMVAYRNSIKDSFKKTEGFNLTFFAFFVKAVAQALK 265
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P +N++ ++II + ++IS+AVAT L VPVI+N T I I GLA+K R
Sbjct: 266 EFPQMNSMWAGDKIIQKKDINISIAVATEDSLFVPVIKNADEKTIKGIAKDITGLAKKVR 325
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRP 538
GKLT ++M GGTFT++N G FGS+ IIN PQ+AIL + I +RP+ + NG + +R
Sbjct: 326 DGKLTADDMQGGTFTVNNTGSFGSVQSMGIINYPQAAILQVESIVKRPVVMDNGMIAVRD 385
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
M+ + L+ DHR++DG FL ++K+ +E
Sbjct: 386 MVNLCLSLDHRVLDGLVCGRFLGRVKQILE 415
>UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Tropheryma whipplei|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 461
Score = 157 bits (380), Expect = 3e-37
Identities = 83/214 (38%), Positives = 130/214 (60%), Gaps = 5/214 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+R + A L+T E+D++ I+ +R + F + + L ++ + A AL
Sbjct: 242 IAERAVHSMQNTAQLSTVIEVDLTRIVDYRNSIKEKFKEAEGVNLTVLPFIINATVQALR 301
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
PV+N+ I +++I++ DY +IS+AV T +GL+ PVI+N +MT A ++ LA +AR
Sbjct: 302 KYPVINSHIVDDQIVFPDYENISLAVDTERGLLTPVIKNAGDMTVAQFAKSVFDLARRAR 361
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQ----V 526
KL+ +E+ GGTFT++N G G+L TP++ PQ AILG+ I RP I L+ Q +
Sbjct: 362 NNKLSPDELTGGTFTVTNTGSRGALFDTPVVFLPQLAILGIGAIARRPVIVLDAQGNECI 421
Query: 527 VIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
IR + + AL+YDHR+IDG +A FL IK +E
Sbjct: 422 SIRSVAFFALSYDHRVIDGADAARFLGYIKSLLE 455
>UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 431
Score = 157 bits (380), Expect = 3e-37
Identities = 83/217 (38%), Positives = 129/217 (59%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+++ + T +T +E+D++ ++ RK +L + K IKL + +KA AL
Sbjct: 212 IAEKMVKSAYTAPHVTGMDEVDVTKLVEIRK-NLASELAKEQIKLTYLPFIIKAVTRALK 270
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P+ NA ++E NEI+ + I +A AT GLVVPVIR+ + ++ + IA L+EK
Sbjct: 271 QYPMFNASLDEETNEIVLKKRYHIGIATATKAGLVVPVIRDADQKSIRELAIEIAELSEK 330
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
A L +EE+ G TFTI++ G G TPIIN P+ AI G H I RP+ + ++VIR
Sbjct: 331 AHRQALRLEELQGSTFTITSTGAGGGWFATPIINYPEVAIFGAHAIKRRPVVVGDEIVIR 390
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MM ++LT+DHR+IDG A F+R + +E+P ++
Sbjct: 391 DMMGMSLTFDHRVIDGEPAGRFMRTVAHYLENPEVLL 427
>UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=2; Bacteroidetes|Rep:
2-oxo acid dehydrogenases acyltransferase (Catalytic
domain) protein - Algoriphagus sp. PR1
Length = 432
Score = 157 bits (380), Expect = 3e-37
Identities = 78/215 (36%), Positives = 137/215 (63%), Gaps = 5/215 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQR+ D++ T+A +T+F E DM++I+ +R+K+ + +K + F++A A A+
Sbjct: 211 IAQRMVDSKKTSAHVTSFVEADMTNIVLWREKNKQAYREKFGESITYTPFFIEAIAKAIR 270
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKA 358
D P++N I+ ++II + ++I +AVA P G L+VPVIR + I + LA +A
Sbjct: 271 DFPMINISIDGDKIIKKKDINIGMAVALPSGNLIVPVIRKADQLNLVGISKQVNDLANRA 330
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL---NGQVV 529
R KL +++ GGT+T+SN G FG++MGTPII PQ AI+ + I ++P + G V+
Sbjct: 331 RNNKLNADDLSGGTYTVSNVGSFGNVMGTPIIMQPQVAIMAVGAIVKKPAVVETPTGDVI 390
Query: 530 -IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
+R M+++ +YDHR++DG +F++++ + +E+
Sbjct: 391 AVRHKMFLSHSYDHRVVDGSLGGMFVKRVADYLEE 425
>UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2,
dihydrolipoamide acetyltransferase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E2, dihydrolipoamide acetyltransferase -
Uncultured methanogenic archaeon RC-I
Length = 428
Score = 155 bits (377), Expect = 8e-37
Identities = 81/216 (37%), Positives = 132/216 (61%), Gaps = 2/216 (0%)
Frame = +2
Query: 14 LKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPV 193
++ Q+T A +T F++ D++ + R++ +K +K+ ++ VKA + AL + PV
Sbjct: 215 MRSLQHT-AQVTVFDDADVTKLSELREQV--NGARKDGVKVSYLAFTVKAVSAALRNHPV 271
Query: 194 VNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTG 367
+NA I E+ EI+ + Y +I +A+ TP+GL+V +++ + I I L E A +G
Sbjct: 272 LNASIDDEKGEIVLKKYYNIGLAIDTPRGLMVAPVKDADRKSIVQISREIKELVELAESG 331
Query: 368 KLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMY 547
K+ +E++ G TFTI+N G G L TPIINPP+SAIL M I + P +G V +R +M
Sbjct: 332 KIGVEQLRGSTFTIANIGSIGGLFATPIINPPESAILEMQQIRDMPRVCDGNVCVRKVMN 391
Query: 548 IALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
++LT DHR+IDG E FL ++K +EDPA ++ +
Sbjct: 392 LSLTIDHRIIDGAEGQRFLNEVKGYLEDPAALLVNM 427
>UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase; n=4;
Geobacter|Rep: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase -
Geobacter sulfurreducens
Length = 392
Score = 155 bits (375), Expect = 1e-36
Identities = 80/216 (37%), Positives = 126/216 (58%), Gaps = 2/216 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + +Q A +T E D++ + R++ ++ L + F+KA +AL
Sbjct: 173 IARNVMTSQRNTAFVTGMEEADITELWHLREREQQA-VEQRGTHLTFLPFFIKAVQHALR 231
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P +NA I++ EII + + +AV TP GL+VPVIRNV + ++ + L K
Sbjct: 232 EHPYLNAAIDDVAGEIILKKHYHFGIAVETPDGLMVPVIRNVDAKSIIELASELQELGRK 291
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR +T++EM G TFT++N G FG + TP+IN P AILG I +RP GQ+V+R
Sbjct: 292 ARERTITLDEMRGSTFTLTNFGHFGGVFATPVINWPDVAILGFGRIADRPWVHAGQIVVR 351
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATI 643
++ ++LT+DHR+ DG +A FL K+ +EDPA +
Sbjct: 352 TILPLSLTFDHRVTDGADAAQFLSKVVRYLEDPALL 387
>UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1;
Symbiobacterium thermophilum|Rep: Pyruvate dehydrogenase
E2 - Symbiobacterium thermophilum
Length = 450
Score = 154 bits (373), Expect = 2e-36
Identities = 86/217 (39%), Positives = 126/217 (58%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+R+ ++ T +TT E+DM+ +MAFR + + +K IKL M +KA AL
Sbjct: 231 IAERMVKSKYTAPHVTTVEEVDMTELMAFRAQAKELAARK-GIKLSFMPFIIKAVVAALR 289
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P +NA I++ EI+ I A+ T GL+VPVI++ I + L +
Sbjct: 290 EFPYLNASIDDEAQEIVLHKRYHIGFALDTDAGLLVPVIKDADRKPVFAIAQEMNDLIAR 349
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
R GKL +EM G TFTISN G G L TP+IN P+ AILG+ RP+ +G++VIR
Sbjct: 350 GREGKLAPDEMRGSTFTISNQGSIGGLFFTPVINYPEVAILGIGKTQPRPVVRDGEIVIR 409
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M ++AL++DHRLIDG A FL ++ E + DP ++
Sbjct: 410 QMAHLALSFDHRLIDGGMATRFLNRLAELLSDPTLLM 446
>UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=1; Salinibacter ruber DSM
13855|Rep: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein - Salinibacter ruber (strain
DSM 13855)
Length = 639
Score = 154 bits (373), Expect = 2e-36
Identities = 81/214 (37%), Positives = 131/214 (61%), Gaps = 6/214 (2%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A+ + ++ T+A +T+F E D++ ++ R+ + + F ++ +KL FVKAA AL +
Sbjct: 417 AEHMVRSKATSAHVTSFAEADVTGLVQLREANKEAFREREGVKLTYTPFFVKAAVEALRE 476
Query: 185 QPVVNAVIEENEIIYRDYVDISVAVATP-KGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P++NA +E ++I+ + + +AVA KGL+ PVIRN + + + A +AE+AR
Sbjct: 477 HPLLNASVEGDKIVIKHDFHVGIAVAIGNKGLLAPVIRNAGDYNVSGLARKAANVAERAR 536
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPI-----ALNGQV 526
+L +E+ GGTFT++N G GSLMGTPIIN PQ IL I +RP+ L +
Sbjct: 537 NKELQPDELQGGTFTVTNIGSLGSLMGTPIINQPQVGILATGAIQKRPVVVENDGLGDAI 596
Query: 527 VIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
+R MMY++L+YDHR+IDG FL+++ +E
Sbjct: 597 SVRHMMYLSLSYDHRIIDGAMGSSFLQRVVTELE 630
>UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=2; Bacilli|Rep: Branched-chain
alpha-keto acid dehydrogenase E2 - Symbiobacterium
thermophilum
Length = 459
Score = 153 bits (372), Expect = 3e-36
Identities = 79/217 (36%), Positives = 130/217 (59%), Gaps = 3/217 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA ++ A++ T ++D+++++ R++ F + L + F+KA +L
Sbjct: 240 IAAKMVQAKHEAPHAWTMMQVDVTNLVKLREQAGPEFRARTGRPLSYVPFFIKAVVESLR 299
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P++N+ +EI+ R ++ISVAVAT L VPVI++ ++ A + +A LAE+AR
Sbjct: 300 EYPILNSQWNGDEIVIRQDINISVAVATEDALAVPVIKHADRLSIAGLNEAVADLAERAR 359
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRP 538
G+LT++++ GGTFT++N G FGS + PIIN PQ+AIL I + P+ L N + IR
Sbjct: 360 AGRLTLDDVTGGTFTVNNTGAFGSFLSAPIINYPQAAILSFEKITKMPVVLENDAIAIRS 419
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVED--PATI 643
MM I L+ DHR++DG FL+ +K +E P T+
Sbjct: 420 MMNICLSLDHRILDGLVCGRFLQAVKRRLESYGPGTV 456
>UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Microscilla marina ATCC 23134
Length = 454
Score = 153 bits (372), Expect = 3e-36
Identities = 83/214 (38%), Positives = 130/214 (60%), Gaps = 5/214 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQR+ D++ + +TTF E D+++I+ +R K F +KH K+ F++A A L
Sbjct: 233 IAQRMVDSKRISPHVTTFVEADVTNIVMWRNKVKKEFQQKHGEKITFTPIFIEAIAKTLG 292
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKA 358
D P+VN+ IE II + ++I +A A P G L+VPVI+N M + + LA +A
Sbjct: 293 DFPLVNSSIEGENIIVKKDINIGMATALPSGNLIVPVIKNADQMNLLGLAKRVNDLANRA 352
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL---NGQVV 529
R KL +E+ GGT+T+SN G FG+ MGTPI+ PQ IL + I ++P+ + G V+
Sbjct: 353 RNNKLNPDELSGGTYTMSNIGGFGNEMGTPILVQPQVGILAIGAIKKKPVVIETPTGDVI 412
Query: 530 -IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
IR MM+++ YDHR++DG F+R++ + +E
Sbjct: 413 GIRHMMFMSHAYDHRIVDGALGGGFVRRVADYLE 446
>UniRef50_Q8R9E5 Cluster: Dihydrolipoamide acyltransferases; n=3;
Bacteria|Rep: Dihydrolipoamide acyltransferases -
Thermoanaerobacter tengcongensis
Length = 219
Score = 153 bits (370), Expect = 6e-36
Identities = 81/215 (37%), Positives = 130/215 (60%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I+QR+K + +T ++D++ ++ R + K K KA AL
Sbjct: 8 ISQRMKKSWTEIPHVTEDIKVDVTELVNLR----ENLNKSGEHKFTYTDLIAKACVIALK 63
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
PV+N IE +EII +++ +AVA GL+VPV++N +N + ++ I L+EKAR
Sbjct: 64 KNPVLNWSIEGDEIIKNPNINLGIAVALEDGLIVPVVKNAENKSLLELSKEIKELSEKAR 123
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KLT +E+ GGTFTI+N G++ TPIINPP+SAILG++ I++ P+ + +VIR
Sbjct: 124 ENKLTPDEITGGTFTITNLGMYEIDSFTPIINPPESAILGVNKIYKEPVVIEDNIVIRHT 183
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M ++L++DHRLIDG A FL +K+ +E+P +++
Sbjct: 184 MKLSLSFDHRLIDGATAAKFLLDLKKILENPVSML 218
>UniRef50_A1UIB1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=4; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Mycobacterium sp. (strain KMS)
Length = 629
Score = 152 bits (369), Expect = 7e-36
Identities = 84/216 (38%), Positives = 128/216 (59%), Gaps = 7/216 (3%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A++ +++ A LT +E+DM+ I+A R K + F ++ + L + +A +AL
Sbjct: 405 AKKTRESLQATAQLTQTHEVDMTKIVALRAKAKNDFAEREGVNLTYLPFIARAVIDALKQ 464
Query: 185 QPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P VNA E+ EI Y D + AV T +GL+ PVI+N +++ A + IA +A +A
Sbjct: 465 HPNVNASYNEDTKEITYYDAEHLGFAVDTDQGLLSPVIKNAGDLSLAGLARAIADIAARA 524
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-----NGQ 523
R+G L +E+ GGTFTI+N G G+L TPI+ PPQ+A+LG I +RP + N
Sbjct: 525 RSGDLKPDELSGGTFTITNIGSQGALFDTPILVPPQAAMLGTGAIVKRPRVIVDEFGNES 584
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
+ +R + Y+ LTYDHRLIDG +A FL IK +E+
Sbjct: 585 IGVRSICYLPLTYDHRLIDGADAGRFLTTIKRRLEE 620
>UniRef50_A5UTW4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Chloroflexi (class)|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Roseiflexus sp. RS-1
Length = 434
Score = 151 bits (366), Expect = 2e-35
Identities = 82/198 (41%), Positives = 120/198 (60%), Gaps = 4/198 (2%)
Frame = +2
Query: 47 TTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEII 226
TT E+DM ++A R+++ +F ++ I+L + + V+A A AL P +N ++ II
Sbjct: 233 TTVFEVDMGRVLAHRERYRSSF-EQQGIRLTVTAYIVQAVATALRRVPALNTRFTDDGII 291
Query: 227 YRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFT 406
+ I +AVA GL+VPV+R+ + A I + L E+AR +L +E +GGTFT
Sbjct: 292 TYRRIHIGIAVALDDGLIVPVLRDADEKSLAGIARALNDLTERARMRRLQPDETEGGTFT 351
Query: 407 ISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQ----VVIRPMMYIALTYDHRL 574
ISN GV GSL TPI+N QS ILG+ I +RP+ + Q +VIRPM Y++LT+DHR
Sbjct: 352 ISNHGVGGSLFATPILNRGQSGILGVGAIVKRPVVITHQGSDAIVIRPMCYLSLTFDHRA 411
Query: 575 IDGREAVLFLRKIKEGVE 628
DG A FL +KE +E
Sbjct: 412 CDGATADAFLAAVKETLE 429
>UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1;
Streptomyces coelicolor|Rep: Putative acyltransferase -
Streptomyces coelicolor
Length = 417
Score = 150 bits (364), Expect = 3e-35
Identities = 88/218 (40%), Positives = 128/218 (58%), Gaps = 6/218 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I LK A A LT+ E D++ +M R + D F + +KL M FVKAAA AL
Sbjct: 189 IGNNLKKALLEQAQLTSTVEADVTRLMRLRNRAKDGFLAREGLKLSPMPFFVKAAAQALK 248
Query: 182 DQPVVNAVIEENE--IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
PVVNA I E+E I Y D +I +AV T GL+ PV++ ++T A + + LA++
Sbjct: 249 AHPVVNARINEDEGTITYFDSENIGIAVDTEAGLMTPVVKAAGDLTVAGLARAVHDLADR 308
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP--IALNGQVV 529
AR G LT +++ G TFTISN G G+L T I+ P Q+AILG+ RP + + + V
Sbjct: 309 ARGGHLTPDDVSGATFTISNTGSRGALFDTVIVPPNQAAILGVGATVRRPGVVRVGDEEV 368
Query: 530 I--RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPA 637
I R +++++L+YDHRL+DG +A +L +K +E A
Sbjct: 369 IGVRDLVHLSLSYDHRLVDGADAARYLTAVKALLESAA 406
>UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Mycobacterium leprae|Rep: Dihydrolipoamide
succinyltransferase - Mycobacterium leprae
Length = 530
Score = 150 bits (363), Expect = 4e-35
Identities = 84/218 (38%), Positives = 126/218 (57%), Gaps = 7/218 (3%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A++ +++ A LT +E+DM+ I+ R K F ++ + L + KAA +AL
Sbjct: 306 AKKTRESLQATAQLTQTHEVDMAKIVGLRAKAKAAFAEREGVNLTFLPFIAKAAIDALKI 365
Query: 185 QPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P +NA E+ EI Y D + A+ T KGL+ PVI +++ A + I +A +A
Sbjct: 366 HPNINASYNEDTKEITYYDAEHLGFAIDTDKGLLSPVIHYAGDLSLAGLARAIVDIAARA 425
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-----NGQ 523
R+G L EE+ GGTFTI+N G G+L TPI+ PPQ+A+LG+ I +RP + N
Sbjct: 426 RSGNLKPEELSGGTFTITNIGSQGALFDTPILVPPQAAMLGIGAIVKRPRVVIDASGNES 485
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPA 637
+ +R + Y+ LTYDHRLIDG +A FL IK +E+ A
Sbjct: 486 IGVRAICYLPLTYDHRLIDGADAGRFLTTIKHRLEEGA 523
>UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC
14580|Rep: AcoC - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 377
Score = 149 bits (360), Expect = 9e-35
Identities = 72/215 (33%), Positives = 130/215 (60%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA R+ ++ +A LT + D++ + +K+ +T ++ KL + +AA +L+
Sbjct: 162 IAARMTESLQNSAQLTITMKADITKLTVLQKQLNETAQSRYDTKLTITDFAARAAVFSLL 221
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
D P +N+V ++ + ++V + VA A +GL VPVIR+ + + ++ I A+KAR
Sbjct: 222 DHPAMNSVYQDGRLATFEHVHLGVAAALDEGLAVPVIRHAERLPLIELAKKIKWYAKKAR 281
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G+L +E++G TFTI+N G +G TPI+NPP++ ILG+ ++ P+ +G++ +
Sbjct: 282 EGRLLHDEIEGSTFTITNLGAYGVEHFTPILNPPETGILGVGQMYSAPVYQDGELTKGAI 341
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ ++LT+DHR +DG A FL +K +EDPA+I+
Sbjct: 342 LPLSLTFDHRALDGAPAAAFLSDVKNYLEDPASIL 376
>UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=12; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Mycobacterium bovis
Length = 553
Score = 149 bits (360), Expect = 9e-35
Identities = 83/218 (38%), Positives = 126/218 (57%), Gaps = 7/218 (3%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A + +++ A LT +E+DM+ I+ R + F ++ + L + F KA +AL
Sbjct: 329 ANKTRESLQATAQLTQTHEVDMTKIVGLRARAKAAFAEREGVNLTFLPFFAKAVIDALKI 388
Query: 185 QPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P +NA E+ EI Y D + AV T +GL+ PVI + +++ A + IA +A +A
Sbjct: 389 HPNINASYNEDTKEITYYDAEHLGFAVDTEQGLLSPVIHDAGDLSLAGLARAIADIAARA 448
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-----NGQ 523
R+G L +E+ GGTFTI+N G G+L TPI+ PPQ+A+LG I +RP + N
Sbjct: 449 RSGNLKPDELSGGTFTITNIGSQGALFDTPILVPPQAAMLGTGAIVKRPRVVVDASGNES 508
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPA 637
+ +R + Y+ LTYDHRLIDG +A FL IK +E+ A
Sbjct: 509 IGVRSVCYLPLTYDHRLIDGADAGRFLTTIKHRLEEGA 546
>UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase
complex E2 component; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to 2-oxoglutarate
dehydrogenase complex E2 component - Candidatus Kuenenia
stuttgartiensis
Length = 416
Score = 148 bits (359), Expect = 1e-34
Identities = 79/211 (37%), Positives = 132/211 (62%), Gaps = 3/211 (1%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVK-AAANALM 181
A+R+ ++ T A++TT E+DM+ + +R+ + + K+ I L + PF+ A AL
Sbjct: 186 AERMALSRQTAALVTTVFEVDMTPVTKYRELNREAM-KREGIHLTYL-PFIAFAVVQALK 243
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ +N+ +N I+ ++Y+++ +AVA GLVVPVI++ + I +A AR
Sbjct: 244 EHVALNSSWTDNGILQKNYINLGIAVALEDGLVVPVIKDADKKDMFQLAREIQEIAVNAR 303
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN--GQVVIR 535
+ KL +++ GGTFTI+N GV GSL GTP+I PQSAILG+ + +RP+ L + +R
Sbjct: 304 SKKLKPDDVRGGTFTITNYGVNGSLFGTPLILQPQSAILGVGAVVKRPVILGDADAIAVR 363
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
M+Y++L++DHR++DG A FL K+K+ +E
Sbjct: 364 SMVYLSLSFDHRVMDGAHADAFLHKVKDILE 394
>UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=1; Croceibacter atlanticus HTCC2559|Rep: Lipoamide
acyltransferase component of branched-chain
alpha-ketoacid dehydrogenase complex - Croceibacter
atlanticus HTCC2559
Length = 480
Score = 148 bits (359), Expect = 1e-34
Identities = 77/214 (35%), Positives = 130/214 (60%), Gaps = 5/214 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA + +++T+ +T + E DM+ I+ +R + F + + KL FV+A ANA+
Sbjct: 259 IADHMVYSKHTSPHVTAYVEADMTDIVNWRNANKVKFQETYGEKLTFTPLFVEAVANAIT 318
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKA 358
+ P++N ++ II ++++++ +A A P G L+VPV+++ ++ + +A A
Sbjct: 319 EFPMINVSVDGRNIIVKEHINVGMATALPSGNLIVPVVKDADKKNLQELATDVNRMANLA 378
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL----NGQV 526
R KL +++ G TFTISN G FGS+MGTPIIN P++AIL I +RP + N +
Sbjct: 379 RENKLGGDDIKGSTFTISNVGTFGSVMGTPIINQPEAAILATGIIKKRPEVITKDGNDTI 438
Query: 527 VIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
IR MMY++L++DHR++DG FL+KI + +E
Sbjct: 439 EIRSMMYLSLSFDHRIVDGFLGGSFLKKIADNLE 472
>UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2
component; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase complex, E2 component - Aeropyrum pernix
Length = 412
Score = 147 bits (356), Expect = 3e-34
Identities = 79/200 (39%), Positives = 126/200 (63%), Gaps = 3/200 (1%)
Frame = +2
Query: 59 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFV-KAAANALMDQPVVNAVIEEN--EIIY 229
E+D + + R+ L ++ ++L + PFV KA A A+ P+VN+ +E EI+
Sbjct: 209 EVDFTELSKLREA-LKRDAEEKGVRLTYL-PFVFKAVAKAIRKYPLVNSEFDEEKMEIVV 266
Query: 230 RDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTI 409
+ V+I AV TP GLVVPV++NV+ I IA L KAR +L++EE+ G TFTI
Sbjct: 267 KKAVNIGFAVDTPHGLVVPVVKNVEKKGLFAIAREIADLTAKAREMRLSLEEVSGATFTI 326
Query: 410 SNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGRE 589
+N G GS++G P+I PP AILG+H + ERP+ ++G++ R + +++L++DHR ++G
Sbjct: 327 TNVGSIGSVIGFPVIYPPNVAILGVHRLVERPVYVDGELKPRKIGFVSLSFDHRALEGAY 386
Query: 590 AVLFLRKIKEGVEDPATIVA 649
A FL ++K +E+PA + A
Sbjct: 387 ATRFLMEVKRLLENPALLFA 406
>UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=80; Bacilli|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Bacillus subtilis
Length = 442
Score = 147 bits (355), Expect = 4e-34
Identities = 82/217 (37%), Positives = 131/217 (60%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + ++++T +T +E+D+++++A RK+ + IKL + VKA +AL
Sbjct: 224 IAKAMVNSKHTAPHVTLMDEVDVTNLVAHRKQFKQVAADQ-GIKLTYLPYVVKALTSALK 282
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
PV+N I++ +E+I + Y +I +A T KGL+VPV++N + +I I GLA K
Sbjct: 283 KFPVLNTSIDDKTDEVIQKHYFNIGIAADTEKGLLVPVVKNADRKSVFEISDEINGLATK 342
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR GKL EM G + TI+N G G TP+IN P+ AILG+ I E+ I +G++V
Sbjct: 343 AREGKLAPAEMKGASCTITNIGSAGGQWFTPVINHPEVAILGIGRIAEKAIVRDGEIVAA 402
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
P++ ++L++DHR+IDG A L IK + DP I+
Sbjct: 403 PVLALSLSFDHRMIDGATAQNALNHIKRLLNDPQLIL 439
>UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
halodurans|Rep: Pyruvate dehydrogenase E2 - Bacillus
halodurans
Length = 414
Score = 146 bits (354), Expect = 5e-34
Identities = 82/220 (37%), Positives = 131/220 (59%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+++ + T +T +EI+M + R++ L ++++ IKL + F+KA +AL
Sbjct: 195 IAEKMIKSVATIPHVTHVDEIEMDALKELREQ-LKHYSEQKGIKLTFLPFFIKAIVSALK 253
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ NA I+E NEI+ + I +A T KGL+VPVI+N + ++ I L+ +
Sbjct: 254 EFEYFNASIDEETNEIVLKKDYHIGIATDTEKGLIVPVIQNADQKSLLELAGEITQLSTQ 313
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR G L +++M G TFTISN G G L TPIIN P+ AIL +H + R + + VI+
Sbjct: 314 ARKGTLNVQQMTGSTFTISNVGPIGGLHATPIINYPEVAILALHKMEPRNVVREWESVIK 373
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
MM ++L++DHRL+DG AV F ++KE +E+P ++ L
Sbjct: 374 LMMNMSLSFDHRLVDGATAVRFTNRMKELIENPNLLLMEL 413
>UniRef50_Q67RX4 Cluster: Putative uncharacterized protein; n=1;
Symbiobacterium thermophilum|Rep: Putative
uncharacterized protein - Symbiobacterium thermophilum
Length = 262
Score = 146 bits (354), Expect = 5e-34
Identities = 78/211 (36%), Positives = 122/211 (57%), Gaps = 3/211 (1%)
Frame = +2
Query: 14 LKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKH-SIKLGLMSPFVKAAANALMDQP 190
L+ AQ T A +T E+D + +++ R+ L ++H I+L + F A AL P
Sbjct: 52 LEQAQRTTAPVTVVAEVDATGLISVRES-LKPLAERHLGIRLTYLPFFAAATVRALKAWP 110
Query: 191 VVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGK 370
++NA++ + Y+++ +A A P G+++PV+ + M + D+ I +KAR G
Sbjct: 111 IMNAMLTPQGFVIPRYINLGIATAVPGGVLLPVVPGAERMGFWDLARAIHLQTQKARAGL 170
Query: 371 LTIEEMDGGTFTISNGGVFG-SLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPMM 544
L+ E+ G TF I+N G +G +L GTPII PP IL I +RP+ + + Q+ IRPMM
Sbjct: 171 LSPHELSGHTFVITNTGRYGATLFGTPIIQPPNVGILAFEAIQKRPVVVGDDQLAIRPMM 230
Query: 545 YIALTYDHRLIDGREAVLFLRKIKEGVEDPA 637
Y+ALT DHR +DG E + FL +KE +E A
Sbjct: 231 YLALTADHRAVDGAEMIGFLATVKEALEQVA 261
>UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Acidobacteria|Rep: Dihydrolipoamide
S-succinyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 555
Score = 146 bits (354), Expect = 5e-34
Identities = 74/215 (34%), Positives = 130/215 (60%), Gaps = 5/215 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA + ++ T+A + E+D + I+ R+K+ ++F +K +KL + +A A+AL
Sbjct: 335 IADHMVMSKRTSAHVHGVFEVDFTKIVKLREKNKNSFQEKTGLKLTYTPFYARAVAHALR 394
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P++NA +E I Y+ +++ +AVA GL+VPV++ +++ ++ I L E+AR
Sbjct: 395 AWPIINASVEGENIHYKKDINLGIAVALDWGLIVPVVKQADGLSFVGLQRAITDLGERAR 454
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-----NGQV 526
KL E++ GGTFTI+N G+FG+ G PII+ PQ AILG+ I + P+ + N +
Sbjct: 455 AKKLKPEDVQGGTFTITNPGIFGAKFGMPIISQPQLAILGIGAITKVPMVVTDKDGNDSI 514
Query: 527 VIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
IR +I++ YDHR+IDG A F+ +++ +++
Sbjct: 515 AIRSRCHISIGYDHRVIDGAVADQFMVVVRDYLQN 549
>UniRef50_Q18CC2 Cluster: E2 component of acetoin dehydrogenase
enzyme system; n=2; Clostridium difficile|Rep: E2
component of acetoin dehydrogenase enzyme system -
Clostridium difficile (strain 630)
Length = 348
Score = 145 bits (352), Expect = 8e-34
Identities = 80/217 (36%), Positives = 131/217 (60%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFN-EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANAL 178
+A+R+ ++ +A + TFN E+D + + R K +DT + +KL + V A + L
Sbjct: 133 VAKRMSESY-FSAPVFTFNIEVDATELKVLRAKLIDTVKESTGVKLTMTDLIVMAVSKIL 191
Query: 179 MDQPVVNAVIEENEII-YRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ +N+ + I Y+D V+I++AV +GL VPV++N + +I LAEK
Sbjct: 192 PNHQALNSAWTDEGIFRYKD-VNIAIAVGLDEGLYVPVVKNANKKSLKEIAKESKELAEK 250
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
+TGKL + +G TFTISN G++G TPIIN P SAILG+ ++ + +NG+ I+
Sbjct: 251 VKTGKLMPADQEGNTFTISNVGMYGITTFTPIINMPSSAILGVGATQDKFVPVNGEAKIK 310
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
P+M ++LT DHR+IDG A FL+ +KE +E+P +++
Sbjct: 311 PIMNLSLTSDHRVIDGTVAAKFLKDLKELLENPLSML 347
>UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=8; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Bacteroides thetaiotaomicron
Length = 456
Score = 145 bits (351), Expect = 1e-33
Identities = 76/215 (35%), Positives = 128/215 (59%), Gaps = 5/215 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA + ++ + +T E+D++ ++ +R+K+ D F ++ +KL M +A A AL
Sbjct: 239 IADHMVMSKKVSPHVTNVVEVDVTKLVRWREKNKDAFFRREGVKLTYMPVITEAVAKALA 298
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKA 358
P VN ++ I+++ +++I +AV+ G L+VPV+ + ++ + + I LA KA
Sbjct: 299 AYPQVNVSVDGYNILFKKHINIGIAVSLNDGNLIVPVVHDADHLNLNGLAVAIDSLALKA 358
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL----NGQV 526
R KL +++DGGTFTI+N G F SL GTP+IN PQ AILG+ I ++P + +
Sbjct: 359 RDNKLMPDDIDGGTFTITNFGTFKSLFGTPVINQPQVAILGVGYIEKKPAVIETPEGDTI 418
Query: 527 VIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
IR MY++L+YDHR++DG FL I + +E+
Sbjct: 419 AIRHKMYLSLSYDHRVVDGMLGGNFLHFIADYLEN 453
>UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E2
component; n=2; Alteromonadales|Rep: Apha keto acid
dehydrogenase complex, E2 component - Idiomarina baltica
OS145
Length = 515
Score = 144 bits (350), Expect = 1e-33
Identities = 78/221 (35%), Positives = 137/221 (61%), Gaps = 3/221 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+++ ++ +T T +E D+++++A R+K + + K+ ++L +M F+KA + AL
Sbjct: 295 MAKQMMNSVSTIPHFTYSDEFDLTNLIALREKLKEQY-KEQGVRLTVMPFFIKALSLALK 353
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P++NA + ++ E+ Y D +I +AV T GL+VP ++ VQN + D+ + L +
Sbjct: 354 EFPIMNAQVNDDCTEVTYFDDHNIGMAVDTKIGLLVPNVKQVQNKSIIDVANEVTRLTQA 413
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVI 532
AR GK+ +M GGT +ISN GV G + TPIIN P++AI+ + + E P NGQVV
Sbjct: 414 AREGKVPQADMKGGTISISNIGVIGGTVATPIINKPEAAIVALGKVQELPRFDANGQVVA 473
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
R MM ++ + DHR+IDG F ++ +E +EDP +++ +
Sbjct: 474 RKMMTVSWSGDHRIIDGGTIARFNKRWQEFLEDPTSMLVNM 514
>UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=4; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-ketoacid dehydrogenase
complex - Dokdonia donghaensis MED134
Length = 439
Score = 144 bits (349), Expect = 2e-33
Identities = 78/214 (36%), Positives = 128/214 (59%), Gaps = 5/214 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA + +++T+ +T + E D++ ++ +R + F +KH +L FV+A A A+
Sbjct: 218 IADHMVYSKHTSPHVTAYVEADLTEMVQWRNDNKVAFQEKHGERLTFTPLFVEAVAKAVE 277
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKA 358
+ P++N ++ II ++ ++I +A A P G L+VPV++N +I + L+ A
Sbjct: 278 EFPMINVSVDGKNIIVKEDINIGMATALPSGNLIVPVVKNANQRNLVEIAAEVNRLSSLA 337
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL---NGQVV 529
R KL +++ G TFTISN G FGS+MGTPIIN P++AIL I +R + G +
Sbjct: 338 RENKLGGDDVKGSTFTISNVGTFGSVMGTPIINQPEAAILATGIIKKRAEVMERPEGDTI 397
Query: 530 -IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
IR MMY++L++DHR++DG FLRKI + +E
Sbjct: 398 EIRQMMYLSLSFDHRIVDGYLGGSFLRKIADHLE 431
>UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system;
n=13; Bacillus|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system -
Bacillus subtilis
Length = 398
Score = 144 bits (349), Expect = 2e-33
Identities = 73/215 (33%), Positives = 128/215 (59%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA R++++ +A LT + D++ + +K+ T +++ KL + +AA AL
Sbjct: 183 IAARMQESLANSAQLTITMKADITKLATLQKQLSPTAEERYGTKLTITHFVSRAAVLALQ 242
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
PV+N+ + II +V + +AVA GLVVPVIR+ + ++ ++ +I+ A+KAR
Sbjct: 243 AHPVLNSFYQNERIITHPHVHLGMAVALENGLVVPVIRHAEKLSLIELAQSISENAKKAR 302
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G+ EE+ G TF+I+N G FG TPI+NPP++ ILG+ ++ P+ ++V +
Sbjct: 303 EGRAGSEELQGSTFSITNLGAFGVEHFTPILNPPETGILGIGASYDTPVYQGEEIVRSTI 362
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ ++LT+DHR DG A FL+ +K +E+PA ++
Sbjct: 363 LPLSLTFDHRACDGAPAAAFLKAMKTYLEEPAALI 397
>UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 422
Score = 143 bits (346), Expect = 5e-33
Identities = 74/217 (34%), Positives = 124/217 (57%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA R++ + T A LT E+++S ++ R + L ++ K+ F+KA A AL
Sbjct: 207 IADRMQQSLQTTAQLTDVREVEVSALVELRNR-LAAKAERIGFKVSFTDLFLKATALALR 265
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P +N ++ + II D+V + +AV+ P GL+VPV+R+ ++ I A AR
Sbjct: 266 EVPELNVTVQADRIIEHDHVHLGMAVSVPDGLIVPVVRDADQLSLRAIHQRSEEAALAAR 325
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
K+T ++ GGTFT++N G +GS GTP++N PQ AIL I +RP+ +G+V +
Sbjct: 326 ERKVTAADLTGGTFTVTNIGSYGSHFGTPVLNLPQVAILATGAILDRPVVRDGEVRAGKV 385
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAG 652
++++LT DHR+IDG A F + + +P ++ G
Sbjct: 386 VHLSLTVDHRIIDGELAGRFHNTMAALLAEPDRLLVG 422
>UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;
n=2; Deinococcus|Rep: 2-oxo acid dehydrogenase, E2
component - Deinococcus radiodurans
Length = 525
Score = 142 bits (345), Expect = 6e-33
Identities = 75/214 (35%), Positives = 126/214 (58%), Gaps = 3/214 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA +++ + T +E++++ ++ FR++ D K +KL + KA AL
Sbjct: 305 IANQMQASHLYTVRTLTVDEVNLTKLVEFRQRVKDE-AKAADVKLSYLPFIFKAITVALK 363
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P +N +E EI+ + Y ++ +AVAT GL VPVIR+V + D+ + LA +
Sbjct: 364 KYPSLNTSFDEATQEIVQKSYYNLGMAVATEAGLTVPVIRDVDRKSIFDLARDVVDLAGR 423
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIA-LNGQVVI 532
A GKL+ +E+ G +F+++N G G+L PIIN P +AI+G+H I +RPI + + +
Sbjct: 424 ANAGKLSPDELTGSSFSVTNIGSIGALFSFPIINVPDAAIMGVHSIVKRPIVDEHDNITV 483
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
MMY++L++DHRLIDG EA F +++ +E+P
Sbjct: 484 AHMMYLSLSFDHRLIDGAEAARFCKEVIRLLENP 517
>UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=22; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas aeruginosa
Length = 428
Score = 142 bits (345), Expect = 6e-33
Identities = 78/216 (36%), Positives = 131/216 (60%), Gaps = 2/216 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQ+++DA+ + EID++ + A R HL+ KL L+ V+A AL
Sbjct: 211 IAQKMQDAKRRIPHFSYVEEIDVTDLEALRA-HLNQKWGGQRGKLTLLPFLVRAMVVALR 269
Query: 182 DQPVVNAVIE-ENEIIYR-DYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
D P +NA + E E++ R V + +A + GL+VPV+R+ ++ +A LAE
Sbjct: 270 DFPQLNARYDDEAEVVTRYGAVHVGIATQSDNGLMVPVLRHAESRDLWGNASEVARLAEA 329
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR+GK +E+ G T T+S+ GV G ++ TP+IN P+ AI+G++ I ERP+ + G +V+R
Sbjct: 330 ARSGKAQRQELSGSTITLSSLGVLGGIVSTPVINHPEVAIVGVNRIVERPMVVGGNIVVR 389
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATI 643
MM ++ ++DHR++DG +A F++ ++ +E PAT+
Sbjct: 390 KMMNLSSSFDHRVVDGMDAAAFIQAVRGLLEHPATL 425
>UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue
acetyltransferase component e2 of pyruvate dehydrogenase
protein; n=1; Spiroplasma citri|Rep: Putative
dihydrolipoyllysine-residue acetyltransferase component
e2 of pyruvate dehydrogenase protein - Spiroplasma citri
Length = 427
Score = 142 bits (343), Expect = 1e-32
Identities = 84/218 (38%), Positives = 127/218 (58%), Gaps = 3/218 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+++ ++ A T ID++ ++ R + L ++ +KL M F+KA A AL
Sbjct: 210 IAKQMTLSKTVIAEATLMKNIDVTKLIEIRAQ-LKGQAEQQGVKLTYMPFFMKACAIALK 268
Query: 182 DQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
D P++NA E+ EII++DY +I +A TP GL+VPV++ V + I I LA K
Sbjct: 269 DFPILNAAYDQEQQEIIFKDYYNIGMATDTPTGLMVPVVKGVDQLNIMQIAKMINDLATK 328
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVI 532
R KL +EM GTFTI+N G G TP+IN P+ AILG+ I + P I N ++ I
Sbjct: 329 TRERKLKPDEMKDGTFTITNFGSAGIEFATPVINFPEVAILGVGIIKKAPVINKNNEIEI 388
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
++ ++LT DHRLIDG + FL ++ E +E PA ++
Sbjct: 389 SSILPLSLTIDHRLIDGADGGRFLARVTELLESPALLL 426
>UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep:
Lin1411 protein - Listeria innocua
Length = 416
Score = 141 bits (341), Expect = 2e-32
Identities = 73/190 (38%), Positives = 115/190 (60%)
Frame = +2
Query: 59 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY 238
E+D + ++ +R D+F K+ L + F+KA A AL + P +N+ ++II
Sbjct: 217 EVDATGLVRYRNTVKDSFKKEEGYSLTYFAFFIKAVAQALKEFPQLNSTWAGDKIIEHAN 276
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
++IS+A+A L VPVI+N + I I+ LA KAR GKL+ +M+GGTFT+++
Sbjct: 277 INISIAIAAGDLLYVPVIKNADEKSIKGIAREISELAGKARNGKLSQADMEGGTFTVNST 336
Query: 419 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 598
G FGS+ IIN PQ+AIL + I +RP+ ++ + +R M+ + L+ DHR++DG A
Sbjct: 337 GSFGSVQSMGIINHPQAAILQVESIVKRPVIIDDMIAVRDMVNLCLSIDHRILDGLLAGK 396
Query: 599 FLRKIKEGVE 628
FL+ IK VE
Sbjct: 397 FLQAIKANVE 406
>UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;
n=2; Anaeromyxobacter|Rep: Dehydrogenase complex
catalytic domain - Anaeromyxobacter sp. Fw109-5
Length = 454
Score = 141 bits (341), Expect = 2e-32
Identities = 73/213 (34%), Positives = 120/213 (56%), Gaps = 2/213 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + ++ T A T + D++ + A K+ + K+ +KL + VKA AL
Sbjct: 235 IAENMARSKRTAAHFTFVEQCDVTEL-ARVKERMAVAAKEEGVKLTFLPFVVKAVVAALR 293
Query: 182 DQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P +NA + E E++ D+ +A AT GLVVPV+R + ++ I LA+
Sbjct: 294 KHPKLNATMDDERGELVLHRRYDVGIASATDAGLVVPVVRGADRRSLVELAREIERLAQD 353
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
A+ G+ E+M TFTI++ G G + TP++N P+ ILG+H I P+ +GQVV+R
Sbjct: 354 AKAGRARPEDMGRSTFTITSLGALGGMFATPVLNYPEVGILGVHRIRPTPVVRDGQVVVR 413
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+M++++T DHR++DG EA F ++ +EDP
Sbjct: 414 DVMHVSVTSDHRVVDGHEAAAFCYEVIRTLEDP 446
>UniRef50_Q98PG1 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=1;
Mycoplasma pulmonis|Rep: DIHYDROLIPOAMIDE
ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE
COMPLEX - Mycoplasma pulmonis
Length = 315
Score = 140 bits (340), Expect = 2e-32
Identities = 80/213 (37%), Positives = 120/213 (56%), Gaps = 2/213 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ +K++Q+ A ++ +EIDM+ + RK ++ IKL + +KA A A+
Sbjct: 97 IARAMKNSQDNVAYVSLVHEIDMTKLWDLRKSVVEKVKDLTGIKLTFLPFILKAIAIAIK 156
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
D + A +E E++Y D V++ VAV T GL+VPVI+N Q++ + I LA
Sbjct: 157 DFQIFGAKYDEKTEELVYPDTVNLGVAVDTDHGLMVPVIKNAQSLNLVEFSQEIIRLANL 216
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
ART + +M G TFTI+N G GSL GTP+IN P+ AI G+ I ++ NG V
Sbjct: 217 ARTKTIKPADMSGATFTITNYGSVGSLFGTPVINYPELAIAGVGAIVDKVYWKNGAAVPG 276
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+M+I + DHR IDG F+ K+K +E P
Sbjct: 277 KVMWITIAADHRWIDGATMGKFISKVKSLLEQP 309
>UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=3; Staphylococcus|Rep:
Branched-chain alpha-keto acid dehydrogenase E2 -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 442
Score = 140 bits (340), Expect = 2e-32
Identities = 70/190 (36%), Positives = 114/190 (60%)
Frame = +2
Query: 59 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY 238
E+D ++++ R H ++F + L + FVKA A AL P++N+ + EII
Sbjct: 243 EVDATNLVKTRNHHKNSFKENEGYNLTFFAFFVKAVAEALKSNPLLNSSWDGEEIILHKD 302
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
++IS+AVA L VPVI++ + I I LA KAR +L+ E+M GGTFT++N
Sbjct: 303 INISIAVADEDKLYVPVIKHADEKSIKGIAREINELALKARNKQLSQEDMSGGTFTVNNT 362
Query: 419 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 598
G FGS+ IIN PQ+AIL + I ++P+ ++ + IR M+ + ++ DHR++DG +
Sbjct: 363 GTFGSVSSMGIINHPQAAILQVESIVKKPVVIDDMIAIRSMVNLCISIDHRILDGVQTGR 422
Query: 599 FLRKIKEGVE 628
F+ ++KE +E
Sbjct: 423 FMSQVKERIE 432
>UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Thermoanaerobacter ethanolicus|Rep:
Biotin/lipoyl attachment:Catalytic domain of components
of various dehydrogenase complexes:E3 binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 382
Score = 140 bits (340), Expect = 2e-32
Identities = 76/215 (35%), Positives = 132/215 (61%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I+QR+K + + +T ++D++ ++ R+ +L+ + L++ KA A+
Sbjct: 171 ISQRMKKSWSEIPHVTEDIKVDVTELVNLRE-NLNHISDNKFTYTDLIA---KACVIAIK 226
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
PVVN IE II +++ +AVA GL+VPV++ + ++ I L+E+AR
Sbjct: 227 KNPVVNWSIEGEYIIKNSSINLGIAVALDNGLIVPVVKEADKKSLLELSKNIKELSERAR 286
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KLT +E+ G TFTI+N G++ TPIINPP+SAILG++ I++ P+ L+ +VIR +
Sbjct: 287 NNKLTPDEIIGSTFTITNLGMYEIDSFTPIINPPESAILGVNKIYKEPVVLDDNIVIRHI 346
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ ++L++DHRLIDG A FL +K+ +E+P +++
Sbjct: 347 IKLSLSFDHRLIDGATAAKFLLDLKKTLENPLSLL 381
>UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=1; Gramella forsetii KT0803|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Gramella forsetii
(strain KT0803)
Length = 507
Score = 140 bits (340), Expect = 2e-32
Identities = 89/223 (39%), Positives = 125/223 (56%), Gaps = 9/223 (4%)
Frame = +2
Query: 11 RLKDAQNTNAMLTT------FNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAAN 172
R A+NT+A +T F+E D+S I ++ ++ +K L + + K +A+
Sbjct: 288 RKATAKNTSAAWSTIPHVFQFDEADISDI----EERMEKLQEKADGNLTITAILAKISAS 343
Query: 173 ALMDQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGL 346
AL P NA I E E+I + YV+I +AV T KGL+VPV+RN T +I I L
Sbjct: 344 ALRQFPKFNASIDMENEEMILKKYVNIGIAVDTEKGLLVPVVRNADQKTIIEISTEITEL 403
Query: 347 AEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQV 526
AEKAR KL+ EEM GG FTISN G G TPI+ PQ AILG+ ++P+ +
Sbjct: 404 AEKARNVKLSAEEMKGGNFTISNLGGIGGTNFTPIVYHPQVAILGVSRAKKQPVYKDDDT 463
Query: 527 V-IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAG 652
R ++ ++L+YDHR+IDG E V FL I +EDP + G
Sbjct: 464 FEARDILPLSLSYDHRIIDGAEGVRFLHWISRALEDPYEALLG 506
>UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component; n=4;
Deinococci|Rep: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component -
Deinococcus radiodurans
Length = 617
Score = 140 bits (339), Expect = 3e-32
Identities = 87/212 (41%), Positives = 125/212 (58%), Gaps = 5/212 (2%)
Frame = +2
Query: 23 AQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNA 202
A T M+T F++ D++ + RK+ +K KL + +K ANAL P NA
Sbjct: 406 AWTTIPMVTHFDKADVTAMEETRKR-FGARVEKEGGKLTMTHILMKVVANALRKFPKFNA 464
Query: 203 VIE--ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLT 376
++ ++IY+++V+I VAV TP GL+VPV+++ ++ L ++ LA +AR KL
Sbjct: 465 SLDLGAEQVIYKEFVNIGVAVDTPVGLLVPVVKDADRKGITELVLDLSELAGRARERKLK 524
Query: 377 IEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGM-HGIFERPI--ALNGQVVIRPMMY 547
+EM G TFTISN G G TPI+N P+ AILG+ G FE P+ G+ R M+
Sbjct: 525 PDEMQGATFTISNLGGIGGNAFTPIVNSPEVAILGVSRGGFE-PVWNKEKGEFEPRNMLP 583
Query: 548 IALTYDHRLIDGREAVLFLRKIKEGVEDPATI 643
++LTYDHRLIDG +A FLR I E +EDP I
Sbjct: 584 LSLTYDHRLIDGADAARFLRYICESLEDPFLI 615
>UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=41;
Streptococcus|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex -
Streptococcus pyogenes serotype M28
Length = 469
Score = 140 bits (338), Expect = 4e-32
Identities = 79/210 (37%), Positives = 119/210 (56%), Gaps = 9/210 (4%)
Frame = +2
Query: 32 TNAMLT----TFN-EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM--DQP 190
TN+ LT T N +IDM+ ++A RKK +D K +K+ A LM +
Sbjct: 255 TNSYLTAPTFTLNYDIDMTEMIALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHE 314
Query: 191 VVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKART 364
+NA + + N+I +V++ +AV GL+VPVI M+ +D L + +KA+T
Sbjct: 315 YMNASLINDANDIELHRFVNLGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQT 374
Query: 365 GKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMM 544
GKL EM G TF+I+N G+FG+ PIIN P SAILG+ P ++G++V RP+M
Sbjct: 375 GKLKAAEMSGSTFSITNLGMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIM 434
Query: 545 YIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+ LT DHRL+DG F+ +K+ +E+P
Sbjct: 435 AMCLTIDHRLVDGMNGAKFMVDLKKLMENP 464
>UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Halobacteriaceae|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex - Haloarcula
marismortui (Halobacterium marismortui)
Length = 545
Score = 139 bits (337), Expect = 6e-32
Identities = 75/202 (37%), Positives = 118/202 (58%), Gaps = 2/202 (0%)
Frame = +2
Query: 47 TTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI--EENE 220
T +++ +S ++ R++ L ++ + L VK A AL PV+N + E E
Sbjct: 343 THHDQVVVSGLVEARER-LAPLAEERDVTLTYTPFVVKCVAAALDKHPVLNTALDTENEE 401
Query: 221 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 400
I+YRD +I VA AT GLVVPV+ +V ++ + L +AR + EM GGT
Sbjct: 402 IVYRDAHNIGVAAATDHGLVVPVVNDVDGKGLVELAGEVNDLVGRARERDIERSEMQGGT 461
Query: 401 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 580
FT++N GV G +PIIN P++AILG+ + ERP+A +G+VV +P + ++L DHR+ID
Sbjct: 462 FTVTNFGVIGGEYASPIINVPETAILGIGALKERPVAEDGEVVAKPTLPLSLAIDHRVID 521
Query: 581 GREAVLFLRKIKEGVEDPATIV 646
G +A F+ +KE + DP ++
Sbjct: 522 GADAARFVNTLKEYLSDPTRLL 543
>UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Bdellovibrio bacteriovorus|Rep: Pyruvate dehydrogenase
E2 - Bdellovibrio bacteriovorus
Length = 543
Score = 138 bits (335), Expect = 1e-31
Identities = 77/220 (35%), Positives = 122/220 (55%), Gaps = 2/220 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ ++ +++ T +E + ++A R+ L +K+ K+ + +KA +
Sbjct: 324 IAENMQRSKHVIPHFTIMDEAKVDAMVALRES-LKEHAEKNGTKITYLPIIMKALIATIR 382
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P+ NA I++ EI+Y+ Y ++ A TP GLVVPVI+N + +I I L+++
Sbjct: 383 EFPMFNASIDDAAGEIVYKKYFNLGFAADTPNGLVVPVIKNADQKSILEISKEILDLSKR 442
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR GKL +EM G T T++N G G TP+IN P+ AILGM+ I E+ + NGQV
Sbjct: 443 ARDGKLKPDEMKGATITVTNIGSIGGTYATPVINHPEVAILGMYKIDEKVVLKNGQVSAI 502
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
+M +T DHRLIDG A FL +E+P ++ L
Sbjct: 503 KVMNYTMTADHRLIDGAVAARFLAAFIGRIENPGKLLVEL 542
>UniRef50_A6TMP1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Alkaliphilus
metalliredigens QYMF|Rep: Catalytic domain of components
of various dehydrogenase complexes - Alkaliphilus
metalliredigens QYMF
Length = 438
Score = 138 bits (335), Expect = 1e-31
Identities = 73/212 (34%), Positives = 129/212 (60%), Gaps = 2/212 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I +R+ ++ T +E+D++ ++A+R++ + F ++ IK+ + +KA AL
Sbjct: 220 IGKRMTESFYTAPHALCIDEVDVTDLVAYREEMKNHFVEEKEIKITYLPFMIKAVMLALK 279
Query: 182 DQPVVNAVI-EENE-IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
D P NA + EEN+ +I + Y +I +AV TP+GL VPVI++V + L++
Sbjct: 280 DYPRFNAQLDEENQMLILKKYYNIGIAVDTPEGLTVPVIKDVDQKGLMSLMEESVRLSQS 339
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
A+ L + ++ G TFTI+N G G G PIIN P+ AI+G+ I ++P+ ++ +VVIR
Sbjct: 340 AKDKSLKLNQLKGSTFTITNLGSLGVKSGMPIINYPEVAIIGIGQIEQKPVVVDNEVVIR 399
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
MM ++L++DHR++DG + FL + K+ ++D
Sbjct: 400 WMMPLSLSFDHRVLDGGDVGRFLNQFKKYIKD 431
>UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC -
Clostridium kluyveri DSM 555
Length = 444
Score = 138 bits (335), Expect = 1e-31
Identities = 76/215 (35%), Positives = 123/215 (57%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I+ R+ ++ + +T ID+S + + DTF KL +K + AL
Sbjct: 235 ISARMSESVKISPTVTYNINIDISELKRLKNNLKDTF------KLTYTDFLIKIVSAALK 288
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P+VN I + I +DYV++ VAVA +GL+VPV+++ I + +KA+
Sbjct: 289 QFPLVNCSISGGKFILKDYVNMGVAVALDEGLIVPVVKDTDIKGLKQIAEEFKEIVKKAK 348
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
+ L+ ++M GGTFTI+N G+ G +PIIN P+ AILG++ I + P+ ++V++P+
Sbjct: 349 SNSLSPDDMTGGTFTITNLGMLGIDSFSPIINQPEVAILGVNTIVDTPVVEGEKIVVKPL 408
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M ++LT DHR IDG A FL+KIKE +E P ++
Sbjct: 409 MKLSLTADHRAIDGAYAAKFLQKIKEYIEKPELLL 443
>UniRef50_P09062 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=27; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas putida
Length = 423
Score = 138 bits (334), Expect = 1e-31
Identities = 76/216 (35%), Positives = 132/216 (61%), Gaps = 2/216 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQR++DA+ A + EID++ + A R++ L++ KL L+ V+A AL
Sbjct: 206 IAQRMQDAKRRVAHFSYVEEIDVTALEALRQQ-LNSKHGDSRGKLTLLPFLVRALVVALR 264
Query: 182 DQPVVNAVIE-ENEIIYRD-YVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
D P +NA + E +II R V + +A GL+VPV+R+ + + I+ LA
Sbjct: 265 DFPQINATYDDEAQIITRHGAVHVGIATQGDNGLMVPVLRHAEAGSLWANAGEISRLANA 324
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR K + EE+ G T T+++ G G ++ TP++N P+ AI+G++ + ERP+ ++GQ+V+R
Sbjct: 325 ARNNKASREELSGSTITLTSLGALGGIVSTPVVNTPEVAIVGVNRMVERPVVIDGQIVVR 384
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATI 643
MM ++ ++DHR++DG +A LF++ ++ +E PA +
Sbjct: 385 KMMNLSSSFDHRVVDGMDAALFIQAVRGLLEQPACL 420
>UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3;
Cystobacterineae|Rep: Lipoamide acyltransferase -
Myxococcus xanthus
Length = 416
Score = 137 bits (332), Expect = 2e-31
Identities = 79/214 (36%), Positives = 121/214 (56%), Gaps = 3/214 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK-HLDTFTKKHSIKLGLMSPFVKAAANAL 178
IA+++ ++ T E+D + ++A R + + +IKL + +KA AL
Sbjct: 195 IAEKMVRSKFTAPHFAFVEEVDATELVALRARLNAQLAAAGENIKLNYLPFIIKATVAAL 254
Query: 179 MDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAE 352
P +NA +E E++ R +I +A ATP GL V V+++ +T A++ A L
Sbjct: 255 KKFPHLNANFDEASQELVVRGEFNIGMAAATPDGLTVAVVKSADRLTLAELARETARLGA 314
Query: 353 KARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVI 532
AR KL +EE+ GGTFTIS+ G G L TPIIN P+ ILG+H + +RP + QVV+
Sbjct: 315 AARDRKLKMEELTGGTFTISSLGQSGGLFATPIINHPEVGILGVHRLKKRPAVVGDQVVV 374
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
R MM ++L+ DHR+IDG A F +I + +E P
Sbjct: 375 RDMMNLSLSCDHRVIDGSVAADFTYEIIKYLEKP 408
>UniRef50_Q1AZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 396
Score = 137 bits (332), Expect = 2e-31
Identities = 64/192 (33%), Positives = 118/192 (61%)
Frame = +2
Query: 59 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY 238
++D S ++ R++ + H + L ++A A A ++P+ N+ + + EI+ +
Sbjct: 201 QLDASALVGRRRELAGQIKRSHGVDLSYTDLLLEAVAGAAGEEPLANSSLVDGEILLYED 260
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
V++SVAVAT GL+VPV+R Q + ++ + + E+AR+G+L+ E+ GGT T+SN
Sbjct: 261 VNVSVAVATGSGLLVPVVRWAQALELGELAARLREVLERARSGRLSAEDTAGGTITLSNL 320
Query: 419 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 598
G++G GTP++ PQ+A++ I ERP A++G+V +RP + +++ +DHR++DG A
Sbjct: 321 GMYGIEGGTPLVTHPQAAVVFAGAIVERPWAVSGRVEVRPTLTLSVGFDHRILDGVAAAR 380
Query: 599 FLRKIKEGVEDP 634
F ++ +E P
Sbjct: 381 FTTALRRRLESP 392
>UniRef50_Q97Y19 Cluster: Dihydrolipoamide S-acetyltransferase,
carboxy-end; n=2; cellular organisms|Rep:
Dihydrolipoamide S-acetyltransferase, carboxy-end -
Sulfolobus solfataricus
Length = 177
Score = 137 bits (332), Expect = 2e-31
Identities = 71/168 (42%), Positives = 104/168 (61%)
Frame = +2
Query: 128 IKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQN 307
+K+ VK A L D P +NA +E ++I + V+I +AVA +GL+VPVIRN
Sbjct: 1 MKITYTDILVKVVAKLLRDHPYLNATLEGDQIKIIEEVNIGIAVALDQGLIVPVIRNADT 60
Query: 308 MTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMH 487
+I LA+KAR KL +E+ GGTFTISN G++ TPIINPPQ+AILG+
Sbjct: 61 KPITEIAKESHELADKARENKLNPDEVSGGTFTISNLGMYDIDSFTPIINPPQTAILGVG 120
Query: 488 GIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
I P+ + + I +M+++LT+DHR++DG A FL+++ E +ED
Sbjct: 121 RIRRAPVVVGDNISIGYIMWLSLTFDHRVMDGHTAAKFLKELTEILED 168
>UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacteria
(class)|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 487
Score = 136 bits (329), Expect = 5e-31
Identities = 75/219 (34%), Positives = 124/219 (56%), Gaps = 7/219 (3%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+R+ ++ +A LTT E D++ I R + F + IKL + F A AL
Sbjct: 262 VARRMVESLQISAQLTTVVEADVTRIARLRDRAKSGFQAREGIKLSFLPFFALATCAALR 321
Query: 182 DQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P +N+ I E + Y ++ +AV + +GLVVPVI N ++ + I LA +
Sbjct: 322 EFPQLNSSIDVEAGTVTYHGEENLGIAVDSERGLVVPVIHNAGDLNLIGLARKIDDLASR 381
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN----GQ 523
R +++ +E+ GGTFT++N G G+L TPIIN PQ ILG + ++P ++ G+
Sbjct: 382 TRANRISPDELGGGTFTLTNTGSRGALFDTPIINQPQVGILGTGIVTKKPAVVDDPELGE 441
Query: 524 VV-IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPA 637
++ +R +Y++LTYDHR++DG +A FL K +E+ A
Sbjct: 442 IIAVRSTVYLSLTYDHRIVDGADAARFLAFTKHRLENGA 480
>UniRef50_Q1AT73 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 441
Score = 136 bits (329), Expect = 5e-31
Identities = 68/211 (32%), Positives = 124/211 (58%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+R+ ++ T E D+S ++ R+ + F ++ + L + V+A +L
Sbjct: 222 IAERMSRSKREAPHAWTLVEADVSGLVGLREARKEEFRRREGVNLTYLPFVVRAVVESLK 281
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKA 358
+ PV+N+V + + I+ R ++I +AV +G L+VPVI++ + + I + +A
Sbjct: 282 EHPVLNSVWDGDRIVLRKRINIGIAVDLEEGALIVPVIKDADDYGIVGLARRIDEVVRRA 341
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIR 535
R +L+ +++ GGTFT++N G GS++ TPIIN PQ+AIL I +RP+ L + + +R
Sbjct: 342 RQRRLSPDDVSGGTFTVNNPGALGSVVSTPIINHPQAAILSAEAIVKRPVVLEDDAIAVR 401
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
MM + +++DHR++DG A+ FL +K +E
Sbjct: 402 SMMNLEVSFDHRILDGGAALRFLNAVKRRLE 432
>UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=5;
Legionellales|Rep: Pyruvate dehydrogenase E2 component -
Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 550
Score = 136 bits (328), Expect = 7e-31
Identities = 78/190 (41%), Positives = 111/190 (58%), Gaps = 2/190 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 217
+T F+E D++ + AFRK ++ K KL L++ AL P NA ++ +
Sbjct: 348 VTQFDEADITDLEAFRKSESES-AKNQDYKLTLLAFVCSVVCKALHAYPQFNASLDTSGE 406
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
+IY+ Y +I +AV TP GLVVPVI+NV ++ DI ++ L+ KAR LT +M GG
Sbjct: 407 NLIYKKYYNIGIAVDTPNGLVVPVIKNVDKLSVIDIAKEMSRLSTKAREKGLTPIDMSGG 466
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
FTIS+ G G TPI+N P+ AILG+ +PI N + R M+ I+L+YDHR+I
Sbjct: 467 CFTISSLGGIGGTAFTPIVNSPEVAILGLSRSIIKPIYDNKEFKPRLMLPISLSYDHRVI 526
Query: 578 DGREAVLFLR 607
DG EA F R
Sbjct: 527 DGAEAARFTR 536
>UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Acidobacteria bacterium Ellin345|Rep: Dihydrolipoamide
acetyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 615
Score = 136 bits (328), Expect = 7e-31
Identities = 81/216 (37%), Positives = 120/216 (55%), Gaps = 2/216 (0%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A+RL A T +T + D++ + R+K + KL + + +K A A+
Sbjct: 398 AERLTQAWTTIPHVTQHDRADITELEKLREKFAKQ-AEAAGGKLTVTAIALKVIAAAMKK 456
Query: 185 QPVVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P NA I+ EIIY+ YV I VAV T GL+VPV+RNV I + L+++A
Sbjct: 457 FPKFNASIDIDREEIIYKKYVHIGVAVDTEAGLLVPVLRNVDQKNVYQIAAEMNELSKRA 516
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRP 538
R KL EEM+GGTFTI+N G G TPI+N P+ AILG+ P+ +N R
Sbjct: 517 RERKLKPEEMEGGTFTITNLGGIGGTSFTPIVNLPEVAILGLSRGRTEPVWVNDHFEPRT 576
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M+ ++L+YDHR+IDG +A +LR + + +E P ++
Sbjct: 577 MLPLSLSYDHRIIDGADAARYLRWVADALEQPVLLL 612
>UniRef50_Q088Y7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Shewanella frigidimarina NCIMB
400|Rep: Dihydrolipoyllysine-residue succinyltransferase
- Shewanella frigidimarina (strain NCIMB 400)
Length = 252
Score = 136 bits (328), Expect = 7e-31
Identities = 76/208 (36%), Positives = 121/208 (58%), Gaps = 9/208 (4%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKK-----HLDTF--TKKHSIKLGLMSPFVKAAANALMDQPVVNA 202
+T +E+D+ I A R K D T++ I L+ +KA AL P NA
Sbjct: 43 VTHHDEVDIGAIEALRHKLNIEHSADVLGVTEEAQIHFTLLPFILKATIEALKLFPAFNA 102
Query: 203 VIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLT 376
+ ++ ++ + Y ++ +AV T GL+VPVI+NV +T ++ + LAE+ R GKLT
Sbjct: 103 SLSDDGETLMLKHYYNLGIAVDTSNGLLVPVIKNVDALTLEELAIASQQLAERTRAGKLT 162
Query: 377 IEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIAL 556
+ +GG+FT+++ G G TPIIN P+ AILG+ + +A NGQ+VIRPM+ ++L
Sbjct: 163 FADTEGGSFTVTSLGPMGGTSFTPIINMPEVAILGVSREITKVVAQNGQIVIRPMLPLSL 222
Query: 557 TYDHRLIDGREAVLFLRKIKEGVEDPAT 640
+YDHR+IDG A F+ ++K+ + T
Sbjct: 223 SYDHRVIDGAMATRFMVQLKQNLSQAET 250
>UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Halobacterium salinarum|Rep: Dihydrolipoamide
S-acetyltransferase - Halobacterium salinarium
(Halobacterium halobium)
Length = 478
Score = 135 bits (326), Expect = 1e-30
Identities = 77/217 (35%), Positives = 123/217 (56%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I +++ +++ T +T + + ++ R K L + +KL M +KA AL
Sbjct: 261 IGEQMAESKYTAPHVTHHDTAVIDSLVETRSK-LKARAEAEDVKLTYMPFVMKAVVAALK 319
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ PV+N+ + E+ EI + +I VAVAT GL+VPV+ +V + +I + L E+
Sbjct: 320 EFPVLNSELREDDEEIALKQDYNIGVAVATDAGLMVPVVEHVDQKSMLEISTEMNDLVEQ 379
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR + +MDGGTFTI+N G G TPIIN P++AILG+ I ERP+A +G V
Sbjct: 380 ARERSIAPADMDGGTFTITNFGAIGGEYATPIINYPETAILGLGAIDERPVAEDGDVRAA 439
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ ++L+ DHR+IDG EA F ++ E + DP ++
Sbjct: 440 QTLPLSLSIDHRVIDGAEAAQFTNRVMEYLTDPELLL 476
>UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransferase
component; n=1; marine actinobacterium PHSC20C1|Rep:
Putative dihydrolipoamide acyltransferase component -
marine actinobacterium PHSC20C1
Length = 480
Score = 134 bits (325), Expect = 2e-30
Identities = 74/203 (36%), Positives = 115/203 (56%), Gaps = 2/203 (0%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAV--IEEN 217
+T F ID++ M K K +++ KA + P VN+ E N
Sbjct: 280 VTEFLTIDVTRTMELVAK-----LKAGGTAASVLAVLAKALCIGVARNPSVNSRWDAEAN 334
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
EI+ YV++ +AVATP+GL+VP +++ MT A++ I LA AR K T ++GG
Sbjct: 335 EIVEFGYVNLGIAVATPRGLMVPNLKDADMMTLAELTEAIGTLARNARASKATPASLNGG 394
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
T +I+N GVFG GTPI+NP ++AIL M + + P NG+V +R +M ++L++DHRL+
Sbjct: 395 TISITNVGVFGIDAGTPILNPGEAAILAMGAVRKMPWEHNGEVALRDVMTLSLSFDHRLV 454
Query: 578 DGREAVLFLRKIKEGVEDPATIV 646
DG + FL + + DP T++
Sbjct: 455 DGEQGARFLTDVGAILNDPGTVL 477
>UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Thermobifida fusca YX|Rep: Pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase - Thermobifida fusca (strain YX)
Length = 431
Score = 134 bits (324), Expect = 2e-30
Identities = 70/215 (32%), Positives = 119/215 (55%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL A+ ID + FR + ++ +K+ + VKA A L
Sbjct: 217 IARRLTQAKQEIPHFYLRRRIDAEALREFRAQ-INEQLAPTGVKVSVNDLIVKAVATVLR 275
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
D P VN+ +++++ +++ +AVA GLVVPV+ + + +++ L EKAR
Sbjct: 276 DHPEVNSSWVDDKLLRHKRINVGIAVAVDTGLVVPVLHDADTLALSEVARRSRALVEKAR 335
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKL+ ++M GGTF++SN G+FG + +INPP++AIL + + + P+ +G++V R
Sbjct: 336 DGKLSPQDMSGGTFSVSNLGMFGVESFSAVINPPEAAILAVGAMQQEPVVRDGEIVARHT 395
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ + L+ DHR +DG FL+ + E +E P IV
Sbjct: 396 IALELSVDHRAVDGAVGAAFLKDLAEVLESPMRIV 430
>UniRef50_A0LLM2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Catalytic domain of components of
various dehydrogenase complexes - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 443
Score = 134 bits (323), Expect = 3e-30
Identities = 77/200 (38%), Positives = 117/200 (58%), Gaps = 6/200 (3%)
Frame = +2
Query: 65 DMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI--EENEIIYRDY 238
D++ + AFR+KH + L ++ +KAA AL P NA I E EI+++ Y
Sbjct: 242 DITELDAFRRKHKAEIREAGGA-LNMIVFVLKAAVAALKAFPGFNASIDPEREEIVFKRY 300
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
+I VAV T +GL+VPVIR+V + ++ + + +AE+ R GK EEM GGTFT++N
Sbjct: 301 YNIGVAVDTDRGLIVPVIRDVDRKSVRELAVELLDVAERTRRGKAEREEMTGGTFTLTNI 360
Query: 419 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNG----QVVIRPMMYIALTYDHRLIDGR 586
G G TPIIN PQSAILGM +P+ ++V R ++ + + +DHR++DG
Sbjct: 361 GALGGTAFTPIINHPQSAILGMGQARLQPVVRGDLERHEIVPRLLLPLIVAFDHRIVDGA 420
Query: 587 EAVLFLRKIKEGVEDPATIV 646
+A FL I E +E+P ++
Sbjct: 421 DAARFLGMIIEALENPEELL 440
>UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=3; Mollicutes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
capricolum subsp. capricolum (strain California kid /
ATCC27343 / NCTC 10154)
Length = 438
Score = 134 bits (323), Expect = 3e-30
Identities = 75/204 (36%), Positives = 117/204 (57%), Gaps = 2/204 (0%)
Frame = +2
Query: 38 AMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAV--IE 211
A T D++ R + L IKL ++ +KA A +L D P +N
Sbjct: 234 AAFTGMKNTDITETHKMRTE-LKDHAAASGIKLTYLAFIIKAVAKSLRDMPNINVRGDFA 292
Query: 212 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 391
N+I + ++I +AV TP GL+VPVI+ +++ +I + I+ LA KA+ GKLT EM
Sbjct: 293 NNKIQFMHNINIGIAVDTPNGLMVPVIKGADHLSVFEIAIKISELANKAKDGKLTRAEMT 352
Query: 392 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 571
TFT+SN G G TPIIN P+SAILG+ + + P+ +NG++ R +M +++T DHR
Sbjct: 353 EATFTVSNFGSVGLDYATPIINSPESAILGVGTMSQTPLYINGELQKRFIMPLSMTCDHR 412
Query: 572 LIDGREAVLFLRKIKEGVEDPATI 643
+IDG +A FL K+++ + P +
Sbjct: 413 IIDGADAGRFLIKVQDYLSKPVLL 436
>UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3;
Gammaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Acinetobacter sp. (strain ADP1)
Length = 513
Score = 133 bits (322), Expect = 4e-30
Identities = 81/217 (37%), Positives = 120/217 (55%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RL+ A+ E+++ + A R++ DT + +KL + +KAAA AL+
Sbjct: 299 IASRLQLAKRNAPHFRLSIEVNVEALQALRQQINDTVPQ---LKLSINDMLIKAAAAALI 355
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P VN +E +I+ DISVAVA GL+ P+++ + A I T+ LA +
Sbjct: 356 KVPEVNVQYDEQKQQILQFKDADISVAVAIENGLITPIVKAANQKSLATISSTMRDLATR 415
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
A+TGKL +E GG+F+ISN G+ G IINPPQ AI+ + R + + +VIR
Sbjct: 416 AKTGKLQPDEFQGGSFSISNLGMLGIKNFDAIINPPQGAIMALGRSEARAVVEHDLIVIR 475
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MM + L+ DHR+IDG FL K+ VE+PA I+
Sbjct: 476 QMMTVTLSCDHRVIDGALGAKFLASFKQFVENPALIL 512
>UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzymes; n=1; Nitrosococcus oceani ATCC
19707|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzymes - Nitrosococcus oceani (strain ATCC
19707 / NCIMB 11848)
Length = 447
Score = 133 bits (322), Expect = 4e-30
Identities = 79/199 (39%), Positives = 115/199 (57%), Gaps = 2/199 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 217
+T ++ D++ + RK+ + KL L + +K AA AL P N I+ +
Sbjct: 243 VTQHDQADITRLEQARKRFAKRVEQAGG-KLTLTAIALKVAAAALQAFPRFNTSIDVDAK 301
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
E++Y+ Y I VAV GL+VPVIR A + + + LAEKAR+ K+ EEM GG
Sbjct: 302 ELVYKQYCHIGVAVDAEHGLLVPVIREADQKNIAQLAVELTELAEKARSRKIGPEEMAGG 361
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
+FTI+N G G TPIIN P+ AILG+ P+ + G+ R ++ ++L+YDHR+I
Sbjct: 362 SFTITNLGGLGGSYFTPIINWPEVAILGLSRAKMAPLYIEGEFQPRLLLPLSLSYDHRVI 421
Query: 578 DGREAVLFLRKIKEGVEDP 634
DG +AV FLR I E +EDP
Sbjct: 422 DGADAVRFLRWIVEALEDP 440
>UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha keto acid
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Plesiocystis pacifica SIR-1
Length = 435
Score = 133 bits (322), Expect = 4e-30
Identities = 72/222 (32%), Positives = 130/222 (58%), Gaps = 4/222 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + + T +ID++ ++ RK+ ++ + L + +KA +AL
Sbjct: 215 IAEGMVKSYTEAVHYTYVEQIDVTKLVTLRKQAKKAAAEQ-GVSLSYLPFIIKAVCHALK 273
Query: 182 DQPVVNAVIEENE--IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P+VNA ++E + I+ + I VA AT +GL+VPVI + ++ D+ + L E
Sbjct: 274 RFPIVNAELDEAQKRIVLKKRYSIGVAAATDQGLMVPVIHDADMLSLLDLAREVKRLGEG 333
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVI 532
A+TG+L +E+ G TFTI++ G G ++ TPI+N P+ ILG+H I + P+ N ++VI
Sbjct: 334 AKTGRLARDELTGSTFTITSLGTIGGVLATPILNYPEVGILGVHAIRKVPVVNDNDEIVI 393
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPA-TIVAGL 655
+M ++++ DHR++DG E FL++++ +EDP ++AG+
Sbjct: 394 GHIMNLSVSLDHRVVDGFEGASFLQEVRRYLEDPTLLLLAGI 435
>UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=10; Rickettsia|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rickettsia conorii
Length = 412
Score = 133 bits (322), Expect = 4e-30
Identities = 75/215 (34%), Positives = 116/215 (53%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++ T E ++ ++ R+ F++ S ++ + + A A AL
Sbjct: 197 IAKRLLESKQTVPHFYLSIECNVDKLLDIREDINKFFSEDKSTRISVNDFIILAVAKALQ 256
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P NA E+ I Y + VDISVAVA GLV P+++N ++ + L +KA+
Sbjct: 257 EVPNANASWGEDAIRYYNNVDISVAVAIENGLVTPIVKNANQKNILELSREMKALIKKAK 316
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KLT EE GG FTISN G++G IINPPQS I+G+ +R I N Q+ I +
Sbjct: 317 DNKLTPEEFQGGGFTISNLGMYGIKNFNAIINPPQSCIMGVGASAKRAIVKNDQITIATI 376
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M + L+ DHR++DG FL K+ +E P ++
Sbjct: 377 MDVTLSADHRVVDGAVGAEFLVAFKKFIESPVLML 411
>UniRef50_Q14Q97 Cluster: Putative uncharacterized protein; n=1;
Spiroplasma citri|Rep: Putative uncharacterized protein -
Spiroplasma citri
Length = 992
Score = 133 bits (321), Expect = 5e-30
Identities = 76/203 (37%), Positives = 119/203 (58%), Gaps = 3/203 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEE--N 217
LT +EIDMS I+ ++K L H ++ MS VKA + L + P +N+ + N
Sbjct: 788 LTINSEIDMSSIIDQQRK-LKNANADHGVRFSTMSFLVKAVSLVLSEYPKLNSYYDSKTN 846
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
+I+ ++ I +A T +GLV+PVI+ + M+ I + I E+ R G+L E+ G
Sbjct: 847 QIVIKNSQHIGLATETSEGLVIPVIKFAERMSLKQIAINIQETIERLRQGELYDYELKGS 906
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNG-QVVIRPMMYIALTYDHRL 574
T TI+N G+ G++ TP I P SA++G+ I +PI + G ++VIR +M +ALT D R+
Sbjct: 907 TITIANYGMVGAVNATPTIFYPNSAVIGVGRIVRKPIVIKGDKLVIRSIMNLALTIDQRI 966
Query: 575 IDGREAVLFLRKIKEGVEDPATI 643
ID EA +FL ++KE +E P I
Sbjct: 967 IDAAEAGIFLTRVKEILESPELI 989
>UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=7; Bacteria|Rep:
Pyruvate dehydrogenase complex dihydrolipoamide
acetyltransferase - Microscilla marina ATCC 23134
Length = 547
Score = 132 bits (320), Expect = 6e-30
Identities = 75/212 (35%), Positives = 119/212 (56%), Gaps = 1/212 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL ++ T EI M IM RK+ +K+ +KA+A A+
Sbjct: 335 IAKRLASSKFTAPHFYVTMEIRMDAIMKARKQ----INAVSPVKVSFNDIIIKASALAIR 390
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +NA E++I Y +++ + +AVA GL VPV+R N+T++ + T L KA+
Sbjct: 391 KHPKINAYWLEDKIRYNNHIHVGMAVAVKDGLFVPVVRFADNLTFSQVATTTKDLVSKAK 450
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN-GQVVIRP 538
KL + +G TF++SN G+FG T IINPP S IL + GI + P+ + GQ+ +
Sbjct: 451 DKKLQPADWEGSTFSVSNLGMFGVEDFTAIINPPDSCILAVGGIKQTPVVNDEGQIEVGN 510
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+M + L+ DHR++DG A FL+ +K+ +E+P
Sbjct: 511 IMKVTLSSDHRVVDGALAASFLKTLKQMIENP 542
>UniRef50_A0JUQ7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=9; Actinobacteria
(class)|Rep: Catalytic domain of components of various
dehydrogenase complexes - Arthrobacter sp. (strain FB24)
Length = 462
Score = 132 bits (320), Expect = 6e-30
Identities = 73/203 (35%), Positives = 115/203 (56%), Gaps = 2/203 (0%)
Frame = +2
Query: 47 TTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEE--NE 220
T F ID++ M + L KL ++ KA AL QP +N+ +E E
Sbjct: 259 TEFLTIDVTPTMELLSR-LKASRTFEGFKLTPLTLVAKALLIALRRQPSLNSRWDEANQE 317
Query: 221 IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 400
I+ +YV++ +A ATP+GL VP I++ +M+ ++ + L E AR GK + E+ GGT
Sbjct: 318 IVQYNYVNLGIAAATPRGLTVPNIKDAHSMSLTELSTALTALTETARAGKTSPAELTGGT 377
Query: 401 FTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLID 580
+I+N GVFG GTPI+NP ++AIL M + + P +V +R +M ++L++DHRL+D
Sbjct: 378 ISITNIGVFGIDAGTPILNPGEAAILAMGAVRKMPWEYRDEVALRQVMTLSLSFDHRLVD 437
Query: 581 GREAVLFLRKIKEGVEDPATIVA 649
G + FL I + DP ++A
Sbjct: 438 GEQGSRFLADIGAVLADPGMVLA 460
>UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=11; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Psychroflexus torquis
ATCC 700755
Length = 572
Score = 132 bits (319), Expect = 8e-30
Identities = 76/216 (35%), Positives = 118/216 (54%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++N+ E+DM + MA R H++ +K+ +KA+A AL
Sbjct: 361 IAKRLLESKNSAPHYYLNIEVDMENAMASRS-HINEMP---DVKVSFNDLVIKASAMALR 416
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN+ + +++ + VAVA +GL+VPV+ + I + LA KA+
Sbjct: 417 KHPQVNSSWDGEVTKIANHIHVGVAVAVDEGLLVPVLEFADQQSLTQIGSNVKNLAGKAK 476
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KL EM+G TFT+SN G+FG T IIN P SAIL + I E+P+ G++V+
Sbjct: 477 NKKLQPNEMEGSTFTVSNLGMFGITEFTSIINQPNSAILSVGTIVEKPVVKKGEIVVGHT 536
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVA 649
M + L DHR +DG FL+ +K +E+P T++A
Sbjct: 537 MILTLACDHRTVDGATGAKFLQTLKIYLENPVTMLA 572
>UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 436
Score = 131 bits (317), Expect = 1e-29
Identities = 74/213 (34%), Positives = 119/213 (55%), Gaps = 2/213 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQ + + T +T F E D + ++ R++ + ++ +KL ++ VKA A L
Sbjct: 219 IAQAMVRSTRTIPQVTHFGEADATRLVQHRRR-IQPLAEQQGVKLTYLAYVVKALAAVLK 277
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P++NA ++E EI+ +++ I AV T +GL+VPVIR+ + I I L K
Sbjct: 278 KYPMLNASLDEEREEIVIHEFIHIGFAVDTDRGLLVPVIRDADQKSLFQIAKEIEELTAK 337
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR G + EM GGT T+SN G TPII+ PQS +LG+ + ++P+ ++ + I
Sbjct: 338 ARAGTIQAVEMSGGTCTVSNIGSANGSWFTPIIHYPQSCLLGIGKVEKKPVVVDDSIEIA 397
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+M ++LTYDHRLIDG A L + + + +P
Sbjct: 398 SVMPLSLTYDHRLIDGMMAQHALNECQTYLSEP 430
>UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=13; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Robiginitalea biformata HTCC2501
Length = 476
Score = 131 bits (317), Expect = 1e-29
Identities = 70/214 (32%), Positives = 126/214 (58%), Gaps = 5/214 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + ++ +T+A + +F E+D++ I+ +R + F K+ KL F++A A AL
Sbjct: 255 IAKHMAESVSTSAHVQSFVEVDVTRIVEWRDRVKADFEKREGEKLTFTPIFMEAVAKALK 314
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKG-LVVPVIRNVQNMTYADIELTIAGLAEKA 358
P++N ++ + +I + +++ +A A P G L+VPVIRN + + + LA +A
Sbjct: 315 KFPMMNISVDGDRVIKKKQINLGMAAALPDGNLIVPVIRNADQLNLVGMARAVNDLATRA 374
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL---NGQVV 529
R L +E+ GT+T++N G FGS+ GTPIIN PQ IL + I + P + +G +
Sbjct: 375 RNNALKPDEVRDGTYTVTNVGSFGSVFGTPIINQPQVGILALGAIRKVPAVIETPSGDFI 434
Query: 530 -IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
IR M+++ +YDHR+++G LF++ + + +E
Sbjct: 435 GIRSKMFLSHSYDHRVVNGALGGLFVKAVADYLE 468
>UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3;
Lactobacillales|Rep: Dihydrolipoamide acyltransferase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 432
Score = 131 bits (316), Expect = 2e-29
Identities = 71/209 (33%), Positives = 115/209 (55%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+++ + N E D+++++ R D F ++ + L F KA AL
Sbjct: 214 IAKKMVQSVNEIPHAWLMVEADVTNLVQLRNSLKDEFKQQEGLSLSFFPFFAKAVIQALK 273
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +N ++ IIY V++S+AV T + L VPVI+ N + A + I LA++ R
Sbjct: 274 KNPKINTSWDDGSIIYHKDVNLSIAVTTDEHLYVPVIQQADNYSIAGLAKEINRLAQEVR 333
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPI-ALNGQVVIRP 538
G L +EM GGTFT++N G GS+ IIN PQ+AIL + I +R + +G +
Sbjct: 334 QGTLASKEMQGGTFTLNNTGTLGSVQSMGIINHPQAAILQVESINKRLVPTADGGFKVAD 393
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGV 625
M+ + L+ DHR++DG++A FLR +K+ +
Sbjct: 394 MVNLCLSIDHRILDGQQAGKFLRDVKDNL 422
>UniRef50_A4WK39 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Pyrobaculum|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 408
Score = 131 bits (316), Expect = 2e-29
Identities = 72/213 (33%), Positives = 128/213 (60%), Gaps = 3/213 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFV-KAAANAL 178
+A+++ + + F E+D++ +++ R++ L ++ +KL + PFV KA A AL
Sbjct: 190 VAEKMAKSASAIPHAYHFEEVDVTELVSLRER-LRQEAERLGVKLTYL-PFVAKAVAVAL 247
Query: 179 MDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAE 352
+ P++N+ +E EI+ + + + AV T +GL+V V+R+ + +I + LAE
Sbjct: 248 REFPMLNSSFDEERGEIVVKRRIHLGFAVDTEQGLMVVVVRDADKKSVLEIARELNALAE 307
Query: 353 KARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVI 532
+AR GK +++E+ G TFTI+N G G + G PIIN P++AI+ + I + P +NG VV
Sbjct: 308 RARAGKASVDEVRGSTFTITNIGAIGGVGGLPIINYPEAAIMALGKIRKIPRVVNGAVVP 367
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
R +M + + +DHR++DG F ++KE +ED
Sbjct: 368 RDVMNVVVGFDHRVVDGAYVARFTNRVKELLED 400
>UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4;
Bacillaceae|Rep: Pyruvate dehydrogenase E2 -
Oceanobacillus iheyensis
Length = 420
Score = 130 bits (315), Expect = 3e-29
Identities = 75/221 (33%), Positives = 123/221 (55%), Gaps = 3/221 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+++ + T + E+DM+ ++ FRK+ K + + + F+KA AL
Sbjct: 205 IAKKMTTSIYTIPHVHHMEEVDMTELLEFRKEI------KSDADISVAAFFIKALTIALK 258
Query: 182 DQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P+ NA + E+ EI + + +A T +GL+VPVI++ + I + L +K
Sbjct: 259 EYPIFNAKLHEEKEEIRLEKGIHMGIATDTEEGLIVPVIQSADIKSIRTIHREMKELMKK 318
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVI 532
A+ L+++EM G TFTISN G GS+ TPIIN P+ A++ H + P+ N ++VI
Sbjct: 319 AKENTLSLKEMTGSTFTISNVGPMGSIGATPIINYPEVALMAFHKTKKAPVVNDNDEIVI 378
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
R MM + LT+DHR+ DG A+ F K K +E+P ++ L
Sbjct: 379 RSMMNVTLTFDHRVTDGGNAIAFTNKFKALIENPRLLLIEL 419
>UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1;
gamma proteobacterium HTCC2207|Rep: Dihydrolipoamide
acetyltransferase - gamma proteobacterium HTCC2207
Length = 496
Score = 130 bits (315), Expect = 3e-29
Identities = 73/215 (33%), Positives = 119/215 (55%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RL+ ++ T + ++ ++A RK+ + T K+ + VKA A+AL+
Sbjct: 284 IAARLQASKQTAPHFRVHIDAEIDALLAVRKQINSSNT---DAKVSVNDFIVKACASALI 340
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +N + ++ Y DISVAVA GL+ P++ + + +I T LA +A+
Sbjct: 341 KVPALNVQFDGEQLSYFSNADISVAVAIDDGLITPIVSDANHKGLVEISNTTRDLATRAK 400
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G+L EE GG+F ISN G++G IINPPQ AIL + +RP+ +G++ + +
Sbjct: 401 LGRLKPEEFQGGSFCISNLGMYGIKQFDAIINPPQGAILAVGAGEQRPVVKDGELAVATV 460
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M + L+ DHR+IDG A F+ +K +E PAT++
Sbjct: 461 MSLTLSSDHRIIDGAVAAQFMSVLKGYLEQPATML 495
>UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2
component, dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Pyruvate
dehydrogenase complex , E2 component, dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 442
Score = 130 bits (315), Expect = 3e-29
Identities = 74/216 (34%), Positives = 119/216 (55%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA R+ A ++ +I+M +M R + +++ + VKA +L
Sbjct: 230 IANRMVQASAGVPVIYLTTKIEMDRLMDLRAQ----INSMEGVRISINDFIVKACGLSLA 285
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +N + ++I+ + VDISVAV+ P GL+ P++R+ + A I + L KAR
Sbjct: 286 KFPAMNGAFQGDKIVQFNDVDISVAVSIPDGLITPIVRSADSKGLASISKDVKSLVGKAR 345
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMG-TPIINPPQSAILGMHGIFERPIALNGQVVIRP 538
+ L+ EE GG+FTISN G+FG++ T I+NPPQSAIL + G E +NG+V
Sbjct: 346 SNSLSPEEYQGGSFTISNLGMFGAVDSFTAILNPPQSAILAVAGTQEELKLVNGEVKSAK 405
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ + +T DHR+IDG A F+ +K+ +E PA ++
Sbjct: 406 VCKMTITCDHRVIDGALAAEFMNALKDYLETPAKLI 441
>UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Novosphingobium aromaticivorans|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Sphingomonas aromaticivorans
Length = 406
Score = 130 bits (314), Expect = 3e-29
Identities = 77/216 (35%), Positives = 127/216 (58%), Gaps = 5/216 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQR+ +A LT E+D++ + A R+ + + LG+++ +AA AL+
Sbjct: 199 IAQRMVEAAAIPT-LTADMEVDLTALFARRR----SVEGNGASVLGMIA---EAAIAALL 250
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+NA E+ ++ V + +AV TP+GLVVPV+RN +++ + IA LA+KAR
Sbjct: 251 QHRRLNAHWREDAMVQFGAVHLGIAVDTPEGLVVPVVRNAESLNARGLTDAIAALADKAR 310
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLM-GTPIINPPQSAILGMHGIFERPIALNG----QV 526
G L ++M+GGTFTISN G G ++ ++NPPQ A+LG+ GI P+A+ +
Sbjct: 311 AGTLRPQDMEGGTFTISNPGSMGPVVRAEALLNPPQVALLGLPGIVRAPVAIKDGDAWAM 370
Query: 527 VIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+RP++ ++L++DHR +DG + FL +K +E P
Sbjct: 371 AVRPLLRLSLSFDHRALDGGPVIAFLNTLKATLERP 406
>UniRef50_A5IXN4 Cluster: Dihydrolipoamide acetyltransferase
component ofpyruvate deshydrogenase complex; n=1;
Mycoplasma agalactiae|Rep: Dihydrolipoamide
acetyltransferase component ofpyruvate deshydrogenase
complex - Mycoplasma agalactiae
Length = 244
Score = 130 bits (314), Expect = 3e-29
Identities = 77/214 (35%), Positives = 121/214 (56%), Gaps = 3/214 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ LK+ ++A + + D++++ R K D +H++KL +S VKA+A AL
Sbjct: 25 IAKNLKEVLESSAYCSLVLKADVTNLWNLRAKVKDKVFAEHNVKLTFLSWIVKASAIALS 84
Query: 182 DQPVVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P A + E ++ Y ++I +AV TP GL VPVIR V+N++ DI+ I L+
Sbjct: 85 EYPSFAARWDGVEGKVYYPGTLNIGIAVDTPFGLFVPVIRGVENLSIIDIQKEIVRLSTL 144
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIF-ERPIALNGQVVI 532
AR KL + +M GG F I+N G G L G+PI+N +AI I E + G V
Sbjct: 145 ARDKKLKMSDMSGGCFAITNVGSAGVLFGSPIMNKGNTAISATGAIIDELKLNKEGAVEN 204
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
R +MY+++ DH+ +DG + F +IKE +E+P
Sbjct: 205 RKVMYLSIAADHQWVDGADMARFQGRIKELIENP 238
>UniRef50_A1SQB9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 474
Score = 130 bits (314), Expect = 3e-29
Identities = 75/219 (34%), Positives = 126/219 (57%), Gaps = 6/219 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+ Q + + T +T + +D++ M ++ L T + +++ + +A A+
Sbjct: 253 MGQAMVQSAFTLPHVTEWVTVDVTATMELVER-LKTRREFREVRVSPLLVLARAVMLAMR 311
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P +N+ ++ +E++Y+ YV++ +A ATP+GLVVP +++ ++MT ++ I +
Sbjct: 312 RTPEINSWWDDAAHEVVYKRYVNLGIAAATPRGLVVPNVKDAESMTLLELAQAINAVTAT 371
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP--IALNGQ-- 523
AR GK EM GGTFTI+N GVFG GTPIINP +SAIL + ++P + +GQ
Sbjct: 372 AREGKTQPAEMSGGTFTITNVGVFGVDSGTPIINPGESAILAFGAVRKQPWVVETDGQDT 431
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPAT 640
+V R + +AL +DHR IDG + FL + E + DPAT
Sbjct: 432 IVPRQICTLALAFDHRHIDGEKGSRFLADVAEIMADPAT 470
>UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Pyrobaculum aerophilum|Rep: Pyruvate dehydrogenase E2 -
Pyrobaculum aerophilum
Length = 383
Score = 130 bits (313), Expect = 5e-29
Identities = 68/213 (31%), Positives = 124/213 (58%), Gaps = 2/213 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+++ A+ E+D + ++ R++ + +K I+L L+ KA A AL
Sbjct: 167 VAEKMSKAKRLIPHAYHLEEVDFTELIKLRER-VKAEAEKRGIRLTLLPFIAKAVAMALR 225
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P++N+ +E N I+ + V++ + V T +GLVV V++N ++ I LA+K
Sbjct: 226 EYPMLNSEYDEEKNAIVVKKEVNLGIGVDTEQGLVVVVVKNADKKGLLEMAKEINELAQK 285
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR GKL ++++ G TFTISN G G L G I+N P++ IL + ++P A+ ++ IR
Sbjct: 286 AREGKLELQDVRGSTFTISNIGAVGGLGGLSILNYPEAGILAVGQARKKPWAVGDRIEIR 345
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+ +A+++DHR++DG F+ ++KE +E+P
Sbjct: 346 DIALLAVSFDHRVVDGAYVARFMNRVKELLENP 378
>UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex, E2
component, dihydrolipoamide succinyltransferase; n=2;
Lactobacillales|Rep: Acetoin/pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
succinyltransferase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 431
Score = 129 bits (312), Expect = 6e-29
Identities = 78/212 (36%), Positives = 111/212 (52%), Gaps = 3/212 (1%)
Frame = +2
Query: 11 RLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQP 190
R D Q +T F+ +D+ ++ RK + I+L ++ VKA A P
Sbjct: 214 RAMDRQAAIPTVTNFDSVDVRKLVGHRKAFKEMARDDKGIRLTYLAYAVKALAAVAKKFP 273
Query: 191 VVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKART 364
+NA ++ EI+Y D V++ +AV P GL VPVI+N + I I LAE R
Sbjct: 274 ELNASVDMKAQEIVYHDDVNMGIAVDAPTGLFVPVIKNADRKSIFTIAQEITDLAEAVRD 333
Query: 365 GKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIRPM 541
G +T +M GGT TISN G TPIIN + AILG+ I + PI +G++ +
Sbjct: 334 GSITPAQMQGGTITISNLGSARGTWFTPIINGKEVAILGLGSILKEPIVNDDGELAVGQN 393
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPA 637
M ++LTYDHRLIDG L +K+ + DPA
Sbjct: 394 MKLSLTYDHRLIDGMLGQSALNYLKQLLSDPA 425
>UniRef50_A4XEQ9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Sphingomonadaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 480
Score = 129 bits (312), Expect = 6e-29
Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 1/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+RL +A+ T + +M RK T K + VKA A AL+
Sbjct: 268 VARRLTEAKQTIPHFYLRVSASVDALMDLRK----TANLVLGTKASINDYLVKAVALALV 323
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN + + + + D+++AVA+PKGLV P++R M A I T L +KA+
Sbjct: 324 RHPDVNVQVHGDSVHSFPHADVAIAVASPKGLVTPIVRQADRMHIAQIAATTRALIDKAQ 383
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPI-ALNGQVVIRP 538
G+L E+MDGGTF++SN G+FG IINPPQ AIL + G+ + A NG +
Sbjct: 384 AGRLGYEDMDGGTFSVSNLGMFGIEQFDAIINPPQGAILAVGGVNRVAVEAANGDIAFEN 443
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVA 649
+ + ++ DHR IDG FL+ +K +E P + A
Sbjct: 444 RIQLTMSVDHRAIDGAAGAKFLQTLKGLLEAPEGLFA 480
>UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=11;
Proteobacteria|Rep: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX - Brucella
melitensis
Length = 421
Score = 129 bits (311), Expect = 8e-29
Identities = 74/215 (34%), Positives = 117/215 (54%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +A+ T + ++ ++A R + + ++ S ++ + +KA+A AL
Sbjct: 208 IARRLLEAKTTVPHFYLNVDCEIDALLALRSQINEK--REGSARISVNDFVIKASAAALR 265
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P N + + ++ VDI+VAVAT GL+ P+IR+ M+ I + LA +AR
Sbjct: 266 RVPDANVIWTDEALLKLKDVDIAVAVATEGGLITPIIRSADQMSLGAISAQMKSLAARAR 325
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
+L EE GG F+ISN ++G + IINPPQSAIL + RPI NG++ M
Sbjct: 326 ENRLKPEEFQGGGFSISNLSMYGVKSFSAIINPPQSAILAVGAGERRPIERNGELAFATM 385
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M + L+ DHR +DG L K G+EDP +++
Sbjct: 386 MSVTLSVDHRAVDGALGAQLLAAFKAGIEDPMSLL 420
>UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=1;
Propionibacterium acnes|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Propionibacterium acnes
Length = 469
Score = 129 bits (311), Expect = 8e-29
Identities = 71/218 (32%), Positives = 129/218 (59%), Gaps = 6/218 (2%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A+ +KD+ +T A++T F D++ M + L + +++ ++ + KA A+
Sbjct: 249 AKAVKDSLDTKALVTAFLTCDVTPTMELVNR-LRADRRFKGLRVSPLTVWCKAVCLAMGR 307
Query: 185 QPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P++NA ++ ++I++RD++++ +A ATP+GL+VPV+R+ Q+M ++ I + A
Sbjct: 308 TPIINAAWDDAADQIVFRDHINLGIAAATPRGLMVPVVRDAQDMAMLELATEITRIVAIA 367
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL----NGQV 526
+ KL + GTF+I+N GVFG GTP++N +SAIL + + RP + + +V
Sbjct: 368 KEDKLQPPDYADGTFSITNVGVFGLDAGTPVVNRTESAILVLGALARRPWVVGTGDDERV 427
Query: 527 VIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPAT 640
V R + ++L +DHRLIDG + FL + E + DPA+
Sbjct: 428 VPRWVTTMSLGFDHRLIDGEQGSTFLHDVAEILSDPAS 465
>UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Halobacteriaceae|Rep: Dihydrolipoamide
S-acetyltransferase component of pyruvate dehydrogenase
complex E2 - Haloarcula marismortui (Halobacterium
marismortui)
Length = 540
Score = 128 bits (310), Expect = 1e-28
Identities = 78/217 (35%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I + ++ T +T +E+D++ ++ R L + I+L M +KA A AL
Sbjct: 319 IGAAMTSSKYTAPHVTHQDEVDVTALVDARST-LRREAEAQDIRLTYMPFVMKACAAALQ 377
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P VN ++E EI+ + Y +I VA AT GL+VPV+ NV ++ +K
Sbjct: 378 ENPQVNVSLDEANEEIVEKQYYNIGVATATDDGLLVPVVENVDAKGLLEVASETNEKTQK 437
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP--IALNGQVV 529
AR L+ EEM GGTFTISN G G GTPIIN P+SAIL + I ++P + +G+
Sbjct: 438 ARERSLSPEEMRGGTFTISNIGGIGGEYGTPIINQPESAILALGEIKKKPRVVEADGEET 497
Query: 530 IRP--MMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
I P +M ++L++DHR++DG +A F I++ +++P
Sbjct: 498 IEPRHIMTLSLSFDHRVLDGADAAQFTNSIQKYLQNP 534
>UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=6; Bilateria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Caenorhabditis elegans
Length = 507
Score = 128 bits (310), Expect = 1e-28
Identities = 82/221 (37%), Positives = 122/221 (55%), Gaps = 6/221 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKH---LDTFTKKHSIKLGLMSPFVKAAAN 172
IA+RL ++++T +EI + ++ R+K L T + K+ + +KA+A
Sbjct: 287 IAKRLTESKSTIPHYYLTSEIQLDTLLQVREKLNGLLAKGTSGQATKISINDFIIKASAL 346
Query: 173 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAE 352
A P N+ ++ I +VD+SVAV+TP GL+ P+I N A I I LA+
Sbjct: 347 ACQRVPEANSYWMDSFIRENHHVDVSVAVSTPAGLITPIIFNAHAKGLATIASEIVELAQ 406
Query: 353 KARTGKLTIEEMDGGTFTISNGGVFGSLMG-TPIINPPQSAILGMHGIFER--PIALNGQ 523
+AR GKL E GGTFT+SN G+FGS+ T IINPPQS IL + G ++ P G
Sbjct: 407 RAREGKLQPHEFQGGTFTVSNLGMFGSVSDFTAIINPPQSCILAIGGASDKLVPDEAEGY 466
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
I+ M + L+ DHR +DG ++LR KE +E P T++
Sbjct: 467 KKIKTMK-VTLSCDHRTVDGAVGAVWLRHFKEFLEKPHTML 506
>UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4;
Actinomycetales|Rep: Dehydrogenase subunit - Frankia sp.
(strain CcI3)
Length = 430
Score = 128 bits (309), Expect = 1e-28
Identities = 68/181 (37%), Positives = 110/181 (60%), Gaps = 6/181 (3%)
Frame = +2
Query: 131 KLGLMSPFVKAAANALMDQPVVN-AVIEENE-----IIYRDYVDISVAVATPKGLVVPVI 292
++GL++ + AL+ P +N AV+ + + + + V + A TP+GLVVPV+
Sbjct: 250 RIGLLAILARICVAALVRFPALNSAVVTDADGRATGVRHHAAVHLGFAAQTPRGLVVPVV 309
Query: 293 RNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSA 472
+ Q +T A + IA L AR G LT E+ GGTFT++N GVFG TPII+ P++A
Sbjct: 310 HHAQGLTTARLAAEIARLTAAARAGTLTPAELTGGTFTLNNYGVFGVDGSTPIIHHPEAA 369
Query: 473 ILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAG 652
++G+ I RP A++G++ +R ++ ++ T+DHR+ DG A FLR + + VEDP ++
Sbjct: 370 MIGIGRIVPRPWAVDGELAVRRIVQLSFTFDHRVCDGATAGSFLRFVADAVEDPTVLLRH 429
Query: 653 L 655
L
Sbjct: 430 L 430
>UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue
acetyltransferase; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase -
Pedobacter sp. BAL39
Length = 549
Score = 128 bits (309), Expect = 1e-28
Identities = 77/215 (35%), Positives = 117/215 (54%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL ++ T IDM +A R K ++ F +K+ +KA A AL
Sbjct: 338 IAKRLSESLFTAPHFYLTMSIDMDGAIAARTK-INEFAP---VKISFNDMVLKAVAIALK 393
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN+ ++I Y ++V+I VAVA GL+VPV+R + + I + A++A+
Sbjct: 394 QHPAVNSSWLGDKIRYNEHVNIGVAVAVEDGLLVPVVRFADGKSLSHISAEVKDFAQRAK 453
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KL + +G TFTISN G+FG T IINPP + IL + GI + P+ NG VV +
Sbjct: 454 AKKLQPADWEGSTFTISNLGMFGIDEFTAIINPPDACILAIGGISQVPVVKNGAVVPGNV 513
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M + L+ DHR++DG FL+ K +E+P ++
Sbjct: 514 MKVTLSCDHRVVDGATGSAFLQTFKSLLEEPVRLL 548
>UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative; n=2;
Chlamydiales|Rep: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative - Chlamydia
muridarum
Length = 428
Score = 128 bits (308), Expect = 2e-28
Identities = 67/176 (38%), Positives = 105/176 (59%), Gaps = 2/176 (1%)
Frame = +2
Query: 125 SIKLGLMSPFVKAAANALMDQPVVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPVIRN 298
+IKL + V+A A AL + P +N+ +N II +DIS+AVA P G++ P+IR
Sbjct: 251 NIKLSINDCIVRACALALKEFPEINSGFNSVDNTIIRFSTIDISIAVAIPDGVITPIIRC 310
Query: 299 VQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAIL 478
I I GLA +AR L EE GG+F ISN G+ G T I+NPPQ+AIL
Sbjct: 311 ADRKNVGTISAEIKGLAARARQFSLKEEEYKGGSFCISNLGMTGISDFTAILNPPQAAIL 370
Query: 479 GMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ + E+P+ LNG++ + + L+ DHR+IDG A +F++++++ +E P+ ++
Sbjct: 371 AVGSVEEQPVVLNGELAVGSTCMLTLSVDHRVIDGYPAAMFMKRLQKLLEAPSVLL 426
>UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
AceF protein - Wigglesworthia glossinidia brevipalpis
Length = 496
Score = 128 bits (308), Expect = 2e-28
Identities = 71/198 (35%), Positives = 117/198 (59%), Gaps = 2/198 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI--EEN 217
+T F ++D+S + +FRK +T K+ +K+ ++S +K+ AL + P+ N+ + ++N
Sbjct: 295 VTQFEQVDISELESFRKNQNNTL--KYKVKITILSFIIKSVFFALKEYPLFNSSLSKDKN 352
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
++I + Y +I +AV+T GLVVPVI +V +I + ++ KAR KL +M GG
Sbjct: 353 KLILKKYFNIGIAVSTDYGLVVPVIFDVDKKGIIEISHELFNISNKARNKKLISRDMTGG 412
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
FTISN G G TPIIN P+ AILG+ +P+ + M+ ++L+YDHR+I
Sbjct: 413 CFTISNLGGIGGREFTPIINYPEVAILGVSQASIQPMWNGSSFSPKLMLPLSLSYDHRVI 472
Query: 578 DGREAVLFLRKIKEGVED 631
DG E F+ +K+ + D
Sbjct: 473 DGSEGAKFIIFLKKIISD 490
>UniRef50_A0LSF1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 449
Score = 128 bits (308), Expect = 2e-28
Identities = 68/173 (39%), Positives = 99/173 (57%)
Frame = +2
Query: 131 KLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNM 310
K+ L VK AA AL P VN +++ ++ I VAVA P GL+VPVIR+ +
Sbjct: 277 KISLNDLIVKVAAAALRKHPEVNVSYAGEKLLQHKHIHIGVAVAIPDGLIVPVIRDADTL 336
Query: 311 TYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHG 490
+I LA +AR GKL +++ G TFTISN G+FG T +INPP++AIL +
Sbjct: 337 GIREISQRTRDLATRARQGKLKPDDIGGSTFTISNLGMFGVDQFTAVINPPEAAILAVGA 396
Query: 491 IFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVA 649
+ E P+ +GQ+ + +M I L+ DHR +DG A FL + +E+P +A
Sbjct: 397 VREVPVVRDGQLAVGKVMTITLSIDHRALDGATAAGFLADLVTLLENPLAALA 449
>UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Acetyltransferase -
Chlamydia trachomatis
Length = 429
Score = 127 bits (307), Expect = 2e-28
Identities = 65/179 (36%), Positives = 107/179 (59%), Gaps = 2/179 (1%)
Frame = +2
Query: 116 KKHSIKLGLMSPFVKAAANALMDQPVVNAVIE--ENEIIYRDYVDISVAVATPKGLVVPV 289
++ +IKL + V+A A AL + P +N+ +N+II +DIS+AVA P G++ P+
Sbjct: 249 QEQNIKLSINDCIVRACALALKEFPEINSGFNSVDNKIIRFSTIDISIAVAIPDGVIAPI 308
Query: 290 IRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQS 469
+R I I GLA KA+ L EE GG+F +SN G+ G T I+NPPQ+
Sbjct: 309 VRCADRKNIGMISAEIKGLATKAKQQSLAEEEYKGGSFCVSNLGMTGISDFTAILNPPQA 368
Query: 470 AILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
AIL + + E+P+ LNG++ + + L+ DHR+IDG A +F+++++ +E P+ ++
Sbjct: 369 AILAVGSVEEQPVVLNGELAVGLTCMLTLSVDHRVIDGYPAAMFMKRLQRLLEAPSVLL 427
>UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2
component, putative; n=2; Streptococcus|Rep:
Dihydrolipoamide acetyl transferase, E2 component,
putative - Streptococcus sanguinis (strain SK36)
Length = 419
Score = 127 bits (307), Expect = 2e-28
Identities = 76/218 (34%), Positives = 124/218 (56%), Gaps = 3/218 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKK-HSIKLGLMSPFVKAAANAL 178
IA+R+ ++ +A +T ++D+S ++AFR+ T + ++ + + KA A AL
Sbjct: 202 IAERMMNSLQASAQVTLHRKVDISRLIAFRQDMKGKVTSPLENGEISITTLLTKAVAKAL 261
Query: 179 MDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
D P +NA + + + I +A A GLVVPVIR+V +T AD+ L I A +A
Sbjct: 262 KDHPQLNAWYFNGQYQEVEDIHIGIATALSDGLVVPVIRHVDKLTLADLGLAIKTEANQA 321
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN--GQVVI 532
R G L G TF+I+N G G TPI+N P+ AILG+ G + +AL+ GQV
Sbjct: 322 RKGTLDPALYSGSTFSITNLGGAGIEYFTPILNTPEVAILGV-GALQTSLALDSQGQVYE 380
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ ++ ++LT+DH+++DG+ A FL + + +E P +V
Sbjct: 381 QKLLPLSLTFDHQVVDGQPAAEFLASLADKLESPYDLV 418
>UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component; n=1; Mycoplasma
penetrans|Rep: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component - Mycoplasma
penetrans
Length = 478
Score = 126 bits (305), Expect = 4e-28
Identities = 70/214 (32%), Positives = 119/214 (55%), Gaps = 2/214 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA +K + + A EID++ + R K D + ++KL L+ +KA A L
Sbjct: 261 IANAMKRSWSNAAYTNLSVEIDVTDVWEQRNKIKDYILETENVKLNLLPFIIKAIAKTLK 320
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P+ NA+ ++ +I R+ V+I +AV T GL+VP I+N ++ +I +IA +A +
Sbjct: 321 QFPIFNAINDDANGTLILRNEVNIGIAVDTKDGLIVPNIKNADKLSIIEIAKSIADIAAR 380
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
ART K+T+ ++ GTF++SN G G G P+IN P+ AI G+ + + Q+V R
Sbjct: 381 ARTKKITMADLQKGTFSVSNYGSLGIEFGVPVINYPEVAIAGLGTASNKIKKVGIQMVER 440
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPA 637
+M + + DHR +DG + F ++K+ +E+ A
Sbjct: 441 KVMVLTIAADHRWVDGGDIARFANQVKQYLENIA 474
>UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=62; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Escherichia coli
(strain K12)
Length = 630
Score = 126 bits (305), Expect = 4e-28
Identities = 73/204 (35%), Positives = 116/204 (56%), Gaps = 3/204 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTK-KHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN- 217
+T F++ D++ + AFRK+ + K K +K+ + +KA A AL P N+ + E+
Sbjct: 426 VTHFDKTDITELEAFRKQQNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDG 485
Query: 218 -EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 394
+ + Y++I VAV TP GLVVPV ++V ++ + +++KAR GKLT EM G
Sbjct: 486 QRLTLKKYINIGVAVDTPNGLVVPVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQG 545
Query: 395 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 574
G FTIS+ G G+ PI+N P+ AILG+ P+ + V R M+ I+L++DHR+
Sbjct: 546 GCFTISSIGGLGTTHFAPIVNAPEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRV 605
Query: 575 IDGREAVLFLRKIKEGVEDPATIV 646
IDG + F+ I + D +V
Sbjct: 606 IDGADGARFITIINNTLSDIRRLV 629
>UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Leptospira|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2 -
Leptospira interrogans
Length = 458
Score = 126 bits (304), Expect = 6e-28
Identities = 70/217 (32%), Positives = 112/217 (51%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RL + +T E+D + + R + + S K+ L +KA + +L
Sbjct: 242 IASRLAHSTSTIPHFYLTLELDATPLDTLRNSYNKDLKLEGSSKISLNDLIIKACSLSLK 301
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P VN+ E+ I+ +DI VAV+ GL+ P IRN + ++I I LA +AR
Sbjct: 302 EVPEVNSSWREDHILEHGRIDIGVAVSIEGGLITPYIRNADQKSVSEIGREIKELASRAR 361
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KL E GTFT+SN G+FG T +IN P++AIL + + E+P+ G +V+
Sbjct: 362 ERKLKPAEYTDGTFTVSNLGMFGISSFTAVINEPEAAILAVGALVEKPVLKEGSIVVGKT 421
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAG 652
+ + L+ DHR++DG FL ++ E P ++ G
Sbjct: 422 LNVTLSCDHRVVDGATGARFLSSFRDYTEYPLRLLTG 458
>UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component
dihydrolipoamide acetyltransferase; n=6; Mycoplasma|Rep:
Pyruvate dehydrogenase E2 component dihydrolipoamide
acetyltransferase - Mycoplasma mobile
Length = 453
Score = 126 bits (304), Expect = 6e-28
Identities = 70/213 (32%), Positives = 116/213 (54%), Gaps = 2/213 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ +K++ + A NEI++ +++ R+K D+ +K+ + +KA AL
Sbjct: 235 IAKAMKNSWSNVAYTNLVNEINVGSLVSLREKIKDSVQDLTGVKVTFLPFIIKAITLALK 294
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ PV+ A +E +E++Y ++I +AV T GL+VPVI+N + +I I LA
Sbjct: 295 EFPVLMAKYDEQASELVYSGTLNIGIAVDTEAGLMVPVIKNADKLNIIEIAKEITRLAVA 354
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR K+ +E+ G FT++N GSL G P+IN P AI G+ I + PI +V
Sbjct: 355 ARDKKIKADELKGSDFTVTNYASVGSLFGIPVINYPDMAIAGIGVIKDEPIVTKNGIVAG 414
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+M + + DHR +DG F +K+K +E+P
Sbjct: 415 KIMNLTVAADHRWVDGATIGRFAQKVKHFLENP 447
>UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Salinibacter ruber DSM 13855|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Salinibacter ruber
(strain DSM 13855)
Length = 465
Score = 126 bits (304), Expect = 6e-28
Identities = 76/217 (35%), Positives = 116/217 (53%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++ + +ID+ + R+ D ++ K+ KA A +L
Sbjct: 248 IARRLAESKYSAPHYYLTVDIDVERAIEVREDLNDLAEEQGRAKISFNDFITKACALSLH 307
Query: 182 DQPVVNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
D P VNA +E EI + V I +AVA +GL+ PVIR+ +++ LAE+
Sbjct: 308 DHPYVNAAYRPDEGEIHKHNRVHIGIAVAIDEGLITPVIRDADRKGLSELARETRALAER 367
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR L EE +G TFT SN G+FG T IINPP SAIL + I + P+ +G+VV
Sbjct: 368 ARDRDLEPEEFEGATFTTSNLGMFGIEEFTAIINPPNSAILAIGEIRDTPVVEDGEVVPG 427
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M + L+ DHR++DG + FL +K +E+P ++
Sbjct: 428 KRMKVTLSCDHRVVDGAKGAHFLDTVKSYLEEPMNLL 464
>UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex (E2)
protein; n=1; Nitrosomonas europaea|Rep: AceF;
dihydrolipoamide acetyltransferase component of pyruvate
dehydrogenase complex (E2) protein - Nitrosomonas
europaea
Length = 453
Score = 125 bits (302), Expect = 1e-27
Identities = 73/190 (38%), Positives = 108/190 (56%), Gaps = 4/190 (2%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIE---- 211
+T F+E D++ + A RK H +T + + KL +++ +KA AL P NA ++
Sbjct: 249 VTQFDEADVTDLEALRKNHNET-RQNNGTKLTILAFLIKAVTAALKKFPEFNASLDNSTT 307
Query: 212 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 391
E+++I + Y + A TP GLVVPVIR+ I + L+ AR GKL +M
Sbjct: 308 ESQLIIKRYYHLGFAADTPNGLVVPVIRDADQKGVIGIAEELTRLSSLAREGKLKPGDMQ 367
Query: 392 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 571
G +FTIS+ G G TPIIN P+ AILG+ +P+ NGQ V R ++ ++L+YDHR
Sbjct: 368 GASFTISSLGGIGGTGFTPIINAPEVAILGVSRASLKPVYQNGQFVPRLVLPLSLSYDHR 427
Query: 572 LIDGREAVLF 601
+IDG A F
Sbjct: 428 VIDGASAARF 437
>UniRef50_A5V4B2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Sphingomonas wittichii
RW1|Rep: Catalytic domain of components of various
dehydrogenase complexes - Sphingomonas wittichii RW1
Length = 420
Score = 125 bits (302), Expect = 1e-27
Identities = 79/216 (36%), Positives = 119/216 (55%), Gaps = 6/216 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQ + ++ +T E D + IMA R+KH F + + L + F+ A A+
Sbjct: 203 IAQNMLNSVTVAPHVTAMFECDFTAIMAHRRKHKAAFAAEGA-NLTFTAYFIAACVAAMK 261
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVAT-PKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P +N+ ++ + D V+I + A KGLVVPV+ Q ++ I + + E+A
Sbjct: 262 AAPAINSRWHDDRLDIFDDVNIGIGTALGDKGLVVPVVSKCQELSLLGIAKRLTEMVERA 321
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTP-IINPPQSAILGMHGIFERPIA--LNG--Q 523
R KLT +M GGTFTISN GV GSL TP IIN PQSAILG+ +R + ++G
Sbjct: 322 RANKLTPADMRGGTFTISNHGVSGSLFATPIIINQPQSAILGIGKTEKRVVVREVDGVDT 381
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
+ IR + Y++LT DHR++DG + +L E +E+
Sbjct: 382 IQIRSLAYVSLTIDHRVVDGHQTNGWLSAFVETLEN 417
>UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2; unclassified
Gammaproteobacteria|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - marine gamma
proteobacterium HTCC2143
Length = 568
Score = 125 bits (302), Expect = 1e-27
Identities = 69/189 (36%), Positives = 114/189 (60%), Gaps = 2/189 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 217
+T F++ ++S + FR+ L ++ +K+ + +KA A AL + P NA + +
Sbjct: 366 VTQFDDANISDLEEFRQS-LKAEAERRGVKITPLPFLLKACAAALRENPKFNASLHTSGH 424
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
+++Y+ YV+I +AV TP GLVVPVIR+V + ++ +A+KA+ KL I++M GG
Sbjct: 425 QLVYKQYVNIGIAVDTPLGLVVPVIRDVDKKSIWELAAETVEMAQKAKDRKLKIDDMQGG 484
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
FT+S+ G G TPIIN P+ AILG+ + +P+ + V M+ ++L+YDHR I
Sbjct: 485 CFTVSSLGNIGGQGFTPIINVPEVAILGVSKLSVKPLWNGTEFVPAKMLPLSLSYDHRAI 544
Query: 578 DGREAVLFL 604
+G +A FL
Sbjct: 545 NGGDAGRFL 553
>UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component,
dihydrolipamide acetyltransferase; n=4; Geobacter|Rep:
Dehydrogenase complex E2 component, dihydrolipamide
acetyltransferase - Geobacter sulfurreducens
Length = 418
Score = 125 bits (301), Expect = 1e-27
Identities = 62/164 (37%), Positives = 102/164 (62%)
Frame = +2
Query: 155 VKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELT 334
+KAAA AL+ P +NA + ++ V+I AVA +GL VPV++ Q++ +I L
Sbjct: 254 LKAAALALVQFPRMNASFRDGGVVAHREVNIGFAVAMEEGLQVPVVKGCQSLALKEIALQ 313
Query: 335 IAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL 514
LAE+AR+G +T EE+ GGTF++SN G++G +I PPQ+AIL + + +RP+
Sbjct: 314 TVRLAERARSGAITQEEISGGTFSVSNLGMYGIDEFAAVIMPPQAAILAVGAVADRPVVR 373
Query: 515 NGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+GQ+ + M L+ DHR++DG A FL +++ +E+P ++
Sbjct: 374 DGQLAVARTMRATLSCDHRVVDGAYAAQFLGELRRVLENPVLML 417
>UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Pyruvate
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Neorickettsia sennetsu (strain
Miyayama)
Length = 403
Score = 125 bits (301), Expect = 1e-27
Identities = 71/215 (33%), Positives = 115/215 (53%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQRL +++ + H+++ +KK D K ++ +KA A AL
Sbjct: 193 IAQRLVESKQNVPHFYLSVTCYLQHLLSAKKKFYDCLETKVTVN----DFVIKACAFALD 248
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +N E I +DISVAVA P GL+ P++ + ++ + I + L +KA+
Sbjct: 249 KNPAMNVSWEGEFIRQNQTIDISVAVAIPDGLITPIVFSADKLSLSSISDEVRELVDKAK 308
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G+L E GG+FT+SN G++G T IINPPQ+AIL + + P VV+ +
Sbjct: 309 AGRLQPREFQGGSFTVSNLGMYGIDEFTAIINPPQAAILAVGAARKVPTVSADAVVVSDV 368
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ + L+ DHR+IDG A F++ +K+ +EDP ++
Sbjct: 369 VTLTLSCDHRVIDGALAARFMQSLKKAIEDPVIML 403
>UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2
component; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Dihydrolipoamide
acyltransferase E2 component - Candidatus Sulcia
muelleri str. Hc (Homalodisca coagulata)
Length = 371
Score = 125 bits (301), Expect = 1e-27
Identities = 72/215 (33%), Positives = 118/215 (54%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I++RL +++ + + F E+ M +++ R + KK+ K+ VKA+A A+
Sbjct: 159 ISKRLINSKIESPHYSLFIEVIMDNLIKLRDSINE---KKYLDKISFNDLIVKASALAIK 215
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P +N+ E I+Y + ++I +AVA GL+VPVI V + I I KA+
Sbjct: 216 ENPKINSSWTEKSILYHNNINIGIAVALEDGLIVPVINQVNEKSLRQISFEIKEKVIKAK 275
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
K+ E++G TFT+SN G+FG T IIN P S IL + I ++PI N ++VI
Sbjct: 276 EKKIQSNELEGSTFTVSNLGMFGIDSFTSIINQPNSCILSVGSIKKKPIINNDKIVIGHT 335
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
LT DHR+IDG +L+ +K+ +++P I+
Sbjct: 336 TKFTLTCDHRIIDGAVGSDYLKSLKKLLQEPLNII 370
>UniRef50_Q15U82 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Gammaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Pseudoalteromonas atlantica (strain T6c /
BAA-1087)
Length = 555
Score = 124 bits (300), Expect = 2e-27
Identities = 76/221 (34%), Positives = 125/221 (56%), Gaps = 3/221 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+++K + +T T EI M ++A R + D F+++ +KL M F+KA + AL
Sbjct: 335 MARQMKHSVSTIPHFTVSEEIQMDALIALRSQLKDDFSEQ-GVKLSFMPFFIKALSLALK 393
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
PV+N+ + ++ ++ Y + +I AV GL+VP I+ VQ+M+ DI + L E+
Sbjct: 394 AYPVINSQVNDDCTQLTYFNEHNIGFAVDGKLGLMVPNIKGVQDMSIFDIAKRASELIEQ 453
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVI 532
AR G+L ++ GGT +ISN GV G + TP+IN P++AI+ + I P N QV
Sbjct: 454 AREGRLRTADISGGTISISNIGVLGGTVATPVINHPEAAIVALGKIQRLPRFDENDQVRA 513
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
+M+++ + DHR+IDG V F K +E P ++ L
Sbjct: 514 VNIMHVSWSGDHRIIDGATMVRFNNLWKSYIEQPIKMLGTL 554
>UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Frankia|Rep: Biotin/lipoyl
attachment:Catalytic domain of components of various
dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
Length = 475
Score = 124 bits (299), Expect = 2e-27
Identities = 58/136 (42%), Positives = 88/136 (64%)
Frame = +2
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
V + A TP+GLVVPV+R+ Q T A + + L AR G+LT E+ GGTFT++N
Sbjct: 337 VHLGFAAQTPRGLVVPVVRDAQGHTTASLAAEVTRLTAAARAGRLTPAELTGGTFTLNNY 396
Query: 419 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 598
GVFG TPI+N P+ A++G+ I RP A++G++ +R + ++ T+DHR+ DG A
Sbjct: 397 GVFGVDGATPIVNHPEVAMIGIGRILPRPWAVDGELAVRRITQLSFTFDHRVCDGATAGA 456
Query: 599 FLRKIKEGVEDPATIV 646
FLR + + VE+P T++
Sbjct: 457 FLRFVADAVENPTTLL 472
>UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Actinomycetales|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 417
Score = 124 bits (299), Expect = 2e-27
Identities = 63/173 (36%), Positives = 106/173 (61%), Gaps = 2/173 (1%)
Frame = +2
Query: 143 MSPFVKAAANALMDQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTY 316
+S KA AL + P +NA +E EI+ + YV++ +A ATP+GLVVP I+ Q+++
Sbjct: 245 LSLVAKAMIVALRENPSLNASWDEENQEIVTKHYVNLGIAAATPRGLVVPNIKEAQSLSL 304
Query: 317 ADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIF 496
++ I L AR+G+ ++ GGT +I+N GVFG GTPI+NP +SAIL + +
Sbjct: 305 LELCRAITELTATARSGRAEPAQLTGGTVSITNVGVFGVDAGTPILNPGESAILCLGSVT 364
Query: 497 ERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
RP ++ +R + +++++DHR++DG + FL + + DPA+++A L
Sbjct: 365 RRPWVHEDELAVRWVTTLSVSFDHRVVDGEQGSRFLSSVAAMLHDPASLLAHL 417
>UniRef50_A7HHV9 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Anaeromyxobacter
sp. Fw109-5
Length = 574
Score = 124 bits (299), Expect = 2e-27
Identities = 68/196 (34%), Positives = 112/196 (57%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEI 223
+T +E D++ + FR + L+ K +K+ L++ +KA AL P N+ +E +++
Sbjct: 374 VTQHDEADITELERFRVE-LNQERAKEGVKVTLLAFVLKACVAALRRFPEFNSSLEGDQL 432
Query: 224 IYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTF 403
+ + Y I A TP GLVVPV+++ +I +A LA+KAR GKL + +M GGTF
Sbjct: 433 VLKRYFHIGFAADTPGGLVVPVVKDADRKGVLEIARELAELAQKARDGKLQLADMQGGTF 492
Query: 404 TISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDG 583
++S+ G G TPIIN P+ AILG+ +P+ + R M+ ++L+YDHR++DG
Sbjct: 493 SVSSLGGIGGTAFTPIINAPEVAILGVSRSATKPVWDGERFAPRLMLPLSLSYDHRVVDG 552
Query: 584 REAVLFLRKIKEGVED 631
A F + + + D
Sbjct: 553 AAAARFTSHLAQLLAD 568
>UniRef50_A0LQU7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 546
Score = 124 bits (299), Expect = 2e-27
Identities = 70/179 (39%), Positives = 107/179 (59%), Gaps = 3/179 (1%)
Frame = +2
Query: 128 IKLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNV 301
IKL ++ KA AL P+VN+ ++ +EI+ R YV++ +A ATP+GLVVP I++
Sbjct: 368 IKLSPLTLTAKAVLLALRRYPLVNSYWDDASDEIVVRHYVNLGIATATPRGLVVPNIKDA 427
Query: 302 QNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILG 481
++ D+ I LA AR G+ + ++ GTFTI+N GVFG GTPIINP ++AIL
Sbjct: 428 DRLSLIDLARAINELAATAREGRTPLAQLRNGTFTITNVGVFGVDTGTPIINPGEAAILA 487
Query: 482 MHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP-ATIVAGL 655
+ + P + V R + + L++DHR+IDG FLR + +EDP A ++A +
Sbjct: 488 LGTVRRAPWLYHDAVQPRWVTTLGLSFDHRIIDGDLGSRFLRDVAAFLEDPGAALLAAV 546
>UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding protein
of pyruvate dehydrogenase complex) (Lipoyl-containing
pyruvate dehydrogenase complex component X) (E3-binding
protein) (E...; n=1; Apis mellifera|Rep: PREDICTED:
similar to Pyruvate dehydrogenase protein X component,
mitochondrial precursor (Dihydrolipoamide
dehydrogenase-binding protein of pyruvate dehydrogenase
complex) (Lipoyl-containing pyruvate dehydrogenase
complex component X) (E3-binding protein) (E... - Apis
mellifera
Length = 598
Score = 124 bits (298), Expect = 3e-27
Identities = 81/217 (37%), Positives = 118/217 (54%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++ T +I + I RK+ K I + + KA A+AL+
Sbjct: 380 IAKRLGESKITIPHSYATIDIKIDKINEIRKE-----LKADGINISINDFITKATAHALV 434
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ P +N + + ++II VDIS+AVA GL+ P++ + + DI I LAEKA+
Sbjct: 435 ECPFINTLYKNDQIIQMPRVDISIAVAIESGLITPIVFDATAKSILDISKNIKELAEKAK 494
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
TG+L EE GGTFTISN G+FG IIN PQ+AIL + E LN +
Sbjct: 495 TGQLKPEEFQGGTFTISNLGMFGIKHFRAIINLPQTAILAVGSGREE---LNAALQKVTK 551
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAG 652
M +L+YD R ID +A FL +K +EDP+ ++AG
Sbjct: 552 MSTSLSYDRRAIDEDQAADFLAVLKAMLEDPSFLIAG 588
>UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,
lipoamide acyltransferase; n=9; Chlamydiaceae|Rep: 2-oxo
acid dehydrogenase, E2 component, lipoamide
acyltransferase - Chlamydia muridarum
Length = 410
Score = 124 bits (298), Expect = 3e-27
Identities = 70/211 (33%), Positives = 116/211 (54%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA L+ + + ++D++ +M + F H +KL + S ++ A +L
Sbjct: 195 IASSLRQSSEEVPHASLVVDVDVTDLMNLISLERERFAAAHGVKLTITSFIIQCLAKSLE 254
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPK-GLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P++N ++ + I+ + V++ VAV K G+VVPVI N Q+ I +A L+ +A
Sbjct: 255 QFPLLNGSLDGDTIVLKKAVNVGVAVNLNKEGVVVPVIHNCQDRGLVSIAKALADLSSRA 314
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL-NGQVVIR 535
R KL E GG+ T++N G+ G+L+G PII P+ AILG+ I +R + + + IR
Sbjct: 315 RASKLDASEAKGGSVTLTNFGMTGALIGMPIIRYPEVAILGIGTIQKRVVVREDDSLAIR 374
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
MMY+ LT+DHR++DG FL +K +E
Sbjct: 375 KMMYVTLTFDHRVLDGIYGGEFLTALKNRLE 405
>UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=9;
Rickettsiales|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Wolbachia pipientis wMel
Length = 454
Score = 124 bits (298), Expect = 3e-27
Identities = 72/217 (33%), Positives = 120/217 (55%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDA-QNT-NAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANA 175
IAQRL ++ QN + LT ++D + K +++ + + + + + +KAAA +
Sbjct: 236 IAQRLTESKQNVPHFYLTVDCQVDK---LISLKNEINSADENNKVTINDL--IIKAAAFS 290
Query: 176 LMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P +N+ +N+I+ +DIS+AVA GL+ P+++N I + L +
Sbjct: 291 MKKFPDINSSWIDNKILRYSNIDISIAVALEDGLITPIVKNADKKGILSISKEVKDLVSR 350
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR+GKL EE GG FTISN G+FG + IINPPQS I+ + ++PI +N ++ I
Sbjct: 351 ARSGKLKPEEFQGGGFTISNLGMFGIKAFSAIINPPQSCIMAVGASKKQPIVMNEKIEIA 410
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+M + L+ DHR +DG FL K +E+P ++
Sbjct: 411 EIMTVTLSVDHRAVDGALGAKFLNAFKHYIENPLVML 447
>UniRef50_A6W003 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Marinomonas|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Marinomonas sp. MWYL1
Length = 414
Score = 124 bits (298), Expect = 3e-27
Identities = 80/217 (36%), Positives = 124/217 (57%), Gaps = 7/217 (3%)
Frame = +2
Query: 2 IAQRLKDAQ-NTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANAL 178
IA + D+ +T+ +T+ E+DM I+ RK F ++ +KL + F+ A+A A+
Sbjct: 196 IANHMVDSLLHTSPHVTSVFEMDMGRIIEHRKMCKMGF-EEAGVKLTFTAYFLAASAKAM 254
Query: 179 MDQPVVNAVIEENEIIYRDYVDISVAVAT-PKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
PVVN+ ++ + + ++I V A GL+VPV++ VQ +I + +K
Sbjct: 255 QKVPVVNSRFHDDCLEIFEDINIGVGTALGDDGLIVPVVKQVQEKNLFEIASALQQQTDK 314
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTP-IINPPQSAILGMHGIFERPIA--LNGQ- 523
AR GKL +M GTFTISN GV GSL TP IIN PQ AILG+ + +R + ++G+
Sbjct: 315 ARQGKLAAADMRDGTFTISNHGVSGSLFATPIIINQPQVAILGIGKLEKRAVVEEVDGED 374
Query: 524 -VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
+VIRP Y++L+ DHR +D + LFL E +E+
Sbjct: 375 TIVIRPKCYVSLSIDHRALDAYQTNLFLSHFVEVIEN 411
>UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Plesiocystis pacifica SIR-1|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Plesiocystis pacifica
SIR-1
Length = 436
Score = 124 bits (298), Expect = 3e-27
Identities = 72/211 (34%), Positives = 109/211 (51%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + A+ ++DM AFR + + K+ VKA A +L
Sbjct: 219 IARNMTKAKQETPHYYLTMDVDMEKAFAFRADFNEAVPE--GTKISFNDLIVKAVARSLR 276
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
D P VNA + ++ I R V++ +AVA GLVVPV+R + I L + AR
Sbjct: 277 DFPSVNASFDGDKAIIRGDVNVGIAVAVEDGLVVPVVRYADQKSLEAISRESKALGKSAR 336
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
L E+M GGTFT+SN G+FG +INP ++ IL + I RP+ G++VIR
Sbjct: 337 DKHLRPEDMSGGTFTVSNLGMFGIESFAAVINPGEAGILAVGAIESRPVVQGGELVIRKR 396
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
M + ++ DHR+ DG A +L K++ +E+P
Sbjct: 397 MKMTISADHRVTDGAVAAKWLTKVRGYLENP 427
>UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=4; Magnoliophyta|Rep:
Dihydrolipoyllysine-residue acetyltransferase component 1
of pyruvate dehydrogenase complex, mitochondrial
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 637
Score = 124 bits (298), Expect = 3e-27
Identities = 76/217 (35%), Positives = 123/217 (56%), Gaps = 7/217 (3%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++ L +++ + ++AFRK+ + H +K+ + +KA A AL
Sbjct: 419 IAKRLLESKQKIPHLYLQSDVVLDPLLAFRKE----LQENHGVKVSVNDIVIKAVAVALR 474
Query: 182 DQPVVNAV--IEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ NA E+ +I+ D VDIS+AVAT KGL+ P+I+N + + I L + LA+K
Sbjct: 475 NVRQANAFWDAEKGDIVMCDSVDISIAVATEKGLMTPIIKNADQKSISAISLEVKELAQK 534
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGM---HGIFERPIALNG-- 520
AR+GKL E GGTF+ISN G++ IINPPQ+ IL + + + E I L+G
Sbjct: 535 ARSGKLAPHEFQGGTFSISNLGMYPVDNFCAIINPPQAGILAVGRGNKVVEPVIGLDGIE 594
Query: 521 QVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
+ + M + L+ DHR+ DG+ F+ +++ ED
Sbjct: 595 KPSVVTKMNVTLSADHRIFDGQVGASFMSELRSNFED 631
>UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=5; Actinomycetales|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Leifsonia xyli
subsp. xyli
Length = 452
Score = 124 bits (298), Expect = 3e-27
Identities = 67/201 (33%), Positives = 113/201 (56%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEI 223
++ F ++D + M F K+ L + +K+ + KA A+ P VN+ + EI
Sbjct: 252 VSVFVDVDATRTMEFVKR-LKSAPDFVGVKVSPLLIMAKAIVWAVRRNPTVNSTWTDEEI 310
Query: 224 IYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTF 403
I R YV++ +A ATP+GL+VP ++ Q M+ ++ + L AR GK +M GT
Sbjct: 311 IVRHYVNLGIAAATPRGLIVPNVKEAQGMSLLELAGALEELTLTAREGKTQPADMANGTI 370
Query: 404 TISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDG 583
TI+N GVFG GTPI+NP + I+ + I ++P ++G+V R + + ++DHR++DG
Sbjct: 371 TITNIGVFGMDTGTPILNPGEVGIVALGTIKQKPWVVDGEVRPRFVTTLGGSFDHRVVDG 430
Query: 584 REAVLFLRKIKEGVEDPATIV 646
A FL + +E+PA ++
Sbjct: 431 DVASRFLADVASIIEEPALLL 451
>UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=42;
Bacteria|Rep: Dihydrolipoamide acetyltransferase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 548
Score = 123 bits (297), Expect = 4e-27
Identities = 69/186 (37%), Positives = 107/186 (57%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEI 223
+T +E D++ + A R + L+ +K +K +++ +KA AL P NA ++ + +
Sbjct: 348 VTNNDEADITELEALRVQ-LNKEHEKAGVKFTMLAFVIKAVVAALKKFPTFNASLDGDNL 406
Query: 224 IYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTF 403
+++ Y + A TP GLVVPVIR+ DI +A L++ AR GKL ++M GG F
Sbjct: 407 VFKQYYHVGFAADTPNGLVVPVIRDADKKGLVDIAKEMAELSKAARDGKLKPDQMQGGCF 466
Query: 404 TISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDG 583
+IS+ G G TPIIN P+ AILG+ +P+ Q V R + ++L+YDHR+IDG
Sbjct: 467 SISSLGGIGGTNFTPIINAPEVAILGLSRGQMKPVWDGKQFVPRLTLPLSLSYDHRVIDG 526
Query: 584 REAVLF 601
EA F
Sbjct: 527 AEAARF 532
>UniRef50_Q1LSX2 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Baumannia cicadellinicola str. Hc (Homalodisca
coagulata)|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Baumannia cicadellinicola subsp. Homalodisca coagulata
Length = 358
Score = 123 bits (296), Expect = 5e-27
Identities = 70/199 (35%), Positives = 115/199 (57%), Gaps = 3/199 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFT-KKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN- 217
+T F+E +++ + FRK+ T KK +IK+ L+ +KA + AL P+ N+ + E+
Sbjct: 154 VTQFHEANITKLEKFRKEQNSTEEIKKLNIKITLLIFVMKAVSKALEIFPLFNSSLSEDG 213
Query: 218 -EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 394
++I + Y++I +AV TP GL+VPV NV + + LA+KA TGKL +M
Sbjct: 214 TKLICKKYINIGIAVDTPSGLLVPVCHNVNKKGIITLSQEVINLAQKAHTGKLIPSDMQD 273
Query: 395 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 574
FTISN G G + TPIIN P+ AILG+ + +P+ + + ++ ++L+YDHR+
Sbjct: 274 SCFTISNLGNIGGMHFTPIINAPEVAILGVSKTYFKPVWNGEKFIPLQVLPLSLSYDHRV 333
Query: 575 IDGREAVLFLRKIKEGVED 631
I+G + F+ I + D
Sbjct: 334 INGGDGARFINFIGHIMSD 352
>UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Dihydrolipoamide S-succinyltransferase - Herpetosiphon
aurantiacus ATCC 23779
Length = 442
Score = 123 bits (296), Expect = 5e-27
Identities = 69/210 (32%), Positives = 112/210 (53%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A+R+ ++Q + I+M I A K + H KL + +KA A AL
Sbjct: 232 AKRMVESQQQVPPFFVTSTIEMDAIQALLPK----LREAHGGKLSVTELLLKACAIALKK 287
Query: 185 QPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKART 364
P +N+ ++++ V ISVAVAT GL+ PV+RN +++ I + + + R
Sbjct: 288 FPALNSTFAGDKLLVHKDVHISVAVATDAGLLAPVVRNCDSLSLGAISNQMRDVIGRTRD 347
Query: 365 GKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMM 544
GK ++++ GGTFT+SN G+F II PPQSAIL + P+ +G++VIR +M
Sbjct: 348 GKAGLDDLQGGTFTVSNLGMFDVTNFIAIITPPQSAILAVGSTIATPVVRDGEIVIRQLM 407
Query: 545 YIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+ ++ DHR DG FL ++K +++P
Sbjct: 408 NVTVSADHRATDGASVAQFLVELKNLLQNP 437
>UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Alphaproteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Sinorhizobium medicae WSM419
Length = 386
Score = 122 bits (294), Expect = 9e-27
Identities = 79/215 (36%), Positives = 120/215 (55%), Gaps = 6/215 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + ++ T +T E D S + R +H + + L + V A+ A+
Sbjct: 161 IAEHMLNSVMTAPHVTAVFEADFSAVTRHRDEHRKKLAAR-GVNLSYTAYVVLASLAAMR 219
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATP-KGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P VN+ E+ + D ++I V ++ KGLVVPVIR QN++ A+I I L +A
Sbjct: 220 AVPEVNSRWHEDALETFDDINIGVGISLGGKGLVVPVIRRAQNLSLAEIAARIQDLTTRA 279
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTP-IINPPQSAILGMHGIFERPIA--LNG--Q 523
R+ L+ ++ GGTFTISN GV GSL+ TP IIN PQSAILG+ + +R + ++G
Sbjct: 280 RSNALSPADVTGGTFTISNHGVSGSLLATPIIINQPQSAILGVGKLDKRVVVREVDGIDT 339
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
+ IRPM Y++LT DHR +DG +L + +E
Sbjct: 340 IQIRPMAYVSLTIDHRALDGHHTNAWLTEFVRVLE 374
>UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase, E2 component
- Alcanivorax borkumensis (strain SK2 / ATCC 700651 /
DSM 11573)
Length = 564
Score = 122 bits (293), Expect = 1e-26
Identities = 75/211 (35%), Positives = 118/211 (55%), Gaps = 2/211 (0%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
AQ L + T +T + D++ + AFRK + ++ +KL +++ V A A AL +
Sbjct: 349 AQNLTRSWLTIPHVTQHDNADITDLEAFRKSQ-NKRLEREGVKLTMLAFLVAACARALKE 407
Query: 185 QPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P N+ +E + +I + Y++I +AV TP GLVVPVI++ I + LAEKA
Sbjct: 408 YPRFNSSLENSGEALIEKRYINIGIAVDTPNGLVVPVIKDADKKGLKAIAQEMDELAEKA 467
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRP 538
R KLT +M GGTF+IS+ G G TPI+N P+ AILG+ +P+ + R
Sbjct: 468 RNRKLTPADMKGGTFSISSLGGIGGTAFTPIVNWPEVAILGVSRSDMQPVWDGSEFQPRL 527
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
++ ++L+YDHR+IDG A F + + + D
Sbjct: 528 ILPMSLSYDHRVIDGAAAARFTTYLSQLLTD 558
>UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 448
Score = 122 bits (293), Expect = 1e-26
Identities = 74/218 (33%), Positives = 118/218 (54%), Gaps = 2/218 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+R+ ++ + A LT + + I+A RKK + K+ L A + L+
Sbjct: 231 VAKRMMESLTSTAQLTLNTTANAAGILAMRKKVKNADEALGLNKITLNDLVCFAVSRTLL 290
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
PV NA +E+ + + V + A TP+GL+VPVIR+ Q + LA A
Sbjct: 291 KYPVFNAHLEDGVLTEFEQVHLGFACDTPRGLLVPVIRSAQALGLKAFSDEAKRLAGGAI 350
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRP 538
G L+ + + GGTFT+SN G FG TP+IN PQ+AILG+ I RP +A +G + +
Sbjct: 351 DGSLSPDFLSGGTFTVSNIGSFGIETFTPVINLPQTAILGVGAITPRPTVAADGSIGVEQ 410
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVED-PATIVA 649
+ ++LT DH++IDG + FLR + +E+ T++A
Sbjct: 411 RLNLSLTIDHQVIDGADGARFLRDLVAAIENIDVTVLA 448
>UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Alphaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Oceanicaulis alexandrii HTCC2633
Length = 437
Score = 122 bits (293), Expect = 1e-26
Identities = 68/217 (31%), Positives = 125/217 (57%), Gaps = 3/217 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + A+ T +T +EID++ + R H++ KL ++ V A +L
Sbjct: 219 IAENMAHAKRTIPHITYVDEIDLTALEDLRA-HMNAKKSDDQTKLTIIPFLVLALVKSLP 277
Query: 182 DQPVVNAVIEENE--IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P NA + + + D V +A ATP GL+VPVI++ +++ ++ + L +
Sbjct: 278 KFPQANAHFDTDGSLLTQHDGVHCGIAAATPNGLMVPVIKHAESLDIWEVAAEVKRLGDA 337
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVI 532
A+ GK T +E+ G T TI++ G G ++ TP+IN P++AI+G++ + P G+VV
Sbjct: 338 AKAGKATKDELTGSTITITSLGAIGGIVTTPVINHPETAIIGVNKMQTLPRYDEAGRVVP 397
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATI 643
+ +M ++ ++DHR++DG EA L ++++K +E+PAT+
Sbjct: 398 KKIMNLSSSFDHRIVDGYEAALLVQEMKGYLENPATL 434
>UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=14; Burkholderia|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Burkholderia pseudomallei
(Pseudomonas pseudomallei)
Length = 483
Score = 121 bits (292), Expect = 2e-26
Identities = 67/216 (31%), Positives = 120/216 (55%), Gaps = 2/216 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQR++DA+ + EID++ + A R + + +L ++ +A AL
Sbjct: 266 IAQRMQDAKRRIPHFSYVEEIDVTELEALRAELNRKYGDTRG-RLTVLPLLARAMVIALR 324
Query: 182 DQPVVNAVIEENEIIYRDY--VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P +NA ++ + + V + +A + GL+VPV+R+ + I +A LA+
Sbjct: 325 EFPQINARYDDEAGVVTRHGAVHLGIATQSKAGLMVPVVRHAEARDPWSIAAEVARLADA 384
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR G+ +E+ G T TI++ G G + TP+IN P+ I+G++ I ERP+ G VV R
Sbjct: 385 ARAGRAERDELSGSTITITSLGALGGIASTPVINSPEVGIVGVNRIVERPMFRGGAVVAR 444
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATI 643
+M ++ ++DHR+IDG +A F++ ++ +E PA +
Sbjct: 445 KLMNLSSSFDHRVIDGMDAAEFIQAVRGLLEQPALL 480
>UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=11; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Haemophilus
influenzae
Length = 567
Score = 120 bits (290), Expect = 3e-26
Identities = 71/204 (34%), Positives = 115/204 (56%), Gaps = 3/204 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTK-KHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN- 217
+T F++ D++ + AFRK+ K K +K+ + +KA A AL P N+ I E+
Sbjct: 363 VTHFDKADITDLEAFRKEQNALREKQKLGVKITPVVFIMKAVAKALEAYPRFNSSITEDA 422
Query: 218 -EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 394
+I + Y++I VAV TP GLVVPV +NV ++ + +++KAR GKLT +M G
Sbjct: 423 QRLILKKYINIGVAVDTPNGLVVPVFKNVNKKGIIELSRELMEVSKKAREGKLTASDMQG 482
Query: 395 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 574
G FTIS+ G G+ PI+N P+ AILG+ P+ + R ++ ++L++DHR+
Sbjct: 483 GCFTISSLGGIGTTHFAPIVNAPEVAILGVSKSSMEPVWNGKEFAPRLILPMSLSFDHRV 542
Query: 575 IDGREAVLFLRKIKEGVEDPATIV 646
IDG + F+ + + D +V
Sbjct: 543 IDGADGARFISYLGSVLADLRRLV 566
>UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=4; Acholeplasmataceae|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Acholeplasma
laidlawii
Length = 544
Score = 120 bits (290), Expect = 3e-26
Identities = 64/199 (32%), Positives = 114/199 (57%), Gaps = 2/199 (1%)
Frame = +2
Query: 56 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI--EENEIIY 229
+EI++ ++ FR + K IKL M+ KA AL + P+ NA + +E+
Sbjct: 345 DEINVDALVNFRNEAKGLAESK-GIKLTYMAFIAKAVLIALKEFPMFNASFNHDTDEVYI 403
Query: 230 RDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTI 409
+ ++++ +AV TP GL+VP I+N ++ ++ + LA+ K+++++ GGTFTI
Sbjct: 404 KKFINLGMAVDTPDGLIVPNIKNADRLSVFELASQVRSLADDTIARKISMDQQTGGTFTI 463
Query: 410 SNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGRE 589
+N G G GTP+IN P+ AILG+ I +P + ++ I + ++L DHR+IDG +
Sbjct: 464 TNFGSAGIAFGTPVINYPELAILGIGKIDRKPWVVGNEIKIAHTLPLSLAVDHRIIDGAD 523
Query: 590 AVLFLRKIKEGVEDPATIV 646
FL ++KE + +P ++
Sbjct: 524 GGRFLMRVKELLTNPTLLL 542
>UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid
dehydrogenase component; n=1; Nocardia farcinica|Rep:
Putative branched-chain alpha-keto acid dehydrogenase
component - Nocardia farcinica
Length = 510
Score = 120 bits (288), Expect = 5e-26
Identities = 72/219 (32%), Positives = 115/219 (52%), Gaps = 2/219 (0%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A + + T +TF +D + M HL T + L + KA AL +
Sbjct: 293 AAAMVTSATTIPQASTFVTVDCTATMELID-HLRTTPAFAGLSLTPLVVVAKAVLAALAE 351
Query: 185 QPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P VNA +E +I+ + YV + +A AT +GL+VP ++ ++ ++ I E A
Sbjct: 352 FPGVNAQWDEERQQIVTKRYVHLGIAAATDRGLLVPSVKEAHRLSLRELCAEIGRTIEAA 411
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRP 538
R G T ++ GGTFTI+N GVFG G P++NP ++AIL + I RP + ++ +R
Sbjct: 412 RAGTATPADLTGGTFTITNVGVFGVDSGVPLVNPGEAAILCLGAIGRRPWVVADELAVRW 471
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
+ + L++DHRLIDG A FL + + DP T+++ L
Sbjct: 472 VTTLGLSFDHRLIDGELAARFLATVAGLLTDPLTLLSRL 510
>UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzyme; n=1; Planctomyces maris DSM
8797|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzyme - Planctomyces maris DSM 8797
Length = 449
Score = 120 bits (288), Expect = 5e-26
Identities = 67/174 (38%), Positives = 103/174 (59%), Gaps = 2/174 (1%)
Frame = +2
Query: 131 KLGLMSPFVKAAANALMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQ 304
K+ + + +KA A AL + P N+ + +EI+Y++Y++I VAV T GLVVPV+++V
Sbjct: 273 KVTMTALAMKAIAIALHEYPSFNSSFDSQTDEIVYKNYINIGVAVDTENGLVVPVVKDVD 332
Query: 305 NMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGM 484
I + LA KAR +L + +M GGTFTI+N G G TPI+N P+ AILGM
Sbjct: 333 KKNIITIANEMNALAIKARDRRLEMNDMQGGTFTITNLGGLGGTSFTPIVNYPEVAILGM 392
Query: 485 HGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
LN V R M+ ++L+YDHR+I+G +A F+ ++ + DP ++
Sbjct: 393 SRSRHEFQLLNDSPVPRLMLPLSLSYDHRVINGADAARFIVRLSSLLSDPFNLL 446
>UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_3, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 628
Score = 119 bits (287), Expect = 6e-26
Identities = 74/216 (34%), Positives = 114/216 (52%), Gaps = 1/216 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RL +++ T + M ++ R++ K +K+ + +KA+A AL
Sbjct: 416 IAARLLESKTTIPHYYLTMTVTMDKVLKVREE----LNKLQKVKISVNDFIIKASALALK 471
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
D P N+ I DIS+AVAT GL+ P++ N + I T+ LA+KA+
Sbjct: 472 DVPQANSQWHGTYIRKFANADISIAVATDAGLITPIVFNAGSKGLGTIASTVKELADKAK 531
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIA-LNGQVVIRP 538
KL +E GGTFTISN G+FG +INPPQSAIL + +R + +GQ +
Sbjct: 532 ANKLKPQEFIGGTFTISNLGMFGIDQFIAVINPPQSAILAVGKTSKRFVPDEHGQPKVES 591
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M + L+ DHR++DG +L++ K +EDP T++
Sbjct: 592 QMDVTLSCDHRVVDGAVGAQWLQRFKYYIEDPNTLL 627
>UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep:
AceF - Mycoplasma gallisepticum
Length = 440
Score = 119 bits (286), Expect = 8e-26
Identities = 65/202 (32%), Positives = 119/202 (58%), Gaps = 4/202 (1%)
Frame = +2
Query: 38 AMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEE- 214
A + TFN D++ ++++RK+ D +++KL + +KA A++ P+ N+ ++
Sbjct: 235 ATVLTFN-FDVTKLVSYRKQVKDAVLASYNVKLSFLPFLLKAITKAVVAHPIFNSHYDKA 293
Query: 215 -NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 391
N ++ + +++ +AV T GL+VP I++ Q+ + ++ + LAEKAR+ K+ + ++
Sbjct: 294 SNRLVLKKKINLGIAVDTADGLMVPNIKSAQDKSVIELAREVNNLAEKARSKKIGLADLA 353
Query: 392 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL--NGQVVIRPMMYIALTYD 565
GT +++N G G+L GTPII P+ AI+ G E +A Q+VI+ +M I + D
Sbjct: 354 DGTISVTNFGSIGALFGTPIIKFPEVAIIAT-GTVEEKLARTPENQIVIKQIMPITIAAD 412
Query: 566 HRLIDGREAVLFLRKIKEGVED 631
HR IDG + F + +KE VE+
Sbjct: 413 HRWIDGADIGRFAKTLKEIVEN 434
>UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Putative
uncharacterized protein - Rhodobacterales bacterium
HTCC2654
Length = 472
Score = 119 bits (286), Expect = 8e-26
Identities = 76/216 (35%), Positives = 114/216 (52%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ L ++ T T +I++ +M RK ++ + K+ + +KA A AL
Sbjct: 258 IAKALVQSKQTVPHFYTTVDIEVDALMDLRKG-MNGSADEGDPKVSVNDFLLKACALALA 316
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN + + + + DI++AVA GL+ PV+RNV DI LA KAR
Sbjct: 317 KHPGVNVHVSDTGVTPFEQADIAMAVAIDGGLITPVVRNVGGRGLRDIAADAKALAGKAR 376
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
L+ +EM GGTFT+SN G+FG IINPPQ+AIL + G ++G V +
Sbjct: 377 DRALSGDEMTGGTFTLSNLGMFGVREFDAIINPPQAAILAVGGPRREAREVDGGVGFVSV 436
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVA 649
M + L+ DHR +DG A FLR ++ +E P +V+
Sbjct: 437 MSVTLSADHRAVDGALAAEFLRTLRGLIEAPLRLVS 472
>UniRef50_A0K281 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Arthrobacter|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 527
Score = 118 bits (285), Expect = 1e-25
Identities = 69/208 (33%), Positives = 115/208 (55%), Gaps = 7/208 (3%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 217
++ F ++D S M F K+ L IK+ + KA A P VNA ++
Sbjct: 320 VSIFVDVDASRTMEFVKR-LKVSRDFEGIKVSPLLILAKAVIWAAARNPSVNATWVDSAD 378
Query: 218 -----EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIE 382
EI + ++++ +A ATP+GL+VP I+N Q+++ ++ L + LA AR GK
Sbjct: 379 GSDTAEIHVKHFMNLGIAAATPRGLMVPNIKNAQDLSLKELALALNDLATTARAGKTRPA 438
Query: 383 EMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTY 562
EM GGT T++N G G GTPIINP + AI+ I ++P L+G+V+ R + + ++
Sbjct: 439 EMQGGTLTVTNIGALGIDTGTPIINPGEVAIVAFGTIKQKPWVLDGEVIPRWITTLGGSF 498
Query: 563 DHRLIDGREAVLFLRKIKEGVEDPATIV 646
DHR++DG + F+ + +E+PA ++
Sbjct: 499 DHRVVDGDLSARFMADVAAILEEPALLL 526
>UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=31; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Zymomonas mobilis
Length = 440
Score = 118 bits (285), Expect = 1e-25
Identities = 66/216 (30%), Positives = 115/216 (53%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++ + ++ M ++ R + L+ +IK+ + +KA A AL
Sbjct: 225 IARRLTESKQNIPHIYLTVDVQMDALLKLRSE-LNESLAVQNIKISVNDMLIKAQALALK 283
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN + ++++ DISVAV+ GL+ P+++ + + + + + L +AR
Sbjct: 284 ATPNVNVAFDGDQMLQFSQADISVAVSVEGGLITPILKQADTKSLSALSVEMKELIARAR 343
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G+L +E GGT +ISN G+FG +INPPQ++IL + RP ++ + I +
Sbjct: 344 EGRLQPQEYQGGTSSISNMGMFGIKQFNAVINPPQASILAIGSGERRPWVIDDAITIATV 403
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVA 649
I ++DHR+IDG +A F+ K VE P I+A
Sbjct: 404 ATITGSFDHRVIDGADAAAFMSAFKHLVEKPLGILA 439
>UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
sp. NRRL B-14911|Rep: Pyruvate dehydrogenase E2 -
Bacillus sp. NRRL B-14911
Length = 391
Score = 118 bits (284), Expect = 1e-25
Identities = 71/207 (34%), Positives = 118/207 (57%), Gaps = 4/207 (1%)
Frame = +2
Query: 47 TTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEII 226
T F ++D++ + FR++ KK ++ + + ++KA + AL PV N+ ++E +
Sbjct: 189 THFEDVDVTELSVFREE-----LKKQEKQVTMTAFYIKALSMALKRFPVFNSRLDEKAGL 243
Query: 227 YRDYVD--ISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGT 400
+ I VAV GL+VPVI N + T A+I + L KA G+L +E GGT
Sbjct: 244 IHLLPEHHIGVAVNAEDGLIVPVIGNAEEKTIAEIAEDLQNLTRKALDGRLLAKETAGGT 303
Query: 401 FTISN-GGVFGSLMGTPIINPPQSAILGMHGIFERPIA-LNGQVVIRPMMYIALTYDHRL 574
FT+SN G + GS TPII PQ++I+ +H + P+ + Q+VIR +M +++++DHR+
Sbjct: 304 FTVSNVGPLNGSTGATPIILHPQTSIISLHKTKKMPVVDKDDQIVIRSIMKLSMSFDHRI 363
Query: 575 IDGREAVLFLRKIKEGVEDPATIVAGL 655
DG AV F + E +E+P ++ L
Sbjct: 364 ADGAAAVGFTNRFAELIENPKLMLLEL 390
>UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, long
form; n=1; Caulobacter sp. K31|Rep: Dihydrolipoamide
acetyltransferase, long form - Caulobacter sp. K31
Length = 415
Score = 118 bits (284), Expect = 1e-25
Identities = 75/215 (34%), Positives = 103/215 (47%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +A+ T + E+D + + L L +KAAA AL
Sbjct: 202 IARRLTEAKATIPHF--YLEVDCEIDELLKSRETLNARSDGQYNLSLNDLVIKAAALALR 259
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P N ++ II VDISVAVAT GL+ P++R A I + LA +AR
Sbjct: 260 QVPEANTAWTDDAIIQFQDVDISVAVATDGGLITPIVRQADRRGLASISAEVRTLAARAR 319
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G+L E GG+FTISN G+FG + IINPPQS IL + RP+ V +
Sbjct: 320 EGRLEPAEFQGGSFTISNLGMFGVRAFSAIINPPQSCILAVGAAERRPVVRGEACVPATV 379
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M L+ DHR +DG +L K +E P ++
Sbjct: 380 MTCTLSVDHRAVDGVVGARYLAAFKSLIEQPLRLM 414
>UniRef50_Q057U1 Cluster: Pyruvate dehydrogenase E2 component; n=1;
Buchnera aphidicola str. Cc (Cinara cedri)|Rep: Pyruvate
dehydrogenase E2 component - Buchnera aphidicola subsp.
Cinara cedri
Length = 417
Score = 118 bits (284), Expect = 1e-25
Identities = 67/200 (33%), Positives = 118/200 (59%), Gaps = 4/200 (2%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKH-LDTFTKKHSI-KLGLMSPFVKAAANALMDQPVVNAVIEEN 217
+T F+E D++ + FRK + L+ K S K+ L+S VK+ +AL+ P N++++++
Sbjct: 212 VTQFDEADITELEDFRKSYNLNQLNKNKSFQKVSLLSFLVKSVIHALLKYPRFNSILDKS 271
Query: 218 E--IIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 391
+ II + ++I +AV T GL+VPV+++++N T +I I + K + +L EM
Sbjct: 272 KKNIIIKKDINIGIAVDTHDGLLVPVLKSLKNKTIYEISNNIFNVVTKTKNNQLCTSEMT 331
Query: 392 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 571
G+FTIS+ G G + TPIIN P+ ILG+ +P+ + R ++ +++YDHR
Sbjct: 332 DGSFTISSLGGIGGIGFTPIINAPEVCILGISKADIKPVWNKKKFYPRLILPFSISYDHR 391
Query: 572 LIDGREAVLFLRKIKEGVED 631
+IDG + V F +K+ + D
Sbjct: 392 VIDGADGVRFTTFLKDILSD 411
>UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=2;
Alphaproteobacteria|Rep: Pyruvate dehydrogenase E2
component - Erythrobacter sp. NAP1
Length = 463
Score = 118 bits (284), Expect = 1e-25
Identities = 71/211 (33%), Positives = 109/211 (51%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++ T +I + ++ RK+ L+ + +KL + +KA A AL+
Sbjct: 249 IARRLTESKQTVPHYYLTMDIVLDPLLKLRKE-LNASLEPDGVKLSVNDLLIKALARALI 307
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P N + + DISVAVA P GL+ PVI A I + LA KAR
Sbjct: 308 RVPQCNVSYHGDTMRKYSRADISVAVAAPSGLITPVITEADTKGLAQISKEMKELAGKAR 367
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
GKL E GGT ++SN G+FG +INPPQ IL + + P ++G++ +
Sbjct: 368 DGKLQPHEYQGGTASLSNLGMFGIKQFDAVINPPQGMILAVGAGQQVPYVIDGEIKPATV 427
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
++ + ++DHR IDG E + IK+ VE+P
Sbjct: 428 LHASGSFDHRAIDGAEGAQLMEAIKQLVENP 458
>UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=7; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Pseudomonas
aeruginosa
Length = 547
Score = 118 bits (284), Expect = 1e-25
Identities = 71/203 (34%), Positives = 114/203 (56%), Gaps = 2/203 (0%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 217
+T F++ D++ + AFR +K +KL ++ +KA A+ L + P N+ + +
Sbjct: 345 VTQFDQSDITDMEAFRVAQ-KAAAEKAGVKLTVLPILLKACAHLLKELPDFNSSLAPSGK 403
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
+I + YV I AV TP GL+VPVIR+V + + A LA+KAR KL+ + M G
Sbjct: 404 ALIRKKYVHIGFAVDTPDGLLVPVIRDVDRKSLLQLAAEAADLADKARNKKLSADAMQGA 463
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
FTIS+ G G TPI+N P+ AILG+ +P+ R M+ ++L+YDHR+I
Sbjct: 464 CFTISSLGHIGGTGFTPIVNAPEVAILGVSKATMQPVWDGKAFQPRLMLPLSLSYDHRVI 523
Query: 578 DGREAVLFLRKIKEGVEDPATIV 646
+G A F +++ E + D T++
Sbjct: 524 NGAAAARFTKRLGELLADIRTLL 546
>UniRef50_A4SZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes precursor; n=1; Polynucleobacter
sp. QLW-P1DMWA-1|Rep: Catalytic domain of components of
various dehydrogenase complexes precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 472
Score = 118 bits (283), Expect = 2e-25
Identities = 71/196 (36%), Positives = 108/196 (55%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEI 223
+T ++ D++ + FR L+ KK ++K+ L++ +KAA AL P NA ++ E+
Sbjct: 272 VTYHDDADITDLEKFRSD-LNKEGKKDAVKITLLAFLIKAAVAALKKYPTFNASLDGEEL 330
Query: 224 IYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTF 403
I + Y I AV T GLVVPVIRN +I A LA+ AR GKL E+M G +F
Sbjct: 331 ILKKYCHIGFAVDTNIGLVVPVIRNADQKGILEIAKETAELAQLARDGKLKPEQMQGASF 390
Query: 404 TISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDG 583
TIS+ G G PIIN P+ AIL ++ +P+ + + R + +++T DHR+IDG
Sbjct: 391 TISSLGGIGGTYCAPIINAPEVAILAVNKSAIKPVWDGAEFIPRLICPLSMTADHRVIDG 450
Query: 584 REAVLFLRKIKEGVED 631
A F + + + D
Sbjct: 451 ALATHFTTYLAQLLAD 466
>UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=2; Leishmania|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Leishmania major
Length = 477
Score = 118 bits (283), Expect = 2e-25
Identities = 70/208 (33%), Positives = 117/208 (56%), Gaps = 6/208 (2%)
Frame = +2
Query: 50 TFNE-IDMSHIMAFRKKHLDTFTK--KHSIKLGLMSPFVKAAANALMDQPVVNA--VIEE 214
TF+E +++ +M R D + K KL M F+KAA+ AL P +NA ++
Sbjct: 269 TFSEECELTRLMEVRGSLKDVVKERSKGKAKLSFMPFFLKAASIALQHHPDINAHCPVDC 328
Query: 215 NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 394
+ ++ + +I A+ TP GL+VPV+++V+ + DI + L E+ ++ KLT ++M G
Sbjct: 329 SALVRKAAHNIGFAMDTPNGLIVPVVKHVERKSILDIANDMQVLIERGKSNKLTTQDMTG 388
Query: 395 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHR 571
GTFT+SN GV G+ + TP++ PPQ AI + + + P NG + ++ ++ T DHR
Sbjct: 389 GTFTLSNIGVIGATVTTPVLLPPQVAIGAIGRLQKLPRFDANGSLYAANLICVSFTADHR 448
Query: 572 LIDGREAVLFLRKIKEGVEDPATIVAGL 655
+IDG V F K+ +E P ++ L
Sbjct: 449 VIDGASMVRFANTYKQLLEHPENMLVDL 476
>UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=47; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Azotobacter vinelandii
Length = 638
Score = 118 bits (283), Expect = 2e-25
Identities = 72/203 (35%), Positives = 110/203 (54%), Gaps = 2/203 (0%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 217
+T F D++ + AFR +K +KL ++ +KA A L + P N+ + +
Sbjct: 436 VTQFESADITELEAFRVAQ-KAVAEKAGVKLTVLPLLLKACAYLLKELPDFNSSLAPSGQ 494
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
+I + YV I AV TP GL+VPVIRNV + + A LAEKAR+ KL + M G
Sbjct: 495 ALIRKKYVHIGFAVDTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGA 554
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
FTIS+ G G TPI+N P+ AILG+ +P+ R M+ ++L+YDHR+I
Sbjct: 555 CFTISSLGHIGGTAFTPIVNAPEVAILGVSKASMQPVWDGKAFQPRLMLPLSLSYDHRVI 614
Query: 578 DGREAVLFLRKIKEGVEDPATIV 646
+G A F +++ + + D I+
Sbjct: 615 NGAAAARFTKRLGDLLADIRAIL 637
>UniRef50_Q1GTH9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Alphaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 441
Score = 117 bits (282), Expect = 3e-25
Identities = 69/222 (31%), Positives = 118/222 (53%), Gaps = 6/222 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAM---LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPF-VKAAA 169
I R + A+N A + F ++ + A + D + S M PF + A
Sbjct: 219 IGMRRRIAENMAASKRAIPHFTYVEEMDVTALEEMRADLNANRGSRPKLTMLPFLIVAIC 278
Query: 170 NALMDQPVVNAVIEENEIIYRDY--VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAG 343
+ + P++NA ++ + Y V + +A T GL+VPVIR+ Q+ + I
Sbjct: 279 RTIPEFPMINARYDDEAGVVTRYGAVHLGMATQTDAGLMVPVIRDAQDKNVWQLASEITR 338
Query: 344 LAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQ 523
LAE ARTGK+ +EE+ GGT T+++ G G + TP+IN P+ AI+G + I ERPI
Sbjct: 339 LAEAARTGKVKVEELTGGTLTVTSLGPLGGIATTPVINRPEVAIIGPNKIVERPIFDGDD 398
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVA 649
+ +M ++++ DHR++DG +A +++ +K+ +E P + A
Sbjct: 399 IRRAKLMNLSISCDHRVVDGWDAASYVQALKKLIETPVLLFA 440
>UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=46; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Homo sapiens (Human)
Length = 614
Score = 117 bits (282), Expect = 3e-25
Identities = 72/217 (33%), Positives = 116/217 (53%), Gaps = 2/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQRL ++ T +++M ++ RK+ L+ + S K+ + +KA+A A +
Sbjct: 399 IAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKE-LNKILEGRS-KISVNDFIIKASALACL 456
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P N+ + I VD+SVAV+TP GL+ P++ N I + LA KAR
Sbjct: 457 KVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAR 516
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQ--VVIR 535
GKL E GGTFTISN G+FG + IINPPQ+ IL + ++ + + + +
Sbjct: 517 EGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVA 576
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
MM + L+ DHR++DG +L + ++ +E P T++
Sbjct: 577 SMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITML 613
>UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 399
Score = 117 bits (281), Expect = 3e-25
Identities = 65/215 (30%), Positives = 112/215 (52%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+ R+ + A T E+D+S ++ R + K+ + KA A++
Sbjct: 188 VGSRMLQSLRETAQYTLGREVDISALIKVRME-----LKQKGSPANITDLIHKAVVQAIL 242
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+ PV+ AVI+ ++++ V + AVA L+VPVI+N + ++ + L +
Sbjct: 243 ENPVMQAVIDGDDMVVPAEVHLGFAVARGDELLVPVIKNAHRLNLNEMAVERRRLTDAVL 302
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G + EE+ GGTFT++N G +G TP++ P QSAILG+ I ERP+ NG +
Sbjct: 303 QGIIKPEELQGGTFTVTNLGTYGVDFFTPVLYPKQSAILGIGRIVERPVLENGNIRSAQF 362
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M ++LT DH++I+G A FL ++ E + P ++
Sbjct: 363 MTLSLTVDHQVINGAPAARFLNRLAELLSQPEVLL 397
>UniRef50_A1SQ65 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Nocardioides sp.
JS614|Rep: Catalytic domain of components of various
dehydrogenase complexes - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 427
Score = 117 bits (281), Expect = 3e-25
Identities = 64/173 (36%), Positives = 101/173 (58%)
Frame = +2
Query: 131 KLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNM 310
++ L VKA A A P +N V + + VD++VAVAT +GLV PV+R+V ++
Sbjct: 255 RVSLNDLVVKAVAAAHARVPEMNVVWTPDAVRSFSSVDVAVAVATDRGLVTPVLRDVTSL 314
Query: 311 TYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHG 490
T + + LA +AR G+L +E++GGT +++N G++G IINPP +AIL +
Sbjct: 315 TVTAVAAKVQDLAARAREGRLKQDELEGGTISVTNLGMYGVEEFAAIINPPHAAILAVGA 374
Query: 491 IFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVA 649
+ E P+ +G VV ++ + L+ DHR +DG A +L + VE PA I+A
Sbjct: 375 VREEPVVEDGAVVPGKVLTVTLSVDHRPVDGVVAARWLAAFVDLVEHPARILA 427
>UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=3; Trypanosoma|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Trypanosoma brucei
Length = 439
Score = 117 bits (281), Expect = 3e-25
Identities = 70/210 (33%), Positives = 115/210 (54%), Gaps = 8/210 (3%)
Frame = +2
Query: 47 TTFNEIDMSHIMAFRKKHLDTFTK-----KHSIKLGLMSPFVKAAANALMDQPVVNAVI- 208
T +E+++S ++ F+ D + K+ LM F+KAA+ +L+ P +NA +
Sbjct: 227 TACDEVEVSQLLNFQHILRDALNSSSEGVRDGSKVSLMPLFIKAASQSLLQYPELNAHVS 286
Query: 209 -EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEE 385
E +++ + I A+ TPKGLVVPV+R+VQ + A++ + L R ++ +
Sbjct: 287 SECDKLFVKKAHHIGFAMDTPKGLVVPVVRDVQQKSVAELVHEVNELVTLGRKSQIPPDR 346
Query: 386 MDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTY 562
M GTFT+SN G G++ TP++NPPQ AI + I + P +G VV ++ ++ T
Sbjct: 347 MKDGTFTLSNIGPIGAIYATPMLNPPQVAIGAIGRIQQLPRFDASGNVVRANILAMSWTA 406
Query: 563 DHRLIDGREAVLFLRKIKEGVEDPATIVAG 652
DHR+IDG V F K +E P ++AG
Sbjct: 407 DHRVIDGATLVRFSNAFKRCLESPGLLIAG 436
>UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=103;
Proteobacteria|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Shewanella oneidensis
Length = 677
Score = 116 bits (280), Expect = 4e-25
Identities = 71/204 (34%), Positives = 110/204 (53%), Gaps = 3/204 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHS-IKLGLMSPFVKAAANALMDQPVVNAVIEEN- 217
+T F+E D++ + FRK+ D KK + K+ + +KA A L PV N+ + +
Sbjct: 473 VTQFDEADITEMEEFRKQQNDAAAKKKADYKITPLVFMMKAVAKTLQQFPVFNSSLSSDG 532
Query: 218 -EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDG 394
+I + Y I VAV TP GLVVPV+R+V ++ +A ++ +AR GKL +M G
Sbjct: 533 ESLIQKKYFHIGVAVDTPNGLVVPVVRDVDKKGIIELSRELADISIRARDGKLKSADMQG 592
Query: 395 GTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRL 574
FTIS+ G G TPI+N P AILG+ +P + + M+ ++L+YDHR+
Sbjct: 593 SCFTISSLGGIGGTAFTPIVNYPDVAILGVSKSEIKPKWNGKEFEPKLMLPLSLSYDHRV 652
Query: 575 IDGREAVLFLRKIKEGVEDPATIV 646
IDG A F + + D T++
Sbjct: 653 IDGAMAARFSVTLSGILSDIRTLI 676
>UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Psychrobacter|Rep: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex -
Psychrobacter arcticum
Length = 578
Score = 116 bits (280), Expect = 4e-25
Identities = 72/212 (33%), Positives = 112/212 (52%), Gaps = 6/212 (2%)
Frame = +2
Query: 29 NTNAMLTTFNEIDMSHIMAFR--KKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNA 202
N N L + D+S I + L K I L +++ VKA A AL P N+
Sbjct: 366 NYNTYLPQVTQFDLSDITETEQLRSELKGGMKAEGIGLTILAFIVKATAYALTQHPRFNS 425
Query: 203 VIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLT 376
+ ++ ++I R V++ +AVAT GL+VPVI+N I + I LA KAR KL+
Sbjct: 426 HLSDDNTQVILRKSVNMGIAVATDDGLIVPVIKNAHEKGIKQIAIEIGELAIKARDKKLS 485
Query: 377 IEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRP--MMYI 550
+++ G +FTIS+ G+ G TP++N PQ ILG +P + P M+ +
Sbjct: 486 TKDLQGASFTISSQGILGGTAFTPLVNWPQVGILGASEATMQPKWNAAKQAFEPRLMLPL 545
Query: 551 ALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+L+YDHR+I+G +A +F R + + DP I+
Sbjct: 546 SLSYDHRVINGADAAVFTRYVATLLADPRRIL 577
>UniRef50_A4XHV3 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Caldicellulosiruptor
saccharolyticus DSM 8903|Rep: Catalytic domain of
components of various dehydrogenase complexes -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 460
Score = 116 bits (280), Expect = 4e-25
Identities = 68/216 (31%), Positives = 113/216 (52%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + + T A LT D S+I+ FRK+ + K + + + A + L
Sbjct: 244 IAKAMYLSLTTTAQLTLHTSFDASNILEFRKRVKENREKLGLEDITINDIILFAVSRVLP 303
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+NA ++++ Y V + AV T +GL+VP I N + I L + R
Sbjct: 304 KHKALNAHFLDDKMRYFKNVHLGFAVDTERGLMVPTIFNSNKKSLNQISKEAKELIQLCR 363
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G + + + G TFT++N G FG TP++NPPQ+ ILG++ I R NGQ+ P
Sbjct: 364 KGTINPDLLKGATFTVTNLGSFGIEGFTPVLNPPQTGILGVNTIVMRAKEQNGQITYYPA 423
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVA 649
+ ++LT+DHR +DG +A FL+ +K+ +E+ ++A
Sbjct: 424 IGLSLTFDHRALDGADAARFLQDLKKWLENFELLLA 459
>UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Schizosaccharomyces pombe (Fission yeast)
Length = 483
Score = 116 bits (280), Expect = 4e-25
Identities = 78/218 (35%), Positives = 109/218 (50%), Gaps = 3/218 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RL +++N N ++M I+ R L+ KL + +KA AL
Sbjct: 267 IASRLAESKNMNPHYYVTVSVNMEKIIRLRAA-LNAMADGR-YKLSVNDLVIKATTAALR 324
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VNA + I VDIS+AVATP GL+ PVIRN + A+I ++AR
Sbjct: 325 QVPEVNAAWMGDFIRQYKNVDISMAVATPSGLITPVIRNTHALGLAEISTLAKDYGQRAR 384
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPI---ALNGQVVI 532
KL EE GGTFTISN G+F T IINPPQ+ IL + + + +
Sbjct: 385 NNKLKPEEYQGGTFTISNLGMFPVDQFTAIINPPQACILAVGTTVDTVVPDSTSEKGFKV 444
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
P+M L+ DHR++DG A F +K+ +E+P I+
Sbjct: 445 APIMKCTLSSDHRVVDGAMAARFTTALKKILENPLEIM 482
>UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 484
Score = 116 bits (279), Expect = 6e-25
Identities = 76/223 (34%), Positives = 117/223 (52%), Gaps = 8/223 (3%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKK-HLDTFTKKHSIKLGLMSPFVKAAANAL 178
I RL ++ T ++I ++ ++ R+ + D K + KL + VKA + A+
Sbjct: 262 IGSRLLESTQTIPSYIVSSDISVTKLLRLRQSLNNDPANKNNDYKLSINDILVKAISLAV 321
Query: 179 MDQPVVNAVIEENEIIYRDY--VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAE 352
P VN E E + R + VD+SVAVATP GL+ P+++NV + I + L +
Sbjct: 322 KRVPEVNTCWLEKENVIRQFENVDVSVAVATPTGLITPIVKNVNSKGLVSISNEVKDLVK 381
Query: 353 KARTGKLTIEEMDGGTFTISNGGVFGSL-MGTPIINPPQSAILGMHGIFERPI----ALN 517
+AR KL EE GGT ISN G+ ++ M T IINPPQSAIL + P+ + N
Sbjct: 382 RARINKLNPEEFQGGTICISNLGMNNAVSMFTSIINPPQSAILAVGTTKRIPVEDVTSKN 441
Query: 518 GQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
G ++ I T+DHR IDG + F+ +K +E+P ++
Sbjct: 442 G-FTFNDVITITGTFDHRTIDGAKGGEFMHALKTIIENPLQLL 483
>UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=2; Mycoplasma|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
pneumoniae
Length = 402
Score = 116 bits (279), Expect = 6e-25
Identities = 63/208 (30%), Positives = 111/208 (53%), Gaps = 2/208 (0%)
Frame = +2
Query: 14 LKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPV 193
+K +N A + TF ++ + + +R+ K+++K+ + FVKA NAL PV
Sbjct: 189 VKSHENIPATILTFY-VNATKLKQYRESVNGLALSKYNMKISFFAFFVKAIVNALKKFPV 247
Query: 194 VNAVI--EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTG 367
N E N I+ V++ +AV TP GL+VP I+ Q + DI I LA +AR+
Sbjct: 248 FNGRYDKERNLIVLNKDVNVGIAVDTPDGLIVPNIKQAQTKSVVDIAKDIVDLANRARSK 307
Query: 368 KLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMY 547
++ + ++ GT +++N G G+ GTPII P+ I+ + ER + G V + ++
Sbjct: 308 QIKLPDLSKGTISVTNFGSLGAAFGTPIIKHPEMCIVATGNMEERVVRAEGGVAVHTILP 367
Query: 548 IALTYDHRLIDGREAVLFLRKIKEGVED 631
+ + DHR +DG + F ++I + +E+
Sbjct: 368 LTIAADHRWVDGADVGRFGKEIAKQIEE 395
>UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E2
component of the pyruvate dehydrogenase complex; n=2;
Moraxellaceae|Rep: Dihydrolipoamide S-acetyltransferase,
E2 component of the pyruvate dehydrogenase complex -
Acinetobacter sp. (strain ADP1)
Length = 661
Score = 116 bits (278), Expect = 8e-25
Identities = 65/198 (32%), Positives = 111/198 (56%), Gaps = 2/198 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 217
+T F+ D++ + A+R F KK I L +M+ +KA A+ L ++ + ++
Sbjct: 459 VTQFDLADITELEAWRNDLKGNF-KKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGK 517
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
++ R + + +AVATP GL VPV+RN T I + + + +KAR KL+ +++ G
Sbjct: 518 SVLLRKEIHMGIAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGA 577
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
FTIS+ G G TP++N PQ AILG+ +P+ R M+ ++L+YDHR+I
Sbjct: 578 NFTISSLGAIGGTAFTPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVI 637
Query: 578 DGREAVLFLRKIKEGVED 631
+G +A F K+ + ++D
Sbjct: 638 NGADAARFTNKLTKLLQD 655
>UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate
dehydrogenase complex, component X; n=4;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyruvate dehydrogenase complex, component X -
Strongylocentrotus purpuratus
Length = 482
Score = 115 bits (277), Expect = 1e-24
Identities = 69/211 (32%), Positives = 111/211 (52%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++ T + + +++ I+ RK+ KK +IK+ + +KAAA AL
Sbjct: 274 IAKRLTESKTTIPHYYSMVDCELTEIVRLRKQ-----LKKDNIKVSVNDFIIKAAAMALK 328
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN +DISVAVAT GL+ P+++ +I + LA +AR
Sbjct: 329 QVPEVNVTWNGQSATPLSSIDISVAVATDGGLITPIVKGADAKGLMEISANVRDLATRAR 388
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KL ++E GG+F+ISN G+FG + +INPPQS I+ + G +A+
Sbjct: 389 ANKLKLDEFQGGSFSISNLGMFGISEFSAVINPPQSCIMAIGG---SQLAIGKDRKPLTY 445
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
M + ++ D R++DG A FL+ K+ +E P
Sbjct: 446 MTVTMSSDARVVDGALASRFLKTFKQNIESP 476
>UniRef50_A0JZU9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Micrococcineae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 518
Score = 115 bits (277), Expect = 1e-24
Identities = 55/149 (36%), Positives = 89/149 (59%)
Frame = +2
Query: 209 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 388
E EI+ D +++ A T +GL+VP +RN M+ +++ I L R GK T E+
Sbjct: 370 ESQEIVAFDGINLGFAAQTDRGLMVPSVRNAGKMSARELDAEIRRLTAVVREGKATPSEL 429
Query: 389 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 568
GTFT++N GVFG IIN P+ ILG+ I ++P +NG++ +R + + LT+DH
Sbjct: 430 GSGTFTLNNYGVFGVDGSAAIINHPEVGILGVGRIIDKPWVVNGELAVRKVTELTLTFDH 489
Query: 569 RLIDGREAVLFLRKIKEGVEDPATIVAGL 655
R+ DG A FLR + + +E+P +++A +
Sbjct: 490 RVCDGGTAGGFLRYVADAIENPGSVLADM 518
>UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=4; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Roseiflexus sp. RS-1
Length = 459
Score = 115 bits (276), Expect = 1e-24
Identities = 70/200 (35%), Positives = 107/200 (53%), Gaps = 2/200 (1%)
Frame = +2
Query: 59 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY 238
E+DM +A R + ++ I + M VKA A AL+ P +NA ++ II
Sbjct: 262 EVDMGAALALRAQANAGRPREDQISVNDM--VVKACAVALLAFPNLNASYSDDGIILHPT 319
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
V+I++AVA GL+ PV+ N Q+ + I + AR GK+T + + GGTFT+SN
Sbjct: 320 VNIAIAVALESGLMAPVVANCQDRSLGSIARETKRIVALAREGKITPDLLQGGTFTVSNL 379
Query: 419 GVFGSLMGTPIINPPQSAILGMHGIFERPIAL--NGQVVIRPMMYIALTYDHRLIDGREA 592
G++G T II PPQ+A L + I P + +VV + +M + L+ DHR+ DG E
Sbjct: 380 GMYGIPEFTSIITPPQAASLAVGAIRRTPAFKDDSDEVVAKHLMMLTLSADHRVTDGAEV 439
Query: 593 VLFLRKIKEGVEDPATIVAG 652
FL +K +E P ++ G
Sbjct: 440 ARFLNDVKRLLEQPLALLVG 459
>UniRef50_Q1V1J3 Cluster: Dihydrolipoamide S-acetyltransferase; n=3;
Bacteria|Rep: Dihydrolipoamide S-acetyltransferase -
Candidatus Pelagibacter ubique HTCC1002
Length = 434
Score = 114 bits (275), Expect = 2e-24
Identities = 68/207 (32%), Positives = 114/207 (55%), Gaps = 3/207 (1%)
Frame = +2
Query: 14 LKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPV 193
L ++ T +T +E D++ + FR D +T + K+ ++ +KA +L P
Sbjct: 219 LVNSWTTIPHVTNHDEADITEMEVFRTSLTDMYTGERK-KITPLAFIIKALVASLKKFPS 277
Query: 194 VNAVI---EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKART 364
N+ I E +I + Y + +AV TP GL+VP IR+ N + + I + ++++ R
Sbjct: 278 FNSSIDNIENGKITIKKYFHVGIAVDTPHGLMVPKIRSADNKSISYISNELKTVSDQCRN 337
Query: 365 GKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMM 544
K+ +E GG+ TI++ G G TPIIN P+ AILG+ ++ I +NG+ R M+
Sbjct: 338 LKIDKKEFFGGSMTITSLGGIGGSFFTPIINYPEVAILGVGKAQKKQIFINGKFETRTML 397
Query: 545 YIALTYDHRLIDGREAVLFLRKIKEGV 625
++L+YDHR+IDG EA F +KE +
Sbjct: 398 PLSLSYDHRIIDGAEAARFNNDLKENL 424
>UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2;
Cystobacterineae|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Stigmatella
aurantiaca DW4/3-1
Length = 533
Score = 114 bits (275), Expect = 2e-24
Identities = 64/215 (29%), Positives = 112/215 (52%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IAQR+ + + +++M M R++ K K+ + VKA A AL
Sbjct: 323 IAQRMSEVKPGVPHFYLTVDVEMDAAMKIREE-----AKALESKVSVNDIVVKAVAVALR 377
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +N ++ N I+ D+ +AVA GL+ P+I++ I LAE+AR
Sbjct: 378 RSPKMNVSLQGNTILQFATADVGIAVAIEDGLITPIIKDADQKGLQAISTEARELAERAR 437
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
L +E GG+ T+SN G++G +INPPQ+AI+ + + ++ + +GQ+ +R +
Sbjct: 438 KKALKPDEYTGGSITVSNLGMYGIDQFVAVINPPQAAIIAVGAVADKAVVRDGQITVRKI 497
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ + L+ DHR+IDG +LR++K +E P ++
Sbjct: 498 LTVTLSGDHRVIDGATGAEYLRELKNLLEHPMRLL 532
>UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ...; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ... - Tribolium
castaneum
Length = 429
Score = 114 bits (274), Expect = 2e-24
Identities = 70/204 (34%), Positives = 111/204 (54%), Gaps = 4/204 (1%)
Frame = +2
Query: 56 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIY 229
+EI ++ + R+ L + +KL M F+KAA+NAL PV+NA ++EN + Y
Sbjct: 228 DEIAVTQLSQLRQT-LKKLPETQDLKLSFMPFFIKAASNALQRFPVLNASLDENCENVTY 286
Query: 230 RDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTI 409
+ +I VA+ T GL VPVI+NV+ ++ +I + L + R+G + +++ GGTFTI
Sbjct: 287 KSEHNIGVAMDTKVGLAVPVIKNVETLSIIEISNELNRLIKSGRSGSFSPQDLAGGTFTI 346
Query: 410 SNGGVFGSLMGTPIINPPQSAI--LGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDG 583
SN G G P+I PP AI LG + R G VV ++ ++ DHR+IDG
Sbjct: 347 SNIGAIGGTYMKPVIMPPHVAIVALGASQVVPR-FDDAGNVVPVEVLNLSGAADHRIIDG 405
Query: 584 REAVLFLRKIKEGVEDPATIVAGL 655
F++ +K +E+P + L
Sbjct: 406 ATMARFVQTLKRQIENPYLLFLNL 429
>UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes; n=1; Psychromonas
ingrahamii 37|Rep: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes - Psychromonas
ingrahamii (strain 37)
Length = 431
Score = 114 bits (274), Expect = 2e-24
Identities = 69/212 (32%), Positives = 110/212 (51%), Gaps = 1/212 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKH-SIKLGLMSPFVKAAANAL 178
IA RL +++ T + ++ ++ R + + F K H ++KL + +KA A A+
Sbjct: 212 IASRLTESKTTIPHFYVSIDCEVDNLNLLRAE-FNAFYKDHENVKLTVNDFIIKAVALAI 270
Query: 179 MDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P +N++ + +DISVAV+T GL+ P++ N + + L K
Sbjct: 271 HKHPEINSMWLSEGVKKNKNIDISVAVSTDDGLMTPIVFNADRKGLITLSQNMKSLVSKT 330
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRP 538
R+GKL E GG FTISN G++ IINPPQS IL + + P+ + Q++I
Sbjct: 331 RSGKLQPNEYQGGGFTISNLGMYDIDSFNAIINPPQSCILAVGRAKKIPVVKDDQILIAN 390
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+M L+ DHR+IDG A FL+ K +E+P
Sbjct: 391 VMNCTLSVDHRVIDGSVAAEFLQTFKFYIENP 422
>UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 421
Score = 114 bits (274), Expect = 2e-24
Identities = 73/219 (33%), Positives = 119/219 (54%), Gaps = 5/219 (2%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRK---KHLDTFTKKHSIKLGLMSPFVKAAANA 175
A+RL +++ ++ + ++M R+ K L K+ + VKA+A A
Sbjct: 203 AERLTESKQQLPHFYLTVDVRLDNMMGIRETLNKQLADDKAAEGAKISVNDFIVKASAKA 262
Query: 176 LMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
L+ P VNA ++I DISVAV T +GL+VP++R+ + I + LA +
Sbjct: 263 LLAVPDVNASWLGDKIRKYKKADISVAVQTERGLMVPIVRSACCLGLKSISAEVKSLAGR 322
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR+G LT ++M GGTFTISN G+FG I+NPPQ+AIL + G + + N +
Sbjct: 323 ARSGSLTPQDMTGGTFTISNLGMFGVKNFAAIVNPPQAAILAVGGA-RKEVVKNAEGGYE 381
Query: 536 PMMYIA--LTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
++ ++ L+ DHR++DG +L+ K +EDP T++
Sbjct: 382 EVLVMSATLSCDHRVVDGAVGAQWLQSFKCYLEDPMTML 420
>UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases
acyltransferase; n=2; Bacteria|Rep: Probable 2-oxo acid
dehydrogenases acyltransferase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 416
Score = 113 bits (273), Expect = 3e-24
Identities = 69/194 (35%), Positives = 104/194 (53%), Gaps = 2/194 (1%)
Frame = +2
Query: 59 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY 238
E ++S ++A R++ + + +L L + A A AL P N + ++ I+
Sbjct: 215 EAEVSALLALRQR---LNAQADAPRLTLNHFVIAAVARALAAMPHQNRIWNDDHIVQFQG 271
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
+D+ VAV+T +GL+ PV+ + + + DI L + R GK T E+M GG +ISN
Sbjct: 272 IDVGVAVSTERGLMAPVLHGLDHASLDDIAAQSGALLGRVRAGKATREDMSGGAISISNA 331
Query: 419 GVFGSLMGTPIINPPQSAILGMHGIFE--RPIALNGQVVIRPMMYIALTYDHRLIDGREA 592
G+F PIINPPQSAILG+ I E RP G +R M + L DHRL DG A
Sbjct: 332 GMFNVTYMAPIINPPQSAILGVGSIRELFRPDE-QGAPALRREMGLVLAADHRLHDGASA 390
Query: 593 VLFLRKIKEGVEDP 634
+ FL + + ++DP
Sbjct: 391 LAFLNHVIDLLQDP 404
>UniRef50_Q4L1A5 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Mycoplasma synoviae|Rep: Dihydrolipoamide
acetyltransferase - Mycoplasma synoviae
Length = 309
Score = 113 bits (273), Expect = 3e-24
Identities = 62/213 (29%), Positives = 112/213 (52%), Gaps = 2/213 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ + ++ + A + ++M+ + R D+ K +K+ + +KA + AL
Sbjct: 91 IAKAMTNSWSNVAYTNLVHRVNMTKLWDLRSSIKDSLLKSEDVKITFLPFILKAVSVALK 150
Query: 182 DQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
+ P+ +A E + + + +++ AV T GL+VPVI+N ++ D+ ++ LA
Sbjct: 151 EFPLFSAKYNEAKSTLDFPGVINLGFAVDTEAGLMVPVIKNANALSVLDLAREVSRLASA 210
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
AR + ++M FT++N G GSL G P+IN P+ AILG+ I + G +V
Sbjct: 211 ARNKTIKPDDMKNAGFTVTNYGSVGSLWGVPVINYPELAILGVGAIQDEAFVEKGTLVAG 270
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+MY+ + DHR IDG + F ++K+ +E P
Sbjct: 271 KVMYLTVAADHRWIDGADVGRFASRVKQLLESP 303
>UniRef50_O45279 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 337
Score = 113 bits (273), Expect = 3e-24
Identities = 75/198 (37%), Positives = 106/198 (53%), Gaps = 1/198 (0%)
Frame = +2
Query: 59 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY 238
++ + I+A R+K KK + L +KAAA AL P VN V E I
Sbjct: 131 DVRIDDILALRQK-----LKKSGTAVSLNDFIIKAAALALRSVPTVN-VRWTPEGIGLGS 184
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
VDISVAVATP GL+ P++ N + I + L+ AR KL ++ GG+FTISN
Sbjct: 185 VDISVAVATPTGLITPIVENSDILGVLAISSKVKELSGLARESKLKPQQFQGGSFTISNL 244
Query: 419 GVFGSLMG-TPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAV 595
G+FGS+ T IINPPQ AIL + G ++++GQ+ + +M + L +D R I A
Sbjct: 245 GMFGSVTNFTAIINPPQCAILTIGGTRSEVVSVDGQLETQKLMGVNLCFDGRAISEECAK 304
Query: 596 LFLRKIKEGVEDPATIVA 649
FL E + DP ++A
Sbjct: 305 RFLLHFSESLSDPELLIA 322
>UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=6;
Anaplasmataceae|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Ehrlichia chaffeensis (strain Arkansas)
Length = 416
Score = 113 bits (272), Expect = 4e-24
Identities = 62/181 (34%), Positives = 98/181 (54%)
Frame = +2
Query: 92 KKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPK 271
K L+ + K+ + +KA A ++ P +N +++I+ +DISVAV+
Sbjct: 231 KLRLEINAENPDTKVTVNDFIIKAVAMSIKKFPEINVSWSDDKIVVFPSIDISVAVSIDN 290
Query: 272 GLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPI 451
GL+ P+I + +I + LA KA++GKL EE GG FT+SN G+FG I
Sbjct: 291 GLITPIIFGADKKSLLEISREVKALASKAKSGKLKPEEFQGGGFTVSNLGMFGIKEFYAI 350
Query: 452 INPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVED 631
+NPPQS I+ + +R + +N Q+ I ++ + L+ DHR+IDG A FL K +E
Sbjct: 351 VNPPQSCIMSVGCSEKRAMVVNEQICISNVVTVTLSVDHRVIDGVLAAKFLNCFKSYLEK 410
Query: 632 P 634
P
Sbjct: 411 P 411
>UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2
component, dihydrolipoamide acetyltransferase, putative;
n=13; Mycobacterium|Rep: 2-oxoisovalerate dehydrogenase
E2 component, dihydrolipoamide acetyltransferase,
putative - Mycobacterium tuberculosis
Length = 393
Score = 113 bits (272), Expect = 4e-24
Identities = 53/139 (38%), Positives = 83/139 (59%)
Frame = +2
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
V + AT +GL+VPV+ + Q+ ++ +A L AR G LT E+ G TFT+SN
Sbjct: 255 VHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNF 314
Query: 419 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 598
G G G P+IN P++AILG+ I RP+ + G+VV RP M + +DHR++DG +
Sbjct: 315 GALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTCVFDHRVVDGAQVAQ 374
Query: 599 FLRKIKEGVEDPATIVAGL 655
F+ ++++ +E P T + L
Sbjct: 375 FMCELRDLIESPETALLDL 393
>UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme
complex, dihydrolipoamide acetyltransferase component;
n=16; Proteobacteria|Rep: Pyruvate dehydrogenase
multienzyme complex, dihydrolipoamide acetyltransferase
component - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 583
Score = 113 bits (271), Expect = 6e-24
Identities = 69/190 (36%), Positives = 104/190 (54%), Gaps = 4/190 (2%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIE---- 211
+T + D++ + AFR ++ +K KL +++ +KA+ AL P N ++
Sbjct: 379 VTYHEDADITDLEAFRVA-INKENEKSGKKLTMLAFIIKASVRALQQFPEFNTSLDASGG 437
Query: 212 ENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMD 391
E ++Y+ Y +I+ A TP GLVVPVI+N + +I LA+KAR GKL +M
Sbjct: 438 EMSLVYKKYFNIAFAADTPNGLVVPVIKNADRKSVFEIAAESGELAKKARDGKLGPADMS 497
Query: 392 GGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHR 571
G FTIS+ G G PI+N P+ AILG++ +PI Q V R + ++LT DHR
Sbjct: 498 GACFTISSLGGIGGTYFAPIVNAPEVAILGVNKSAMKPIWDGKQFVPRLTLPMSLTADHR 557
Query: 572 LIDGREAVLF 601
+IDG A F
Sbjct: 558 VIDGALATRF 567
>UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase
homoserine dehydrogenase; n=23; Alphaproteobacteria|Rep:
Dihydrolipoamide acetyltransferase homoserine
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 454
Score = 112 bits (270), Expect = 7e-24
Identities = 71/218 (32%), Positives = 111/218 (50%), Gaps = 7/218 (3%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTF----TKKHSI---KLGLMSPFVK 160
IA+RL +A++T + ++ ++A R + T+K + KL + +K
Sbjct: 232 IARRLVEAKSTIPHFYLTLDCELDALLALRTQINAAAPMKKTEKGDVPAYKLSVNDMVIK 291
Query: 161 AAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIA 340
A A AL P NA E ++ + D+ VAV+ P GL+ P+IR+ T + I +
Sbjct: 292 AMAMALKAVPDANASWTETAMVKHKHADVGVAVSIPGGLITPIIRHADEKTLSTISNEMK 351
Query: 341 GLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNG 520
LA +AR+ KL EE GGT +SN G+FG +INPP + IL + ER + NG
Sbjct: 352 DLASRARSRKLKPEEYQGGTTAVSNLGMFGIKDFAAVINPPHATILAVGAGEERAVVKNG 411
Query: 521 QVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
++ I +M + L+ DHR +DG L K +E+P
Sbjct: 412 EIKIATVMSVTLSTDHRAVDGALGAELLVAFKRLIENP 449
>UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1;
Bacillus clausii KSM-K16|Rep: Acetoin dehydrogenase E2
component - Bacillus clausii (strain KSM-K16)
Length = 410
Score = 112 bits (270), Expect = 7e-24
Identities = 71/219 (32%), Positives = 122/219 (55%), Gaps = 4/219 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+ ++ + + A LT + + ++AFR+ L T ++ H ++L L + A A L
Sbjct: 193 IARNMRASLHNTAQLTLHRKAHANALLAFRRL-LKTESESHQLQLKLSVTVLIARATILA 251
Query: 182 DQPV--VNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
Q V +N+ E ++ + V + +A + GLVVPVIRN +++ + I +A
Sbjct: 252 LQQVGAMNSRYENGQLKEFENVHLGIATSLDDGLVVPVIRNADHLSIGQLATKIEKIAAN 311
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL--NGQVV 529
AR+G+ +E+ G TFTI+N G TPI+NP ++ ILG+ G ++ +AL +GQV
Sbjct: 312 ARSGQSNPDELSGSTFTITNLGASSIEYFTPILNPAETGILGV-GSLQQELALSEDGQVE 370
Query: 530 IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M +LT+DH+++DG A FL + + VE+P ++
Sbjct: 371 PVQKMPFSLTFDHQIVDGVLAAQFLDAVVKYVENPHLLI 409
>UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2;
Actinomycetales|Rep: Pyruvate dehydrogenase E2 -
Arthrobacter aurescens (strain TC1)
Length = 493
Score = 112 bits (270), Expect = 7e-24
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 5/178 (2%)
Frame = +2
Query: 137 GLMSPFVKAAANALMDQPVVNAVIE-----ENEIIYRDYVDISVAVATPKGLVVPVIRNV 301
GL++ + L P +N E EI+ + +++ A T +GLVVP +RN
Sbjct: 316 GLLAFIARFVTAGLKKYPALNTRFETASDGSQEIVGFEGINLGFAAQTDRGLVVPSVRNA 375
Query: 302 QNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILG 481
++ +++ I L AR GK T E+ GTFT++N GVFG IIN P+ A+LG
Sbjct: 376 HELSARELDAEIRRLTAVARDGKATPTELGSGTFTLNNYGVFGVDGSAAIINYPEVAMLG 435
Query: 482 MHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
+ I ++P +NG++ +R + + L +DHR+ DG A FLR + + +E+P +A +
Sbjct: 436 VGRIIDKPWVVNGELAVRKVTELTLAFDHRVCDGETAAGFLRYVADAIENPGGALADM 493
>UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase; n=3;
Thermoplasma|Rep: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase - Thermoplasma
volcanium
Length = 400
Score = 112 bits (270), Expect = 7e-24
Identities = 60/159 (37%), Positives = 95/159 (59%), Gaps = 2/159 (1%)
Frame = +2
Query: 176 LMDQPVVNAVIEE--NEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLA 349
L P +NA+ +E + + Y +I +AV TP GL V V+++ + +I I A
Sbjct: 247 LKQYPYLNAIYDEANRRYLIKKYYNIGIAVDTPDGLNVFVVKDADRKSMYEITAEITDKA 306
Query: 350 EKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVV 529
E+AR +L I+E+ TFTI+N G G ++ TPIIN P+ AILG+H + + NG
Sbjct: 307 ERARNNQLKIDEVQDSTFTITNVGTIGGVLSTPIINYPEVAILGVHRVMDE----NG--- 359
Query: 530 IRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ +MY++L+ DHRLIDG A F+ +K+ +EDP +++
Sbjct: 360 -KKIMYLSLSCDHRLIDGAVATRFIMDLKKIIEDPNSLI 397
>UniRef50_P11182 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex,
mitochondrial precursor (EC 2.3.1.168)
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase); n=29; Eumetazoa|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex, mitochondrial
precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) - Homo sapiens (Human)
Length = 482
Score = 112 bits (270), Expect = 7e-24
Identities = 68/203 (33%), Positives = 111/203 (54%), Gaps = 3/203 (1%)
Frame = +2
Query: 56 NEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN--EIIY 229
+EID++ ++ R++ L IKL M F+KAA+ L+ P++NA ++EN I Y
Sbjct: 280 DEIDLTELVKLREE-LKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITY 338
Query: 230 RDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTI 409
+ +I +A+ T +GL+VP ++NVQ + DI + L + G+L+ ++ GGTFT+
Sbjct: 339 KASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTL 398
Query: 410 SNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGR 586
SN G G P+I PP+ AI + I P G+V +M ++ + DHR+IDG
Sbjct: 399 SNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 458
Query: 587 EAVLFLRKIKEGVEDPATIVAGL 655
F K +E+PA ++ L
Sbjct: 459 TMSRFSNLWKSYLENPAFMLLDL 481
>UniRef50_A6PJ30 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Shewanella sediminis
HAW-EB3|Rep: Catalytic domain of components of various
dehydrogenase complexes - Shewanella sediminis HAW-EB3
Length = 544
Score = 112 bits (269), Expect = 1e-23
Identities = 67/214 (31%), Positives = 120/214 (56%), Gaps = 3/214 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
+A+ + ++ +T T EID++ ++ R+ ++ +KL +M F+K+ + AL
Sbjct: 324 MAKMMTESVSTIPHFTYCEEIDLTELVTLRESMKKKYSTDE-LKLTMMPFFMKSMSLALK 382
Query: 182 DQPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
PV+N+ + E+ E+ Y +I +AV + GL+VP +++VQN + +I I L
Sbjct: 383 QFPVINSRVNEDCSELTYLSSHNIGMAVDSKVGLLVPNVKDVQNKSILEIAAEITRLTTA 442
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVI 532
AR+G+++ ++ GT +ISN G G + TPIIN P+ AI+ + + P +G+V
Sbjct: 443 ARSGRVSPNDLKSGTVSISNIGALGGTVATPIINKPEVAIVALGKLQVLPRFNADGEVEA 502
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
R +M I+ + DHR+IDG F K+ +E+P
Sbjct: 503 RKIMQISWSGDHRVIDGGTIARFCNLWKQYLEEP 536
>UniRef50_A1KCD0 Cluster: Putative uncharacterized protein; n=1;
Azoarcus sp. BH72|Rep: Putative uncharacterized protein
- Azoarcus sp. (strain BH72)
Length = 237
Score = 112 bits (269), Expect = 1e-23
Identities = 65/166 (39%), Positives = 92/166 (55%)
Frame = +2
Query: 131 KLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNM 310
KL + + + A A AL P +NA++ E E+ D ++I VAVA GL+VPVIR
Sbjct: 67 KLSVNAFVLHAVAQALRAHPRLNALMREKEVELVDDINIGVAVALDDGLMVPVIRQADTK 126
Query: 311 TYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHG 490
A + LAE AR G LT GTFT++N G +PIINPPQ AILG+
Sbjct: 127 PVAALAAETRQLAEGARAGALTGGAYQRGTFTVTNLGSTPVDRFSPIINPPQVAILGVGR 186
Query: 491 IFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
++ + +G +V P++ + L +DHR +DG A LFL +I +E
Sbjct: 187 TRQQAVVKDGAIVAAPVVNLTLVFDHRAVDGYPAALFLGEIARRLE 232
>UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1;
Dictyostelium discoideum AX4|Rep: Dihydrolipoyl
transacylase - Dictyostelium discoideum AX4
Length = 517
Score = 111 bits (268), Expect = 1e-23
Identities = 66/199 (33%), Positives = 114/199 (57%), Gaps = 3/199 (1%)
Frame = +2
Query: 59 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI--EENEIIYR 232
E M + R K + + IKL + +KAA+ +L+ PV+N+ I ++ EIIY+
Sbjct: 316 EYIMDSLSDLRNK-VKPLAAEKGIKLSYLPFIIKAASLSLLRYPVLNSSISQDQTEIIYK 374
Query: 233 DYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTIS 412
+Y +I +A+ +P+GL+VP I+NV++ + +I + L E + G LT +M GGTFT+S
Sbjct: 375 NYHNIGIAMDSPQGLLVPNIKNVESKSIFEIAKELNRLQELSGKGLLTPNDMSGGTFTLS 434
Query: 413 NGGVFGSLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGRE 589
N G G L +P++ P+ I + I P + V+ + +M I+ + DHR+IDG
Sbjct: 435 NIGTIGGLHSSPVLLLPEVCIGAIGKIQSLPRFNKHHAVITQSIMNISWSGDHRVIDGAT 494
Query: 590 AVLFLRKIKEGVEDPATIV 646
F +K+ +E+P+T++
Sbjct: 495 MARFSNALKDYLENPSTMI 513
>UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase family protein; n=1;
Tetrahymena thermophila SB210|Rep: pyruvate dehydrogenase
complex dihydrolipoamide acetyltransferase family protein
- Tetrahymena thermophila SB210
Length = 646
Score = 111 bits (267), Expect = 2e-23
Identities = 71/220 (32%), Positives = 112/220 (50%), Gaps = 5/220 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL ++ T ++ M ++ RK T ++ + K+ + VKA+A AL
Sbjct: 430 IAERLVQSKTTVPHFYLNIDVQMDEVLHLRK----TLNEQSTSKISVNDLIVKASALALR 485
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
D P VN+ + I + D++VAV+T GL+ P++ N + + + I LAEKAR
Sbjct: 486 DMPGVNSQWHGDHIRQFKHADVAVAVSTKTGLITPIVFNAETLGLSQISSKTKELAEKAR 545
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
G L E GGTFTISN G++G I+NPP IL + ++ + N P
Sbjct: 546 KGGLLPTEYQGGTFTISNLGMYGIDHFAAIVNPPHGTILAVGATSQKVVPDNDPHAKYPF 605
Query: 542 -----MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
M + L+ DHR++DG +L+K K +E P T++
Sbjct: 606 KTIQSMTVTLSCDHRVVDGALGAEWLQKFKGYLEKPYTML 645
>UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep:
MGC86218 protein - Xenopus laevis (African clawed frog)
Length = 478
Score = 111 bits (267), Expect = 2e-23
Identities = 72/216 (33%), Positives = 114/216 (52%), Gaps = 5/216 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++++ + ++ ++ RK+ K +IK+ + +KA A AL
Sbjct: 262 IAKRLTESKSSIPHAYATTDCNLGAVLQLRKE-----LAKDNIKVSVNDFIIKATAAALK 316
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN + +DIS+AVAT +GL+ P+I+ + +I T LA+KAR
Sbjct: 317 QMPNVNVTWNGEGATTLESIDISIAVATDRGLITPIIKQAASKGIQEIAATAKVLAQKAR 376
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAIL--GMHGI---FERPIALNGQV 526
GKL EE GG+F+ISN G+FG + +INPPQS IL G + F N Q+
Sbjct: 377 DGKLLPEEYQGGSFSISNLGMFGITGFSAVINPPQSCILAVGRSRVELGFSEGEEGNPQL 436
Query: 527 VIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+ +M + L+ D RL+D A FL ++ +E+P
Sbjct: 437 CQKQVMNVTLSSDGRLVDDELATKFLECFRKNLENP 472
>UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Chloroflexus aggregans DSM 9485|Rep:
Dihydrolipoamide S-succinyltransferase - Chloroflexus
aggregans DSM 9485
Length = 435
Score = 111 bits (267), Expect = 2e-23
Identities = 64/201 (31%), Positives = 112/201 (55%), Gaps = 5/201 (2%)
Frame = +2
Query: 59 EIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEENE-----I 223
E+D+ +MA R++ + T+ + + VKAAA AL P +N + I
Sbjct: 239 EVDVDALMALREQIAASGTR-----VSVNDLVVKAAAKALAKVPAINVSFSQTADGQPGI 293
Query: 224 IYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTF 403
+ ++I VAVA GLV PV+R+ + + I I +A +AR GK+ E++G TF
Sbjct: 294 VRHSQINIGVAVALDDGLVAPVVRDADKKSVSTISAEIRDMALRAREGKIKQNELEGATF 353
Query: 404 TISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDG 583
++N G+FG + II+ PQ+A L + + + P+ + Q+VI +M + L+ DHR+IDG
Sbjct: 354 QVTNLGMFGIIEFGSIISVPQAASLAVGTVRKVPVVRDDQIVIGQVMNLTLSADHRVIDG 413
Query: 584 REAVLFLRKIKEGVEDPATIV 646
+L+++++ +E P +I+
Sbjct: 414 AVGAQYLQELRKLLESPVSII 434
>UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA -
Drosophila melanogaster (Fruit fly)
Length = 462
Score = 111 bits (266), Expect = 2e-23
Identities = 73/199 (36%), Positives = 111/199 (55%), Gaps = 5/199 (2%)
Frame = +2
Query: 56 NEIDMSHIMAFRKKHLDTFTKKHSI-KLGLMSPFVKAAANALMDQPVVNAVIE--ENEII 226
+EIDM+ +M FR + L K++ + KL M +KAA+ AL P+VN+ ++ ++
Sbjct: 261 DEIDMTQLMQFRNQ-LQLVAKENGVPKLTFMPFCIKAASIALSKYPIVNSSLDLASESLV 319
Query: 227 YRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFT 406
++ +ISVA+ TP+GLVVP I+N Q T +I + L E+ RTG L+ + GTF+
Sbjct: 320 FKGAHNISVAIDTPQGLVVPNIKNCQTKTIIEIAKDLNALVERGRTGSLSPADFADGTFS 379
Query: 407 ISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALN--GQVVIRPMMYIALTYDHRLID 580
+SN GV G P I PQ AI G G + N +VV +M ++ + DHR+ID
Sbjct: 380 LSNIGVIGGTYTHPCIMAPQVAI-GAMGRTKAVPRFNDKDEVVKAYVMSVSWSADHRVID 438
Query: 581 GREAVLFLRKIKEGVEDPA 637
G F K+ +E+PA
Sbjct: 439 GVTMASFSNVWKQYLENPA 457
>UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase, putative; n=2; Basidiomycota|Rep:
Dihydrolipoyllysine-residue acetyltransferase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 479
Score = 111 bits (266), Expect = 2e-23
Identities = 78/221 (35%), Positives = 111/221 (50%), Gaps = 6/221 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTK--KHSIKLGLMSPFVKAAANA 175
I +RL +++ E++M ++ R + F K + KL + VKAA+ A
Sbjct: 263 IGKRLTESKQQLPHYYVTVEVNMDRVLKLR----EVFNKAGESKTKLSVNDFIVKAASLA 318
Query: 176 LMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
L D P N+ I DI VAVATP GL+ P+I++V A I LA +
Sbjct: 319 LADVPEANSAWLGETIRTYKKADICVAVATPNGLITPIIKDVGAKGLATISAETKALASR 378
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFER----PIALNGQ 523
AR GKL EE GG+FTISN G+FG T IINPPQS IL + + P G
Sbjct: 379 ARDGKLKPEEYQGGSFTISNLGMFGVDEFTAIINPPQSCILAVGKTTTKLELAPEDPKGF 438
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
++ +M + L+ DHR +DG +L+ +E +E P T +
Sbjct: 439 KAVQ-VMKVTLSADHRTVDGAVGARWLKAFREYMEQPLTFM 478
>UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Thermoplasmatales|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Picrophilus torridus
Length = 386
Score = 111 bits (266), Expect = 2e-23
Identities = 65/182 (35%), Positives = 105/182 (57%), Gaps = 1/182 (0%)
Frame = +2
Query: 92 KKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI-EENEIIYRDYVDISVAVATP 268
+K +D ++KK + S F KA A + P +NA+ ++ + +I +AV +P
Sbjct: 205 EKAIDYYSKKGYVSF--TSFFAKACTIAFKEFPKMNALYNDDGTYTIKKRYNIGIAVDSP 262
Query: 269 KGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTP 448
GL V V+++V + +I + I LAEKAR+ KL ++++ TF+++N G G + TP
Sbjct: 263 YGLTVVVVKDVDKKSIFEISMEIRELAEKARSNKLEMDDVRDSTFSVTNIGAIGGIYSTP 322
Query: 449 IINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
IIN P+ AIL ++ ++G +R +Y+ L DHRLIDG EA F++KIKE +E
Sbjct: 323 IINYPEVAILAVN--TRTNAFIDGS--MRSGVYVTLACDHRLIDGAEAARFIKKIKEIIE 378
Query: 629 DP 634
P
Sbjct: 379 QP 380
>UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=2; Dictyostelium
discoideum|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Dictyostelium
discoideum (Slime mold)
Length = 592
Score = 111 bits (266), Expect = 2e-23
Identities = 64/180 (35%), Positives = 101/180 (56%), Gaps = 5/180 (2%)
Frame = +2
Query: 122 HSIKLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNV 301
+++K+ + VKA+ AL D PVVN+ + I +DI+VAV TP+GL P++R V
Sbjct: 414 NTVKISVNDFIVKASLPALRDNPVVNSTWTDQFIRRYHNIDINVAVNTPQGLFTPIVRGV 473
Query: 302 QNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILG 481
I ++ LAEKA+ GKL E + GTFTISN G+ G +INPPQ+AIL
Sbjct: 474 DMKGLNSISTSVKQLAEKAQNGKLHPSEFESGTFTISNLGMLGIKQFAAVINPPQAAILA 533
Query: 482 MHGIFERPIALNGQVVIRP-----MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ + ++ ++ P ++ + L+ DHR+IDG +L+ K+ VE+P ++
Sbjct: 534 L--VPQKLVSFLSNKPDSPYETATILSVTLSCDHRVIDGAVGAEWLKSFKDYVENPIKLI 591
>UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X
component, mitochondrial precursor; n=26; Amniota|Rep:
Pyruvate dehydrogenase protein X component,
mitochondrial precursor - Homo sapiens (Human)
Length = 501
Score = 110 bits (264), Expect = 4e-23
Identities = 72/217 (33%), Positives = 117/217 (53%), Gaps = 6/217 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL ++++T + D+ ++ R+ + K IK+ + +KAAA L
Sbjct: 287 IAKRLTESKSTVPHAYATADCDLGAVLKVRQDLV-----KDDIKVSVNDFIIKAAAVTLK 341
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN + ++DISVAVAT KGL+ P+I++ +I ++ L++KAR
Sbjct: 342 QMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKAR 401
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAL------NGQ 523
GKL EE GG+F+ISN G+FG T +INPPQ+ IL + G F + L N +
Sbjct: 402 DGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAV-GRFRPVLKLTEDEEGNAK 460
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+ R ++ + ++ D R++D A FL+ K +E+P
Sbjct: 461 LQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>UniRef50_A0NRH8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2 subunit; n=1; Stappia aggregata IAM
12614|Rep: Branched-chain alpha-keto acid dehydrogenase
E2 subunit - Stappia aggregata IAM 12614
Length = 301
Score = 109 bits (262), Expect = 7e-23
Identities = 72/202 (35%), Positives = 106/202 (52%), Gaps = 2/202 (0%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
AQ + A +T + +M+ I A RK+ L T + +KL ++ KA + AL +
Sbjct: 86 AQNMAAAHRLIPAVTHHDRAEMTAIEALRKQ-LRTEAGERGVKLTALAFHAKALSKALRE 144
Query: 185 QPVVNAVIEEN--EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKA 358
P NA + + + +DYV + VAV T GL+VPVIR+V I IA LA +A
Sbjct: 145 FPKFNASLSSDGKTLFLKDYVHLGVAVDTAHGLMVPVIRDVDRKGLWQIAAEIADLASRA 204
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRP 538
K+ +EM G + TI+N G G TPI+NPP+ AILG+ P+
Sbjct: 205 LERKVRPDEMGGASMTITNLGGIGGTAFTPIVNPPEVAILGITRTELAPVWDGETFQPVQ 264
Query: 539 MMYIALTYDHRLIDGREAVLFL 604
M+ + L+YDHR+I+G +A FL
Sbjct: 265 MVPLDLSYDHRVINGADAARFL 286
>UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Chlamydomonas reinhardtii|Rep: Dihydrolipoamide
S-acetyltransferase - Chlamydomonas reinhardtii
Length = 643
Score = 109 bits (262), Expect = 7e-23
Identities = 64/170 (37%), Positives = 92/170 (54%), Gaps = 2/170 (1%)
Frame = +2
Query: 131 KLGLMSPFVKAAANALMDQPVVNAVIEENEIIYRDY--VDISVAVATPKGLVVPVIRNVQ 304
K+ + ++A A AL D P N +E R + VDISVAVAT +GL+ P++R
Sbjct: 465 KVSVNDCVLRAVALALRDVPAANVHWDEAAGDVRAFGGVDISVAVATERGLITPIVRAAD 524
Query: 305 NMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGM 484
+ + LA KA+ KL EE GG+FT+SN G++G + IINPPQ+AIL +
Sbjct: 525 VKGLLAVSREVRALALKAKDNKLKPEEFTGGSFTVSNLGMYGLTHFSAIINPPQAAILAV 584
Query: 485 HGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
G ER + + GQ +R M + L+ D R+ DG A L + +E P
Sbjct: 585 GGATERVVLVGGQPAVRSAMSVTLSADGRVYDGELAGAVLAAFRRHMEQP 634
>UniRef50_Q9XYS5 Cluster: Dihydrolipoyl dehydrogenase-binding
protein; n=2; Ascaris suum|Rep: Dihydrolipoyl
dehydrogenase-binding protein - Ascaris suum (Pig
roundworm) (Ascaris lumbricoides)
Length = 368
Score = 107 bits (258), Expect = 2e-22
Identities = 73/217 (33%), Positives = 109/217 (50%), Gaps = 1/217 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +++ +ID ++ R K KK I + + +KA A AL
Sbjct: 148 IARRLCESKQGIPHTYAIQKIDSDNVNKLRAK-----LKKEGISVSINDFIIKACACALR 202
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +N ++ VDISVAVATP GL+ P++ + + I + LA+KAR
Sbjct: 203 AVPELNVKWMKDHAEALPNVDISVAVATPAGLITPIVFKADTLGVSQIGAKVRELAKKAR 262
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMG-TPIINPPQSAILGMHGIFERPIALNGQVVIRP 538
KLT+EE GGTFT+SN G++GS+ T IINPPQ+AI+ + G + L +
Sbjct: 263 ANKLTLEEFQGGTFTVSNLGMYGSISHFTAIINPPQAAIMAIGGGIDE---LETDLSSTN 319
Query: 539 MMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVA 649
+ L +D R I +A FL ++P +VA
Sbjct: 320 RFQVTLCFDGRAITVPDAHRFLEHFAMTFKEPDLMVA 356
>UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.
CcI3|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 524
Score = 107 bits (257), Expect = 3e-22
Identities = 54/144 (37%), Positives = 84/144 (58%)
Frame = +2
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
EI D V++ +AVA P+GLVVP I + + + +AGL AR +L+ ++ GG
Sbjct: 379 EIHVYDRVNLGIAVAGPRGLVVPTIPDAGRLDVVGLAHALAGLTTAARADRLSPADLRGG 438
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
T TI+N GV G +GTPI+NP ++AIL + I P GQ+ +R ++ +AL++DHR++
Sbjct: 439 TITITNVGVLGVDIGTPILNPGEAAILALGSIRPMPWVHEGQLTVRTVVQLALSFDHRIV 498
Query: 578 DGREAVLFLRKIKEGVEDPATIVA 649
DG L + + DP +A
Sbjct: 499 DGALGSAVLADVGAVITDPTVALA 522
>UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Frankia|Rep: Biotin/lipoyl
attachment:Catalytic domain of components of various
dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
Length = 585
Score = 107 bits (257), Expect = 3e-22
Identities = 62/207 (29%), Positives = 108/207 (52%), Gaps = 6/207 (2%)
Frame = +2
Query: 47 TTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVI------ 208
T F +D++ MA R++ + I++ + KA A+ P++N+
Sbjct: 378 TEFLSVDVTETMAARER-IAALPDFAGIRVTPLLLVAKALLTAVRRHPMINSTWVGDTSG 436
Query: 209 EENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEM 388
E EI + +++ +AVA P+GLVVP I + + D+ ++ L E AR +L ++
Sbjct: 437 ENAEIQVHERINLGIAVAGPRGLVVPNIPDAGSRGLVDLARSLHSLTEAARADRLRPADL 496
Query: 389 DGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDH 568
GGT TI+N GV G G P++NP ++AIL + I P G++ +R + ++AL++DH
Sbjct: 497 SGGTITITNVGVLGVDTGAPVLNPGEAAILALGAIRPAPWVHEGELAVRTVAHLALSFDH 556
Query: 569 RLIDGREAVLFLRKIKEGVEDPATIVA 649
R++DG L + + DP +A
Sbjct: 557 RVVDGELGSAVLADVAAVLADPVIALA 583
>UniRef50_A3SYT7 Cluster: Acetoin dehydrogenase E2 component; n=2;
Sulfitobacter|Rep: Acetoin dehydrogenase E2 component -
Sulfitobacter sp. NAS-14.1
Length = 223
Score = 107 bits (257), Expect = 3e-22
Identities = 75/211 (35%), Positives = 108/211 (51%), Gaps = 2/211 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA + + T A LT D + +MA K L K S++ LM V+A L
Sbjct: 14 IADAMTKSLATAAQLTHHGSADATALMA-EKTRLGAAGTKISVEDLLMLAVVRA----LK 68
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVV-PVIRNVQNMTYADIELTIAGLAEKA 358
P N +E E+ D VD+SVA+A P L+V P + M ++ LA +A
Sbjct: 69 KNPDANGRVEGREVHLSDAVDLSVAIALPGNLLVAPAMFGADAMDVTELRAARQDLAARA 128
Query: 359 RTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPI-ALNGQVVIR 535
+ KLT+ EM GGTFT+SN G+ TPIIN Q ILG+ + +R + +G + +R
Sbjct: 129 KVNKLTVTEMTGGTFTVSNLGLTRVEHFTPIINAGQICILGIGRMTDRAVRGADGGIELR 188
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVE 628
P + ++LT+DHR +DG A L I E +E
Sbjct: 189 PHVGLSLTFDHRALDGAPAGDLLTSICEEIE 219
>UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;
Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E2
subunit - Nyctotherus ovalis
Length = 485
Score = 107 bits (257), Expect = 3e-22
Identities = 67/222 (30%), Positives = 116/222 (52%), Gaps = 8/222 (3%)
Frame = +2
Query: 5 AQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMD 184
A+RL +A+ T + E ++ ++ R + K S K+ + +KA + A +
Sbjct: 268 AERLTEAKQTVPLFYVSVECEVDKLLTLRSQ----LNKIASTKISINDMLIKACSLACLK 323
Query: 185 QPVVNAVIEENEII-YRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
PV N+ + + Y+D VD+SVAV TP GL+ P++ + I L KA+
Sbjct: 324 VPVTNSSWMGDFVRRYKD-VDMSVAVQTPNGLITPIVPRANLKGFEQIAKITKELIAKAK 382
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIA-------LNG 520
G L E+ GGTFTISN G++G PI+NPPQ+ ILG+ + ++ + +
Sbjct: 383 DGTLKPEQFIGGTFTISNAGMYGISQLIPIVNPPQACILGVSAVEKKVVVDEAKNEHMPA 442
Query: 521 QVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
+ I M ++L+ DHR++DG + ++ K+ +E+PA ++
Sbjct: 443 PLRIASKMTVSLSCDHRVVDGAGGAEWTQEFKKLIENPALMM 484
>UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2
component; n=3; Bacteria|Rep: Pyruvate dehydrogenase
complex E2 component - Vesicomyosocius okutanii subsp.
Calyptogena okutanii (strain HA)
Length = 507
Score = 107 bits (256), Expect = 4e-22
Identities = 61/192 (31%), Positives = 108/192 (56%), Gaps = 2/192 (1%)
Frame = +2
Query: 44 LTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALMDQPVVNAVIEEN-- 217
+T F+E++++ + A+R++ K + IKL + +KA L + NA ++E+
Sbjct: 311 VTQFDEVNINQMEAYRQEQ-----KANGIKLTPLVFIMKALVRTLKNHLRFNASLDESGE 365
Query: 218 EIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGG 397
+I + Y ++ +A+ TPKGL+VPVIR+V+ + D+ + ++ AR KL +M G
Sbjct: 366 NLIIKKYFNLGIAMDTPKGLIVPVIRDVEKKSLTDLAKELFETSKNARENKLKPADMQGS 425
Query: 398 TFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLI 577
TIS+ G G TPI+N P+ AILG+ + +P + + +AL+YDHR+I
Sbjct: 426 GLTISSLGGIGGTQFTPIVNAPEVAILGISRSYFKPTWDGENFIPTLTLPLALSYDHRVI 485
Query: 578 DGREAVLFLRKI 613
DG + F+ ++
Sbjct: 486 DGAQGGRFMAEL 497
>UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein - Yarrowia lipolytica
(Candida lipolytica)
Length = 466
Score = 107 bits (256), Expect = 4e-22
Identities = 64/180 (35%), Positives = 100/180 (55%), Gaps = 5/180 (2%)
Frame = +2
Query: 131 KLGLMSPFVKAAANALMDQPVVNAVIE----ENEIIYRDYVDISVAVATPKGLVVPVIRN 298
K+ M F+KA + AL D P+VNA ++ + ++ RDY +IS+A+ TP GL+VP I+N
Sbjct: 286 KISYMPFFIKALSLALKDYPMVNAKVDLSGDKPAVLMRDYHNISIAMDTPNGLLVPTIKN 345
Query: 299 VQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAIL 478
VQ+ T +I + L E GKL+ +++ GGT +ISN G G +P+I Q AI+
Sbjct: 346 VQDKTIVEIAADLQRLQELGMAGKLSRDDLTGGTISISNIGNVGGTYLSPVIVSEQVAIV 405
Query: 479 GMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
G+ + P G +V ++ + + DHR++DG L K K V DP ++ L
Sbjct: 406 GLGKARKLPRYNSQGDIVPEQIINASWSGDHRVLDGMTMALMADKWKAYVVDPKAMLLQL 465
>UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=40; Eukaryota|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Neurospora crassa
Length = 458
Score = 107 bits (256), Expect = 4e-22
Identities = 66/221 (29%), Positives = 116/221 (52%), Gaps = 6/221 (2%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA RLK++ N + +S ++ R+ + ++ KL + +KA A
Sbjct: 239 IAARLKESVTENPHFFVSTNLSVSKLLKLRQALNSSADGRY--KLSVNDFLIKAMGIASK 296
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P VN+ + I + VD+SVAVATP GL+ P+++ V+ I + LA+KAR
Sbjct: 297 RVPTVNSSWRDGVIRQFETVDVSVAVATPNGLITPIVKGVEGKGLESISAAVKELAKKAR 356
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMG-TPIINPPQSAILGMHGIFERPIALNGQ----- 523
GKL EE GG+ +ISN G+ ++ T IINPPQ+AIL + + + + +
Sbjct: 357 DGKLKPEEYQGGSISISNMGMNPAVQSFTAIINPPQAAILAVGAPQKVAVPVENEDGTTG 416
Query: 524 VVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIV 646
V + + ++DH+++DG ++R++K+ +E+P ++
Sbjct: 417 VSWDEQIIVTASFDHKVVDGAVGAEWIRELKKVIENPLELL 457
>UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=3;
Saccharomycetales|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 482
Score = 106 bits (255), Expect = 5e-22
Identities = 76/218 (34%), Positives = 111/218 (50%), Gaps = 7/218 (3%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
I +RL + ++I +S ++ R+ T K+ KL + VKA A
Sbjct: 263 IGERLLQSTQGIPSYIVSSKISISKLLKLRQSLNATANDKY--KLSINDLLVKAITVAAK 320
Query: 182 DQPVVNAVIEENEIIYRDY--VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
P NA NE + R + VD+SVAVATP GL+ P+++N + + I I L ++
Sbjct: 321 RVPDANAYWLPNENVIRKFKNVDVSVAVATPTGLLTPIVKNCEAKGLSQISNEIKELVKR 380
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSL-MGTPIINPPQSAILGMHGI----FERPIALNG 520
AR KL EE GGT ISN G+ ++ M T IINPPQS IL + + E A NG
Sbjct: 381 ARINKLAPEEFQGGTICISNMGMNNAVNMFTSIINPPQSTILAIATVERVAVEDAAAENG 440
Query: 521 QVVIRPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+ I T+DHR IDG + F++++K +E+P
Sbjct: 441 -FSFDNQVTITGTFDHRTIDGAKGAEFMKELKTVIENP 477
>UniRef50_UPI000038D51F Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1; Nostoc
punctiforme PCC 73102|Rep: COG0508:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide acyltransferase (E2) component, and
related enzymes - Nostoc punctiforme PCC 73102
Length = 367
Score = 105 bits (253), Expect = 8e-22
Identities = 66/182 (36%), Positives = 98/182 (53%), Gaps = 3/182 (1%)
Frame = +2
Query: 101 LDTFTKKHSIKLGLMSPFVKAAANALMDQPVV-NAVIEENEIIYRDYVDISVAVATPKGL 277
L + KKH I +GL +K A L + P ++I++N + + +I V + KGL
Sbjct: 186 LSDYGKKHDIIIGLPELLIKITATLLSEFPFFFGSLIDDNRFMPGEVANIGVTLDLGKGL 245
Query: 278 VVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIIN 457
+PVI+NV ++ ADI + KA G+ EE++ G ++S SL+ PII
Sbjct: 246 FIPVIKNVGEISLADIANKLMEFRLKAMRGQFNEEELNQGNISLSINMDKDSLVTIPIIL 305
Query: 458 PPQSAILGMHGIFERPIALNGQVVIRPMMYI--ALTYDHRLIDGREAVLFLRKIKEGVED 631
P QS +L + GI E + L + ++ YI L YDHR+I+GREA FL KIK VE
Sbjct: 306 PSQSCMLSLGGIQEE-LYLGSEQNVKNRSYINLGLAYDHRVINGREAAQFLTKIKTKVEQ 364
Query: 632 PA 637
P+
Sbjct: 365 PS 366
>UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase (E2)
component, and related enzyme; n=1; marine gamma
proteobacterium HTCC2080|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzyme - marine gamma
proteobacterium HTCC2080
Length = 388
Score = 105 bits (253), Expect = 8e-22
Identities = 65/209 (31%), Positives = 107/209 (51%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL +A+ T + + +MA H T K+ + V ALM
Sbjct: 182 IARRLTEAKQTIPHFYLSADYALDGLMA----HRQTLNGSGDTKVSVNDLLVWCVGQALM 237
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
+P VN + ++I + +I+VA+AT GL I V+ + A++ LAEKAR
Sbjct: 238 REPRVNVNLVGDDIHQFEAANIAVAIATDDGLYPATIPGVEAKSPAEVAQATGALAEKAR 297
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
+ LT E++ GG+FT+SN G++G T IINPP AIL + + + +G+ I +
Sbjct: 298 SNSLTKEDISGGSFTVSNLGMYGISEFTAIINPPMGAILALGKAEPKVVVKDGEQSIATV 357
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVE 628
+ L+ DHR+IDG F+ +++ ++
Sbjct: 358 LTATLSCDHRVIDGAVGAQFMAALRDVID 386
>UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 396
Score = 105 bits (253), Expect = 8e-22
Identities = 73/218 (33%), Positives = 117/218 (53%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHSIKLGLMSPFVKAAANALM 181
IA+RL ++ T + + M +++ K HL K+ + + + VK AA L
Sbjct: 189 IAKRLLKSKTTIPHVYASTDCVMDNLLQL-KSHL----KERGLTVSVNDLLVKVAAVCLR 243
Query: 182 DQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKAR 361
P +NAV EI Y +D++V VAT G++ PVIRN + + I L +A +AR
Sbjct: 244 KVPEMNAVWNGKEIEYLKDIDLAVDVATDVGIITPVIRNAAYLDLSQISLVAHDIATRAR 303
Query: 362 TGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPM 541
KL E GG+ T+SN G+FG + IINP Q++IL + G ++ +GQ ++ +
Sbjct: 304 DNKLHEHEFHGGSLTLSNLGMFGVTEFSAIINPLQASILAV-GATRLSVSTDGQ--LQNV 360
Query: 542 MYIALTYDHRLIDGREAVLFLRKIKEGVEDPATIVAGL 655
+ + L+ D R++D A +L K G+E+PA +AGL
Sbjct: 361 ITVKLSCDARVVDNELASRWLETFKLGIENPA--LAGL 396
>UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase; n=3;
Staphylococcus|Rep: Acetoin dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 425
Score = 105 bits (252), Expect = 1e-21
Identities = 62/213 (29%), Positives = 111/213 (52%), Gaps = 2/213 (0%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKK--HSIKLGLMSPFVKAAANA 175
IAQ ++ + N+ A LT ++D ++ F K L T K+ +KL + + KA A
Sbjct: 209 IAQNMRQSLNSTAQLTLHRKVDADRLLDF-KDRLATELKQADQDVKLTVTTLLAKAVVLA 267
Query: 176 LMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEK 355
L + +NA E+ E+ + V + +A + +GL+VPVI + + + I AE
Sbjct: 268 LKEYGAMNARYEQGELTEYEDVHLGIATSLDEGLMVPVINHADTKSIGTLAHEIKSSAEA 327
Query: 356 ARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIR 535
R G +++G TFTI+N G G TPI+N ++ ILG+ + + + +
Sbjct: 328 VREGNTGAVQLEGATFTITNMGASGIEYFTPILNLGETGILGVGALTKEVVLEADNIKQV 387
Query: 536 PMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+ ++LT+DH+++DG A FL+ + + +E+P
Sbjct: 388 SKIPLSLTFDHQILDGAGAADFLKVLAKYIENP 420
>UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2
component PdhC; n=3; Mycobacterium|Rep: Dihydrolipoamide
S-acetyltransferase E2 component PdhC - Mycobacterium
ulcerans (strain Agy99)
Length = 389
Score = 105 bits (252), Expect = 1e-21
Identities = 54/139 (38%), Positives = 78/139 (56%)
Frame = +2
Query: 239 VDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNG 418
V + VAT +GL+VPVI + MT ++ A L AR G L ++ G TFT+SN
Sbjct: 251 VHLGFGVATERGLLVPVIADAHRMTTRELVCRAAELITGAREGTLAPGQLRGWTFTVSNY 310
Query: 419 GVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVL 598
G G G P+IN P +AILGM I RP+ +VV+RP M + +DHR+ DG +
Sbjct: 311 GALGVDDGVPVINHPDAAILGMGSIKPRPVVRGDEVVVRPTMSLTCVFDHRVADGAQVAR 370
Query: 599 FLRKIKEGVEDPATIVAGL 655
F+ +++ +E P T + L
Sbjct: 371 FICELRGLIEAPETALLDL 389
>UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=29; Alphaproteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rhizobium meliloti
(Sinorhizobium meliloti)
Length = 447
Score = 105 bits (251), Expect = 1e-21
Identities = 62/214 (28%), Positives = 106/214 (49%), Gaps = 3/214 (1%)
Frame = +2
Query: 2 IAQRLKDAQNTNAMLTTFNEIDMSHIMAFRKKHLDTFTKKHS---IKLGLMSPFVKAAAN 172
IA+RL +++ T + ++ +MA R + +K KL + +KA A
Sbjct: 229 IAKRLVESKQTIPHFYVSVDCELDALMALRAQLNAAAPEKDGKPVYKLSVNDMVIKALAL 288
Query: 173 ALMDQPVVNAVIEENEIIYRDYVDISVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAE 352
AL D P N + ++ + D+ VAV+ P GL+ P++R + + + I + L +
Sbjct: 289 ALRDVPDANVSWTDQNMVKHKHADVGVAVSIPGGLITPIVRQAELKSLSAISNEMKDLGK 348
Query: 353 KARTGKLTIEEMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIALNGQVVI 532
+A+ KL EE GGT +SN G+ G ++NPP + IL + +R + N ++VI
Sbjct: 349 RAKERKLKPEEYQGGTTAVSNMGMMGVKDFAAVVNPPHATILAVGAGEDRVVVRNKEMVI 408
Query: 533 RPMMYIALTYDHRLIDGREAVLFLRKIKEGVEDP 634
+M + L+ DHR +DG L K +E+P
Sbjct: 409 ANVMTVTLSTDHRCVDGALGAELLAAFKRYIENP 442
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 733,898,821
Number of Sequences: 1657284
Number of extensions: 15688363
Number of successful extensions: 49997
Number of sequences better than 10.0: 383
Number of HSP's better than 10.0 without gapping: 47184
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 49693
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 58853922985
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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