Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= e96h0727
(788 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 79 9e-14
UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 79 2e-13
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 76 9e-13
UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 75 2e-12
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 73 8e-12
UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 73 8e-12
UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 71 4e-11
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 70 8e-11
UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 68 2e-10
UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145, w... 67 4e-10
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 66 7e-10
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 66 9e-10
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 65 2e-09
UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 65 2e-09
UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 64 3e-09
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 64 3e-09
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 64 4e-09
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 64 4e-09
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 64 5e-09
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 64 5e-09
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 64 5e-09
UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 63 7e-09
UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 63 9e-09
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 62 1e-08
UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16; Pezizomy... 62 2e-08
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 61 3e-08
UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 61 3e-08
UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 61 3e-08
UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB... 61 4e-08
UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 61 4e-08
UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 60 5e-08
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 60 8e-08
UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 60 8e-08
UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 59 1e-07
UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315 ... 59 1e-07
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 59 1e-07
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 58 3e-07
UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 58 3e-07
UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:... 58 3e-07
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 58 3e-07
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 57 4e-07
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 57 4e-07
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 57 4e-07
UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 57 4e-07
UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1; ... 57 4e-07
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 57 6e-07
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 57 6e-07
UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 57 6e-07
UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 56 8e-07
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 56 1e-06
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 56 1e-06
UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2; ... 56 1e-06
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 55 2e-06
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 55 2e-06
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 54 3e-06
UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.3... 54 3e-06
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 54 3e-06
UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 54 4e-06
UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 54 4e-06
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 54 4e-06
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 54 4e-06
UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 54 4e-06
UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 54 5e-06
UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 54 5e-06
UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 54 5e-06
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 53 7e-06
UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of str... 53 7e-06
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 53 7e-06
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 53 9e-06
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 9e-06
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 53 9e-06
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 52 1e-05
UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 52 1e-05
UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 52 1e-05
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 52 1e-05
UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 52 1e-05
UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose dehydrogenase:P... 52 2e-05
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 52 2e-05
UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 52 2e-05
UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 52 2e-05
UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 51 3e-05
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 51 3e-05
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 51 3e-05
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 51 3e-05
UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus Pela... 51 4e-05
UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 51 4e-05
UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with NAD(P)-bi... 50 5e-05
UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep: Bll... 50 7e-05
UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulo... 50 7e-05
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 50 7e-05
UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 50 7e-05
UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 7e-05
UniRef50_Q9V8M5-2 Cluster: Isoform C of Q9V8M5 ; n=1; Drosophila... 50 9e-05
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 50 9e-05
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 50 9e-05
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 9e-05
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 50 9e-05
UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: Bt... 50 9e-05
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 50 9e-05
UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 49 1e-04
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 49 2e-04
UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 49 2e-04
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 49 2e-04
UniRef50_Q0C8I2 Cluster: Predicted protein; n=3; Pezizomycotina|... 49 2e-04
UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 2e-04
UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 48 3e-04
UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 3e-04
UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 3e-04
UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovari... 48 3e-04
UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and ... 48 3e-04
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 48 4e-04
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 48 4e-04
UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 4e-04
UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_150... 48 4e-04
UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 47 5e-04
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 47 5e-04
UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase p... 47 5e-04
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 47 5e-04
UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 47 6e-04
UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 47 6e-04
UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 47 6e-04
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 46 8e-04
UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetell... 46 8e-04
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 46 8e-04
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 46 8e-04
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 46 8e-04
UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza sativa|... 46 0.001
UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase, put... 46 0.001
UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 46 0.001
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 46 0.001
UniRef50_Q8TUC1 Cluster: Predicted protein; n=4; Methanosarcinac... 46 0.001
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 46 0.001
UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL ... 45 0.002
UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogena... 45 0.002
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 45 0.002
UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 45 0.002
UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 45 0.002
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 45 0.002
UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 45 0.002
UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5; Prote... 44 0.003
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 44 0.003
UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 44 0.003
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 44 0.003
UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 44 0.003
UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.003
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 44 0.003
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.003
UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 44 0.003
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 44 0.003
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 44 0.004
UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 44 0.004
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 44 0.004
UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 44 0.004
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 44 0.006
UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=... 44 0.006
UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 43 0.008
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 43 0.008
UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 43 0.008
UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3... 43 0.010
UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.010
UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 43 0.010
UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 43 0.010
UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 43 0.010
UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 43 0.010
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 43 0.010
UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1; Gluconoba... 42 0.013
UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobac... 42 0.013
UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 42 0.013
UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.013
UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.013
UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 42 0.013
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 42 0.018
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.018
UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.018
UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 42 0.018
UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6; Trypan... 42 0.018
UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 42 0.018
UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.023
UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2; Ar... 42 0.023
UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12; c... 42 0.023
UniRef50_Q6KZX0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 41 0.031
UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 41 0.041
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 41 0.041
UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 41 0.041
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 41 0.041
UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2; ... 41 0.041
UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 40 0.054
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 40 0.054
UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 40 0.054
UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces cap... 40 0.071
UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 40 0.094
UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 40 0.094
UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH gro... 40 0.094
UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium ja... 39 0.12
UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep: Glr... 39 0.12
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 39 0.12
UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH gro... 39 0.12
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 39 0.12
UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 39 0.16
UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 39 0.16
UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 39 0.16
UniRef50_A4ENK2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 39 0.16
UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.22
UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 38 0.22
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 38 0.29
UniRef50_Q9YFQ6 Cluster: L-lysine 6-dehydrogenase; n=1; Aeropyru... 38 0.29
UniRef50_Q220G7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.38
UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.38
UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.38
UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.38
UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2; ... 38 0.38
UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 38 0.38
UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 ... 37 0.50
UniRef50_UPI00003C03F8 Cluster: PREDICTED: similar to CG4747-PA;... 37 0.50
UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus ... 37 0.50
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 37 0.66
UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar... 37 0.66
UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 37 0.66
UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 37 0.66
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 37 0.66
UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomona... 37 0.66
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 36 0.88
UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 36 0.88
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 0.88
UniRef50_Q2RVS2 Cluster: Prephenate dehydrogenase; n=1; Rhodospi... 36 0.88
UniRef50_Q1YFU0 Cluster: Posibble methylase involved in ubiquino... 36 0.88
UniRef50_A4SGI3 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 0.88
UniRef50_A4ES45 Cluster: Methyltransferase type 11; n=1; Roseoba... 36 0.88
UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 0.88
UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 0.88
UniRef50_P71825 Cluster: Uncharacterized oxidoreductase Rv0770/M... 36 0.88
UniRef50_A4ARS6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.2
UniRef50_A3ZZH5 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161... 36 1.2
UniRef50_Q944B6 Cluster: Arogenate dehydrogenase 1, chloroplast ... 36 1.2
UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to 3-hydroxyi... 36 1.5
UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;... 36 1.5
UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6... 36 1.5
UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 36 1.5
UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.5
UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1; ... 36 1.5
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 36 1.5
UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.5
UniRef50_Q0U6Q6 Cluster: Putative uncharacterized protein; n=5; ... 36 1.5
UniRef50_A1U1I8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 1.5
UniRef50_Q5PAV2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 35 2.0
UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 35 2.0
UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 2.0
UniRef50_A6VZU5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.0
UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella ve... 35 2.0
UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 35 2.7
UniRef50_Q2S7E0 Cluster: Phosphoglycerate dehydrogenase and rela... 35 2.7
UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 35 2.7
UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 35 2.7
UniRef50_A6G079 Cluster: Leucine dehydrogenase; n=1; Plesiocysti... 35 2.7
UniRef50_A3Y0Y8 Cluster: Putative tartronate semialdehyde reduct... 35 2.7
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 2.7
UniRef50_UPI00006CB611 Cluster: hypothetical protein TTHERM_0044... 34 3.5
UniRef50_UPI000050FDFD Cluster: COG0569: K+ transport systems, N... 34 3.5
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 34 3.5
UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 34 3.5
UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 3.5
UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep... 34 3.5
UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 34 3.5
UniRef50_UPI0000E221EA Cluster: PREDICTED: similar to NMDAR1 sub... 34 4.7
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 34 4.7
UniRef50_Q7U3D8 Cluster: Multidrug efflux transporter, MFS famil... 34 4.7
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 34 4.7
UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 34 4.7
UniRef50_A3HES3 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 4.7
UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ... 34 4.7
UniRef50_A7QQA4 Cluster: Chromosome undetermined scaffold_141, w... 33 6.2
UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ... 33 6.2
UniRef50_Q4SYH9 Cluster: Chromosome undetermined SCAF12061, whol... 33 8.2
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 33 8.2
UniRef50_O67636 Cluster: Prephenate dehydrogenase; n=1; Aquifex ... 33 8.2
UniRef50_Q2BJD5 Cluster: Probable UDP-glucose/GDP-mannose dehydr... 33 8.2
UniRef50_Q0SBI0 Cluster: Probable oxidoreductase; n=1; Rhodococc... 33 8.2
UniRef50_Q0S6F7 Cluster: 3-demethylubiquinone-9 3-O-methyltransf... 33 8.2
UniRef50_A6TCR4 Cluster: 2-ketoacid reductase; n=1; Klebsiella p... 33 8.2
UniRef50_A6NX21 Cluster: Putative uncharacterized protein; n=1; ... 33 8.2
UniRef50_A3U721 Cluster: Putative uncharacterized protein; n=1; ... 33 8.2
UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 8.2
UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=... 33 8.2
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 79.4 bits (187), Expect = 9e-14
Identities = 35/66 (53%), Positives = 46/66 (69%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG K+ + P+L MGA HCG G+GQ+AKL NN+++ IT + T E MN+GIK
Sbjct: 155 FMVGGDKQVLNSADPILMKMGANVLHCGDSGAGQIAKLCNNLILAITMIGTCEGMNLGIK 214
Query: 692 MGLEPK 709
MGL+PK
Sbjct: 215 MGLDPK 220
Score = 72.1 bits (169), Expect = 1e-11
Identities = 34/71 (47%), Positives = 45/71 (63%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L + +V D LG +G++ HA KGSLLID STI P V +++ G F DAPVS
Sbjct: 83 TMLPNGDIVKDTVLGTNGILKHASKGSLLIDCSTIQPQVAQEVSKATYSAGFKFLDAPVS 142
Query: 477 GGVMGAQNATL 509
GGV GA+ TL
Sbjct: 143 GGVTGAEAGTL 153
Score = 42.3 bits (95), Expect = 0.013
Identities = 19/28 (67%), Positives = 23/28 (82%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYD 204
+AF+G+GNMG MA NLVKKG TVR +D
Sbjct: 26 LAFIGIGNMGSRMANNLVKKGETVRVFD 53
>UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Dictyostelium discoideum AX4
Length = 321
Score = 78.6 bits (185), Expect = 2e-13
Identities = 31/66 (46%), Positives = 48/66 (72%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG ++DF + L+ MG HCG +G+GQVAK+ NN+++GI+ +A +E MN+G+K
Sbjct: 156 FMVGGSEQDFNTAKTYLECMGKNIVHCGDVGTGQVAKVCNNLVLGISMIAVSEAMNLGVK 215
Query: 692 MGLEPK 709
G++PK
Sbjct: 216 QGMDPK 221
Score = 57.2 bits (132), Expect = 4e-07
Identities = 28/71 (39%), Positives = 44/71 (61%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L ++ V +VY G++G+ + G+LL+DSSTIDP +++ IA + D PVS
Sbjct: 84 TMLPASAHVKNVYCGENGIFQTVRPGTLLLDSSTIDPATAREVASIAKKHQSTMLDCPVS 143
Query: 477 GGVMGAQNATL 509
GG GA+ TL
Sbjct: 144 GGTGGAEAGTL 154
Score = 53.2 bits (122), Expect = 7e-06
Identities = 24/51 (47%), Positives = 33/51 (64%)
Frame = +1
Query: 91 RAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
R S+++ K V F+GLGNMGG A NL+KKG + +D SKD +N + G
Sbjct: 15 RYMSTSSSKTVGFIGLGNMGGHQAINLIKKGHNLIVFDMSKDNMNRLKEKG 65
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 76.2 bits (179), Expect = 9e-13
Identities = 32/66 (48%), Positives = 48/66 (72%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG +++F + LL MG+ +CG +G+GQ AK+ NNML+ I+ + TAE MN+GI+
Sbjct: 173 FMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIR 232
Query: 692 MGLEPK 709
+GL+PK
Sbjct: 233 LGLDPK 238
Score = 63.7 bits (148), Expect = 5e-09
Identities = 32/71 (45%), Positives = 46/71 (64%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L ++ ++ Y G +G++ KKGSLLIDSSTIDP V K++ + G F DAPVS
Sbjct: 101 TMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVS 160
Query: 477 GGVMGAQNATL 509
GGV A++ L
Sbjct: 161 GGVGAARSGNL 171
Score = 38.3 bits (85), Expect = 0.22
Identities = 21/43 (48%), Positives = 27/43 (62%)
Frame = +1
Query: 91 RAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDA 219
R+ +S T V F+GLGNMG MA NL+K G+ + YD DA
Sbjct: 34 RSVASKTP--VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDA 74
>UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 299
Score = 74.9 bits (176), Expect = 2e-12
Identities = 32/66 (48%), Positives = 45/66 (68%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG DFER P+L MG HCG G GQVAK+ NN+++GI+ A +E M++G+
Sbjct: 134 FMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQVAKVCNNLVLGISMAAVSEAMSLGVA 193
Query: 692 MGLEPK 709
+G++PK
Sbjct: 194 LGIDPK 199
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/63 (46%), Positives = 36/63 (57%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V V G++GV+A G+ +IDSSTIDP + + E G F DAPVSGG GA
Sbjct: 70 VRSVLSGENGVLAGLGAGATVIDSSTIDPASAQAFGALVREHGGAFVDAPVSGGTGGAAA 129
Query: 501 ATL 509
TL
Sbjct: 130 GTL 132
Score = 42.3 bits (95), Expect = 0.013
Identities = 21/45 (46%), Positives = 26/45 (57%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
+ F+GLG+MG MA NL+K G V +D S DAL A G A
Sbjct: 3 IGFIGLGHMGAPMALNLLKAGHEVHAFDLSADALRALQDAGAQVA 47
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 72.9 bits (171), Expect = 8e-12
Identities = 32/66 (48%), Positives = 43/66 (65%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
F+ GG ED + P+L+ MG FH G G+GQ AK+ NNML+GI TAE + +G+K
Sbjct: 135 FIVGGAAEDLAHARPVLEAMGKNIFHAGGAGAGQTAKICNNMLLGILMAGTAEALALGVK 194
Query: 692 MGLEPK 709
GL+PK
Sbjct: 195 NGLDPK 200
Score = 66.1 bits (154), Expect = 9e-10
Identities = 34/71 (47%), Positives = 44/71 (61%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S+L + K V +YLG +G+ A KG+L+ID STID +++ A EKGL DAPVS
Sbjct: 63 SMLPAGKHVAGLYLGDNGLFARLPKGALVIDCSTIDAGTARKVAEGAREKGLSMLDAPVS 122
Query: 477 GGVMGAQNATL 509
GG GA TL
Sbjct: 123 GGTAGAAAGTL 133
Score = 53.6 bits (123), Expect = 5e-06
Identities = 25/43 (58%), Positives = 30/43 (69%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
+N+AF+GLGNMGG MA NL+ KGF V +D S DAL A G
Sbjct: 2 ENIAFIGLGNMGGPMAVNLLNKGFKVSAFDLSADALAKVAAAG 44
>UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pseudomonas aeruginosa
Length = 298
Score = 72.9 bits (171), Expect = 8e-12
Identities = 33/66 (50%), Positives = 45/66 (68%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+F+ GG E F R+ P+L+ MG FH G G+GQVAK+ NNML+GI TAE + +G+
Sbjct: 134 SFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQVAKICNNMLLGILMAGTAEALALGV 193
Query: 689 KMGLEP 706
K GL+P
Sbjct: 194 KNGLDP 199
Score = 61.7 bits (143), Expect = 2e-08
Identities = 33/71 (46%), Positives = 43/71 (60%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S+L + + V +YLG DG++A LLID STI P +++ A KGL DAPVS
Sbjct: 63 SMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAKGLTLLDAPVS 122
Query: 477 GGVMGAQNATL 509
GGV GA+ TL
Sbjct: 123 GGVGGARAGTL 133
Score = 46.4 bits (105), Expect = 8e-04
Identities = 24/51 (47%), Positives = 30/51 (58%)
Frame = +1
Query: 118 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQ 270
++AFLGLGNMGG MAANL+K G V +D A+ + G A LQ
Sbjct: 3 DIAFLGLGNMGGPMAANLLKAGHRVNVFDLQPKAVLGLVEQGAQGADSALQ 53
>UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Paracoccus methylutens|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Paracoccus
methylutens
Length = 302
Score = 70.5 bits (165), Expect = 4e-11
Identities = 33/71 (46%), Positives = 49/71 (69%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
+++ + + VL+++LG DGV+A KGS+ IDSSTID +++ E+G+ DAPVS
Sbjct: 63 TMVPTGRHVLEIFLGDDGVLAKMAKGSMAIDSSTIDTADARRLHAAGRERGIAVLDAPVS 122
Query: 477 GGVMGAQNATL 509
GGVMGA+ TL
Sbjct: 123 GGVMGAEAGTL 133
Score = 66.9 bits (156), Expect = 5e-10
Identities = 30/66 (45%), Positives = 43/66 (65%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG ED ER+ P+L+ MG + FH G+ G GQ AKL NN+L GI+ +A +E +
Sbjct: 135 FMVGGSAEDLERARPVLEAMGRRIFHAGEPGVGQAAKLCNNLLAGISMIAVSEAFALARH 194
Query: 692 MGLEPK 709
+GL+ +
Sbjct: 195 LGLDAR 200
Score = 43.6 bits (98), Expect = 0.006
Identities = 23/46 (50%), Positives = 27/46 (58%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAT 258
V FLGLG MG MA NL G V YDPS++ AAK G+ A+
Sbjct: 4 VGFLGLGRMGFPMARNLATAGHDVHVYDPSEEVGRKAAKAGLKTAS 49
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 69.7 bits (163), Expect = 8e-11
Identities = 33/69 (47%), Positives = 49/69 (71%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L + ++V VYL ++G++ HAKKG+LL+D ST++P++ + A GL + APVSGG
Sbjct: 85 LPTPQIVEMVYLSEEGIIHHAKKGALLVDFSTVNPDLNDSLHKEASTLGLRYLGAPVSGG 144
Query: 483 VMGAQNATL 509
V+GA NATL
Sbjct: 145 VIGAVNATL 153
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLMGITGMATAECMNMGIK 691
M GG K+D++ + + ++G +H G S G KL NN+++G A AE + +G K
Sbjct: 156 MVGGGKDDYDSASEIFGIVGKNIYHLGLSSSVGTRLKLLNNLMIGFYTEAVAETIVLGEK 215
Query: 692 MGLE 703
MG++
Sbjct: 216 MGID 219
Score = 36.7 bits (81), Expect = 0.66
Identities = 16/44 (36%), Positives = 27/44 (61%)
Frame = +1
Query: 112 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
++ + F+GLGNMG M+ NL+K + V G+D + A+ + G
Sbjct: 21 NRKLGFIGLGNMGLPMSINLLKANYEVYGFDTNAKAVELFTEAG 64
>UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Coxiella burnetii
Length = 297
Score = 68.1 bits (159), Expect = 2e-10
Identities = 30/66 (45%), Positives = 45/66 (68%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG KEDFER+ +L ++G K + G G+G AK+ NNML+GI+ +A +E + K
Sbjct: 135 FMVGGEKEDFERAKRVLGILGKKIIYAGSDGAGAAAKICNNMLLGISMIAVSEAFVLADK 194
Query: 692 MGLEPK 709
+GL+P+
Sbjct: 195 LGLDPQ 200
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/71 (33%), Positives = 41/71 (57%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L ++ V + L G+ A + ++ IDSS+ID +++ A ++G+ DAPVS
Sbjct: 63 TMLQTSDQVRNCCLSAKGIFATINRQAIYIDSSSIDIEGSRELHKEAKKRGISMLDAPVS 122
Query: 477 GGVMGAQNATL 509
GGV A+ A L
Sbjct: 123 GGVAAAEAAGL 133
Score = 40.7 bits (91), Expect = 0.041
Identities = 19/45 (42%), Positives = 26/45 (57%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
+ F+GLG+MG M NL+K V+ YD +A+ A K G T A
Sbjct: 4 IGFIGLGHMGQPMVNNLIKNNCLVKVYDVIDEAVEKAVKTGATAA 48
>UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 299
Score = 67.3 bits (157), Expect = 4e-10
Identities = 37/102 (36%), Positives = 55/102 (53%), Gaps = 11/102 (10%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM G KE +E+ P+LK MG F+CG+IG GQ+AK+ NM + I ++ E + +G
Sbjct: 139 FMVGAEKELYEKISPILKEMGKNIFNCGKIGEGQIAKMCGNMALAIQMISVCEALALGKN 198
Query: 692 MGLEPKF-----------CWTC*TTHRLAPGRPR*LSSSPDW 784
MG++P CWT T+ APG + S+ D+
Sbjct: 199 MGMDPAMLSSIMSVSSSRCWTV-DTYNPAPGVMPNVPSNKDY 239
Score = 35.5 bits (78), Expect = 1.5
Identities = 19/48 (39%), Positives = 27/48 (56%)
Frame = +3
Query: 366 KKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
K +LIDSSTI P ++ +A + + DAPVSG V A+ T+
Sbjct: 90 KSKKILIDSSTISPYTSYELAKMAQDTQNIYADAPVSGSVSEAKLGTI 137
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 66.5 bits (155), Expect = 7e-10
Identities = 30/65 (46%), Positives = 41/65 (63%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG DFE +LP+LK +G K HCG GSGQ KL N +L GI +A AE + + ++
Sbjct: 140 MVGGDISDFEEALPVLKSIGEKIVHCGPSGSGQAVKLCNQVLCGIHAIAAAEAIQLSEQL 199
Query: 695 GLEPK 709
G+ P+
Sbjct: 200 GIAPE 204
Score = 49.6 bits (113), Expect = 9e-05
Identities = 27/65 (41%), Positives = 37/65 (56%)
Frame = +3
Query: 315 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 494
K V + LG G+ +AK +L+ID STI ++ +GL F DAPV+GG +GA
Sbjct: 73 KDVQQLILGSGGIAEYAKPQALIIDCSTIGKTAAYELATNLKLQGLRFLDAPVTGGDVGA 132
Query: 495 QNATL 509
N TL
Sbjct: 133 INGTL 137
Score = 37.9 bits (84), Expect = 0.29
Identities = 21/50 (42%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS--KDALNAAAKNGVTPATPL 264
+A GLG MG MA NLVK G+ GY+ + + ++ AAK GV T +
Sbjct: 6 IAVFGLGVMGSPMAQNLVKNGYQTVGYNRTLERPSVQEAAKAGVKVVTSI 55
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 66.1 bits (154), Expect = 9e-10
Identities = 32/63 (50%), Positives = 44/63 (69%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V +VY G +G++ +AK+G+ LID +T P++ K+I A EK L DAPVSGG +GAQN
Sbjct: 72 VEEVYFGSNGIIENAKEGAYLIDMTTSKPSLAKKIAEAAKEKALFALDAPVSGGDIGAQN 131
Query: 501 ATL 509
TL
Sbjct: 132 GTL 134
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/67 (38%), Positives = 35/67 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG KE FE +P+ +MG + G GSGQ K+ N + + + AE M
Sbjct: 135 AIMVGGEKEAFEACMPIFSLMGENIQYQGPAGSGQHTKMCNQIAIAAGMIGVAEAMAYAQ 194
Query: 689 KMGLEPK 709
K GLEP+
Sbjct: 195 KSGLEPE 201
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 65.3 bits (152), Expect = 2e-09
Identities = 35/72 (48%), Positives = 43/72 (59%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G + MAGG+ DFERSLPLLKV G + H G GSGQ+ KL N M++GIT A A
Sbjct: 134 GAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVGITIGAVA 192
Query: 668 ECMNMGIKMGLE 703
E + K G +
Sbjct: 193 EALLFATKGGAD 204
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/71 (38%), Positives = 37/71 (52%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S+L + VV DV + GV A K GSL +D ++I P + G+ D PVS
Sbjct: 71 SMLENGAVVQDVLFAQ-GVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVS 129
Query: 477 GGVMGAQNATL 509
GG +GA+ TL
Sbjct: 130 GGTVGAEQGTL 140
>UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Micrococcineae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 300
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/60 (53%), Positives = 41/60 (68%)
Frame = +3
Query: 330 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
VYLG+DGV+AHA + +LL+DSSTID + + A G F DAPVSGG+ GA+ TL
Sbjct: 74 VYLGEDGVLAHADRRTLLVDSSTIDIASAQALHDAAAAAGFRFVDAPVSGGMSGAKAGTL 133
Score = 54.4 bits (125), Expect = 3e-06
Identities = 25/48 (52%), Positives = 33/48 (68%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
VA++GLGNMGG M+ANL K G VRG+D + +A+ AA GV P +
Sbjct: 4 VAWIGLGNMGGSMSANLAKAGHDVRGFDLNPEAVAAAEAGGVKPVASI 51
Score = 35.9 bits (79), Expect = 1.2
Identities = 19/69 (27%), Positives = 34/69 (49%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG + ++ M + G +GQ AK+ NN+++ I +TAE + +
Sbjct: 135 FMIGGDAGAVAEATEYIRPMASNIIPTGGPTTGQAAKICNNLMLFINLASTAEGAVLAER 194
Query: 692 MGLEPKFCW 718
+GL+ + W
Sbjct: 195 LGLDKQVFW 203
>UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=13;
Bacillaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Oceanobacillus iheyensis
Length = 299
Score = 64.5 bits (150), Expect = 3e-09
Identities = 31/69 (44%), Positives = 44/69 (63%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L SNK V VYL K G++ H ++ID+ST+ P + +Q+ E+ + F APVSGG
Sbjct: 65 LPSNKAVEAVYLNKGGLLDHCNSSQVVIDTSTVAPELNQQLEASLSERSIPFLAAPVSGG 124
Query: 483 VMGAQNATL 509
V+GA+N TL
Sbjct: 125 VVGAENQTL 133
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMAT 664
G + M GG++E F++ +L V+G FH G QI G KL NN+L+G
Sbjct: 127 GAENQTLTVMVGGKEETFQKVKDILNVIGGNVFHVGEQIDKGTTVKLINNLLIGFYTAGV 186
Query: 665 AECMNM 682
+E + +
Sbjct: 187 SEALQI 192
Score = 33.9 bits (74), Expect = 4.7
Identities = 15/41 (36%), Positives = 25/41 (60%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
+ F+GLGNMG M+ L+ G+ V G+D +++ K+G
Sbjct: 4 IGFIGLGNMGLPMSIGLMNSGYEVIGFDVNEERSLLFKKSG 44
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 64.5 bits (150), Expect = 3e-09
Identities = 30/69 (43%), Positives = 44/69 (63%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L ++ +V V LG GV +HAK+G ++ID++T DPN +++ G+GF D PVSGG
Sbjct: 65 LPTSAIVEAVVLGDGGVASHAKRGLIVIDTTTADPNSTRKVAAALDAHGIGFIDGPVSGG 124
Query: 483 VMGAQNATL 509
GA AT+
Sbjct: 125 PKGAATATM 133
Score = 47.6 bits (108), Expect = 4e-04
Identities = 23/72 (31%), Positives = 35/72 (48%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G + + GG E P+L + AKQ H G G+G V KL NN+L G+ + T+
Sbjct: 127 GAATATMTMVLGGADEHIAAVQPVLSAISAKQVHVGPAGAGHVTKLLNNLLTGVHLLVTS 186
Query: 668 ECMNMGIKMGLE 703
E + G++
Sbjct: 187 EAVRAAEAAGVD 198
Score = 43.2 bits (97), Expect = 0.008
Identities = 19/52 (36%), Positives = 31/52 (59%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQ 270
K V +GLGNMG +A++L + GF V G+D + +++ A GV P + +
Sbjct: 2 KTVGVIGLGNMGRGIASSLKRAGFDVLGFDANAESVRQLADEGVRPCASVAE 53
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 64.1 bits (149), Expect = 4e-09
Identities = 31/65 (47%), Positives = 42/65 (64%)
Frame = +3
Query: 315 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 494
+ V+DVY G+DG++A +G +LID ST+D ++ EKG F DAPVSGG MGA
Sbjct: 70 ETVIDVYEGEDGLIAGLSQGKILIDHSTVDRETNVRVAEQIKEKGGAFLDAPVSGGPMGA 129
Query: 495 QNATL 509
+ TL
Sbjct: 130 KAGTL 134
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/68 (39%), Positives = 35/68 (51%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG + FERS +L G H G IGSG V KL NNM++G+ EC K
Sbjct: 137 MCGGEADSFERSKEVLGAYGDYIVHVGPIGSGTVVKLANNMVIGVHQAVLGECYLFVEKA 196
Query: 695 GLEPKFCW 718
G++P +
Sbjct: 197 GVDPAIAY 204
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 64.1 bits (149), Expect = 4e-09
Identities = 29/74 (39%), Positives = 45/74 (60%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G E + M GG +EDF R+ PL +VMG H G G+GQ+ K N +++G+T A
Sbjct: 141 GAREGTLSIMVGGSEEDFGRARPLFEVMGKTVTHVGPSGAGQIVKAANQIVVGLTIEAVC 200
Query: 668 ECMNMGIKMGLEPK 709
E + +G++ G+EP+
Sbjct: 201 EALVLGLRGGVEPQ 214
Score = 62.1 bits (144), Expect = 2e-08
Identities = 37/103 (35%), Positives = 54/103 (52%)
Frame = +3
Query: 201 RSFQRCTERSGQERSDASNSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSL 380
R+ Q+ E + Q + + S ++L + V V G+ GV+ ++GSL
Sbjct: 45 RTHQKAEEFAQQTGARTAKSPKEVAGQSDIIITMLPDSPDVESVVAGEGGVLEGMREGSL 104
Query: 381 LIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
LID STI P V +Q+ A E+G DAPVSGG +GA+ TL
Sbjct: 105 LIDMSTISPAVARQLAAKARERGASMLDAPVSGGDVGAREGTL 147
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 63.7 bits (148), Expect = 5e-09
Identities = 31/65 (47%), Positives = 40/65 (61%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG + FE LP L+V G H G +G+G VAKL NN+L+GI A AE +G K
Sbjct: 134 MCGGDRAAFEAVLPYLQVEGKAIHHLGPVGAGSVAKLCNNLLVGIHTAAMAEAFVLGTKA 193
Query: 695 GLEPK 709
G++PK
Sbjct: 194 GVDPK 198
Score = 46.8 bits (106), Expect = 6e-04
Identities = 23/49 (46%), Positives = 30/49 (61%)
Frame = +3
Query: 363 AKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
A+ G + +D STI K+I + EKG+ F DAPVSGG GA+ TL
Sbjct: 83 AQPGDIFVDHSTIGVRDAKRIAAMCAEKGVQFIDAPVSGGPWGAEAGTL 131
Score = 37.9 bits (84), Expect = 0.29
Identities = 17/42 (40%), Positives = 25/42 (59%)
Frame = +1
Query: 118 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
N+ F+GLG MG MA NL++ G TV Y+ S+ ++ G
Sbjct: 4 NLGFIGLGRMGRHMARNLIRAGHTVTLYNRSQAVVDELVAEG 45
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 63.7 bits (148), Expect = 5e-09
Identities = 34/107 (31%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Frame = +3
Query: 198 LRSFQRCTERSGQER---SDASNSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAK 368
LR++ R +++ + + ++ S SI ++LT + V V +G D +++ K
Sbjct: 27 LRAYNRSQDKADRLKEFGAEISTSIKDVVTNSDVIITMLTDDAAVEKV-MGSDEFISNIK 85
Query: 369 KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
+G+ +ID S+++P + K+ F I EK + + DAPVSGG +GA+ A+L
Sbjct: 86 EGATVIDMSSVNPVITKKYFKILKEKNINYLDAPVSGGTIGAEEASL 132
Score = 52.0 bits (119), Expect = 2e-05
Identities = 27/73 (36%), Positives = 41/73 (56%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G E A M GG +E F++ LLK++G G + SGQ++KL N +++G+T A A
Sbjct: 126 GAEEASLAIMVGGDEETFKQCYDLLKILGNPTL-VGPVTSGQISKLANQIIVGVTIGAVA 184
Query: 668 ECMNMGIKMGLEP 706
E + + K G P
Sbjct: 185 EAVTLCEKSGTNP 197
Score = 42.7 bits (96), Expect = 0.010
Identities = 19/50 (38%), Positives = 32/50 (64%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
+N++F+G+G MG MA NL+K GF +R Y+ S+D + + G +T +
Sbjct: 2 QNISFIGIGLMGFPMAKNLLKSGFNLRAYNRSQDKADRLKEFGAEISTSI 51
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 63.7 bits (148), Expect = 5e-09
Identities = 31/69 (44%), Positives = 44/69 (63%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L + K+V GK+GV + K+G+++ID S++ PN K + A EKG+ + DAPVSGG
Sbjct: 69 LPNAKIVEGTMCGKNGVFENCKEGTVIIDMSSVAPNTTKAMAKKAAEKGIHYIDAPVSGG 128
Query: 483 VMGAQNATL 509
V GA TL
Sbjct: 129 VSGAAAGTL 137
Score = 55.2 bits (127), Expect = 2e-06
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M G E F + P+ V+G +H G+ G G K+ NN+L+G A AE + +G+K
Sbjct: 140 MVGADDETFNKVKPIFDVLGKNIYHVGEAGGGDAIKMVNNLLLGCNMAALAEALTLGVKC 199
Query: 695 GL 700
GL
Sbjct: 200 GL 201
>UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 299
Score = 63.3 bits (147), Expect = 7e-09
Identities = 27/72 (37%), Positives = 45/72 (62%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G E FM GG + F+R+ P+L+ MGA+ F+ G G+GQ+AKL NN++ ++ +
Sbjct: 127 GAREARLTFMVGGARTAFDRAEPVLRQMGARIFYAGASGNGQIAKLCNNLIACVSSAVVS 186
Query: 668 ECMNMGIKMGLE 703
E +G K+G++
Sbjct: 187 EAFILGSKLGMD 198
Score = 50.0 bits (114), Expect = 7e-05
Identities = 28/71 (39%), Positives = 40/71 (56%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
SI+ + V ++Y GV+ A G+LLI+SSTI P + + A + G DAPV+
Sbjct: 63 SIVRNADDVKNLYCTAGGVLDVAAPGALLIESSTIGPAAARAVAAEAAQAGFAMLDAPVA 122
Query: 477 GGVMGAQNATL 509
GG GA+ A L
Sbjct: 123 GGQAGAREARL 133
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/41 (53%), Positives = 28/41 (68%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
+AF+GLGNMG MA NLV+ G V+G+D S+ AL A G
Sbjct: 4 IAFIGLGNMGMPMALNLVRAGHDVQGFDISEAALAGFAGQG 44
>UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=4;
Diptera|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 62.9 bits (146), Expect = 9e-09
Identities = 27/72 (37%), Positives = 42/72 (58%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G + FM GG + ++ +L+ MG K HCG G GQ AKL NNM++ I+ + +
Sbjct: 152 GAEQATLTFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMGQAAKLCNNMMLAISMIGVS 211
Query: 668 ECMNMGIKMGLE 703
E MN+ ++ GL+
Sbjct: 212 EAMNLAVRQGLD 223
Score = 50.8 bits (116), Expect = 4e-05
Identities = 32/73 (43%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
Frame = +3
Query: 297 SILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 470
++L +N +V Y + DGV K ++ IDSSTI P++ K + KG F DAP
Sbjct: 90 TMLPNNAIVDASYDEMTADGV----NKDTIFIDSSTISPDLVKSLQKKISAKGARFIDAP 145
Query: 471 VSGGVMGAQNATL 509
VSGGV GA+ ATL
Sbjct: 146 VSGGVPGAEQATL 158
Score = 49.6 bits (113), Expect = 9e-05
Identities = 24/57 (42%), Positives = 32/57 (56%)
Frame = +1
Query: 79 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 249
T R + KN+ F+GLGNMG MA+NL+K G + +D SK A + A G T
Sbjct: 17 TLVRAMSTQGGAKNIGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGAT 73
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 62.5 bits (145), Expect = 1e-08
Identities = 31/65 (47%), Positives = 43/65 (66%)
Frame = +3
Query: 315 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 494
K V +YLG++G + + K GS+ ID +T P + K+I EKG+G DAPVSGG +GA
Sbjct: 69 KDVEQLYLGENGFLDNLKAGSVAIDMTTSSPALAKKIAEAGHEKGIGVLDAPVSGGDIGA 128
Query: 495 QNATL 509
+N TL
Sbjct: 129 KNGTL 133
Score = 38.3 bits (85), Expect = 0.22
Identities = 18/66 (27%), Positives = 32/66 (48%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG ++ F + P+ +++G+ G GSGQ K+ N + + + E +
Sbjct: 134 AIMVGGAEDVFLKVKPIFEILGSSVILQGDAGSGQHTKMVNQIAIASNMIGVTEAIIYAE 193
Query: 689 KMGLEP 706
+ GL P
Sbjct: 194 RAGLNP 199
>UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16;
Pezizomycotina|Rep: Predicted dehydrogenase -
Aspergillus oryzae
Length = 363
Score = 61.7 bits (143), Expect = 2e-08
Identities = 32/70 (45%), Positives = 43/70 (61%), Gaps = 3/70 (4%)
Frame = +2
Query: 509 AFMAGGRKEDFE---RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMN 679
+FM G + E R +L +MG K +H G G+G AKL NN L+ I +ATAE MN
Sbjct: 195 SFMFGASSQTGELVDRVQSVLMLMGKKAWHMGNSGTGVSAKLANNYLLAINNIATAEVMN 254
Query: 680 MGIKMGLEPK 709
+GI+ GL+PK
Sbjct: 255 LGIRCGLDPK 264
Score = 41.1 bits (92), Expect = 0.031
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +3
Query: 342 KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG-FTDAPVSGGVMGAQNATL 509
+ G + +K L ID+STIDP ++I G F DAP+SGGV+GA+ TL
Sbjct: 138 RHGELPALEKERLFIDTSTIDPASSREIANAIHTTRQGRFVDAPMSGGVVGARAGTL 194
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 61.3 bits (142), Expect = 3e-08
Identities = 31/66 (46%), Positives = 36/66 (54%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG KE FER L MG K H G G G + KL NNML+GI +A +E N K
Sbjct: 135 FMVGGDKEIFERCKNLFNSMGKKYLHVGDNGKGLIIKLINNMLLGINMIAASEACNFAEK 194
Query: 692 MGLEPK 709
G+ K
Sbjct: 195 TGINLK 200
Score = 59.7 bits (138), Expect = 8e-08
Identities = 30/63 (47%), Positives = 41/63 (65%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V +V DG++ AK G+++ID+STID N + A + L DAPVSGG++GAQN
Sbjct: 71 VSNVCDSSDGILKIAKAGTIIIDTSTIDANTSVLLAKKAKQNNLHMLDAPVSGGIIGAQN 130
Query: 501 ATL 509
ATL
Sbjct: 131 ATL 133
Score = 49.6 bits (113), Expect = 9e-05
Identities = 23/43 (53%), Positives = 28/43 (65%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
KN+AF+GLG MG MA NL+ G+ V G+D S D LN NG
Sbjct: 2 KNIAFIGLGCMGLHMAKNLIDNGYKVYGFDMSLDQLNKHQNNG 44
>UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Paracoccus denitrificans (strain Pd 1222)
Length = 309
Score = 61.3 bits (142), Expect = 3e-08
Identities = 35/91 (38%), Positives = 47/91 (51%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G + A GG +E ++R LP L+ M + + G IG+G +AKL NNM A
Sbjct: 126 GAASGQLAIWCGGEREVYDRCLPWLEKMADQPRYIGDIGAGTIAKLVNNMASTAIISVLA 185
Query: 668 ECMNMGIKMGLEPKFCWTC*TTHRLAPGRPR 760
E ++MG+K GLEP W T A GR R
Sbjct: 186 EALSMGVKAGLEPGPLWEAIRTG--AAGRMR 214
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/60 (40%), Positives = 32/60 (53%)
Frame = +3
Query: 339 GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLPSW 518
G G+V G++ +D ST +V +QI KG+ F DAPVSGG GA + L W
Sbjct: 76 GPRGLVEGMAPGTVWLDLSTNSVDVVRQIHAELAPKGIHFIDAPVSGGPAGAASGQLAIW 135
>UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 290
Score = 61.3 bits (142), Expect = 3e-08
Identities = 28/64 (43%), Positives = 38/64 (59%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
AFM GG + ER+ P+L M K HCG G+GQ AKL NNM++ + +A E +
Sbjct: 131 AFMVGGEDDAVERARPILDPMAGKIIHCGGSGTGQAAKLCNNMVLAVQQIAIGEAFVLAE 190
Query: 689 KMGL 700
K+GL
Sbjct: 191 KLGL 194
Score = 52.0 bits (119), Expect = 2e-05
Identities = 24/42 (57%), Positives = 29/42 (69%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 246
+AFLGLG+MGG MAANL G TVRG+DP + AA G+
Sbjct: 4 IAFLGLGHMGGPMAANLAAAGHTVRGFDPMPASREAAEAKGI 45
Score = 46.8 bits (106), Expect = 6e-04
Identities = 26/53 (49%), Positives = 32/53 (60%)
Frame = +3
Query: 351 VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
V+ A G+L ID+STI + + + ALEKG DAPVSGGV GA TL
Sbjct: 78 VLPAAPTGTLFIDTSTISVDDARTVHTQALEKGHAQLDAPVSGGVKGATAGTL 130
>UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB;
n=5; Mycobacterium|Rep: 3-hydroxyisobutyrate
dehydrogenase mmsB - Mycobacterium tuberculosis (strain
F11)
Length = 315
Score = 60.9 bits (141), Expect = 4e-08
Identities = 27/64 (42%), Positives = 39/64 (60%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
AFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM++ + +A AE +
Sbjct: 131 AFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAE 190
Query: 689 KMGL 700
K+GL
Sbjct: 191 KLGL 194
Score = 54.0 bits (124), Expect = 4e-06
Identities = 25/42 (59%), Positives = 31/42 (73%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 246
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGV 45
Score = 46.4 bits (105), Expect = 8e-04
Identities = 25/53 (47%), Positives = 33/53 (62%)
Frame = +3
Query: 351 VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
V+A A+ +L IDSSTI +++ +A G+ DAPVSGGV GA ATL
Sbjct: 78 VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATL 130
>UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=25; Bacteria|Rep: Probable
3-hydroxyisobutyrate dehydrogenase - Mycobacterium bovis
Length = 294
Score = 60.9 bits (141), Expect = 4e-08
Identities = 27/64 (42%), Positives = 39/64 (60%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
AFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM++ + +A AE +
Sbjct: 131 AFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAE 190
Query: 689 KMGL 700
K+GL
Sbjct: 191 KLGL 194
Score = 54.0 bits (124), Expect = 4e-06
Identities = 25/42 (59%), Positives = 31/42 (73%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 246
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGV 45
Score = 46.4 bits (105), Expect = 8e-04
Identities = 25/53 (47%), Positives = 33/53 (62%)
Frame = +3
Query: 351 VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
V+A A+ +L IDSSTI +++ +A G+ DAPVSGGV GA ATL
Sbjct: 78 VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATL 130
>UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 311
Score = 60.5 bits (140), Expect = 5e-08
Identities = 26/64 (40%), Positives = 39/64 (60%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG +E E + P L+ MG++ H G+ GSG KL NNM+ M +E + +G+K
Sbjct: 134 FMVGGSEEQLEYARPALQSMGSRIVHAGRFGSGTKLKLVNNMICATNLMVASEALTLGLK 193
Query: 692 MGLE 703
+GL+
Sbjct: 194 LGLD 197
Score = 42.7 bits (96), Expect = 0.010
Identities = 24/71 (33%), Positives = 39/71 (54%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L + V L VY G G+ + +LL++ ST+D +++ A G DAP++
Sbjct: 62 TMLPTPDVSLSVYEGAGGLFSITPPETLLLECSTVDVKTIERLGEGARASGTQLIDAPLT 121
Query: 477 GGVMGAQNATL 509
GG+ GA ATL
Sbjct: 122 GGIEGAALATL 132
Score = 33.5 bits (73), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
+ F+G G MG M +NL+K V D ++DA + A G T A L
Sbjct: 3 IGFIGAGRMGHRMISNLLKGSHAVLVLDGARDARDRVASLGATLAMNL 50
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 59.7 bits (138), Expect = 8e-08
Identities = 29/65 (44%), Positives = 42/65 (64%)
Frame = +3
Query: 315 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 494
K V +V+ +DGV A AK+GS+L+D +T P + +Q+ + G DAPVSGG +GA
Sbjct: 68 KDVEEVWTSEDGVFAGAKEGSILVDMTTSTPRLAEQLAQTGADLGFKVLDAPVSGGDIGA 127
Query: 495 QNATL 509
+N TL
Sbjct: 128 KNGTL 132
Score = 39.1 bits (87), Expect = 0.12
Identities = 20/65 (30%), Positives = 33/65 (50%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG ++ + P+L V+G + G G GQ K++NN+ + T + AE +
Sbjct: 133 AIMVGGEQQVLDEIKPVLSVIGQQIVFAGSAGKGQHMKMSNNIGVAATVITMAESLVYAK 192
Query: 689 KMGLE 703
GL+
Sbjct: 193 AAGLD 197
>UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 309
Score = 59.7 bits (138), Expect = 8e-08
Identities = 27/63 (42%), Positives = 44/63 (69%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V +VY G++G++ A+ G +L+D +T +P++ ++I A E+G DAPVSGG +GA+N
Sbjct: 83 VREVYFGRNGLLQAARPGIILVDMTTTEPSLAREIHQAAGEQGAFAVDAPVSGGDVGARN 142
Query: 501 ATL 509
A L
Sbjct: 143 AAL 145
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+ M GG +E + P+L+ MG + G GSGQ AK+ N +++ T + E + G
Sbjct: 146 SIMLGGDREVVDAIRPILEAMGKNLVYLGPAGSGQHAKVCNQIVITGTMIGVCESLMYGF 205
Query: 689 KMGLE 703
K GL+
Sbjct: 206 KAGLD 210
>UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Bacillus coagulans 36D1
Length = 294
Score = 59.3 bits (137), Expect = 1e-07
Identities = 27/65 (41%), Positives = 41/65 (63%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+AGGRKE+ + P+ +V+G H G+ G G AKL+ N+L+G+T +E + G K+
Sbjct: 140 LAGGRKEEIDAVRPMFEVLGKTIIHFGENGKGSAAKLSINLLLGLTIEGASEAILFGEKL 199
Query: 695 GLEPK 709
GLE K
Sbjct: 200 GLEKK 204
Score = 48.0 bits (109), Expect = 3e-04
Identities = 27/71 (38%), Positives = 39/71 (54%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++LT+ V +V G+DGV+A KG ++D ST+ P+ + EK F DAPVS
Sbjct: 67 TMLTNAAAVENVLQGEDGVLAGLTKGKTVVDMSTVSPSDSIRFAKWVEEKRGHFIDAPVS 126
Query: 477 GGVMGAQNATL 509
G V A+ L
Sbjct: 127 GSVQPAKEGNL 137
>UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to MGC108315 protein - Nasonia vitripennis
Length = 276
Score = 58.8 bits (136), Expect = 1e-07
Identities = 25/47 (53%), Positives = 36/47 (76%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIA 437
++L N+ VLD Y GKDG+++ AKKG+ L+DSSTIDP+V + +F A
Sbjct: 86 TMLPMNQHVLDTYTGKDGIISSAKKGTFLVDSSTIDPSVSQTVFKAA 132
Score = 54.8 bits (126), Expect = 2e-06
Identities = 22/44 (50%), Positives = 32/44 (72%)
Frame = +2
Query: 578 KQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 709
K HCG G GQVAK+ NNML+ I+ + +E +++G K+GL+PK
Sbjct: 134 KAVHCGDTGMGQVAKICNNMLLAISMIGVSEALSLGEKLGLDPK 177
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/61 (42%), Positives = 35/61 (57%)
Frame = +1
Query: 73 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 252
+YT R NV F+GLGNMGGFMA NL+KKG+ + +D +K A++ G
Sbjct: 13 IYTVGR--VGQRDFSNVGFVGLGNMGGFMAKNLLKKGYKLTVFDINKTAIDNVVSAGAKG 70
Query: 253 A 255
A
Sbjct: 71 A 71
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 58.8 bits (136), Expect = 1e-07
Identities = 29/65 (44%), Positives = 45/65 (69%)
Frame = +3
Query: 315 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 494
K V +VY G++G++ +AKK S +ID +T P + +I+ A ++ + DAPVSGG +GA
Sbjct: 69 KDVEEVYFGENGILENAKKESCIIDMTTTSPKLSIKIYNEAKKREIYALDAPVSGGDVGA 128
Query: 495 QNATL 509
+NATL
Sbjct: 129 KNATL 133
Score = 36.3 bits (80), Expect = 0.88
Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 4/45 (8%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSK----DALNAAAK 237
K + F+G+G MG M NL+KKG+ V Y +K D +N AK
Sbjct: 2 KTIGFIGVGVMGKSMVRNLMKKGYEVSIYTRTKEKVLDVINEGAK 46
Score = 33.5 bits (73), Expect = 6.2
Identities = 17/65 (26%), Positives = 30/65 (46%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+ M GG E FE+ +L +G + G+ G+GQ K+ N + + E +
Sbjct: 134 SIMVGGDLEVFEKHKDVLSALGTNIIYEGKAGNGQHTKMANQIALAGAIAGVCEAITYAK 193
Query: 689 KMGLE 703
+GL+
Sbjct: 194 GVGLD 198
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 58.0 bits (134), Expect = 3e-07
Identities = 28/65 (43%), Positives = 39/65 (60%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG++E FE P L+ K + GQ GSGQ+ KL N +L I A AE + M +K+
Sbjct: 134 MCGGKQELFENVKPYLQCFADKILYMGQPGSGQLTKLINQLLFDINVAALAEILPMSVKL 193
Query: 695 GLEPK 709
GL+P+
Sbjct: 194 GLDPE 198
Score = 42.7 bits (96), Expect = 0.010
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L +++VV V LG+ G+ + G +++D+STI+ + +I G+ F DAPVSG
Sbjct: 63 LPNSEVVCQVVLGETGLKKVLRAGQIIVDTSTINYSTTLEIGKQLESVGVEFIDAPVSGM 122
Query: 483 VMGAQNATL 509
A+ TL
Sbjct: 123 ESRAKEGTL 131
>UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 297
Score = 58.0 bits (134), Expect = 3e-07
Identities = 27/59 (45%), Positives = 39/59 (66%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 479
L + +V DVYLGK G+VA A+ GS LI++STIDPN +++ A + G+ D +SG
Sbjct: 65 LPNPPIVRDVYLGKQGLVAQARPGSTLIETSTIDPNTIREVAQAATKSGIRILDIALSG 123
Score = 47.6 bits (108), Expect = 4e-04
Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML-MGITGMATAECMNMGI 688
F GG E ++ L LL+V+ K G IG+ + KL NN++ +G +A AE +G+
Sbjct: 135 FQVGGPDELIDQHLELLQVLAKKINRTGGIGTAKTVKLVNNLMSLGNVAVA-AEAFVLGV 193
Query: 689 KMGLEPK 709
K G+EPK
Sbjct: 194 KCGMEPK 200
Score = 41.5 bits (93), Expect = 0.023
Identities = 19/43 (44%), Positives = 27/43 (62%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
K + +GLGN+GG M L+ +G V G+D S A AAA++G
Sbjct: 2 KEIGLIGLGNIGGGMCRRLLDRGIGVVGFDLSPAATKAAAEHG 44
>UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:
Probable - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 295
Score = 57.6 bits (133), Expect = 3e-07
Identities = 28/60 (46%), Positives = 38/60 (63%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L + +V G GV A A+ G+L+ID S+IDPN KQ+ A EKGL + D+P+SGG
Sbjct: 66 LNAPAIVRQAVFGDAGVAAGAQAGTLIIDMSSIDPNATKQLAADAAEKGLRWVDSPLSGG 125
Score = 46.4 bits (105), Expect = 8e-04
Identities = 20/63 (31%), Positives = 36/63 (57%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
MAGG +D + + +L+ + + H G +G+GQ KL N +L G+ +A AE + +
Sbjct: 137 MAGGTAQDVKDAHAVLRHVASNYTHMGSVGAGQTTKLINQVLCGLGFLAVAEATQLALDA 196
Query: 695 GLE 703
G++
Sbjct: 197 GVD 199
Score = 34.7 bits (76), Expect = 2.7
Identities = 17/45 (37%), Positives = 23/45 (51%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
VA +G G MGG + A LV+ G + +DP D + A G A
Sbjct: 5 VALIGAGAMGGSIGARLVETGNRLTVFDPGPDKVQALVDKGAFAA 49
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 57.6 bits (133), Expect = 3e-07
Identities = 29/71 (40%), Positives = 46/71 (64%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
SI+ + V ++YL +DG++A A G+++ID +T P + +I A + GL DAPV+
Sbjct: 64 SIVGYPQDVEEIYLAEDGILASANPGTIVIDMTTSSPALAIRIAEQAAQTGLHALDAPVT 123
Query: 477 GGVMGAQNATL 509
GG +GA+N TL
Sbjct: 124 GGDLGAKNGTL 134
Score = 41.9 bits (94), Expect = 0.018
Identities = 22/66 (33%), Positives = 33/66 (50%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A + GG + F+ PL + MG G G GQ AKL N + + + + TAE +
Sbjct: 135 AILVGGEEAAFDTVKPLFEAMGKSIARFGGPGQGQSAKLANQIAIAGSMIGTAEMLLFVT 194
Query: 689 KMGLEP 706
K G++P
Sbjct: 195 KSGIDP 200
Score = 41.5 bits (93), Expect = 0.023
Identities = 17/34 (50%), Positives = 25/34 (73%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD 216
K + F+GLG MG M NL+K GF+V+GY+ +K+
Sbjct: 3 KTIGFIGLGVMGQGMVRNLLKAGFSVKGYNRTKE 36
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/63 (41%), Positives = 41/63 (65%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V VY G+ G++ +A+ G+ +ID +T P + + I+ A +KG+ DAPVSGG +GA+
Sbjct: 71 VEQVYFGEGGILENARPGTYVIDMTTSTPTLAQSIYEAAKQKGIHALDAPVSGGDIGARE 130
Query: 501 ATL 509
TL
Sbjct: 131 GTL 133
Score = 36.7 bits (81), Expect = 0.66
Identities = 20/73 (27%), Positives = 32/73 (43%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G E M GG ++ F P+L+ +G G G+GQ K+ N + + +
Sbjct: 127 GAREGTLTIMVGGDEDVFLACKPILERLGTNIVRQGGAGAGQHTKMCNQIAIATNMIGVC 186
Query: 668 ECMNMGIKMGLEP 706
E M + GL+P
Sbjct: 187 EAMAYAKRAGLDP 199
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 57.2 bits (132), Expect = 4e-07
Identities = 29/60 (48%), Positives = 36/60 (60%)
Frame = +3
Query: 330 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
V G+DGV H G+L+ID S+I P+V + A E+G DAPVSGG GA NA L
Sbjct: 74 VLTGEDGVFEHTPSGALIIDFSSIRPDVTTALAAQATERGFRLIDAPVSGGEAGAVNAAL 133
Score = 44.0 bits (99), Expect = 0.004
Identities = 19/45 (42%), Positives = 26/45 (57%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 643
+ M GG EDFE + P+L V+G H G GSGQ K N +++
Sbjct: 134 SIMVGGAPEDFESARPILDVVGKTVVHVGPNGSGQTVKAANQLIV 178
Score = 38.7 bits (86), Expect = 0.16
Identities = 21/45 (46%), Positives = 25/45 (55%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
+AF+GLG MG MA NL K G V GY+ D A + G T A
Sbjct: 4 IAFIGLGIMGSPMACNLAKAGHQVVGYNLIPDRTAALVEAGGTAA 48
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 57.2 bits (132), Expect = 4e-07
Identities = 24/65 (36%), Positives = 39/65 (60%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M G + FE+ P+L V+G +H G G+G K+ NN+L+G + AE + +G+K
Sbjct: 139 MVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCNMASLAEALVLGVKC 198
Query: 695 GLEPK 709
GL+P+
Sbjct: 199 GLKPE 203
Score = 56.4 bits (130), Expect = 8e-07
Identities = 25/64 (39%), Positives = 41/64 (64%)
Frame = +3
Query: 318 VVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQ 497
+V V G GV++ K G++++D S++ P+ ++ +A EKG+ + DAPVSGG GA+
Sbjct: 73 IVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSGGTKGAE 132
Query: 498 NATL 509
TL
Sbjct: 133 AGTL 136
Score = 35.1 bits (77), Expect = 2.0
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
+ F+GLG MG MA NL+K+G TV +D + + A G
Sbjct: 7 IGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQG 47
>UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 316
Score = 57.2 bits (132), Expect = 4e-07
Identities = 28/67 (41%), Positives = 43/67 (64%), Gaps = 1/67 (1%)
Frame = +2
Query: 512 FMAGGR-KEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
FM G KE F+ LL+ MG +C + G+G +AK+ NNM +GI +A AE +++G
Sbjct: 151 FMVGAENKELFQECKNLLQHMGKNIANCEKPGAGSIAKICNNMALGIEMIAVAEAISLGK 210
Query: 689 KMGLEPK 709
K+G++PK
Sbjct: 211 KLGIDPK 217
Score = 48.8 bits (111), Expect = 2e-04
Identities = 24/45 (53%), Positives = 31/45 (68%), Gaps = 1/45 (2%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKK-GFTVRGYDPSKDALNAAAKNGV 246
+ V F+GLGNMGG MA NL +K GF V +D +KD+L AK G+
Sbjct: 17 ETVGFIGLGNMGGPMALNLARKGGFEVIAFDVNKDSLKKYAKEGL 61
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/71 (38%), Positives = 40/71 (56%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L ++ V V G++G+ + K SL IDSSTI + +I+ A + + DAPVS
Sbjct: 79 TMLPNSSHVSSVLEGENGLFQKSAKNSLFIDSSTISYHAAIKIYENAKKVNQRYIDAPVS 138
Query: 477 GGVMGAQNATL 509
GGV A TL
Sbjct: 139 GGVGAATAGTL 149
>UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 366
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
Frame = +2
Query: 509 AFMAGGRKED-FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMG 685
+FM G F + P L +MG++ HCG+ G+G +AK+ NN+L+GI+ + E M +G
Sbjct: 186 SFMVGSDSSTTFASAEPYLSLMGSRAVHCGKNGNGLIAKIANNLLLGISMLGVTEAMLLG 245
Query: 686 IKMGLEP 706
GL P
Sbjct: 246 TAHGLPP 252
Score = 37.5 bits (83), Expect = 0.38
Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Frame = +3
Query: 297 SILTSNKVVLD-VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQ----IFPIALEKGLGFT 461
S+ T +LD + + V A+ +L ID +T+DP+V Q I
Sbjct: 110 SVYTHENGILDGLESFQAAAVDDAQAKTLCIDCTTLDPDVAVQTATAIKNANANGAFDMI 169
Query: 462 DAPVSGGVMGAQNATL 509
DAPVSGGV+GA ATL
Sbjct: 170 DAPVSGGVVGANAATL 185
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 56.8 bits (131), Expect = 6e-07
Identities = 25/67 (37%), Positives = 40/67 (59%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
AFMAGG++E +++ P +MG+ G GSG V KLTN +++ +T A +E +
Sbjct: 132 AFMAGGKEEIYKKVEPFFNIMGSSSILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAA 191
Query: 689 KMGLEPK 709
K G +P+
Sbjct: 192 KAGADPE 198
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/71 (35%), Positives = 39/71 (54%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
+IL + +V D+ G DG+ K+GS+++D S++ P + GL F D+PVS
Sbjct: 61 TILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTPTESILCANKLKDMGLEFIDSPVS 120
Query: 477 GGVMGAQNATL 509
GG A + TL
Sbjct: 121 GGEPKAIDGTL 131
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 56.8 bits (131), Expect = 6e-07
Identities = 25/63 (39%), Positives = 42/63 (66%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V++VY G+ GV++ A++G + +D +T+ P + + A E+G+ + DAPVSGG GA+
Sbjct: 71 VINVYTGEGGVLSAARRGVICLDFTTVGPKTSRFVAGRAGERGVAYLDAPVSGGPEGAEQ 130
Query: 501 ATL 509
TL
Sbjct: 131 GTL 133
Score = 50.8 bits (116), Expect = 4e-05
Identities = 25/72 (34%), Positives = 38/72 (52%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G + M GG + +ER PLL V+G + G+ G+G AK+ N L+ + +A A
Sbjct: 127 GAEQGTLTIMVGGDQAAWERVRPLLSVLGKTVEYLGESGAGSAAKILNQYLVAVHSVAAA 186
Query: 668 ECMNMGIKMGLE 703
E M G+ GL+
Sbjct: 187 EAMVAGVAYGLD 198
>UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 305
Score = 56.8 bits (131), Expect = 6e-07
Identities = 27/65 (41%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITGMATAECMNMG 685
+ +A G K+ FE++LP+L+ + FHCG+ +G+GQ K NNM+ +AT E + MG
Sbjct: 132 SIIASGPKDAFEKTLPVLQSISPNVFHCGERVGNGQTMKTVNNMMNVSCRLATLEVVAMG 191
Query: 686 IKMGL 700
K GL
Sbjct: 192 RKFGL 196
>UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidothermus cellulolyticus
11B|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidothermus cellulolyticus (strain ATCC
43068 / 11B)
Length = 305
Score = 56.4 bits (130), Expect = 8e-07
Identities = 29/69 (42%), Positives = 39/69 (56%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L + V DV+LG DGVVA A+ G ++ + ST++P V + I P KG D PVSG
Sbjct: 66 LADRRAVEDVFLGPDGVVAGARPGLVVAELSTVEPEVARAIAPELRAKGADILDVPVSGS 125
Query: 483 VMGAQNATL 509
V A+ L
Sbjct: 126 VAVAREGGL 134
Score = 38.7 bits (86), Expect = 0.16
Identities = 19/62 (30%), Positives = 31/62 (50%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG + P+L ++G + FH G +GSG KL N ++ A AE + + +
Sbjct: 137 MVGGEDASLDAIRPVLDIIGRRIFHLGPLGSGAAMKLAVNTVIHGLNAALAEGLVLAERA 196
Query: 695 GL 700
G+
Sbjct: 197 GI 198
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 56.0 bits (129), Expect = 1e-06
Identities = 25/67 (37%), Positives = 35/67 (52%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ GG ER P+L+ M A+ H G GSG V KL NN L + TAE + + +
Sbjct: 143 LLGGESATIERLAPMLEAMSARHTHVGPAGSGHVVKLANNYLCAAHLLTTAEAVTLAARA 202
Query: 695 GLEPKFC 715
G++P C
Sbjct: 203 GVDPAAC 209
Score = 52.8 bits (121), Expect = 9e-06
Identities = 27/69 (39%), Positives = 42/69 (60%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L ++ V +V G++ A KGS+++D+ST DP V +++ +E GL + DAPVSGG
Sbjct: 72 LPTSAHVREVIETSPGLLQRAPKGSVIVDTSTSDPAVTRELAGKVVEAGLEWLDAPVSGG 131
Query: 483 VMGAQNATL 509
GA + L
Sbjct: 132 PAGAASGAL 140
Score = 39.9 bits (89), Expect = 0.071
Identities = 20/46 (43%), Positives = 26/46 (56%)
Frame = +1
Query: 112 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 249
D N+ +GLG MGG MA L GFTV G D + A + A G++
Sbjct: 10 DMNIVVIGLGQMGGNMAMTLHAAGFTVTGTDVADAARDNLAARGLS 55
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 56.0 bits (129), Expect = 1e-06
Identities = 28/71 (39%), Positives = 45/71 (63%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
SI+ K V +VY G G++++A+ G+L++D +T P + ++I+ KGL DAPV+
Sbjct: 97 SIVGYPKDVEEVYFGDGGIISNAQPGALIVDMTTSSPALAERIWEAGKAKGLRPLDAPVT 156
Query: 477 GGVMGAQNATL 509
GG GA+ TL
Sbjct: 157 GGDTGAKAGTL 167
Score = 43.2 bits (97), Expect = 0.008
Identities = 22/55 (40%), Positives = 29/55 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAEC 673
+ + GG K DF+ LPL + MG H G G+GQ AKL N + I G + C
Sbjct: 168 SILVGGDKVDFDACLPLFQAMGKIIVHMGSAGAGQHAKLANQ--IAIAGALSGVC 220
>UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella parapertussis
Length = 296
Score = 55.6 bits (128), Expect = 1e-06
Identities = 25/62 (40%), Positives = 35/62 (56%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG D E PL++ MG + FHCG +GS ++AK+ NNML TAE + +
Sbjct: 140 MMGGETADVEAVRPLMQAMGERLFHCGALGSAEIAKVINNMLCVANMFLTAEAIELAESH 199
Query: 695 GL 700
G+
Sbjct: 200 GV 201
Score = 37.1 bits (82), Expect = 0.50
Identities = 20/44 (45%), Positives = 26/44 (59%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 246
K VAF+G+GNMG MA + GF + D + D L A A+ GV
Sbjct: 5 KTVAFIGVGNMGAPMARCARRAGFELIVCDRNPDVLAAFAQEGV 48
Score = 33.9 bits (74), Expect = 4.7
Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Frame = +3
Query: 300 ILTSNKVVLDVYLGKDGVVAHAKKGS--LLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 473
+L ++ +++ LG G+ G ++ ST P+ + + G DAPV
Sbjct: 66 LLANDAQIMETMLGGQGLAQAVPAGHRPIVCMMSTTLPDTLRALEAPLAAVGARLVDAPV 125
Query: 474 SGGVMGAQNATL 509
SGG++GA+ TL
Sbjct: 126 SGGIVGAEAGTL 137
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 55.2 bits (127), Expect = 2e-06
Identities = 28/69 (40%), Positives = 36/69 (52%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L S +V D GK+GV+ H + G L+D ST D + A KG+ + D PVSGG
Sbjct: 65 LPSPNIVADTVAGKEGVLCHLQTGGFLLDLSTTDVQTTLAMEKAAAAKGIYYLDCPVSGG 124
Query: 483 VMGAQNATL 509
GA TL
Sbjct: 125 PAGADAGTL 133
Score = 40.7 bits (91), Expect = 0.041
Identities = 21/47 (44%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM-GIT 652
M GG K+ + PLL ++G + G G+GQ KL NNML+ GIT
Sbjct: 136 MVGGDKQAYFSVKPLLDILGDTILYVGDSGAGQTVKLCNNMLVAGIT 182
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/67 (35%), Positives = 40/67 (59%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+ + G D R++P+L+ M + H GQ G+G VAK+ NNML ++TAE + M
Sbjct: 135 SMVIGAEDADLARAMPVLEGMSGTRVHVGQCGAGNVAKIANNMLAACHLISTAEAVAMAA 194
Query: 689 KMGLEPK 709
+ G++P+
Sbjct: 195 RAGVDPE 201
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/47 (53%), Positives = 28/47 (59%)
Frame = +1
Query: 130 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQ 270
+GLGNMGG MAA L KGF V G+D S+ AL A GV P Q
Sbjct: 8 IGLGNMGGGMAATLAGKGFDVSGFDLSQAALAQAESKGVKPVADRTQ 54
Score = 46.4 bits (105), Expect = 8e-04
Identities = 21/63 (33%), Positives = 36/63 (57%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V V LG G+ +KG +++D++T P + +++ + G+ F DAPVSGG GA
Sbjct: 72 VESVCLGAGGINEVGRKGLIVVDTTTSTPEMSRKVAAELAKNGIAFIDAPVSGGPKGAAT 131
Query: 501 ATL 509
++
Sbjct: 132 GSM 134
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/53 (49%), Positives = 33/53 (62%)
Frame = +1
Query: 106 NTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
NT +A +GLG MGG MAA L K G+ V G+DPS+ A AAA+ G+ L
Sbjct: 2 NTSTRIAVIGLGAMGGAMAATLHKAGWDVTGFDPSEAARTAAAQTGIATTASL 54
Score = 40.3 bits (90), Expect = 0.054
Identities = 19/46 (41%), Positives = 30/46 (65%)
Frame = +3
Query: 381 LIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLPSW 518
+ID++T +P KQ+ +A +G F DAPVSGG GA + +L ++
Sbjct: 89 IIDTTTSEPATSKQMAHLADTQGAAFVDAPVSGGRDGAASGSLSAF 134
Score = 38.3 bits (85), Expect = 0.22
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Frame = +2
Query: 479 RSHGCSERYPAFMAGGRKEDFERSLP-LLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 655
R S AF+ GG + P LL + G K H G GSG V KL NN+L
Sbjct: 123 RDGAASGSLSAFV-GGTDAALAAAEPVLLALTGGKYSHIGGPGSGNVVKLLNNVLAAANL 181
Query: 656 MATAECMNMGIKMGLEP 706
++ E + + G++P
Sbjct: 182 VSVGEALGVAKAYGIDP 198
>UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.35 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 387
Score = 54.4 bits (125), Expect = 3e-06
Identities = 24/65 (36%), Positives = 40/65 (61%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
F+ G K +E++ P L +MG +F+ G++G+G KL NM+MG + AE + + K
Sbjct: 229 FLTAGDKPLYEKAAPFLDIMGKSKFYLGEVGNGAAMKLVVNMIMGSMMASFAEGILLSQK 288
Query: 692 MGLEP 706
+GL+P
Sbjct: 289 VGLDP 293
Score = 33.5 bits (73), Expect = 6.2
Identities = 20/62 (32%), Positives = 29/62 (46%)
Frame = +3
Query: 324 LDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNA 503
+DV GK+G + G +D ST+D I + G F +APVSG A++
Sbjct: 166 IDVACGKNGAIFGISSGKGYVDVSTVDVASSILISKQIKDTGALFLEAPVSGSKKPAEDG 225
Query: 504 TL 509
L
Sbjct: 226 QL 227
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/71 (39%), Positives = 41/71 (57%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S++T V +V G++GVV K+G + +D ST P K++ E G+ F DAPV+
Sbjct: 62 SMVTDAPDVEEVLFGENGVVKSNKRGLIFVDMSTNSPEFAKKVTKRLSEYGMEFLDAPVT 121
Query: 477 GGVMGAQNATL 509
GG GA+ TL
Sbjct: 122 GGDKGAREGTL 132
Score = 50.8 bits (116), Expect = 4e-05
Identities = 22/72 (30%), Positives = 39/72 (54%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G E M GG+++ F+R P+ K MG H G +GSGQ KL N +++ + ++
Sbjct: 126 GAREGTLTIMVGGKEDVFKRVEPIFKAMGKNIIHVGDVGSGQALKLCNQVVVALNMVSVV 185
Query: 668 ECMNMGIKMGLE 703
E + + +G++
Sbjct: 186 EGLLLARSLGID 197
>UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=16; Gammaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 298
Score = 54.0 bits (124), Expect = 4e-06
Identities = 25/70 (35%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVSG 479
L + +VV +V G G+ A+ G LL+D S+++P +++ +A +G+ + DAPVSG
Sbjct: 69 LANTEVVREVVFGPQGIAQGARAGQLLLDLSSLEPTATREMAAELAASRGVAWVDAPVSG 128
Query: 480 GVMGAQNATL 509
G GA+ +L
Sbjct: 129 GTPGAEAGSL 138
Score = 50.8 bits (116), Expect = 4e-05
Identities = 22/67 (32%), Positives = 36/67 (53%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG D ER P+L +G + H G +G+GQV K N M++ + AE + +
Sbjct: 139 AIMVGGEATDVERVRPVLLTLGQRVTHMGAVGAGQVTKACNQMIVACNALVIAEVVALAE 198
Query: 689 KMGLEPK 709
+ G++ +
Sbjct: 199 RSGVDAR 205
>UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: 3-hydroxyisobutyrate dehydrogenase precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 301
Score = 54.0 bits (124), Expect = 4e-06
Identities = 26/65 (40%), Positives = 35/65 (53%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG FER +L+V+G + G GSG V KL NN+ + I MA E + G+
Sbjct: 137 AIMVGGEPSTFERCQAVLEVLGGAVSYIGASGSGSVVKLCNNLAISIIAMANIEALAFGV 196
Query: 689 KMGLE 703
G+E
Sbjct: 197 ANGVE 201
Score = 39.9 bits (89), Expect = 0.071
Identities = 22/58 (37%), Positives = 28/58 (48%)
Frame = +3
Query: 336 LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
LG +G GS+ ID STI P + I E+ + DAPVSGG A+ L
Sbjct: 79 LGTNGAAYGMAAGSICIDMSTIAPTASRAIAAKLAERQIAMLDAPVSGGPARAKTGEL 136
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 54.0 bits (124), Expect = 4e-06
Identities = 29/63 (46%), Positives = 37/63 (58%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V V LG+ GV+ A+ GSL+ID STI P ++I E+ + DAPVSGG GA
Sbjct: 74 VEQVLLGEGGVIHGARPGSLVIDMSTISPRATQRIAAHLAERHIHMLDAPVSGGSEGAAR 133
Query: 501 ATL 509
TL
Sbjct: 134 GTL 136
Score = 48.8 bits (111), Expect = 2e-04
Identities = 24/65 (36%), Positives = 35/65 (53%)
Frame = +2
Query: 482 SHGCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 661
S G + + M GG FER+LP+ + MG H G IG+GQ KL N +L+ +A
Sbjct: 128 SEGAARGTLSIMVGGDVTQFERALPVFQAMGTTITHLGPIGAGQTTKLVNQILVVGHALA 187
Query: 662 TAECM 676
+E +
Sbjct: 188 MSEAL 192
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 54.0 bits (124), Expect = 4e-06
Identities = 29/70 (41%), Positives = 46/70 (65%), Gaps = 1/70 (1%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIF-PIALEKGLGFTDAPVSG 479
L+ + V++V G +GV A +G++ +D+STI P+V ++I + EK + DAPVSG
Sbjct: 64 LSDSPDVMEVVFGPNGVAAGICEGAIFVDNSTIKPSVAQEIARRLWKEKKVRALDAPVSG 123
Query: 480 GVMGAQNATL 509
G +GA+N TL
Sbjct: 124 GDIGARNGTL 133
Score = 37.5 bits (83), Expect = 0.38
Identities = 20/62 (32%), Positives = 29/62 (46%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG LP+L +G K H G G+GQV K N +++ +A E + K
Sbjct: 136 MVGGDAAALATVLPVLLAVGKKVTHIGDCGAGQVCKAANQIMVAAQMVALGEILVFCEKC 195
Query: 695 GL 700
G+
Sbjct: 196 GV 197
>UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 54.0 bits (124), Expect = 4e-06
Identities = 32/75 (42%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Frame = +2
Query: 488 GCSERYPAFMAGGR-KEDFERSLPLLKVMGAKQ--FHCGQIGSGQVAKLTNNMLMGITGM 658
G + AFMAG K F R L MG F CG IG+G K+ NN L IT +
Sbjct: 150 GAQDGTLAFMAGANNKAIFPRVKGYLSHMGKPDAIFLCGDIGAGTAFKVINNYLSAITSL 209
Query: 659 ATAECMNMGIKMGLE 703
A +E +N+G KMGL+
Sbjct: 210 AASEALNIGTKMGLD 224
Score = 37.1 bits (82), Expect = 0.50
Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 11/82 (13%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKD-GVVAHAKKGS------LLIDSSTIDPN----VPKQIFPIALE 443
++L + V VYL G++A A+ S L+++ TI+ + V K
Sbjct: 75 TMLPDSNAVKKVYLDPSTGILAGAEANSGTKSDKLIMECGTIETSTILEVAKATSSSKAA 134
Query: 444 KGLGFTDAPVSGGVMGAQNATL 509
+ L F DAPVSGG MGAQ+ TL
Sbjct: 135 ENLTFVDAPVSGGPMGAQDGTL 156
>UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=13;
Magnoliophyta|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 347
Score = 54.0 bits (124), Expect = 4e-06
Identities = 21/63 (33%), Positives = 39/63 (61%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG ++ + + P+L+ MG +CG G+G AK+ NN+ M ++ + T+E + +G
Sbjct: 183 FMVGGPEDAYLAARPILQSMGRTSIYCGGSGNGSAAKICNNLAMAVSMLGTSEALALGQS 242
Query: 692 MGL 700
+G+
Sbjct: 243 LGI 245
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/59 (35%), Positives = 36/59 (61%)
Frame = +1
Query: 73 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 249
L+ + + +SN +NV F+GLGNMG M NL++ G+ V +D ++D + + GV+
Sbjct: 24 LHRFSSSSQNSNQFQNVGFIGLGNMGFRMVNNLIRAGYKVTVHDINRDVMKMFTEMGVS 82
Score = 41.9 bits (94), Expect = 0.018
Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 12/83 (14%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAK--KGSLLIDSSTIDPNVPKQIFPIALEKGLG----- 455
++L S+ V+DVY G +G++ + +L IDSSTIDP ++I L
Sbjct: 99 TMLPSSSHVMDVYTGTNGLLLGENDIRPALFIDSSTIDPQTTRKISLAVSNCNLKEKRDN 158
Query: 456 -----FTDAPVSGGVMGAQNATL 509
DAPVSGGV+ A+ TL
Sbjct: 159 WEKPVMLDAPVSGGVLAAEAGTL 181
>UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=11;
Betaproteobacteria|Rep: 2-hydroxy-3-oxopropionate
reductase - Ralstonia solanacearum UW551
Length = 298
Score = 53.6 bits (123), Expect = 5e-06
Identities = 34/73 (46%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKG----SLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 470
+TS V V LG DGV+ A +G ++ ID STI ++I GL F DAP
Sbjct: 65 VTSTADVEAVLLGPDGVIHGAPRGKPGSAVCIDHSTISAVATRRIAAELETAGLDFLDAP 124
Query: 471 VSGGVMGAQNATL 509
VSGG MGAQ ATL
Sbjct: 125 VSGGTMGAQKATL 137
Score = 48.8 bits (111), Expect = 2e-04
Identities = 26/73 (35%), Positives = 36/73 (49%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G + + M GG+ E ER PLL+++G H G G+GQVAK N ++ I A
Sbjct: 131 GAQKATLSIMVGGKAEVLERVRPLLQLLGTTITHIGDHGAGQVAKACNQIVQVINIQGIA 190
Query: 668 ECMNMGIKMGLEP 706
E M G +P
Sbjct: 191 EAMLFARAQGTDP 203
Score = 38.7 bits (86), Expect = 0.16
Identities = 19/44 (43%), Positives = 24/44 (54%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 252
+AF+GLGNMG M +LV G VR Y +A + A G P
Sbjct: 4 IAFIGLGNMGSPMVGHLVAAGHAVRAYVRRPEAADRARALGAEP 47
>UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Lyngbya sp. PCC 8106
Length = 371
Score = 53.6 bits (123), Expect = 5e-06
Identities = 24/70 (34%), Positives = 40/70 (57%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A +A G + FER PLL++M + +CG+IGSG KL +N + + A +E + +G+
Sbjct: 153 AVLASGSRATFERVEPLLQLMADQVLYCGEIGSGTRCKLIHNAVNAVAVQAVSEGITLGL 212
Query: 689 KMGLEPKFCW 718
G+ + W
Sbjct: 213 AQGISLETIW 222
>UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Arthrobacter|Rep: 2-hydroxy-3-oxopropionate reductase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 53.6 bits (123), Expect = 5e-06
Identities = 25/72 (34%), Positives = 38/72 (52%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G + A M G ++DF+R LPL MG G +GSG +AK N +++G T A A
Sbjct: 145 GAEDGTLAIMVGAGEQDFQRLLPLFNAMGGTVRRLGPLGSGSLAKACNQLIVGTTTAALA 204
Query: 668 ECMNMGIKMGLE 703
E + + G++
Sbjct: 205 EAAELAERSGMD 216
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/48 (50%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDAL-NAAAKNGVTPA 255
K F+GLG MGG MAANL+K G+ V G++ S AL + AA+ G+ A
Sbjct: 16 KRAGFVGLGLMGGPMAANLLKAGWNVTGWNRSAAALDDLAARGGMRAA 63
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 53.2 bits (122), Expect = 7e-06
Identities = 26/67 (38%), Positives = 37/67 (55%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG+ E FER P+L MGA G +G+G V KL N +++ A E + +
Sbjct: 134 AIMVGGKPEVFERVQPVLAKMGASVTLTGAVGAGNVTKLANQIMVACNIAAMGEALVLAT 193
Query: 689 KMGLEPK 709
K GL+P+
Sbjct: 194 KAGLDPE 200
Score = 50.4 bits (115), Expect = 5e-05
Identities = 27/71 (38%), Positives = 40/71 (56%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L V LG GV+ AK G++++D S+I P V +++ KG+ F DAPVS
Sbjct: 63 TMLPDGPEVETAVLGPGGVLEGAKAGTVVVDMSSISPMVSQKVAAACAAKGVEFLDAPVS 122
Query: 477 GGVMGAQNATL 509
GG A + TL
Sbjct: 123 GGEPKAIDGTL 133
>UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 334
Score = 53.2 bits (122), Expect = 7e-06
Identities = 27/69 (39%), Positives = 41/69 (59%), Gaps = 3/69 (4%)
Frame = +2
Query: 512 FMAGGRKED---FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNM 682
FM G K+ +++ LLK+MG + +CG G G AKL NN L+ +T +ATAE ++
Sbjct: 168 FMVGCNKDKQQVYKQVEELLKLMGGRIVNCGTQGQGLAAKLANNYLLAVTNVATAEAFHL 227
Query: 683 GIKMGLEPK 709
K+G + K
Sbjct: 228 AEKLGCDLK 236
Score = 39.5 bits (88), Expect = 0.094
Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Frame = +3
Query: 366 KKGSLLIDSSTIDPNVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATL 509
K + +D STID + + +K F DAPVSGGV+GA+ TL
Sbjct: 117 KTSKIFVDCSTIDTQTSIECGKLVTDKDASAAFVDAPVSGGVVGAEKGTL 166
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 53.2 bits (122), Expect = 7e-06
Identities = 28/71 (39%), Positives = 44/71 (61%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L ++ V +V LG++G++ AK G++LID S+I P ++I KG+ DAPVS
Sbjct: 62 TMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVS 121
Query: 477 GGVMGAQNATL 509
GG A + TL
Sbjct: 122 GGEPKAIDGTL 132
Score = 51.2 bits (117), Expect = 3e-05
Identities = 22/64 (34%), Positives = 35/64 (54%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG K F++ L+K M H G+IG+G V KL N +++ + A +E + + K
Sbjct: 135 MVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKA 194
Query: 695 GLEP 706
G+ P
Sbjct: 195 GVNP 198
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 52.8 bits (121), Expect = 9e-06
Identities = 25/65 (38%), Positives = 37/65 (56%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
MAGG +D +++ P+L MG + F G IGSG K NN + G +A E + +G
Sbjct: 140 MAGGASDDIDQADPILCAMGGQIFRTGPIGSGHAMKAINNFVSGAGVLAAIEGVLLGRTF 199
Query: 695 GLEPK 709
GL+P+
Sbjct: 200 GLDPR 204
Score = 45.2 bits (102), Expect = 0.002
Identities = 27/71 (38%), Positives = 39/71 (54%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L + K+V D L KDG +L+ID S+ PN +++ +KGL DAPVS
Sbjct: 68 TMLPNGKIVQDA-LFKDGAWQSLSADALVIDMSSSAPNDTRELAERLHQKGLRLVDAPVS 126
Query: 477 GGVMGAQNATL 509
GGV A +L
Sbjct: 127 GGVKRAVEGSL 137
Score = 41.5 bits (93), Expect = 0.023
Identities = 23/52 (44%), Positives = 29/52 (55%)
Frame = +1
Query: 100 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
S + VAF+GLG MGG MA +L+ F V G+D S +A A G PA
Sbjct: 2 SPRKNLRVAFIGLGAMGGPMAQHLLSAQFEVTGFDLSAEARERFAAVGGVPA 53
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 52.8 bits (121), Expect = 9e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V +V LG DGV+ + G++++D +T + ++I E G+GF DAPVSGG GA
Sbjct: 71 VREVVLGADGVLGALRPGAIIVDHTTTSAELAEEIAARTAEVGVGFVDAPVSGGEAGAMA 130
Query: 501 ATL 509
L
Sbjct: 131 GRL 133
Score = 48.8 bits (111), Expect = 2e-04
Identities = 24/65 (36%), Positives = 34/65 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+ M GG E ER+ P+L GA G +GSGQ+ K+ N +L+ AE +N I
Sbjct: 134 SIMCGGDPETIERARPVLAAYGATITRIGPVGSGQLTKMVNQILVAGAVEGAAEAINFAI 193
Query: 689 KMGLE 703
GL+
Sbjct: 194 AAGLD 198
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 52.8 bits (121), Expect = 9e-06
Identities = 28/66 (42%), Positives = 37/66 (56%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG + F + PLL MG K + CG G G AKLT N+++ MA E M + K
Sbjct: 136 FMIGGDEAVFSKIRPLLDPMGKKIYFCGGAGMGLQAKLTQNLVLSNILMAFNEGMVLATK 195
Query: 692 MGLEPK 709
G++PK
Sbjct: 196 GGMDPK 201
Score = 41.1 bits (92), Expect = 0.031
Identities = 20/61 (32%), Positives = 34/61 (55%)
Frame = +3
Query: 327 DVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNAT 506
+V LG G++ + G++++D STI ++I K + F DAPV+G GA++
Sbjct: 74 EVILGGQGLIQGLRAGAVVVDCSTIAVADSREIGAALKAKSVDFLDAPVTGSTPGAESGN 133
Query: 507 L 509
L
Sbjct: 134 L 134
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/63 (41%), Positives = 39/63 (61%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V + Y G+ G++ AK G++ D +T P + K+I+ A +K DAPVSGG +GA+N
Sbjct: 75 VEETYFGEKGLLKTAKPGTIFADMTTSSPILAKKIYDEAKKKECFSVDAPVSGGDIGAKN 134
Query: 501 ATL 509
TL
Sbjct: 135 GTL 137
Score = 33.5 bits (73), Expect = 6.2
Identities = 19/66 (28%), Positives = 28/66 (42%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+ MAGG + F+ P MG G G+GQ K+ N + + T E +
Sbjct: 138 SIMAGGDESAFKELEPFFACMGKTWALQGGAGAGQHTKMANQIAVAANLFGTVEAVCYAE 197
Query: 689 KMGLEP 706
GL+P
Sbjct: 198 AAGLDP 203
>UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
uncultured proteobacterium DelRiverFos06H03|Rep:
3-hydroxyisobutyrate dehydrogenase - uncultured
proteobacterium DelRiverFos06H03
Length = 299
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/70 (34%), Positives = 37/70 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+ GG K+ FE+ P+ V+G K FH G+ G+G KL N+L ++ A E + +G
Sbjct: 138 SIFVGGDKDCFEKHKPIFDVIGEKIFHVGEPGNGATIKLLTNLLWFVSAAAIGEGLMLGA 197
Query: 689 KMGLEPKFCW 718
K G+ W
Sbjct: 198 KAGIPLHTVW 207
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/55 (40%), Positives = 36/55 (65%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 485
V +V LG+ GV+AH K G+ +ID+ST + +++ +A KG+ F +APV+ V
Sbjct: 75 VREVMLGEQGVLAHVKAGATVIDTSTSAVELVQELVALAKSKGVDFLEAPVTNAV 129
Score = 38.7 bits (86), Expect = 0.16
Identities = 17/29 (58%), Positives = 22/29 (75%)
Frame = +1
Query: 127 FLGLGNMGGFMAANLVKKGFTVRGYDPSK 213
F+G+GNMG MAANLVK G+ V +D S+
Sbjct: 10 FIGVGNMGNPMAANLVKAGYPVTVFDVSR 38
>UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 315
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/70 (38%), Positives = 42/70 (60%)
Frame = +3
Query: 300 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 479
+L+S V D+ LG +GV+AH + L+ S+I + ++ A +G+G+ DAPVSG
Sbjct: 86 MLSSGPVCDDILLGPEGVIAHMAPHATLVVMSSIPVDTAQRQAQAAEARGIGYLDAPVSG 145
Query: 480 GVMGAQNATL 509
G GA + TL
Sbjct: 146 GERGAIDGTL 155
Score = 47.2 bits (107), Expect = 5e-04
Identities = 25/67 (37%), Positives = 35/67 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG FER PL +G + H G GSGQ+AKL N ++ T AE + +
Sbjct: 156 AIMVGGDPATFERHRPLFAPLG-RAVHVGPAGSGQLAKLANQSIVANTIATVAEALLLAE 214
Query: 689 KMGLEPK 709
+ G +P+
Sbjct: 215 RGGADPR 221
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 52.4 bits (120), Expect = 1e-05
Identities = 26/65 (40%), Positives = 37/65 (56%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
++ GG R+ P+L +MG K H G++GSG +AKL N LMGI AE + M +
Sbjct: 136 YLVGGDAHLVNRAEPVLSLMGKKVNHTGEMGSGALAKLVTNTLMGIQVTTIAELIGMLKR 195
Query: 692 MGLEP 706
G +P
Sbjct: 196 QGQDP 200
>UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 326
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/62 (40%), Positives = 41/62 (66%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L ++ V VYLG DG+VA+A+ G++L+D STI P++ ++ G+ F APV+
Sbjct: 71 TMLGTDDDVAQVYLGDDGLVANARAGAVLVDCSTISPDMSARVRARCDRAGVHFLAAPVA 130
Query: 477 GG 482
GG
Sbjct: 131 GG 132
>UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose
dehydrogenase:Prephenate dehydrogenase:NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Ralstonia eutropha JMP134|Rep:
UDP-glucose/GDP-mannose dehydrogenase:Prephenate
dehydrogenase:NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 294
Score = 52.0 bits (119), Expect = 2e-05
Identities = 29/95 (30%), Positives = 44/95 (46%)
Frame = +2
Query: 461 RCTCIWRSHGCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 640
R T +H + G + +ER PLL +G QF+ G ++ KL N+L
Sbjct: 114 RVTVSGNNHMAEAAKLTALVSGPADAYERIKPLLAALGPAQFYLGDAEQARLMKLVVNLL 173
Query: 641 MGITGMATAECMNMGIKMGLEPKFCWTC*TTHRLA 745
+ +TG AE + +G K GLE + W T +A
Sbjct: 174 IALTGGMLAEALTLGSKGGLEWQAMWDVITASAVA 208
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 52.0 bits (119), Expect = 2e-05
Identities = 24/66 (36%), Positives = 38/66 (57%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG D ER+ P+L+ +G + H G G+G K+ N +++G+T A AE M +
Sbjct: 127 AIMVGGTASDVERAEPILRALG-RPTHVGPPGAGHTVKVINQLIVGLTIQAVAEAMVLAE 185
Query: 689 KMGLEP 706
G++P
Sbjct: 186 AYGIDP 191
Score = 39.9 bits (89), Expect = 0.071
Identities = 19/48 (39%), Positives = 27/48 (56%)
Frame = +3
Query: 366 KKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
++G L+ID + DP + +G+G+ DAPVSGG GA TL
Sbjct: 79 REGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSGGPEGAAAGTL 126
Score = 35.1 bits (77), Expect = 2.0
Identities = 20/56 (35%), Positives = 29/56 (51%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQPLMEST 288
+A +GLG MG MA L+K GF V G+ ++ L+ A G+ A L + T
Sbjct: 3 IALIGLGLMGRPMARTLLKAGFNVTGW--NRSPLDPALTEGIPLAATLAEAAQAET 56
>UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 52.0 bits (119), Expect = 2e-05
Identities = 34/74 (45%), Positives = 45/74 (60%), Gaps = 3/74 (4%)
Frame = +3
Query: 297 SILTSNKVVLDVYLG-KDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLG-FTDA 467
SI+ K V VYL K GV+A K +G L+++ STID K++ E+GLG + DA
Sbjct: 27 SIVPGGKDVKTVYLDEKTGVIAARKDEGRLMLECSTIDVESTKEVGRKLKEEGLGTYIDA 86
Query: 468 PVSGGVMGAQNATL 509
PVSGGV A+ TL
Sbjct: 87 PVSGGVPAAEAGTL 100
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLP-LLKVMG--AKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMN 679
+ + G D LP L ++G +K F+ +G+G AK++NN L G +ATAE +
Sbjct: 101 SMLIGAPPPDPTSLLPSTLSLLGTPSKFFYLHTLGAGLTAKISNNYLSGTILLATAEALA 160
Query: 680 MGIKMGLEP 706
+G+K GL+P
Sbjct: 161 IGVKHGLDP 169
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/74 (36%), Positives = 38/74 (51%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G + + M GG + E + P L+ M AK H G G+G VAKL NNML+ + T
Sbjct: 134 GAASGQLSVMLGGETQWLEAARPALEAMAAKILHVGPSGAGNVAKLVNNMLVANHMVTTL 193
Query: 668 ECMNMGIKMGLEPK 709
E + +G G+ K
Sbjct: 194 EALRLGEAAGVAAK 207
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/45 (48%), Positives = 28/45 (62%)
Frame = +1
Query: 112 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 246
+K +GLG MG MA +L+K GF V GYDP++ A AA GV
Sbjct: 6 NKRAGVIGLGAMGLGMARSLLKAGFAVSGYDPAETARENAAAAGV 50
Score = 33.9 bits (74), Expect = 4.7
Identities = 18/54 (33%), Positives = 27/54 (50%)
Frame = +3
Query: 348 GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
G +A +++D+ST + + + G GF DAPVSGG GA + L
Sbjct: 87 GHLAQTGAARVIVDTSTSEAATSRTLAAELSALGHGFLDAPVSGGPAGAASGQL 140
>UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: Putative 2-hydroxyacid
dehydrogenase - alpha proteobacterium HTCC2255
Length = 303
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/67 (38%), Positives = 36/67 (53%)
Frame = +2
Query: 518 AGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 697
AGG KE ER P++++MG + G GSG + KL +N L I A E + M +K G
Sbjct: 136 AGGDKETIERIRPVMELMGPVHY-MGSNGSGSITKLASNQLWAIHATAMGEALVMAVKSG 194
Query: 698 LEPKFCW 718
+E W
Sbjct: 195 VELSRAW 201
>UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=24;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 298
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/64 (39%), Positives = 33/64 (51%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
AFM G DF L M H G G+GQ AK+ NNML+G++ + T E +
Sbjct: 132 AFMVGCEASDFAAVEAALAPMSRVTIHAGDHGAGQAAKICNNMLLGVSMLGTCEAFALAE 191
Query: 689 KMGL 700
K+GL
Sbjct: 192 KLGL 195
Score = 50.8 bits (116), Expect = 4e-05
Identities = 25/53 (47%), Positives = 34/53 (64%)
Frame = +3
Query: 351 VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
++ +A K +LLID STID + + + A E G F DAPVSGG+M A+ TL
Sbjct: 79 ILPNAPKSALLIDCSTIDVDSARVVARQAAEAGFRFADAPVSGGIMAAEAGTL 131
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/55 (41%), Positives = 31/55 (56%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQPLMES 285
+AF+GLGNMGG MAAN K VR +D S A+ A G A + + + E+
Sbjct: 4 IAFIGLGNMGGGMAANQAKAQHQVRAFDLSAAAVERAVAAGCLAAASVAEAVAEA 58
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/72 (34%), Positives = 35/72 (48%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G E A MAGG D ER P + M + H G G+GQ AKL N +++G A
Sbjct: 150 GAEEGTLAIMAGGDASDIERVRPYVLTMARRFTHMGPTGAGQTAKLCNQVIVGCAMAVLA 209
Query: 668 ECMNMGIKMGLE 703
E + + G++
Sbjct: 210 EATRLAVNAGID 221
Score = 46.4 bits (105), Expect = 8e-04
Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVSG 479
+T V +V G +G+ G L++D S+I P+ + + + G G+ DAPVSG
Sbjct: 87 VTDAAAVEEVIFGAEGLSTAPGAGKLVVDFSSIHPDAARDLATRLKAANGAGWIDAPVSG 146
Query: 480 GVMGAQNATL 509
G GA+ TL
Sbjct: 147 GTKGAEEGTL 156
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 51.2 bits (117), Expect = 3e-05
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V V G++GV+A K+G+ ID +++ P + ++I GL DAPVSGG GA+N
Sbjct: 80 VASVLFGENGVLAAMKRGATFIDHTSVSPGLARRIADECERLGLHAVDAPVSGGQAGAEN 139
Query: 501 ATL 509
L
Sbjct: 140 GKL 142
Score = 35.1 bits (77), Expect = 2.0
Identities = 16/30 (53%), Positives = 20/30 (66%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD 204
K +AFLGLG MGG M +LV+ G GY+
Sbjct: 5 KRIAFLGLGVMGGPMWGHLVRAGHEATGYN 34
Score = 34.7 bits (76), Expect = 2.7
Identities = 14/43 (32%), Positives = 24/43 (55%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 637
+ M GG +E + P+++ A+ H G+ G+GQ AK N +
Sbjct: 143 SIMCGGSEEAMASAQPVMQAYAARIVHIGEAGAGQTAKAINQV 185
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/66 (42%), Positives = 36/66 (54%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L + V +V G GV + GSL+ID STI P+ I EK + F DAPVS
Sbjct: 62 TMLPDSPEVEEVLFGPAGVTTTLRPGSLVIDCSTISPDAAVAIGARLAEKDIAFVDAPVS 121
Query: 477 GGVMGA 494
GG GA
Sbjct: 122 GGEAGA 127
Score = 37.5 bits (83), Expect = 0.38
Identities = 18/65 (27%), Positives = 32/65 (49%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG ++ R+ +L + A H G +G+GQ+ K N ML+ E + +
Sbjct: 133 AVMMGGDEDAVRRAATVLDAVAATSVHVGPVGAGQLVKAANQMLVAGNIALVGEAVTLLQ 192
Query: 689 KMGLE 703
+ G++
Sbjct: 193 RTGVD 197
>UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus
Pelagibacter ubique|Rep: MmsB-like protein - Candidatus
Pelagibacter ubique HTCC1002
Length = 308
Score = 50.8 bits (116), Expect = 4e-05
Identities = 27/67 (40%), Positives = 39/67 (58%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S+L K V +YLG G++ K L+ID STID ++ + + G+ DAPV+
Sbjct: 64 SMLPEGKHVRSLYLGDKGILNKIPKECLIIDCSTIDIETSLELGNESKKLGIKMIDAPVT 123
Query: 477 GGVMGAQ 497
GGVMGA+
Sbjct: 124 GGVMGAR 130
Score = 48.0 bits (109), Expect = 3e-04
Identities = 23/66 (34%), Positives = 37/66 (56%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
F+ GG E + PL +MG K H G GSG K+ NNM +GI+ +A +E + + +
Sbjct: 136 FLVGGSDEAVALAKPLFDIMGQKILHAGVQGSGVGVKICNNMSLGISMIAASESLMLAKR 195
Query: 692 MGLEPK 709
+ ++ K
Sbjct: 196 LKMDIK 201
Score = 41.9 bits (94), Expect = 0.018
Identities = 18/43 (41%), Positives = 29/43 (67%)
Frame = +1
Query: 118 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 246
++AF+G+GNMG MA LVK G V+ +D S + + A ++G+
Sbjct: 4 HIAFIGVGNMGNPMADQLVKAGKEVKAFDVSPEVIKIAKESGL 46
>UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 50.8 bits (116), Expect = 4e-05
Identities = 23/65 (35%), Positives = 39/65 (60%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A +AGG +R PLL ++ A+ G +G+GQ AKL N +++ +A AE M++G
Sbjct: 136 AILAGGDAAAIDRVRPLLALLSARVTRMGGVGAGQAAKLCNQLIVATNMLAIAEAMHVGE 195
Query: 689 KMGLE 703
+G++
Sbjct: 196 ALGID 200
Score = 43.2 bits (97), Expect = 0.008
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTDAPVSG 479
LT V V G+ G G+L++D STI P+ + E G + D PVSG
Sbjct: 66 LTDADAVEQVMFGEGGAARALAPGALVVDFSTIGPDATRGFAKRLAETGDAQWLDCPVSG 125
Query: 480 GVMGAQNATL 509
GV GA+ TL
Sbjct: 126 GVAGAEAGTL 135
>UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with
NAD(P)-binding Rossmann-fold domain; n=2; Bacteria|Rep:
Predicted dehydrogenase, with NAD(P)-binding
Rossmann-fold domain - Rhodobacterales bacterium
HTCC2150
Length = 302
Score = 50.4 bits (115), Expect = 5e-05
Identities = 26/63 (41%), Positives = 35/63 (55%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V V G+ G++AH KG +I S+TI P ++I + G+ D PVSGG GAQ
Sbjct: 70 VKSVLFGEGGLLAHMPKGGAVILSATIKPVEAEEIGAAMADSGIHLIDTPVSGGFPGAQG 129
Query: 501 ATL 509
TL
Sbjct: 130 GTL 132
Score = 33.5 bits (73), Expect = 6.2
Identities = 15/38 (39%), Positives = 22/38 (57%)
Frame = +1
Query: 130 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
+GLG+MG +A NL+K GF G D + + A + G
Sbjct: 6 IGLGDMGSGLAKNLLKAGFETTGIDMKPERMAAFVEMG 43
>UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep:
Bll1384 protein - Bradyrhizobium japonicum
Length = 356
Score = 50.0 bits (114), Expect = 7e-05
Identities = 27/66 (40%), Positives = 36/66 (54%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M G K +FE P L V+G F + G+ Q KL NN L +AT+E + MG+
Sbjct: 186 AVMVSGPKAEFELLKPALDVIGKVFFIGEKPGAAQTMKLANNFLSATAIVATSEAVVMGV 245
Query: 689 KMGLEP 706
K GL+P
Sbjct: 246 KAGLDP 251
Score = 42.7 bits (96), Expect = 0.010
Identities = 19/61 (31%), Positives = 34/61 (55%)
Frame = +1
Query: 76 YTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
++ +R ++ ++ F+GLGNMG MA L++ G + +D K+ ++ G TPA
Sbjct: 42 FSRQQRIINTRNTMDIGFIGLGNMGFPMARRLIEAGNRLVVFDTRKEVVDKLVARGATPA 101
Query: 256 T 258
T
Sbjct: 102 T 102
Score = 39.1 bits (87), Expect = 0.12
Identities = 23/69 (33%), Positives = 36/69 (52%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L S + L+V G +GV+ + ID ST+ + +I + ++ + D PVSGG
Sbjct: 118 LPSLQASLEVATGTNGVI-EGSRVKRFIDLSTVGSTMASKIHGLLAKRDIVQIDCPVSGG 176
Query: 483 VMGAQNATL 509
V GA+ TL
Sbjct: 177 VGGAEKGTL 185
>UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulosus
HTCC2516|Rep: Oxidoreductase - Oceanicola granulosus
HTCC2516
Length = 288
Score = 50.0 bits (114), Expect = 7e-05
Identities = 20/64 (31%), Positives = 37/64 (57%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ GG++ D ER+ ++ + A H G +G+GQ AK N ++G+ + AE + + K
Sbjct: 131 LLGGQERDIERARAVIDALAANATHLGPLGAGQAAKTLNQAIVGVNYVLMAELLALARKS 190
Query: 695 GLEP 706
G++P
Sbjct: 191 GIDP 194
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 50.0 bits (114), Expect = 7e-05
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 360 HAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
+ KKGS+++D+ST +P+ K++ A G F D PVSGG +GA+ T+
Sbjct: 93 YLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSGGPLGARTGTM 142
Score = 39.5 bits (88), Expect = 0.094
Identities = 19/62 (30%), Positives = 30/62 (48%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ GG + F + PLL+ M K H G G+G K+ NN+L + +E M +
Sbjct: 145 VVGGDEAGFTKVRPLLEKMTGKLVHIGPSGAGHTVKIANNLLCAANLVLMSEMAQMAERA 204
Query: 695 GL 700
G+
Sbjct: 205 GI 206
>UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 293
Score = 50.0 bits (114), Expect = 7e-05
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVSG 479
+T K + V G DG+V + ++++D ST+ P+ +QI + E G + DAPVSG
Sbjct: 64 VTDAKALDAVLFGSDGIVGAGRVPAMIVDHSTVPPDATRQIAARVRAEAGAAWVDAPVSG 123
Query: 480 GVMGA 494
G+ GA
Sbjct: 124 GLAGA 128
Score = 46.0 bits (104), Expect = 0.001
Identities = 22/67 (32%), Positives = 34/67 (50%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A GG D R+ P+L +G H G GSGQVAK N ++ ++ A AE + +
Sbjct: 134 AIFVGGEDADVTRAWPVLTTLGTTVTHLGPTGSGQVAKACNQVIGFLSFAALAEALALAA 193
Query: 689 KMGLEPK 709
+ + P+
Sbjct: 194 RYDIAPR 200
>UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 355
Score = 50.0 bits (114), Expect = 7e-05
Identities = 25/65 (38%), Positives = 36/65 (55%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A MAGG D E PLL ++ H G +G+GQ AKL N ++ T A AE +++
Sbjct: 195 AVMAGGAAADVEAVKPLLGAYASRVTHMGDVGAGQTAKLCNQTIVTATLAAIAEAVSLAQ 254
Query: 689 KMGLE 703
+ GL+
Sbjct: 255 RSGLD 259
>UniRef50_Q9V8M5-2 Cluster: Isoform C of Q9V8M5 ; n=1; Drosophila
melanogaster|Rep: Isoform C of Q9V8M5 - Drosophila
melanogaster (Fruit fly)
Length = 227
Score = 49.6 bits (113), Expect = 9e-05
Identities = 24/57 (42%), Positives = 32/57 (56%)
Frame = +1
Query: 79 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 249
T R + KN+ F+GLGNMG MA+NL+K G + +D SK A + A G T
Sbjct: 17 TLVRAMSTQGGAKNIGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGAT 73
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 49.6 bits (113), Expect = 9e-05
Identities = 22/63 (34%), Positives = 39/63 (61%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V ++ GK G++ G+++ID +T + K++ +AL+K + F DAP+SGG GA++
Sbjct: 91 VREMMSGKKGILNSVNPGTIIIDHTTTSATLSKEMNELALQKDVIFLDAPISGGQAGAES 150
Query: 501 ATL 509
L
Sbjct: 151 GQL 153
Score = 37.5 bits (83), Expect = 0.38
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG K +E P+L + G GSGQ+ K+ N + + A AE +N K+
Sbjct: 156 MVGGDKASYESVKPILDNYSKFTKYMGPSGSGQLTKMVNQICIAGLVQALAEGVNFSEKV 215
Query: 695 GL 700
GL
Sbjct: 216 GL 217
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 49.6 bits (113), Expect = 9e-05
Identities = 22/67 (32%), Positives = 33/67 (49%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A + GG + R PLL MG H G G+G AK NN + + AT E + +
Sbjct: 139 AILVGGHADVLARCKPLLDAMGTNVLHIGTAGAGHAAKALNNYVSAASVAATVEALQIAS 198
Query: 689 KMGLEPK 709
+ G++P+
Sbjct: 199 RFGIDPQ 205
Score = 42.7 bits (96), Expect = 0.010
Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 3/99 (3%)
Frame = +3
Query: 222 ERSGQERSDASNSIXXXXXXXXXXXSILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDS 392
E+SG R +A N+ ++L ++ +V V LG G A KG+++ID
Sbjct: 45 EQSGSHRLNADNA-----GSLDALITMLPNSAIVEAVVLGDGNNTGWAARLAKGAVVIDM 99
Query: 393 STIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
S+ +P + + + L + DAPVSGGV A+ TL
Sbjct: 100 SSSEPERSRALGKTLEAQRLAYLDAPVSGGVKRAKEGTL 138
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 49.6 bits (113), Expect = 9e-05
Identities = 27/68 (39%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Frame = +3
Query: 309 SNKVVLDVYLGKDGVVA-HAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 485
+N + L +DG +A HA+ GS+++D STID I +G+ + D PVSGG
Sbjct: 73 TNTADVQSLLFRDGGIAQHAQPGSIIVDFSTIDAAAVADIARQLKSRGVDYIDCPVSGGA 132
Query: 486 MGAQNATL 509
GA+ ATL
Sbjct: 133 AGARAATL 140
Score = 47.2 bits (107), Expect = 5e-04
Identities = 25/65 (38%), Positives = 33/65 (50%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+ MAGG F R P+LK +G H G G+GQ K N M + I + AE MN +
Sbjct: 141 SMMAGGDLAAFNRIEPMLKHLGKTIRHVGPSGAGQAIKAANQMALCIQLVGIAEAMNYAL 200
Query: 689 KMGLE 703
+ G E
Sbjct: 201 EQGAE 205
Score = 40.3 bits (90), Expect = 0.054
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +1
Query: 109 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQPLMEST 288
T + F+GLGNMG MA +L K G+TV + + A A + P P ++ L ST
Sbjct: 7 TLNTIGFIGLGNMGAAMAGHLCKAGYTVLAWARNASTFEALADIPLVP-QPSIEALCAST 65
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 49.6 bits (113), Expect = 9e-05
Identities = 34/113 (30%), Positives = 52/113 (46%), Gaps = 3/113 (2%)
Frame = +3
Query: 180 GFHSSRLRSFQRCTERSGQERSDASNSIXXXXXXXXXXXSILTSNKVVLDVYLG---KDG 350
GF + R +RS + + + ++L + ++ V LG + G
Sbjct: 24 GFDVVGFDADSRTNQRSAETGIPVAADVVDAVTGADVVITMLPNGDILRQVLLGAGAESG 83
Query: 351 VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
V+ + G+L+IDSS+ID + A G+ F DAPVSGGV GA TL
Sbjct: 84 VLNYLAPGALVIDSSSIDVANCLAVHESAASAGIAFLDAPVSGGVGGAAAGTL 136
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/66 (34%), Positives = 35/66 (53%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM GG + R+ PL + MG K G +GQ K+ N M+ + +A AE ++ K
Sbjct: 138 FMVGGDEAHVRRAWPLFEAMGKKVVRVGGPSTGQAVKMCNQMIYASSLVAVAEAFSLADK 197
Query: 692 MGLEPK 709
+G+ PK
Sbjct: 198 LGVAPK 203
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/51 (39%), Positives = 30/51 (58%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLL 267
+ +AF+GLGNMG MA NL+ GF V G+D +A+ G+ A ++
Sbjct: 2 ERIAFIGLGNMGNSMAKNLIAAGFDVVGFDADSRTNQRSAETGIPVAADVV 52
>UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: BtdhL
- Azoarcus anaerobius
Length = 303
Score = 49.6 bits (113), Expect = 9e-05
Identities = 22/63 (34%), Positives = 37/63 (58%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+A G K+ +ER LPLL+ MG K ++ G + K+ NM++G+T E + +G +
Sbjct: 141 LASGPKDAYERCLPLLQAMGKKLYYLGPAEQARYLKVAINMMLGVTAGMLGEALALGERG 200
Query: 695 GLE 703
G+E
Sbjct: 201 GVE 203
Score = 39.5 bits (88), Expect = 0.094
Identities = 22/71 (30%), Positives = 35/71 (49%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S+++ + + + L GV A G + ID ST+ P + ++I A KG+ + APVS
Sbjct: 68 SMVSDDAALQGITLDAGGVFEAATPGMVFIDMSTVSPALSERIAAAASAKGIHYLRAPVS 127
Query: 477 GGVMGAQNATL 509
G A L
Sbjct: 128 GSTTTAAAGAL 138
Score = 34.7 bits (76), Expect = 2.7
Identities = 18/48 (37%), Positives = 25/48 (52%)
Frame = +1
Query: 112 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
D V ++GLG MG MAANL+ G + Y+ S +A + G A
Sbjct: 6 DTRVGWIGLGKMGTPMAANLLAAGHAITVYNRSAARADALVEKGAALA 53
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 49.6 bits (113), Expect = 9e-05
Identities = 25/62 (40%), Positives = 36/62 (58%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+A G K FE S+P V+G + F+ GQ+G+G KL NM+MG A +E + + K
Sbjct: 135 LAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKS 194
Query: 695 GL 700
GL
Sbjct: 195 GL 196
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/71 (30%), Positives = 32/71 (45%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L+ L V K GV+ +G ID ST+D +I KG F + PVS
Sbjct: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
Query: 477 GGVMGAQNATL 509
G A++ L
Sbjct: 122 GSKKPAEDGQL 132
Score = 33.1 bits (72), Expect = 8.2
Identities = 16/43 (37%), Positives = 25/43 (58%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 249
V FLGLG MG M+ NL+K GF V ++ + + ++G +
Sbjct: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGAS 45
>UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Frankia alni ACN14a|Rep: 3-hydroxyisobutyrate
dehydrogenase - Frankia alni (strain ACN14a)
Length = 313
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/63 (39%), Positives = 34/63 (53%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V V LG DG + G+ ++D +T + +I A E G+GF DAPVSGG GA+
Sbjct: 71 VRSVLLGPDGALGALAPGATIVDHTTTSAELAVEIAARAAEVGVGFVDAPVSGGQAGAEA 130
Query: 501 ATL 509
L
Sbjct: 131 GRL 133
Score = 42.7 bits (96), Expect = 0.010
Identities = 21/63 (33%), Positives = 31/63 (49%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG + ER P+L GA G +G+GQ+ K+ N +L+ AE +N
Sbjct: 136 MCGGEVDTVERVRPVLAAYGATITRIGPVGTGQLTKMVNQILVAGAIEGAAEALNFAAAA 195
Query: 695 GLE 703
GL+
Sbjct: 196 GLD 198
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/53 (43%), Positives = 33/53 (62%)
Frame = +3
Query: 351 VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
V+ +G +++D STIDP+ +++ A G F DAPVSGGV GA+ TL
Sbjct: 79 VLQQGNQGLVIVDHSTIDPDTTRRLAQDAQVAGACFLDAPVSGGVQGAEAGTL 131
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/65 (30%), Positives = 33/65 (50%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG + ++ +PL++ FH G GSGQ KL NN + +A E ++ +
Sbjct: 132 AVMLGGDEASVKKVIPLIETYAGNIFHVGPSGSGQAIKLANNQITAANIVALGEGLSSAV 191
Query: 689 KMGLE 703
G++
Sbjct: 192 AAGVD 196
Score = 39.9 bits (89), Expect = 0.071
Identities = 20/41 (48%), Positives = 27/41 (65%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
V F+GLGN+GG + A+LVK G V YD + A++AA G
Sbjct: 5 VGFVGLGNIGGRVVAHLVKAGHDVAVYDLNTAAVDAAVALG 45
>UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase - Sphingomonas
wittichii RW1
Length = 264
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/69 (33%), Positives = 41/69 (59%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
+ S++ V DV G+DGV+A A+ G +++ S++ + + ++G+ DAPVSGG
Sbjct: 64 VVSDQQVRDVLAGEDGVLASARPGLIVVLHSSVSTDTIAEAAKATRDRGVVLVDAPVSGG 123
Query: 483 VMGAQNATL 509
GA+ T+
Sbjct: 124 AQGARARTM 132
Score = 40.3 bits (90), Expect = 0.054
Identities = 22/73 (30%), Positives = 35/73 (47%)
Frame = +2
Query: 482 SHGCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 661
+ G R +FM GG + +R PL ++ G G G+ +AKL + + + MA
Sbjct: 124 AQGARARTMSFMVGGEEAALDRCQPLFELSGPNILRTGPAGTATLAKLAHQVAIIGNIMA 183
Query: 662 TAECMNMGIKMGL 700
AE + +G GL
Sbjct: 184 MAEAVRLGTAGGL 196
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/54 (42%), Positives = 34/54 (62%)
Frame = +3
Query: 348 GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
G ++ + G +L+D +T DP++ +I A +G DAPVSGG GA+NATL
Sbjct: 128 GALSGLRPGGVLVDMTTSDPSLAAEIASSAASRGCFSVDAPVSGGDRGAKNATL 181
Score = 36.3 bits (80), Expect = 0.88
Identities = 23/65 (35%), Positives = 31/65 (47%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A AGG + R PL +G K + G G GQ AKL N +++ T + E M
Sbjct: 182 AIFAGGDESVVRRLNPLFSHLG-KVNYMGGPGKGQYAKLANQIIIASTMLGLIEGMMYAY 240
Query: 689 KMGLE 703
K GL+
Sbjct: 241 KSGLD 245
>UniRef50_Q0C8I2 Cluster: Predicted protein; n=3;
Pezizomycotina|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 320
Score = 48.8 bits (111), Expect = 2e-04
Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 4/71 (5%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLL----KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECM 676
AF G K D +LPLL ++MG + CG G AKL NN L G+ +A +E +
Sbjct: 148 AFFLGCAKTD--PNLPLLTDTLRLMGKEVIPCGGPSLGLSAKLCNNYLSGLIAIANSEAL 205
Query: 677 NMGIKMGLEPK 709
N+G++ GL+P+
Sbjct: 206 NIGMRAGLDPR 216
Score = 37.1 bits (82), Expect = 0.50
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +3
Query: 330 VYLGKD-GVVAHAKKGSLLIDSSTIDP--NVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
VYL + GV + LLID STID ++ + F DAPVSGGV+GAQ
Sbjct: 85 VYLDESTGVCSTPLDTRLLIDCSTIDTATSLAVKAHITTHHASASFYDAPVSGGVLGAQK 144
Query: 501 ATLPSWPEVVKKTSKGPFLS 560
+ + K P L+
Sbjct: 145 GAIAFFLGCAKTDPNLPLLT 164
>UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 315
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/71 (32%), Positives = 36/71 (50%)
Frame = +2
Query: 494 SERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAEC 673
S R +AGG + D +R P+ ++ G + G +GS Q+ KL NN L + A E
Sbjct: 141 SGRQLVVLAGGDRRDVDRCAPVFELFGRTVVYTGDVGSAQLTKLVNNALFIVHRSAAIEA 200
Query: 674 MNMGIKMGLEP 706
+ +GL+P
Sbjct: 201 LRAAGTLGLDP 211
Score = 33.5 bits (73), Expect = 6.2
Identities = 19/58 (32%), Positives = 29/58 (50%)
Frame = +3
Query: 309 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
S++ V V G G++ + GSL++ ST P + A +G+ DAPVS G
Sbjct: 79 SDEDVRTVVAGPGGLLETMRSGSLVVIHSTCSPRTCVDLAARARGRGITVLDAPVSNG 136
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/68 (38%), Positives = 36/68 (52%)
Frame = +2
Query: 497 ERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECM 676
+R + GG +E +ER+ ++K H G G G AKL NN L+G A AE +
Sbjct: 131 KREAVVLIGGEREAYERAYEVVKHFARYVVHVGPNGYGLYAKLINNALLGSYVAALAEVV 190
Query: 677 NMGIKMGL 700
N+G MGL
Sbjct: 191 NLGEAMGL 198
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/61 (37%), Positives = 37/61 (60%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
SI++ + V + LG++GV+ K+GSL+I+ STI P+ ++ EKG DAP+
Sbjct: 64 SIVSDDDAVKSIMLGENGVINGIKQGSLVIEMSTISPSTSIELANKIKEKGGLMVDAPII 123
Query: 477 G 479
G
Sbjct: 124 G 124
>UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Janthinobacterium sp. Marseille|Rep:
3-hydroxyisobutyrate dehydrogenase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 298
Score = 48.0 bits (109), Expect = 3e-04
Identities = 25/65 (38%), Positives = 30/65 (46%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M G ER PL MG K + CG IGS V K N + + T E M +G K
Sbjct: 139 MVSGDDASIERCRPLFDAMGRKLWPCGDIGSAHVLKAMTNYINACALINTLEAMTIGRKF 198
Query: 695 GLEPK 709
GL+ K
Sbjct: 199 GLDSK 203
Score = 47.6 bits (108), Expect = 4e-04
Identities = 28/70 (40%), Positives = 40/70 (57%)
Frame = +3
Query: 300 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 479
+L S++VV V L DG+ GS+ ID T P V + I G+G+ DAPV G
Sbjct: 68 MLPSDQVVRQV-LFTDGLATQLAPGSIAIDMGTSAPAVTRSISAELATLGIGYLDAPVMG 126
Query: 480 GVMGAQNATL 509
GV+ A++A+L
Sbjct: 127 GVVFAKDASL 136
Score = 43.2 bits (97), Expect = 0.008
Identities = 18/41 (43%), Positives = 26/41 (63%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK 237
+N+ F+G+GNMG MA L +KGF++ YD NA A+
Sbjct: 5 RNIGFIGIGNMGAPMAGQLARKGFSLTVYDTHATTANAFAQ 45
>UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Roseiflexus|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Roseiflexus sp. RS-1
Length = 302
Score = 48.0 bits (109), Expect = 3e-04
Identities = 25/62 (40%), Positives = 33/62 (53%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ GGR D ER+ P L V+G + H G G+G KL NM M A AE + +G +
Sbjct: 136 LVGGRTSDLERARPALGVLGRRIIHLGGQGAGTTMKLVLNMTMACFWGALAESLAVGQQF 195
Query: 695 GL 700
GL
Sbjct: 196 GL 197
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/71 (35%), Positives = 38/71 (53%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
+ILT + V VY G+DG+++ G L I+ STI + + + ++G DAPVS
Sbjct: 63 TILTDDHAVETVYCGRDGLLSTDASGRLFIEMSTIRTSTILSLAGMVDQRGARLLDAPVS 122
Query: 477 GGVMGAQNATL 509
G V A+ L
Sbjct: 123 GTVAPAREGQL 133
>UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidiphilium cryptum (strain JF-5)
Length = 305
Score = 48.0 bits (109), Expect = 3e-04
Identities = 23/66 (34%), Positives = 36/66 (54%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+ M GG +D R+ LL++MG H G IG+GQ K NN++ + E + +G
Sbjct: 133 SIMTGGSADDCARAETLLRLMGTTITHVGDIGAGQAMKALNNLVSAGGFLIGVEALLIGQ 192
Query: 689 KMGLEP 706
+ GL+P
Sbjct: 193 RFGLDP 198
Score = 36.3 bits (80), Expect = 0.88
Identities = 20/41 (48%), Positives = 24/41 (58%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK 237
+ VAF+GLGNMG MAA LV G V G D + A A+
Sbjct: 3 QRVAFIGLGNMGWPMAARLVGGGCEVTGCDAVEGRAEAFAR 43
>UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovarius
nubinhibens ISM|Rep: Probable oxidoreductase -
Roseovarius nubinhibens ISM
Length = 320
Score = 48.0 bits (109), Expect = 3e-04
Identities = 24/63 (38%), Positives = 35/63 (55%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
MAGGR EDF + P+ + K H G GSG K+ NN + ++ + TAE + M K
Sbjct: 146 MAGGRAEDFADAAPVFAPLADKIVHLGPKGSGIRMKIANNYMSMVSMVLTAETLAMARKA 205
Query: 695 GLE 703
G++
Sbjct: 206 GID 208
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/71 (36%), Positives = 33/71 (46%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
+IL + V + LG G+ A G+L+I+ STI P I KGL DAPV
Sbjct: 73 TILPRDTHVRQICLGAGGIADSAAPGTLVIEMSTISPEASLDIHDALTSKGLRVLDAPVG 132
Query: 477 GGVMGAQNATL 509
AQN L
Sbjct: 133 RTPKDAQNGAL 143
Score = 41.9 bits (94), Expect = 0.018
Identities = 23/52 (44%), Positives = 28/52 (53%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQ 270
+ VAF+GLG MG MAA LV G VRG D L A + G PA + +
Sbjct: 12 RRVAFIGLGTMGSGMAARLVAAGHEVRGVDIDSARLAAFEEVGGLPAASVAE 63
>UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and
related beta-hydroxyacid dehydrogenases; n=2;
Prochlorococcus marinus|Rep: 3-hydroxyisobutyrate
dehydrogenase and related beta-hydroxyacid
dehydrogenases - Prochlorococcus marinus (strain NATL1A)
Length = 287
Score = 48.0 bits (109), Expect = 3e-04
Identities = 26/69 (37%), Positives = 35/69 (50%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
+T + V V G +GV K S +ID STI P+ I E+ + + D PVSGG
Sbjct: 60 VTDDNAVESVLFGDNGVSGSLKPNSFVIDFSTISPDKSISIHKRLGEQNIFYVDCPVSGG 119
Query: 483 VMGAQNATL 509
GA N +L
Sbjct: 120 TEGAHNGSL 128
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 47.6 bits (108), Expect = 4e-04
Identities = 22/65 (33%), Positives = 32/65 (49%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GGR E E+ P+L MG++ H G G+GQ K N ++ A E + G
Sbjct: 131 ALMIGGRAETVEKVRPVLAAMGSRLMHMGDTGAGQATKAVNQVMCAGINQAVTEALAFGQ 190
Query: 689 KMGLE 703
+ L+
Sbjct: 191 ALDLD 195
Score = 41.1 bits (92), Expect = 0.031
Identities = 18/48 (37%), Positives = 30/48 (62%)
Frame = +3
Query: 366 KKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
+ G++++D ST+ ++ + + G F DAPVSGGV GA++ TL
Sbjct: 83 RPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDAPVSGGVEGARDGTL 130
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 47.6 bits (108), Expect = 4e-04
Identities = 23/65 (35%), Positives = 34/65 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+ MAGG F ++ P + MG H G G+GQVAK N ++ G+ +A AE
Sbjct: 130 SIMAGGSDAAFAKAKPAFECMGKNIVHVGASGAGQVAKAANQIVTGMGVLAVAEAFAFAA 189
Query: 689 KMGLE 703
K G++
Sbjct: 190 KNGVD 194
Score = 40.7 bits (91), Expect = 0.041
Identities = 20/49 (40%), Positives = 28/49 (57%)
Frame = +3
Query: 348 GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 494
GV + + G + +D STI P ++I G+ F DAPVSGG +GA
Sbjct: 76 GVASAGESGLVAVDMSTIAPAAARRIGEDLAAAGIDFIDAPVSGGEVGA 124
Score = 33.9 bits (74), Expect = 4.7
Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 4/49 (8%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTV----RGYDPSKDALNAAAKNGVTPA 255
+ F+GLG MG MA NL+K G V R + + L+A AK +PA
Sbjct: 3 IGFIGLGIMGRPMALNLIKGGHQVTVWARRAESMQPLLDAGAKGAASPA 51
>UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein precursor; n=7; Bacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein
precursor - Mycobacterium sp. (strain MCS)
Length = 299
Score = 47.6 bits (108), Expect = 4e-04
Identities = 21/49 (42%), Positives = 31/49 (63%)
Frame = +1
Query: 109 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
++ ++ F+GLGNMG MAANL+ G V Y+ S D ++A + G PA
Sbjct: 2 SNMHIGFIGLGNMGSAMAANLLAAGHDVTAYNRSPDKVDALSAEGARPA 50
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/71 (30%), Positives = 35/71 (49%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L ++ V V G DG+VA + ++ + SSTI + +++ E G F APV
Sbjct: 64 TMLANDDAVEAVSFGDDGIVASLRPDAIHVSSSTISLALAERLTAAHAEGGSRFVSAPVF 123
Query: 477 GGVMGAQNATL 509
G A A L
Sbjct: 124 GRPEAAAAAKL 134
>UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_1503;
n=167; Bacteria|Rep: Uncharacterized oxidoreductase
Sfri_1503 - Shewanella frigidimarina (strain NCIMB 400)
Length = 291
Score = 47.6 bits (108), Expect = 4e-04
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 330 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
V LG+ G+V G++L+D +T +V ++I + F DAPVSGG GA+N L
Sbjct: 75 VVLGEHGIVHGMHAGAILVDHTTASADVAREIAAYIEPLNIAFLDAPVSGGQAGAENGAL 134
>UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycoplasma penetrans|Rep: 3-hydroxyisobutyrate
dehydrogenase - Mycoplasma penetrans
Length = 288
Score = 47.2 bits (107), Expect = 5e-04
Identities = 23/57 (40%), Positives = 34/57 (59%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMN 679
+ M GG E F++ +LK++G K + G G GQ AKL N +L+ + ATAE +N
Sbjct: 132 SIMVGGDFETFKKVESILKILGNKINYFGSAGKGQHAKLFNQILVAVNTFATAEVLN 188
Score = 43.6 bits (98), Expect = 0.006
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Frame = +3
Query: 321 VLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQ 497
VLD+YL + G+ + + ID +T PN Q+ + KG+ DAPV+GG +GA
Sbjct: 70 VLDIYLNDEYGIFNYVSSEQICIDFTTSSPNFAVQLANNS--KGIKVLDAPVTGGDIGAL 127
Query: 498 NATL 509
N TL
Sbjct: 128 NGTL 131
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 47.2 bits (107), Expect = 5e-04
Identities = 23/65 (35%), Positives = 34/65 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A MAGGR D + PL+ ++ H G G+GQ AKL N ++ T A AE + +
Sbjct: 126 AVMAGGRAADLDAVRPLIDTYASRITHMGDAGAGQTAKLCNQAIVTATVTAIAEAVGLAQ 185
Query: 689 KMGLE 703
G++
Sbjct: 186 ASGID 190
Score = 46.8 bits (106), Expect = 6e-04
Identities = 27/68 (39%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Frame = +3
Query: 315 KVVLDVYLGKDGVV---AHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 485
+ V DV G+ G++ A A++ ++D S+I P + A G+G+ DAPVSGGV
Sbjct: 58 RAVGDVVFGEHGLLSGDAAARRLQRIVDHSSIPPAATRDYAARATALGVGWVDAPVSGGV 117
Query: 486 MGAQNATL 509
GAQ TL
Sbjct: 118 PGAQAGTL 125
>UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase
protein; n=2; Burkholderiales|Rep: Putative
dehydrogenase/oxidoreductase protein - Burkholderia
xenovorans (strain LB400)
Length = 300
Score = 47.2 bits (107), Expect = 5e-04
Identities = 23/69 (33%), Positives = 34/69 (49%)
Frame = +2
Query: 500 RYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMN 679
R F GG +E+ PLL+ + +F G G+ KL N L+ + +A AE MN
Sbjct: 136 RKACFYVGGTDSVYEKCEPLLQAITDNRFFLGAFGTAVSMKLIANYLVTVNTLAAAEAMN 195
Query: 680 MGIKMGLEP 706
+G + G P
Sbjct: 196 LGTRAGFSP 204
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 47.2 bits (107), Expect = 5e-04
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+AGG + PLL MG K +CG GSG KL N+L+GI AE +++
Sbjct: 137 LAGGPEAAVRAQEPLLLSMGKKVIYCGPTGSGSAMKLAINLLLGIMTEGIAEALHLAESS 196
Query: 695 GL 700
GL
Sbjct: 197 GL 198
Score = 39.5 bits (88), Expect = 0.094
Identities = 22/70 (31%), Positives = 37/70 (52%)
Frame = +3
Query: 300 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 479
+LT + V V G++G+++ +G +I+ ST+ K+ + G+ DAPVSG
Sbjct: 65 MLTGEEAVDAVLFGEEGLLSGDCEGKTVINMSTVPVECSKRWAKELADHGMTLIDAPVSG 124
Query: 480 GVMGAQNATL 509
+ AQ TL
Sbjct: 125 SKVPAQTGTL 134
Score = 34.3 bits (75), Expect = 3.5
Identities = 17/47 (36%), Positives = 27/47 (57%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
+N+ F+GLG MG MAAN++K+G + Y+ + + A G A
Sbjct: 3 QNIGFIGLGIMGEAMAANILKQGHPLIVYNRTVEKAAALVDAGAMVA 49
>UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Burkholderia xenovorans (strain LB400)
Length = 302
Score = 46.8 bits (106), Expect = 6e-04
Identities = 25/64 (39%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
MA G E FE P L+V+G F+ G G GQ K+ NN L + +A+ E + G+K
Sbjct: 134 MAAGPMEAFETVEPWLRVIGKNIFYLGSGAGLGQTMKIINNTLCAVGMVASCEALVFGVK 193
Query: 692 MGLE 703
GL+
Sbjct: 194 AGLD 197
Score = 37.1 bits (82), Expect = 0.50
Identities = 22/64 (34%), Positives = 33/64 (51%)
Frame = +3
Query: 318 VVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQ 497
VV +V G GV + +++D ST P+V I ++ + F APVSGG + A+
Sbjct: 69 VVEEVATGPHGV-SQGSSVRIVVDLSTTGPSVSNVIARKLADRHIQFLGAPVSGGTVAAE 127
Query: 498 NATL 509
TL
Sbjct: 128 KGTL 131
>UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Rhizobiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 292
Score = 46.8 bits (106), Expect = 6e-04
Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Frame = +3
Query: 198 LRSFQRCTERSGQERSDA---SNSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAK 368
L+++ R RSD ++S+ ++L V V LG+DG+
Sbjct: 27 LKAYDRSPAALENLRSDGVTVADSLAAAVAGADVVVTMLPDTPHVQSVLLGEDGIGTLLP 86
Query: 369 KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 494
G+L+ID STI + + I +G+ DAPVSGGV GA
Sbjct: 87 TGTLVIDMSTISASGIRAIGQDLASRGVDLVDAPVSGGVRGA 128
Score = 46.0 bits (104), Expect = 0.001
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAE 670
+ M GG E F ++ P+L+ MG H G +G GQV K+ N +++G+ A E
Sbjct: 134 SIMCGGSPEAFAKARPVLEGMGTTIIHAGDLGMGQVFKMCNQLMVGVHIQAMCE 187
Score = 42.7 bits (96), Expect = 0.010
Identities = 23/48 (47%), Positives = 28/48 (58%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
+AF+G G MG M ANL K GF ++ YD S AL +GVT A L
Sbjct: 4 LAFIGAGVMGRPMIANLRKAGFALKAYDRSPAALENLRSDGVTVADSL 51
>UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Rhizobiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Methylobacterium sp. 4-46
Length = 299
Score = 46.8 bits (106), Expect = 6e-04
Identities = 26/48 (54%), Positives = 30/48 (62%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
VAF+GLG MG MA NLV KGF VRGYD ++ A A+ G A L
Sbjct: 6 VAFVGLGAMGLPMAQNLVAKGFPVRGYDVRPESRAALARAGGEAADTL 53
Score = 41.1 bits (92), Expect = 0.031
Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
MA E F PLL +GA+ FH G + G G K N +L G+ A AE +++ +
Sbjct: 142 MAAAPAEVFGAVRPLLDAVGARIFHVGTRPGQGATVKAVNQLLCGVHIAAAAEALSLAER 201
Query: 692 MGLE 703
+G++
Sbjct: 202 VGVD 205
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 46.4 bits (105), Expect = 8e-04
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +3
Query: 330 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
VY + G+ G +++D +T P + ++I A E G DAPVSGG +GA+N TL
Sbjct: 74 VYFNETGIFQADLTGKIVVDLTTSTPTLAEKIAKKAAEVGAHALDAPVSGGDLGAKNGTL 133
Score = 34.7 bits (76), Expect = 2.7
Identities = 18/62 (29%), Positives = 27/62 (43%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG +E ++ LP+ K G G G GQ K+ N +++ T E +
Sbjct: 136 MVGGDQESYDTVLPIFKTFGKTFMLHGSAGKGQHTKMANQLMIAGTMTGLTEMLVYANAT 195
Query: 695 GL 700
GL
Sbjct: 196 GL 197
>UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetella
bronchiseptica|Rep: Probable oxidoreductase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 316
Score = 46.4 bits (105), Expect = 8e-04
Identities = 24/41 (58%), Positives = 28/41 (68%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
+AFLGLG MG MA NLVK G V GYD + AL+A A+ G
Sbjct: 6 IAFLGLGAMGLPMACNLVKGGHAVTGYDLNPQALDALAQAG 46
Score = 38.7 bits (86), Expect = 0.16
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT-GMATAECMNMGIK 691
+A G +D R+ L MG + CG++G G K+ NN MGI+ TAE + +
Sbjct: 138 LASGSAQDKARARDALLCMGNQVIDCGEVGGGSRVKVVNN-FMGISLNALTAEALTLAEA 196
Query: 692 MGL 700
GL
Sbjct: 197 SGL 199
Score = 37.1 bits (82), Expect = 0.50
Identities = 21/57 (36%), Positives = 27/57 (47%)
Frame = +3
Query: 339 GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
G DG + G+L I+ STI P I E+G+ D+PV M AQ TL
Sbjct: 79 GADGALQGMDPGALFINMSTILPQETDLIAQRLAERGMRMLDSPVGRSAMEAQRGTL 135
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 46.4 bits (105), Expect = 8e-04
Identities = 23/63 (36%), Positives = 30/63 (47%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M G K F+R P+L +G FH G +G+G KL NN T A AE +
Sbjct: 144 MCSGDKATFDRVKPVLHTLGENVFHLGALGNGHTIKLINNCYSMTTACAMAEAFAIADAT 203
Query: 695 GLE 703
G+E
Sbjct: 204 GIE 206
Score = 33.1 bits (72), Expect = 8.2
Identities = 20/56 (35%), Positives = 31/56 (55%)
Frame = +3
Query: 306 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 473
TS +V +Y G DGV+A ++G ++ID T P ++I KG + DAP+
Sbjct: 75 TSAQVESRIY-GDDGVLAGTREGQVVIDFGTSLPASTRRIGGDLAGKGATYLDAPL 129
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 46.4 bits (105), Expect = 8e-04
Identities = 20/57 (35%), Positives = 33/57 (57%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMG 685
+ GG D +R++P+L+ +G H G +GSGQ K N +L+ + A AE + +G
Sbjct: 150 LCGGSDADLDRAMPVLETIGGSIHHFGAVGSGQQVKAVNQVLVAGSYAAVAEAIALG 206
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
++ + V V G +G +GSL+ID STI P+ +++ +G+ + DAPV+GG
Sbjct: 79 VSDDAAVEAVLWGDNGAGPALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYLDAPVTGG 138
Query: 483 VMGAQNATL 509
GA+ TL
Sbjct: 139 TEGAKAGTL 147
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 46.4 bits (105), Expect = 8e-04
Identities = 23/65 (35%), Positives = 36/65 (55%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+A G K ++ +P V+G K F G+IG+G KL NM+MG A +E +++
Sbjct: 135 LAAGDKVLYDDMVPAFDVLGKKSFFLGEIGNGAKMKLVVNMIMGSMMNALSEGLSLADNS 194
Query: 695 GLEPK 709
GL P+
Sbjct: 195 GLSPQ 199
Score = 42.3 bits (95), Expect = 0.013
Identities = 23/71 (32%), Positives = 35/71 (49%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L+ L V KDGV+ +G +D ST+D +I +KG F +APVS
Sbjct: 62 AMLSDPSAALSVVFDKDGVLEQIGEGKGYVDMSTVDAATSCKISEAIKQKGGAFVEAPVS 121
Query: 477 GGVMGAQNATL 509
G A++ L
Sbjct: 122 GSKKPAEDGQL 132
Score = 35.1 bits (77), Expect = 2.0
Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 4/49 (8%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTV----RGYDPSKDALNAAAKNGVTPA 255
V FLGLG MG MAANL++ GF V R ++ + A G TPA
Sbjct: 3 VGFLGLGIMGKAMAANLLRHGFRVTVWNRTLSKCQELVALGAAVGETPA 51
>UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza
sativa|Rep: Oxidoreductase-like - Oryza sativa subsp.
japonica (Rice)
Length = 341
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/65 (35%), Positives = 36/65 (55%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
F+ G + + R LL VMG +F G +G G KL NM+MG ++ +E + + K
Sbjct: 184 FLTAGDESLYNRVASLLDVMGKSRFFLGDVGKGADMKLVVNMVMGSMMVSFSEGLLLSEK 243
Query: 692 MGLEP 706
+GL+P
Sbjct: 244 VGLDP 248
Score = 33.9 bits (74), Expect = 4.7
Identities = 20/71 (28%), Positives = 31/71 (43%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L + ++V G +G G +D ST+D K I G F +APVS
Sbjct: 112 AMLADPESAVEVACGANGAAQGMAPGKGYVDVSTVDAATSKLIGKHITSTGASFLEAPVS 171
Query: 477 GGVMGAQNATL 509
G A++ L
Sbjct: 172 GSKKPAEDGLL 182
>UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase,
putative; n=1; Aspergillus fumigatus|Rep:
3-hydroxyisobutyrate dehydrogenase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 317
Score = 46.0 bits (104), Expect = 0.001
Identities = 21/41 (51%), Positives = 26/41 (63%)
Frame = +2
Query: 584 FHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEP 706
F CG G AKL NN G+ +ATAE MN+GIK G++P
Sbjct: 175 FPCGGFLLGLTAKLCNNYCSGLIAIATAEAMNIGIKSGMKP 215
Score = 37.5 bits (83), Expect = 0.38
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALE--KGLGFTDA 467
+++ + V VYL GV+ + +L+D STID + + K F DA
Sbjct: 84 TMVPEGRHVRSVYLDSHAGVLTTSVDDKILVDCSTIDTATSMDVGAAVCQNSKTAAFYDA 143
Query: 468 PVSGGVMGAQNATL 509
PVSGG +GA TL
Sbjct: 144 PVSGGSLGAVAGTL 157
>UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
2-hydroxy-3-oxopropionate reductase - Aurantimonas sp.
SI85-9A1
Length = 292
Score = 45.6 bits (103), Expect = 0.001
Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 479
LT++ V V G DG+VA K G ++D ST + V Q+ G F DAPVSG
Sbjct: 65 LTTSDAVASVVTGADGLVASRKLSGRTVVDFSTTEMAVTHQVAAAIEAVGGRFVDAPVSG 124
Query: 480 GVMGAQNATL 509
G A+ TL
Sbjct: 125 GPGAAETGTL 134
Score = 39.9 bits (89), Expect = 0.071
Identities = 21/65 (32%), Positives = 34/65 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M GG ++ E + P+L+ +G + H G IG+GQ KL N +L AE + +
Sbjct: 135 AIMFGGSEQAAEAARPMLEQLG-RATHMGAIGTGQATKLVNQVLCLTNYCVAAEALRLAQ 193
Query: 689 KMGLE 703
G++
Sbjct: 194 AYGVD 198
Score = 34.3 bits (75), Expect = 3.5
Identities = 18/48 (37%), Positives = 26/48 (54%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
+ F+GLG MG L + + V G+D + ++AAA GV PA L
Sbjct: 4 IGFIGLGLMGSGFTKRLRELDYRVIGHDREAEKVSAAAAWGVEPAGSL 51
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/91 (28%), Positives = 46/91 (50%)
Frame = +3
Query: 237 ERSDASNSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVP 416
E+ +NS+ + +++ V + GKD + ++ K G+L+ID +T +
Sbjct: 44 EQCTIANSLTDCGKHSEIIILCIGNDEDVRNTLTGKDSLYSNLKPGTLVIDHTTTSAELA 103
Query: 417 KQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
++ LEK + + DAPVSGG GA + L
Sbjct: 104 CEMQAKLLEKQVDYVDAPVSGGEQGAISGQL 134
Score = 35.9 bits (79), Expect = 1.2
Identities = 20/63 (31%), Positives = 32/63 (50%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG+ ER+ + + H G IGSGQ+ K+ N + + A AE ++ G +
Sbjct: 137 MCGGQALAAERAQGITQAYSKSFTHMGPIGSGQLTKMVNQICVAGLIEALAEGIHFGQQA 196
Query: 695 GLE 703
GL+
Sbjct: 197 GLD 199
>UniRef50_Q8TUC1 Cluster: Predicted protein; n=4;
Methanosarcinaceae|Rep: Predicted protein -
Methanosarcina acetivorans
Length = 259
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Frame = +1
Query: 64 TQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN- 240
T +Y Y K+V +GLG +G AA+LV KGF V GYD K L +
Sbjct: 125 TGIIYAEIASRYMKADSKDVLAVGLGKVGFPGAAHLVNKGFRVYGYDADKALLEKTVSDL 184
Query: 241 GVTPATP 261
G+TP P
Sbjct: 185 GITPFEP 191
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 45.6 bits (103), Expect = 0.001
Identities = 24/63 (38%), Positives = 35/63 (55%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V +V G++G + KG ++D S+I P K+ E G + DAPVSGG +GA+
Sbjct: 69 VEEVLFGENGCTKASLKGKTIVDMSSISPIETKRFARQVNELGGDYLDAPVSGGEIGARE 128
Query: 501 ATL 509
TL
Sbjct: 129 GTL 131
Score = 41.9 bits (94), Expect = 0.018
Identities = 22/73 (30%), Positives = 35/73 (47%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G E + M GG + FER PL +++G G G GQ K+ N +++ + A +
Sbjct: 125 GAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVGGNGDGQTCKVANQIIVALNIEAVS 184
Query: 668 ECMNMGIKMGLEP 706
E + K G +P
Sbjct: 185 EALLFASKAGADP 197
>UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL
B-14911|Rep: Oxidoreductase - Bacillus sp. NRRL B-14911
Length = 270
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/71 (35%), Positives = 40/71 (56%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
SIL ++K + V L ++ V+ G LI+ ++ P + K++ +KG+ D PVS
Sbjct: 49 SILPADKEMESVLLSEE-VLNVLNPGQFLIEMTSGSPEMMKKVHAAYQQKGIPVLDGPVS 107
Query: 477 GGVMGAQNATL 509
GG GA+N TL
Sbjct: 108 GGTAGAENGTL 118
Score = 43.2 bits (97), Expect = 0.008
Identities = 22/63 (34%), Positives = 33/63 (52%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
MAGG + ER P+L+ M + G +G G+ K N ML GI A AE + + K+
Sbjct: 121 MAGGDADVLERLRPVLESMATNIYLVGSVGDGKAIKAINQMLAGIHMAAAAEAVALAEKL 180
Query: 695 GLE 703
++
Sbjct: 181 EID 183
>UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Sagittula stellata E-37|Rep: Probable
6-phosphogluconate dehydrogenase protein - Sagittula
stellata E-37
Length = 298
Score = 45.2 bits (102), Expect = 0.002
Identities = 20/55 (36%), Positives = 32/55 (58%)
Frame = +2
Query: 542 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEP 706
ER+ +L +G + FH G +G+G K NN + +A AE M +G ++GL+P
Sbjct: 150 ERTRAVLSCLGNRLFHLGPVGAGHAMKALNNYVSAAGYVAAAEAMIIGTEVGLDP 204
Score = 41.5 bits (93), Expect = 0.023
Identities = 24/51 (47%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Frame = +1
Query: 112 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA-AAKNGV-TPAT 258
DK + F+GLGNMG MA +LV+ GF V YD + A A + G+ PAT
Sbjct: 3 DKLIGFIGLGNMGTAMARHLVRGGFEVLAYDIDAEKRAAFAEETGMRNPAT 53
Score = 40.7 bits (91), Expect = 0.041
Identities = 18/57 (31%), Positives = 33/57 (57%)
Frame = +3
Query: 339 GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
G+ G++ + G+L+ID+++ P +++ + +G DAPVSG GA+ A L
Sbjct: 81 GEAGLLGQMQPGTLMIDTTSSPPEATRELAAVLNARGCHLVDAPVSGARAGAEAADL 137
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/65 (35%), Positives = 33/65 (50%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A MAG + D R P+L+ MGA H G +GS K NN + +A +E M +
Sbjct: 143 AIMAGAAEADLRRVRPILERMGAAIIHTGAVGSAHAMKALNNYVYAAGLLAVSEAMVIAR 202
Query: 689 KMGLE 703
+M L+
Sbjct: 203 RMELD 207
Score = 35.5 bits (78), Expect = 1.5
Identities = 17/57 (29%), Positives = 30/57 (52%)
Frame = +3
Query: 339 GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
G+ G++ + G+ ++D + +P +++ +GL DAPVSG V A TL
Sbjct: 86 GQPGLIDLLESGAAIVDMGSSNPADTRRLSEQLAARGLTLIDAPVSGAVAKASTGTL 142
>UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
2-hydroxy-3-oxopropionate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 293
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/66 (34%), Positives = 35/66 (53%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A MAGG + R P+ +G + G IG+GQ+AKL N +++G+T A +E +
Sbjct: 132 AIMAGGEEAVLNRLAPVFAALG-RMTRIGDIGAGQLAKLANQLIVGVTIGAVSEAFVLAE 190
Query: 689 KMGLEP 706
G P
Sbjct: 191 AGGASP 196
>UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Solibacter usitatus Ellin6076|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Solibacter usitatus (strain Ellin6076)
Length = 267
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/54 (35%), Positives = 31/54 (57%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECM 676
MAGGR+E F+ + PL + ++ F+ G G+G KL N+ +G+ AE +
Sbjct: 115 MAGGRRESFDAASPLFRTFASRAFYLGPFGAGARMKLVVNLALGLHRAVLAETL 168
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/60 (38%), Positives = 31/60 (51%)
Frame = +3
Query: 330 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
V G+ GV KG +++D S+I P K G + DAPVSGG +GA+ TL
Sbjct: 75 VLFGEHGVAHGLSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAPVSGGQVGAKGGTL 134
Score = 42.3 bits (95), Expect = 0.013
Identities = 20/64 (31%), Positives = 33/64 (51%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG++ F+ P+ +MG G G+GQV K+ N +++ + A AE + K
Sbjct: 137 MVGGKESVFQTVKPMFDLMGKNITLVGDNGAGQVTKVANQIIVALNIEAVAEALLFASKA 196
Query: 695 GLEP 706
G +P
Sbjct: 197 GADP 200
>UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Stappia aggregata IAM
12614|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Stappia aggregata IAM 12614
Length = 291
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/71 (30%), Positives = 37/71 (52%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L + VY G DG+ + +L++ T+ + +++ A EKG F DAPVS
Sbjct: 63 TMLADDAAAETVYFGPDGLFEASSGAQVLVEMGTLSVPMAERLARAAQEKGRRFVDAPVS 122
Query: 477 GGVMGAQNATL 509
G A++A L
Sbjct: 123 GATQAAKDAKL 133
Score = 33.5 bits (73), Expect = 6.2
Identities = 19/62 (30%), Positives = 27/62 (43%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
MAG D L V+G K G+ G+G KL NML+ AE +++
Sbjct: 136 MAGATASDAPELAALFDVLGRKTIWLGKAGAGAAMKLGVNMLIHGLNQTLAEALSLTTAA 195
Query: 695 GL 700
G+
Sbjct: 196 GI 197
>UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Proteobacteria|Rep: 3-hydroxyacid dehydrogenase -
Neisseria meningitidis serogroup B
Length = 289
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/61 (36%), Positives = 32/61 (52%)
Frame = +2
Query: 521 GGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGL 700
GG + + ++G K FH G +G G AKL N L+GI G A +E M M + G+
Sbjct: 139 GGSEAVLNPLQKIFSLVGKKTFHFGDVGKGSGAKLVLNSLLGIFGEAYSEAMLMARQFGI 198
Query: 701 E 703
+
Sbjct: 199 D 199
Score = 33.1 bits (72), Expect = 8.2
Identities = 17/46 (36%), Positives = 24/46 (52%)
Frame = +3
Query: 372 GSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
G ++++ STI P + + G F +APVSG V A N TL
Sbjct: 89 GKIIVNMSTISPTENLAVKALVEAAGGQFAEAPVSGSVGPATNGTL 134
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 44.4 bits (100), Expect = 0.003
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = +3
Query: 330 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
+ GKDGV K S+ + S+T+DP+V +++ G + DAP+SGG A L
Sbjct: 81 ILFGKDGVAETMPKDSVFLSSATMDPDVARRLAKQLEATGRHYLDAPISGGAQRAAQGEL 140
Score = 39.1 bits (87), Expect = 0.12
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGMATAECMNMGIK 691
+A G F ++ P L M AK + G G G K+ N +L G+ A +E M K
Sbjct: 143 LASGSPAAFAKARPALDAMAAKLYELGDAAGQGAAFKMINQLLAGVHIAAASEAMAFAAK 202
Query: 692 MGLE 703
GL+
Sbjct: 203 QGLD 206
Score = 38.7 bits (86), Expect = 0.16
Identities = 19/48 (39%), Positives = 30/48 (62%)
Frame = +1
Query: 100 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
S++ ++ +A +GLG+MG MA +L + G V G D S DA+ K+G
Sbjct: 4 STSQNQRIAVVGLGSMGFGMATSLKRAGHAVTGCDVSADAVARFVKDG 51
>UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Chromobacterium violaceum|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/64 (34%), Positives = 32/64 (50%)
Frame = +2
Query: 485 HGCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAT 664
H S F+ GG + D E + PLL +G H G +G+G AKL N+L+G+
Sbjct: 132 HDASHGTLHFLVGGAEADVEWASPLLWALGRGVHHLGGLGAGNTAKLALNLLVGVMAGGL 191
Query: 665 AECM 676
E +
Sbjct: 192 GEAI 195
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/66 (37%), Positives = 35/66 (53%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A MAGG +DF + +L VMG G G GQ+AKL N +++G T AE + +
Sbjct: 137 AIMAGGSAQDFAEAEAVLTVMGRPTL-VGPAGCGQIAKLCNQLIVGGTLNIVAEALLLAQ 195
Query: 689 KMGLEP 706
G +P
Sbjct: 196 AGGADP 201
Score = 41.5 bits (93), Expect = 0.023
Identities = 20/55 (36%), Positives = 33/55 (60%)
Frame = +3
Query: 345 DGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
D + K G+L+ID S+ + +++ +G+ F DAPVSGGV+GA+ +L
Sbjct: 82 DAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSGGVVGAEAGSL 136
>UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 279
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/57 (38%), Positives = 32/57 (56%)
Frame = +3
Query: 339 GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
G DG+ + GSL+I+ STI P ++ L KG G+ D PVSG ++ A+ L
Sbjct: 64 GPDGIARGLRPGSLVINMSTIAPEEAQEEALSLLAKGAGYLDVPVSGSLVPAEKGEL 120
Score = 40.7 bits (91), Expect = 0.041
Identities = 22/63 (34%), Positives = 33/63 (52%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+AGG ER+ P+L G K H G GSG AKL N+L+ + + + +G +
Sbjct: 123 LAGGDGAALERARPILLHFGKKILHFGPTGSGMKAKLVINLLLASHVESLVQTVLVGESL 182
Query: 695 GLE 703
GL+
Sbjct: 183 GLD 185
>UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 272
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/63 (38%), Positives = 34/63 (53%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V +V G+ GV+A G ++ ST+ P+ +I EKG+ DAPVSGG A+
Sbjct: 70 VREVLDGETGVLAGLAPGGIIAIHSTVHPDTCTEIAEQVAEKGISLIDAPVSGGEPAAKA 129
Query: 501 ATL 509
TL
Sbjct: 130 GTL 132
Score = 39.1 bits (87), Expect = 0.12
Identities = 19/62 (30%), Positives = 31/62 (50%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
MAGG ++ ++ P+ G +GSGQVAK+ NN+L A + +G +
Sbjct: 135 MAGGDEDIVDKVRPVFATYADPVVRLGGVGSGQVAKILNNLLFSANLGAAMSALELGEAL 194
Query: 695 GL 700
G+
Sbjct: 195 GV 196
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/64 (39%), Positives = 32/64 (50%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
F+AGG +R PLL MG+ CG +G G KL N+LM A AE + +
Sbjct: 135 FLAGGHHAVIQRCEPLLLSMGSAVIPCGAVGDGTRMKLAMNLLMSGMVQALAESLLLVRN 194
Query: 692 MGLE 703
GLE
Sbjct: 195 SGLE 198
Score = 37.9 bits (84), Expect = 0.29
Identities = 21/63 (33%), Positives = 33/63 (52%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
+L+V G GV + G ++I++ST+ +Q + + G F DAPVSG + AQ
Sbjct: 71 LLEVLQGPVGVCSADLTGKVVINASTVSVEASQQAATLVEQVGGAFLDAPVSGSKIPAQT 130
Query: 501 ATL 509
L
Sbjct: 131 GKL 133
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 44.4 bits (100), Expect = 0.003
Identities = 26/69 (37%), Positives = 36/69 (52%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L + + V LG DG + +L+D ST+ V K++ L KG+ DAPVSGG
Sbjct: 76 LPTPAIFRQVALG-DGGLIEGSAIKVLVDLSTVGSRVEKEVAQGLLAKGVETVDAPVSGG 134
Query: 483 VMGAQNATL 509
GA+ TL
Sbjct: 135 AAGAKKGTL 143
Score = 40.7 bits (91), Expect = 0.041
Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMG 685
A MA G E L V+G K F G + G GQ+ KL NNML T+E G
Sbjct: 144 AIMAAGSPVALEEVRGLFDVLG-KAFVVGDKAGQGQLLKLLNNMLSSTAFAITSEAFVAG 202
Query: 686 IKMGLEPK 709
++ GL+P+
Sbjct: 203 VRGGLDPE 210
>UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Sulfolobus solfataricus
Length = 289
Score = 44.4 bits (100), Expect = 0.003
Identities = 23/65 (35%), Positives = 34/65 (52%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ GG K+ F+ + K + + G G G +KL NN+L+ A AE N GI+
Sbjct: 132 LVGGPKDKFDIVNDIAKETASLVVYMGPNGMGLYSKLVNNLLLASYVAAIAEAYNFGIRA 191
Query: 695 GLEPK 709
GLEP+
Sbjct: 192 GLEPQ 196
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 44.4 bits (100), Expect = 0.003
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 479
LT V V G+DG++ AKKG L ID STIDP+ + A + GL D PV G
Sbjct: 73 LTDEAAVNSVAFGEDGLLNGAKKGCLWIDLSTIDPSSSVKHAEAAKKAGLERLDTPVVG 131
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 44.0 bits (99), Expect = 0.004
Identities = 27/71 (38%), Positives = 40/71 (56%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L+ V +V L + GV KG+++IDSS+I P + ++ G+ DAPVS
Sbjct: 71 TMLSDGNAVGEV-LFEAGVAEALAKGAVVIDSSSIAPPIAREHSSRLQAMGIHHVDAPVS 129
Query: 477 GGVMGAQNATL 509
GGV GA TL
Sbjct: 130 GGVPGATAGTL 140
Score = 38.3 bits (85), Expect = 0.22
Identities = 21/50 (42%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG-VTPATP 261
++VAF+G G MGG MA L+ GF+V+ ++ S D A +G V A+P
Sbjct: 10 RSVAFIGTGLMGGPMARRLLGTGFSVKVWNRSVDKAQALVADGAVLAASP 59
>UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderia sp. 383|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 303
Score = 44.0 bits (99), Expect = 0.004
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L + V L V LG DGVV H L ++ STI ++ ++I ++G+ DAPVSGG
Sbjct: 68 LPNRDVSLAVGLGPDGVV-HGSAVRLYVEMSTIGQDMIERIGEGLAQRGIDIVDAPVSGG 126
Query: 483 VMGAQNATL 509
A+ TL
Sbjct: 127 PSAARAGTL 135
Score = 39.5 bits (88), Expect = 0.094
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMG 685
A + G E+ PLL+ +G + F G + G Q+ K+ NN++M + AE + MG
Sbjct: 136 AMLVSGMPSAVEQVSPLLERIGKEVFPMGDRPGMAQIMKIVNNVVMAANLVVCAEGLAMG 195
Query: 686 IKMGLE 703
K GL+
Sbjct: 196 AKAGLD 201
Score = 34.3 bits (75), Expect = 3.5
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
Frame = +1
Query: 118 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG-VTPATP 261
++ FLGLG MG MA L+ + + YDPS A+ G V A+P
Sbjct: 6 DIGFLGLGKMGAPMAERLLGQACRLHVYDPSAQAVAPFVDGGAVAHASP 54
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/63 (38%), Positives = 34/63 (53%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V ++YL DG++ K G++LID +T P + + I A G D PV+GG GA
Sbjct: 74 VEELYLAGDGLLTCTKPGAVLIDLTTSSPELARDIAEAAQVSGRMAFDCPVTGGESGAIA 133
Query: 501 ATL 509
TL
Sbjct: 134 GTL 136
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 44.0 bits (99), Expect = 0.004
Identities = 20/54 (37%), Positives = 33/54 (61%)
Frame = +3
Query: 348 GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
G +A G +L+D ++ DP + +++ A +G DAPVSGG +GA++ TL
Sbjct: 95 GALAAIPPGGVLVDCTSSDPALAREVAAAARARGCWAVDAPVSGGDVGARDGTL 148
Score = 33.5 bits (73), Expect = 6.2
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A +AGG + PL + +G + G GSGQ +K+ N + +G T + +E +
Sbjct: 149 AILAGGDEGVVHWLSPLFEALGRATW-MGPAGSGQSSKIANQITIGGTILGLSEAIVFAG 207
Query: 689 KMGLE-PKF 712
+ GL+ P+F
Sbjct: 208 RAGLDVPRF 216
>UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=6; Saccharomycetales|Rep:
3-hydroxyisobutyrate dehydrogenase-like protein - Pichia
stipitis (Yeast)
Length = 355
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Frame = +2
Query: 557 LLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 709
LL MGA F CG+ G+G AKL+NN L+ +T +A A+ + GL K
Sbjct: 192 LLNKMGANIFACGETHGAGLAAKLSNNYLLAVTNLAVADSFQLAKSFGLNLK 243
Score = 38.7 bits (86), Expect = 0.16
Identities = 20/44 (45%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +3
Query: 384 IDSSTIDPNVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATL 509
+DSSTID +++ ++ G F D PVSGGV GA+ ATL
Sbjct: 130 LDSSTIDIPTSREVHEFVKKELPGADFIDTPVSGGVAGARKATL 173
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 43.6 bits (98), Expect = 0.006
Identities = 22/77 (28%), Positives = 37/77 (48%)
Frame = +2
Query: 473 IWRSHGCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 652
++ G E + GG + + P+L+ H G +GSGQVAK NNML
Sbjct: 118 VFGRQGAKEGQLGSLCGGDDKQVAKITPVLESYSKAVHHVGPVGSGQVAKACNNMLHWAA 177
Query: 653 GMATAECMNMGIKMGLE 703
+A E +++ + G++
Sbjct: 178 CVANFEVLSLAKRYGID 194
Score = 35.5 bits (78), Expect = 1.5
Identities = 17/55 (30%), Positives = 32/55 (58%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQPLMES 285
V+ +G+G+MG +A ++ KG V YD S++ + AKNG+ L + + ++
Sbjct: 3 VSIIGVGDMGRDIAVHVRDKGHDVIAYDISEERRSDVAKNGIKVVESLAEAVAKA 57
Score = 33.1 bits (72), Expect = 8.2
Identities = 18/48 (37%), Positives = 25/48 (52%)
Frame = +3
Query: 372 GSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLPS 515
GS ++ +T P + + +KGLGF DAPV G GA+ L S
Sbjct: 84 GSTVVILATNSPKTMQVLAAECEDKGLGFVDAPVVFGRQGAKEGQLGS 131
>UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=24;
Gammaproteobacteria|Rep: Uncharacterized oxidoreductase
yihU - Salmonella typhimurium
Length = 298
Score = 43.6 bits (98), Expect = 0.006
Identities = 19/46 (41%), Positives = 29/46 (63%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAT 258
+AF+GLG MG MA+NL+K+G + +D + DA+ G PA+
Sbjct: 4 IAFIGLGQMGSPMASNLLKQGHQLSVFDVNPDAVQRLVDKGAQPAS 49
Score = 35.9 bits (79), Expect = 1.2
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+AGG E ER+ P+L MG + + G G G KL NN + +AE + +
Sbjct: 136 LAGGTAEQVERATPVLMAMGNELVNTGGPGMGIRVKLINNYMSIALNALSAEAAVLCEAL 195
Query: 695 GL 700
GL
Sbjct: 196 GL 197
Score = 33.1 bits (72), Expect = 8.2
Identities = 20/71 (28%), Positives = 30/71 (42%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L + +V V G+ GV + +L+ID STI P + KG D P+
Sbjct: 63 TMLPNGDLVRSVLFGEQGVCETLSREALVIDMSTIHPLQTDNLIADMQSKGFSMMDVPIG 122
Query: 477 GGVMGAQNATL 509
A TL
Sbjct: 123 RTSDNAITGTL 133
>UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Aquifex aeolicus
Length = 288
Score = 43.2 bits (97), Expect = 0.008
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ GG KE FE + PL + ++ G+ G G KL NN+++G AE + +G K
Sbjct: 136 VVGGDKEKFEENKPLFEKFCRAIYYLGEAGMGSKMKLVNNIVLGGIMEVLAEAIAIGEKA 195
Query: 695 GLE 703
G++
Sbjct: 196 GID 198
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 43.2 bits (97), Expect = 0.008
Identities = 19/43 (44%), Positives = 29/43 (67%)
Frame = +3
Query: 381 LIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
++D+STI + ++I + G+G+ DAPVSGGV GA+ TL
Sbjct: 88 VVDTSTIGVSAAQRITDLLAASGIGYVDAPVSGGVTGARARTL 130
Score = 33.9 bits (74), Expect = 4.7
Identities = 15/32 (46%), Positives = 22/32 (68%)
Frame = +1
Query: 109 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYD 204
T +V F+GLGNMGG +AAN+ + G + +D
Sbjct: 2 TAPSVGFVGLGNMGGALAANVAQFGLDLVVHD 33
>UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 307
Score = 43.2 bits (97), Expect = 0.008
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +3
Query: 309 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 488
S+ V LG+ G +A +G+L+ID T + +Q+ +G F DAP++G +
Sbjct: 78 SDAATFAVLLGEGGALAGVGQGALVIDCGTTSLKLTEQLAAACEGEGASFLDAPITGSKL 137
Query: 489 GAQNATL 509
GA+ L
Sbjct: 138 GAEGGKL 144
Score = 34.7 bits (76), Expect = 2.7
Identities = 17/38 (44%), Positives = 21/38 (55%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAA 234
+AFLG G MG M NL G +R Y+ +K AAA
Sbjct: 4 IAFLGTGTMGAGMVRNLAAAGHELRIYNRTKSRAEAAA 41
Score = 33.5 bits (73), Expect = 6.2
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGI 649
M G +E R++PL ++MG H + +G GQ AK NM +
Sbjct: 147 MVAGEEEIVARAMPLFEIMGKHTVHVSERLGDGQRAKYCLNMTQAV 192
>UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyisobutirate dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 300
Score = 42.7 bits (96), Expect = 0.010
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
MA G +ER+ PLL +G F+ G + GQ KL NN L +A+ E + G K
Sbjct: 137 MAAGPLAAYERARPLLDAVGRHIFYLGGDVRLGQTLKLINNTLYASAMLASCEALVCGAK 196
Query: 692 MGLEPK 709
GL+ +
Sbjct: 197 AGLDAR 202
>UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 294
Score = 42.7 bits (96), Expect = 0.010
Identities = 21/70 (30%), Positives = 33/70 (47%)
Frame = +2
Query: 494 SERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAEC 673
++R M GG + R P+L+ H G +GSGQVAKL NN + E
Sbjct: 142 AQRRLLVMVGGEDDAVARCRPVLETFACPVIHLGPLGSGQVAKLVNNFVFTAQVGLALET 201
Query: 674 MNMGIKMGLE 703
+ ++G++
Sbjct: 202 FSFAQRLGMD 211
Score = 39.5 bits (88), Expect = 0.094
Identities = 21/54 (38%), Positives = 31/54 (57%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
V DV L DGV+A G +++ STI P +++ A ++ + DAPVSGG
Sbjct: 84 VEDVLLRADGVLAGMAAGGVVVIHSTIRPETCQRLATEAAKQEISIIDAPVSGG 137
>UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 282
Score = 42.7 bits (96), Expect = 0.010
Identities = 19/66 (28%), Positives = 34/66 (51%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
FM G + E ++ PL MG K H G++G GQ +K++ N+ + E + +
Sbjct: 129 FMVGAKDETLKKLEPLFLQMGKKIVHMGEVGKGQASKISLNLQIACIYEGFIEGFKVATQ 188
Query: 692 MGLEPK 709
+G+ P+
Sbjct: 189 LGVNPE 194
Score = 41.5 bits (93), Expect = 0.023
Identities = 22/69 (31%), Positives = 35/69 (50%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
++ V V G GV + G +++DSSTI P + KG + DAP++G
Sbjct: 59 VSDTNAVERVLFGDGGVEPVLRAGMVVVDSSTISPVETLKFAERVRAKGADYIDAPITGS 118
Query: 483 VMGAQNATL 509
+GA++A L
Sbjct: 119 KIGAESAQL 127
>UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 311
Score = 42.7 bits (96), Expect = 0.010
Identities = 23/63 (36%), Positives = 31/63 (49%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG+KE FER P+L+ M A G G K NM+M I AE + + +
Sbjct: 145 MVGGKKEAFERVRPVLEAMSASLRWIGPAGQAAKIKALVNMVMNINTAGLAEGLGLADAL 204
Query: 695 GLE 703
GL+
Sbjct: 205 GLD 207
>UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: 3-hydroxyisobutyrate
dehydrogenase - Microscilla marina ATCC 23134
Length = 295
Score = 42.7 bits (96), Expect = 0.010
Identities = 21/67 (31%), Positives = 34/67 (50%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
F+ GG ++ P +++MG K H G I K+ N L+ +A AE + +G K
Sbjct: 134 FLVGGGTTAIAQATPYMEMMGKKVVHIGAISKASALKILINYLLAQGMLAFAEALVVGEK 193
Query: 692 MGLEPKF 712
GL+ +F
Sbjct: 194 QGLDRRF 200
Score = 39.5 bits (88), Expect = 0.094
Identities = 26/71 (36%), Positives = 37/71 (52%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S+L S +VV V G+ G ++ K +L ID STI P A + + F +APV+
Sbjct: 62 SMLASPQVVKAVAYGQTGFLSKMKSKALWIDCSTISPAFALASAQEASKHEVVFVEAPVA 121
Query: 477 GGVMGAQNATL 509
G A+NA L
Sbjct: 122 GTKSHAENAEL 132
>UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 42.7 bits (96), Expect = 0.010
Identities = 19/62 (30%), Positives = 31/62 (50%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG + D E++ P+ H G +GSGQV K+ NN+L + + +G +
Sbjct: 135 MVGGEEADVEKARPVFATYADPIVHLGPLGSGQVTKILNNLLFTANLGSALSTLELGESL 194
Query: 695 GL 700
G+
Sbjct: 195 GI 196
Score = 38.7 bits (86), Expect = 0.16
Identities = 20/63 (31%), Positives = 32/63 (50%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V +V G GV+A G+++ ST+ P+ ++I A + + DAPVSGG +
Sbjct: 70 VREVLYGDTGVLAGLAPGAMIAIHSTVHPDTCREIAEKAAAQNVSVIDAPVSGGAPAVEQ 129
Query: 501 ATL 509
L
Sbjct: 130 GKL 132
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 42.7 bits (96), Expect = 0.010
Identities = 18/52 (34%), Positives = 29/52 (55%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQ 270
+ + F+GLGNMGG M LV G +V GYD + + + AA + +++
Sbjct: 4 ERIGFIGLGNMGGRMTRRLVDAGISVLGYDTAPERVKAAGAQAASSIADVMK 55
Score = 40.7 bits (91), Expect = 0.041
Identities = 26/101 (25%), Positives = 44/101 (43%)
Frame = +3
Query: 207 FQRCTERSGQERSDASNSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLI 386
+ ER + A++SI L +KVV V G GV+AH + +++
Sbjct: 32 YDTAPERVKAAGAQAASSIADVMKFADVVMMSLPDSKVVEAVVEGDGGVLAHCRARQIVV 91
Query: 387 DSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
D ST + ++ + G+ + DA +SGG A+ L
Sbjct: 92 DLSTAAASSTIRLARRFTQSGVQYVDAGISGGAAAAEKGAL 132
Score = 37.5 bits (83), Expect = 0.38
Identities = 18/45 (40%), Positives = 26/45 (57%)
Frame = +2
Query: 569 MGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLE 703
+ +K H G+ G+G KL NN L ++ A+AE M G K GL+
Sbjct: 153 ISSKVAHMGESGAGHTTKLLNNFLNAVSLSASAEVMVAGKKAGLD 197
>UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1;
Gluconobacter oxydans|Rep: Putative oxidoreductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 290
Score = 42.3 bits (95), Expect = 0.013
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +3
Query: 339 GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
G++G +A G L++D+ST+ P+ +A+E G DAP+SG A+ L
Sbjct: 73 GENGALAALTPGKLVLDTSTVSPDQADAFASLAVEHGFSLLDAPMSGSTPEAETGDL 129
Score = 40.7 bits (91), Expect = 0.041
Identities = 22/63 (34%), Positives = 33/63 (52%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ GG + +R+ P+L V+G H G GS KL N +MG T AE ++ G+
Sbjct: 132 LVGGDEAVVKRAQPVLDVIGKLTIHAGPAGSAARLKLVVNGVMGATLNVIAEGVSYGLAA 191
Query: 695 GLE 703
GL+
Sbjct: 192 GLD 194
>UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobacter
sp. BP2|Rep: Putative oxidoreductase - Arthrobacter sp.
BP2
Length = 278
Score = 42.3 bits (95), Expect = 0.013
Identities = 22/50 (44%), Positives = 28/50 (56%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
K + F+GLG MG MA NL + GF V GYD + + A G+T A L
Sbjct: 3 KKIGFVGLGTMGLPMAVNLNRAGFEVIGYDAFEGSRQKAIAAGITMAETL 52
Score = 40.3 bits (90), Expect = 0.054
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMG 685
+ MA G ++ + P +G+ F+ G + G+ Q AKL NN+++GI A AE + G
Sbjct: 137 SIMASGAEDVVTAASPYFDAVGSNTFYYGSKPGNSQAAKLVNNLVLGINMNAVAEGLKFG 196
Query: 686 IKMGL 700
+ L
Sbjct: 197 AQYNL 201
Score = 38.7 bits (86), Expect = 0.16
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Frame = +3
Query: 324 LDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTDAPVSGGVMGAQN 500
+DV LG+DG+++ K +I ST+DP+ ++ E G + A VSGG GA+
Sbjct: 74 VDVILGQDGLLSANPKNLTIIVMSTLDPDTMNELGQQVEEHGEVRLIAAAVSGGSTGAEA 133
Query: 501 ATL 509
TL
Sbjct: 134 GTL 136
>UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=17; Proteobacteria|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 325
Score = 42.3 bits (95), Expect = 0.013
Identities = 21/70 (30%), Positives = 36/70 (51%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQPLMESTWSFP 300
+ F+GLGN+GG +A +L++ GF + YD + D + + G P T L +
Sbjct: 3 IGFIGLGNVGGKLAGSLLRNGFDLTVYDLNPDLVAEYVEKGAQPGTGPLAIMRACDAVIT 62
Query: 301 Y*PAIKSCST 330
P+ +C+T
Sbjct: 63 CLPSPAACAT 72
Score = 37.9 bits (84), Expect = 0.29
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 640
+ AG + FER LP L +G + H G IGS + K+ N L
Sbjct: 130 SIFAGCDRATFERMLPTLTTLGRRVLHTGDIGSASILKVMTNYL 173
>UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Verminephrobacter eiseniae
(strain EF01-2)
Length = 297
Score = 42.3 bits (95), Expect = 0.013
Identities = 23/65 (35%), Positives = 34/65 (52%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M G E F PL+ + CG +G GQV K+ NNM++ T +A +E +G
Sbjct: 140 AVMVGADPELFGVIEPLIATFASDIALCGPVGCGQVLKILNNMILFETVVAISEAKAIGE 199
Query: 689 KMGLE 703
K G++
Sbjct: 200 KAGVD 204
Score = 34.3 bits (75), Expect = 3.5
Identities = 20/69 (28%), Positives = 34/69 (49%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L S +V + +DG++A A+ G +++D T + +Q+ + F DAPV+
Sbjct: 71 LPSGAIVAQLCRQQDGLLASARPGHIVVDLGTSSVDGTRQLAAEFAARQAKFADAPVART 130
Query: 483 VMGAQNATL 509
AQ TL
Sbjct: 131 RAAAQAGTL 139
>UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 297
Score = 42.3 bits (95), Expect = 0.013
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 6/110 (5%)
Frame = +3
Query: 198 LRSFQRCTERSGQERSDASNSIXXXXXXXXXXXS-----ILTSNKVVLDVYLGKDGVVAH 362
LR + R E++ ++ A+N + + L V V G DG+
Sbjct: 29 LRVWNRSNEKAAALQASATNCVACESPAQVAAGAGIVMLCLADAAAVEAVAFGVDGLANR 88
Query: 363 AKKGSLLIDSSTIDPNVPKQIFPIALEK-GLGFTDAPVSGGVMGAQNATL 509
A++G+ L+D ST+ P+ + E+ G + DAPVSGG GA TL
Sbjct: 89 ARRGATLVDHSTLAPSQTRAFARRWREQTGGDWIDAPVSGGTSGAAAGTL 138
Score = 36.7 bits (81), Expect = 0.66
Identities = 21/65 (32%), Positives = 30/65 (46%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A MAGG E P+L+ A+ G G+GQ KL N ++ T A AE +
Sbjct: 139 AIMAGGDATLIETLTPILRGYAARVTRMGGSGAGQATKLANQTIVMTTIAALAEATRLAR 198
Query: 689 KMGLE 703
G++
Sbjct: 199 HAGID 203
>UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=17;
Pyrococcus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pyrococcus furiosus
Length = 278
Score = 42.3 bits (95), Expect = 0.013
Identities = 21/62 (33%), Positives = 32/62 (51%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ G +E FER P L+ +G + F+ + G KL NN ++G A E + +G K
Sbjct: 126 LVSGEREAFERVRPYLQKLGKRIFYFNEPGKATKLKLINNFVLGAFMAALGEAIALGEKA 185
Query: 695 GL 700
GL
Sbjct: 186 GL 187
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 41.9 bits (94), Expect = 0.018
Identities = 22/63 (34%), Positives = 34/63 (53%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ G D ER+ P L+ +G+ H G +GSG V KL NN++ I AE + + +
Sbjct: 136 LVGADAADLERARPYLEPIGSTIRHFGAVGSGTVYKLINNLMGAIQIAGLAEGLAIAEQA 195
Query: 695 GLE 703
GL+
Sbjct: 196 GLD 198
Score = 33.1 bits (72), Expect = 8.2
Identities = 19/46 (41%), Positives = 23/46 (50%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAT 258
VAF+GLG MG MA + GFTV ++ SK G AT
Sbjct: 4 VAFIGLGRMGHGMAGRYLDAGFTVTLWNRSKTKAEDLIARGAHWAT 49
>UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=8; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 292
Score = 41.9 bits (94), Expect = 0.018
Identities = 22/48 (45%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP-ATP 261
VA LG+G MG +A NL ++GFTVR ++ ++ +A A +GV ATP
Sbjct: 12 VAVLGIGVMGAPIARNLARQGFTVRAWNRTRAKADALAADGVAAFATP 59
>UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Frankia sp. CcI3|Rep:
6-phosphogluconate dehydrogenase, NAD-binding - Frankia
sp. (strain CcI3)
Length = 290
Score = 41.9 bits (94), Expect = 0.018
Identities = 19/46 (41%), Positives = 26/46 (56%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAT 258
+ F+GLG MG MA NL+ G TV ++ S D + A G PA+
Sbjct: 3 IGFIGLGGMGSAMARNLIDAGHTVLAWNRSPDPVTELAAAGAVPAS 48
>UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 332
Score = 41.9 bits (94), Expect = 0.018
Identities = 24/71 (33%), Positives = 36/71 (50%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
++L + K V V +G G++A G +D ST P V ++ +G+ DAPVS
Sbjct: 85 TMLPTPKHVETVAMGPGGILAGMPDGGTWVDMSTSVPEVANRVREAGSVRGIRVLDAPVS 144
Query: 477 GGVMGAQNATL 509
G +GA N L
Sbjct: 145 GMSVGAANGML 155
Score = 41.5 bits (93), Expect = 0.023
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +2
Query: 482 SHGCSERYPAFMAGGRKEDFERSLPLLKVMGAKQ--FHCGQIGSGQVAKLTNNMLMGITG 655
S G + GG D ER P+ + MG + H G G+G KL N L
Sbjct: 147 SVGAANGMLQIFVGGEPADVERLRPVFEAMGDPERILHVGGHGAGYAVKLMINQLWFSHL 206
Query: 656 MATAECMNMGIKMGLE 703
+ATAE ++ G+K G++
Sbjct: 207 VATAEVLSTGVKAGVD 222
>UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6;
Trypanosomatidae|Rep: Dehydrogenase-like protein -
Leishmania major
Length = 431
Score = 41.9 bits (94), Expect = 0.018
Identities = 21/63 (33%), Positives = 31/63 (49%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG E +R P+ ++ H G GSG AKL + L+ A AE M + ++
Sbjct: 154 MVGGPAEQVQRVSPIFRMYADHIHHMGANGSGTAAKLLSQALVASHNAAAAEAMTIANRL 213
Query: 695 GLE 703
G+E
Sbjct: 214 GIE 216
Score = 38.3 bits (85), Expect = 0.22
Identities = 21/67 (31%), Positives = 37/67 (55%)
Frame = +3
Query: 309 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 488
S KV+L+ + +V +A+ G +++D +T+D + ++ A +G F DAP+SG
Sbjct: 88 SRKVLLE---DSEALVTNARPGQIIVDHTTVDMELSRECAHEAERRGAVFLDAPMSGSPK 144
Query: 489 GAQNATL 509
A N L
Sbjct: 145 QAFNNQL 151
>UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Leptosphaeria maculans|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Leptosphaeria
maculans (Blackleg fungus)
Length = 296
Score = 41.9 bits (94), Expect = 0.018
Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
Frame = +2
Query: 554 PLLKVMGA-KQFH-CGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 709
P L ++G +FH +G+G AK+ NN L G +ATAE + +G + GL+P+
Sbjct: 125 PTLHMLGPPSKFHYLSTLGAGLTAKIANNYLSGTILLATAEALALGTRHGLDPR 178
>UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Polaromonas sp. JS666|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 41.5 bits (93), Expect = 0.023
Identities = 22/65 (33%), Positives = 31/65 (47%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M G + F++ P+L FH G G+G V KL NN + ATAE +G
Sbjct: 137 MVGAEQAVFDKIRPVLAAYCENIFHVGGPGAGHVIKLLNNFIGQAICTATAEAFAVGALA 196
Query: 695 GLEPK 709
G+ P+
Sbjct: 197 GINPQ 201
Score = 40.7 bits (91), Expect = 0.041
Identities = 18/58 (31%), Positives = 34/58 (58%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
+T + V G DGV++ A G ++ID+ST +P +++ + E+G+ DAP++
Sbjct: 66 VTGSPQVEQTLSGPDGVLSRALAGLIVIDTSTSEPESTRRLAALCAERGVTLVDAPLA 123
>UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2;
Arabidopsis thaliana|Rep: Fructose-bisphosphate aldolase
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1486
Score = 41.5 bits (93), Expect = 0.023
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
+A GR + R+ P L M + G+IG+G K+ N +L GI +A E +++G +
Sbjct: 163 IASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNELLEGIHLVAAVEAISLGSQ 222
Query: 692 MGLEP 706
G+ P
Sbjct: 223 AGVHP 227
Score = 37.1 bits (82), Expect = 0.50
Identities = 17/30 (56%), Positives = 22/30 (73%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS 210
+ F+GLG MG MAA+L+K F+V GYD S
Sbjct: 348 IGFIGLGAMGFGMAAHLLKSNFSVCGYDIS 377
Score = 33.5 bits (73), Expect = 6.2
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
MA G E + + +L + K + G G+G K+ N +L G+ + AE M G +
Sbjct: 491 MASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVKMVNQLLAGVHIASAAEAMAFGAR 550
Query: 692 MGLEPK 709
+GL +
Sbjct: 551 LGLNTR 556
Score = 33.1 bits (72), Expect = 8.2
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Frame = +3
Query: 300 ILTSNKVVL-DVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG--LGFTDAP 470
I+ +N+V DV G G V G+ ++ +ST+ P Q+ +G L DAP
Sbjct: 416 IMVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQLERRLENEGKDLKLVDAP 475
Query: 471 VSGGVMGA 494
VSGGV A
Sbjct: 476 VSGGVKRA 483
>UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12;
cellular organisms|Rep: Fructose-bisphosphate aldolase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1373
Score = 41.5 bits (93), Expect = 0.023
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
+A GR + R+ P L M + G+IG+G K+ N +L GI +A E +++G +
Sbjct: 139 IASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNELLEGIHLVAAVEAISLGSQ 198
Query: 692 MGLEP 706
G+ P
Sbjct: 199 AGVHP 203
Score = 38.3 bits (85), Expect = 0.22
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDAL 222
+ F+GLG MG MAA+L+K F+V GYD K L
Sbjct: 324 IGFIGLGAMGFGMAAHLLKSNFSVCGYDVYKPTL 357
Score = 33.5 bits (73), Expect = 6.2
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
MA G E + + +L + K + G G+G K+ N +L G+ + AE M G +
Sbjct: 458 MASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVKMVNQLLAGVHIASAAEAMAFGAR 517
Query: 692 MGLEPK 709
+GL +
Sbjct: 518 LGLNTR 523
Score = 33.1 bits (72), Expect = 8.2
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Frame = +3
Query: 300 ILTSNKVVL-DVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG--LGFTDAP 470
I+ +N+V DV G G V G+ ++ +ST+ P Q+ +G L DAP
Sbjct: 383 IMVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQLERRLENEGKDLKLVDAP 442
Query: 471 VSGGVMGA 494
VSGGV A
Sbjct: 443 VSGGVKRA 450
>UniRef50_Q6KZX0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Picrophilus torridus|Rep: 2-hydroxy-3-oxopropionate
reductase - Picrophilus torridus
Length = 280
Score = 41.1 bits (92), Expect = 0.031
Identities = 20/34 (58%), Positives = 22/34 (64%)
Frame = +1
Query: 118 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDA 219
NV LGLG MG MA L+KK F V GYD +K A
Sbjct: 2 NVGVLGLGRMGSGMAYTLLKKNFNVTGYDVNKMA 35
>UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxyisobutyrate dehydrogenase
- Silicibacter pomeroyi
Length = 269
Score = 40.7 bits (91), Expect = 0.041
Identities = 21/65 (32%), Positives = 30/65 (46%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
+FM GG D + + PL MG+ G GSG AK+ NN+L T ++
Sbjct: 128 SFMLGGEPADLDAAQPLFAAMGSHFHRMGPYGSGMQAKVLNNLLAAANTAMTRLVLDWAD 187
Query: 689 KMGLE 703
GL+
Sbjct: 188 AAGLD 192
>UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 305
Score = 40.7 bits (91), Expect = 0.041
Identities = 20/61 (32%), Positives = 30/61 (49%)
Frame = +3
Query: 327 DVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNAT 506
D++L GV A + +D ST+ P+ ++ +G F APVSG V A +A
Sbjct: 84 DLFLASGGVAGAATADKVFVDMSTVSPDASAEVAAALARRGAAFLRAPVSGTVSLAASAQ 143
Query: 507 L 509
L
Sbjct: 144 L 144
>UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep:
3-hydroxyisobutyrate dehydrogenase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 301
Score = 40.7 bits (91), Expect = 0.041
Identities = 22/69 (31%), Positives = 34/69 (49%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L V V +DG++ K+ ++D STI P +G+ + D+PVSGG
Sbjct: 68 LPDGPAVQHVISAQDGLL-QGKRVKCVVDLSTIGPRAAVAASQALGARGIAYVDSPVSGG 126
Query: 483 VMGAQNATL 509
+ GA+ TL
Sbjct: 127 IGGAERGTL 135
Score = 40.3 bits (90), Expect = 0.054
Identities = 21/56 (37%), Positives = 28/56 (50%)
Frame = +2
Query: 539 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEP 706
++ P+LK G + G GQ KL NN+L T+E M MG K GL+P
Sbjct: 146 YDELAPVLKNFGRLFYMGAGPGLGQTMKLANNLLSAAAVAITSEAMAMGAKAGLDP 201
Score = 35.5 bits (78), Expect = 1.5
Identities = 18/39 (46%), Positives = 22/39 (56%)
Frame = +1
Query: 127 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
F+GLGNMGG M L+ G TV +D AL A +G
Sbjct: 9 FIGLGNMGGPMVKRLLHAGHTVLVFDRDAAALARAVADG 47
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 40.7 bits (91), Expect = 0.041
Identities = 18/55 (32%), Positives = 30/55 (54%)
Frame = +3
Query: 315 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 479
K D+ LG GV+ + G +D ST+D + ++ + + +G F +APVSG
Sbjct: 335 KAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSG 389
Score = 38.7 bits (86), Expect = 0.16
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
Frame = +1
Query: 61 STQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDA----LNA 228
S Q + A + TDK + FLGLG MG + +NL+K G TV ++ + + +
Sbjct: 250 SIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQE 309
Query: 229 AAKNGVTPA 255
A+ G TPA
Sbjct: 310 GARLGRTPA 318
>UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 605
Score = 40.7 bits (91), Expect = 0.041
Identities = 18/46 (39%), Positives = 29/46 (63%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAT 258
V ++GLG MG MAA+LV +G+ V+ +D +L A+ G P++
Sbjct: 9 VGWIGLGAMGSGMAASLVSQGYKVQAFDVYPPSLKRVAEQGAIPSS 54
Score = 34.7 bits (76), Expect = 2.7
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHA-KKGSLLIDSSTIDPNVPKQIFPIA--LEKGLGFTDAPVSGGVMG 491
V + GKDG VA K G+ +I ST+ P+ ++ L K +G D+PVSGG
Sbjct: 76 VEETLFGKDGGVAEILKNGASIIVFSTVPPSFLVEVARRLDKLGKNIGLVDSPVSGGSTR 135
Query: 492 AQNATL 509
A L
Sbjct: 136 AAQGQL 141
>UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=2; Anaeromyxobacter|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 293
Score = 40.3 bits (90), Expect = 0.054
Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +3
Query: 309 SNKVVLDVYL-GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 485
S++ LD L G DGV+ + G +L+D ST + + A +G GF PV G
Sbjct: 67 SDEKALDTVLEGPDGVLEALRDGDVLVDMSTAGVRAARSVSERAAARGAGFVACPVLGSR 126
Query: 486 MGAQNATL 509
A+ A L
Sbjct: 127 SAAEQAQL 134
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 40.3 bits (90), Expect = 0.054
Identities = 18/70 (25%), Positives = 38/70 (54%)
Frame = +3
Query: 300 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 479
+++ + V ++ G DG+++ G ++++ ST+ P + ++ G+ + DAPVSG
Sbjct: 75 MVSDDHAVASLFEGADGLLSKELHGKVIVNMSTVSPAISIKMAAACSAVGIEYLDAPVSG 134
Query: 480 GVMGAQNATL 509
V A + L
Sbjct: 135 SVKQATDGQL 144
Score = 39.5 bits (88), Expect = 0.094
Identities = 22/59 (37%), Positives = 27/59 (45%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
M GG ++ F + PLL MG H G G G AKL N L+ I AE + K
Sbjct: 147 MVGGEEQAFHAAEPLLSCMGKLVMHLGASGIGNKAKLAINTLLAIYTEGLAEIVTFSRK 205
>UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Arthrobacter sp. FB24|Rep: 2-hydroxy-3-oxopropionate
reductase - Arthrobacter sp. (strain FB24)
Length = 302
Score = 40.3 bits (90), Expect = 0.054
Identities = 22/72 (30%), Positives = 32/72 (44%)
Frame = +2
Query: 488 GCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 667
G E + M GG E ER PL + + H G+ G+G K N +++ T A A
Sbjct: 142 GAEEGRLSIMVGGPAEAVERLTPLFGLYSSTAVHFGKTGAGSTVKACNQIVVAATVNALA 201
Query: 668 ECMNMGIKMGLE 703
E M + L+
Sbjct: 202 EAMALASTAALD 213
>UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 444
Score = 39.9 bits (89), Expect = 0.071
Identities = 18/33 (54%), Positives = 25/33 (75%), Gaps = 1/33 (3%)
Frame = +1
Query: 109 TDK-NVAFLGLGNMGGFMAANLVKKGFTVRGYD 204
T+K ++ F+GLG MG MA NL+K G+ V+GYD
Sbjct: 3 TEKPSIGFVGLGLMGFGMATNLIKLGYVVKGYD 35
>UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 306
Score = 39.5 bits (88), Expect = 0.094
Identities = 19/45 (42%), Positives = 24/45 (53%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
+ F+GLG MGG + +L G V YD A+ AAA G PA
Sbjct: 9 IGFIGLGAMGGPICGHLAAAGHDVAAYDIQPAAVQAAAARGARPA 53
Score = 37.9 bits (84), Expect = 0.29
Identities = 21/60 (35%), Positives = 28/60 (46%)
Frame = +3
Query: 330 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
V G+ G A G+ + +ST+ P + + E G G D PVSGG GAQ L
Sbjct: 79 VLFGEGGAAAALPAGATVWLASTVAPAYARGLQARLREHGAGLVDGPVSGGATGAQAGAL 138
>UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Methylobacterium sp. 4-46|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Methylobacterium sp. 4-46
Length = 290
Score = 39.5 bits (88), Expect = 0.094
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L + + V LG +G++A +L+++ST+ P + A G+ + APVSG
Sbjct: 60 LPDDAALAAVALGPEGLLARMAPDGVLVETSTVSPETSAALREAAEAGGILYLAAPVSGS 119
Query: 483 VMGAQNATLP---SWPEVVKKTSKGPFLSS 563
A+ ATL S PE + ++ P L++
Sbjct: 120 TATAEAATLTLFCSGPETALERAR-PLLAT 148
>UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=2;
Aspergillus|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
clavatus
Length = 436
Score = 39.5 bits (88), Expect = 0.094
Identities = 20/48 (41%), Positives = 28/48 (58%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
+ F+GLG MG MA NLV++G+ V GYD ++ G PA+ L
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGYDVFPASVQRFQTAGGIPASSL 53
Score = 34.7 bits (76), Expect = 2.7
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMG-AKQFHC--GQIGSGQVAKLTNNMLMGITGMATAECMN 679
+ MAG +E +L+VM K+ + G IG+G K+ + +L GI + +E M
Sbjct: 139 SIMAGAPEEALNSGREILQVMSDQKKLYLVPGGIGAGSNMKMVHQVLAGIHILGASEAMG 198
Query: 680 MGIKMGLEPK 709
++GL+ K
Sbjct: 199 FAAQLGLDAK 208
>UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll2680 protein - Bradyrhizobium
japonicum
Length = 300
Score = 39.1 bits (87), Expect = 0.12
Identities = 18/51 (35%), Positives = 29/51 (56%)
Frame = +1
Query: 103 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
++ +NVAF+G+G MG M+ + K G+ V +D S N A G++ A
Sbjct: 2 TDASRNVAFIGIGKMGLPMSVLVAKAGYAVTAFDRSAARTNEARAQGISIA 52
Score = 37.1 bits (82), Expect = 0.50
Identities = 23/95 (24%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Frame = +3
Query: 204 SFQRCTERSGQERSDASNSIXXXXXXXXXXXSILTS---NKVVLDVYLGKDGVVAHAKKG 374
+F R R+ + R+ + +++TS + + LG GV+A G
Sbjct: 33 AFDRSAARTNEARAQGISIAASPDDAVSGKEAVITSLPDDTALRGALLGPAGVIAAMAPG 92
Query: 375 SLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 479
++LI++ST+ ++ A +G+ + APVSG
Sbjct: 93 AVLIETSTVSVEASTEVAASAQARGVLYLRAPVSG 127
>UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep:
Glr3759 protein - Gloeobacter violaceus
Length = 290
Score = 39.1 bits (87), Expect = 0.12
Identities = 19/64 (29%), Positives = 31/64 (48%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
F+ GG ++ P+L MG H G +G+G KL N L+G+ A E + +
Sbjct: 136 FLVGGDAGAVAKAGPILNAMGGTVHHAGPLGNGAAVKLAINALLGVQVAAMGELIALLRH 195
Query: 692 MGLE 703
G++
Sbjct: 196 CGID 199
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 39.1 bits (87), Expect = 0.12
Identities = 18/60 (30%), Positives = 29/60 (48%)
Frame = +3
Query: 330 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
+ G DGV G++ + S+T+DP + + + G + DAP+SGG A L
Sbjct: 105 ILFGADGVAQTLADGAVFLSSATMDPEIARTLAARLEATGRLYLDAPISGGAQRAAEGAL 164
Score = 36.3 bits (80), Expect = 0.88
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGMATAECMNMGIK 691
+A G F ++ P L M AK + G G G K+ N +L G+ A +E + +
Sbjct: 167 LASGSPAAFAKARPALDAMAAKLYELGDAPGQGAAFKMINQLLAGVHIAAASEAVAFAAR 226
Query: 692 MGLE 703
GL+
Sbjct: 227 QGLD 230
Score = 34.3 bits (75), Expect = 3.5
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +1
Query: 124 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
A +GLG+MG MA +L + GF V G+D + A+ A G
Sbjct: 36 AVIGLGSMGYGMAQSLKRAGFDVAGFDVNAAAVERFAAEG 75
>UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=7;
Pezizomycotina|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
fumigatus (Sartorya fumigata)
Length = 435
Score = 39.1 bits (87), Expect = 0.12
Identities = 19/48 (39%), Positives = 28/48 (58%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
+ F+GLG MG MA NLV++G+ V G+D ++ G PA+ L
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGFDVFPASVQRFQSQGGIPASSL 53
Score = 34.7 bits (76), Expect = 2.7
Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Frame = +3
Query: 300 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG---LGFTDAP 470
++ S V V G DGVV K + L ST+ + + + +G + F D P
Sbjct: 66 MVASAPQVQSVLFGDDGVVQFLPKNATLFLCSTVPASYAQSVAAELQSRGRADIRFIDCP 125
Query: 471 VSGGVMGAQNATL 509
VSGG A + TL
Sbjct: 126 VSGGAKRAADGTL 138
Score = 33.1 bits (72), Expect = 8.2
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQ---FHCGQIGSGQVAKLTNNMLMGITGMATAECMN 679
+ MAG +E +L+VM + G +G+G K+ + +L GI + +E M
Sbjct: 139 SIMAGASEEALNSGREILQVMSDQNKLYLVPGGVGAGSNMKMVHQVLAGIHILGASEAMG 198
Query: 680 MGIKMGLEPK 709
++GL+ K
Sbjct: 199 FAAQLGLDAK 208
>UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 293
Score = 39.1 bits (87), Expect = 0.12
Identities = 20/64 (31%), Positives = 34/64 (53%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
VLDVYLG +G+++ AK G + +++ST D ++ + +GF A + V A+
Sbjct: 70 VLDVYLGGNGILSGAKPGLIAVETSTTDIKTKLRVAEECRRRNVGFIVAMLGKTVPQAER 129
Query: 501 ATLP 512
P
Sbjct: 130 GETP 133
Score = 38.3 bits (85), Expect = 0.22
Identities = 19/46 (41%), Positives = 25/46 (54%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAT 258
V +GLG MGG L+ KGF + YD +D +N K G T A+
Sbjct: 3 VGLVGLGRMGGAFGRVLLSKGFNLVVYDVVRDKVNEFVKLGATGAS 48
>UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family
protein; n=16; Bacteria|Rep: 6-phosphogluconate
dehydrogenase family protein - Enterococcus faecalis
(Streptococcus faecalis)
Length = 299
Score = 38.7 bits (86), Expect = 0.16
Identities = 18/53 (33%), Positives = 33/53 (62%)
Frame = +1
Query: 118 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQPL 276
++ F+GLG MG MA N+ ++G+ + G+D +K+A A + G++ L + L
Sbjct: 2 DIGFIGLGKMGLNMALNVHEQGWPIIGFDVTKEARATAREQGLSVVDSLSELL 54
>UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=7; Desulfuromonadales|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Geobacter sulfurreducens
Length = 288
Score = 38.7 bits (86), Expect = 0.16
Identities = 22/50 (44%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT-PATP 261
+ V FLGLG +G MAANL+K + + YD A+ A G T ATP
Sbjct: 3 RKVGFLGLGTVGRHMAANLLKGNYELAVYDSDPAAVADLAALGATGAATP 52
>UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=5; Gammaproteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Marinomonas sp. MWYL1
Length = 300
Score = 38.7 bits (86), Expect = 0.16
Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
MA G E FE+ P+L AK ++ G +IG G K+ + +L G+ A AE M + +
Sbjct: 140 MASGSVEAFEKLQPVLDATAAKVYNIGEEIGLGATVKIIHQLLAGVHIAAGAEAMALAAR 199
Query: 692 MGL 700
+
Sbjct: 200 ANI 202
>UniRef50_A4ENK2 Cluster: 3-demethylubiquinone-9
3-methyltransferase; n=5; Rhodobacteraceae|Rep:
3-demethylubiquinone-9 3-methyltransferase - Roseobacter
sp. CCS2
Length = 240
Score = 38.7 bits (86), Expect = 0.16
Identities = 19/34 (55%), Positives = 24/34 (70%)
Frame = +1
Query: 130 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAA 231
L LG GGFMA L ++G TV G DP+KDA+ +A
Sbjct: 53 LDLGCAGGFMAEALDERGATVVGIDPAKDAIASA 86
>UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 38.3 bits (85), Expect = 0.22
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +2
Query: 521 GGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGL 700
GG + ER+ P+L G H G +G+GQ KL NN + E + +G +G+
Sbjct: 137 GGSEAAVERARPVLAAYGDPILHVGPLGAGQSVKLVNNTVFAAQIGLLREAVRLGGALGV 196
Query: 701 -EP 706
EP
Sbjct: 197 AEP 199
>UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
2-hydroxy-3-oxopropionate reductase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 38.3 bits (85), Expect = 0.22
Identities = 20/54 (37%), Positives = 29/54 (53%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
V +V ++G++ K ++ D STIDP+ K I LE G+ D PV GG
Sbjct: 71 VKEVSFEREGIIKSENKKLIVADMSTIDPSESKNISDKFLEFGIHKLDIPVMGG 124
Score = 33.5 bits (73), Expect = 6.2
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 249
K + +GLG +G + +L++ GF V ++ SKD A + G T
Sbjct: 2 KKIGIVGLGMLGNAVGLHLLESGFEVTVFNRSKDKTIQAKEKGAT 46
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 37.9 bits (84), Expect = 0.29
Identities = 16/47 (34%), Positives = 28/47 (59%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
++ AF+GLG++GG +A +L++ GF + +D A+ G T A
Sbjct: 3 ESYAFIGLGHLGGNLAPSLIRNGFAITVFDRDPAAVERLVTLGATAA 49
Score = 36.7 bits (81), Expect = 0.66
Identities = 21/63 (33%), Positives = 32/63 (50%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ GG +ER ++ M A+ F G IGS V K+ NML I +A E + + +
Sbjct: 137 LVGGDAALYERHRAAIEAMCARSFLMGPIGSAAVIKVITNMLAFIHLVAAGEALMLAKQG 196
Query: 695 GLE 703
GL+
Sbjct: 197 GLD 199
>UniRef50_Q9YFQ6 Cluster: L-lysine 6-dehydrogenase; n=1; Aeropyrum
pernix|Rep: L-lysine 6-dehydrogenase - Aeropyrum pernix
Length = 367
Score = 37.9 bits (84), Expect = 0.29
Identities = 19/42 (45%), Positives = 25/42 (59%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV 246
+A LGLG +G A NL +GF V G D S DA++ A G+
Sbjct: 4 IAVLGLGRVGLRAAYNLASRGFDVLGLDASNDAVSRARSLGL 45
>UniRef50_Q220G7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Rhodoferax ferrireducens
T118|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Rhodoferax ferrireducens (strain DSM 15236 /
ATCC BAA-621 / T118)
Length = 284
Score = 37.5 bits (83), Expect = 0.38
Identities = 19/45 (42%), Positives = 27/45 (60%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
+AFLG G +GG A K+G TV ++ S D ++A A+ GV A
Sbjct: 4 IAFLGTGLLGGAFAEAAAKRGDTVTAWNRSPDKVHALAQFGVMAA 48
>UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Verminephrobacter eiseniae EF01-2|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Verminephrobacter eiseniae (strain EF01-2)
Length = 293
Score = 37.5 bits (83), Expect = 0.38
Identities = 18/60 (30%), Positives = 30/60 (50%)
Frame = +2
Query: 521 GGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGL 700
GG+ + RS +L + ++Q H G +G+G AK+ NN + + AE M G+
Sbjct: 131 GGKPDAIARSQGVLDAIASRQIHFGALGAGAAAKVINNAVAHAVMVVVAEAGAMATAAGV 190
>UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Salinispora arenicola CNS205|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Salinispora arenicola CNS205
Length = 315
Score = 37.5 bits (83), Expect = 0.38
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 473
S+L + V+L D G + G+L +D ST+ P +++ ++G F DAPV
Sbjct: 63 SMLRDVEAGRSVWLDPDVGALTSLAPGTLAVDCSTVTPTFSRELAACCAQRGAEFLDAPV 122
Query: 474 SGGVMGAQNATL 509
G A TL
Sbjct: 123 LGSRPQADAGTL 134
Score = 34.3 bits (75), Expect = 3.5
Identities = 18/53 (33%), Positives = 24/53 (45%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAE 670
F+AGG R P+L+ +G H G G+G KL N L + AE
Sbjct: 136 FLAGGDLAVLHRIEPVLRQVGGAVHHMGPAGTGTQMKLLTNSLFAVQVATVAE 188
>UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 263
Score = 37.5 bits (83), Expect = 0.38
Identities = 20/62 (32%), Positives = 29/62 (46%)
Frame = +2
Query: 518 AGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 697
AGG + ER P L H G +GSGQ KL NN + AE + + ++G
Sbjct: 134 AGGDADVVERVRPALVAYAEPLLHVGPLGSGQRVKLVNNTMFAAQIGVVAEGVRLARELG 193
Query: 698 LE 703
++
Sbjct: 194 VD 195
>UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 37.5 bits (83), Expect = 0.38
Identities = 25/55 (45%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +1
Query: 103 SNTDKN-VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA-AAKNGVTPATP 261
S++DK VAF+GLG MG MA NL+K F+V G+D + L + G T TP
Sbjct: 2 SSSDKPAVAFIGLGAMGMGMATNLLKT-FSVTGFDVYEPTLEKFRSAGGNTATTP 55
>UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Cenarchaeum symbiosum
Length = 282
Score = 37.5 bits (83), Expect = 0.38
Identities = 22/69 (31%), Positives = 31/69 (44%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
+T + V G++G+ A K +L D STI+P I + G+ DAPV GG
Sbjct: 55 VTDADALEQVSFGENGIAQGAHKDLVLCDMSTINPEGAVSISKKLADAGIRMVDAPVMGG 114
Query: 483 VMGAQNATL 509
A L
Sbjct: 115 PGAAMRGEL 123
>UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to MGC107852 protein -
Strongylocentrotus purpuratus
Length = 432
Score = 37.1 bits (82), Expect = 0.50
Identities = 17/55 (30%), Positives = 30/55 (54%)
Frame = +1
Query: 109 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQP 273
T+K + F+GLG MG MA NL+K G V ++ + + + + + P+ + P
Sbjct: 360 TEKKIGFIGLGLMGTGMAMNLIKAGHKVTVWNRTSEKVRLYSPITIFPSLAMYSP 414
Score = 34.3 bits (75), Expect = 3.5
Identities = 15/28 (53%), Positives = 19/28 (67%)
Frame = +1
Query: 109 TDKNVAFLGLGNMGGFMAANLVKKGFTV 192
T+K + F+GLG MG MA NL+K G V
Sbjct: 277 TEKRIGFIGLGLMGTGMAMNLIKAGHKV 304
>UniRef50_UPI00003C03F8 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG4747-PA
- Apis mellifera
Length = 413
Score = 37.1 bits (82), Expect = 0.50
Identities = 17/65 (26%), Positives = 31/65 (47%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+A G + F+ + MG F+ G++G+ L ++ G+T AE M + +
Sbjct: 262 LAAGDRTLFDECQSCFEAMGKNSFYLGEVGNASKMNLVLQLMAGVTLAGLAESMALADRA 321
Query: 695 GLEPK 709
GL+ K
Sbjct: 322 GLQQK 326
>UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus
tauri|Rep: Oxidoreductase-like - Ostreococcus tauri
Length = 325
Score = 37.1 bits (82), Expect = 0.50
Identities = 22/63 (34%), Positives = 29/63 (46%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIK 691
F+ G + + R L VMG F G +G G KL NM+MG A AE + + K
Sbjct: 173 FLCAGDEGLYTRCTDPLDVMGKAHFFLGDVGQGAKMKLVVNMIMGSMMGAFAEGLTLADK 232
Query: 692 MGL 700
L
Sbjct: 233 SDL 235
Score = 33.1 bits (72), Expect = 8.2
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 5/57 (8%)
Frame = +3
Query: 354 VAHAKKGSL-----LIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
VAHA K L +D ST+D + I + G F +APVSG A++ L
Sbjct: 115 VAHAAKEGLSSGKGYVDVSTVDAGTSRAIAEVVRSTGAEFLEAPVSGSKKPAEDGAL 171
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 36.7 bits (81), Expect = 0.66
Identities = 22/71 (30%), Positives = 34/71 (47%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S+L+ + V DV G G++A + + I STI + +Q+ +G F APV
Sbjct: 62 SMLSDDDAVTDVTFGACGIIAGLSENGIHISMSTISTALSEQLSAAHSGRGQSFIAAPVL 121
Query: 477 GGVMGAQNATL 509
G A+ A L
Sbjct: 122 GRPDAAEKAEL 132
Score = 34.7 bits (76), Expect = 2.7
Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 4/48 (8%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSK----DALNAAAKNGVTP 252
+A +GLGNMG +A N++K G+++ Y+ +K D L+ A+ TP
Sbjct: 3 IAIVGLGNMGRPIAENIMKAGYSLTVYNRTKEKAADLLDKGAEYAETP 50
>UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 481
Score = 36.7 bits (81), Expect = 0.66
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Frame = +1
Query: 103 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYD--PSKDA-LNAAAKNGVTPATPL 264
S T ++ +GLG MG + N+ ++GF V GYD P K A L A+ + P+
Sbjct: 6 SPTSADIGIIGLGVMGANLGLNIAEQGFNVAGYDRNPEKGARLTQMAQKQLAEDAPM 62
>UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=1; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 438
Score = 36.7 bits (81), Expect = 0.66
Identities = 20/54 (37%), Positives = 29/54 (53%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
V +V G DG+ G++++ ST+ P ++I A GL DAPVSGG
Sbjct: 239 VEEVMFGPDGLAGTLNPGAVVLVHSTVAPAQIRRIAGRAATHGLRVLDAPVSGG 292
Score = 36.7 bits (81), Expect = 0.66
Identities = 18/64 (28%), Positives = 27/64 (42%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
M GG + LL + H G +G+G AKL NN + + M G +
Sbjct: 304 MIGGDADTLADVAELLSALSNHVVHLGAVGAGSYAKLINNTMFAAQIALADDAMKAGESL 363
Query: 695 GLEP 706
G++P
Sbjct: 364 GIDP 367
>UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Acidobacteria bacterium Ellin345|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidobacteria bacterium (strain Ellin345)
Length = 313
Score = 36.7 bits (81), Expect = 0.66
Identities = 20/48 (41%), Positives = 26/48 (54%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPL 264
V FLGLGNMG MAANL+ G V ++ + + GV AT +
Sbjct: 25 VGFLGLGNMGEPMAANLIAAGHQVTVWNRTAAKAEPLKERGVKVATEI 72
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 36.7 bits (81), Expect = 0.66
Identities = 20/66 (30%), Positives = 32/66 (48%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S++ + DV + GV + K GS+ + ST+DP + G+ + DAP+S
Sbjct: 65 SVVVNAAQTEDVLWSEQGVASAMKSGSVFVMCSTVDPQWSIATEARLDKLGIHYVDAPIS 124
Query: 477 GGVMGA 494
GG A
Sbjct: 125 GGAAKA 130
>UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomonas
sp. MED121|Rep: Putative dehydrogenase - Marinomonas sp.
MED121
Length = 297
Score = 36.7 bits (81), Expect = 0.66
Identities = 22/69 (31%), Positives = 39/69 (56%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L S+ V + G++G++ +A+ G+ ++ST + + +++ IA L DAPV+GG
Sbjct: 68 LPSSVQVNHIAFGEEGILENAQAGATWFETSTNELSEWEKVKAIA-PSHLSLIDAPVTGG 126
Query: 483 VMGAQNATL 509
GA TL
Sbjct: 127 AEGAAAGTL 135
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 36.3 bits (80), Expect = 0.88
Identities = 17/39 (43%), Positives = 23/39 (58%)
Frame = +1
Query: 115 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAA 231
+N+A +GLG MG MAA L + G V YD + A+ A
Sbjct: 3 RNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERA 41
>UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospira interrogans
Length = 296
Score = 36.3 bits (80), Expect = 0.88
Identities = 17/43 (39%), Positives = 23/43 (53%)
Frame = +2
Query: 512 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 640
FM G ++ D + +V G +CG IG GQ AKL NM+
Sbjct: 135 FMIGAKQVDIKDIQFFFEVCGKNAVYCGSIGGGQKAKLALNMI 177
>UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=34; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 289
Score = 36.3 bits (80), Expect = 0.88
Identities = 17/42 (40%), Positives = 26/42 (61%)
Frame = +1
Query: 118 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG 243
++ F+GLG MG +A NL+K G TVR ++ S++ A G
Sbjct: 2 DLGFIGLGEMGQAIATNLLKAGHTVRVWNRSRERAEPLAAIG 43
>UniRef50_Q2RVS2 Cluster: Prephenate dehydrogenase; n=1;
Rhodospirillum rubrum ATCC 11170|Rep: Prephenate
dehydrogenase - Rhodospirillum rubrum (strain ATCC 11170
/ NCIB 8255)
Length = 317
Score = 36.3 bits (80), Expect = 0.88
Identities = 20/59 (33%), Positives = 28/59 (47%)
Frame = +1
Query: 82 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAT 258
A RR + +GLG G F +L + F + G+DP++D A GV PAT
Sbjct: 24 AVRRPSGLAAKPTLGLIGLGAFGAFCVPHL-SRFFHILGHDPARDGAARALALGVLPAT 81
>UniRef50_Q1YFU0 Cluster: Posibble methylase involved in
ubiquinone/menaquinone biosynthesis; n=1; Aurantimonas
sp. SI85-9A1|Rep: Posibble methylase involved in
ubiquinone/menaquinone biosynthesis - Aurantimonas sp.
SI85-9A1
Length = 241
Score = 36.3 bits (80), Expect = 0.88
Identities = 20/42 (47%), Positives = 28/42 (66%)
Frame = +1
Query: 130 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 255
L +G G +A +LVK+GF V G DPS+ A+ AAA++ V A
Sbjct: 37 LDIGCGRGALARSLVKRGFAVTGIDPSEAAI-AAARDSVPEA 77
>UniRef50_A4SGI3 Cluster: NAD-dependent epimerase/dehydratase; n=7;
Chlorobiaceae|Rep: NAD-dependent epimerase/dehydratase -
Prosthecochloris vibrioformis DSM 265
Length = 275
Score = 36.3 bits (80), Expect = 0.88
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +1
Query: 112 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQPLME 282
++ V+ LG G +G +A L+KKGF V+G +++ L G+ P L P +E
Sbjct: 3 NQTVSILGCGWLGLPLAKALIKKGFIVKGSTTAEEHLEQLRTEGIEPYILNLSPELE 59
>UniRef50_A4ES45 Cluster: Methyltransferase type 11; n=1;
Roseobacter sp. SK209-2-6|Rep: Methyltransferase type 11
- Roseobacter sp. SK209-2-6
Length = 195
Score = 36.3 bits (80), Expect = 0.88
Identities = 20/51 (39%), Positives = 26/51 (50%)
Frame = +1
Query: 130 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPATPLLQPLME 282
L LG G AA L ++GFTV DP+ + + AA K GV+ L E
Sbjct: 44 LDLGCGPGIQAAELKQRGFTVEAIDPTPEFVMAAEKRGVSARIGTFDDLTE 94
>UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Dinoroseobacter shibae DFL
12|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Dinoroseobacter shibae DFL 12
Length = 289
Score = 36.3 bits (80), Expect = 0.88
Identities = 19/57 (33%), Positives = 29/57 (50%)
Frame = +3
Query: 345 DGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLPS 515
D ++ H + G + ID++T P + G F+DAPV+GG AQ+ L S
Sbjct: 79 DTLLPHTRPGQIWIDTTTSRPETSATLAHRLDAAGAVFSDAPVTGGPKQAQDGALTS 135
>UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Arthrobacter sp. FB24|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 297
Score = 36.3 bits (80), Expect = 0.88
Identities = 19/52 (36%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Frame = +3
Query: 330 VYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP--IALEKGLGFTDAPVSG 479
+Y + GV+A + G+L++D +T DP + + + AL G + DAPVSG
Sbjct: 77 LYDEEAGVLAGLRAGALIVDMTTGDPELAQDVAQRVAALGNGARYVDAPVSG 128
>UniRef50_P71825 Cluster: Uncharacterized oxidoreductase
Rv0770/MT0794; n=18; Corynebacterineae|Rep:
Uncharacterized oxidoreductase Rv0770/MT0794 -
Mycobacterium tuberculosis
Length = 295
Score = 36.3 bits (80), Expect = 0.88
Identities = 20/63 (31%), Positives = 28/63 (44%)
Frame = +3
Query: 321 VLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQN 500
V V +G+ HAK G+++ STI + +G+ DAPVSGG A
Sbjct: 76 VSSVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGGAAAAAK 135
Query: 501 ATL 509
L
Sbjct: 136 GEL 138
Score = 34.3 bits (75), Expect = 3.5
Identities = 20/65 (30%), Positives = 28/65 (43%)
Frame = +2
Query: 509 AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGI 688
A M G E F+R + H G+ G+G KL NML ++ A AE +
Sbjct: 139 AVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYAAAAEAQRLAE 198
Query: 689 KMGLE 703
GL+
Sbjct: 199 ACGLD 203
>UniRef50_A4ARS6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding:D-isomer specific 2- hydroxyacid
dehydrogenase, NAD-binding protein; n=2;
Flavobacteriales|Rep: 6-phosphogluconate dehydrogenase,
NAD-binding:D-isomer specific 2- hydroxyacid
dehydrogenase, NAD-binding protein - Flavobacteriales
bacterium HTCC2170
Length = 309
Score = 35.9 bits (79), Expect = 1.2
Identities = 15/39 (38%), Positives = 24/39 (61%)
Frame = +1
Query: 97 YSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSK 213
Y D + +GLG +G +A +L++ GFTV+G+ SK
Sbjct: 128 YQRIEDLTIGIMGLGALGKVLAKDLIRFGFTVQGWSGSK 166
>UniRef50_A3ZZH5 Cluster: Putative uncharacterized protein; n=1;
Blastopirellula marina DSM 3645|Rep: Putative
uncharacterized protein - Blastopirellula marina DSM
3645
Length = 707
Score = 35.9 bits (79), Expect = 1.2
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Frame = +2
Query: 344 RW-RCGSCEKRIASDRFEYNRSECSQTDLPYSPRERAGIHRCTCIWRSH 487
+W RCGSCE + S ++ SE +Q+ + + P G++ T W SH
Sbjct: 277 QWDRCGSCESLLRSGEHDWVLSEITQSSV-WKPNAALGLNSATRYWISH 324
>UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161;
n=2; Thermoplasma|Rep: Putative uncharacterized protein
Ta0161 - Thermoplasma acidophilum
Length = 290
Score = 35.9 bits (79), Expect = 1.2
Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Frame = +2
Query: 440 RERAG-IHRCTCIWRSHGCSERYPAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQV 616
+E+ G ++ I S ++ + GG ++ L+ + + G GSG
Sbjct: 113 KEKGGKMYDAPVIGTSIAVEKKALVVLVGGDLSGYDEVRDLISATANQVVYMGDNGSGLY 172
Query: 617 AKLTNNMLMGITGMATAECMNMGIKMGL 700
AKL NN+ +G + AE + G K G+
Sbjct: 173 AKLVNNLFLGSYMASLAEAVRFGRKNGI 200
>UniRef50_Q944B6 Cluster: Arogenate dehydrogenase 1, chloroplast
precursor; n=1; Arabidopsis thaliana|Rep: Arogenate
dehydrogenase 1, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 640
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +1
Query: 121 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVT 249
+ +G GN G F+ +VK+G TV Y S D + AAK GV+
Sbjct: 367 IGIVGFGNFGQFLGKTMVKQGHTVLAYSRS-DYTDEAAKLGVS 408
>UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Nasonia vitripennis
Length = 512
Score = 35.5 bits (78), Expect = 1.5
Identities = 17/65 (26%), Positives = 31/65 (47%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+A G ++ F+ MG F+ G++G+ L ++ G+T AE M + +
Sbjct: 361 LAAGDRQLFDDCNSCFGAMGKNTFYLGEVGNASKMNLVLQLMAGVTLAGLAESMALADRA 420
Query: 695 GLEPK 709
GL+ K
Sbjct: 421 GLQQK 425
>UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4747-PA - Tribolium castaneum
Length = 267
Score = 35.5 bits (78), Expect = 1.5
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+A G K F+ K +G F+ G +GS L NM +GI AE M + +
Sbjct: 115 LAAGDKSLFDDCQTCFKAIGKTAFYLGTVGSATKMNLCINMALGIGLAGLAESMVLAERC 174
Query: 695 GLEPK 709
GL K
Sbjct: 175 GLSCK 179
>UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Deinococcus radiodurans
Length = 310
Score = 35.5 bits (78), Expect = 1.5
Identities = 17/50 (34%), Positives = 28/50 (56%)
Frame = +3
Query: 360 HAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
H + G++ +D ++ P+ ++ G+ F DAPVSGG GA+ TL
Sbjct: 100 HLRPGTVWVDCTSGHPDAARRQRETLDALGVKFLDAPVSGGTSGAEAGTL 149
>UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Pectobacterium atrosepticum|Rep:
Putative 2-hydroxy-3-oxopropionate reductase - Erwinia
carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 297
Score = 35.5 bits (78), Expect = 1.5
Identities = 19/72 (26%), Positives = 34/72 (47%)
Frame = +3
Query: 303 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 482
L + + DV+ +D + + L ++ STI P + + + G + + PVSGG
Sbjct: 67 LKDAEAIRDVFQSEDVIHKLSLYRPLFLNISTIGPEESRWMETFFHQHGAHYVECPVSGG 126
Query: 483 VMGAQNATLPSW 518
GA+ L +W
Sbjct: 127 PEGARQGRLAAW 138
>UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodopseudomonas palustris BisB18|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodopseudomonas palustris (strain BisB18)
Length = 365
Score = 35.5 bits (78), Expect = 1.5
Identities = 24/71 (33%), Positives = 35/71 (49%)
Frame = +3
Query: 297 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 476
S L ++ V V G G+V K G++ I STI P + +++ E G G+ APV
Sbjct: 81 SSLPDDEAVTAVAAGAGGLVKIMKAGAVHISMSTISPTMSRRLAAWHGECGQGYVAAPVL 140
Query: 477 GGVMGAQNATL 509
G A+ TL
Sbjct: 141 GNPDLARARTL 151
>UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 493
Score = 35.5 bits (78), Expect = 1.5
Identities = 17/64 (26%), Positives = 30/64 (46%)
Frame = +2
Query: 515 MAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKM 694
+ GG + E + P+L + HCG +G+G V K+ N++ + A E +
Sbjct: 140 IVGGDEATVEAARPVLDDWARRVVHCGPLGAGMVTKIARNVVTYGSWRAVFEASALARAA 199
Query: 695 GLEP 706
G+ P
Sbjct: 200 GVNP 203
>UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=8; Gammaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Marinomonas sp. MWYL1
Length = 507
Score = 35.5 bits (78), Expect = 1.5
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +1
Query: 103 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYD 204
+N + N+ F+GLG MG +A NL G+ V G+D
Sbjct: 4 TNQNCNIGFVGLGVMGKNLALNLADHGYRVAGFD 37
>UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 299
Score = 35.5 bits (78), Expect = 1.5
Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +3
Query: 327 DVYLGKDGVVAHAKKGSLLIDSSTIDPN-VPKQIFPIALEKGLGFTDAPVSGG 482
DV G +GV + K G+++I ST+ + +P + +A E G+ DAP+SGG
Sbjct: 75 DVLFGANGVASVLKPGAVVILGSTVGTDAIPATVDRLA-EYGVELVDAPLSGG 126
>UniRef50_Q0U6Q6 Cluster: Putative uncharacterized protein; n=5;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 311
Score = 35.5 bits (78), Expect = 1.5
Identities = 18/55 (32%), Positives = 25/55 (45%)
Frame = +3
Query: 345 DGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATL 509
D ++ KG L++D ST+ P+ + EKG F PV G A N L
Sbjct: 88 DTILQEDTKGKLIVDCSTVHPDTTNALEKRITEKGAEFVGMPVFGAPAMADNGQL 142
>UniRef50_A1U1I8 Cluster: Erythronate-4-phosphate dehydrogenase;
n=4; Gammaproteobacteria|Rep: Erythronate-4-phosphate
dehydrogenase - Marinobacter aquaeolei (strain ATCC
700491 / DSM 11845 / VT8)(Marinobacter
hydrocarbonoclasticus (strain DSM 11845))
Length = 384
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/75 (29%), Positives = 33/75 (44%)
Frame = +1
Query: 46 ARTILSTQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALN 225
A +LS LY A +R + V +G+GN+GG +A L + FTV+ DP +
Sbjct: 96 AEYVLSVLSLY-AEKRGIEDWSSLTVGIVGVGNVGGELARMLERLDFTVKLCDPPRQEAE 154
Query: 226 AAAKNGVTPATPLLQ 270
P L+
Sbjct: 155 EERAEEFVPLAEALE 169
>UniRef50_Q5PAV2 Cluster: 3-demethylubiquinone-9
3-methyltransferase; n=1; Anaplasma marginale str. St.
Maries|Rep: 3-demethylubiquinone-9 3-methyltransferase -
Anaplasma marginale (strain St. Maries)
Length = 225
Score = 35.1 bits (77), Expect = 2.0
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +1
Query: 124 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAA 234
+ L +G GG A ++V+ GF+V G DPS+ ++ AA+
Sbjct: 38 SLLDIGCGGGIFAESMVRLGFSVTGVDPSQASIEAAS 74
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 895,712,299
Number of Sequences: 1657284
Number of extensions: 20192065
Number of successful extensions: 60708
Number of sequences better than 10.0: 288
Number of HSP's better than 10.0 without gapping: 57033
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 60633
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 67085240885
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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