Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP04_F_H04
(879 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y08685-1|CAA69941.1| 473|Homo sapiens serine palmitoyltransfera... 282 1e-75
BC068537-1|AAH68537.1| 513|Homo sapiens SPTLC1 protein protein. 282 1e-75
AL391219-2|CAH70209.1| 473|Homo sapiens serine palmitoyltransfe... 282 1e-75
AL354751-7|CAH69924.1| 473|Homo sapiens serine palmitoyltransfe... 282 1e-75
AF286717-1|AAK29328.1| 473|Homo sapiens serine palmitoyltransfe... 282 1e-75
AB209757-1|BAD92994.1| 262|Homo sapiens serine palmitoyltransfe... 129 1e-29
Y08686-1|CAA69942.1| 562|Homo sapiens serine palmitoyltransfera... 117 5e-26
BC005123-1|AAH05123.1| 562|Homo sapiens serine palmitoyltransfe... 117 5e-26
AF111168-5|AAD09621.1| 562|Homo sapiens serine palmitoyl transf... 117 5e-26
AB011098-1|BAA25452.2| 609|Homo sapiens KIAA0526 protein protein. 117 5e-26
AL445589-1|CAM16427.1| 552|Homo sapiens serine palmitoyltransfe... 115 3e-25
AL133331-1|CAM13116.1| 552|Homo sapiens serine palmitoyltransfe... 115 3e-25
AL109983-2|CAM28300.1| 552|Homo sapiens serine palmitoyltransfe... 115 3e-25
AL050320-2|CAM27358.1| 552|Homo sapiens serine palmitoyltransfe... 115 3e-25
U15555-1|AAC50871.1| 411|Homo sapiens serine palmitoyltransfera... 113 8e-25
X56351-1|CAA39794.1| 640|Homo sapiens delta- aminolevulinate sy... 81 7e-15
BC011798-1|AAH11798.1| 640|Homo sapiens aminolevulinate, delta-... 81 7e-15
AY260745-1|AAP94018.1| 640|Homo sapiens migration-inducing prot... 81 7e-15
AB063322-1|BAB93514.1| 640|Homo sapiens aminolevulinate delta-s... 81 7e-15
X60364-1|CAA42916.1| 587|Homo sapiens 5-aminolevulinate synthas... 79 2e-14
X56352-1|CAA39795.1| 582|Homo sapiens delta-aminolevulinate syn... 79 2e-14
BC030230-1|AAH30230.2| 574|Homo sapiens aminolevulinate, delta-... 79 2e-14
AL020991-2|CAA15886.1| 587|Homo sapiens aminolevulinate, delta-... 79 2e-14
AL020991-1|CAI43125.1| 550|Homo sapiens aminolevulinate, delta-... 79 2e-14
AF068624-1|AAC39838.1| 587|Homo sapiens 5-aminolevulinate synth... 79 2e-14
Z97630-2|CAB42830.1| 419|Homo sapiens glycine C-acetyltransfera... 77 6e-14
BC014457-1|AAH14457.1| 419|Homo sapiens glycine C-acetyltransfe... 77 6e-14
AF077740-1|AAC27720.1| 419|Homo sapiens 2-amino-3-ketobutyrate-... 77 6e-14
Y00451-1|CAA68506.1| 642|Homo sapiens protein ( Human mRNA for ... 74 8e-13
BC012180-1|AAH12180.1| 621|Homo sapiens KIAA1279 protein. 33 1.4
AL359844-4|CAH72378.1| 621|Homo sapiens KIAA1279 protein. 33 1.4
AK123190-1|BAC85552.1| 248|Homo sapiens .1.29). protein. 33 1.4
AB033105-1|BAA86593.1| 632|Homo sapiens KIAA1279 protein protein. 33 1.4
>Y08685-1|CAA69941.1| 473|Homo sapiens serine palmitoyltransferase,
subunit I protein.
Length = 473
Score = 282 bits (692), Expect = 1e-75
Identities = 139/270 (51%), Positives = 185/270 (68%), Gaps = 5/270 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKF++ EE +YSYGF+TIASAIP+Y+KR DIVFVD FAIQKGL ASRS I FKHN
Sbjct: 153 AKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHN 212
Query: 265 DMNDLERQLLEASEKKELNSRR----RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRII 432
DM DLER L E + + N R+ R F++VE +Y+NTG +CPL V+L K+K RI
Sbjct: 213 DMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIF 272
Query: 433 LDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSG 612
L+ESLS GVLG+HGRG+TE+ I D+IDLI ++E++ A+IGGFC G F+++HQRLSG
Sbjct: 273 LEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSG 332
Query: 613 LGYCFSASLPPMLTQAAISALDILEEKPSIIEELNDRSKMMNKALAKLDHYRYSGDEISP 792
GYCFSASLPP+L AAI AL+I+EE P I L ++ ++KAL + + G+ +SP
Sbjct: 333 QGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQIHKALQGISGLKVVGESLSP 392
Query: 793 IKHVYLKDDLTDRLKH-SYLRNIAAYCFEK 879
H+ L++ R + L+ I C +
Sbjct: 393 AFHLQLEESTGSREQDVRLLQEIVDQCMNR 422
>BC068537-1|AAH68537.1| 513|Homo sapiens SPTLC1 protein protein.
Length = 513
Score = 282 bits (692), Expect = 1e-75
Identities = 139/270 (51%), Positives = 185/270 (68%), Gaps = 5/270 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKF++ EE +YSYGF+TIASAIP+Y+KR DIVFVD FAIQKGL ASRS I FKHN
Sbjct: 153 AKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHN 212
Query: 265 DMNDLERQLLEASEKKELNSRR----RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRII 432
DM DLER L E + + N R+ R F++VE +Y+NTG +CPL V+L K+K RI
Sbjct: 213 DMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIF 272
Query: 433 LDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSG 612
L+ESLS GVLG+HGRG+TE+ I D+IDLI ++E++ A+IGGFC G F+++HQRLSG
Sbjct: 273 LEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSG 332
Query: 613 LGYCFSASLPPMLTQAAISALDILEEKPSIIEELNDRSKMMNKALAKLDHYRYSGDEISP 792
GYCFSASLPP+L AAI AL+I+EE P I L ++ ++KAL + + G+ +SP
Sbjct: 333 QGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQIHKALQGISGLKVVGESLSP 392
Query: 793 IKHVYLKDDLTDRLKH-SYLRNIAAYCFEK 879
H+ L++ R + L+ I C +
Sbjct: 393 AFHLQLEESTGSREQDVRLLQEIVDQCMNR 422
>AL391219-2|CAH70209.1| 473|Homo sapiens serine
palmitoyltransferase, long chain base subunit 1 protein.
Length = 473
Score = 282 bits (692), Expect = 1e-75
Identities = 139/270 (51%), Positives = 185/270 (68%), Gaps = 5/270 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKF++ EE +YSYGF+TIASAIP+Y+KR DIVFVD FAIQKGL ASRS I FKHN
Sbjct: 153 AKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHN 212
Query: 265 DMNDLERQLLEASEKKELNSRR----RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRII 432
DM DLER L E + + N R+ R F++VE +Y+NTG +CPL V+L K+K RI
Sbjct: 213 DMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIF 272
Query: 433 LDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSG 612
L+ESLS GVLG+HGRG+TE+ I D+IDLI ++E++ A+IGGFC G F+++HQRLSG
Sbjct: 273 LEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSG 332
Query: 613 LGYCFSASLPPMLTQAAISALDILEEKPSIIEELNDRSKMMNKALAKLDHYRYSGDEISP 792
GYCFSASLPP+L AAI AL+I+EE P I L ++ ++KAL + + G+ +SP
Sbjct: 333 QGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQIHKALQGISGLKVVGESLSP 392
Query: 793 IKHVYLKDDLTDRLKH-SYLRNIAAYCFEK 879
H+ L++ R + L+ I C +
Sbjct: 393 AFHLQLEESTGSREQDVRLLQEIVDQCMNR 422
>AL354751-7|CAH69924.1| 473|Homo sapiens serine
palmitoyltransferase, long chain base subunit 1 protein.
Length = 473
Score = 282 bits (692), Expect = 1e-75
Identities = 139/270 (51%), Positives = 185/270 (68%), Gaps = 5/270 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKF++ EE +YSYGF+TIASAIP+Y+KR DIVFVD FAIQKGL ASRS I FKHN
Sbjct: 153 AKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHN 212
Query: 265 DMNDLERQLLEASEKKELNSRR----RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRII 432
DM DLER L E + + N R+ R F++VE +Y+NTG +CPL V+L K+K RI
Sbjct: 213 DMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIF 272
Query: 433 LDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSG 612
L+ESLS GVLG+HGRG+TE+ I D+IDLI ++E++ A+IGGFC G F+++HQRLSG
Sbjct: 273 LEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSG 332
Query: 613 LGYCFSASLPPMLTQAAISALDILEEKPSIIEELNDRSKMMNKALAKLDHYRYSGDEISP 792
GYCFSASLPP+L AAI AL+I+EE P I L ++ ++KAL + + G+ +SP
Sbjct: 333 QGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQIHKALQGISGLKVVGESLSP 392
Query: 793 IKHVYLKDDLTDRLKH-SYLRNIAAYCFEK 879
H+ L++ R + L+ I C +
Sbjct: 393 AFHLQLEESTGSREQDVRLLQEIVDQCMNR 422
>AF286717-1|AAK29328.1| 473|Homo sapiens serine
palmitoyltransferase protein.
Length = 473
Score = 282 bits (692), Expect = 1e-75
Identities = 139/270 (51%), Positives = 185/270 (68%), Gaps = 5/270 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKF++ EE +YSYGF+TIASAIP+Y+KR DIVFVD FAIQKGL ASRS I FKHN
Sbjct: 153 AKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHN 212
Query: 265 DMNDLERQLLEASEKKELNSRR----RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRII 432
DM DLER L E + + N R+ R F++VE +Y+NTG +CPL V+L K+K RI
Sbjct: 213 DMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIF 272
Query: 433 LDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSG 612
L+ESLS GVLG+HGRG+TE+ I D+IDLI ++E++ A+IGGFC G F+++HQRLSG
Sbjct: 273 LEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSG 332
Query: 613 LGYCFSASLPPMLTQAAISALDILEEKPSIIEELNDRSKMMNKALAKLDHYRYSGDEISP 792
GYCFSASLPP+L AAI AL+I+EE P I L ++ ++KAL + + G+ +SP
Sbjct: 333 QGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCGQIHKALQGISGLKVVGESLSP 392
Query: 793 IKHVYLKDDLTDRLKH-SYLRNIAAYCFEK 879
H+ L++ R + L+ I C +
Sbjct: 393 AFHLQLEESTGSREQDVRLLQEIVDQCMNR 422
>AB209757-1|BAD92994.1| 262|Homo sapiens serine
palmitoyltransferase subunit 1 isoform a variant
protein.
Length = 262
Score = 129 bits (311), Expect = 1e-29
Identities = 64/109 (58%), Positives = 78/109 (71%), Gaps = 4/109 (3%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKF++ EE +YSYGF+TIASAIP+Y+KR DIVFVD FAIQKGL ASRS I FKHN
Sbjct: 148 AKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHN 207
Query: 265 DMNDLERQLLEASEKKELNSRR----RAFLIVEAIYLNTGKMCPLVRAV 399
DM DLER L E + + N R+ R F++VE +Y+NTG +CPL V
Sbjct: 208 DMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELV 256
>Y08686-1|CAA69942.1| 562|Homo sapiens serine palmitoyltransferase,
subunit II protein.
Length = 562
Score = 117 bits (282), Expect = 5e-26
Identities = 69/246 (28%), Positives = 129/246 (52%), Gaps = 9/246 (3%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
A+FL VE Y GF+T + IP+ + ++ DE ++ G S + I FKHN
Sbjct: 224 ARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHN 283
Query: 265 DMNDLERQLLEASEKKELNSRR---RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIIL 435
+M LE+ L +A + +RR + ++VE IY G + L + L +K+K + L
Sbjct: 284 NMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYL 343
Query: 436 DESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSGL 615
DE+ SIG LG GRG+ EY + +++D+++G+ SF GG+ G ++++ R
Sbjct: 344 DEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSH 403
Query: 616 GYCFSASLPPMLTQAAISALDIL--EEKPSI----IEELNDRSKMMNKALAKLDHYRYSG 777
++ SL P + + I+++ + ++ S+ +++L + ++ + L ++ Y G
Sbjct: 404 SAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIY-G 462
Query: 778 DEISPI 795
+E SP+
Sbjct: 463 NEDSPV 468
>BC005123-1|AAH05123.1| 562|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2 protein.
Length = 562
Score = 117 bits (282), Expect = 5e-26
Identities = 69/246 (28%), Positives = 129/246 (52%), Gaps = 9/246 (3%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
A+FL VE Y GF+T + IP+ + ++ DE ++ G S + I FKHN
Sbjct: 224 ARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHN 283
Query: 265 DMNDLERQLLEASEKKELNSRR---RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIIL 435
+M LE+ L +A + +RR + ++VE IY G + L + L +K+K + L
Sbjct: 284 NMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYL 343
Query: 436 DESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSGL 615
DE+ SIG LG GRG+ EY + +++D+++G+ SF GG+ G ++++ R
Sbjct: 344 DEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSH 403
Query: 616 GYCFSASLPPMLTQAAISALDIL--EEKPSI----IEELNDRSKMMNKALAKLDHYRYSG 777
++ SL P + + I+++ + ++ S+ +++L + ++ + L ++ Y G
Sbjct: 404 SAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIY-G 462
Query: 778 DEISPI 795
+E SP+
Sbjct: 463 NEDSPV 468
>AF111168-5|AAD09621.1| 562|Homo sapiens serine palmitoyl
transferase, subunit II protein.
Length = 562
Score = 117 bits (282), Expect = 5e-26
Identities = 69/246 (28%), Positives = 129/246 (52%), Gaps = 9/246 (3%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
A+FL VE Y GF+T + IP+ + ++ DE ++ G S + I FKHN
Sbjct: 224 ARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHN 283
Query: 265 DMNDLERQLLEASEKKELNSRR---RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIIL 435
+M LE+ L +A + +RR + ++VE IY G + L + L +K+K + L
Sbjct: 284 NMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYL 343
Query: 436 DESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSGL 615
DE+ SIG LG GRG+ EY + +++D+++G+ SF GG+ G ++++ R
Sbjct: 344 DEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSH 403
Query: 616 GYCFSASLPPMLTQAAISALDIL--EEKPSI----IEELNDRSKMMNKALAKLDHYRYSG 777
++ SL P + + I+++ + ++ S+ +++L + ++ + L ++ Y G
Sbjct: 404 SAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIY-G 462
Query: 778 DEISPI 795
+E SP+
Sbjct: 463 NEDSPV 468
>AB011098-1|BAA25452.2| 609|Homo sapiens KIAA0526 protein protein.
Length = 609
Score = 117 bits (282), Expect = 5e-26
Identities = 69/246 (28%), Positives = 129/246 (52%), Gaps = 9/246 (3%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
A+FL VE Y GF+T + IP+ + ++ DE ++ G S + I FKHN
Sbjct: 271 ARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHN 330
Query: 265 DMNDLERQLLEASEKKELNSRR---RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIIL 435
+M LE+ L +A + +RR + ++VE IY G + L + L +K+K + L
Sbjct: 331 NMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYL 390
Query: 436 DESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSGL 615
DE+ SIG LG GRG+ EY + +++D+++G+ SF GG+ G ++++ R
Sbjct: 391 DEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSH 450
Query: 616 GYCFSASLPPMLTQAAISALDIL--EEKPSI----IEELNDRSKMMNKALAKLDHYRYSG 777
++ SL P + + I+++ + ++ S+ +++L + ++ + L ++ Y G
Sbjct: 451 SAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIY-G 509
Query: 778 DEISPI 795
+E SP+
Sbjct: 510 NEDSPV 515
>AL445589-1|CAM16427.1| 552|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2-like
(aminotransferase 2 protein.
Length = 552
Score = 115 bits (276), Expect = 3e-25
Identities = 61/203 (30%), Positives = 111/203 (54%), Gaps = 3/203 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKFL VE V+ GF+T + IP+ + ++ DE ++ G S + I FKHN
Sbjct: 216 AKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHN 275
Query: 265 DMNDLERQLLEASEKKELNSRR---RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIIL 435
+ LE+ L +A + +RR + ++VE +Y G + L + + L +K+K + +
Sbjct: 276 NTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYI 335
Query: 436 DESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSGL 615
DE+ SIG +G GRG+TE+ + E+D+++G+ SF GG+ AG +V++ R+
Sbjct: 336 DEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSH 395
Query: 616 GYCFSASLPPMLTQAAISALDIL 684
+++S+ P + + I +L ++
Sbjct: 396 SAVYASSMSPPIAEQIIRSLKLI 418
>AL133331-1|CAM13116.1| 552|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2-like
(aminotransferase 2 protein.
Length = 552
Score = 115 bits (276), Expect = 3e-25
Identities = 61/203 (30%), Positives = 111/203 (54%), Gaps = 3/203 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKFL VE V+ GF+T + IP+ + ++ DE ++ G S + I FKHN
Sbjct: 216 AKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHN 275
Query: 265 DMNDLERQLLEASEKKELNSRR---RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIIL 435
+ LE+ L +A + +RR + ++VE +Y G + L + + L +K+K + +
Sbjct: 276 NTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYI 335
Query: 436 DESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSGL 615
DE+ SIG +G GRG+TE+ + E+D+++G+ SF GG+ AG +V++ R+
Sbjct: 336 DEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSH 395
Query: 616 GYCFSASLPPMLTQAAISALDIL 684
+++S+ P + + I +L ++
Sbjct: 396 SAVYASSMSPPIAEQIIRSLKLI 418
>AL109983-2|CAM28300.1| 552|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2-like
(aminotransferase 2 protein.
Length = 552
Score = 115 bits (276), Expect = 3e-25
Identities = 61/203 (30%), Positives = 111/203 (54%), Gaps = 3/203 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKFL VE V+ GF+T + IP+ + ++ DE ++ G S + I FKHN
Sbjct: 216 AKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHN 275
Query: 265 DMNDLERQLLEASEKKELNSRR---RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIIL 435
+ LE+ L +A + +RR + ++VE +Y G + L + + L +K+K + +
Sbjct: 276 NTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYI 335
Query: 436 DESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSGL 615
DE+ SIG +G GRG+TE+ + E+D+++G+ SF GG+ AG +V++ R+
Sbjct: 336 DEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSH 395
Query: 616 GYCFSASLPPMLTQAAISALDIL 684
+++S+ P + + I +L ++
Sbjct: 396 SAVYASSMSPPIAEQIIRSLKLI 418
>AL050320-2|CAM27358.1| 552|Homo sapiens serine
palmitoyltransferase, long chain base subunit 2-like
(aminotransferase 2 protein.
Length = 552
Score = 115 bits (276), Expect = 3e-25
Identities = 61/203 (30%), Positives = 111/203 (54%), Gaps = 3/203 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
AKFL VE V+ GF+T + IP+ + ++ DE ++ G S + I FKHN
Sbjct: 216 AKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHN 275
Query: 265 DMNDLERQLLEASEKKELNSRR---RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIIL 435
+ LE+ L +A + +RR + ++VE +Y G + L + + L +K+K + +
Sbjct: 276 NTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYI 335
Query: 436 DESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSGL 615
DE+ SIG +G GRG+TE+ + E+D+++G+ SF GG+ AG +V++ R+
Sbjct: 336 DEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSH 395
Query: 616 GYCFSASLPPMLTQAAISALDIL 684
+++S+ P + + I +L ++
Sbjct: 396 SAVYASSMSPPIAEQIIRSLKLI 418
>U15555-1|AAC50871.1| 411|Homo sapiens serine palmitoyltransferase
protein.
Length = 411
Score = 113 bits (272), Expect = 8e-25
Identities = 61/200 (30%), Positives = 106/200 (53%), Gaps = 3/200 (1%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
A+FL VE Y GF+T + IP+ + ++ DE ++ G S + I FKHN
Sbjct: 165 ARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHN 224
Query: 265 DMNDLERQLLEASEKKELNSRR---RAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIIL 435
+M LE+ L +A + +RR + ++VE IY G + L + L +K+K + L
Sbjct: 225 NMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYL 284
Query: 436 DESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAGTHFIVEHQRLSGL 615
DE+ SIG LG GRG+ EY + +++D+++G+ SF GG+ G ++++ R
Sbjct: 285 DEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSH 344
Query: 616 GYCFSASLPPMLTQAAISAL 675
++ SL P + + I+++
Sbjct: 345 SAVYATSLSPPVVEQIITSM 364
>X56351-1|CAA39794.1| 640|Homo sapiens delta- aminolevulinate
synthase (housekeeping) protein.
Length = 640
Score = 80.6 bits (190), Expect = 7e-15
Identities = 51/179 (28%), Positives = 95/179 (53%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ SR F+HND++ L R+LL+ S+ + E ++ G +CPL
Sbjct: 344 QGIRNSRVPKYIFRHNDVSHL-RELLQRSDPSVPK-----IVAFETVHSMDGAVCPLEEL 397
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
++A +F +DE ++G+ G G GI + + ++D+I G+L +F +GG+ A
Sbjct: 398 CDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGV-MPKMDIISGTLGKAFGCVGGYIAS 456
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILEE-KPSIIEELNDRS-KMMNKAL 747
T +++ R G+ F+ SLPPML A+ ++ IL+ + ++ + R+ K+M + L
Sbjct: 457 TSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVKLMRQML 515
>BC011798-1|AAH11798.1| 640|Homo sapiens aminolevulinate, delta-,
synthase 1 protein.
Length = 640
Score = 80.6 bits (190), Expect = 7e-15
Identities = 51/179 (28%), Positives = 95/179 (53%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ SR F+HND++ L R+LL+ S+ + E ++ G +CPL
Sbjct: 344 QGIRNSRVPKYIFRHNDVSHL-RELLQRSDPSVPK-----IVAFETVHSMDGAVCPLEEL 397
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
++A +F +DE ++G+ G G GI + + ++D+I G+L +F +GG+ A
Sbjct: 398 CDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGV-MPKMDIISGTLGKAFGCVGGYIAS 456
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILEE-KPSIIEELNDRS-KMMNKAL 747
T +++ R G+ F+ SLPPML A+ ++ IL+ + ++ + R+ K+M + L
Sbjct: 457 TSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVKLMRQML 515
>AY260745-1|AAP94018.1| 640|Homo sapiens migration-inducing protein
4 protein.
Length = 640
Score = 80.6 bits (190), Expect = 7e-15
Identities = 51/179 (28%), Positives = 95/179 (53%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ SR F+HND++ L R+LL+ S+ + E ++ G +CPL
Sbjct: 344 QGIRNSRVPKYIFRHNDVSHL-RELLQRSDPSVPK-----IVAFETVHSMDGAVCPLEEL 397
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
++A +F +DE ++G+ G G GI + + ++D+I G+L +F +GG+ A
Sbjct: 398 CDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGV-MPKMDIISGTLGKAFGCVGGYIAS 456
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILEE-KPSIIEELNDRS-KMMNKAL 747
T +++ R G+ F+ SLPPML A+ ++ IL+ + ++ + R+ K+M + L
Sbjct: 457 TSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVKLMRQML 515
>AB063322-1|BAB93514.1| 640|Homo sapiens aminolevulinate
delta-synthase 1 protein.
Length = 640
Score = 80.6 bits (190), Expect = 7e-15
Identities = 51/179 (28%), Positives = 95/179 (53%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ SR F+HND++ L R+LL+ S+ + E ++ G +CPL
Sbjct: 344 QGIRNSRVPKYIFRHNDVSHL-RELLQRSDPSVPK-----IVAFETVHSMDGAVCPLEEL 397
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
++A +F +DE ++G+ G G GI + + ++D+I G+L +F +GG+ A
Sbjct: 398 CDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGV-MPKMDIISGTLGKAFGCVGGYIAS 456
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILEE-KPSIIEELNDRS-KMMNKAL 747
T +++ R G+ F+ SLPPML A+ ++ IL+ + ++ + R+ K+M + L
Sbjct: 457 TSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVKLMRQML 515
>X60364-1|CAA42916.1| 587|Homo sapiens 5-aminolevulinate synthase
precursor protein.
Length = 587
Score = 79.4 bits (187), Expect = 2e-14
Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ S + F+HND + L++ LLE S N + + E ++ G +CPL
Sbjct: 290 QGIRNSGAAKFVFRHNDPDHLKK-LLEKS-----NPKIPKIVAFETVHSMDGAICPLEEL 343
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
+++ ++ +DE ++G+ G G GI E I +ID+I G+L +F +GG+ A
Sbjct: 344 CDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMH-KIDIISGTLGKAFGCVGGYIAS 402
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILE-EKPSIIEELNDRS-KMMNKAL 747
T +V+ R G+ F+ SLPPM+ A+ ++ +L+ E+ + + R+ K M + L
Sbjct: 403 TRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLL 461
>X56352-1|CAA39795.1| 582|Homo sapiens delta-aminolevulinate
synthase (erythroid) protein.
Length = 582
Score = 79.4 bits (187), Expect = 2e-14
Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ S + F+HND + L++ LLE S N + + E ++ G +CPL
Sbjct: 285 QGIRNSGAAKFVFRHNDPDHLKK-LLEKS-----NPKIPKIVAFETVHSMDGAICPLEEL 338
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
+++ ++ +DE ++G+ G G GI E I +ID+I G+L +F +GG+ A
Sbjct: 339 CDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMH-KIDIISGTLGKAFGCVGGYIAS 397
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILE-EKPSIIEELNDRS-KMMNKAL 747
T +V+ R G+ F+ SLPPM+ A+ ++ +L+ E+ + + R+ K M + L
Sbjct: 398 TRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLL 456
>BC030230-1|AAH30230.2| 574|Homo sapiens aminolevulinate, delta-,
synthase 2 (sideroblastic/hypochromic anemia) protein.
Length = 574
Score = 79.4 bits (187), Expect = 2e-14
Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ S + F+HND + L++ LLE S N + + E ++ G +CPL
Sbjct: 277 QGIRNSGAAKFVFRHNDPDHLKK-LLEKS-----NPKIPKIVAFETVHSMDGAICPLEEL 330
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
+++ ++ +DE ++G+ G G GI E I +ID+I G+L +F +GG+ A
Sbjct: 331 CDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMH-KIDIISGTLGKAFGCVGGYIAS 389
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILE-EKPSIIEELNDRS-KMMNKAL 747
T +V+ R G+ F+ SLPPM+ A+ ++ +L+ E+ + + R+ K M + L
Sbjct: 390 TRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLL 448
>AL020991-2|CAA15886.1| 587|Homo sapiens aminolevulinate, delta-,
synthase 2 (sideroblastic/hypochromic anemia) protein.
Length = 587
Score = 79.4 bits (187), Expect = 2e-14
Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ S + F+HND + L++ LLE S N + + E ++ G +CPL
Sbjct: 290 QGIRNSGAAKFVFRHNDPDHLKK-LLEKS-----NPKIPKIVAFETVHSMDGAICPLEEL 343
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
+++ ++ +DE ++G+ G G GI E I +ID+I G+L +F +GG+ A
Sbjct: 344 CDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMH-KIDIISGTLGKAFGCVGGYIAS 402
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILE-EKPSIIEELNDRS-KMMNKAL 747
T +V+ R G+ F+ SLPPM+ A+ ++ +L+ E+ + + R+ K M + L
Sbjct: 403 TRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLL 461
>AL020991-1|CAI43125.1| 550|Homo sapiens aminolevulinate, delta-,
synthase 2 (sideroblastic/hypochromic anemia) protein.
Length = 550
Score = 79.4 bits (187), Expect = 2e-14
Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ S + F+HND + L++ LLE S N + + E ++ G +CPL
Sbjct: 253 QGIRNSGAAKFVFRHNDPDHLKK-LLEKS-----NPKIPKIVAFETVHSMDGAICPLEEL 306
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
+++ ++ +DE ++G+ G G GI E I +ID+I G+L +F +GG+ A
Sbjct: 307 CDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMH-KIDIISGTLGKAFGCVGGYIAS 365
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILE-EKPSIIEELNDRS-KMMNKAL 747
T +V+ R G+ F+ SLPPM+ A+ ++ +L+ E+ + + R+ K M + L
Sbjct: 366 TRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLL 424
>AF068624-1|AAC39838.1| 587|Homo sapiens 5-aminolevulinate synthase
2 protein.
Length = 587
Score = 79.4 bits (187), Expect = 2e-14
Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ S + F+HND + L++ LLE S N + + E ++ G +CPL
Sbjct: 290 QGIRNSGAAKFVFRHNDPDHLKK-LLEKS-----NPKIPKIVAFETVHSMDGAICPLEEL 343
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
+++ ++ +DE ++G+ G G GI E I +ID+I G+L +F +GG+ A
Sbjct: 344 CDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMH-KIDIISGTLGKAFGCVGGYIAS 402
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILE-EKPSIIEELNDRS-KMMNKAL 747
T +V+ R G+ F+ SLPPM+ A+ ++ +L+ E+ + + R+ K M + L
Sbjct: 403 TRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLL 461
>Z97630-2|CAB42830.1| 419|Homo sapiens glycine C-acetyltransferase
(2-amino-3-ketobutyrate coenzyme A ligase) protein.
Length = 419
Score = 77.4 bits (182), Expect = 6e-14
Identities = 57/211 (27%), Positives = 95/211 (45%), Gaps = 1/211 (0%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
A+F + E+ +Y + A + +D V DE +I G+ ++ ++H
Sbjct: 120 ARFHQREDAILYPSCYDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHL 179
Query: 265 DMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIILDES 444
DM DLE +L EA + R + + + G + PL LA ++ + +DE
Sbjct: 180 DMADLEAKLQEAQK------HRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDEC 233
Query: 445 LSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFA-TIGGFCAGTHFIVEHQRLSGLGY 621
+ G LG GRG E L + D++ +I +L + GG+ G +V R Y
Sbjct: 234 HATGFLGPTGRGTDELLGV-MDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPY 292
Query: 622 CFSASLPPMLTQAAISALDILEEKPSIIEEL 714
FS SLPP + A ALD+L +I++ +
Sbjct: 293 LFSNSLPPAVVGCASKALDLLMGSNTIVQSM 323
>BC014457-1|AAH14457.1| 419|Homo sapiens glycine
C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A
ligase) protein.
Length = 419
Score = 77.4 bits (182), Expect = 6e-14
Identities = 57/211 (27%), Positives = 95/211 (45%), Gaps = 1/211 (0%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
A+F + E+ +Y + A + +D V DE +I G+ ++ ++H
Sbjct: 120 ARFHQREDAILYPSCYDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHL 179
Query: 265 DMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIILDES 444
DM DLE +L EA + R + + + G + PL LA ++ + +DE
Sbjct: 180 DMADLEAKLQEAQK------HRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDEC 233
Query: 445 LSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFA-TIGGFCAGTHFIVEHQRLSGLGY 621
+ G LG GRG E L + D++ +I +L + GG+ G +V R Y
Sbjct: 234 HATGFLGPTGRGTDELLGV-MDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPY 292
Query: 622 CFSASLPPMLTQAAISALDILEEKPSIIEEL 714
FS SLPP + A ALD+L +I++ +
Sbjct: 293 LFSNSLPPAVVGCASKALDLLMGSNTIVQSM 323
>AF077740-1|AAC27720.1| 419|Homo sapiens 2-amino-3-ketobutyrate-CoA
ligase protein.
Length = 419
Score = 77.4 bits (182), Expect = 6e-14
Identities = 57/211 (27%), Positives = 95/211 (45%), Gaps = 1/211 (0%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
A+F + E+ +Y + A + +D V DE +I G+ ++ ++H
Sbjct: 120 ARFHQREDAILYPSCYDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHL 179
Query: 265 DMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIILDES 444
DM DLE +L EA + R + + + G + PL LA ++ + +DE
Sbjct: 180 DMADLEAKLQEAQK------HRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDEC 233
Query: 445 LSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFA-TIGGFCAGTHFIVEHQRLSGLGY 621
+ G LG GRG E L + D++ +I +L + GG+ G +V R Y
Sbjct: 234 HATGFLGPTGRGTDELLGV-MDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPY 292
Query: 622 CFSASLPPMLTQAAISALDILEEKPSIIEEL 714
FS SLPP + A ALD+L +I++ +
Sbjct: 293 LFSNSLPPAVVGCASKALDLLMGSNTIVQSM 323
>Y00451-1|CAA68506.1| 642|Homo sapiens protein ( Human mRNA for
5-aminolevulinate synthase. ).
Length = 642
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/179 (27%), Positives = 93/179 (51%), Gaps = 2/179 (1%)
Frame = +1
Query: 217 KGLDASRSKICYFKHNDMNDLERQLLEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRA 396
+G+ SR F+HND++ L R+LL+ S+ + E ++ G + PL
Sbjct: 346 QGIRNSRVPKYIFRHNDVSHL-RELLQRSDPSVPK-----IVAFETVHSVDGAVLPLEEL 399
Query: 397 VELARKFKLRIILDESLSIGVLGKHGRGITEYLNIPRDEIDLIVGSLEHSFATIGGFCAG 576
++A +F +DE + G+ G G GI + + ++D+I G+L +F +GG+ A
Sbjct: 400 CDVAHEFGAITFVDEVHAWGLYGARGGGIGDRDGV-MPKMDIISGTLGKAFGCVGGYIAS 458
Query: 577 THFIVEHQRLSGLGYCFSASLPPMLTQAAISALDILEE-KPSIIEELNDRS-KMMNKAL 747
T +++ R G+ F+ SLPPML A+ ++ IL+ + ++ + R+ K+M + L
Sbjct: 459 TRSLMDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVVRRQHQRNVKLMRQML 517
>BC012180-1|AAH12180.1| 621|Homo sapiens KIAA1279 protein.
Length = 621
Score = 33.1 bits (72), Expect = 1.4
Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +1
Query: 274 DLERQL-LEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIILDESLS 450
DL++Q L A KKEL+ + +A+ TG++C + AVE + + +E+
Sbjct: 337 DLDKQSELRALRKKELDEEES--IRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARE 394
Query: 451 IGVLGKH 471
+ +LG+H
Sbjct: 395 LFLLGQH 401
>AL359844-4|CAH72378.1| 621|Homo sapiens KIAA1279 protein.
Length = 621
Score = 33.1 bits (72), Expect = 1.4
Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +1
Query: 274 DLERQL-LEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIILDESLS 450
DL++Q L A KKEL+ + +A+ TG++C + AVE + + +E+
Sbjct: 337 DLDKQSELRALRKKELDEEES--IRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARE 394
Query: 451 IGVLGKH 471
+ +LG+H
Sbjct: 395 LFLLGQH 401
>AK123190-1|BAC85552.1| 248|Homo sapiens .1.29). protein.
Length = 248
Score = 33.1 bits (72), Expect = 1.4
Identities = 20/76 (26%), Positives = 36/76 (47%)
Frame = +1
Query: 85 AKFLEVEETCVYSYGFSTIASAIPSYAKRKDIVFVDECVWFAIQKGLDASRSKICYFKHN 264
A+F + E+ +Y + A + +D V DE +I G+ ++ ++H
Sbjct: 146 ARFHQREDAILYPSCYDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHL 205
Query: 265 DMNDLERQLLEASEKK 312
DM DLE +L EA + +
Sbjct: 206 DMADLEAKLQEAQKHR 221
>AB033105-1|BAA86593.1| 632|Homo sapiens KIAA1279 protein protein.
Length = 632
Score = 33.1 bits (72), Expect = 1.4
Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +1
Query: 274 DLERQL-LEASEKKELNSRRRAFLIVEAIYLNTGKMCPLVRAVELARKFKLRIILDESLS 450
DL++Q L A KKEL+ + +A+ TG++C + AVE + + +E+
Sbjct: 348 DLDKQSELRALRKKELDEEES--IRKKAVQFGTGELCDAISAVEEKVSYLRPLDFEEARE 405
Query: 451 IGVLGKH 471
+ +LG+H
Sbjct: 406 LFLLGQH 412
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,815,349
Number of Sequences: 237096
Number of extensions: 2379446
Number of successful extensions: 4342
Number of sequences better than 10.0: 33
Number of HSP's better than 10.0 without gapping: 4116
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4303
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11215125244
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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