Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fdpeP04_F_E06
(887 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 156 1e-37
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 155 2e-37
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 155 2e-37
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 155 2e-37
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 155 2e-37
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 155 2e-37
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 155 2e-37
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 155 2e-37
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 155 2e-37
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 155 2e-37
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 155 2e-37
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 155 2e-37
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 154 4e-37
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 154 5e-37
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 149 1e-35
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 147 5e-35
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 147 5e-35
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 147 5e-35
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 147 5e-35
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 147 5e-35
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 147 5e-35
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 147 5e-35
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 146 9e-35
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 146 1e-34
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 145 2e-34
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 144 5e-34
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 144 5e-34
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 144 5e-34
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 144 5e-34
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 144 5e-34
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 144 5e-34
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 144 5e-34
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 144 5e-34
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 144 5e-34
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 144 5e-34
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 144 5e-34
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 143 9e-34
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 142 1e-33
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 142 1e-33
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 142 1e-33
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 142 1e-33
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 142 1e-33
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 142 1e-33
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 142 2e-33
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 142 2e-33
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 142 2e-33
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 142 2e-33
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 142 2e-33
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 142 2e-33
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 142 2e-33
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 142 2e-33
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 142 2e-33
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 142 2e-33
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 142 2e-33
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 140 8e-33
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 140 8e-33
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 140 8e-33
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 140 8e-33
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 140 8e-33
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 140 8e-33
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 140 8e-33
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 140 8e-33
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 139 1e-32
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 136 1e-31
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 136 1e-31
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 136 1e-31
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 136 1e-31
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 136 1e-31
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 134 3e-31
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 134 4e-31
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 134 4e-31
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 134 4e-31
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 134 4e-31
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 134 4e-31
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 134 5e-31
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 132 2e-30
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 127 6e-29
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 121 3e-27
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 121 3e-27
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 121 3e-27
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 121 3e-27
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 120 7e-27
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 120 7e-27
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 114 4e-25
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 114 4e-25
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 114 4e-25
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 110 8e-24
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 109 1e-23
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 109 2e-23
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 100 2e-22
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 42 0.002
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 36 0.26
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 33 1.0
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 156 bits (378), Expect = 1e-37
Identities = 75/163 (46%), Positives = 107/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P+ K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 155 bits (376), Expect = 2e-37
Identities = 75/163 (46%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 2 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 61
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 62 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 121
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 122 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 164
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 154 bits (374), Expect = 4e-37
Identities = 74/161 (45%), Positives = 105/161 (65%), Gaps = 1/161 (0%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+ +
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 551 TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP-K 727
V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 728 ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 154 bits (373), Expect = 5e-37
Identities = 74/163 (45%), Positives = 106/163 (65%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P + G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D W ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 149 bits (362), Expect = 1e-35
Identities = 74/163 (45%), Positives = 105/163 (64%), Gaps = 1/163 (0%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKID 544
L L +G MP++ LGT PP TE V+ AID+GYR ID A++Y NE +G AI+ K+
Sbjct: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64
Query: 545 DGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIP 724
+ V+R+ELFI+ KLW T+H LV+ AC+ +L+DL L++ DL+LIH P K G P
Sbjct: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124
Query: 725 -KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S + S+ + +D ME+LV +GL K+IG+SNFN Q+
Sbjct: 125 LDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQV 167
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 147 bits (356), Expect = 5e-35
Identities = 77/166 (46%), Positives = 104/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 69
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 70 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 129
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 130 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 175
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 147 bits (356), Expect = 5e-35
Identities = 77/166 (46%), Positives = 104/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 147 bits (356), Expect = 5e-35
Identities = 77/166 (46%), Positives = 104/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 147 bits (356), Expect = 5e-35
Identities = 77/166 (46%), Positives = 104/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 147 bits (356), Expect = 5e-35
Identities = 77/166 (46%), Positives = 104/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 147 bits (356), Expect = 5e-35
Identities = 77/166 (46%), Positives = 104/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 147 bits (356), Expect = 5e-35
Identities = 77/166 (46%), Positives = 104/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 146 bits (354), Expect = 9e-35
Identities = 77/166 (46%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 146 bits (353), Expect = 1e-34
Identities = 77/166 (46%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V R+++F KLWSTFHR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 145 bits (351), Expect = 2e-34
Identities = 76/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ GY ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 21 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 80
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 81 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 140
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 141 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 182
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 144 bits (348), Expect = 5e-34
Identities = 75/162 (46%), Positives = 102/162 (62%), Gaps = 4/162 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E V+ AI+ G+ ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWS HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFN 838
IPK + I + D W ME GLAKSIGVSNFN
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFN 169
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 143 bits (346), Expect = 9e-34
Identities = 76/166 (45%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PRLTT-EIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT P PR E+ + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLWST HR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 142 bits (345), Expect = 1e-33
Identities = 73/166 (43%), Positives = 105/166 (63%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+PK + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 142 bits (345), Expect = 1e-33
Identities = 73/166 (43%), Positives = 105/166 (63%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 65
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 125
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+PK + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 126 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 171
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 142 bits (345), Expect = 1e-33
Identities = 73/166 (43%), Positives = 105/166 (63%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+PK + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 142 bits (345), Expect = 1e-33
Identities = 73/166 (43%), Positives = 105/166 (63%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+PK + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 PLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 142 bits (345), Expect = 1e-33
Identities = 73/166 (43%), Positives = 105/166 (63%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+PK + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 142 bits (345), Expect = 1e-33
Identities = 73/166 (43%), Positives = 105/166 (63%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+PK + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 73/166 (43%), Positives = 105/166 (63%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
++L DG FMPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G +
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+PK + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQL 173
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 142 bits (344), Expect = 2e-33
Identities = 74/166 (44%), Positives = 103/166 (62%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 140 bits (338), Expect = 8e-33
Identities = 74/162 (45%), Positives = 99/162 (61%), Gaps = 2/162 (1%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 551 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 727
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 728 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 140 bits (338), Expect = 8e-33
Identities = 74/162 (45%), Positives = 99/162 (61%), Gaps = 2/162 (1%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 551 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 727
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 728 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 140 bits (338), Expect = 8e-33
Identities = 74/162 (45%), Positives = 99/162 (61%), Gaps = 2/162 (1%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 551 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 727
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 728 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 140 bits (338), Expect = 8e-33
Identities = 74/162 (45%), Positives = 99/162 (61%), Gaps = 2/162 (1%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 551 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 727
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 728 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 140 bits (338), Expect = 8e-33
Identities = 74/162 (45%), Positives = 99/162 (61%), Gaps = 2/162 (1%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 551 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 727
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 728 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 140 bits (338), Expect = 8e-33
Identities = 74/162 (45%), Positives = 99/162 (61%), Gaps = 2/162 (1%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 551 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 727
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 728 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 140 bits (338), Expect = 8e-33
Identities = 74/162 (45%), Positives = 99/162 (61%), Gaps = 2/162 (1%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 551 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 727
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 728 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 140 bits (338), Expect = 8e-33
Identities = 74/162 (45%), Positives = 99/162 (61%), Gaps = 2/162 (1%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 551 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 727
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 728 -ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
I Y Y + W +E LVAKGL +++G+SNFNS QI
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 139 bits (336), Expect = 1e-32
Identities = 72/166 (43%), Positives = 100/166 (60%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G A+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAVRS 67
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +LV A SL L++ DL+LIH+PMSLK G
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEE 127
Query: 716 SIP-KISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P + + + D W ME GLAKSIGVSNFN Q+
Sbjct: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 136 bits (328), Expect = 1e-31
Identities = 69/155 (44%), Positives = 94/155 (60%), Gaps = 1/155 (0%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 748
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 749 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+ ++DAW ME+LV +GL K++GVSNF+ QI
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 136 bits (328), Expect = 1e-31
Identities = 69/155 (44%), Positives = 94/155 (60%), Gaps = 1/155 (0%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 748
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 749 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+ ++DAW ME+LV +GL K++GVSNF+ QI
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 136 bits (328), Expect = 1e-31
Identities = 69/155 (44%), Positives = 94/155 (60%), Gaps = 1/155 (0%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 748
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 749 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+ ++DAW ME+LV +GL K++GVSNF+ QI
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 136 bits (328), Expect = 1e-31
Identities = 69/155 (44%), Positives = 94/155 (60%), Gaps = 1/155 (0%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 748
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 749 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+ ++DAW ME+LV +GL K++GVSNF+ QI
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 136 bits (328), Expect = 1e-31
Identities = 69/155 (44%), Positives = 94/155 (60%), Gaps = 1/155 (0%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 748
LFI+ KLW TF LV A +L DL L + D++LIH P K G+ PK
Sbjct: 73 LFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 749 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+ ++DAW ME+LV +GL K++GVSNF+ QI
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 134 bits (325), Expect = 3e-31
Identities = 71/166 (42%), Positives = 101/166 (60%), Gaps = 4/166 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKN 535
+KL DG FMPV+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 64
Query: 536 KIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
KI DG+V+R+++F KLW HR +L A SL +L L++ DL+LIH P+S+K G
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 124
Query: 716 SIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
IPK + I + D W +E LAKSIGVSNFN + +
Sbjct: 125 VIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTL 170
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 134 bits (324), Expect = 4e-31
Identities = 76/174 (43%), Positives = 100/174 (57%), Gaps = 20/174 (11%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 715
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 716 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQL 177
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 134 bits (324), Expect = 4e-31
Identities = 76/174 (43%), Positives = 100/174 (57%), Gaps = 20/174 (11%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 715
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 716 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQL 177
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 134 bits (324), Expect = 4e-31
Identities = 76/174 (43%), Positives = 100/174 (57%), Gaps = 20/174 (11%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 715
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 716 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQL 177
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 134 bits (324), Expect = 4e-31
Identities = 76/174 (43%), Positives = 100/174 (57%), Gaps = 20/174 (11%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 715
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 716 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQL 177
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 134 bits (324), Expect = 4e-31
Identities = 76/174 (43%), Positives = 100/174 (57%), Gaps = 20/174 (11%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS----------- 715
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K +
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 716 --SIPKI-------SSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S P++ S+++ S+ D++D W MEDLV GL K+IGVSNFN Q+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQL 177
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 134 bits (323), Expect = 5e-31
Identities = 69/158 (43%), Positives = 99/158 (62%), Gaps = 4/158 (2%)
Frame = +2
Query: 389 MPVIALGTALLP--PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVR 559
MPV+ GT P PR E+ + AI+ G+R ID+AY+Y NE+ +G AI++KI DG+V+
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 60
Query: 560 RDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK-ISS 736
R+++F KLW TF + +V+ A SL L L++ DL+L+H PM+LK G + +PK +
Sbjct: 61 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENG 120
Query: 737 VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+ + D W ME GLAKSIGVSNFN Q+
Sbjct: 121 KVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 158
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 132 bits (319), Expect = 2e-30
Identities = 68/155 (43%), Positives = 92/155 (59%), Gaps = 1/155 (0%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
MP++ LGT P E V+ AID GYR ID AY+Y NE +G+AI+ KI + V+R++
Sbjct: 13 MPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKRED 72
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPKISSVIQY 748
LFI KLW TF LV A +L D L + D++LIH P K G+ PK
Sbjct: 73 LFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132
Query: 749 -SEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+ ++DAW ME+LV +GL K++GVSNF+ QI
Sbjct: 133 GGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 127 bits (306), Expect = 6e-29
Identities = 67/156 (42%), Positives = 95/156 (60%), Gaps = 4/156 (2%)
Frame = +2
Query: 395 VIALGT---ALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRD 565
V+ GT A +P E + AI+ G+R ID+A++Y NE+ +G AI++KI DG+V+R+
Sbjct: 1 VLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRE 60
Query: 566 ELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK-ISSVI 742
++F KLW HR +LV A SL +L L++ DL+LIH P+S+K G IPK + I
Sbjct: 61 DIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKI 120
Query: 743 QYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
+ D W +E GLAKSIGVSNFN Q+
Sbjct: 121 LFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 156
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 121 bits (292), Expect = 3e-27
Identities = 68/167 (40%), Positives = 96/167 (57%), Gaps = 5/167 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 532
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 533 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 712
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 713 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P+ + Y + + W ME GL KS+GVSNFN Q+
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQL 176
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 121 bits (292), Expect = 3e-27
Identities = 68/167 (40%), Positives = 96/167 (57%), Gaps = 5/167 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 532
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 533 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 712
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 713 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P+ + Y + + W ME GL KS+GVSNFN Q+
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQL 176
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 121 bits (292), Expect = 3e-27
Identities = 68/167 (40%), Positives = 96/167 (57%), Gaps = 5/167 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 532
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 533 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 712
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 713 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P+ + Y + + W ME GL KS+GVSNFN Q+
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQL 176
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 121 bits (292), Expect = 3e-27
Identities = 68/167 (40%), Positives = 96/167 (57%), Gaps = 5/167 (2%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGTALLP---PR-LTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIK 532
+ L DG +P+I LGT P P+ V+ AID GYR ID AYIY NE +G+AI+
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 533 NKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGN 712
KI +G VRR+++F GKLW+T H ++V +L L L++ DL++I PM+ K G+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 713 SSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
P+ + Y + + W ME GL KS+GVSNFN Q+
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQL 176
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 120 bits (289), Expect = 7e-27
Identities = 63/148 (42%), Positives = 90/148 (60%), Gaps = 5/148 (3%)
Frame = +2
Query: 347 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 517
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 518 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 697
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 698 LKE-GNSSIPK-ISSVIQYSEFDYMDAW 775
+K+ G +PK S I + D W
Sbjct: 125 MKQPGKELLPKDASGEIILETVELCDTW 152
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 120 bits (289), Expect = 7e-27
Identities = 63/148 (42%), Positives = 90/148 (60%), Gaps = 5/148 (3%)
Frame = +2
Query: 347 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 517
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 518 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 697
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 698 LKE-GNSSIPK-ISSVIQYSEFDYMDAW 775
+K+ G +PK S I + D W
Sbjct: 125 MKQPGKELLPKDASGEIILETVELCDTW 152
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 114 bits (275), Expect = 4e-25
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +2
Query: 347 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 517
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 518 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 697
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 698 LK 703
+K
Sbjct: 125 MK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 114 bits (275), Expect = 4e-25
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +2
Query: 347 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 517
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 518 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 697
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 698 LK 703
+K
Sbjct: 125 MK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 114 bits (275), Expect = 4e-25
Identities = 56/122 (45%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Frame = +2
Query: 347 VKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLI 517
+K+ +++L DG FMPV+ GT P E + AID+G+R ID+AY+Y NE+ +
Sbjct: 5 LKQSHSVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEV 64
Query: 518 GKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMS 697
G+AI KI DGTV+R+E+F KLW+TF R +LV A SL LG ++ DLF+IH P +
Sbjct: 65 GQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFA 124
Query: 698 LK 703
+K
Sbjct: 125 MK 126
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 110 bits (264), Expect = 8e-24
Identities = 59/137 (43%), Positives = 79/137 (57%), Gaps = 2/137 (1%)
Frame = +2
Query: 371 LRDGTFMPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDG 550
L G MP+I LGT P V+ A+ +GYR ID A IYGNE IG+A+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 551 -TVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNSSIPK 727
V R+ELF+ KLW+T H + VE A R +LADL LE+ DL+L+H P + + G++ PK
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 728 -ISSVIQYSEFDYMDAW 775
I Y Y + W
Sbjct: 128 NADGTICYDSTHYKETW 144
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 109 bits (263), Expect = 1e-23
Identities = 54/127 (42%), Positives = 81/127 (63%), Gaps = 3/127 (2%)
Frame = +2
Query: 344 SVKEVATLKLRDGTFMPVIALGTAL---LPPRLTTEIVETAIDMGYRAIDTAYIYGNEKL 514
S + ++KL DG FMP++ GT++ + E V+ AID+GYR ID+AY + NE+
Sbjct: 2 SFNRLLSVKLNDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEG 61
Query: 515 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPM 694
IG+AI+ KI +GTV+R ++F K+W TF R +LV+ +SL L L + DL+L H P+
Sbjct: 62 IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121
Query: 695 SLKEGNS 715
L+ G S
Sbjct: 122 PLQPGRS 128
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 109 bits (261), Expect = 2e-23
Identities = 53/105 (50%), Positives = 66/105 (62%)
Frame = +2
Query: 389 MPVIALGTALLPPRLTTEIVETAIDMGYRAIDTAYIYGNEKLIGKAIKNKIDDGTVRRDE 568
+P + L + P TE V+ AID GYR D AY Y NE+ +G I+ KI +G VRR++
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 569 LFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLK 703
LFI KLW T H+ LVETACR SL L L + DL+LIH PM K
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 100 bits (239), Expect(2) = 2e-22
Identities = 51/113 (45%), Positives = 70/113 (61%), Gaps = 1/113 (0%)
Frame = +2
Query: 515 IGKAIKNKIDDGTVRRDELFIMGKLWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPM 694
+G AI++KI DG+V+R+++F KLW HR +LV A SL +L L++ DL+LIH P+
Sbjct: 27 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 86
Query: 695 SLKEGNSSIPK-ISSVIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
S+K G IPK + I + D W +E GLAKSIGVSNFN Q+
Sbjct: 87 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 139
Score = 26.2 bits (55), Expect(2) = 2e-22
Identities = 10/16 (62%), Positives = 12/16 (75%)
Frame = +2
Query: 365 LKLRDGTFMPVIALGT 412
+KL DG FMPV+ GT
Sbjct: 6 VKLNDGHFMPVLGFGT 21
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 42.3 bits (95), Expect = 0.002
Identities = 18/43 (41%), Positives = 26/43 (60%)
Frame = +2
Query: 587 LWSTFHRTDLVETACRISLADLGLEFFDLFLIHNPMSLKEGNS 715
+W TF R +LV+ +SL L L + DL+L H P+ L+ G S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 35.5 bits (78), Expect = 0.26
Identities = 17/31 (54%), Positives = 18/31 (58%)
Frame = +2
Query: 758 DYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
D W ME GLAKSIGVSNFN Q+
Sbjct: 20 DLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 50
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 33.5 bits (73), Expect = 1.0
Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Frame = +2
Query: 692 MSLKEGNSSIPKISS-VIQYSEFDYMDAWFGMEDLVAKGLAKSIGVSNFNSTQI 850
M+ K G+ P+ + Y + + W ME GL KS+GVSNFN Q+
Sbjct: 1 MAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQL 54
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,169,731
Number of Sequences: 237096
Number of extensions: 2742058
Number of successful extensions: 11521
Number of sequences better than 10.0: 93
Number of HSP's better than 10.0 without gapping: 10841
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11383
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11381686510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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