Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP21_F_F02
(906 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U36308-1|AAC02794.2| 263|Homo sapiens lens major intrinsic prot... 39 0.022
BC117474-1|AAI17475.1| 263|Homo sapiens major intrinsic protein... 39 0.022
BC074913-1|AAH74913.1| 263|Homo sapiens major intrinsic protein... 39 0.022
U63623-1|AAB26958.1| 301|Homo sapiens aquaporin 4 protein. 38 0.050
U63622-1|AAB26957.1| 323|Homo sapiens aquaporin 4 protein. 38 0.050
U34846-1|AAC52112.1| 341|Homo sapiens mercurial-insensitive wat... 38 0.050
U34845-1|AAC50284.1| 301|Homo sapiens mercurial-insensitive wat... 38 0.050
D63412-1|BAA09715.1| 323|Homo sapiens aquaporin protein. 38 0.050
BC022286-1|AAH22286.1| 323|Homo sapiens aquaporin 4 protein. 38 0.050
AK222684-1|BAD96404.1| 323|Homo sapiens aquaporin 4 isoform a v... 38 0.050
AB128929-1|BAD22823.1| 218|Homo sapiens aquaporin type4 transcr... 38 0.050
AF000143-1|AAC03168.1| 263|Homo sapiens putative alternative le... 36 0.20
BC040630-1|AAH40630.1| 255|Homo sapiens AQP8 protein protein. 36 0.27
AK222975-1|BAD96695.1| 261|Homo sapiens aquaporin 8 variant pro... 36 0.27
AK222964-1|BAD96684.1| 261|Homo sapiens aquaporin 8 variant pro... 36 0.27
AF067797-1|AAF19050.1| 261|Homo sapiens aquaporin 8 protein. 36 0.27
AB013456-1|BAA34223.1| 261|Homo sapiens aquaporin 8 protein. 36 0.27
U48408-1|AAB41566.1| 282|Homo sapiens water channel protein. 34 0.62
Z29491-1|CAA82627.1| 271|Homo sapiens water channel aquaporin-2... 32 3.3
S73197-1|AAB31998.1| 271|Homo sapiens water-channel aquaporin 2... 32 3.3
S73196-1|AAB31999.1| 271|Homo sapiens water-channel aquaporin 2... 32 3.3
D31846-1|BAA06632.1| 271|Homo sapiens human aquaporin-2 water c... 32 3.3
CR542024-1|CAG46821.1| 271|Homo sapiens AQP2 protein. 32 3.3
BC042496-1|AAH42496.1| 271|Homo sapiens aquaporin 2 (collecting... 32 3.3
AF147093-1|AAD38692.1| 271|Homo sapiens aquaporin 2 protein. 32 3.3
>U36308-1|AAC02794.2| 263|Homo sapiens lens major intrinsic protein
protein.
Length = 263
Score = 39.1 bits (87), Expect = 0.022
Identities = 19/52 (36%), Positives = 23/52 (44%)
Frame = -3
Query: 442 GGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLAXXXPXXLLXPR 287
G TG +NP F P + G + N W GP+ G GL LL PR
Sbjct: 175 GMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPR 226
>BC117474-1|AAI17475.1| 263|Homo sapiens major intrinsic protein of
lens fiber protein.
Length = 263
Score = 39.1 bits (87), Expect = 0.022
Identities = 19/52 (36%), Positives = 23/52 (44%)
Frame = -3
Query: 442 GGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLAXXXPXXLLXPR 287
G TG +NP F P + G + N W GP+ G GL LL PR
Sbjct: 175 GMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPR 226
>BC074913-1|AAH74913.1| 263|Homo sapiens major intrinsic protein of
lens fiber protein.
Length = 263
Score = 39.1 bits (87), Expect = 0.022
Identities = 19/52 (36%), Positives = 23/52 (44%)
Frame = -3
Query: 442 GGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLAXXXPXXLLXPR 287
G TG +NP F P + G + N W GP+ G GL LL PR
Sbjct: 175 GMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPR 226
>U63623-1|AAB26958.1| 301|Homo sapiens aquaporin 4 protein.
Length = 301
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = -3
Query: 430 TGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLA 320
TG S+NP F P + G W N W GP+ G LA
Sbjct: 186 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLA 222
>U63622-1|AAB26957.1| 323|Homo sapiens aquaporin 4 protein.
Length = 323
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = -3
Query: 430 TGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLA 320
TG S+NP F P + G W N W GP+ G LA
Sbjct: 208 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLA 244
>U34846-1|AAC52112.1| 341|Homo sapiens mercurial-insensitive water
channel protein.
Length = 341
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = -3
Query: 430 TGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLA 320
TG S+NP F P + G W N W GP+ G LA
Sbjct: 226 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLA 262
>U34845-1|AAC50284.1| 301|Homo sapiens mercurial-insensitive water
channel protein.
Length = 301
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = -3
Query: 430 TGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLA 320
TG S+NP F P + G W N W GP+ G LA
Sbjct: 186 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLA 222
>D63412-1|BAA09715.1| 323|Homo sapiens aquaporin protein.
Length = 323
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = -3
Query: 430 TGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLA 320
TG S+NP F P + G W N W GP+ G LA
Sbjct: 208 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLA 244
>BC022286-1|AAH22286.1| 323|Homo sapiens aquaporin 4 protein.
Length = 323
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = -3
Query: 430 TGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLA 320
TG S+NP F P + G W N W GP+ G LA
Sbjct: 208 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLA 244
>AK222684-1|BAD96404.1| 323|Homo sapiens aquaporin 4 isoform a
variant protein.
Length = 323
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = -3
Query: 430 TGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLA 320
TG S+NP F P + G W N W GP+ G LA
Sbjct: 208 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLA 244
>AB128929-1|BAD22823.1| 218|Homo sapiens aquaporin type4 transcript
variant c protein.
Length = 218
Score = 37.9 bits (84), Expect = 0.050
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = -3
Query: 430 TGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLA 320
TG S+NP F P + G W N W GP+ G LA
Sbjct: 103 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLA 139
>AF000143-1|AAC03168.1| 263|Homo sapiens putative alternative lens
membrane intrinsic protein protein.
Length = 263
Score = 35.9 bits (79), Expect = 0.20
Identities = 18/52 (34%), Positives = 22/52 (42%)
Frame = -3
Query: 442 GGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLAXXXPXXLLXPR 287
G TG +NP F P + + N W GP+ G GL LL PR
Sbjct: 175 GMYYTGAGMNPARSFAPAILTRNFSNHWVYWVGPIIGGGLGSLLYDFLLFPR 226
>BC040630-1|AAH40630.1| 255|Homo sapiens AQP8 protein protein.
Length = 255
Score = 35.5 bits (78), Expect = 0.27
Identities = 15/52 (28%), Positives = 19/52 (36%)
Frame = -3
Query: 493 PXXPXKXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPL 338
P P G + GG +G +NP F P + W W GPL
Sbjct: 178 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPL 229
>AK222975-1|BAD96695.1| 261|Homo sapiens aquaporin 8 variant
protein.
Length = 261
Score = 35.5 bits (78), Expect = 0.27
Identities = 15/52 (28%), Positives = 19/52 (36%)
Frame = -3
Query: 493 PXXPXKXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPL 338
P P G + GG +G +NP F P + W W GPL
Sbjct: 184 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPL 235
>AK222964-1|BAD96684.1| 261|Homo sapiens aquaporin 8 variant
protein.
Length = 261
Score = 35.5 bits (78), Expect = 0.27
Identities = 15/52 (28%), Positives = 19/52 (36%)
Frame = -3
Query: 493 PXXPXKXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPL 338
P P G + GG +G +NP F P + W W GPL
Sbjct: 184 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPL 235
>AF067797-1|AAF19050.1| 261|Homo sapiens aquaporin 8 protein.
Length = 261
Score = 35.5 bits (78), Expect = 0.27
Identities = 15/52 (28%), Positives = 19/52 (36%)
Frame = -3
Query: 493 PXXPXKXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPL 338
P P G + GG +G +NP F P + W W GPL
Sbjct: 184 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPL 235
>AB013456-1|BAA34223.1| 261|Homo sapiens aquaporin 8 protein.
Length = 261
Score = 35.5 bits (78), Expect = 0.27
Identities = 15/52 (28%), Positives = 19/52 (36%)
Frame = -3
Query: 493 PXXPXKXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPL 338
P P G + GG +G +NP F P + W W GPL
Sbjct: 184 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPL 235
>U48408-1|AAB41566.1| 282|Homo sapiens water channel protein.
Length = 282
Score = 34.3 bits (75), Expect = 0.62
Identities = 21/61 (34%), Positives = 25/61 (40%)
Frame = -3
Query: 472 GIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPGLAXXXPXXLLX 293
GI A G TG S+NP F P + G + W GPL G LA +L
Sbjct: 177 GISWALGHLIGILFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLF 236
Query: 292 P 290
P
Sbjct: 237 P 237
>Z29491-1|CAA82627.1| 271|Homo sapiens water channel aquaporin-2
protein.
Length = 271
Score = 31.9 bits (69), Expect = 3.3
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Frame = -3
Query: 502 GXXPXXPX-KXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPG 326
G P P G A G TG S+NP P + G + + W GPL G
Sbjct: 154 GENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAI 213
Query: 325 LAXXXPXXLLXPRA 284
L +L P A
Sbjct: 214 LGSLLYNYVLFPPA 227
>S73197-1|AAB31998.1| 271|Homo sapiens water-channel aquaporin 2
protein.
Length = 271
Score = 31.9 bits (69), Expect = 3.3
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Frame = -3
Query: 502 GXXPXXPX-KXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPG 326
G P P G A G TG S+NP P + G + + W GPL G
Sbjct: 154 GENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAI 213
Query: 325 LAXXXPXXLLXPRA 284
L +L P A
Sbjct: 214 LGSLLYNYVLFPPA 227
>S73196-1|AAB31999.1| 271|Homo sapiens water-channel aquaporin 2
protein.
Length = 271
Score = 31.9 bits (69), Expect = 3.3
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Frame = -3
Query: 502 GXXPXXPX-KXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPG 326
G P P G A G TG S+NP P + G + + W GPL G
Sbjct: 154 GENPGTPALSIGFSVALGHLLGIHYTGCSMNPACSLAPAVVTGKFDDHWVFWIGPLVGAI 213
Query: 325 LAXXXPXXLLXPRA 284
L +L P A
Sbjct: 214 LGSLLYNYVLFPPA 227
>D31846-1|BAA06632.1| 271|Homo sapiens human aquaporin-2 water
channel protein.
Length = 271
Score = 31.9 bits (69), Expect = 3.3
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Frame = -3
Query: 502 GXXPXXPX-KXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPG 326
G P P G A G TG S+NP P + G + + W GPL G
Sbjct: 154 GENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAI 213
Query: 325 LAXXXPXXLLXPRA 284
L +L P A
Sbjct: 214 LGSLLYNYVLFPPA 227
>CR542024-1|CAG46821.1| 271|Homo sapiens AQP2 protein.
Length = 271
Score = 31.9 bits (69), Expect = 3.3
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Frame = -3
Query: 502 GXXPXXPX-KXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPG 326
G P P G A G TG S+NP P + G + + W GPL G
Sbjct: 154 GENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAI 213
Query: 325 LAXXXPXXLLXPRA 284
L +L P A
Sbjct: 214 LGSLLYNYVLFPPA 227
>BC042496-1|AAH42496.1| 271|Homo sapiens aquaporin 2 (collecting
duct) protein.
Length = 271
Score = 31.9 bits (69), Expect = 3.3
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Frame = -3
Query: 502 GXXPXXPX-KXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPG 326
G P P G A G TG S+NP P + G + + W GPL G
Sbjct: 154 GENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAI 213
Query: 325 LAXXXPXXLLXPRA 284
L +L P A
Sbjct: 214 LGSLLYNYVLFPPA 227
>AF147093-1|AAD38692.1| 271|Homo sapiens aquaporin 2 protein.
Length = 271
Score = 31.9 bits (69), Expect = 3.3
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Frame = -3
Query: 502 GXXPXXPX-KXGIXXAXVVFXGGXXTGXSLNPXXXFXPXLXXGXWXNXWXXXXGPLGGPG 326
G P P G A G TG S+NP P + G + + W GPL G
Sbjct: 154 GENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAI 213
Query: 325 LAXXXPXXLLXPRA 284
L +L P A
Sbjct: 214 LGSLLYNYVLFPPA 227
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 70,155,579
Number of Sequences: 237096
Number of extensions: 947415
Number of successful extensions: 2553
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 1959
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2523
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11714809042
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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