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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= maV30161
         (465 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component sub...   106   2e-22
UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alph...    95   9e-19
UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component sub...    94   2e-18
UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,...    89   6e-17
UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-...    84   1e-15
UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whol...    79   6e-14
UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit...    75   8e-13
UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component sub...    72   7e-12
UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=...    71   9e-12
UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit...    63   3e-09
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid...    62   4e-09
UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component sub...    62   6e-09
UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit...    61   1e-08
UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component sub...    57   2e-07
UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component sub...    57   2e-07
UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alp...    56   5e-07
UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alp...    53   3e-06
UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, al...    50   2e-05
UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alp...    50   2e-05
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al...    49   4e-05
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea...    49   6e-05
UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alp...    47   2e-04
UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alp...    47   2e-04
UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3; Prote...    45   7e-04
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|...    45   7e-04
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n...    45   7e-04
UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1 ...    45   0.001
UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte...    44   0.002
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub...    43   0.004
UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, al...    42   0.005
UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa ...    42   0.009
UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit...    42   0.009
UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3; Prote...    41   0.012
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R...    40   0.020
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex...    40   0.035
UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALP...    39   0.047
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm...    39   0.062
UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|R...    38   0.081
UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent) a...    38   0.14 
UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha...    37   0.19 
UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E...    37   0.19 
UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8; Chla...    37   0.25 
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al...    36   0.33 
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter...    36   0.43 
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet...    36   0.57 
UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3; Actin...    35   1.0  
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB...    34   1.3  
UniRef50_A2FVJ6 Cluster: DnaK protein; n=1; Trichomonas vaginali...    34   1.8  
UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit (...    34   1.8  
UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1; Chlor...    33   3.1  
UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1; Proch...    32   5.4  
UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol ox...    32   5.4  
UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway sig...    32   7.1  
UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent) a...    31   9.4  
UniRef50_A5CYF4 Cluster: Putative uncharacterized protein; n=1; ...    31   9.4  

>UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component
           subunit alpha type I, mitochondrial precursor; n=10;
           cellular organisms|Rep: Pyruvate dehydrogenase E1
           component subunit alpha type I, mitochondrial precursor
           - Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
          Length = 396

 Score =  106 bits (255), Expect = 2e-22
 Identities = 49/93 (52%), Positives = 68/93 (73%)
 Frame = +1

Query: 187 ITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEXLTILRR 366
           +  V+  V+A + + ++  EATF+ KP+KLHKLD GP  +  +T EDA+  Y  +  +RR
Sbjct: 11  VPTVSPSVMAISVRLAST-EATFQTKPFKLHKLDSGPDINVHVTKEDAVHYYTQMLTIRR 69

Query: 367 IETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           +E+A+GNLYKEK +RGFCHLYSGQEA AVG +A
Sbjct: 70  MESAAGNLYKEKKVRGFCHLYSGQEACAVGTKA 102


>UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alpha
           1; n=3; Tetrapoda|Rep: Pyruvate dehydrogenase
           (Lipoamide) alpha 1 - Xenopus tropicalis (Western clawed
           frog) (Silurana tropicalis)
          Length = 369

 Score = 94.7 bits (225), Expect = 9e-19
 Identities = 45/113 (39%), Positives = 66/113 (58%)
 Frame = +1

Query: 127 IIDKMSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATS 306
           ++  +S+++   A+        +    +VA+        EATF+IK   +H+L++GP T 
Sbjct: 4   MLSLLSRVLKGPAQKPVTGAANEAVRVMVASRNYADFASEATFDIKKCDVHRLEEGPPTQ 63

Query: 307 ATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           A LT E  L+ Y  +  +RR+E  S  LYK+KIIRGFCHLY GQEA  VG+ A
Sbjct: 64  AVLTREQGLQYYRTMQTIRRMELKSDQLYKQKIIRGFCHLYDGQEACCVGLEA 116


>UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component
           subunit alpha, somatic form, mitochondrial precursor;
           n=110; cellular organisms|Rep: Pyruvate dehydrogenase E1
           component subunit alpha, somatic form, mitochondrial
           precursor - Homo sapiens (Human)
          Length = 390

 Score = 93.9 bits (223), Expect = 2e-18
 Identities = 46/109 (42%), Positives = 68/109 (62%)
 Frame = +1

Query: 139 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 318
           M K++ + ++ L+G +    +  +VA+    +   +ATFEIK   LH+L++GP  +  LT
Sbjct: 1   MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57

Query: 319 SEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
            ED LK Y  +  +RR+E  +  LYK+KIIRGFCHL  GQEA  VG+ A
Sbjct: 58  REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEA 106


>UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,
           partial; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein, partial -
           Strongylocentrotus purpuratus
          Length = 378

 Score = 88.6 bits (210), Expect = 6e-17
 Identities = 37/65 (56%), Positives = 50/65 (76%)
 Frame = +1

Query: 265 PYKLHKLDQGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 444
           P+KLHKL++GP  ++ LT ++AL  Y  +  +RR+ETA+  LYK K +RGFCHLYSGQEA
Sbjct: 165 PFKLHKLEEGPKKTSVLTKDEALDYYHKMQTIRRMETAAATLYKSKEVRGFCHLYSGQEA 224

Query: 445 VAVGM 459
            AVG+
Sbjct: 225 CAVGI 229


>UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 479

 Score = 84.2 bits (199), Expect = 1e-15
 Identities = 37/65 (56%), Positives = 47/65 (72%)
 Frame = +1

Query: 268 YKLHKLDQGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 447
           +K + L+ GP     L+ EDAL +Y  +  LRR ET +GN YKE+ IRGFCHLY+GQEAV
Sbjct: 43  FKCYDLENGPTMDVELSREDALTMYTQMLELRRFETVAGNYYKERKIRGFCHLYNGQEAV 102

Query: 448 AVGMR 462
           AVGM+
Sbjct: 103 AVGMK 107


>UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF10102,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 491

 Score = 78.6 bits (185), Expect = 6e-14
 Identities = 34/64 (53%), Positives = 44/64 (68%)
 Frame = +1

Query: 274 LHKLDQGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 453
           LH+L++GP   A LT E  L+ Y  +  +RR+E  +  LYK+KIIRGFCHLY GQEA A 
Sbjct: 5   LHRLEEGPPEKAELTREQGLQYYRTMQTIRRMELKADQLYKQKIIRGFCHLYDGQEACAA 64

Query: 454 GMRA 465
           G+ A
Sbjct: 65  GIEA 68


>UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
           n=6; Spirotrichea|Rep: Pyruvate dehydrogenase E1 alpha
           subunit - Euplotes sp. BB-2004
          Length = 389

 Score = 74.9 bits (176), Expect = 8e-13
 Identities = 32/71 (45%), Positives = 47/71 (66%), Gaps = 1/71 (1%)
 Frame = +1

Query: 256 EIKPYKLHKLDQGPA-TSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYS 432
           E+  +K+H++++    T AT T  + L  Y+ + ++RR+E  S  LYK K IRGFCHLY 
Sbjct: 30  ELPKFKVHRIEESELPTKATTTKSELLNYYKDMALMRRVEIVSDMLYKNKWIRGFCHLYD 89

Query: 433 GQEAVAVGMRA 465
           GQE++ VGM A
Sbjct: 90  GQESITVGMEA 100


>UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component
           subunit alpha-2, mitochondrial precursor; n=33; cellular
           organisms|Rep: Pyruvate dehydrogenase E1 component
           subunit alpha-2, mitochondrial precursor - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 393

 Score = 71.7 bits (168), Expect = 7e-12
 Identities = 33/67 (49%), Positives = 46/67 (68%)
 Frame = +1

Query: 265 PYKLHKLDQGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 444
           P+  H L + P+ S   +SE+ L  +  +  +RR+E A+ +LYK K+IRGFCHLY GQEA
Sbjct: 43  PFTSH-LCESPSRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEA 101

Query: 445 VAVGMRA 465
           +AVGM A
Sbjct: 102 LAVGMEA 108


>UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=5;
           Intramacronucleata|Rep: Pyruvate dehydrogenase E1
           component - Tetrahymena thermophila SB210
          Length = 429

 Score = 71.3 bits (167), Expect = 9e-12
 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 1/102 (0%)
 Frame = +1

Query: 163 AKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPA-TSATLTSEDALKL 339
           AK +       V         KY+     T  ++ Y+   LD     T +T T E+ LKL
Sbjct: 41  AKLMISKFFNPVAGKTFNRLNKYAFSS-VTINLEGYQTKMLDGFKLPTQSTATKEELLKL 99

Query: 340 YEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           Y+ + ++R+IE A   LYK++ IRGFCHLY GQEAV  G+ A
Sbjct: 100 YKDMNVMRKIELACDKLYKQREIRGFCHLYDGQEAVISGIEA 141


>UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
           n=1; Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E1
           alpha subunit - Nyctotherus ovalis
          Length = 136

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 30/87 (34%), Positives = 52/87 (59%), Gaps = 1/87 (1%)
 Frame = +1

Query: 208 VVATNAKYSTKKEATFEIKPYKLHKLDQGPA-TSATLTSEDALKLYEXLTILRRIETASG 384
           ++ ++A++++  E   ++  Y++  LD+    T A    ++ LK Y  +   RR+E    
Sbjct: 11  IIGSSARFASTVE--IKLPQYEVFNLDKSILPTKAQTNRDEMLKYYHDMNFQRRVEIMCD 68

Query: 385 NLYKEKIIRGFCHLYSGQEAVAVGMRA 465
            +YK+K +RGFCHL  GQEAV+VG+ A
Sbjct: 69  EIYKKKEVRGFCHLMDGQEAVSVGVEA 95


>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
           <=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
           Catalytic activity: Pyruvate + Lipoamide <=>
           S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
          Length = 403

 Score = 62.5 bits (145), Expect = 4e-09
 Identities = 30/64 (46%), Positives = 44/64 (68%)
 Frame = +1

Query: 268 YKLHKLDQGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 447
           ++ + LD  P +  T T     +LY  ++++RR+E A+  LYKE+ IRGFCHL +GQEAV
Sbjct: 54  FETYNLDPPPYSLET-TKSQLKQLYYDMSLIRRMELAADKLYKEQKIRGFCHLSTGQEAV 112

Query: 448 AVGM 459
           AVG+
Sbjct: 113 AVGV 116


>UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component
           subunit alpha; n=62; Bacteria|Rep: Pyruvate
           dehydrogenase E1 component subunit alpha - Rhizobium
           meliloti (Sinorhizobium meliloti)
          Length = 348

 Score = 62.1 bits (144), Expect = 6e-09
 Identities = 30/61 (49%), Positives = 36/61 (59%)
 Frame = +1

Query: 280 KLDQGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           K D    T A  + ED LK Y  + ++RR E  +G LY    I GFCHLY GQEAV VGM
Sbjct: 20  KKDFAGGTIAEFSKEDDLKAYREMLLIRRFEEKAGQLYGMGFIGGFCHLYIGQEAVVVGM 79

Query: 460 R 462
           +
Sbjct: 80  Q 80


>UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
           n=2; Trypanosoma cruzi|Rep: Pyruvate dehydrogenase E1
           alpha subunit - Trypanosoma cruzi
          Length = 378

 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 34/70 (48%), Positives = 42/70 (60%), Gaps = 4/70 (5%)
 Frame = +1

Query: 262 KPYKLHKL---DQGPA-TSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLY 429
           KP+KLH     D  P  T+AT  +E   K  E +  +RR+E+     YK K IRGFCHLY
Sbjct: 21  KPFKLHTAGRDDVPPVPTTATYDTEQMKKCLEMMFRIRRMESLCDQSYKLKKIRGFCHLY 80

Query: 430 SGQEAVAVGM 459
            GQEA+ VGM
Sbjct: 81  IGQEAIPVGM 90


>UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component
           subunit alpha, mitochondrial precursor; n=34;
           Dikarya|Rep: Pyruvate dehydrogenase E1 component subunit
           alpha, mitochondrial precursor - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 420

 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 27/55 (49%), Positives = 36/55 (65%)
 Frame = +1

Query: 295 PATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           P  S   +    L++Y+ + I+RR+E A   LYK K IRGFCHL  GQEA+AVG+
Sbjct: 70  PDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAVGI 124


>UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component
           subunit alpha; n=38; Proteobacteria|Rep: Pyruvate
           dehydrogenase E1 component subunit alpha - Zymomonas
           mobilis
          Length = 354

 Score = 56.8 bits (131), Expect = 2e-07
 Identities = 25/48 (52%), Positives = 33/48 (68%)
 Frame = +1

Query: 322 EDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           E+ L+ Y  + ++RR E   G LY   +I GFCHLY GQEAVAVG++A
Sbjct: 37  EELLEFYRRMLMIRRFEERCGQLYGLGLIAGFCHLYIGQEAVAVGLQA 84


>UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alpha
           subunit, putative; n=5; Euglenozoa|Rep: Pyruvate
           dehydrogenase E1 component alpha subunit, putative -
           Leishmania major
          Length = 378

 Score = 55.6 bits (128), Expect = 5e-07
 Identities = 33/86 (38%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
 Frame = +1

Query: 214 ATNAKYSTKKEATFEIKPYKLH---KLDQGPA-TSATLTSEDALKLYEXLTILRRIETAS 381
           AT     TK       +P+KLH   + D  P  T A   +E   +    +  +RR+E+  
Sbjct: 5   ATRCLLDTKTVPLKPQRPFKLHTAGRTDMAPLPTQAVYDAEQLKQSLALMFRIRRMESLC 64

Query: 382 GNLYKEKIIRGFCHLYSGQEAVAVGM 459
              YK K IRGFCHLY GQEA+  GM
Sbjct: 65  DQSYKLKKIRGFCHLYIGQEAIPAGM 90


>UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alpha
           subunit; n=4; Bacteria|Rep: Pyruvate dehydrogenase E1
           component alpha subunit - Gluconobacter oxydans
           (Gluconobacter suboxydans)
          Length = 334

 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 24/56 (42%), Positives = 33/56 (58%)
 Frame = +1

Query: 292 GPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           G +    L+ E   + Y  + ++RR E  +G LY   +I GFCHLY GQEAV VG+
Sbjct: 9   GRSNGPALSPETMKRAYRDMLLVRRFEEKAGQLYGMGLIGGFCHLYIGQEAVVVGI 64


>UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, alpha
           subunit; n=1; Lentisphaera araneosa HTCC2155|Rep:
           Dehydrogenase complex, E1 component, alpha subunit -
           Lentisphaera araneosa HTCC2155
          Length = 320

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 24/48 (50%), Positives = 30/48 (62%)
 Frame = +1

Query: 322 EDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           E AL++ E +  +RR E      Y++K I GFCH Y GQEAVAVG  A
Sbjct: 7   EKALQMLEQMIRVRRFEEGCLKSYQQKFITGFCHTYIGQEAVAVGAMA 54


>UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alpha
           subunit, putative; n=1; Aspergillus fumigatus|Rep:
           Pyruvate dehydrogenase E1 component alpha subunit,
           putative - Aspergillus fumigatus (Sartorya fumigata)
          Length = 360

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 22/33 (66%), Positives = 28/33 (84%)
 Frame = +1

Query: 361 RRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           +R+E A+  LYK+K IRGFCHL +GQEAVAVG+
Sbjct: 81  QRLEIAADALYKQKKIRGFCHLSTGQEAVAVGI 113


>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
           subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
           component, alpha subunit - Geobacter sulfurreducens
          Length = 325

 Score = 49.2 bits (112), Expect = 4e-05
 Identities = 24/53 (45%), Positives = 31/53 (58%)
 Frame = +1

Query: 307 ATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           A L   + LK++E + + R  E +    Y +  I GF HLYSGQEAVAVG  A
Sbjct: 7   AILPDSELLKMHEQMVLSREFEESCAEQYTKGHITGFLHLYSGQEAVAVGATA 59


>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
           bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
           bacterium TAV2
          Length = 365

 Score = 48.8 bits (111), Expect = 6e-05
 Identities = 25/51 (49%), Positives = 31/51 (60%)
 Frame = +1

Query: 304 SATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 456
           +A LT    ++LY  +  +RR E  S   Y+ K I GF HLY GQEAVAVG
Sbjct: 28  NADLTPAARIELYRTMVRIRRFEERSLRAYQAKKIGGFLHLYIGQEAVAVG 78


>UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alpha
           subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate
           dehydrogenase (Lipoamide), alpha subunit - Plesiocystis
           pacifica SIR-1
          Length = 339

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 31/56 (55%)
 Frame = +1

Query: 295 PATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 462
           P T  +   ++ LK +  +  +RR E  +   Y    I GF HLY GQEA+AVG++
Sbjct: 11  PETLTSAGKDETLKAFREMLRIRRFEETAARAYTRGKISGFLHLYIGQEAIAVGVK 66


>UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alpha
           subunit; n=1; Candidatus Sulcia muelleri str. Hc
           (Homalodisca coagulata)|Rep: Pyruvate dehydrogenase E1
           component alpha subunit - Candidatus Sulcia muelleri
           str. Hc (Homalodisca coagulata)
          Length = 58

 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 20/50 (40%), Positives = 33/50 (66%)
 Frame = +1

Query: 310 TLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           T+ ++  LK Y+ ++  R+ E    +LY ++ IRGF HLY+GQEA+  G+
Sbjct: 3   TINNDIYLKWYKDMSFWRKFEDKCRSLYLKQKIRGFLHLYNGQEAIPAGL 52


>UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3;
           Proteobacteria|Rep: Dehydrogenase, E1 component -
           Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 339

 Score = 45.2 bits (102), Expect = 7e-04
 Identities = 21/45 (46%), Positives = 26/45 (57%)
 Frame = +1

Query: 325 DALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           D  +L   +   RR E  S   Y E+ + GF HLYSGQEAVA G+
Sbjct: 5   DRKRLLREMVFFRRFEDRSFEAYMERKVGGFLHLYSGQEAVATGV 49


>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
           Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
           (strain JS666 / ATCC BAA-500)
          Length = 337

 Score = 45.2 bits (102), Expect = 7e-04
 Identities = 22/43 (51%), Positives = 28/43 (65%)
 Frame = +1

Query: 328 ALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 456
           AL +   +  +RR+E     LY E+ IRGF HLY G+EAVAVG
Sbjct: 21  ALAVLAGMLRIRRMEEKCAQLYGEQKIRGFLHLYIGEEAVAVG 63


>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
           Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
           Plasmodium falciparum
          Length = 608

 Score = 45.2 bits (102), Expect = 7e-04
 Identities = 20/53 (37%), Positives = 30/53 (56%)
 Frame = +1

Query: 301 TSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           +   ++ E+   LYE + + R  E     LY  K + GF HLY+GQEAV+ G+
Sbjct: 184 SDVNISREEICTLYEDMYLGRLFENLVAKLYYNKRVNGFVHLYNGQEAVSTGI 236


>UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1
           alpha-subunit; n=2; Rhodobacterales|Rep: Tpp-dependent
           acetoin dehydrogenase e1 alpha-subunit - Rhodobacterales
           bacterium HTCC2654
          Length = 335

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 24/61 (39%), Positives = 34/61 (55%)
 Frame = +1

Query: 277 HKLDQGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 456
           H  +   A S T T ED L++Y  +  +R  E  +  LY    + G  H+YSG+EAVAVG
Sbjct: 5   HLREDTMAKSKTNT-EDYLRMYRQMVRIRTFEDNANQLYLSAKMPGLTHMYSGEEAVAVG 63

Query: 457 M 459
           +
Sbjct: 64  I 64


>UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
           Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 353

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
 Frame = +1

Query: 304 SATLTSEDAL-KLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 456
           SA  TS D L +LY  + ++R  E A    +++  I G+ H+Y+GQEAVA G
Sbjct: 19  SAVATSPDRLAELYGKMVLIRAFEDACQRAFRQGKIGGYLHVYTGQEAVATG 70


>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
           subunit alpha; n=52; cellular organisms|Rep: Pyruvate
           dehydrogenase E1 component subunit alpha - Porphyra
           yezoensis
          Length = 346

 Score = 42.7 bits (96), Expect = 0.004
 Identities = 20/54 (37%), Positives = 30/54 (55%)
 Frame = +1

Query: 298 ATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           +T   L   + L LYE + + R  E     +Y +  + GF HLY+GQEAV+ G+
Sbjct: 16  STGLNLNKSNLLVLYEDMLLGRNFEDMCAQMYYKGKMFGFVHLYNGQEAVSTGV 69


>UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, alpha
           subunit; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate
           dehydrogenase E1 component, alpha subunit - Salinibacter
           ruber (strain DSM 13855)
          Length = 470

 Score = 42.3 bits (95), Expect = 0.005
 Identities = 21/67 (31%), Positives = 32/67 (47%)
 Frame = +1

Query: 256 EIKPYKLHKLDQGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSG 435
           E   Y+ +  D        +  ++ L L   + + RR E     +Y+ + I GF HLY G
Sbjct: 126 ETVTYETYPADTYGHDELGIADDEVLDLLRNMLLQRRFENRCRQMYQRQKISGFLHLYIG 185

Query: 436 QEAVAVG 456
           QEAV+ G
Sbjct: 186 QEAVSTG 192


>UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa sp.
           PS|Rep: Pyruvate dehydrogenase - Beggiatoa sp. PS
          Length = 331

 Score = 41.5 bits (93), Expect = 0.009
 Identities = 21/46 (45%), Positives = 28/46 (60%)
 Frame = +1

Query: 322 EDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           E+ L  Y  L ++RR+E A    Y E+ +R   HL  GQEAVAVG+
Sbjct: 14  EELLTFYRSLLLIRRVEEAIAERYTEQEMRCPTHLCIGQEAVAVGV 59


>UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
           n=2; Antonospora locustae|Rep: Pyruvate dehydrogenase E1
           alpha subunit - Antonospora locustae (Nosema locustae)
          Length = 342

 Score = 41.5 bits (93), Expect = 0.009
 Identities = 18/48 (37%), Positives = 27/48 (56%)
 Frame = +1

Query: 304 SATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 447
           S  +  +D  KLY  +  +R ++ +   +Y   +IRGFCHL  GQE V
Sbjct: 21  SCKIRYDDVEKLYRKMLCMRYMDESISKMYSRGLIRGFCHLDIGQEEV 68


>UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3;
           Proteobacteria|Rep: Dehydrogenase, E1 component -
           Sphingomonas wittichii RW1
          Length = 334

 Score = 41.1 bits (92), Expect = 0.012
 Identities = 20/59 (33%), Positives = 31/59 (52%)
 Frame = +1

Query: 289 QGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           +G A      + + ++LY  +  +R  E + G L+    I GF HL  GQE V+VG+ A
Sbjct: 10  RGAAHGRNARAPELIELYRRMVTIREAEKSCGALFAAGEIPGFIHLSDGQEGVSVGVMA 68


>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
           Pyruvate dehydrogenase - Acidothermus cellulolyticus
           (strain ATCC 43068 / 11B)
          Length = 375

 Score = 40.3 bits (90), Expect = 0.020
 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
 Frame = +1

Query: 295 PATSATLTSEDALKLY-EXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           PA        D L+ Y   + ++RR E  +  +Y+   I G+CHL  G+EA  VG+
Sbjct: 29  PADRLAQEPPDKLRAYYRMMQLIRRFEERAAEMYQRAKIGGYCHLNLGEEATVVGL 84


>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
           (class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
           RS-1
          Length = 350

 Score = 39.5 bits (88), Expect = 0.035
 Identities = 18/48 (37%), Positives = 25/48 (52%)
 Frame = +1

Query: 313 LTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 456
           L +   +  Y  + ++RR E     +Y    I GF HLY G+EA AVG
Sbjct: 21  LDAATLIDYYRQMVLIRRFEEKCQEMYTRAKIGGFLHLYIGEEATAVG 68


>UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA
           SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: PYRUVATE
           DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT -
           Encephalitozoon cuniculi
          Length = 349

 Score = 39.1 bits (87), Expect = 0.047
 Identities = 17/42 (40%), Positives = 26/42 (61%)
 Frame = +1

Query: 322 EDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 447
           + A+ +Y+ +  +R ++ A    YK K IRGFCHL  GQE +
Sbjct: 37  DKAVYIYKQMMRMRCMDEAMDREYKRKNIRGFCHLSIGQEGI 78


>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
           cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
           Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
          Length = 342

 Score = 38.7 bits (86), Expect = 0.062
 Identities = 21/61 (34%), Positives = 34/61 (55%)
 Frame = +1

Query: 283 LDQGPATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 462
           L + P  +A +   + L L+E +  LR  E  + +L+ + +++G  HL  GQEAVA G  
Sbjct: 9   LPERPTFTAEVNGRE-LDLFELMVRLRFFERRAHDLFLQGLVKGTSHLSLGQEAVATGFA 67

Query: 463 A 465
           A
Sbjct: 68  A 68


>UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|Rep:
           Pyruvate dehydrogenase - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 332

 Score = 38.3 bits (85), Expect = 0.081
 Identities = 19/48 (39%), Positives = 26/48 (54%)
 Frame = +1

Query: 313 LTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 456
           L  E  + +   +  +RR E     L+K   + GF HLY G+EAVAVG
Sbjct: 2   LGEEKLVGMLRLMLRIRRFEEKLAELFKRGKLPGFVHLYIGEEAVAVG 49


>UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent)
           alpha chain; n=1; marine actinobacterium PHSC20C1|Rep:
           Acetoin dehydrogenase (TPP-dependent) alpha chain -
           marine actinobacterium PHSC20C1
          Length = 327

 Score = 37.5 bits (83), Expect = 0.14
 Identities = 18/45 (40%), Positives = 26/45 (57%)
 Frame = +1

Query: 325 DALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           DAL+L   +  +R  E     L+ + ++RG  HL  GQEAV VG+
Sbjct: 17  DALELLRSMYEIRFFEDEIMGLFSQNLVRGSTHLCQGQEAVTVGV 61


>UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha
           subunit; n=1; Burkholderia xenovorans LB400|Rep:
           Putative 2-oxo acid dehydrogenase alpha subunit -
           Burkholderia xenovorans (strain LB400)
          Length = 334

 Score = 37.1 bits (82), Expect = 0.19
 Identities = 14/43 (32%), Positives = 26/43 (60%)
 Frame = +1

Query: 331 LKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           + +Y  + ++R +E +   L+ +  + GF HL  GQEAV+ G+
Sbjct: 20  IDIYRTMVLVREVELSLSRLFADSEVPGFIHLSLGQEAVSAGV 62


>UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E1
           component alpha-subunit, putative; n=22; Bacteria|Rep:
           Pyruvate dehydrogenase, TPP-dependent E1 component
           alpha-subunit, putative - Streptococcus sanguinis
           (strain SK36)
          Length = 357

 Score = 37.1 bits (82), Expect = 0.19
 Identities = 17/51 (33%), Positives = 29/51 (56%)
 Frame = +1

Query: 313 LTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           ++ E A  +Y+ +  +R  E  +   +    I GF HLY+G+EA+A G+ A
Sbjct: 39  VSKEKAKTMYKTMWDIRNFEENTRRFFAAGQIPGFVHLYAGEEAIATGVCA 89


>UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8;
           Chlamydiaceae|Rep: Pyruvate Dehydrogenase Alpha -
           Chlamydia pneumoniae (Chlamydophila pneumoniae)
          Length = 342

 Score = 36.7 bits (81), Expect = 0.25
 Identities = 15/40 (37%), Positives = 23/40 (57%)
 Frame = +1

Query: 331 LKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVA 450
           +K  + + ++R  E      Y E ++ GF H Y+GQEAVA
Sbjct: 32  IKFLKQMVLIREFEARGEEAYLEGLVGGFYHSYAGQEAVA 71


>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
           subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
           dehydrogenase E1 alpha subunit - Toxoplasma gondii
          Length = 635

 Score = 36.3 bits (80), Expect = 0.33
 Identities = 18/41 (43%), Positives = 23/41 (56%)
 Frame = +1

Query: 337 LYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           L E +   R +E A   LY      GF HLY+GQEAV+ G+
Sbjct: 261 LLEDMLTGRMVEDACARLYYMGKTAGFVHLYTGQEAVSAGV 301


>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
           Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
           sp. (strain CCS1)
          Length = 675

 Score = 35.9 bits (79), Expect = 0.43
 Identities = 18/53 (33%), Positives = 28/53 (52%)
 Frame = +1

Query: 298 ATSATLTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 456
           AT   L  +D     + +  +RR ET +  L+ + +I+G  H   GQEA+A G
Sbjct: 13  ATPNGLAPKDLRAALKMMLRIRRFETRAKELFLQGVIKGTAHSSVGQEAIAAG 65


>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
           n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
           component beta - Ostreococcus tauri
          Length = 835

 Score = 35.5 bits (78), Expect = 0.57
 Identities = 17/45 (37%), Positives = 23/45 (51%)
 Frame = +1

Query: 313 LTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 447
           L+ ED  K Y  + + R  E      Y    IRGF HL +GQE++
Sbjct: 132 LSDEDLSKAYYMMQLCRDFENECNQAYMAGKIRGFMHLDNGQESI 176


>UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3;
           Actinomycetales|Rep: Dehydrogenase, E1 component -
           Salinispora tropica CNB-440
          Length = 323

 Score = 34.7 bits (76), Expect = 1.0
 Identities = 17/51 (33%), Positives = 28/51 (54%)
 Frame = +1

Query: 313 LTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           +T   +++LY  + ++RR E  +  L +   I G  H Y GQE +A G+ A
Sbjct: 1   MTEVGSVRLYRTVRLIRRFEERAIELVRSGHIVGGIHPYVGQEGIAAGVCA 51


>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
           SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
           DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
          Length = 725

 Score = 34.3 bits (75), Expect = 1.3
 Identities = 17/44 (38%), Positives = 23/44 (52%)
 Frame = +1

Query: 325 DALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 456
           D LK Y  + ++RR E    +  K  ++ G  H   GQEA AVG
Sbjct: 30  DLLKWYSQMKLIRRFEEKILDFEKAGLVHGPAHASIGQEAAAVG 73


>UniRef50_A2FVJ6 Cluster: DnaK protein; n=1; Trichomonas vaginalis
           G3|Rep: DnaK protein - Trichomonas vaginalis G3
          Length = 726

 Score = 33.9 bits (74), Expect = 1.8
 Identities = 23/63 (36%), Positives = 34/63 (53%)
 Frame = +1

Query: 133 DKMSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSAT 312
           D   K + +A K LAG  +TK+     A + +Y+  K  TF  KP  +  +D G A+S T
Sbjct: 161 DSQKKKVSAAIK-LAGLKLTKIIDEKTALSLQYAIDKHDTFVSKPKYVAIIDFG-ASSLT 218

Query: 313 LTS 321
           L+S
Sbjct: 219 LSS 221


>UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit
           (Lipoamide); n=2; Sulfolobaceae|Rep: Pyruvate
           dehydrogenase, alpha subunit (Lipoamide) - Sulfolobus
           solfataricus
          Length = 345

 Score = 33.9 bits (74), Expect = 1.8
 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 9/60 (15%)
 Frame = +1

Query: 304 SATLTSEDALKLYEXLTILRRIETASGNLYKEKI---------IRGFCHLYSGQEAVAVG 456
           +A L + D L +Y+ + I+R  E +   +Y E           IRG  HL  GQEAVAVG
Sbjct: 18  NAGLKASDLLNMYKRMLIIRYFEESIRKIYHEGKNPFNMASGRIRGEMHLSIGQEAVAVG 77


>UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1;
           Chloroflexus aurantiacus J-10-fl|Rep: Dehydrogenase, E1
           component - Chloroflexus aurantiacus J-10-fl
          Length = 334

 Score = 33.1 bits (72), Expect = 3.1
 Identities = 15/39 (38%), Positives = 22/39 (56%)
 Frame = +1

Query: 349 LTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRA 465
           + I+R  E  +  L+   ++ G  HL  GQEAVA+G  A
Sbjct: 34  MQIIRAFEEKAEELFARGLVHGTMHLSIGQEAVAIGASA 72


>UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1;
           Prochlorococcus marinus subsp. pastoris str.
           CCMP1986|Rep: Dehydrogenase, E1 component -
           Prochlorococcus marinus subsp. pastoris (strain CCMP
           1378 / MED4)
          Length = 324

 Score = 32.3 bits (70), Expect = 5.4
 Identities = 15/34 (44%), Positives = 22/34 (64%)
 Frame = +1

Query: 358 LRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           +R IE A  +L K+  +RG  H Y G+EA+A G+
Sbjct: 41  IRAIEEAIVSLAKDNKLRGPIHSYVGEEAIATGV 74


>UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol
           oxidoreductase subunit alpha; n=58; cellular
           organisms|Rep: Acetoin:2,6-dichlorophenolindophenol
           oxidoreductase subunit alpha - Ralstonia eutropha
           (strain ATCC 17699 / H16 / DSM 428 / Stanier
           337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
           428 / Stanier337))
          Length = 333

 Score = 32.3 bits (70), Expect = 5.4
 Identities = 17/49 (34%), Positives = 24/49 (48%)
 Frame = +1

Query: 313 LTSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           L  E  L +Y  +  +R  E      +    I GF HLY+G+EA  VG+
Sbjct: 14  LDKETLLTVYRKMRTIRDFEERLHVDFGRGDIPGFVHLYAGEEAAGVGI 62


>UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway
           signal; n=2; Proteobacteria|Rep: Twin-arginine
           translocation pathway signal - Mesorhizobium sp. (strain
           BNC1)
          Length = 375

 Score = 31.9 bits (69), Expect = 7.1
 Identities = 16/50 (32%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
 Frame = +1

Query: 313 LTSEDALKLYEXLTILRRIE-TASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           L+ +  + ++  +  +R  E T +  +  +   RG+ H Y+GQEAVAVG+
Sbjct: 26  LSDQQLVDMFTTILRIRWHERTMADKMLTDPNYRGYNHFYAGQEAVAVGV 75


>UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent)
           alpha chain; n=6; Bacteria|Rep: Acetoin dehydrogenase
           (TPP-dependent) alpha chain - Rhizobium loti
           (Mesorhizobium loti)
          Length = 342

 Score = 31.5 bits (68), Expect = 9.4
 Identities = 15/48 (31%), Positives = 26/48 (54%)
 Frame = +1

Query: 316 TSEDALKLYEXLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 459
           ++E   ++   + ++RR E  +   Y   +I G  HL  GQEA A+G+
Sbjct: 23  SAEQLREVLYKMYLIRRFEEGAEESYMRGLIHGTMHLSIGQEASAMGI 70


>UniRef50_A5CYF4 Cluster: Putative uncharacterized protein; n=1;
           Pelotomaculum thermopropionicum SI|Rep: Putative
           uncharacterized protein - Pelotomaculum
           thermopropionicum SI
          Length = 745

 Score = 31.5 bits (68), Expect = 9.4
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)
 Frame = +1

Query: 112 GFIEIIIDKMSKLIPSAAKFLAGNTITKVTAPVVAT-NAKYSTKKEATFEIKPYKLHKLD 288
           G IE+ ID     IP+  K + G  ++ VTA   A  + K   + +   +I   +L K  
Sbjct: 411 GDIEMEIDGSKAGIPAGTKLVVGKAVSLVTASASAVKDVKIGVQGQEIGDITITELVKEA 470

Query: 289 QGPATSATLTSEDALKLYEXL--TILRRIETASGNL 390
                + T+     L L E +  T   ++E A GNL
Sbjct: 471 ISDTPNGTINHNVTLTLPEGVWFTSKPKVEVAEGNL 506


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 422,283,472
Number of Sequences: 1657284
Number of extensions: 7202585
Number of successful extensions: 17429
Number of sequences better than 10.0: 55
Number of HSP's better than 10.0 without gapping: 17035
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 17422
length of database: 575,637,011
effective HSP length: 94
effective length of database: 419,852,315
effective search space used: 25191138900
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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