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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= maV30192
         (644 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D55D4F Cluster: PREDICTED: similar to CG6020-PA;...   249   5e-65
UniRef50_Q9VPE2 Cluster: CG6020-PA; n=7; Endopterygota|Rep: CG60...   227   2e-58
UniRef50_A7SNV3 Cluster: Predicted protein; n=1; Nematostella ve...   191   1e-47
UniRef50_Q5DCH0 Cluster: SJCHGC05906 protein; n=1; Schistosoma j...   167   3e-40
UniRef50_Q9N3H3 Cluster: Putative uncharacterized protein; n=2; ...   166   5e-40
UniRef50_Q16795 Cluster: NADH dehydrogenase [ubiquinone] 1 alpha...   165   8e-40
UniRef50_Q4PHN2 Cluster: Putative uncharacterized protein; n=1; ...   163   2e-39
UniRef50_A4S3R8 Cluster: Predicted protein; n=1; Ostreococcus lu...   154   2e-36
UniRef50_Q6C7X4 Cluster: Similar to tr|Q86ZJ8 Podospora anserina...   145   9e-34
UniRef50_UPI0000E48350 Cluster: PREDICTED: similar to MGC64316 p...   144   1e-33
UniRef50_A2QSH0 Cluster: Catalytic activity: NADH + ubiquinone =...   141   1e-32
UniRef50_P25284 Cluster: NADH-ubiquinone oxidoreductase 40 kDa s...   140   3e-32
UniRef50_A7Q1K0 Cluster: Chromosome chr7 scaffold_44, whole geno...   134   2e-30
UniRef50_Q6V506 Cluster: Putative NADH:ubiquinone oxidoreductase...   134   2e-30
UniRef50_Q5KJ08 Cluster: NADH dehydrogenase (Ubiquinone), putati...   130   4e-29
UniRef50_Q559Z0 Cluster: Putative uncharacterized protein; n=2; ...   126   3e-28
UniRef50_Q5AJA9 Cluster: Potential mitochondrial Complex I, 40kd...   122   7e-27
UniRef50_UPI00006CB9E4 Cluster: hypothetical protein TTHERM_0055...    91   2e-17
UniRef50_A4GHP1 Cluster: NADH-ubiquinone oxidoreductase; n=2; Ba...    76   6e-13
UniRef50_Q2RYH4 Cluster: 3-beta-hydroxy-delta(5)-steroid dehydro...    75   2e-12
UniRef50_A7HPI7 Cluster: NAD-dependent epimerase/dehydratase; n=...    73   5e-12
UniRef50_Q0BUA2 Cluster: NADH-ubiquinone oxidoreductase 39-40 kD...    71   2e-11
UniRef50_Q2GE21 Cluster: NADH-ubiquinone oxidoreductase family p...    71   3e-11
UniRef50_Q1GCR4 Cluster: 3-beta hydroxysteroid dehydrogenase/iso...    70   6e-11
UniRef50_Q3YT69 Cluster: NADH-ubiquinone oxidoreductase, putativ...    69   1e-10
UniRef50_Q3JEV6 Cluster: NAD-dependent epimerase/dehydratase; n=...    66   9e-10
UniRef50_Q1GR77 Cluster: 3-beta hydroxysteroid dehydrogenase/iso...    65   2e-09
UniRef50_A7DMA8 Cluster: NAD-dependent epimerase/dehydratase; n=...    65   2e-09
UniRef50_A4WW99 Cluster: NADH dehydrogenase; n=5; Rhodobacterale...    62   8e-09
UniRef50_Q38CX2 Cluster: Putative uncharacterized protein; n=5; ...    61   2e-08
UniRef50_Q4FNB8 Cluster: Probable NADH-ubiquinone oxireductase; ...    61   3e-08
UniRef50_A0BZW4 Cluster: Chromosome undetermined scaffold_14, wh...    60   4e-08
UniRef50_Q1GZ10 Cluster: NAD-dependent epimerase/dehydratase; n=...    59   8e-08
UniRef50_Q2GII8 Cluster: NADH-ubiquinone oxidoreductase family p...    57   4e-07
UniRef50_Q98CD7 Cluster: NADH dehydrogenase (Ubiquinone) 1 alpha...    56   6e-07
UniRef50_Q0ACP9 Cluster: NAD-dependent epimerase/dehydratase; n=...    56   7e-07
UniRef50_A7BKW7 Cluster: NAD-dependent epimerase/dehydratase; n=...    54   2e-06
UniRef50_UPI0000E87D4F Cluster: NAD-dependent epimerase/dehydrat...    54   3e-06
UniRef50_Q0F0X9 Cluster: NAD-dependent epimerase/dehydratase; n=...    52   1e-05
UniRef50_A6FZ88 Cluster: Probable NADH-ubiquinone oxidoreductase...    52   1e-05
UniRef50_A5FQ11 Cluster: NAD-dependent epimerase/dehydratase; n=...    52   2e-05
UniRef50_Q1PXS0 Cluster: Similar to dehydratase OleE [Streptomyc...    50   5e-05
UniRef50_A6GU58 Cluster: NAD-dependent epimerase/dehydratase; n=...    50   6e-05
UniRef50_A5P8M1 Cluster: NADH ubiquinone oxidoreductase, putativ...    48   1e-04
UniRef50_Q6G583 Cluster: NADH-ubiquinone oxidoreductase; n=3; Ba...    46   6e-04
UniRef50_Q3JE30 Cluster: NAD-dependent epimerase/dehydratase; n=...    46   6e-04
UniRef50_Q125I6 Cluster: NAD-dependent epimerase/dehydratase; n=...    46   6e-04
UniRef50_Q5FPV9 Cluster: Putative oxidoreductase; n=1; Gluconoba...    46   8e-04
UniRef50_Q2Y682 Cluster: NAD-dependent epimerase/dehydratase; n=...    46   8e-04
UniRef50_Q1YEV9 Cluster: NADH-ubiquinone oxidoreductase; n=7; Al...    46   0.001
UniRef50_A1VGT7 Cluster: NAD-dependent epimerase/dehydratase; n=...    45   0.001
UniRef50_UPI0000F21730 Cluster: PREDICTED: hypothetical protein;...    45   0.002
UniRef50_Q39C42 Cluster: NAD-dependent epimerase/dehydratase; n=...    44   0.002
UniRef50_A1WZI3 Cluster: NAD-dependent epimerase/dehydratase; n=...    44   0.002
UniRef50_Q4UMY6 Cluster: Putative oxidoreductase protein; n=15; ...    44   0.003
UniRef50_Q31J38 Cluster: NAD-dependent epimerase/dehydratase; n=...    44   0.003
UniRef50_Q2S702 Cluster: Predicted nucleoside-diphosphate-sugar ...    43   0.006
UniRef50_Q8KDL0 Cluster: 3-beta hydroxysteroid dehydrogenase/iso...    42   0.010
UniRef50_Q67KJ4 Cluster: Putative oxidoreductase; n=1; Symbiobac...    41   0.022
UniRef50_A3ES38 Cluster: Putative nucleoside-diphosphate-sugar e...    41   0.022
UniRef50_Q9HNV3 Cluster: NADH dehydrogenase/oxidoreductase-like ...    41   0.029
UniRef50_A3YG10 Cluster: Putative uncharacterized protein; n=1; ...    40   0.051
UniRef50_A4T0E5 Cluster: NAD-dependent epimerase/dehydratase; n=...    40   0.068
UniRef50_Q2W604 Cluster: Predicted nucleoside-diphosphate-sugar ...    39   0.090
UniRef50_Q1LGK6 Cluster: NAD-dependent epimerase/dehydratase; n=...    39   0.090
UniRef50_Q11Z70 Cluster: Nucleoside-diphosphate-sugar epimerase;...    39   0.12 
UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5; Halobacte...    39   0.12 
UniRef50_Q7NWF7 Cluster: Probable NADH-ubiquinone oxidoreductase...    38   0.16 
UniRef50_Q746J9 Cluster: NADH-ubiquinone oxidoreductase 39 kDa s...    38   0.16 
UniRef50_Q5NR25 Cluster: Predicted nucleoside-diphosphate-sugar ...    38   0.16 
UniRef50_UPI00015BC9D3 Cluster: UPI00015BC9D3 related cluster; n...    38   0.21 
UniRef50_Q9X9X6 Cluster: Putative uncharacterized protein SCO189...    38   0.27 
UniRef50_A7H9M3 Cluster: NAD-dependent epimerase/dehydratase pre...    38   0.27 
UniRef50_A6G7N0 Cluster: Oxidoreductase, short chain dehydrogena...    38   0.27 
UniRef50_A0L6A2 Cluster: NAD-dependent epimerase/dehydratase; n=...    38   0.27 
UniRef50_Q3SGD6 Cluster: Nucleoside-diphosphate-sugar epimerases...    37   0.36 
UniRef50_Q1K3T7 Cluster: NAD-dependent epimerase/dehydratase; n=...    37   0.36 
UniRef50_A3WA10 Cluster: Predicted nucleoside-diphosphate-sugar ...    37   0.36 
UniRef50_Q5P3S8 Cluster: Predicted nucleoside-diphosphate-sugar ...    37   0.48 
UniRef50_Q9HCX3 Cluster: Zinc finger protein 304; n=4; Homo sapi...    37   0.48 
UniRef50_Q2FQM3 Cluster: Putative uncharacterized protein precur...    36   0.63 
UniRef50_Q73MR8 Cluster: Epimerase/dehydratase, putative; n=2; B...    36   0.84 
UniRef50_A0QDT4 Cluster: Putative uncharacterized protein; n=1; ...    36   0.84 
UniRef50_Q0ANG5 Cluster: NAD-dependent epimerase/dehydratase pre...    36   1.1  
UniRef50_Q12VM5 Cluster: NAD-dependent epimerase/dehydratase; n=...    36   1.1  
UniRef50_Q9A4D7 Cluster: Putative uncharacterized protein; n=1; ...    35   1.5  
UniRef50_Q0C1U1 Cluster: Putative UDP-glucose 4-epimerase; n=1; ...    35   1.5  
UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellu...    35   1.9  
UniRef50_Q67SF4 Cluster: Putative NADH-ubiquinone oxidoreductase...    35   1.9  
UniRef50_Q5FL85 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    35   1.9  
UniRef50_Q489H0 Cluster: Pseudouridine synthase; n=1; Colwellia ...    35   1.9  
UniRef50_Q11DG7 Cluster: NAD-dependent epimerase/dehydratase; n=...    35   1.9  
UniRef50_A5V7D1 Cluster: Short-chain dehydrogenase/reductase SDR...    35   1.9  
UniRef50_A1WAD5 Cluster: NAD-dependent epimerase/dehydratase; n=...    35   1.9  
UniRef50_Q048B8 Cluster: Glycerophosphoryl diester phosphodieste...    34   2.6  
UniRef50_A7BY73 Cluster: NAD-dependent epimerase/dehydratase; n=...    34   2.6  
UniRef50_A3TUE1 Cluster: Putative uncharacterized protein; n=3; ...    34   2.6  
UniRef50_Q4XFA1 Cluster: Putative uncharacterized protein; n=1; ...    34   2.6  
UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetell...    34   3.4  
UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=...    34   3.4  
UniRef50_O66532 Cluster: NADH dehydrogenase; n=2; Aquifex|Rep: N...    34   3.4  
UniRef50_A1ULW0 Cluster: NAD-dependent epimerase/dehydratase; n=...    34   3.4  
UniRef50_A0LUB4 Cluster: Uncharacterised conserved protein UCP03...    34   3.4  
UniRef50_Q3KN81 Cluster: Leucoanthocyanidin reductase; n=3; Sper...    34   3.4  
UniRef50_Q89WS9 Cluster: Bll0599 protein; n=1; Bradyrhizobium ja...    33   4.5  
UniRef50_Q6LH31 Cluster: Putative uncharacterized protein CT0995...    33   4.5  
UniRef50_Q2RKH0 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   4.5  
UniRef50_A3ZLP8 Cluster: NAD-dependent epimerase/dehydratase fam...    33   4.5  
UniRef50_A0YNT9 Cluster: Putative uncharacterized protein; n=1; ...    33   4.5  
UniRef50_A0VU05 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   4.5  
UniRef50_Q8FSM1 Cluster: Putative UDP-galactose 4-epimerase; n=1...    33   5.9  
UniRef50_Q7WTE7 Cluster: NanG4; n=1; Streptomyces nanchangensis|...    33   5.9  
UniRef50_Q1PXL6 Cluster: Strongly similar to leucine dehydrogena...    33   5.9  
UniRef50_Q1IZY4 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   5.9  
UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   5.9  
UniRef50_A6EIS2 Cluster: Probable dehydrogenase/reductase; n=1; ...    33   5.9  
UniRef50_A1VMB7 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   5.9  
UniRef50_Q9FRM0 Cluster: NADPH oxidoreductase, putative; 12234-1...    33   5.9  
UniRef50_Q23086 Cluster: Putative uncharacterized protein; n=2; ...    33   5.9  
UniRef50_P52577 Cluster: Isoflavone reductase homolog P3; n=30; ...    33   5.9  
UniRef50_UPI00015B4F2F Cluster: PREDICTED: similar to hydroxyste...    33   7.8  
UniRef50_UPI0000DAE763 Cluster: hypothetical protein Rgryl_01001...    33   7.8  
UniRef50_UPI0000499078 Cluster: acyl-CoA synthetase; n=1; Entamo...    33   7.8  
UniRef50_Q9L3U6 Cluster: Putative TDP-glucose dehydratase; n=1; ...    33   7.8  
UniRef50_Q0LC55 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   7.8  
UniRef50_Q0AIT5 Cluster: NAD-dependent epimerase/dehydratase; n=...    33   7.8  
UniRef50_A5E1Q4 Cluster: Predicted protein; n=1; Lodderomyces el...    33   7.8  
UniRef50_Q67477 Cluster: 3 beta-hydroxysteroid dehydrogenase/Del...    33   7.8  

>UniRef50_UPI0000D55D4F Cluster: PREDICTED: similar to CG6020-PA;
           n=2; Endopterygota|Rep: PREDICTED: similar to CG6020-PA
           - Tribolium castaneum
          Length = 398

 Score =  249 bits (609), Expect = 5e-65
 Identities = 114/166 (68%), Positives = 136/166 (81%), Gaps = 1/166 (0%)
 Frame = +3

Query: 135 GSMSVVYIKAANYSSDRKP-NLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKI 311
           G + + Y+K ANYS++ K  NL+A KRGTGGRSSFNGIVATVFGC GF+GRYVCN+LGK 
Sbjct: 17  GFIGIAYVKTANYSTESKAYNLSALKRGTGGRSSFNGIVATVFGCGGFIGRYVCNRLGKN 76

Query: 312 GTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYET 491
           G+QLILPYRGD YD  RLKVCGDLGQV F P+ L DEESI K  RYSNVVINL+GRD+ET
Sbjct: 77  GSQLILPYRGDPYDVMRLKVCGDLGQVYFHPFDLRDEESIEKVCRYSNVVINLIGRDWET 136

Query: 492 KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLK 629
           +NF ++DVHV G R +A++ +  GVERFIHLS LNAEE P+ ++LK
Sbjct: 137 RNFSFDDVHVKGARLLAKVAKRSGVERFIHLSALNAEETPEAVILK 182


>UniRef50_Q9VPE2 Cluster: CG6020-PA; n=7; Endopterygota|Rep:
           CG6020-PA - Drosophila melanogaster (Fruit fly)
          Length = 416

 Score =  227 bits (555), Expect = 2e-58
 Identities = 112/151 (74%), Positives = 121/151 (80%)
 Frame = +3

Query: 192 NLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKV 371
           N AA KRGTGGRSSFNGIVATVFG TGFVGRYVCNKLGK GTQ+ILPYRGD  D  RLKV
Sbjct: 47  NPAAMKRGTGGRSSFNGIVATVFGATGFVGRYVCNKLGKSGTQMILPYRGDDSDVIRLKV 106

Query: 372 CGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARIC 551
            GDLGQVLF  Y+L D  SI  AV++SNVVINLVGRD+ETKNFK+ DVHV+G  RIARI 
Sbjct: 107 TGDLGQVLFHFYNLEDPASIRDAVKHSNVVINLVGRDFETKNFKFKDVHVNGAERIARIA 166

Query: 552 REEGVERFIHLSYLNAEEHPKPLVLKKPSAW 644
           RE GVER IHLS LN E +PK L +K  S W
Sbjct: 167 REAGVERLIHLSSLNVEANPKDLYVKGGSEW 197


>UniRef50_A7SNV3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 372

 Score =  191 bits (465), Expect = 1e-47
 Identities = 84/131 (64%), Positives = 108/131 (82%)
 Frame = +3

Query: 207 KRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLG 386
           K+GTGGRSSFNG+ ATVFG TGF+GRYV N+LG++GTQL +PYRGD +D + L++ GDLG
Sbjct: 34  KKGTGGRSSFNGVSATVFGATGFLGRYVINRLGRVGTQLTVPYRGDEHDIRHLRLMGDLG 93

Query: 387 QVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGV 566
           Q+ F  +HL DEESIAK V++SNVV+NL+GR +ET+NF + +VHVDG R IA+  +E GV
Sbjct: 94  QIDFFDFHLKDEESIAKMVKHSNVVVNLIGRGFETRNFNFEEVHVDGARTIAKAAKEAGV 153

Query: 567 ERFIHLSYLNA 599
           ER IH+S LNA
Sbjct: 154 ERLIHVSALNA 164


>UniRef50_Q5DCH0 Cluster: SJCHGC05906 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC05906 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 394

 Score =  167 bits (405), Expect = 3e-40
 Identities = 76/144 (52%), Positives = 109/144 (75%)
 Frame = +3

Query: 207 KRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLG 386
           KRGTGGR+SFNG+V TVFG TG++GR +   L K GTQ+I+PYR D +  + +KV GDLG
Sbjct: 42  KRGTGGRASFNGMVVTVFGATGYLGRVLMTHLAKTGTQIIVPYRCDPHMIRGMKVVGDLG 101

Query: 387 QVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGV 566
           Q+LF PY+L D+E + KA++YS+VVINL+G +++T+NF   +VH+D   RIA+I +E GV
Sbjct: 102 QILFLPYNLKDDECLRKAMKYSDVVINLIGTEFDTRNFTIEEVHIDAACRIAKISKEIGV 161

Query: 567 ERFIHLSYLNAEEHPKPLVLKKPS 638
           E+ +H+S L   ++P+  V +KPS
Sbjct: 162 EQLVHVSALCQNKNPQKYV-RKPS 184


>UniRef50_Q9N3H3 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 431

 Score =  166 bits (403), Expect = 5e-40
 Identities = 84/170 (49%), Positives = 112/170 (65%)
 Frame = +3

Query: 105 QATSKLLHLNGSMSVVYIKAANYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGR 284
           QA S +   N S +V   + A+         A +++G GGR+SF+G V TVFG +GF+G 
Sbjct: 14  QAVSVVGSQNFSSAVTSAENAHPEPRVSSQSAQFRKGAGGRASFSGNVVTVFGASGFLGL 73

Query: 285 YVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVI 464
            V NK  K G+Q+I+PYR D Y  +  KV G+LGQVL+ P+ L+DEESI KAV+YSNVVI
Sbjct: 74  PVVNKFAKNGSQIIIPYRQDPYYMREHKVLGELGQVLYFPFELMDEESIRKAVKYSNVVI 133

Query: 465 NLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 614
           NL+G    T  + Y DV+  G RR+ARIC+E GVE+F+HLS L A   P+
Sbjct: 134 NLIGTRVPTGKYNYYDVNDTGARRLARICKEMGVEKFVHLSALGATTQPQ 183


>UniRef50_Q16795 Cluster: NADH dehydrogenase [ubiquinone] 1 alpha
           subcomplex subunit 9, mitochondrial precursor; n=38;
           Euteleostomi|Rep: NADH dehydrogenase [ubiquinone] 1
           alpha subcomplex subunit 9, mitochondrial precursor -
           Homo sapiens (Human)
          Length = 377

 Score =  165 bits (401), Expect = 8e-40
 Identities = 78/139 (56%), Positives = 105/139 (75%)
 Frame = +3

Query: 183 RKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR 362
           R+ + A    G GGRSS +GIVATVFG TGF+GRYV N LG++G+Q+I+PYR D YD   
Sbjct: 34  RQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMH 93

Query: 363 LKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA 542
           L+  GDLGQ+LF  +   D++SI + V++SNVVINL+GRD+ETKNF + DV V   + IA
Sbjct: 94  LRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIA 153

Query: 543 RICREEGVERFIHLSYLNA 599
           ++ +E GVE+FIH+S+LNA
Sbjct: 154 QLSKEAGVEKFIHVSHLNA 172


>UniRef50_Q4PHN2 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 392

 Score =  163 bits (397), Expect = 2e-39
 Identities = 91/186 (48%), Positives = 120/186 (64%), Gaps = 2/186 (1%)
 Frame = +3

Query: 78  KMAAIALKTQATSKLLHLNGSMSVVYIKAANYSSDRKPNLAAYKRGT--GGRSSFNGIVA 251
           K A+ AL+ +A S LL   GS  V      + + +RK      K G   GGRSS +G V 
Sbjct: 11  KAASSALRFEARSSLLR--GSQVVQARNVHDLTINRKTGKPIIKSGPYGGGRSSVSGHVV 68

Query: 252 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           TVFGCTGF+GRYV N+L + G+Q+I+PYR D  + + LKV GDLGQV+   + L  +E I
Sbjct: 69  TVFGCTGFLGRYVVNRLAQKGSQVIVPYR-DEDEKRHLKVMGDLGQVVPMEWDLRHDEQI 127

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 611
            + VR+S+VV NL GR YETKNF +NDVHV G +RIA+I    GV RFIH+S+LNA+ + 
Sbjct: 128 EECVRHSDVVYNLTGRHYETKNFTFNDVHVTGAQRIAQIAEASGVGRFIHVSHLNADANS 187

Query: 612 KPLVLK 629
               L+
Sbjct: 188 PSAFLR 193


>UniRef50_A4S3R8 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 366

 Score =  154 bits (374), Expect = 2e-36
 Identities = 75/142 (52%), Positives = 101/142 (71%), Gaps = 1/142 (0%)
 Frame = +3

Query: 189 PNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLK 368
           P++ +   GTGGRSSF+GI  TVFG TGF+GRYV + + K G+++ILP R    D Q LK
Sbjct: 14  PSVTSDAVGTGGRSSFSGITCTVFGSTGFLGRYVVHHVAKSGSRMILPTRCSENDRQHLK 73

Query: 369 VCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARI 548
           V GDLGQ++   Y + DEE+I  AV  SNVVIN+VGR++ET+NF + DV+V   +++A I
Sbjct: 74  VMGDLGQIVQLDYGIRDEETIRYAVERSNVVINMVGREWETRNFSFEDVNVTFPKKLAEI 133

Query: 549 CREEGVERFIHLSYLNAEE-HP 611
           C + GV R +H+S L AEE HP
Sbjct: 134 CADVGVRRLVHVSALGAEEDHP 155


>UniRef50_Q6C7X4 Cluster: Similar to tr|Q86ZJ8 Podospora anserina;
           n=1; Yarrowia lipolytica|Rep: Similar to tr|Q86ZJ8
           Podospora anserina - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 375

 Score =  145 bits (351), Expect = 9e-34
 Identities = 70/131 (53%), Positives = 92/131 (70%)
 Frame = +3

Query: 210 RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQ 389
           +GTGGRSS  G  ATVFG  GF+G Y+  KL K GT +++PYR +    + LKV GDLG 
Sbjct: 43  KGTGGRSSRTGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYREEMAK-RHLKVTGDLGV 101

Query: 390 VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE 569
           V F    L + ESI +AVR+S++V+NL+GR+YETKNF Y DVHV+G RRIA   ++  + 
Sbjct: 102 VNFLEMDLRNLESIDEAVRHSDIVVNLIGREYETKNFNYYDVHVEGARRIAEAVKKHNIA 161

Query: 570 RFIHLSYLNAE 602
           R+IH+S  NAE
Sbjct: 162 RYIHVSAFNAE 172


>UniRef50_UPI0000E48350 Cluster: PREDICTED: similar to MGC64316
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC64316 protein -
           Strongylocentrotus purpuratus
          Length = 378

 Score =  144 bits (350), Expect = 1e-33
 Identities = 62/131 (47%), Positives = 95/131 (72%)
 Frame = +3

Query: 210 RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQ 389
           +G GGRSSF+GIVA VFG  GF+G+Y+ N+LG+ G+Q+++P+R D Y  Q +K+ GDLGQ
Sbjct: 45  KGRGGRSSFSGIVAAVFGGNGFLGKYIVNRLGREGSQVVVPHRCDEYYVQPMKLMGDLGQ 104

Query: 390 VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE 569
           ++F  Y+L   + I   V    VV+NL+ +DYET++F + D++++  R +A+IC+E GV 
Sbjct: 105 IMFRQYNLRQHDLIRDIVGNCTVVVNLLSKDYETRHFTFEDINIEAPRNLAKICKEAGVP 164

Query: 570 RFIHLSYLNAE 602
           R IH+S L A+
Sbjct: 165 RLIHVSALGAD 175


>UniRef50_A2QSH0 Cluster: Catalytic activity: NADH + ubiquinone =
           NAD+ + ubiquinol; n=4; Pezizomycotina|Rep: Catalytic
           activity: NADH + ubiquinone = NAD+ + ubiquinol -
           Aspergillus niger
          Length = 372

 Score =  141 bits (342), Expect = 1e-32
 Identities = 70/127 (55%), Positives = 86/127 (67%)
 Frame = +3

Query: 219 GGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLF 398
           GGRSS  G  ATVFG TGF+GRY+ NKL   G  +++PYR +    + LKV GDLG+V F
Sbjct: 38  GGRSSLGGHTATVFGATGFLGRYIVNKLATQGCTVVVPYREEM-TKRHLKVTGDLGRVNF 96

Query: 399 TPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFI 578
             Y L + +SI +AVR+S+VV NLVGR Y TKNF Y DVHVDG  RI     +  V+RFI
Sbjct: 97  IEYDLRNTQSIEEAVRHSDVVYNLVGRQYPTKNFSYTDVHVDGTERIVEAVAKYDVDRFI 156

Query: 579 HLSYLNA 599
           H+S  NA
Sbjct: 157 HVSSYNA 163


>UniRef50_P25284 Cluster: NADH-ubiquinone oxidoreductase 40 kDa
           subunit, mitochondrial precursor; n=17;
           Pezizomycotina|Rep: NADH-ubiquinone oxidoreductase 40
           kDa subunit, mitochondrial precursor - Neurospora crassa
          Length = 375

 Score =  140 bits (339), Expect = 3e-32
 Identities = 65/131 (49%), Positives = 92/131 (70%)
 Frame = +3

Query: 210 RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQ 389
           R  GGRSS  G  ATVFG TG +GRY+ N+L + G  +++P+R D Y+ + LKV GDLG+
Sbjct: 41  RNQGGRSSLGGHTATVFGATGQLGRYIVNRLARQGCTVVIPFR-DEYNKRHLKVTGDLGK 99

Query: 390 VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE 569
           V+   + L + +SI ++VR+S+VV NL+GRDY TKNF + DVH++G  RIA    +  V+
Sbjct: 100 VVMIEFDLRNTQSIEESVRHSDVVYNLIGRDYPTKNFSFEDVHIEGAERIAEAVAKYDVD 159

Query: 570 RFIHLSYLNAE 602
           RFIH+S  NA+
Sbjct: 160 RFIHVSSYNAD 170


>UniRef50_A7Q1K0 Cluster: Chromosome chr7 scaffold_44, whole genome
           shotgun sequence; n=6; Magnoliophyta|Rep: Chromosome
           chr7 scaffold_44, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 399

 Score =  134 bits (324), Expect = 2e-30
 Identities = 65/147 (44%), Positives = 100/147 (68%), Gaps = 2/147 (1%)
 Frame = +3

Query: 207 KRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLG 386
           ++GTGGRSS +GIVA VFG TGF+GRYV  +L K+G+Q+++P+RG     + LK+ GDLG
Sbjct: 54  RKGTGGRSSVSGIVAVVFGATGFLGRYVVQQLAKMGSQVLVPFRGSEDSHRHLKLMGDLG 113

Query: 387 QVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE-G 563
           Q++   Y+  DE SI   +  +NVV+NL+GR+YET+N+ + +V+     ++A I +E  G
Sbjct: 114 QIVPMKYNPRDENSIKAVMAKANVVLNLIGREYETRNYSFEEVNHHMAEQLAMISKEHGG 173

Query: 564 VERFIHLSYLNAE-EHPKPLVLKKPSA 641
           + RFI +S L A    P  +++ K +A
Sbjct: 174 IMRFIQVSCLGASPSSPSRMLMAKAAA 200


>UniRef50_Q6V506 Cluster: Putative NADH:ubiquinone oxidoreductase 39
           kDa subunit; n=1; Chlamydomonas reinhardtii|Rep:
           Putative NADH:ubiquinone oxidoreductase 39 kDa subunit -
           Chlamydomonas reinhardtii
          Length = 397

 Score =  134 bits (323), Expect = 2e-30
 Identities = 78/187 (41%), Positives = 113/187 (60%), Gaps = 4/187 (2%)
 Frame = +3

Query: 81  MAAIALKTQATSKLLHLNGSMSVVYIKAANYSS-DRKPNL-AAYKRGTGGRSSFNGIVAT 254
           M  I  +  A S L  L G   + +  AA+ SS D    L  A K G GGRSS +GI AT
Sbjct: 1   MLPILGRNAAGSALARLAG---LRWAAAASQSSRDYSSTLMTADKLGPGGRSSVSGITAT 57

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTP-YHLLDEESI 431
           VFG  GF+G Y+ N+L K G+Q++ P+R    +A  LK  GDLGQ++  P   + +++ I
Sbjct: 58  VFGANGFLGSYIVNELAKRGSQVVCPFRSTENEAMHLKQMGDLGQIVLLPELDIRNDDDI 117

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEG-VERFIHLSYLNAEEH 608
            +A+  SNV+IN VG   +TKN+ + DVHVD  +R+A++  E G V+R IH S + A+E+
Sbjct: 118 KRAISRSNVIINCVGMRLQTKNWSFEDVHVDFPKRLAKLAAETGQVQRLIHFSDMGADEN 177

Query: 609 PKPLVLK 629
            K L ++
Sbjct: 178 HKSLRMR 184


>UniRef50_Q5KJ08 Cluster: NADH dehydrogenase (Ubiquinone), putative;
           n=1; Filobasidiella neoformans|Rep: NADH dehydrogenase
           (Ubiquinone), putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 411

 Score =  130 bits (313), Expect = 4e-29
 Identities = 66/144 (45%), Positives = 96/144 (66%)
 Frame = +3

Query: 168 NYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDF 347
           N S+  +P +  Y   TGGRSS +G   TVFG TGF+ RY+  KL + GTQ+I+PYR D 
Sbjct: 37  NPSASVRPAIR-YGPPTGGRSSDSGRTVTVFGSTGFLARYLIQKLARQGTQVIVPYR-DE 94

Query: 348 YDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDG 527
            + +RL+ CGDLGQ++   +     E  A+ V++++VV NLVGRDYET+N+ Y+DV+V  
Sbjct: 95  DEKRRLRPCGDLGQIVPLEWDARIPEQTAECVKHADVVYNLVGRDYETRNYSYDDVNVKV 154

Query: 528 VRRIARICREEGVERFIHLSYLNA 599
            + IA I  +  + R IH+S++NA
Sbjct: 155 AQSIAEISADMNIPRLIHVSHINA 178


>UniRef50_Q559Z0 Cluster: Putative uncharacterized protein; n=2;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 356

 Score =  126 bits (305), Expect = 3e-28
 Identities = 59/129 (45%), Positives = 87/129 (67%)
 Frame = +3

Query: 219 GGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLF 398
           G R+   G+VATVFG TGF GRY+   L + G Q+++PYR +    + LKV G+LGQ++ 
Sbjct: 32  GSRTQTTGLVATVFGATGFTGRYLVQLLARTGIQVVVPYRCEDEGFRDLKVLGELGQIIP 91

Query: 399 TPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFI 578
             + + D ESI +A+ +SN+VIN+ GRDYET+NF  +D++V    RIA +   + VE++I
Sbjct: 92  VRFDIRDSESIERAISHSNIVINMAGRDYETRNFSLDDINVHAASRIADL--SKNVEKYI 149

Query: 579 HLSYLNAEE 605
           H+S L A E
Sbjct: 150 HVSTLRASE 158


>UniRef50_Q5AJA9 Cluster: Potential mitochondrial Complex I, 40kd
           subunit; n=5; Saccharomycetales|Rep: Potential
           mitochondrial Complex I, 40kd subunit - Candida albicans
           (Yeast)
          Length = 386

 Score =  122 bits (294), Expect = 7e-27
 Identities = 66/145 (45%), Positives = 91/145 (62%)
 Frame = +3

Query: 168 NYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDF 347
           N + + K N+A    G GGRSS  G  ATVFG +GF+GRYV +KL + GT  I+P+R D 
Sbjct: 31  NITKNGKVNVAV---GAGGRSSRTGYTATVFGASGFLGRYVTSKLARHGTTTIVPFRDDM 87

Query: 348 YDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDG 527
              + LKV GDLG V F      + +SI  +V +S++VIN +G DY+TKNFK  DV++  
Sbjct: 88  -KKRFLKVTGDLGVVNFVEIDARNLQSIEDSVAHSDIVINCIGVDYDTKNFKMADVNIAL 146

Query: 528 VRRIARICREEGVERFIHLSYLNAE 602
             RIA   ++  V R+IH+S  NA+
Sbjct: 147 AERIAEATKKANVPRYIHVSSYNAD 171


>UniRef50_UPI00006CB9E4 Cluster: hypothetical protein
           TTHERM_00557760; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00557760 - Tetrahymena
           thermophila SB210
          Length = 398

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 60/166 (36%), Positives = 88/166 (53%), Gaps = 9/166 (5%)
 Frame = +3

Query: 147 VVYIKAANYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLI 326
           ++ +    +S  R   L  Y  G   R S +GI AT+FG TGF+G Y+   LG IG+ +I
Sbjct: 49  LIQVIQKQFSQQRSTQLKFYDGGN--RQSISGIRATIFGATGFMGPYIGAALGYIGSDVI 106

Query: 327 LPYRGDF-YD--AQRLKVCGDLGQ-VLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETK 494
            P+   + YD   + LK+C   GQ  +   ++  D+     A++ SNVVINLVG   + K
Sbjct: 107 FPHNHVYAYDDYVKELKLCAGSGQSYIMRHFNYDDDNMYDMAIKNSNVVINLVGSRLQNK 166

Query: 495 NFK---YNDVHVDGVRRIARIC-REEGVERFIHLSYLNAE-EHPKP 617
           NF+   Y ++HV   ++IA  C R   V R IH S   A+ + P P
Sbjct: 167 NFQKAAYANIHV--AKKIAEACARNPNVRRLIHFSAAGADTKSPSP 210


>UniRef50_A4GHP1 Cluster: NADH-ubiquinone oxidoreductase; n=2;
           Bacteria|Rep: NADH-ubiquinone oxidoreductase -
           uncultured marine bacterium EB0_39F01
          Length = 330

 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 44/128 (34%), Positives = 72/128 (56%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 425
           + T+FG +GFVGRYV  ++ K G ++ +  R    +A  +K  GD+GQV     ++ DE+
Sbjct: 7   LVTIFGGSGFVGRYVAQRMAKEGWRVRVAVRRP-NEALFVKTYGDVGQVEPILANIRDEK 65

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
           S   A+  ++ V+N VG   ET   K+ D+   G  +IA++  E GV+ F+H S + A+ 
Sbjct: 66  STRAAIIGADAVVNCVGILNETSKQKFTDLQSKGASQIAKLATECGVKTFVHFSAIGADI 125

Query: 606 HPKPLVLK 629
           +     LK
Sbjct: 126 NSHSKYLK 133


>UniRef50_Q2RYH4 Cluster: 3-beta-hydroxy-delta(5)-steroid
           dehydrogenase; n=3; Rhodospirillaceae|Rep:
           3-beta-hydroxy-delta(5)-steroid dehydrogenase -
           Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 340

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 46/122 (37%), Positives = 65/122 (53%)
 Frame = +3

Query: 240 GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 419
           G V TVFG +G +GR +   L   G ++ +  R D   A  LK  G LGQ+      + D
Sbjct: 3   GRVVTVFGGSGSIGRQLVALLADQGARVRVAVR-DTEKAHFLKPLGQLGQIAPISASVSD 61

Query: 420 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
             S+ +AV  ++ V+NLVG   E+    +  VHVDG   +AR   E GV+  IH+S L A
Sbjct: 62  AASVKRAVEGADQVVNLVGILAESGRRTFQAVHVDGAATVARASAEAGVDALIHMSALGA 121

Query: 600 EE 605
           +E
Sbjct: 122 DE 123


>UniRef50_A7HPI7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Parvibaculum lavamentivorans DS-1|Rep: NAD-dependent
           epimerase/dehydratase - Parvibaculum lavamentivorans
           DS-1
          Length = 321

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 43/118 (36%), Positives = 67/118 (56%)
 Frame = +3

Query: 252 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           TVFG +GFVGR++   L K G ++ +  R    +A  L+  G +GQV     ++ D+ S+
Sbjct: 8   TVFGGSGFVGRHIVQTLAKRGYRIRVAVRRP-NEALFLRPMGVVGQVEPIQANIRDDASV 66

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
             AV  ++ V+NLVG  +ET    ++ V  +G  R+AR   E G  R IH+S + A+E
Sbjct: 67  RAAVAGADAVVNLVGILHETGKQTFDAVQAEGAGRVARAAAEAGCGRLIHISAIGADE 124


>UniRef50_Q0BUA2 Cluster: NADH-ubiquinone oxidoreductase 39-40 kDa
           subunit-like protein; n=2; Acetobacteraceae|Rep:
           NADH-ubiquinone oxidoreductase 39-40 kDa subunit-like
           protein - Granulobacter bethesdensis (strain ATCC
           BAA-1260 / CGDNIH1)
          Length = 333

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 45/129 (34%), Positives = 72/129 (55%), Gaps = 3/129 (2%)
 Frame = +3

Query: 225 RSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTP 404
           +S+  G +ATVFG +GF+G+ +   L + G Q+ +P R D     +LK  G +GQ++   
Sbjct: 11  QSTMAGRIATVFGGSGFLGQSLIRLLAREGYQVRVPVR-DPEQVLKLKSAGSVGQIVPLG 69

Query: 405 YHLLD---EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERF 575
             L     E  IA+AV+ +++V+NLVG   E +   +  VHV     IA +  + GV  F
Sbjct: 70  VSLGSRDAEAGIARAVQGASLVVNLVGLLAEARKGDFQRVHVQAAGLIASLSAQAGVLSF 129

Query: 576 IHLSYLNAE 602
           +H+S L A+
Sbjct: 130 MHISALGAD 138


>UniRef50_Q2GE21 Cluster: NADH-ubiquinone oxidoreductase family
           protein; n=1; Neorickettsia sennetsu str. Miyayama|Rep:
           NADH-ubiquinone oxidoreductase family protein -
           Neorickettsia sennetsu (strain Miyayama)
          Length = 340

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 40/114 (35%), Positives = 63/114 (55%)
 Frame = +3

Query: 252 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           TVFG +GF+G YV  +L K G ++ +        A++LK+ G+LGQ+      +   + I
Sbjct: 34  TVFGGSGFIGSYVVRELVKSGYRVTV-VANSLSCAKKLKLSGNLGQISVVHGDIRYPDDI 92

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYL 593
            K +  S +VIN+VG   ET +  +  ++     ++A+I  E GV RFIH S L
Sbjct: 93  VKGIGNSEIVINMVGVLRETSSASFGAINHLACAQVAQIAAENGVRRFIHFSAL 146


>UniRef50_Q1GCR4 Cluster: 3-beta hydroxysteroid
           dehydrogenase/isomerase; n=17; Rhodobacterales|Rep:
           3-beta hydroxysteroid dehydrogenase/isomerase -
           Silicibacter sp. (strain TM1040)
          Length = 329

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 39/119 (32%), Positives = 67/119 (56%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 425
           + T++G +GFVGRY+  ++ K G ++ +  R    +A  +K  G  GQV     ++ D+ 
Sbjct: 4   LVTIYGGSGFVGRYIARRMAKEGWRVRVAVRRP-NEAMHVKPYGVPGQVEPVFCNIRDDA 62

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           S+A  +  ++ V+N VG   E     ++ V  +G  RIARI  + GVER +H+S + A+
Sbjct: 63  SVAAVMAGADAVVNCVGVLNEVGKNTFSAVQSEGAGRIARIAADTGVERLVHVSAIGAD 121


>UniRef50_Q3YT69 Cluster: NADH-ubiquinone oxidoreductase, putativ;
           n=8; Rickettsiales|Rep: NADH-ubiquinone oxidoreductase,
           putativ - Ehrlichia canis (strain Jake)
          Length = 320

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 36/117 (30%), Positives = 62/117 (52%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           +FG +GF+GRY+     + G  +I  +      A++LK+CG+LGQ+      + + + I 
Sbjct: 8   IFGGSGFIGRYLVKYFAENG-YIIKIFTRYPEKAKQLKLCGNLGQIEVISGDVTNVQEIE 66

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
             +   +VV+NL+G  Y TKN  + D+H      IA+  +   VE  +H S +  +E
Sbjct: 67  NNIFGCHVVVNLLGTLYSTKNSTFYDIHAKAAENIAKAAKSCDVELMVHFSAMGIDE 123


>UniRef50_Q3JEV6 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Nitrosococcus oceani ATCC 19707|Rep: NAD-dependent
           epimerase/dehydratase - Nitrosococcus oceani (strain
           ATCC 19707 / NCIMB 11848)
          Length = 308

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 36/117 (30%), Positives = 63/117 (53%)
 Frame = +3

Query: 252 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           TVFG TGF+GR + ++L + G ++ +  R      +   + G  GQ+      + DE+S+
Sbjct: 13  TVFGGTGFLGRAIVHRLVESGMRVRIVAR----HPRAPNLAGARGQIALQRADVRDEDSV 68

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           A+A++ +  V+N VG   E     +  +H +G  R+AR   E G+ R IH+S +  +
Sbjct: 69  AEALKGATGVVNAVGLYVEQGQATFRAIHEEGAERVARRAGEAGIRRLIHISGIGVD 125


>UniRef50_Q1GR77 Cluster: 3-beta hydroxysteroid
           dehydrogenase/isomerase; n=4; Sphingomonadaceae|Rep:
           3-beta hydroxysteroid dehydrogenase/isomerase -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 312

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 43/124 (34%), Positives = 64/124 (51%)
 Frame = +3

Query: 231 SFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH 410
           +F+G + TV G  GF+GRYV  +L   G ++ +  R D   A  LK  G LGQ  F    
Sbjct: 3   TFDGQLITVLGGGGFLGRYVVQRLLARGARVRIAQR-DPRAATFLKPLGGLGQTQFVHAD 61

Query: 411 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 590
           + D  S+A+AV+ S+ VINLVG   + +      V  DG   +A   +  G    +H+S 
Sbjct: 62  VRDAASVARAVQGSDAVINLVGAFDDMR-----AVQADGAGHVATTAKAAGARALVHVSA 116

Query: 591 LNAE 602
           + A+
Sbjct: 117 IGAD 120


>UniRef50_A7DMA8 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Alphaproteobacteria|Rep: NAD-dependent
           epimerase/dehydratase - Methylobacterium extorquens PA1
          Length = 389

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 40/119 (33%), Positives = 68/119 (57%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 425
           + TVFG +GF+GR+V   L K G ++ +  R     A  L+  G +GQ++    +L   +
Sbjct: 18  LVTVFGGSGFLGRHVVRALAKRGYRIRVAVRRPDL-ALFLQPLGKVGQIVGVQANLRYPD 76

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           SI +AV +S++VINLVG   E+ + +++ +  +G   IAR     G  + +H+S L A+
Sbjct: 77  SIRRAVEHSDIVINLVGILQESGSQRFSKLQTEGAGEIARAAAAVGA-KLVHVSALGAD 134


>UniRef50_A4WW99 Cluster: NADH dehydrogenase; n=5;
           Rhodobacterales|Rep: NADH dehydrogenase - Rhodobacter
           sphaeroides ATCC 17025
          Length = 328

 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 33/119 (27%), Positives = 65/119 (54%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 425
           + T++G +GFVGRY+  ++ + G ++ +  R    +A  +K  G +GQV     ++ D+ 
Sbjct: 4   LVTIYGGSGFVGRYIARRMAQQGWRVRVAVRRP-NEALFVKPYGVVGQVEPVFCNIRDDA 62

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           S+   +  ++ V+N VG   E    ++  V  +G  R+AR+   EGV+  + +S + A+
Sbjct: 63  SVRAVMHGADAVVNCVGILAEAGKNRFQSVQAEGAARVARLAAAEGVQALVQISAIGAD 121


>UniRef50_Q38CX2 Cluster: Putative uncharacterized protein; n=5;
           Trypanosomatidae|Rep: Putative uncharacterized protein -
           Trypanosoma brucei
          Length = 373

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 49/158 (31%), Positives = 79/158 (50%), Gaps = 14/158 (8%)
 Frame = +3

Query: 210 RGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYR---GDFYDAQRLKVCGD 380
           RG G  ++  G+    FG TG +G ++ +     G   I+P+R   G     + L++ GD
Sbjct: 19  RGGGSEANAMGVNVATFGATGVLGTHIHHLCCYHGFTSIVPFRFRAGMASGVRHLRMAGD 78

Query: 381 --LGQVLFTPYHLLDEESIAKAVRYS-NVVINLVGR-----DYETKN--FKYNDVHVDGV 530
             +GQ   T Y + D+E + K++    + VIN VG       YE     F    ++V+  
Sbjct: 79  GTVGQNFDTDYEI-DKEFVVKSILEKVDNVINAVGAWQEPAVYENSQSWFSMEAINVEWP 137

Query: 531 RRIARICREEGVERFIHLSYLNAEEH-PKPLVLKKPSA 641
           R +AR CRE G+ R  H+S + A+ H P  L+ +K +A
Sbjct: 138 RMLARWCREMGILRLTHMSMVGADLHSPSKLLRQKRAA 175


>UniRef50_Q4FNB8 Cluster: Probable NADH-ubiquinone oxireductase;
           n=2; Candidatus Pelagibacter ubique|Rep: Probable
           NADH-ubiquinone oxireductase - Pelagibacter ubique
          Length = 322

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 33/120 (27%), Positives = 63/120 (52%), Gaps = 1/120 (0%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           +FG +G +GR++  KL K   ++ +  R        +K   + G +     ++ DE+ I 
Sbjct: 8   IFGGSGQIGRHLIRKLTKNNYKVTVVTRNLHQKGYAIKTQANAGYIDIVEANIFDEKKIR 67

Query: 435 KAVRYSNVVINLVGRDYET-KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 611
           K    +++ INL+G  YE+ K   + ++H      ++++C+E  V++FIHLS L   + P
Sbjct: 68  KLFSQTDICINLIGILYESGKGNTFKNIHSIFPSILSKLCKEYKVQQFIHLSALGINDAP 127


>UniRef50_A0BZW4 Cluster: Chromosome undetermined scaffold_14, whole
           genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_14,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 351

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 7/155 (4%)
 Frame = +3

Query: 186 KPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDF-YD--A 356
           +P L  + +G   + + +GI AT+ G T F G Y+   LG IG++LI P+   + Y+   
Sbjct: 14  RPKLHIFDKGA--KHTPSGIRATIHGGTSFSGIYMGGMLGNIGSELIFPHNHQYNYEDHV 71

Query: 357 QRLKVCGDLGQV-LFTPYHLLDEESIAKAVRYSNVVINLVG---RDYETKNFKYNDVHVD 524
           + LK     GQ  L    +  ++E I   ++ SNVV+NL+G      + K F+ + +   
Sbjct: 72  RELKTTSGPGQNWLLHDMNYDNKEMIEWTMKNSNVVVNLLGPQKTSEKQKGFRVDQLSQC 131

Query: 525 GVRRIARICREEGVERFIHLSYLNAEEHPKPLVLK 629
              ++    +  GV R IH S   A  H + L L+
Sbjct: 132 QKEQLKHALKTPGVIRLIHFSACGANPHAESLDLQ 166


>UniRef50_Q1GZ10 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Methylobacillus flagellatus KT|Rep: NAD-dependent
           epimerase/dehydratase - Methylobacillus flagellatus
           (strain KT / ATCC 51484 / DSM 6875)
          Length = 321

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 41/130 (31%), Positives = 67/130 (51%), Gaps = 1/130 (0%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           V G +GFVG  + ++L   G  + +L  R +   ++ L +   L  V  T   + +E S+
Sbjct: 9   VVGGSGFVGSALVHRLSTAGYDVKVLTRRRE--SSKHLIL---LPNVQVTECDVFNEASL 63

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 611
           +  +   + VINL G  +E+ N  +  +HVD   RIA IC ++GV R +H+S L A    
Sbjct: 64  SGQLHGQDAVINLAGILHESGNATFESIHVDLATRIADICCKQGVPRLLHMSALKASADA 123

Query: 612 KPLVLKKPSA 641
           K   L+  +A
Sbjct: 124 KSAYLRSKAA 133


>UniRef50_Q2GII8 Cluster: NADH-ubiquinone oxidoreductase family
           protein; n=2; Anaplasma|Rep: NADH-ubiquinone
           oxidoreductase family protein - Anaplasma
           phagocytophilum (strain HZ)
          Length = 313

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
 Frame = +3

Query: 255 VFGCTGFVGRY-VCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           VFG +GF+GRY VC  + +     +  Y  +   A RLK+ G LGQV      L D   I
Sbjct: 6   VFGGSGFIGRYLVCELVAR--KYSVTVYTRNHEKAARLKLFGRLGQVDIVCGKLSDAALI 63

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
            K +   +V++NLVG   + +      +HV     IA++  + G + F+H S + A+
Sbjct: 64  QKLIADCDVIVNLVGTISDPRGAVLQYLHVTFPSNIAKLATKHG-KMFVHFSAMGAD 119


>UniRef50_Q98CD7 Cluster: NADH dehydrogenase (Ubiquinone) 1 alpha
           subcomplex; n=31; Alphaproteobacteria|Rep: NADH
           dehydrogenase (Ubiquinone) 1 alpha subcomplex -
           Rhizobium loti (Mesorhizobium loti)
          Length = 341

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 39/119 (32%), Positives = 63/119 (52%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 425
           +  VFG +GFVGR+V   L K G ++ +  R     A  L+  G++GQ+     ++    
Sbjct: 26  LVVVFGGSGFVGRHVVRALAKRGYRIRVACRRPDL-AGHLQPLGNVGQIQPVQANVRVRW 84

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           S+ +AV+ ++ V+NLV   +ET   K++ VH  G R +A   R  G     H+S L A+
Sbjct: 85  SVDRAVQGADHVVNLVAILHETGRQKFSAVHEFGSRAVAEAARSVGA-GLTHISALGAD 142


>UniRef50_Q0ACP9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Alkalilimnicola ehrlichei MLHE-1|Rep: NAD-dependent
           epimerase/dehydratase - Alkalilimnicola ehrlichei
           (strain MLHE-1)
          Length = 320

 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 35/119 (29%), Positives = 62/119 (52%), Gaps = 3/119 (2%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           + G +GF+G  +  +LG+ G ++I+P R      +R +    +  V     ++ DE+++ 
Sbjct: 8   ILGGSGFIGTTIAGRLGRDGHRVIVPTR----HRERSRHLLPVPNVEVVELNVNDEDALV 63

Query: 435 KAVRYSNVVINLVGRDYETKNFK---YNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           +A +    VINLVG   E    K   +   HV+  RR+   C+  GV R++H+S L A+
Sbjct: 64  EAFQDCTAVINLVGILNELSGPKGEGFRRAHVELPRRVISACQRAGVGRYLHMSALGAD 122


>UniRef50_A7BKW7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Beggiatoa sp. SS|Rep: NAD-dependent
           epimerase/dehydratase - Beggiatoa sp. SS
          Length = 263

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 41/125 (32%), Positives = 70/125 (56%), Gaps = 5/125 (4%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           + G TGFVG+ + N+L K+G Q+ +L  R +  + + L V   L ++L T Y   D+  +
Sbjct: 6   LLGGTGFVGKQLANRLFKMGWQVRVLTRRRE--EHRELLVLPTL-ELLSTNY---DQAQL 59

Query: 432 AKAVRYSNVVINLVG----RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
            +  R  +VVINLVG      ++ K F+    HV+  +++   C+E  ++R +H+S LNA
Sbjct: 60  NEQTRGCDVVINLVGILNESGHDGKGFQ--KAHVELPQKVIAACQENKIKRLLHISALNA 117

Query: 600 EEHPK 614
           +   K
Sbjct: 118 DATQK 122


>UniRef50_UPI0000E87D4F Cluster: NAD-dependent
           epimerase/dehydratase; n=1; Methylophilales bacterium
           HTCC2181|Rep: NAD-dependent epimerase/dehydratase -
           Methylophilales bacterium HTCC2181
          Length = 293

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 33/119 (27%), Positives = 66/119 (55%), Gaps = 1/119 (0%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPY-HLLDE 422
           V ++FG TGF+G  + ++L K   ++ L          R K+   L  +  T +  L D+
Sbjct: 3   VVSIFGGTGFIGTELIHELEKKNYEIRL--------FTRRKIPHTLNTLSKTRFIQLRDD 54

Query: 423 ESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
             ++  +  S+++I+LVG  +E K   ++DVH   ++++++I ++  ++RFIH+  L A
Sbjct: 55  TKLSNELIGSDIIIDLVGILHEQKGITFDDVHSGRLKKLSKIAQKLNIKRFIHIGALGA 113


>UniRef50_Q0F0X9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Mariprofundus ferrooxydans PV-1|Rep: NAD-dependent
           epimerase/dehydratase - Mariprofundus ferrooxydans PV-1
          Length = 317

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 35/119 (29%), Positives = 57/119 (47%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G +GFVGR +  +    G  + +  R     A+ + V G    V      ++D   I 
Sbjct: 7   VIGGSGFVGRAIAKQAVTAGHTVTVGCRHP-ERARAMLVDG----VRLKRVDVVDGRGID 61

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 611
           +A++  + VI LVG  +E   + +   HVDGV  +   C+  GV +++H+S L A   P
Sbjct: 62  EAIKGCDTVIYLVGLLFERGRYNFQAAHVDGVEHVLAACQRAGVGQYLHMSALGAGAVP 120


>UniRef50_A6FZ88 Cluster: Probable NADH-ubiquinone oxidoreductase;
           n=1; Plesiocystis pacifica SIR-1|Rep: Probable
           NADH-ubiquinone oxidoreductase - Plesiocystis pacifica
           SIR-1
          Length = 554

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 4/132 (3%)
 Frame = +3

Query: 243 IVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCG-DLGQVLFT-PYHLL 416
           +   V G +GF+GR+V + L   G ++++  RG     + L+  G +L +V F  P+   
Sbjct: 2   LTVAVAGGSGFIGRHVVDHLRAQGCRVVVLARG----LRGLEGEGVELRRVDFAGPW--- 54

Query: 417 DEESIAKAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 590
             E  A  +   + V+NLVG  R        +   HV+  + +A   R EG+ERF+H+S 
Sbjct: 55  -SEQGASLLAGCDAVVNLVGIKRAGRGSGLSFEAAHVELPKALAEAARREGIERFVHVSV 113

Query: 591 LNAEEHPKPLVL 626
             A  HP+   L
Sbjct: 114 AGARRHPRSTYL 125


>UniRef50_A5FQ11 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Dehalococcoides|Rep: NAD-dependent epimerase/dehydratase
           - Dehalococcoides sp. BAV1
          Length = 302

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 35/120 (29%), Positives = 62/120 (51%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G +GFVGR++  +L + G ++ L    +  +A R+K  G    V F    + D   + 
Sbjct: 7   VTGGSGFVGRHLLPRLAENGFKIRLLVMNET-EANRVKTPG----VEFVYGTVNDLPVLM 61

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 614
            +++    +I+LV    E KN  + +V+++G + +     E GV+RFIH+  L A   P+
Sbjct: 62  DSLKDVFAIIHLVAILRENKNATFAEVNIEGTKNMLAAATENGVKRFIHMGILGASADPR 121


>UniRef50_Q1PXS0 Cluster: Similar to dehydratase OleE [Streptomyces
           antibioticus]; n=1; Candidatus Kuenenia
           stuttgartiensis|Rep: Similar to dehydratase OleE
           [Streptomyces antibioticus] - Candidatus Kuenenia
           stuttgartiensis
          Length = 297

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
 Frame = +3

Query: 261 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 440
           G TGFVG+ + NKL +   ++    R         K+   + Q+      + D   +  A
Sbjct: 7   GSTGFVGKQLLNKLIENKYKVKCLVR----KGSEHKLGQYINQIEVVNGDITDPPCLKNA 62

Query: 441 VRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 614
           +     VIN+VG  R+   K   +  +H +G   + R  +++GV+RFI +S L A++  K
Sbjct: 63  IADCEAVINIVGIIREIPGKGVTFEKLHYEGTHNLIREAKKQGVDRFIQMSALGAKQEGK 122

Query: 615 PL 620
            L
Sbjct: 123 TL 124


>UniRef50_A6GU58 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Limnobacter sp. MED105|Rep: NAD-dependent
           epimerase/dehydratase - Limnobacter sp. MED105
          Length = 317

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 35/128 (27%), Positives = 65/128 (50%), Gaps = 7/128 (5%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G +GF+G+ VCN+L K G ++ +P R   YD  +  +     Q++    H  D  ++ 
Sbjct: 2   VIGGSGFLGQAVCNQLAKAGYRITVPTRR--YDKAKHLLTLPTCQIIEANIH--DRATLG 57

Query: 435 KAVRYSNVVINLVGRDYET------KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 596
           + V   ++V+NL+G  +        +NF+ N  HV+  + +     + G +R +H+S L 
Sbjct: 58  RLVSGQDIVVNLLGVLHSKPGKPYGQNFRVN--HVEFPKALCTAMSKHGAKRIVHVSALG 115

Query: 597 -AEEHPKP 617
              ++P P
Sbjct: 116 VGVQNPAP 123


>UniRef50_A5P8M1 Cluster: NADH ubiquinone oxidoreductase, putative;
           n=3; Erythrobacter|Rep: NADH ubiquinone oxidoreductase,
           putative - Erythrobacter sp. SD-21
          Length = 344

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 2/126 (1%)
 Frame = +3

Query: 231 SFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH 410
           + NG    + G TGF+G YV   L   G +L +  R     A +LK   +LGQ+ F    
Sbjct: 34  ALNGKTVALMGGTGFLGNYVAQALLSRGARLRICGRNP-QAAFKLKPLANLGQLQFARMD 92

Query: 411 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRR--IARICREEGVERFIHL 584
             D  S+ + ++ ++ V+NLVG      +F  +   + G     +A   ++ G   F+H+
Sbjct: 93  ATDRRSVEQCIKGADAVVNLVG------SFDGDLARLMGEAPGWMAEAAKKTGAMSFVHV 146

Query: 585 SYLNAE 602
           S + AE
Sbjct: 147 SAIAAE 152


>UniRef50_Q6G583 Cluster: NADH-ubiquinone oxidoreductase; n=3;
           Bartonella|Rep: NADH-ubiquinone oxidoreductase -
           Bartonella henselae (Rochalimaea henselae)
          Length = 334

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 31/119 (26%), Positives = 59/119 (49%)
 Frame = +3

Query: 252 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           TVFG +GFVGR+V   L K G ++ +  R        L++ G++GQ       +    S+
Sbjct: 17  TVFGGSGFVGRHVVEALTKRGYRVRIAVRSPQKAYYMLQI-GEVGQTQMLRTDIKCRASV 75

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 608
           A+A+  S+  + L G   +     +    ++G + ++ +  E G+   I++S L A ++
Sbjct: 76  ARALLGSDGAVFLPGSLAQANQPNFQKTQIEGAQNVSELTAEAGIP-LIYMSALVANKN 133


>UniRef50_Q3JE30 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Chromatiales|Rep: NAD-dependent epimerase/dehydratase -
           Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 320

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 33/118 (27%), Positives = 57/118 (48%), Gaps = 2/118 (1%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           + G TGFVGR++ + L + G ++ +  R      QR +    L  +      + D   +A
Sbjct: 8   ILGGTGFVGRWLSSHLVEQGYKVRVLTR----HWQRHRDLLVLPGLRLMETDVYDPAQLA 63

Query: 435 KAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
                   VINL+G   +       +  VH D   ++A+IC + G++R +H+S LNA+
Sbjct: 64  AQFNGCQSVINLIGILNEKGRNGHGFRQVHADLPEKVAQICLDTGIKRLLHMSALNAD 121


>UniRef50_Q125I6 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Comamonadaceae|Rep: NAD-dependent epimerase/dehydratase
           - Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 318

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 32/115 (27%), Positives = 56/115 (48%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           + G TGFVGR+VC KL ++  ++ +  R    +A+ L+    L  V+    H  D  ++ 
Sbjct: 6   ILGGTGFVGRHVCEKLAQLQCRVTVATR-RLDNARHLQTLPML-DVIEIDVH--DSAALT 61

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
             +   + V+NL+   + T+   +   HV     + R C   G+ R +H+S L A
Sbjct: 62  SLLAGHDAVVNLIAILHGTE-AAFEKAHVQLPLALVRACEAAGLRRIVHISALGA 115


>UniRef50_Q5FPV9 Cluster: Putative oxidoreductase; n=1;
           Gluconobacter oxydans|Rep: Putative oxidoreductase -
           Gluconobacter oxydans (Gluconobacter suboxydans)
          Length = 340

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 36/120 (30%), Positives = 56/120 (46%)
 Frame = +3

Query: 240 GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 419
           G V  V G  GFVGR +  +L   G  + +       D    +  GD G+V F    + D
Sbjct: 32  GRVVAVLGGGGFVGRELVGRLVASGHVVRVGSGNPEADQALARFPGD-GRVEFIKASVND 90

Query: 420 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
            +S+      ++  INLV          +  V+V+G R  A + R EGVE+++H+S + A
Sbjct: 91  ADSLEHLFSGADAGINLVSIMSPDVKAMHR-VNVEGARLAALVARREGVEQYLHMSAIGA 149


>UniRef50_Q2Y682 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Nitrosospira multiformis ATCC 25196|Rep: NAD-dependent
           epimerase/dehydratase - Nitrosospira multiformis (strain
           ATCC 25196 / NCIMB 11849)
          Length = 312

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/115 (26%), Positives = 56/115 (48%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           +FG +GFVG+++ N L      L +P R    + +R K   ++         + D+  + 
Sbjct: 8   IFGGSGFVGKHLANLLTNREIYLRIPTR----NYERAKELLEIPTTDLIEADIYDDRDLD 63

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
           + +   + VINLVG         ++ VHV+  ++I   C+  G+ R +H+S L A
Sbjct: 64  RLLLGIDAVINLVG----VLQGDFHAVHVELPQKIIAACKRNGITRILHMSALKA 114


>UniRef50_Q1YEV9 Cluster: NADH-ubiquinone oxidoreductase; n=7;
           Alphaproteobacteria|Rep: NADH-ubiquinone oxidoreductase
           - Aurantimonas sp. SI85-9A1
          Length = 369

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 33/118 (27%), Positives = 61/118 (51%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           VFG +GFVGRY+   L + G ++ +  R     A  L+  G++GQ++    +L    S+ 
Sbjct: 46  VFGGSGFVGRYLVQALARRGHRIRVACRRPDL-AYHLQPNGNMGQIMPIQANLRYPWSVE 104

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 608
           +AV  ++ V+NLVG   ++    ++ +   G R +A    + G      +S + A+E+
Sbjct: 105 RAVEGADHVVNLVGILAQSGQQSFDALQSFGARTVAEATAKIGA-GMTQISAIGADEN 161


>UniRef50_A1VGT7 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Desulfovibrio vulgaris subsp. vulgaris|Rep:
           NAD-dependent epimerase/dehydratase - Desulfovibrio
           vulgaris subsp. vulgaris (strain DP4)
          Length = 304

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
 Frame = +3

Query: 252 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           T+FG  GF+G +VC+KL + G  + +    D   +  L+      Q + T  ++LDEE +
Sbjct: 4   TLFGGAGFLGSHVCDKLSEAGHDVTVV---DLRPSPYLRP----DQTMITG-NILDEELV 55

Query: 432 AKAVRYSNVVINLVG-RDYETKNFKYND---VHVDGVRRIARICREEGVERFIHLSYL 593
           A+AV  +++V N  G  D    N +  D   ++V G       CR+ GV+R++  S L
Sbjct: 56  ARAVEGADMVFNYAGIADIGEANRRPVDTARINVLGNVIALEACRKAGVKRYVFASSL 113


>UniRef50_UPI0000F21730 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 392

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 19/36 (52%), Positives = 27/36 (75%)
 Frame = +3

Query: 495 NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           N+KY DV V    +IAR  RE G+++FIH+S+LNA+
Sbjct: 302 NYKYEDVFVSIPLQIARATREAGIKKFIHMSHLNAD 337


>UniRef50_Q39C42 Cluster: NAD-dependent epimerase/dehydratase; n=30;
           Burkholderiales|Rep: NAD-dependent epimerase/dehydratase
           - Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 319

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 4/122 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           + G TGF+G  + N L + G Q+ +  R   + A+ L++      V       LD  ++A
Sbjct: 8   LLGGTGFIGSRLVNALIESGKQVRIGTRRRDH-ARHLQML----PVEVVELEALDTRTLA 62

Query: 435 KAVRYSNVVINLVGRDYETKNFKYND----VHVDGVRRIARICREEGVERFIHLSYLNAE 602
           + V  ++  INLVG  +  +   Y       HV     +A  C E GV R +H+S L A+
Sbjct: 63  RFVAGAHAAINLVGVLHGGRGTPYGPGFERAHVTLPAALATACTEVGVRRVLHMSALGAD 122

Query: 603 EH 608
            H
Sbjct: 123 SH 124


>UniRef50_A1WZI3 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Halorhodospira halophila SL1|Rep: NAD-dependent
           epimerase/dehydratase - Halorhodospira halophila (strain
           DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM
           244 / SL1))
          Length = 320

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 38/122 (31%), Positives = 53/122 (43%), Gaps = 3/122 (2%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TGFVG +V N+L   G ++    R        L   G   ++     H  DE  + 
Sbjct: 8   VVGGTGFVGMHVANRLADRGYRIRALTRRSHRGRDLLLFPGL--RLFEADVH--DERELV 63

Query: 435 KAVRYSNVVINLVGRDYET---KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
           +     + VINL G        +   Y++VHVD  RR+    R   V R +H+S L A  
Sbjct: 64  RHFSGCHAVINLAGAHTGRGGPREDAYHEVHVDLPRRVLAAARRASVPRLVHMSALGA-- 121

Query: 606 HP 611
           HP
Sbjct: 122 HP 123


>UniRef50_Q4UMY6 Cluster: Putative oxidoreductase protein; n=15;
           Rickettsia|Rep: Putative oxidoreductase protein -
           Rickettsia felis (Rickettsia azadi)
          Length = 431

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 1/118 (0%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHL-LDEESI 431
           + G  GF+G Y+  +L K   ++I   R    D +  K      +V++  +++ L  +S 
Sbjct: 5   ITGANGFIGSYITAELLKNNYEVICCVR----DVESTKKKFPTAEVIYCDFNIDLTPQSW 60

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
              +   ++VIN+ G    +      +VHV+G + + + C    V+R IH+S L  ++
Sbjct: 61  INRLNNIDIVINVSGVLASSHANNIENVHVNGPKALFKACTLTNVKRIIHISALGIDD 118


>UniRef50_Q31J38 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Thiomicrospira crunogena XCL-2|Rep: NAD-dependent
           epimerase/dehydratase - Thiomicrospira crunogena (strain
           XCL-2)
          Length = 323

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 36/123 (29%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
 Frame = +3

Query: 240 GIVATVFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLL 416
           G    V G TGF+GR V N+L K G ++ ++  R + +    L     L Q+      LL
Sbjct: 3   GNKVVVLGGTGFIGRSVVNELSKSGYEISVVVRRPERFRDYMLYKNTKLVQI----DSLL 58

Query: 417 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGV-RRIARICREEGVERFIHLSYL 593
           D E + KA   ++VV+NL   D   K    ++  +  V ++I +     G++R + LS +
Sbjct: 59  DSEGLKKAFMGTDVVVNLTA-DLTAKTEAVSEKDIVAVNQQIKKAVESAGIKRVVALSQI 117

Query: 594 NAE 602
            A+
Sbjct: 118 GAD 120


>UniRef50_Q2S702 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerase; n=1; Hahella chejuensis KCTC 2396|Rep:
           Predicted nucleoside-diphosphate-sugar epimerase -
           Hahella chejuensis (strain KCTC 2396)
          Length = 436

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 30/115 (26%), Positives = 50/115 (43%)
 Frame = +3

Query: 261 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 440
           G  GF+   V  KL + G Q++   R        + V   +  +     HL   E  +  
Sbjct: 7   GAGGFIASVVLEKLLEQGCQVVAVARR----RANIPVSDSVTFIQADLQHLTRMEDWSPM 62

Query: 441 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
           +R  + VIN  G   E++   ++ VH    + +   C + GVERF+ +S L  E+
Sbjct: 63  LRGVDAVINCAGILRESRKGDFDLVHFQAPKALVEACLQNGVERFVQISALGTEQ 117


>UniRef50_Q8KDL0 Cluster: 3-beta hydroxysteroid
           dehydrogenase/isomerase family protein; n=10;
           Chlorobiaceae|Rep: 3-beta hydroxysteroid
           dehydrogenase/isomerase family protein - Chlorobium
           tepidum
          Length = 331

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 2/117 (1%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TGF+G  + ++L   G  + +  R    D   LK C  L ++      + D  S++
Sbjct: 7   VTGGTGFIGSRLVHRLAASGEDVYVLVRASS-DLASLKEC--LDRITLVYGDVTDIASLS 63

Query: 435 KAVRYSNVVINLVGRDY--ETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
            A   +  V +  G  Y  + KN     ++V+G + +   CR   V+R +H+S + A
Sbjct: 64  GAFEGAEEVYHCAGITYMGDRKNPLLQRINVEGTQNVLDACRRAKVKRVVHVSSITA 120


>UniRef50_Q67KJ4 Cluster: Putative oxidoreductase; n=1;
           Symbiobacterium thermophilum|Rep: Putative
           oxidoreductase - Symbiobacterium thermophilum
          Length = 342

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 2/117 (1%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVL-FTPYHLLDEESI 431
           V G TGF+G  +   L + G Q+ +  R      +   V G L   L      L DE S+
Sbjct: 4   VTGATGFIGSQLVPHLVEQGRQVRILVRSR---QKAEAVFGPLCAALEVAEGDLGDEASL 60

Query: 432 AKAVRYSNVVINLVGR-DYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
           A+A    + V +L  R +++    +   ++V+G RR+   C   GV+R +H+S + A
Sbjct: 61  ARAAAGVDRVYHLASRINFQGSLRRMRAINVEGTRRLLDACAAAGVKRVVHMSSIAA 117


>UniRef50_A3ES38 Cluster: Putative nucleoside-diphosphate-sugar
           epimerase; n=1; Leptospirillum sp. Group II UBA|Rep:
           Putative nucleoside-diphosphate-sugar epimerase -
           Leptospirillum sp. Group II UBA
          Length = 299

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 22/66 (33%), Positives = 35/66 (53%)
 Frame = +3

Query: 402 PYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIH 581
           P ++ D  S+A      ++V++L G   ETK+  Y  +HVDG R +    +   V R I+
Sbjct: 49  PGNVTDRGSLAPVFDGVDMVLHLTGILAETKSQSYEAIHVDGTRNVLDASKAGRVSRIIY 108

Query: 582 LSYLNA 599
           LS + A
Sbjct: 109 LSAIGA 114


>UniRef50_Q9HNV3 Cluster: NADH dehydrogenase/oxidoreductase-like
           protein; n=5; Halobacteriaceae|Rep: NADH
           dehydrogenase/oxidoreductase-like protein -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 303

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 4/120 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TGF+G ++C +L   G  +    R     A    V   +G V         +E++A
Sbjct: 13  VTGGTGFIGTHLCRELDDRGHDVTAFAREPADAALPADVTRIVGDVTV-------KETVA 65

Query: 435 KAVRYSNVVINLVGRDYETK----NFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
            A+   + V+NLV      K    + ++ DVH+ G   +     E GVE  + LS L+A+
Sbjct: 66  NAIDGHDAVVNLVALSPLFKPSGGDSRHLDVHLGGTENVVAAASEAGVEYILQLSALDAD 125


>UniRef50_A3YG10 Cluster: Putative uncharacterized protein; n=1;
           Marinomonas sp. MED121|Rep: Putative uncharacterized
           protein - Marinomonas sp. MED121
          Length = 306

 Score = 39.9 bits (89), Expect = 0.051
 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
 Frame = +3

Query: 261 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCG-DLGQVLFTPYHLLDEESIAK 437
           G TG++GRY+  +L K     I   R      ++L+  G +  Q+      + D  S+A 
Sbjct: 9   GATGYLGRYLVQRLLKQNGPFIAMGRS----IKKLESMGLETQQIRLA--QVTDPISLAG 62

Query: 438 AVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH 608
                +VVI+ VG   +     Y DV       +       GV++FI++S  NA  H
Sbjct: 63  CCHGIDVVISCVGITRQKDGLNYMDVDYQANINLLEEAERSGVKKFIYISAFNAPNH 119


>UniRef50_A4T0E5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Polynucleobacter sp. QLW-P1DMWA-1|Rep: NAD-dependent
           epimerase/dehydratase - Polynucleobacter sp.
           QLW-P1DMWA-1
          Length = 302

 Score = 39.5 bits (88), Expect = 0.068
 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 5/120 (4%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDE-ESI 431
           + G  GFVGR +  +L   G  +++P        + L++   +  +     H  DE +++
Sbjct: 7   LIGGNGFVGRVIAAQLQAAGYSVLIP-TSHVVAGRELRLLPKV-HLEDADVHDFDELQNL 64

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDV----HVDGVRRIARICREEGVERFIHLSYLNA 599
              ++    VINLVG  ++ +   Y  V    HVD  + I    +  G++R++H+S L A
Sbjct: 65  CGRIQLRGAVINLVGVLHDKEAQPYGKVFKAAHVDLPKNIITAMQLHGLKRYLHMSALGA 124


>UniRef50_Q2W604 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerase; n=1; Magnetospirillum magneticum AMB-1|Rep:
           Predicted nucleoside-diphosphate-sugar epimerase -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 343

 Score = 39.1 bits (87), Expect = 0.090
 Identities = 22/63 (34%), Positives = 28/63 (44%)
 Frame = +3

Query: 420 EESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
           E  +A  +   +VV+N  G      +     VH  G  R+ R C   GV R IHLS L A
Sbjct: 43  EAVLAAHLTGHDVVVNAAGLVRGRGSNTMAAVHAQGTERLVRACLAAGVSRLIHLSALGA 102

Query: 600 EEH 608
             H
Sbjct: 103 SSH 105


>UniRef50_Q1LGK6 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Ralstonia metallidurans CH34|Rep: NAD-dependent
           epimerase/dehydratase - Ralstonia metallidurans (strain
           CH34 / ATCC 43123 / DSM 2839)
          Length = 430

 Score = 39.1 bits (87), Expect = 0.090
 Identities = 38/129 (29%), Positives = 53/129 (41%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G +G +G  +C +L   G ++I   RG         V  D G    T   +   E   
Sbjct: 11  VCGASGLIGAVLCKRLEAQGHEVI---RGVRTPTSARDVAMDFG----TDTTI---EQWL 60

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPK 614
             V+  +VVIN VG   ET   ++  VH      + R C + GV R I +S L A+    
Sbjct: 61  PRVQGMHVVINAVGIIVETGTNRFEAVHHLAPAALFRACAKAGVGRVIQISALGADRGDT 120

Query: 615 PLVLKKPSA 641
           P    K  A
Sbjct: 121 PYFRSKRGA 129


>UniRef50_Q11Z70 Cluster: Nucleoside-diphosphate-sugar epimerase;
           n=1; Cytophaga hutchinsonii ATCC 33406|Rep:
           Nucleoside-diphosphate-sugar epimerase - Cytophaga
           hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 322

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G  G VG ++CN+L   G ++    R +  D   LK     G +      + D  S+ 
Sbjct: 4   VTGANGLVGSFLCNELAGKGYRVKALVR-EKSDTSLLKAVA--GSIELVYGDITDAGSLV 60

Query: 435 KAVRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
            A+     V++       +  KN +    +V G R +  +  E+GV++ IH+S + A
Sbjct: 61  DAMEDVMCVVHTAAVISFWNKKNKEMYQTNVVGTRNVVDVALEKGVKKMIHISSIAA 117


>UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5;
           Halobacteriaceae|Rep: UDP-glucose 4-epimerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 334

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 37/136 (27%), Positives = 59/136 (43%), Gaps = 14/136 (10%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLI-LPYRGDFYDAQRLKVCGDLGQVL---------FTP 404
           V G  GF+G ++  +    G  ++ L  R  FYD    +   D GQ           F  
Sbjct: 11  VTGGAGFIGGHLAQRFAADGHDVVVLDNRDPFYDLDIKQHNVDAGQEAARNSDGSYEFIE 70

Query: 405 YHLLDEESIAKAVRYSNVVINLV---GRDYETKN-FKYNDVHVDGVRRIARICREEGVER 572
             + D E +   V  ++ V +     G     KN  KY++V+V+G   +   CR+EG+ER
Sbjct: 71  GDVRDAELVTDLVADADYVYHQAAQAGVRPSVKNPRKYDEVNVNGTLNLLDACRDEGIER 130

Query: 573 FIHLSYLNAEEHPKPL 620
           F+  S  +    P+ L
Sbjct: 131 FVMASSSSVYGKPQYL 146


>UniRef50_Q7NWF7 Cluster: Probable NADH-ubiquinone oxidoreductase;
           n=1; Chromobacterium violaceum|Rep: Probable
           NADH-ubiquinone oxidoreductase - Chromobacterium
           violaceum
          Length = 313

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 27/117 (23%), Positives = 55/117 (47%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           + G +GF+GR++  +L   G ++ +  R       R+    +L   +    H  D   +A
Sbjct: 8   LIGGSGFIGRHLAAQLASRGHRITIASRRTGLPDFRVLPSAEL---VSADIH--DPGQLA 62

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
             +   + V+++VG  + ++  ++   H     +I   CR +GV R +H+S L A +
Sbjct: 63  GLIAGHDAVVSMVGILHGSRA-QFEKAHAQLPEKIVDACRRQGVRRLVHVSALGAAQ 118


>UniRef50_Q746J9 Cluster: NADH-ubiquinone oxidoreductase 39 kDa
           subunit/NADH dehydrogenase; n=2; Thermus
           thermophilus|Rep: NADH-ubiquinone oxidoreductase 39 kDa
           subunit/NADH dehydrogenase - Thermus thermophilus
           (strain HB27 / ATCC BAA-163 / DSM 7039)
          Length = 287

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 39/116 (33%), Positives = 52/116 (44%), Gaps = 1/116 (0%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIG-TQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           V G TGFVGR V   L   G T L+L  R        + V GD+ +       + D E  
Sbjct: 5   VVGGTGFVGREVVRLLLARGHTPLVLARRSRPLPEGAVLVEGDIAR------EVPDLEG- 57

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
           A+A  Y   +I   G+ +         VHV+GVR + R     GV R +H+S L A
Sbjct: 58  AEAAIYLAGIIRERGQTFRA-------VHVEGVRNLLRAMERAGVGRLLHMSALGA 106


>UniRef50_Q5NR25 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerase; n=1; Zymomonas mobilis|Rep: Predicted
           nucleoside-diphosphate-sugar epimerase - Zymomonas
           mobilis
          Length = 307

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 19/65 (29%), Positives = 33/65 (50%)
 Frame = +3

Query: 411 LLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSY 590
           L DE+S+ K V     VI++ G         +  +++ G  ++    +  G++RFIH+S 
Sbjct: 48  LEDEDSLKKLVSSCQAVIHMAGAVKAENREAFAHINLTGTEKLLAATKAAGIKRFIHVSS 107

Query: 591 LNAEE 605
           L A E
Sbjct: 108 LAARE 112


>UniRef50_UPI00015BC9D3 Cluster: UPI00015BC9D3 related cluster; n=1;
           unknown|Rep: UPI00015BC9D3 UniRef100 entry - unknown
          Length = 303

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 38/121 (31%), Positives = 54/121 (44%), Gaps = 4/121 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TGFVG+YV   L K      L          R KV      V F      DEES+ 
Sbjct: 5   VAGGTGFVGKYVVEALEKSTHSYKL--------LTRKKVSKPHIVVDF-----FDEESLK 51

Query: 435 KAVRYS--NVVINLVGRDYE--TKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           KA      +V+INL+G   E  +K   + ++H    + +  + +E G++  IH+S L   
Sbjct: 52  KAFEQEKPDVLINLIGILVEEPSKGITFENIHYLIPKNLYTVAKEYGIKHIIHMSALGVS 111

Query: 603 E 605
           E
Sbjct: 112 E 112


>UniRef50_Q9X9X6 Cluster: Putative uncharacterized protein SCO1896;
           n=2; Streptomyces|Rep: Putative uncharacterized protein
           SCO1896 - Streptomyces coelicolor
          Length = 269

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 1/106 (0%)
 Frame = +3

Query: 303 GKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRD 482
           G +GT +     G  Y+ + L +    G+       L D +++ +AVR  + +I+L G  
Sbjct: 14  GGLGTLMRELLPGHGYELRLLDLLPVEGEPDAIVADLADRDALREAVRGVDAIIHLAGIS 73

Query: 483 YETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEH-PKP 617
            E    K    +++G   +    REEGV R +  S  +A  + P+P
Sbjct: 74  LEASFDKILAANIEGTYNLYEAAREEGVGRIVFASSNHAVGYTPRP 119


>UniRef50_A7H9M3 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=4; Cystobacterineae|Rep: NAD-dependent
           epimerase/dehydratase precursor - Anaeromyxobacter sp.
           Fw109-5
          Length = 347

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TGF+G  +   L   G +L L  R     A+RL       +V+     L DE ++ 
Sbjct: 5   VTGATGFLGATLVPLLAAEGHRLRLLQRSAAPGAERLGA-----EVVRAS--LADEGAVR 57

Query: 435 KAVRYSNVVINLVGR-DYETKNFK-YNDVHVDGVRRIARICREEGVERFI 578
           +AVR  + V +L G+ D++    +   ++HV G RR+   C   G +R +
Sbjct: 58  EAVRGVDAVYHLAGQVDFDPAEPRALYELHVQGTRRLLEACVAAGTKRVV 107


>UniRef50_A6G7N0 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Oxidoreductase, short
           chain dehydrogenase/reductase family protein -
           Plesiocystis pacifica SIR-1
          Length = 373

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 11/131 (8%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVL--FTPYHLLDE-E 425
           V G +GF+G ++C  L + G  +    R     A+      + G+V+     Y  LD+ +
Sbjct: 3   VTGASGFIGSHLCQVLRERGHAVQAMVRKTSKLAKLEDAAREGGRVIPFELAYASLDDVD 62

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRI------ARICREEGVERFIHLS 587
           ++ +AVR   VV N+ G         ++  +V GV  +      AR    +G  R +H+S
Sbjct: 63  ALTEAVRGVEVVYNIAGTTAAFDRVGFDRTNVAGVDNLIAAIERARASEGKGPRRLVHVS 122

Query: 588 YLNA--EEHPK 614
            L A    HPK
Sbjct: 123 SLMAAGPSHPK 133


>UniRef50_A0L6A2 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Magnetococcus sp. MC-1|Rep: NAD-dependent
           epimerase/dehydratase - Magnetococcus sp. (strain MC-1)
          Length = 294

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 17/56 (30%), Positives = 32/56 (57%)
 Frame = +3

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYL 593
           S+  A+     VI+LVG   E ++  + ++H  G   + +  ++ GV+RF+H+S L
Sbjct: 54  SLQTAMEGVTCVIHLVGILAEQRHRSFEEIHHQGTLNVLQAAKQAGVKRFLHMSSL 109


>UniRef50_Q3SGD6 Cluster: Nucleoside-diphosphate-sugar epimerases;
           n=1; Thiobacillus denitrificans ATCC 25259|Rep:
           Nucleoside-diphosphate-sugar epimerases - Thiobacillus
           denitrificans (strain ATCC 25259)
          Length = 345

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 36/131 (27%), Positives = 63/131 (48%), Gaps = 11/131 (8%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           V G +GFVG ++ ++L   G  + +L  R +   A+ L +   + +V+    H  DE  +
Sbjct: 8   VLGGSGFVGTHLVSQLAARGLNVRVLSRRRE--TAKELILLPTV-EVVEADVH--DEHEL 62

Query: 432 AKAVRYSNVVINLVGRDYETKNFK----------YNDVHVDGVRRIARICREEGVERFIH 581
            +  R  + VINLVG  +E K  +          +  VH++  R+I     E  V R +H
Sbjct: 63  VRHFRGMDAVINLVGILHEGKVGRADLPSARRGDFQRVHIELPRKIVHAMGEANVHRLLH 122

Query: 582 LSYLNAEEHPK 614
           +S L A+ + +
Sbjct: 123 MSALGADPNSR 133


>UniRef50_Q1K3T7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep: NAD-dependent
           epimerase/dehydratase - Desulfuromonas acetoxidans DSM
           684
          Length = 297

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 2/111 (1%)
 Frame = +3

Query: 261 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 440
           G TGFVG +V   L   G  +    R      +       L QV      + +   + +A
Sbjct: 7   GATGFVGHHVIQALLLNGHTVRCLVR------KPTPSLTSLVQVETVQGDITNPAELKQA 60

Query: 441 VRYSNVVINLVG--RDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLS 587
           +   + +I+LVG  R +  +   +  +HV+  R I     E G++R++H+S
Sbjct: 61  MSDCDAIIHLVGIIRAFPQRGITFEKLHVEATRNIITAAAEAGIDRYLHMS 111


>UniRef50_A3WA10 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerase; n=4; Sphingomonadales|Rep: Predicted
           nucleoside-diphosphate-sugar epimerase - Erythrobacter
           sp. NAP1
          Length = 304

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 28/120 (23%), Positives = 52/120 (43%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 425
           +  + G TGFVG+   +   + G  +    R D    +R         V + P  L   E
Sbjct: 3   IVAITGATGFVGKATLDVAVQKGLHVRALTRRDAQPRER---------VTWVPGTLDRAE 53

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
           ++ + V   + VI++ G        ++   +V G   +    + +G+ERF+ +S L+A E
Sbjct: 54  ALEELVSGCDAVIHVAGLTSTPNPGRFEAANVTGTANMIAAAKSQGIERFVFVSSLSARE 113


>UniRef50_Q5P3S8 Cluster: Predicted nucleoside-diphosphate-sugar
           epimerases; n=4; Betaproteobacteria|Rep: Predicted
           nucleoside-diphosphate-sugar epimerases - Azoarcus sp.
           (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 321

 Score = 36.7 bits (81), Expect = 0.48
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           + G +GF+G  V N+L     ++++P R     A R +    L  V      + D  ++A
Sbjct: 8   LIGGSGFLGSAVANQLAGAAVEVVVPTRR----ASRARHLLLLPTVDVVEADVHDPATLA 63

Query: 435 KAVRYSNVVINLVGRDYETKNFKYND----VHVDGVRRIARICREEGVERFIHLSYLNA 599
             V   + VINLVG  +      Y       HV+  ++I   C    V   +H+S L A
Sbjct: 64  HLVSGVDAVINLVGILHSRSGSPYGRDFARAHVELPQKIVAACHAARVPHLVHVSALGA 122


>UniRef50_Q9HCX3 Cluster: Zinc finger protein 304; n=4; Homo
           sapiens|Rep: Zinc finger protein 304 - Homo sapiens
           (Human)
          Length = 659

 Score = 36.7 bits (81), Expect = 0.48
 Identities = 27/91 (29%), Positives = 43/91 (47%)
 Frame = +3

Query: 333 YRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKAVRYSNVVINLVGRDYETKNFKYND 512
           ++GD YD Q L  CGD G+     + LLD +     VR    +    G  ++ K+   N 
Sbjct: 213 HQGD-YDGQMLFSCGDEGKAFLDTFTLLDSQMTHAEVRPFRCL--PCGNVFKEKSALINH 269

Query: 513 VHVDGVRRIARICREEGVERFIHLSYLNAEE 605
             +     I+ +C+E G + FIHL +L   +
Sbjct: 270 RKIHS-GEISHVCKECG-KAFIHLHHLKMHQ 298


>UniRef50_Q2FQM3 Cluster: Putative uncharacterized protein
           precursor; n=1; Methanospirillum hungatei JF-1|Rep:
           Putative uncharacterized protein precursor -
           Methanospirillum hungatei (strain JF-1 / DSM 864)
          Length = 345

 Score = 36.3 bits (80), Expect = 0.63
 Identities = 18/43 (41%), Positives = 22/43 (51%)
 Frame = +3

Query: 483 YETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 611
           Y   N K  D+  D  R I RI REEG    I + ++NAE  P
Sbjct: 161 YWNGNQKGQDLFKDAYRHIIRIMREEGASNLIWIYHVNAESQP 203


>UniRef50_Q73MR8 Cluster: Epimerase/dehydratase, putative; n=2;
           Bacteria|Rep: Epimerase/dehydratase, putative -
           Treponema denticola
          Length = 329

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 4/61 (6%)
 Frame = +3

Query: 417 DEESIAKAVRYS-NVVINLVGR---DYETKNFKYNDVHVDGVRRIARICREEGVERFIHL 584
           D +S+ K +  S + VINL      D E K+  Y++V+VDG   + ++C E G+++ I  
Sbjct: 49  DIDSLKKELSSSLDCVINLAAEHRDDVEPKSL-YDEVNVDGAENVCKVCSELGIKKIIFT 107

Query: 585 S 587
           S
Sbjct: 108 S 108


>UniRef50_A0QDT4 Cluster: Putative uncharacterized protein; n=1;
           Mycobacterium avium 104|Rep: Putative uncharacterized
           protein - Mycobacterium avium (strain 104)
          Length = 214

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 34/112 (30%), Positives = 52/112 (46%)
 Frame = +3

Query: 252 TVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           TVFG TG +GR+V   L   G       R    +  +L+V      +      L D E++
Sbjct: 6   TVFGATGQIGRFVVADLLADGHAATAYVR----NPGKLQVADP--HLTVATGELSDAEAV 59

Query: 432 AKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLS 587
            KAVR ++ VI+ +G    ++  K   V  +G R I    + E V R+I L+
Sbjct: 60  RKAVRGADAVISALGPSL-SRRAKGTPV-TEGTRNIVAAMQAEHVSRYIGLA 109


>UniRef50_Q0ANG5 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=1; Maricaulis maris MCS10|Rep:
           NAD-dependent epimerase/dehydratase precursor -
           Maricaulis maris (strain MCS10)
          Length = 431

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 17/50 (34%), Positives = 26/50 (52%)
 Frame = +3

Query: 453 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           +VVIN VG   +        VHVDG   + + C + GV R +H+S +  +
Sbjct: 67  DVVINCVGVLQDGLGDSSRKVHVDGAMALFKACEQAGVGRVLHISAVGVD 116


>UniRef50_Q12VM5 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           cellular organisms|Rep: NAD-dependent
           epimerase/dehydratase - Methanococcoides burtonii
           (strain DSM 6242)
          Length = 294

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 4/115 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           VFG  GF+G Y+  +L       +  Y     D    K    + + +F   ++LD+  +A
Sbjct: 7   VFGGCGFLGSYLVERL------CMKKYEVTVADLNLSKY---INKDIFVECNILDKIKVA 57

Query: 435 KAVRYSNVVINLVGRDYETKNFKYN----DVHVDGVRRIARICREEGVERFIHLS 587
           + V+ +++V N  G     K  +      +++V G   I   C + GVERF++ S
Sbjct: 58  ELVKNADIVYNFAGMANLDKAVEDPCGTIELNVIGNLNILDACMQSGVERFVYAS 112


>UniRef50_Q9A4D7 Cluster: Putative uncharacterized protein; n=1;
           Caulobacter vibrioides|Rep: Putative uncharacterized
           protein - Caulobacter crescentus (Caulobacter
           vibrioides)
          Length = 430

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 18/48 (37%), Positives = 26/48 (54%)
 Frame = +3

Query: 459 VINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           V+N  G   ++     N VHV+GVRR+A+ C E    R +H+S    E
Sbjct: 69  VVNCAGALQDSPRDDLNAVHVEGVRRLAQAC-EAKRARLVHISAAGVE 115


>UniRef50_Q0C1U1 Cluster: Putative UDP-glucose 4-epimerase; n=1;
           Hyphomonas neptunium ATCC 15444|Rep: Putative
           UDP-glucose 4-epimerase - Hyphomonas neptunium (strain
           ATCC 15444)
          Length = 330

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 29/113 (25%), Positives = 51/113 (45%)
 Frame = +3

Query: 261 GCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAKA 440
           G TGFVGR    +L +  TQ  +P R      Q  +   D   + +    L  + +++  
Sbjct: 11  GATGFVGR----QLLRDRTQNSVPVRA-LARMQPHRKLTDGNGIEWISGDLSSDAALSSL 65

Query: 441 VRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
           V  +++VI+L G         + +V+      + R  +  GV+ F+H+S L A
Sbjct: 66  VSNADIVIHLAGATKARNASVFREVNALRTAELVRRAQAAGVQHFVHVSSLTA 118


>UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellular
           organisms|Rep: Nucleotide sugar epimerase -
           Synechococcus elongatus (Thermosynechococcus elongatus)
          Length = 338

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 14/125 (11%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLI-LPYRGDFYDA-------QRLKVCGDLGQVLFTPYH 410
           V G  GF+G      L + G ++I L    D+YD        + L +    GQ +F    
Sbjct: 5   VTGVAGFIGHGAALALLRRGDRVIGLDNLNDYYDVNLKKSRLEHLNISSQPGQFIFRKID 64

Query: 411 LLDEESIAKAVR-YS-NVVINLV---GRDYETKN-FKYNDVHVDGVRRIARICREEGVER 572
           L+D   + +    +S   VI+L    G  Y  +N F Y D ++ G   I   CR   VE 
Sbjct: 65  LVDRLGVNQLFADFSPQKVIHLAAQAGVRYSLENPFAYIDSNIVGFLHILEACRHHRVEH 124

Query: 573 FIHLS 587
            ++ S
Sbjct: 125 LVYAS 129


>UniRef50_Q67SF4 Cluster: Putative NADH-ubiquinone oxidoreductase;
           n=1; Symbiobacterium thermophilum|Rep: Putative
           NADH-ubiquinone oxidoreductase - Symbiobacterium
           thermophilum
          Length = 303

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 6/126 (4%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLIL------PYRGDFYDAQRLKVCGDLGQVLFTPY 407
           V  V G TGF+G Y+  +L + G ++I+        RG   D   ++  GD+        
Sbjct: 3   VVLVAGGTGFIGSYIVRRLTQDGHRVIVMSRDPGKARGRVPDGVEVR-AGDVTDGATLGP 61

Query: 408 HLLDEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLS 587
            L   E +  AV++ N  +     +   +   Y  V  +G  R+    R+ GV RF+++S
Sbjct: 62  ALAGAEIVVCAVQFPNHPV-----ENPRRGHTYIRVDGEGTVRLVGAARKAGVSRFVYIS 116

Query: 588 YLNAEE 605
                E
Sbjct: 117 GAGTRE 122


>UniRef50_Q5FL85 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=5; Lactobacillus|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase -
           Lactobacillus acidophilus
          Length = 242

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 16/39 (41%), Positives = 21/39 (53%)
 Frame = +3

Query: 249 ATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRL 365
           A VFG TG +G+ +C  L + G  L L Y     +AQ L
Sbjct: 4   AIVFGATGGIGKAICQDLAEDGWSLYLHYNTKMQEAQHL 42


>UniRef50_Q489H0 Cluster: Pseudouridine synthase; n=1; Colwellia
           psychrerythraea 34H|Rep: Pseudouridine synthase -
           Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
           (Vibriopsychroerythus)
          Length = 567

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
 Frame = +3

Query: 282 RYVCN---KLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDE 422
           RYV     KL K   ++ LP RGDF D  +  VC + G+   T + L++E
Sbjct: 446 RYVATIEGKLEKTSGEICLPLRGDFDDRPKQMVCHEHGKYAETHWQLIEE 495


>UniRef50_Q11DG7 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Mesorhizobium sp. BNC1|Rep: NAD-dependent
           epimerase/dehydratase - Mesorhizobium sp. (strain BNC1)
          Length = 305

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TGF+GR++   L K G +++   R  +  A R    GD+G    T +        +
Sbjct: 6   VTGATGFIGRHLVPVLLKRGHEVVEVGRRTYESAGRFVAVGDIGPT--TDW--------S 55

Query: 435 KAVRYSNVVINLVGRDY--ETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
            A+   + VI+L G  +  +     +  V+  G RR+A   +  G +  + LS + A E
Sbjct: 56  PALGGVDAVIHLAGLAHREDADEAMFFSVNDAGTRRLAEAAQAAGAKVLVALSSIAARE 114


>UniRef50_A5V7D1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Sphingomonas wittichii RW1|Rep: Short-chain
           dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
          Length = 265

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 15/33 (45%), Positives = 20/33 (60%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGD 344
           VA V G +G +GR +C KL   GT + L YR +
Sbjct: 20  VALVIGGSGGIGRAICEKLAAAGTDVALTYRSN 52


>UniRef50_A1WAD5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Acidovorax sp. JS42|Rep: NAD-dependent
           epimerase/dehydratase - Acidovorax sp. (strain JS42)
          Length = 328

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 425
           +  V G TGF+GR++   L + G ++ L  R +   A+  +   ++         L +E 
Sbjct: 17  LVAVTGATGFIGRHLIAALVQAGWRVRLLLRREPSGAEWRQSTPEV-----VAGSLDNEA 71

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVE-RFIHLSYLNAE 602
           ++A+ V   + VI+L G     +   +  V+  GV RIAR  ++   +  F+ +S L A 
Sbjct: 72  AVARLVEGVDAVIHLAGLIKAARRADFFAVNEQGVARIARATKQLSPDAHFLLVSSLAAR 131

Query: 603 E 605
           E
Sbjct: 132 E 132


>UniRef50_Q048B8 Cluster: Glycerophosphoryl diester
           phosphodiesterase; n=2; Lactobacillus delbrueckii subsp.
           bulgaricus|Rep: Glycerophosphoryl diester
           phosphodiesterase - Lactobacillus delbrueckii subsp.
           bulgaricus (strain ATCC BAA-365)
          Length = 473

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 16/44 (36%), Positives = 25/44 (56%)
 Frame = +3

Query: 492 KNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLV 623
           K+  Y D+ V  +R+   IC++ G E F+ L Y+N  E  K +V
Sbjct: 308 KDKVYEDLRVPTLRQYLEICKKYGKEAFLELKYINNMEALKEVV 351


>UniRef50_A7BY73 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Beggiatoa sp. PS|Rep: NAD-dependent
           epimerase/dehydratase - Beggiatoa sp. PS
          Length = 308

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 2/117 (1%)
 Frame = +3

Query: 261 GCTGFVGRYVCNKLGKIGTQLILPYRG-DFYDAQRLKVCGDLGQVLFTPYHLLDEESI-A 434
           G +GF+G+++ + L   G Q++   R  + + A+  +V     + L   Y    E  I  
Sbjct: 7   GASGFIGQHLLSALMAKGYQIVACVRQPNQWQARFPEV-----KWLACDYAKDHEPHIWL 61

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
             +   +VVIN VG   ET+  ++ D+H      + +   + G+ + + +S L A+E
Sbjct: 62  PRLEQIDVVINAVGIIRETRGQRFEDLHTHAPIALFKAAEQLGIRKILQISALGADE 118


>UniRef50_A3TUE1 Cluster: Putative uncharacterized protein; n=3;
           Rhodobacteraceae|Rep: Putative uncharacterized protein -
           Oceanicola batsensis HTCC2597
          Length = 288

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 26/116 (22%), Positives = 51/116 (43%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TG++GR++C +  + G  +    R    DA+R +   D    +     +   E++ 
Sbjct: 5   VAGATGYLGRFLCAEYARRGHHVTALVR----DARRAEGLAD----VLVEAEVTRPETLR 56

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
             +   ++V++ +G   +     Y +V       + R     GV RF ++  LNA+
Sbjct: 57  GIMDGMDLVVSSLGITRQADGLGYLEVDFQANLNLLREAETAGVRRFAYVHVLNAD 112


>UniRef50_Q4XFA1 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium chabaudi|Rep: Putative uncharacterized
           protein - Plasmodium chabaudi
          Length = 61

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 17/46 (36%), Positives = 25/46 (54%)
 Frame = +3

Query: 168 NYSSDRKPNLAAYKRGTGGRSSFNGIVATVFGCTGFVGRYVCNKLG 305
           NY S   PNL+  KR     SSF+ + A +  CT  +  ++ NK+G
Sbjct: 14  NYISIHHPNLSFLKRVENIASSFSILYAVICTCTSLIFPFLINKVG 59


>UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3;
           Bordetella|Rep: Putative oxidoreductase - Bordetella
           parapertussis
          Length = 262

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
 Frame = +3

Query: 240 GIVATVFGCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLL 416
           G VA + G  G +G     +    G  L +L  R D  +    ++CG  GQ +     + 
Sbjct: 16  GRVALITGAAGGIGSAAALRFAAEGAALALLDRRPDAIEQLAGRICGQGGQAIGVAADVT 75

Query: 417 DEESIAKAVR 446
           D++S+ +AVR
Sbjct: 76  DDDSVRQAVR 85


>UniRef50_Q7UXZ2 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=2;
           Planctomycetaceae|Rep: 3-beta-hydroxysteroid
           dehydrogenase - Rhodopirellula baltica
          Length = 339

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 1/112 (0%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V GC+GF+G  +  +L +   +++   R +  D  R  +    G        LLD E +A
Sbjct: 6   VTGCSGFLGGEIVRQLLQRDCEVVGLSRRETADLVRAGMTHHRGD-------LLDTEYLA 58

Query: 435 KAVRYSNVVINLVGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLS 587
           + +  ++VVI+         +++ Y D +V   R + + C+E GV + I+ S
Sbjct: 59  RVIAGADVVIHTAAVAGVWGSWQHYFDNNVVASRNVLQACQELGVSQLIYTS 110


>UniRef50_O66532 Cluster: NADH dehydrogenase; n=2; Aquifex|Rep: NADH
           dehydrogenase - Aquifex aeolicus
          Length = 315

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 4/121 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           + G TGFVGR++  +L   G ++    R +    +RL   G+  QV     +  +++SI 
Sbjct: 5   ITGATGFVGRHIVRELLNRGYEVHAGVR-NLSKLERL--FGN--QVKGYIVNFDEKDSIR 59

Query: 435 KAVRYSN--VVINLVGRDYE--TKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAE 602
           +A+   N   VI+L+G  YE   K   +  VH    + +  + +   V++F+ +S L   
Sbjct: 60  EALGKVNPDFVIHLIGILYEEKKKGITFERVHYGHTKNLVEVSKGFNVKKFLFMSALGTH 119

Query: 603 E 605
           +
Sbjct: 120 D 120


>UniRef50_A1ULW0 Cluster: NAD-dependent epimerase/dehydratase; n=4;
           Mycobacterium|Rep: NAD-dependent epimerase/dehydratase -
           Mycobacterium sp. (strain KMS)
          Length = 325

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 33/122 (27%), Positives = 51/122 (41%)
 Frame = +3

Query: 237 NGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLL 416
           + I   V G TG++G  +   L   G Q+    R       +L       QV      L+
Sbjct: 3   DNIRCLVTGATGYIGGRLVPALLDRGLQV----RAMARTPGKLDDAPWRAQVEVAKGDLM 58

Query: 417 DEESIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLN 596
           D ES+A A    +VV  LV     +KNF   +   +    +    ++ GV R ++LS L+
Sbjct: 59  DRESLAAAFEGMDVVYYLVHSMGTSKNFVAEE--AESAHNVVAAAKQAGVRRVVYLSGLH 116

Query: 597 AE 602
            E
Sbjct: 117 PE 118


>UniRef50_A0LUB4 Cluster: Uncharacterised conserved protein
           UCP033563; n=1; Acidothermus cellulolyticus 11B|Rep:
           Uncharacterised conserved protein UCP033563 -
           Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
          Length = 426

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +3

Query: 330 PYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 425
           P+RG  YDA R+   GD+G+VL  PY ++D++
Sbjct: 14  PFRGIRYDAARV---GDIGRVLAPPYDVIDDD 42


>UniRef50_Q3KN81 Cluster: Leucoanthocyanidin reductase; n=3;
           Spermatophyta|Rep: Leucoanthocyanidin reductase - Pinus
           taeda (Loblolly pine)
          Length = 359

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQR--LKVCGDLG-QVLFTPYHLLDEE 425
           + G TGF+GR+V     K G       R     ++   ++   D G QV++   H  D  
Sbjct: 62  IIGATGFIGRFVAEASVKSGRPTYALVRPTTLSSKPKVIQSLVDSGIQVVYGCLH--DHN 119

Query: 426 SIAKAVRYSNVVINLVG 476
           S+ KA+R  +VVI+ VG
Sbjct: 120 SLVKAIRQVDVVISTVG 136


>UniRef50_Q89WS9 Cluster: Bll0599 protein; n=1; Bradyrhizobium
           japonicum|Rep: Bll0599 protein - Bradyrhizobium
           japonicum
          Length = 272

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 1/122 (0%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TG +GR + ++L + G  + +  R            GDL         L D +++ 
Sbjct: 6   VTGGTGHLGRDIVDRLVRSGRHVRVLARSPGTRPDVEWAIGDLATGAGLRDALHDVDTVI 65

Query: 435 KAVRYSNVVINLVGRDYETKNFKY-NDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 611
            A  YS +     G    T  F   + V V+G  R+   C E  V  F+H+S +  +E  
Sbjct: 66  NAATYSPIARR--GGIRPTDFFTSPSAVDVEGTARLLSSCGEARVRHFLHVSIVGLDEAT 123

Query: 612 KP 617
            P
Sbjct: 124 LP 125


>UniRef50_Q6LH31 Cluster: Putative uncharacterized protein CT0995;
           n=4; Vibrionales|Rep: Putative uncharacterized protein
           CT0995 - Photobacterium profundum (Photobacterium sp.
           (strain SS9))
          Length = 287

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 18/59 (30%), Positives = 29/59 (49%)
 Frame = +3

Query: 453 NVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLK 629
           +VVI+ +G   +     Y DV       + +     GV +FI +S  NAE++P   +LK
Sbjct: 70  DVVISCLGITRQRDGLGYMDVDYQANLNLLQEAERAGVSKFIDVSAFNAEKYPSVRLLK 128


>UniRef50_Q2RKH0 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Firmicutes|Rep: NAD-dependent epimerase/dehydratase -
           Moorella thermoacetica (strain ATCC 39073)
          Length = 323

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 8/119 (6%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQL--ILPY--RGDFYDAQRLKVCGDLGQVLFTPYHLLDE 422
           V G  GF+G ++  KL + G ++   + Y  R  +   +  +V  D+   +FT   + D 
Sbjct: 5   VTGAGGFIGSHLTEKLVREGHKVRAFVHYNSRNTWGWLEESEVKDDIE--VFTG-DIRDY 61

Query: 423 ESIAKAVRYSNVVINL---VGRDYE-TKNFKYNDVHVDGVRRIARICREEGVERFIHLS 587
           +S+  ++R   VV +L   +G  Y       Y   +V+G   I +  REEG+ R +H S
Sbjct: 62  DSVRASLRGIEVVFHLAALIGIPYSYVTPVAYIKTNVEGTYNICQAAREEGLRRVVHTS 120


>UniRef50_A3ZLP8 Cluster: NAD-dependent epimerase/dehydratase family
           protein/3- betahydroxysteroid dehydrogenase/isomerase
           family protein; n=1; Blastopirellula marina DSM
           3645|Rep: NAD-dependent epimerase/dehydratase family
           protein/3- betahydroxysteroid dehydrogenase/isomerase
           family protein - Blastopirellula marina DSM 3645
          Length = 339

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 27/95 (28%), Positives = 39/95 (41%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TGF+GRY+C +L   G  L    R         +    LG V      L +   + 
Sbjct: 6   VTGATGFIGRYLCRRLVADGHSLRCAVR----QTSATEPLEQLG-VELVEVDLSNPHDLE 60

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRI 539
           +A+     + ++ G    T   K   V+ DG RRI
Sbjct: 61  QAIEGCEAIFHVAGLICATAPEKLFHVNRDGTRRI 95


>UniRef50_A0YNT9 Cluster: Putative uncharacterized protein; n=1;
           Lyngbya sp. PCC 8106|Rep: Putative uncharacterized
           protein - Lyngbya sp. PCC 8106
          Length = 341

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 31/112 (27%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G +GF+G  +  +L + G  + +     + D  R K       + F    + D E +A
Sbjct: 5   VTGGSGFLGNLIARRLQERGEDVSI--LDIWEDPTRPK------DIQFIQCDIRDREGVA 56

Query: 435 KAVRYSNVVINLVGRDYETKNF-KYNDVHVDGVRRIARICREEGVERFIHLS 587
           KA++  ++V + V     TK+  K+ +V+V G +  A    + GV+ FIH+S
Sbjct: 57  KAMKGIDIVHHNVALVPLTKSGNKFWEVNVKGSQIAAEEAVKAGVQSFIHMS 108


>UniRef50_A0VU05 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Dinoroseobacter shibae DFL 12|Rep: NAD-dependent
           epimerase/dehydratase - Dinoroseobacter shibae DFL 12
          Length = 880

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 5/123 (4%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKL---GKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEE 425
           + GCTGF+G  +  KL   G     L+LP  GD        V  D  Q+      L D +
Sbjct: 531 ITGCTGFIGTNLIPKLLAKGYTIRALVLPGTGD--------VLPDSPQIELIEGGLGDTD 582

Query: 426 SIAKAVRYSNVVINLVGRDYETKNF-KYNDVHVDGVRRIARICREEGV-ERFIHLSYLNA 599
           ++A+ V  + VV+++  R   +    +  + +V+G   + R     G   RF+  S + A
Sbjct: 583 ALARLVEGARVVLHMAARLAGSCTLVELRETNVEGTHNLIRAVNAAGACARFVFCSSVAA 642

Query: 600 EEH 608
            ++
Sbjct: 643 YQN 645


>UniRef50_Q8FSM1 Cluster: Putative UDP-galactose 4-epimerase; n=1;
           Corynebacterium efficiens|Rep: Putative UDP-galactose
           4-epimerase - Corynebacterium efficiens
          Length = 314

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 26/115 (22%), Positives = 54/115 (46%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           + G  GF+GRY+ +KL     ++I   R D    Q ++V   +   + +    +   S  
Sbjct: 5   ITGANGFIGRYLVDKLASTH-EVIAAVRTDTVFPQGVEV--RVIPSIDSQSDWVGLLSDI 61

Query: 435 KAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
             V +    ++++    E    ++ +V+  G  ++A    E+GV+RF+ +S + A
Sbjct: 62  DVVVHLAARVHVMNESAEDPLSEFREVNALGTSKLAGAAAEQGVKRFVFMSSIKA 116


>UniRef50_Q7WTE7 Cluster: NanG4; n=1; Streptomyces
           nanchangensis|Rep: NanG4 - Streptomyces nanchangensis
          Length = 346

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 31/124 (25%), Positives = 55/124 (44%), Gaps = 3/124 (2%)
 Frame = +3

Query: 222 GRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFT 401
           G  +  G    V G +G++GR++C+  G  G Q++   RG      R  V GD  + +  
Sbjct: 11  GDEALAGTPVLVLGGSGYLGRHICSAFGAAGAQVVPVSRG-----ARGGVDGDGCRSVRL 65

Query: 402 PYHLLDEESIAK--AVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIA-RICREEGVER 572
                  + +A+  A   + V++N  G  +     +  + + + V R+A  + R  G  R
Sbjct: 66  DLTAAGPDELARLCAGTGARVLVNASGAVWGGGERQMAEANTELVGRLAGAVARLPGRPR 125

Query: 573 FIHL 584
            IHL
Sbjct: 126 LIHL 129


>UniRef50_Q1PXL6 Cluster: Strongly similar to leucine dehydrogenase;
           n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to leucine dehydrogenase - Candidatus Kuenenia
           stuttgartiensis
          Length = 349

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +3

Query: 222 GRSSFNGIVATVFGCTGFVGRYVCNKLGKIGTQLIL 329
           GR S +G+  +V G  G VGR++C  L + G +LI+
Sbjct: 163 GRDSLHGLTVSVQG-VGNVGRHLCKNLSEAGAKLII 197


>UniRef50_Q1IZY4 Cluster: NAD-dependent epimerase/dehydratase; n=2;
           Deinococcus|Rep: NAD-dependent epimerase/dehydratase -
           Deinococcus geothermalis (strain DSM 11300)
          Length = 309

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 2/119 (1%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TGFVG+ +  +L   G  +    R            G L         + D  S+ 
Sbjct: 18  VTGATGFVGQALVRELVSRGHTVFAGSRSG----------GALPGATGLRLDVTDPGSVL 67

Query: 435 KAVRYSN--VVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEE 605
           +AV  ++   V++LVG   E     +  VHV+G R +      +   R++H+S L A+E
Sbjct: 68  RAVGEADPEAVVHLVGIIQEEGTQTFRRVHVEGTRNVLAATPRQA--RYLHMSALGADE 124


>UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=9;
           Bacteria|Rep: NAD-dependent epimerase/dehydratase -
           Anaeromyxobacter sp. Fw109-5
          Length = 373

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 11/120 (9%)
 Frame = +3

Query: 261 GCTGFVGRYVCNKLGKIGTQLI-LPYRGDFYDAQ----RLKVCGDLGQVLFTPYHLLDEE 425
           GC GF+G +V  +L + G ++  L    D+YD      RL +        FT   + D E
Sbjct: 49  GCAGFIGSHVARRLLRDGHEVSGLDNLNDYYDPSLKRARLALLAPERGFRFTAADVADRE 108

Query: 426 SIAKAVRYS--NVVINL---VGRDYETKNFK-YNDVHVDGVRRIARICREEGVERFIHLS 587
           ++   +  +    V++L   VG     +N + Y + ++DG   +   C   GV   ++ S
Sbjct: 109 ALDAVLDEAEPEYVVHLAAQVGVRNSVRNPRAYAETNLDGFFNVLDGCARRGVRHLVYAS 168


>UniRef50_A6EIS2 Cluster: Probable dehydrogenase/reductase; n=1;
           Pedobacter sp. BAL39|Rep: Probable
           dehydrogenase/reductase - Pedobacter sp. BAL39
          Length = 249

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 3/82 (3%)
 Frame = +3

Query: 240 GIVATVFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDA-QRLKVCGDLGQVLFTPYHLL 416
           G VA + G +  +GR +  KL   G QLIL Y  D   A +  K+  D G      YHL+
Sbjct: 7   GKVALITGASKGIGRGIAEKLASEGLQLILNYSSDDRAAHETAKLMDDYG----VNYHLI 62

Query: 417 --DEESIAKAVRYSNVVINLVG 476
             D  S+    R     +N  G
Sbjct: 63  KADVSSLTAIERLYQQALNKFG 84


>UniRef50_A1VMB7 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Comamonadaceae|Rep: NAD-dependent epimerase/dehydratase
           - Polaromonas naphthalenivorans (strain CJ2)
          Length = 305

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 18/61 (29%), Positives = 26/61 (42%)
 Frame = +3

Query: 459 VINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHPKPLVLKKPS 638
           V+N VG   +  +     +H D  + +   C  +GV R IHLS L     P      K +
Sbjct: 75  VVNAVGVLRDGPHTPMQAIHTDVPKALFNACARQGVRRVIHLSALGIASSPSRYATAKRA 134

Query: 639 A 641
           A
Sbjct: 135 A 135


>UniRef50_Q9FRM0 Cluster: NADPH oxidoreductase, putative;
           12234-10951; n=4; rosids|Rep: NADPH oxidoreductase,
           putative; 12234-10951 - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 323

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIG-TQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH--LLDEE 425
           V G TG +G+ +     K G + L L       D  + K   +      T  H  L D E
Sbjct: 10  VIGGTGHIGKLIIEASVKAGHSTLALVREASLSDPNKGKTVQNFKDFGVTLLHGDLNDHE 69

Query: 426 SIAKAVRYSNVVINLVG 476
           S+ KA++ ++VVI+ VG
Sbjct: 70  SLVKAIKQADVVISTVG 86


>UniRef50_Q23086 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 374

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 28/127 (22%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGT-QLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESI 431
           + G  GF+G +V + L KIG  + I+       + + +K+  D   + +     LD++ +
Sbjct: 6   IVGGGGFLGAHVISALQKIGCKERIIVVDPCPQEFKTIKI--DKSNISYIKASFLDDKVL 63

Query: 432 AKAVRYSNVVINL--VGRD--YETKNFKYNDVHVDGVRRIARICREEGVERFIHLSYLNA 599
              +  ++ V++L  VG            ++ +V+G +++ + C+  GV+RF++ S +  
Sbjct: 64  ENILNGASAVVHLAAVGHTGLIAGDRKSVHNFNVNGTKQLIKQCKALGVKRFLYASSVAV 123

Query: 600 EEHPKPL 620
               +PL
Sbjct: 124 SFIGEPL 130


>UniRef50_P52577 Cluster: Isoflavone reductase homolog P3; n=30;
           Spermatophyta|Rep: Isoflavone reductase homolog P3 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 310

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIG-TQLILPYRGDFYDAQRLKVCGDLGQVLFTPYH--LLDEE 425
           V G TG++G+++     K G +   L       D  + K       +  T  H  L D E
Sbjct: 10  VIGGTGYIGKFLVEASAKAGHSTFALVREATLSDPVKGKTVQSFKDLGVTILHGDLNDHE 69

Query: 426 SIAKAVRYSNVVINLVG 476
           S+ KA++  +VVI+ VG
Sbjct: 70  SLVKAIKQVDVVISTVG 86


>UniRef50_UPI00015B4F2F Cluster: PREDICTED: similar to
           hydroxysteroid dehydrogenase; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to hydroxysteroid
           dehydrogenase - Nasonia vitripennis
          Length = 379

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
 Frame = +3

Query: 411 LLDEESIAKAVRYSNVVIN---LVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIH 581
           L + ES  +A + ++VV++   LV  DY     +    +VD    + ++C EE V R +H
Sbjct: 67  LTNLESCREAFKGADVVLHCAALVSYDYPPDVVELRKNNVDATENVIKLCVEENVGRLVH 126

Query: 582 LS 587
            S
Sbjct: 127 CS 128


>UniRef50_UPI0000DAE763 Cluster: hypothetical protein
           Rgryl_01001156; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01001156 - Rickettsiella
           grylli
          Length = 341

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 31/138 (22%), Positives = 60/138 (43%), Gaps = 9/138 (6%)
 Frame = +3

Query: 246 VATVFGCTGFVGRYVCNKLGKIGTQLIL--PYRGDFYDAQRLKVCGDLGQVLFTPYHLLD 419
           V  V G TGF+G +VC      G  +++    R  +++      C    ++ F    +LD
Sbjct: 4   VILVTGGTGFIGSHVCVAFANAGYNIVILDNLRNSYFEVVDRLECICKFRLKFIEGDILD 63

Query: 420 EESIAKAVRYSNV--VINLVGRDYETKNFK-----YNDVHVDGVRRIARICREEGVERFI 578
              +      +N+  VI+L G    +++ K     YN+ +V+G   +    R+  V++ I
Sbjct: 64  SNLLDHIFFENNISAVIHLAGLKAVSESIKNPLKCYNN-NVEGTLTLINAMRKSNVKKLI 122

Query: 579 HLSYLNAEEHPKPLVLKK 632
             S       PK + +++
Sbjct: 123 FSSSAAVYGEPKCVPIRE 140


>UniRef50_UPI0000499078 Cluster: acyl-CoA synthetase; n=1; Entamoeba
           histolytica HM-1:IMSS|Rep: acyl-CoA synthetase -
           Entamoeba histolytica HM-1:IMSS
          Length = 1047

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 15/37 (40%), Positives = 24/37 (64%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRL 365
           +FGC GFVG+++  +L  IG ++I   RG+ Y  + L
Sbjct: 724 LFGCNGFVGKFILREL--IGKEVICIVRGNNYQEKVL 758


>UniRef50_Q9L3U6 Cluster: Putative TDP-glucose dehydratase; n=1;
           Streptomyces rochei|Rep: Putative TDP-glucose
           dehydratase - Streptomyces rochei (Streptomyces
           parvullus)
          Length = 327

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 29/110 (26%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
 Frame = +3

Query: 261 GCTGFVGRYVCNKLGKIGTQL-ILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIAK 437
           G +GF+G  +  +L  +G+Q  + P    F  A RL V     ++ F    LLD + +  
Sbjct: 17  GASGFIGGRLVERL-ILGSQARVRPVVRGFGRAARLSVLPQ-ERLEFRQADLLDTDGLRA 74

Query: 438 AVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREEGVERFIHLS 587
           A    + V++    +  T+  ++  + V+G   +    R  GV R +HLS
Sbjct: 75  AFEGCDTVVHCAFGNTGTEAERWA-MSVEGTAGVLAAARAAGVRRVVHLS 123


>UniRef50_Q0LC55 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Herpetosiphon aurantiacus ATCC 23779|Rep: NAD-dependent
           epimerase/dehydratase - Herpetosiphon aurantiacus ATCC
           23779
          Length = 308

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 1/120 (0%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYRGDFYDAQRLKVCGDLGQVLFTPYHLLDEESIA 434
           V G TG+VG  +  KL +    + +  R     AQ+L      G V      + D ES+ 
Sbjct: 4   VTGGTGYVGSRLIEKLRQRPEPVRVLVRTP-EKAQKLVA----GNVSIVKGDVTDPESLI 58

Query: 435 KAVRYSNVVINLVGRDYETKN-FKYNDVHVDGVRRIARICREEGVERFIHLSYLNAEEHP 611
            A++  + VI+LV    E      +  ++      +    +  GV+RF+H+S L     P
Sbjct: 59  AAMKGVSTVIHLVAIIRERSGGISFERMNYQATVNVVDAAKAAGVKRFLHMSALGVVNDP 118


>UniRef50_Q0AIT5 Cluster: NAD-dependent epimerase/dehydratase; n=3;
           Nitrosomonadaceae|Rep: NAD-dependent
           epimerase/dehydratase - Nitrosomonas eutropha (strain
           C71)
          Length = 307

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 36/121 (29%), Positives = 57/121 (47%), Gaps = 4/121 (3%)
 Frame = +3

Query: 255 VFGCTGFVGRYVCNKLGKIGTQLILPYR--GDFYDAQRLK-VCGDLGQVLFTPYHLLDEE 425
           V G TGF+GR +  KL + G ++    R      D+  ++ + GDLG        L D  
Sbjct: 7   VTGATGFIGRILIAKLAESGWKIRALARCISSQKDSPFIEWISGDLG----CNNALRDLV 62

Query: 426 SIAKAVRYSNVVINLVGRDYETKNFKYNDVHVDGVRRIARICREE-GVERFIHLSYLNAE 602
           S A+AV +   V+   G+ ++     +   +V G R I R+  +     RF+H+S L A 
Sbjct: 63  SGAEAVIHCAGVVK--GKSWD----DFYQTNVIGTRNILRVASDSTSCSRFLHISSLAAR 116

Query: 603 E 605
           E
Sbjct: 117 E 117


>UniRef50_A5E1Q4 Cluster: Predicted protein; n=1; Lodderomyces
           elongisporus NRRL YB-4239|Rep: Predicted protein -
           Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 185

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 20/96 (20%), Positives = 42/96 (43%)
 Frame = +3

Query: 51  YELSQYLSHKMAAIALKTQATSKLLHLNGSMSVVYIKAANYSSDRKPNLAAYKRGTGGRS 230
           + + Q  S +   + LK     KL++          K      +++ ++  Y +    +S
Sbjct: 48  FNVGQIFSARGVKLLLKLFCIKKLINKKRKKRKKKEKGKKRQREKEKSMNLYHQEFAPKS 107

Query: 231 SFNGIVATVFGCTGFVGRYVCNKLGKIGTQLILPYR 338
           SF+ +   V  C+ ++  YVC  +   G Q+I P++
Sbjct: 108 SFSILCKVVDSCSIYI--YVCGYVALFGFQIIKPFK 141


>UniRef50_Q67477 Cluster: 3 beta-hydroxysteroid dehydrogenase/Delta
           5-->4-isomerase (3-beta-HSD) [Includes:
           3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC
           1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase)
           (Progesterone reductase); Steroid Delta-isomerase (EC
           5.3.3.1) (Delta- 5-3-ketosteroid isomerase)]; n=3;
           Avipoxvirus|Rep: 3 beta-hydroxysteroid
           dehydrogenase/Delta 5-->4-isomerase (3-beta-HSD)
           [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase
           (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid
           dehydrogenase) (Progesterone reductase); Steroid
           Delta-isomerase (EC 5.3.3.1) (Delta- 5-3-ketosteroid
           isomerase)] - Fowlpox virus (FPV)
          Length = 370

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 29/126 (23%), Positives = 62/126 (49%), Gaps = 7/126 (5%)
 Frame = +3

Query: 243 IVATVFGCTGFVGRYVCNKLGKIGTQL----ILPYRGDFYDAQRLKVCGDLGQVLFTPYH 410
           +V  V G  GF+GR++ N L    + L    +   R D +    ++ C ++ +++     
Sbjct: 4   LVYVVTGGCGFLGRHIINNLILFESSLKEVRVYDIRIDQWLLDLVEKC-NIIKIVPVIGD 62

Query: 411 LLDEESIAKAVRYSNVVINLVG-RDYETK--NFKYNDVHVDGVRRIARICREEGVERFIH 581
           + ++ ++ +A+R ++VVI++    D   K  N    DV+++G + +   C   GV   ++
Sbjct: 63  VRNKSTLDEALRSADVVIHIASINDVAGKFTNDSIMDVNINGTKNVVDSCLYNGVRVLVY 122

Query: 582 LSYLNA 599
            S  +A
Sbjct: 123 TSSYSA 128


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 603,290,318
Number of Sequences: 1657284
Number of extensions: 11619301
Number of successful extensions: 27196
Number of sequences better than 10.0: 128
Number of HSP's better than 10.0 without gapping: 26422
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 27128
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48541014171
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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