Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0005_I08
(375 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B59A5 Cluster: PREDICTED: similar to ENSANGP000... 194 3e-49
UniRef50_P11586 Cluster: C-1-tetrahydrofolate synthase, cytoplas... 184 5e-46
UniRef50_Q4S6Y9 Cluster: Chromosome 14 SCAF14723, whole genome s... 169 1e-41
UniRef50_A7P012 Cluster: Chromosome chr6 scaffold_3, whole genom... 167 8e-41
UniRef50_Q9SPK5 Cluster: Formate--tetrahydrofolate ligase; n=105... 164 5e-40
UniRef50_Q87HX2 Cluster: Formate--tetrahydrofolate ligase; n=65;... 143 1e-33
UniRef50_Q6ABS5 Cluster: Formate--tetrahydrofolate ligase; n=52;... 134 4e-31
UniRef50_Q81RE1 Cluster: Formate--tetrahydrofolate ligase; n=48;... 128 2e-29
UniRef50_Q8Y624 Cluster: Formate--tetrahydrofolate ligase; n=71;... 123 1e-27
UniRef50_A1SQH3 Cluster: Formate--tetrahydrofolate ligase; n=38;... 121 4e-27
UniRef50_Q5FJY2 Cluster: Formate--tetrahydrofolate ligase 1; n=5... 118 5e-26
UniRef50_Q5V5Y2 Cluster: Formate--tetrahydrofolate ligase; n=406... 115 2e-25
UniRef50_A5WI04 Cluster: Formate--tetrahydrofolate ligase; n=5; ... 112 2e-24
UniRef50_Q1DFW5 Cluster: Formate--tetrahydrofolate ligase; n=2; ... 112 2e-24
UniRef50_Q3ZX40 Cluster: Formate--tetrahydrofolate ligase; n=12;... 111 4e-24
UniRef50_A6CAY4 Cluster: Formate--tetrahydrofolate ligase; n=3; ... 107 5e-23
UniRef50_A3EUA4 Cluster: Formyltetrahydrofolate synthetase; n=2;... 100 1e-20
UniRef50_Q9PQS1 Cluster: Formate--tetrahydrofolate ligase; n=1; ... 99 1e-20
UniRef50_Q97CL3 Cluster: Formate--tetrahydrofolate ligase; n=4; ... 97 9e-20
UniRef50_Q14NV0 Cluster: Probable formate-tetrahydrofolate ligas... 81 5e-15
UniRef50_Q8EUQ1 Cluster: Formate--tetrahydrofolate ligase; n=1; ... 81 6e-15
UniRef50_Q8G700 Cluster: Formate--tetrahydrofolate ligase; n=4; ... 52 3e-06
UniRef50_Q00SR1 Cluster: 10-formyltetra; n=1; Ostreococcus tauri... 42 0.003
UniRef50_Q8GJ02 Cluster: Formyltetrahydrofolate synthetase; n=12... 36 0.18
UniRef50_Q0ZQ16 Cluster: Formyl tetrahydrofolate synthetase; n=1... 35 0.56
UniRef50_Q8L054 Cluster: Putative formyltetrahydrofolate synthet... 35 0.56
UniRef50_Q6PPA4 Cluster: P-glycoprotein D; n=1; Leishmania taren... 34 0.98
UniRef50_Q4Q6D6 Cluster: P-glycoprotein e; n=7; Trypanosomatidae... 34 0.98
UniRef50_Q4Q6D4 Cluster: Multidrug resistance protein, copy 1-li... 34 0.98
UniRef50_Q5CN90 Cluster: Last step in pyrimidine biosynthesis pa... 33 1.3
UniRef50_Q9F3L3 Cluster: Acetyltransferase; n=3; Streptomyces|Re... 33 1.7
UniRef50_UPI0000F2CC46 Cluster: PREDICTED: hypothetical protein;... 32 3.9
UniRef50_A4FCM1 Cluster: Putative uncharacterized protein; n=1; ... 32 3.9
UniRef50_Q4K885 Cluster: Ais protein, putative; n=1; Pseudomonas... 31 5.2
UniRef50_A4S262 Cluster: Predicted protein; n=2; Ostreococcus|Re... 31 5.2
UniRef50_A7RJ10 Cluster: Predicted protein; n=1; Nematostella ve... 31 5.2
UniRef50_Q8YVT6 Cluster: All1888 protein; n=6; Nostocaceae|Rep: ... 31 6.9
UniRef50_Q5GZX9 Cluster: Putative uncharacterized protein; n=12;... 31 6.9
UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, wh... 31 6.9
UniRef50_Q48HY4 Cluster: Putative uncharacterized protein; n=1; ... 31 9.1
UniRef50_Q0WYD4 Cluster: Phytochromobilin synthase; n=1; Physcom... 31 9.1
UniRef50_A2QEI5 Cluster: Putative uncharacterized protein; n=1; ... 31 9.1
UniRef50_Q7Z5H4 Cluster: Vomeronasal type-1 receptor 5; n=3; Hom... 31 9.1
>UniRef50_UPI00015B59A5 Cluster: PREDICTED: similar to
ENSANGP00000016878; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000016878 - Nasonia
vitripennis
Length = 866
Score = 194 bits (474), Expect = 3e-49
Identities = 91/124 (73%), Positives = 106/124 (85%)
Frame = +2
Query: 2 PNEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARR 181
PNE+S YG KAKI LSVI RL++++ GKY+VVAGITPTPLGEGKSTT +GLVQAL A +
Sbjct: 344 PNELSPYGSKKAKIGLSVIKRLQHQKDGKYVVVAGITPTPLGEGKSTTSLGLVQALTAHK 403
Query: 182 GRNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMD 361
G+N+FA +RQPSQGPTFGVK Y+QVIPMEEFNLH+TGDIHAVTAANNL+AAQ+D
Sbjct: 404 GKNSFATLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAVTAANNLMAAQID 463
Query: 362 ARIF 373
AR F
Sbjct: 464 ARYF 467
>UniRef50_P11586 Cluster: C-1-tetrahydrofolate synthase, cytoplasmic
(C1-THF synthase) [Includes: Methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
synthetase (EC 6.3.4.3)]; n=86; cellular organisms|Rep:
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF
synthase) [Includes: Methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
synthetase (EC 6.3.4.3)] - Homo sapiens (Human)
Length = 935
Score = 184 bits (448), Expect = 5e-46
Identities = 86/122 (70%), Positives = 100/122 (81%)
Frame = +2
Query: 8 EVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGR 187
EV YG TKAK+ LS ++RL+++ GKY+VV GITPTPLGEGKSTT IGLVQAL A +
Sbjct: 344 EVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQ 403
Query: 188 NAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMDAR 367
N FAC+RQPSQGPTFG+K YSQVIPMEEFNLH+TGDIHA+TAANNL+AA +DAR
Sbjct: 404 NVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDAR 463
Query: 368 IF 373
IF
Sbjct: 464 IF 465
>UniRef50_Q4S6Y9 Cluster: Chromosome 14 SCAF14723, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 14 SCAF14723, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1066
Score = 169 bits (411), Expect = 1e-41
Identities = 83/129 (64%), Positives = 99/129 (76%), Gaps = 6/129 (4%)
Frame = +2
Query: 2 PNEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARR 181
P E+ YGR+KAK+ LS++DRL N+ GKY++VAGITPTPLGEGKST IGLVQAL A
Sbjct: 302 PEELEVYGRSKAKVRLSLLDRLHNQPDGKYVLVAGITPTPLGEGKSTVTIGLVQALSAHL 361
Query: 182 GRNAFACMRQPSQGPTFGVK------XXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNL 343
N+FAC+RQPSQGPTF + Y+QVIPMEEFNLH+TGDIHA+TAANNL
Sbjct: 362 KLNSFACLRQPSQGPTFWGESNLLCLGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNL 421
Query: 344 LAAQMDARI 370
+AA +DARI
Sbjct: 422 VAAAIDARI 430
>UniRef50_A7P012 Cluster: Chromosome chr6 scaffold_3, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr6 scaffold_3, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 594
Score = 167 bits (405), Expect = 8e-41
Identities = 78/124 (62%), Positives = 92/124 (74%)
Frame = +2
Query: 2 PNEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARR 181
P+ YG+ KAK+ LSV+D L+ G Y+VV GITPTPLGEGKSTT +GL QAL A
Sbjct: 43 PSHYDLYGKYKAKVLLSVLDDLQGSGDGYYVVVGGITPTPLGEGKSTTTVGLCQALGAFL 102
Query: 182 GRNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMD 361
+ C+RQPSQGPTFG+K YSQVIPM+EFNLH+TGDIHA+TAANNLLAA +D
Sbjct: 103 DKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITAANNLLAAAID 162
Query: 362 ARIF 373
RIF
Sbjct: 163 TRIF 166
>UniRef50_Q9SPK5 Cluster: Formate--tetrahydrofolate ligase; n=105;
root|Rep: Formate--tetrahydrofolate ligase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 634
Score = 164 bits (398), Expect = 5e-40
Identities = 76/124 (61%), Positives = 90/124 (72%)
Frame = +2
Query: 2 PNEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARR 181
P YG+ KAK+ LS D L+ + G Y+VV GITPTPLGEGKSTT +GL QAL A
Sbjct: 40 PLHYDLYGKYKAKVLLSAFDELQGQEDGYYVVVGGITPTPLGEGKSTTTVGLCQALGAYL 99
Query: 182 GRNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMD 361
+ C+RQPSQGPTFG+K YSQVIPM+EFNLH+TGDIHA+TA+NNLLAA +D
Sbjct: 100 DKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITASNNLLAAAID 159
Query: 362 ARIF 373
RIF
Sbjct: 160 TRIF 163
>UniRef50_Q87HX2 Cluster: Formate--tetrahydrofolate ligase; n=65;
Bacteria|Rep: Formate--tetrahydrofolate ligase - Vibrio
parahaemolyticus
Length = 582
Score = 143 bits (346), Expect = 1e-33
Identities = 67/124 (54%), Positives = 87/124 (70%)
Frame = +2
Query: 2 PNEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARR 181
P E +G+ KAK+ + RL + ++GK ++V ITPTPLGEGK+ T IGL Q L A+
Sbjct: 27 PEEFDTHGKYKAKVHPKCLARLNDNQNGKLVLVTAITPTPLGEGKTVTTIGLAQGL-AKL 85
Query: 182 GRNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMD 361
++ AC+RQPS GP FG+K YSQV PMEE NLH+TGDIHAVTAA+NL +A +D
Sbjct: 86 KQSVMACIRQPSMGPVFGIKGGAAGGGYSQVAPMEELNLHLTGDIHAVTAAHNLASAALD 145
Query: 362 ARIF 373
AR+F
Sbjct: 146 ARLF 149
>UniRef50_Q6ABS5 Cluster: Formate--tetrahydrofolate ligase; n=52;
root|Rep: Formate--tetrahydrofolate ligase -
Propionibacterium acnes
Length = 563
Score = 134 bits (325), Expect = 4e-31
Identities = 62/114 (54%), Positives = 81/114 (71%)
Frame = +2
Query: 20 YGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAFA 199
YGR AK+ L V+ R+ GKY+VV +TPTPLGEGK+TT +GL Q L + G+++
Sbjct: 33 YGRGVAKVDLDVVTHNRDHSCGKYVVVTAMTPTPLGEGKTTTAVGLAQGL-EKIGKHSVL 91
Query: 200 CMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMD 361
+RQPS GPTFG+K YSQV+PME+ NLH+TGD HA+ AA+NLLAA +D
Sbjct: 92 ALRQPSMGPTFGIKGGAAGAGYSQVLPMEKLNLHLTGDFHAIGAAHNLLAAMID 145
>UniRef50_Q81RE1 Cluster: Formate--tetrahydrofolate ligase; n=48;
root|Rep: Formate--tetrahydrofolate ligase - Bacillus
anthracis
Length = 562
Score = 128 bits (310), Expect = 2e-29
Identities = 60/122 (49%), Positives = 80/122 (65%)
Frame = +2
Query: 5 NEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRG 184
+E+ YG K K+SL + RL+N++ GK ++V I PTP GEGKST +GL QA + G
Sbjct: 34 DELEPYGHYKGKLSLDIFKRLQNEKDGKVVLVTAINPTPAGEGKSTVTVGLGQAF-NKIG 92
Query: 185 RNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMDA 364
+ +R+PS GPT G+K +SQV+PME+ NLH TGDIHA+T ANN LAA +D
Sbjct: 93 KKTVIALREPSLGPTMGLKGGAAGGGFSQVVPMEDINLHFTGDIHAITTANNALAAFIDN 152
Query: 365 RI 370
I
Sbjct: 153 HI 154
>UniRef50_Q8Y624 Cluster: Formate--tetrahydrofolate ligase; n=71;
Bacteria|Rep: Formate--tetrahydrofolate ligase -
Listeria monocytogenes
Length = 560
Score = 123 bits (296), Expect = 1e-27
Identities = 57/114 (50%), Positives = 76/114 (66%)
Frame = +2
Query: 20 YGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAFA 199
YG+ KAK+S I L++K GK ++V I PTP GEGKST +GL AL +++ +
Sbjct: 37 YGKYKAKLSYDTIHSLKDKEPGKLVLVTAINPTPAGEGKSTVTVGLGDAL-SKKDKKTVI 95
Query: 200 CMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMD 361
+R+PS GPT G+K Y+QVIPME+ NLH TGD HA+TAANN L+A +D
Sbjct: 96 ALREPSLGPTMGIKGGATGGGYAQVIPMEDINLHFTGDFHAITAANNALSAFID 149
>UniRef50_A1SQH3 Cluster: Formate--tetrahydrofolate ligase; n=38;
cellular organisms|Rep: Formate--tetrahydrofolate ligase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 559
Score = 121 bits (292), Expect = 4e-27
Identities = 56/117 (47%), Positives = 78/117 (66%)
Frame = +2
Query: 20 YGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAFA 199
YG KAK+ ++ ++ L ++ G+ I+V ++PTP GEGK+TT +GL AL G+ A A
Sbjct: 34 YGHYKAKVGITYLNSLADRPLGRLILVTALSPTPPGEGKTTTSVGLTDALHGL-GKRAIA 92
Query: 200 CMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMDARI 370
C+R+PS GP FG+K YSQV+PM + NLH TGD A+ AANNLLAA +D +
Sbjct: 93 CLREPSMGPVFGLKGGAAGGGYSQVVPMTDINLHFTGDFAAIAAANNLLAALIDNHV 149
>UniRef50_Q5FJY2 Cluster: Formate--tetrahydrofolate ligase 1; n=56;
Bacteria|Rep: Formate--tetrahydrofolate ligase 1 -
Lactobacillus acidophilus
Length = 558
Score = 118 bits (283), Expect = 5e-26
Identities = 58/123 (47%), Positives = 81/123 (65%), Gaps = 1/123 (0%)
Frame = +2
Query: 8 EVSQYGRTKAKISLSVIDRLR-NKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRG 184
++ YG+ KAKI+ I+R+R N + GK I+V I+PTP GEGKST IGL A+ +
Sbjct: 29 DLEPYGQDKAKINWKAINRIRKNDKLGKLILVTSISPTPAGEGKSTITIGLGDAIHNQLH 88
Query: 185 RNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMDA 364
+N +R+PS GP FG+K +Q+IPME+ NLH TGD+HA+TAA + LAA +D
Sbjct: 89 KNTLIALREPSMGPVFGLKGGATGGGRAQIIPMEDINLHFTGDMHALTAAIDTLAALVDN 148
Query: 365 RIF 373
I+
Sbjct: 149 YIY 151
>UniRef50_Q5V5Y2 Cluster: Formate--tetrahydrofolate ligase; n=406;
root|Rep: Formate--tetrahydrofolate ligase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 553
Score = 115 bits (277), Expect = 2e-25
Identities = 57/125 (45%), Positives = 80/125 (64%), Gaps = 3/125 (2%)
Frame = +2
Query: 5 NEVSQYGRTKAKISLSVIDRLRNK---RSGKYIVVAGITPTPLGEGKSTTLIGLVQALCA 175
+++ +G AK+ I+RLR + R ++V G+TPTP GEGK+ T +GL Q L
Sbjct: 16 DDLQYFGEYTAKVKQHAIERLREQAENREQNLVLVTGMTPTPKGEGKTVTTVGLGQTL-N 74
Query: 176 RRGRNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQ 355
G A +R+PS GP FGVK SQV+PME+ NLH TGD+HA+T+A+NL+AA
Sbjct: 75 HVGEEAMIAIREPSLGPVFGVKGGAAGGGRSQVLPMEDINLHFTGDLHALTSAHNLIAAM 134
Query: 356 MDARI 370
+DA+I
Sbjct: 135 LDAKI 139
>UniRef50_A5WI04 Cluster: Formate--tetrahydrofolate ligase; n=5;
root|Rep: Formate--tetrahydrofolate ligase -
Psychrobacter sp. PRwf-1
Length = 569
Score = 112 bits (270), Expect = 2e-24
Identities = 57/129 (44%), Positives = 78/129 (60%), Gaps = 6/129 (4%)
Frame = +2
Query: 5 NEVSQYGRTKAKISLS-VIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCA-- 175
+++ YG KAKI+ + V D + K ++V I PTP GEGK+T IGL AL
Sbjct: 30 DKIEPYGYYKAKINPNDVFDMPAKSSNSKLVLVTAINPTPAGEGKTTVTIGLADALNRVH 89
Query: 176 ---RRGRNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLL 346
+ G+ +R+PS GP FG+K Y+QV+PME+ NLH TGD+HA+ AANNLL
Sbjct: 90 HQDQNGKRTVVALREPSVGPVFGIKGGAAGGGYAQVLPMEDINLHFTGDLHAIGAANNLL 149
Query: 347 AAQMDARIF 373
AA +D I+
Sbjct: 150 AALIDNHIY 158
>UniRef50_Q1DFW5 Cluster: Formate--tetrahydrofolate ligase; n=2;
Bacteria|Rep: Formate--tetrahydrofolate ligase -
Myxococcus xanthus (strain DK 1622)
Length = 551
Score = 112 bits (270), Expect = 2e-24
Identities = 54/124 (43%), Positives = 78/124 (62%)
Frame = +2
Query: 2 PNEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARR 181
P +V +G +AK+SL + + R R G+ ++V+ I PTP GEGK+T + L L +R
Sbjct: 17 PEDVLPWGTHRAKVSLDALGK-RGGRQGRLVLVSAINPTPPGEGKTTMSVALAMGL-RKR 74
Query: 182 GRNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMD 361
GR A A +R+PS GP FGVK + + P + NLH TGD+HA+T+ANNLL+A +D
Sbjct: 75 GRRAVAALREPSLGPVFGVKGGGTGGGQASLEPAADINLHFTGDLHAITSANNLLSALVD 134
Query: 362 ARIF 373
+F
Sbjct: 135 NAVF 138
>UniRef50_Q3ZX40 Cluster: Formate--tetrahydrofolate ligase; n=12;
cellular organisms|Rep: Formate--tetrahydrofolate ligase
- Dehalococcoides sp. (strain CBDB1)
Length = 597
Score = 111 bits (267), Expect = 4e-24
Identities = 56/123 (45%), Positives = 80/123 (65%), Gaps = 1/123 (0%)
Frame = +2
Query: 5 NEVSQYGRTKAKISLS-VIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARR 181
+E+ +G+ AK+ + V+ RL+++ +GKYI V ITPTPLGEGKSTT +GLVQ L +
Sbjct: 46 DEIIPHGKYIAKVDFAGVLARLKDRPNGKYIDVTAITPTPLGEGKSTTTMGLVQGL-GKL 104
Query: 182 GRNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMD 361
G+ +RQPS GPTF +K SQ +P+ F+L +TGDI AVT ++NL +
Sbjct: 105 GKKVTGAIRQPSSGPTFNIKGSAAGGGLSQCLPLSPFSLGLTGDIDAVTNSHNLAMVALQ 164
Query: 362 ARI 370
AR+
Sbjct: 165 ARL 167
>UniRef50_A6CAY4 Cluster: Formate--tetrahydrofolate ligase; n=3;
root|Rep: Formate--tetrahydrofolate ligase -
Planctomyces maris DSM 8797
Length = 565
Score = 107 bits (258), Expect = 5e-23
Identities = 53/123 (43%), Positives = 72/123 (58%)
Frame = +2
Query: 2 PNEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARR 181
P + YGR KAK+ + D+ ++ KYI V I PTPLGEGK+ T+IGL AL ++
Sbjct: 28 PGDYEPYGRLKAKLVHGLADKYADRPLAKYIGVTAINPTPLGEGKTVTVIGLAMAL-SQL 86
Query: 182 GRNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMD 361
G +R+PS P FG+K + P + NLH TGD+HAVT+A NLLA+ +D
Sbjct: 87 GHTTIGTLREPSLAPVFGIKGGGAGGGNCTLEPQSDINLHFTGDLHAVTSATNLLASIID 146
Query: 362 ARI 370
I
Sbjct: 147 NHI 149
>UniRef50_A3EUA4 Cluster: Formyltetrahydrofolate synthetase; n=2;
Bacteria|Rep: Formyltetrahydrofolate synthetase -
Leptospirillum sp. Group II UBA
Length = 557
Score = 100 bits (239), Expect = 1e-20
Identities = 49/94 (52%), Positives = 62/94 (65%)
Frame = +2
Query: 89 YIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAFACMRQPSQGPTFGVKXXXXXXXYS 268
Y++V G+TPTPLGEGK+TT IGL AL R G +RQPS GP FG+K S
Sbjct: 48 YVLVTGMTPTPLGEGKTTTSIGLSMAL-NRLGTRTVVTIRQPSMGPVFGIKGGGAGGGKS 106
Query: 269 QVIPMEEFNLHMTGDIHAVTAANNLLAAQMDARI 370
+ P + NLH+TGD+HAV AA+NLLA+ +D I
Sbjct: 107 TIEPSDVLNLHLTGDVHAVGAAHNLLASAIDNEI 140
>UniRef50_Q9PQS1 Cluster: Formate--tetrahydrofolate ligase; n=1;
Ureaplasma parvum|Rep: Formate--tetrahydrofolate ligase
- Ureaplasma parvum (Ureaplasma urealyticum biotype 1)
Length = 521
Score = 99 bits (238), Expect = 1e-20
Identities = 53/117 (45%), Positives = 70/117 (59%)
Frame = +2
Query: 20 YGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAFA 199
YG AKI I +L NK+ K IV+ + P P GEGK+TT IGLV AL + G A
Sbjct: 22 YGNEIAKIKS--IKKL-NKKDSKLIVITSMNPNPAGEGKTTTAIGLVDAL-NKHGYKAIG 77
Query: 200 CMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMDARI 370
+R+PS GP FG+K S + P ++ NLH +GD HA+TAANNL+ A ++ I
Sbjct: 78 ALREPSMGPVFGMKGTGSGGGLSFLKPFDKINLHFSGDFHAITAANNLIVAVIENEI 134
>UniRef50_Q97CL3 Cluster: Formate--tetrahydrofolate ligase; n=4;
Thermoplasmatales|Rep: Formate--tetrahydrofolate ligase
- Thermoplasma volcanium
Length = 536
Score = 97.1 bits (231), Expect = 9e-20
Identities = 52/118 (44%), Positives = 74/118 (62%)
Frame = +2
Query: 20 YGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAFA 199
YGR AK+SL++ + NK+ K I+V +TPT GEGK+TT IGL QA + G+N
Sbjct: 21 YGRYMAKLSLNLQEV--NKKKAKLILVTAMTPTAAGEGKTTTTIGLGQAF-KKLGKNVAI 77
Query: 200 CMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMDARIF 373
+R+PS GP FG+K S+V P + NL TGD A++AA+NLL+A ++ I+
Sbjct: 78 AIREPSLGPCFGIKGGATGGGKSKVEPSDRINLLFTGDFPAISAAHNLLSAMINNHIY 135
>UniRef50_Q14NV0 Cluster: Probable formate-tetrahydrofolate ligase
protein; n=1; Spiroplasma citri|Rep: Probable
formate-tetrahydrofolate ligase protein - Spiroplasma
citri
Length = 535
Score = 81.4 bits (192), Expect = 5e-15
Identities = 44/123 (35%), Positives = 65/123 (52%)
Frame = +2
Query: 5 NEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRG 184
+++ +YG AK+ L K K+I+V I PT GEGK+T IG+ L G
Sbjct: 16 DDLIKYGDYMAKVKAFNFINLPKK--AKFILVTAINPTKAGEGKTTCSIGIADML-NHLG 72
Query: 185 RNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMDA 364
+R+PS GP FG+K + P E NLH TGD HA+T ANN++++ +D
Sbjct: 73 YQTTLALREPSLGPVFGLKGSATGGGECIMEPENEINLHYTGDFHAITTANNMVSSMIDN 132
Query: 365 RIF 373
++
Sbjct: 133 LLY 135
>UniRef50_Q8EUQ1 Cluster: Formate--tetrahydrofolate ligase; n=1;
Mycoplasma penetrans|Rep: Formate--tetrahydrofolate
ligase - Mycoplasma penetrans
Length = 530
Score = 81.0 bits (191), Expect = 6e-15
Identities = 41/100 (41%), Positives = 58/100 (58%)
Frame = +2
Query: 74 KRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAFACMRQPSQGPTFGVKXXXX 253
K K I+V I PTP GEGK+TTLIG+ L G+ + AC+RQPS GP FG+K
Sbjct: 32 KLESKLILVTSINPTPEGEGKTTTLIGINDCL-NYFGKESIACLRQPSMGPYFGIKGGAT 90
Query: 254 XXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAAQMDARIF 373
++ E+ N T D +A+ AANNL+ + ++ I+
Sbjct: 91 GSGKCEIQNPEKVNCGFTNDFYAIEAANNLIMSVIENEIY 130
>UniRef50_Q8G700 Cluster: Formate--tetrahydrofolate ligase; n=4;
Bifidobacterium|Rep: Formate--tetrahydrofolate ligase -
Bifidobacterium longum
Length = 505
Score = 52.0 bits (119), Expect = 3e-06
Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = +2
Query: 74 KRSGKYIVVAGITPTPL--GEGKSTTLIGLVQALCARRGRNAFACMRQPSQGPT-FGVKX 244
++ GK ++V TP GEGK+TT I L+ AL +RG +A A +RQPS G T G K
Sbjct: 34 RKHGKVVLVTADTPLKASRGEGKTTTTIALIDAL-NKRGIDATAVLRQPSMGITAAGSKG 92
Query: 245 XXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 352
+ + E + + G++ A+ AA NLL +
Sbjct: 93 GASGGGKASLTHPELIDWGLCGEMGAIEAAQNLLVS 128
>UniRef50_Q00SR1 Cluster: 10-formyltetra; n=1; Ostreococcus
tauri|Rep: 10-formyltetra - Ostreococcus tauri
Length = 467
Score = 42.3 bits (95), Expect = 0.003
Identities = 17/26 (65%), Positives = 22/26 (84%)
Frame = +2
Query: 296 LHMTGDIHAVTAANNLLAAQMDARIF 373
LH+TGDIHA+ A NL+AA +DAR+F
Sbjct: 2 LHLTGDIHAIGVATNLVAAAIDARVF 27
>UniRef50_Q8GJ02 Cluster: Formyltetrahydrofolate synthetase; n=121;
root|Rep: Formyltetrahydrofolate synthetase -
Eubacterium limosum
Length = 437
Score = 36.3 bits (80), Expect = 0.18
Identities = 16/22 (72%), Positives = 18/22 (81%)
Frame = +2
Query: 305 TGDIHAVTAANNLLAAQMDARI 370
TGDIHA+ AANNLLAA +D I
Sbjct: 78 TGDIHAIGAANNLLAAMLDNHI 99
>UniRef50_Q0ZQ16 Cluster: Formyl tetrahydrofolate synthetase; n=1;
uncultured microorganism|Rep: Formyl tetrahydrofolate
synthetase - uncultured microorganism
Length = 361
Score = 34.7 bits (76), Expect = 0.56
Identities = 14/23 (60%), Positives = 18/23 (78%)
Frame = +2
Query: 305 TGDIHAVTAANNLLAAQMDARIF 373
TGD HA+T ANNL++A +D IF
Sbjct: 2 TGDFHAITVANNLISACIDNHIF 24
>UniRef50_Q8L054 Cluster: Putative formyltetrahydrofolate
synthetase; n=76; Bacteria|Rep: Putative
formyltetrahydrofolate synthetase - uncultured bacterium
Length = 360
Score = 34.7 bits (76), Expect = 0.56
Identities = 15/22 (68%), Positives = 17/22 (77%)
Frame = +2
Query: 305 TGDIHAVTAANNLLAAQMDARI 370
TGD HA+ AANNLLAA +D I
Sbjct: 2 TGDFHAIGAANNLLAAMLDNHI 23
>UniRef50_Q6PPA4 Cluster: P-glycoprotein D; n=1; Leishmania
tarentolae|Rep: P-glycoprotein D - Leishmania tarentolae
(Sauroleishmania tarentolae)
Length = 1527
Score = 33.9 bits (74), Expect = 0.98
Identities = 29/69 (42%), Positives = 34/69 (49%)
Frame = +2
Query: 20 YGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAFA 199
Y AK L+ +D LR R G+ VV G P G GKST L L+ AL RGR A
Sbjct: 615 YYELHAKALLADVD-LRVPR-GRLTVVLG----PTGSGKSTLLDALIGALAVTRGR--VA 666
Query: 200 CMRQPSQGP 226
C R + P
Sbjct: 667 CSRNVTYVP 675
>UniRef50_Q4Q6D6 Cluster: P-glycoprotein e; n=7;
Trypanosomatidae|Rep: P-glycoprotein e - Leishmania
major
Length = 1677
Score = 33.9 bits (74), Expect = 0.98
Identities = 32/74 (43%), Positives = 37/74 (50%)
Frame = +2
Query: 5 NEVSQYGRTKAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRG 184
NE S Y K K L+ +D LR R G+ VV G P G GKST L L+ AL RG
Sbjct: 763 NEDSIYV-LKTKTLLADVD-LRVPR-GRLTVVLG----PTGSGKSTLLNALIGALAVTRG 815
Query: 185 RNAFACMRQPSQGP 226
R AC R + P
Sbjct: 816 R--VACSRSVAYVP 827
>UniRef50_Q4Q6D4 Cluster: Multidrug resistance protein, copy 1-like
protein; n=5; Leishmania|Rep: Multidrug resistance
protein, copy 1-like protein - Leishmania major
Length = 1554
Score = 33.9 bits (74), Expect = 0.98
Identities = 28/65 (43%), Positives = 34/65 (52%)
Frame = +2
Query: 32 KAKISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAFACMRQ 211
+AK L+ +D LR R G+ VV G P G GKST L L+ AL RGR AC R
Sbjct: 634 RAKTLLADVD-LRVPR-GRLTVVLG----PTGSGKSTLLNALIGALAVTRGR--VACSRS 685
Query: 212 PSQGP 226
+ P
Sbjct: 686 VAYVP 690
>UniRef50_Q5CN90 Cluster: Last step in pyrimidine biosynthesis
pathway; Ura8p; n=2; Cryptosporidium|Rep: Last step in
pyrimidine biosynthesis pathway; Ura8p - Cryptosporidium
hominis
Length = 670
Score = 33.5 bits (73), Expect = 1.3
Identities = 25/66 (37%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Frame = +2
Query: 23 GRTKA-KISLSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCAR-RGRNAF 196
GR K+ K++ S ++ L + R KYIVV G T + LG+G + + +G LC + RG N
Sbjct: 10 GRIKSPKLTTSSVNHLADDRVIKYIVVTGGTLSGLGKGIAISSLG----LCLKSRGYNVT 65
Query: 197 ACMRQP 214
A P
Sbjct: 66 AIKIDP 71
>UniRef50_Q9F3L3 Cluster: Acetyltransferase; n=3; Streptomyces|Rep:
Acetyltransferase - Streptomyces coelicolor
Length = 212
Score = 33.1 bits (72), Expect = 1.7
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +2
Query: 77 RSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGRNAF 196
R+ Y+ + G+ P GEG T LIG V C R G A+
Sbjct: 131 RAHAYLWMIGVVPERQGEGLGTALIGTVLDRCDREGLPAY 170
>UniRef50_UPI0000F2CC46 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 285
Score = 31.9 bits (69), Expect = 3.9
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = -1
Query: 219 WLGCRMHANALRPRRAHRACTKPIKVVLLPSP-SGVGVIPATTMYLPLRLL 70
+ G +MH R R H A P++V++LP P G V PA + PLR+L
Sbjct: 76 YFGHKMHV-LTRGARVHPALAFPLRVLILPGPLGGARVHPA--LAFPLRVL 123
Score = 30.7 bits (66), Expect = 9.1
Identities = 15/36 (41%), Positives = 21/36 (58%)
Frame = -1
Query: 177 RAHRACTKPIKVVLLPSPSGVGVIPATTMYLPLRLL 70
R H A P++V++LP P G G T + PLR+L
Sbjct: 199 RVHTALAFPLRVLILPGPLG-GARVHTALAFPLRVL 233
>UniRef50_A4FCM1 Cluster: Putative uncharacterized protein; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Putative
uncharacterized protein - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 209
Score = 31.9 bits (69), Expect = 3.9
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = -1
Query: 204 MHANALRPRRAHRACTKPIKVVLLPSPSGVGVIPATTMYLPLRLLRSRSM 55
+HA A+R R R + VV+ + + VG++P +YLP R+LR R++
Sbjct: 84 VHAEAVRVRSNIRV----LAVVVGVAVALVGLVPLALIYLPFRILRMRAL 129
>UniRef50_Q4K885 Cluster: Ais protein, putative; n=1; Pseudomonas
fluorescens Pf-5|Rep: Ais protein, putative -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 246
Score = 31.5 bits (68), Expect = 5.2
Identities = 18/59 (30%), Positives = 26/59 (44%)
Frame = -3
Query: 268 GVTAAGSTSLHSKSRSLARLSHARECVTSSPSTQSLHQTN*SGTFTFSQRCWCYTCDDN 92
G+T GS S R+ L A V SSP+T++ T + W TCD++
Sbjct: 113 GITQLGSHSASDLGRAFRTLGMAATDVISSPATRTRQTTEFMFNGAAQTQDWLATCDEH 171
>UniRef50_A4S262 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 835
Score = 31.5 bits (68), Expect = 5.2
Identities = 13/25 (52%), Positives = 15/25 (60%)
Frame = +2
Query: 68 RNKRSGKYIVVAGITPTPLGEGKST 142
R G YI+ + PTPLGEGK T
Sbjct: 431 RRTEDGSYILARVVGPTPLGEGKPT 455
>UniRef50_A7RJ10 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 721
Score = 31.5 bits (68), Expect = 5.2
Identities = 15/43 (34%), Positives = 22/43 (51%)
Frame = -2
Query: 188 YVLAEHTELAPNQLKWYFYLLPAVLVLYLRRQCICRCACYGVG 60
YVL H + + +F+L+ A+LVL L RC C+ G
Sbjct: 471 YVLCFHNKNIHTKYGMFFFLMMAMLVLLLLFTSASRCLCFQAG 513
>UniRef50_Q8YVT6 Cluster: All1888 protein; n=6; Nostocaceae|Rep:
All1888 protein - Anabaena sp. (strain PCC 7120)
Length = 1256
Score = 31.1 bits (67), Expect = 6.9
Identities = 18/34 (52%), Positives = 23/34 (67%)
Frame = +2
Query: 47 LSVIDRLRNKRSGKYIVVAGITPTPLGEGKSTTL 148
LSV+D + NK+S KY+V+ G P G GKST L
Sbjct: 292 LSVLDVVNNKQSYKYVVILG-DP---GSGKSTLL 321
>UniRef50_Q5GZX9 Cluster: Putative uncharacterized protein; n=12;
Xanthomonas|Rep: Putative uncharacterized protein -
Xanthomonas oryzae pv. oryzae
Length = 354
Score = 31.1 bits (67), Expect = 6.9
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 2/29 (6%)
Frame = +1
Query: 199 VHATTEPGTYFWSEGRCCRR--RLLPGYT 279
+H T W EGR C R RLLPG+T
Sbjct: 125 IHLTAPTKQLLWEEGRICDRLQRLLPGWT 153
>UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_27,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 552
Score = 31.1 bits (67), Expect = 6.9
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = -1
Query: 147 KVVLLPSPSGVGVIPATTMYLPLRLLRSRSMTDKEILALV 28
K+ LPSP G GV+P + +L + RS ++ D +++ LV
Sbjct: 231 KLPFLPSPMGKGVVPDSN-HLNVSAARSTALGDADVILLV 269
>UniRef50_Q48HY4 Cluster: Putative uncharacterized protein; n=1;
Pseudomonas syringae pv. phaseolicola 1448A|Rep:
Putative uncharacterized protein - Pseudomonas syringae
pv. phaseolicola (strain 1448A / Race 6)
Length = 226
Score = 30.7 bits (66), Expect = 9.1
Identities = 18/73 (24%), Positives = 31/73 (42%)
Frame = -3
Query: 274 NLGVTAAGSTSLHSKSRSLARLSHARECVTSSPSTQSLHQTN*SGTFTFSQRCWCYTCDD 95
N G+T GS+ RS + L A V +SP T++ + W Y CD+
Sbjct: 89 NDGITRYGSSVSTDVGRSFSELGLAHTDVITSPLTRTAQTAQAMFGHPVEAQEWLYNCDE 148
Query: 94 NVFAAALVTESVD 56
+ + +S++
Sbjct: 149 TMLNEVVAHKSLN 161
>UniRef50_Q0WYD4 Cluster: Phytochromobilin synthase; n=1;
Physcomitrella patens|Rep: Phytochromobilin synthase -
Physcomitrella patens (Moss)
Length = 405
Score = 30.7 bits (66), Expect = 9.1
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 5/57 (8%)
Frame = +2
Query: 71 NKRSGKYIVVAGITPTPLGEGKSTTLIGLVQALCARRGR-----NAFACMRQPSQGP 226
N RSG ++V G + +G+ + + A+C RRGR NA+ R GP
Sbjct: 27 NGRSGSTVIVGGALWSSIGKSCTGAACFVPSAVCVRRGRVVCHGNAWVLRRDQKGGP 83
>UniRef50_A2QEI5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus niger|Rep: Putative uncharacterized protein
- Aspergillus niger
Length = 231
Score = 30.7 bits (66), Expect = 9.1
Identities = 13/24 (54%), Positives = 15/24 (62%)
Frame = +1
Query: 73 QAQRQIHCRRRYNTNTAGRR*KYH 144
Q R IHC R+YNT RR KY+
Sbjct: 41 QGYRPIHCDRQYNTTLQTRRQKYN 64
>UniRef50_Q7Z5H4 Cluster: Vomeronasal type-1 receptor 5; n=3;
Homo/Pan/Gorilla group|Rep: Vomeronasal type-1 receptor
5 - Homo sapiens (Human)
Length = 357
Score = 30.7 bits (66), Expect = 9.1
Identities = 16/49 (32%), Positives = 24/49 (48%)
Frame = -2
Query: 236 LQK*VPGSVVACTRMRYVLAEHTELAPNQLKWYFYLLPAVLVLYLRRQC 90
LQ V S A + + + A++ Q+ W+ YL P L+L RQC
Sbjct: 304 LQVIVANSYAAISPLMLIYADNQIFKTLQMLWFKYLSPPKLMLKFNRQC 352
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 412,492,202
Number of Sequences: 1657284
Number of extensions: 8673967
Number of successful extensions: 23314
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 22690
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 23275
length of database: 575,637,011
effective HSP length: 91
effective length of database: 424,824,167
effective search space used: 14019197511
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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