Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= I10A02NGRL0005_G11
(644 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 294 1e-78
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 282 4e-75
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 268 6e-71
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 258 6e-68
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 255 8e-67
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 254 2e-66
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 253 3e-66
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 241 1e-62
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 241 1e-62
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 235 5e-61
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 231 1e-59
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 227 2e-58
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 225 7e-58
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 222 5e-57
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 219 6e-56
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 218 8e-56
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 217 2e-55
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 217 2e-55
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 215 8e-55
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 214 2e-54
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 214 2e-54
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 213 3e-54
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 212 7e-54
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 212 7e-54
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 208 7e-53
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 207 2e-52
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 207 2e-52
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 203 3e-51
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 203 3e-51
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 199 4e-50
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 195 9e-49
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 192 5e-48
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 191 1e-47
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 190 2e-47
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 190 3e-47
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 189 4e-47
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 189 4e-47
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 189 6e-47
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 188 8e-47
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 188 1e-46
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 188 1e-46
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 186 4e-46
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 184 1e-45
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 184 1e-45
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 184 2e-45
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 182 7e-45
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 181 1e-44
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 181 2e-44
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 180 3e-44
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 178 8e-44
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 176 3e-43
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 176 4e-43
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 176 4e-43
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 176 4e-43
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 176 4e-43
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 175 6e-43
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 175 8e-43
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 174 2e-42
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 173 3e-42
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 172 5e-42
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 172 7e-42
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 171 9e-42
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 171 2e-41
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 170 2e-41
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 170 3e-41
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 170 3e-41
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 169 7e-41
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 168 9e-41
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 168 1e-40
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 167 3e-40
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 166 5e-40
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 166 5e-40
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 166 5e-40
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 165 6e-40
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 164 1e-39
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 163 3e-39
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 163 4e-39
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 162 8e-39
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 161 1e-38
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 161 1e-38
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 161 2e-38
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 161 2e-38
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 160 2e-38
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 160 3e-38
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 159 4e-38
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 159 7e-38
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 158 9e-38
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 158 9e-38
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 158 9e-38
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 156 4e-37
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 156 5e-37
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 155 7e-37
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 155 9e-37
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 154 2e-36
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 154 2e-36
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 154 2e-36
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 154 2e-36
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 154 2e-36
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 153 3e-36
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 153 3e-36
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 153 3e-36
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 153 3e-36
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 152 6e-36
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 152 8e-36
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 151 1e-35
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 151 2e-35
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 150 2e-35
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 150 3e-35
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 149 6e-35
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 149 7e-35
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 149 7e-35
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 148 1e-34
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 148 1e-34
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 148 1e-34
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 147 2e-34
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 147 2e-34
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 147 2e-34
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 146 3e-34
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 146 4e-34
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 144 1e-33
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 144 2e-33
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 144 2e-33
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 143 4e-33
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 142 7e-33
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 142 9e-33
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 141 1e-32
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 141 1e-32
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 140 3e-32
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 140 3e-32
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 140 3e-32
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 140 3e-32
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 140 3e-32
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 139 5e-32
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 139 6e-32
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 139 6e-32
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 136 3e-31
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 136 4e-31
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 136 4e-31
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 135 7e-31
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 134 2e-30
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 133 4e-30
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 133 4e-30
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 132 7e-30
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 132 7e-30
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 132 9e-30
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 132 9e-30
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 132 9e-30
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 131 1e-29
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 131 2e-29
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 131 2e-29
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 131 2e-29
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 130 2e-29
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 130 2e-29
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 130 3e-29
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 130 3e-29
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 130 3e-29
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 130 4e-29
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 129 6e-29
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 128 9e-29
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 128 9e-29
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 128 1e-28
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 128 1e-28
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 127 2e-28
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 127 3e-28
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 127 3e-28
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 126 3e-28
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 126 3e-28
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 126 3e-28
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 126 3e-28
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 125 8e-28
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 125 8e-28
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 124 1e-27
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 124 1e-27
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 124 2e-27
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 124 2e-27
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 124 2e-27
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 124 2e-27
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 124 2e-27
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 124 2e-27
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 124 2e-27
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 124 2e-27
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 123 3e-27
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 122 6e-27
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 122 6e-27
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 122 6e-27
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 122 7e-27
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 122 1e-26
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 122 1e-26
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 73 2e-26
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 120 2e-26
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 120 2e-26
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 120 2e-26
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 120 3e-26
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 120 3e-26
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 120 3e-26
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 120 3e-26
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 108 4e-26
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 120 4e-26
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 119 7e-26
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 119 7e-26
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 119 7e-26
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 118 9e-26
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 118 1e-25
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 118 2e-25
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 117 2e-25
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 117 2e-25
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 116 4e-25
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 116 4e-25
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 116 6e-25
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 115 1e-24
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 114 1e-24
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 114 2e-24
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 113 3e-24
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 113 3e-24
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 113 3e-24
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 113 5e-24
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 112 6e-24
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 111 1e-23
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 111 1e-23
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 111 2e-23
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 111 2e-23
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 110 2e-23
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 109 6e-23
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 109 7e-23
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 109 7e-23
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 109 7e-23
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 109 7e-23
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 108 1e-22
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 107 2e-22
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 107 2e-22
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 107 2e-22
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 107 3e-22
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 106 4e-22
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 106 5e-22
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 106 5e-22
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 106 5e-22
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 105 7e-22
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 105 7e-22
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 105 9e-22
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 105 9e-22
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 104 2e-21
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 104 2e-21
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 104 2e-21
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 104 2e-21
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 103 3e-21
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 103 3e-21
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 103 3e-21
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 103 5e-21
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 102 9e-21
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 100 3e-20
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 99 1e-19
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 99 1e-19
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 99 1e-19
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 98 1e-19
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 97 2e-19
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 97 3e-19
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 97 3e-19
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 97 4e-19
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 96 6e-19
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 96 6e-19
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 95 1e-18
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 95 1e-18
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 95 1e-18
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 95 1e-18
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 95 1e-18
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 94 2e-18
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 94 2e-18
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 94 3e-18
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 93 5e-18
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 93 5e-18
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 92 9e-18
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 92 1e-17
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 90 4e-17
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 90 5e-17
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 89 1e-16
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 89 1e-16
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 89 1e-16
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 87 3e-16
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 87 3e-16
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 86 6e-16
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 84 2e-15
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 84 3e-15
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 83 4e-15
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 83 4e-15
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 83 4e-15
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 83 7e-15
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 82 1e-14
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 82 1e-14
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 82 1e-14
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 81 2e-14
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 81 2e-14
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 81 3e-14
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 79 7e-14
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 79 1e-13
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 78 2e-13
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 76 6e-13
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 76 8e-13
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 74 3e-12
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 74 3e-12
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 74 3e-12
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 74 3e-12
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 74 3e-12
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 73 6e-12
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 72 1e-11
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 71 2e-11
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 71 2e-11
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 71 3e-11
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 71 3e-11
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 70 4e-11
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 70 4e-11
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 70 6e-11
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 70 6e-11
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 69 1e-10
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 68 2e-10
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 68 2e-10
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 67 3e-10
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 67 4e-10
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 66 5e-10
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 66 5e-10
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 65 1e-09
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 65 1e-09
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 65 2e-09
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 65 2e-09
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 64 4e-09
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 63 5e-09
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 63 5e-09
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 63 6e-09
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 62 8e-09
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 62 8e-09
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 62 8e-09
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08
UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 62 1e-08
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 61 2e-08
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 60 3e-08
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 60 4e-08
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 60 6e-08
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 60 6e-08
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 59 8e-08
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 58 1e-07
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 58 1e-07
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07
UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 56 6e-07
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 56 6e-07
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 56 7e-07
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 56 1e-06
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 56 1e-06
UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ... 56 1e-06
UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ... 55 1e-06
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 55 1e-06
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 55 2e-06
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 55 2e-06
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 54 2e-06
UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 54 2e-06
UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 53 7e-06
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 53 7e-06
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 52 9e-06
UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 52 9e-06
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 52 9e-06
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 52 9e-06
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 52 9e-06
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 1e-05
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 52 1e-05
UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep... 52 1e-05
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 52 1e-05
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 52 2e-05
UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 51 2e-05
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 51 2e-05
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 51 2e-05
UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 51 2e-05
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 51 3e-05
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 51 3e-05
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 51 3e-05
UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 50 4e-05
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 50 4e-05
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 50 5e-05
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 50 5e-05
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 50 5e-05
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 50 5e-05
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 50 6e-05
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 50 6e-05
UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 50 6e-05
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 50 6e-05
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 49 8e-05
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 49 8e-05
UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth... 49 8e-05
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 49 1e-04
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 49 1e-04
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 49 1e-04
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 49 1e-04
UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 40 1e-04
UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 48 1e-04
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 48 1e-04
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 48 2e-04
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 2e-04
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 48 2e-04
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 48 2e-04
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 48 2e-04
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 48 3e-04
UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 48 3e-04
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 3e-04
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 48 3e-04
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 47 3e-04
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 47 3e-04
UniRef50_A5GMY9 Cluster: Aldo/keto reductase family protein; n=2... 47 3e-04
UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob... 47 3e-04
UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter... 47 4e-04
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 47 4e-04
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 47 4e-04
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 47 4e-04
UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 47 4e-04
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 46 6e-04
UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 46 6e-04
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 46 6e-04
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 46 6e-04
UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 46 6e-04
UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su... 46 6e-04
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 46 8e-04
UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 46 8e-04
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 45 0.001
UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 45 0.001
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 45 0.001
UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 45 0.001
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 45 0.002
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 45 0.002
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 45 0.002
UniRef50_Q6A7U3 Cluster: Putative oxidoreductase; n=1; Propionib... 44 0.002
UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 44 0.002
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 44 0.002
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 44 0.003
UniRef50_Q01Z07 Cluster: Aldo/keto reductase; n=4; cellular orga... 44 0.003
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 44 0.004
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 44 0.004
UniRef50_Q9QWA5 Cluster: Aldose reductase; n=5; Euarchontoglires... 44 0.004
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 44 0.004
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 43 0.006
UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 43 0.006
UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll... 43 0.006
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 43 0.006
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 43 0.006
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 43 0.006
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 43 0.006
UniRef50_Q7UZ40 Cluster: Putative oxidoreductase-possibly Aldo/k... 43 0.007
UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro... 43 0.007
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 43 0.007
UniRef50_Q1MJ49 Cluster: Putative general stress protein; n=2; R... 43 0.007
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 43 0.007
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 43 0.007
UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 43 0.007
UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1; Leptospir... 43 0.007
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 43 0.007
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 43 0.007
UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 43 0.007
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 43 0.007
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 42 0.010
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.010
UniRef50_Q1FHF4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 42 0.010
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 42 0.010
UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 42 0.010
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 42 0.010
UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 42 0.010
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 42 0.010
UniRef50_Q28R03 Cluster: Aldo/keto reductase; n=4; Alphaproteoba... 42 0.013
UniRef50_Q025S3 Cluster: Aldo/keto reductase precursor; n=1; Sol... 42 0.013
UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 42 0.013
UniRef50_A7DS16 Cluster: Aldo/keto reductase; n=1; Candidatus Ni... 42 0.013
UniRef50_Q09923 Cluster: Aldo-keto reductase yakc [NADP+]; n=13;... 42 0.013
UniRef50_Q98JS9 Cluster: Aldo/keto reductase; n=39; Bacteria|Rep... 42 0.017
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 42 0.017
UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 42 0.017
UniRef50_A6PQ08 Cluster: Aldo/keto reductase precursor; n=1; Vic... 42 0.017
UniRef50_A4EK59 Cluster: Putative oxidoreductase protein; n=1; R... 42 0.017
UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 41 0.022
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 41 0.022
UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 41 0.022
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 41 0.022
UniRef50_Q08VS2 Cluster: Twin-arginine translocation pathway sig... 41 0.022
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 41 0.022
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 41 0.022
UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 41 0.022
UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam... 41 0.022
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 41 0.029
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 41 0.029
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 41 0.029
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 41 0.029
UniRef50_A6DNQ2 Cluster: YqkF; n=1; Lentisphaera araneosa HTCC21... 41 0.029
UniRef50_A1ZSV4 Cluster: Oxidoreductase, aldo/keto reductase fam... 41 0.029
UniRef50_Q9SAC2 Cluster: T16B5.5 protein; n=23; Magnoliophyta|Re... 41 0.029
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 41 0.029
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 294 bits (721), Expect = 1e-78
Identities = 131/203 (64%), Positives = 155/203 (76%), Gaps = 1/203 (0%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
VP NG IP+ G+GTW S PG+V QAVKDAID+GYRHIDCA VY NE EVGE I
Sbjct: 6 VPNAIFKNGNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAA 65
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
KI EGVVKREDLF+TSKLWNTFHRPDLV GA + +L+NL +DYLDLYLIHWP Y+E
Sbjct: 66 KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTE 125
Query: 398 IFPTDADGK-IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
+FP DGK FSD DYVDTW +E LV GLVR++GVSNFN+KQ+QR+LD A + P T
Sbjct: 126 LFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPAT 185
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQ+ECHPYL+Q ++ FC ++ I
Sbjct: 186 NQIECHPYLHQSKITTFCAEKGI 208
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 282 bits (692), Expect = 4e-75
Identities = 129/204 (63%), Positives = 154/204 (75%), Gaps = 1/204 (0%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
S P LS+G +P++G+GTW+S P V QAVKDAIDIGYRH DCA +YGNE VG AI+
Sbjct: 2 STPSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIR 61
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
KIQEG+V R++LFITSKLWNTFH+P+LVR A E SLRNL IDYLDLYL+HWP AYK D
Sbjct: 62 EKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGD 121
Query: 395 AIFPTDAD-GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
++PT D GK F D+DY+DTWKA+E LV GLV ++GVSNFN KQ+ R+L A +KPV
Sbjct: 122 NLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKLKPV 181
Query: 572 TNQVECHPYLNQKRLKQFCEDRDI 643
Q+ECHPYL QK L C D I
Sbjct: 182 MLQIECHPYLRQKSLITLCYDNAI 205
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 268 bits (658), Expect = 6e-71
Identities = 122/205 (59%), Positives = 153/205 (74%), Gaps = 2/205 (0%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
S P LSNG +P++G+GTW+S P VTQAVKDAIDIGYRH DCA +YGNE +VG A++
Sbjct: 2 STPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALR 61
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-D 391
K+ EGVV R++LFITSKLWNT H+PDLVR A E S+RNL + YL+LYL+HWP AYK
Sbjct: 62 EKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGS 121
Query: 392 DAIFPTDAD-GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
D ++PT D K F D+DYVDTW+A+E LV GL +++GVSNFN +Q+ R+L A +KP
Sbjct: 122 DNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKP 181
Query: 569 VTNQVECHPYLNQKRLKQFCEDRDI 643
V Q+ECHPYL+QK L C D I
Sbjct: 182 VVLQIECHPYLSQKPLITLCYDNAI 206
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 258 bits (633), Expect = 6e-68
Identities = 115/199 (57%), Positives = 150/199 (75%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+NG K+P +G+GTWKS PG+VT+AVK AID+GYRHIDCA VY NEKEVG A++ K++E
Sbjct: 7 LNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQ 66
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
VVKR+DLFI SKLW TFH +V+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLD 126
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 586
A G + SD D+VDTW A+E LV GLV+++GVSNFN Q++RIL+ + KP NQ+E
Sbjct: 127 ASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIE 186
Query: 587 CHPYLNQKRLKQFCEDRDI 643
CHPYL Q++L ++C + I
Sbjct: 187 CHPYLTQEKLIEYCHSKGI 205
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 255 bits (624), Expect = 8e-67
Identities = 116/200 (58%), Positives = 148/200 (74%), Gaps = 2/200 (1%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL GAK+P++G+GTWKS P +V +AVK AID GYRHIDCA+VY NE EVGEAI+ KIQE
Sbjct: 6 TLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQE 65
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
VKREDLFI SKLW+TF LV+ A + +L +L +DYLDLYLIHWPQ ++ + PT
Sbjct: 66 KAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFLPT 125
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQV 583
D G I S ++D W+A+E LV GLV++LGVSNFN Q++R+L+ + KPVTNQV
Sbjct: 126 DDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQV 185
Query: 584 ECHPYLNQKRLKQFCEDRDI 643
ECHPYL Q++L Q+C + I
Sbjct: 186 ECHPYLTQEKLTQYCHSKGI 205
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 254 bits (621), Expect = 2e-66
Identities = 112/199 (56%), Positives = 149/199 (74%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+NGAK+P++G+GTWKS PG+VT+AVK AID+GYRHIDCA VY NE EVG AI+ K++E
Sbjct: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
VVKRE+LFI SKLW T+H LV+GA + +L +L +DYLDLYLIHWP +K FP D
Sbjct: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVE 586
G + SD + +DTW A+E LV GLV+++G+SNFN Q++ IL+ + KP NQ+E
Sbjct: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
Query: 587 CHPYLNQKRLKQFCEDRDI 643
CHPYL Q++L Q+C+ + I
Sbjct: 187 CHPYLTQEKLIQYCQSKGI 205
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 253 bits (619), Expect = 3e-66
Identities = 112/202 (55%), Positives = 150/202 (74%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
VP T ++G K+P+IG+GT+ SKPGEV +AVK AI++GYRH+D AF Y NEKE+G AI+
Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIRE 62
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
KI +G +KRED+F+T+KLW H+ D V A + SL NL DY+DL+L+HWP A+K DA
Sbjct: 63 KINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGDA 122
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
+ P DA GKI+FSD DY++TWK +E GL RS+G+SNFNS+Q+ R+L +A +KPV N
Sbjct: 123 LTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNN 182
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVE LNQK L +FC+ +I
Sbjct: 183 QVEVTMNLNQKPLIEFCKKHEI 204
Score = 173 bits (421), Expect = 3e-42
Identities = 85/165 (51%), Positives = 113/165 (68%), Gaps = 1/165 (0%)
Frame = +2
Query: 152 YRHIDCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRN 331
YRHID A++Y NEK +G AI+ KI++G VKREDLF+T+KL H+ V A + SL +
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 332 LNIDYLDLYLIHWP-QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLG 508
L +DY+DLYLIHWP + Y + +A GK+ SD DY++TWK +E GL RS+G
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHN----KNASGKLLLSDTDYLETWKGMEECKRQGLARSIG 416
Query: 509 VSNFNSKQLQRILDNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
VSNFNS+Q+ R+L+ A +KPV NQVE LNQK L +FC+ DI
Sbjct: 417 VSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDI 461
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 241 bits (590), Expect = 1e-62
Identities = 110/198 (55%), Positives = 142/198 (71%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L G K+P+IG+GTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+K + G
Sbjct: 8 LHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPG 67
Query: 233 -VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V RE+LF+TSKLWNT H P+ V AL +L +L ++YLDLYL+HWP A++ D FP
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPK 127
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+ADG I + Y +TWKALE LV GLV++LG+SNFNS+Q+ IL ASV+P QVEC
Sbjct: 128 NADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVEC 187
Query: 590 HPYLNQKRLKQFCEDRDI 643
HPYL Q L C+ R +
Sbjct: 188 HPYLAQNELIAHCQARGL 205
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 241 bits (589), Expect = 1e-62
Identities = 106/197 (53%), Positives = 140/197 (71%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L++G IP IG+GTW+SKPGEV A+K A+ GYRHIDCA VY N+KEVGEA+K + EG
Sbjct: 7 LNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEG 66
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
VKRE+LFITSK+WNTFH +++ L +L + Y+DL LIHWPQ Y E +FP
Sbjct: 67 KVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAG 126
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
+GK+++SDVDY++TWKA E G RS+G+SNF Q+QR+ D A VKP QVE H
Sbjct: 127 ENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELH 186
Query: 593 PYLNQKRLKQFCEDRDI 643
PY Q +L++FC+++ I
Sbjct: 187 PYFTQVKLREFCKEKGI 203
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 235 bits (576), Expect = 5e-61
Identities = 112/202 (55%), Positives = 143/202 (70%), Gaps = 5/202 (2%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTW---KSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
L++G K+PVIG GT+ K + K AID+GYRHIDCAF+YGNE+EVG AI+ KI
Sbjct: 11 LNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIRAKI 70
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 403
+G VKRED+F T KLW+T H P+ VR ALE SL++L +DY+DL++IH P +K D +F
Sbjct: 71 ADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGDDLF 130
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKPVTN 577
P D +GK + + D DTWKALE GLVRS+GVSNFN KQL+ IL+ KPV N
Sbjct: 131 PADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCN 190
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVECH YLNQ +L +FC+ +DI
Sbjct: 191 QVECHVYLNQSKLLEFCKSKDI 212
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 231 bits (565), Expect = 1e-59
Identities = 114/206 (55%), Positives = 144/206 (69%), Gaps = 4/206 (1%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
+P L+NG ++P IG+GT SK E +AV AID G+RHID A+ Y NE VG AI+
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRA 65
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK---- 385
KI+EGVV RE+LF+T+KLWNTFH PD V A SL +L +DY+DL+LIH P Y+
Sbjct: 66 KIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGW 125
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
+ + P D +G + SD DYVDTWKA+E L+ G V S+GVSNFNS+QL+RIL N VK
Sbjct: 126 DPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILANCRVK 185
Query: 566 PVTNQVECHPYLNQKRLKQFCEDRDI 643
PVTNQVEC +NQK L +FC +RDI
Sbjct: 186 PVTNQVECSARINQKLLIEFCMERDI 211
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 227 bits (555), Expect = 2e-58
Identities = 111/209 (53%), Positives = 148/209 (70%), Gaps = 5/209 (2%)
Frame = +2
Query: 32 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAI 211
T VP SNG +IPV+G GT+ ++ G+ + VK AID+GYRHID AF+Y NE E+G+AI
Sbjct: 3 TQVPTVRFSNGYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQAI 62
Query: 212 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-- 385
+ KI EGV++RED+F+T+KLWNTFH P V A S L+I Y+DL+L+H P +
Sbjct: 63 RDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQFS 122
Query: 386 --EDDAIFPTDADGKIQFSDVDYVDTWKALEPLV-CHGLVRSLGVSNFNSKQLQRILDNA 556
E + P DA G + FSDVDYV+TWKA+E LV G VRS+G+SNFNS+Q++RIL A
Sbjct: 123 GYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERILQIA 182
Query: 557 SVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
+VKPV NQVE +P +Q++L FC+ R I
Sbjct: 183 TVKPVNNQVEANPGYDQRKLIAFCQARGI 211
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 225 bits (550), Expect = 7e-58
Identities = 102/200 (51%), Positives = 141/200 (70%), Gaps = 2/200 (1%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWK--SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
TLS+G K+PV+G+GTW+ + P EV AVK AID GYRH DCA YGNE E+G+AI+ KI
Sbjct: 9 TLSDGNKVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQEKI 68
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 403
+GVVKREDLF+ +K+WN + +LV A + SL+ L + Y+DLYL+HWP +Y
Sbjct: 69 DQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPILYQYI 128
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 583
+ +VDY++TW+ +E + GL RS+GVSNFNS+QL R+L++AS+KPV NQ+
Sbjct: 129 VLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKPVMNQI 188
Query: 584 ECHPYLNQKRLKQFCEDRDI 643
E H LNQK+L++FC + I
Sbjct: 189 ELHINLNQKKLREFCASKSI 208
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 222 bits (543), Expect = 5e-57
Identities = 106/212 (50%), Positives = 142/212 (66%), Gaps = 21/212 (9%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRED 250
IP +G+ +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG I+ KI+EG V+RED
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 251 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 403
LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 404 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R+L+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 554 ASV--KPVTNQVECHPYLNQKRLKQFCEDRDI 643
+ KP+TNQ+ECHPYL QK L FC+ RD+
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDV 215
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 219 bits (534), Expect = 6e-56
Identities = 103/202 (50%), Positives = 144/202 (71%), Gaps = 5/202 (2%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPG---EVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
L++G IPV+G GT+ ++ + ++ K AID+G+ HIDC+ +Y NE+E+G+AI +KI
Sbjct: 10 LNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKI 69
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 403
++G VKRED+F TSKLW+T HRP+LVR +LE SLR LN+DY+DLYLIH+P + K + +
Sbjct: 70 EDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELL 129
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTN 577
P D G + F VD DTW+A+E GL +S+GVSNFN +QL+ IL+ + KPV N
Sbjct: 130 PKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVECH YLNQ +L +C+ DI
Sbjct: 190 QVECHLYLNQSKLLAYCKMNDI 211
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 218 bits (533), Expect = 8e-56
Identities = 100/197 (50%), Positives = 141/197 (71%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+ GA IP + +GTW+S EV AV+ AI++GYRHIDCA +YGNE E+GEA+ + EG
Sbjct: 10 LNTGASIPAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVLTEG 69
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
VKRE+LF+TSKLW H PD V A + +L+NL +DYLDLYLIH P A+K+ + +
Sbjct: 70 KVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLPHSI 129
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
A+G I ++ +TW+A+E LV GL +++GVSNF+ K+L ++L+ AS+ P NQVE H
Sbjct: 130 AEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELH 189
Query: 593 PYLNQKRLKQFCEDRDI 643
PYL Q++LK+FC+ + I
Sbjct: 190 PYLPQEKLKEFCDSKGI 206
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 217 bits (530), Expect = 2e-55
Identities = 99/198 (50%), Positives = 137/198 (69%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
T++ GAKIP +G GTW++KP EV AV+ A+ GYRHIDCA +Y NE EVG I+ +
Sbjct: 8 TINTGAKIPAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNGIR----K 63
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V RE++FIT KLWNT H P+ V AL+ +L++L + YLDLYL+HWP A+K D FP
Sbjct: 64 SGVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGDKWFPL 123
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+ DG +++DY+ T++A+E L+ G VR++GVSNFN ++L+ +L SV P NQ+E
Sbjct: 124 NDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIEA 183
Query: 590 HPYLNQKRLKQFCEDRDI 643
HPYL Q L QFC+ + I
Sbjct: 184 HPYLQQPDLLQFCQSKGI 201
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 217 bits (530), Expect = 2e-55
Identities = 103/202 (50%), Positives = 144/202 (71%), Gaps = 5/202 (2%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDA---IDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
L++G IP +G GT+K K +++++ A +D+GYRH+D A+ Y E+E+G+AI++KI
Sbjct: 10 LNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKI 69
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 403
+ GVVKREDLFIT+KLW T RP+LV+ ALE SL+ L +DY+DLY++H+P K D F
Sbjct: 70 KAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDF 129
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTN 577
P + GK VD+ DTW+ LE GLV+S+GVSNFN +QL+RIL+ + KPV N
Sbjct: 130 PVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCN 189
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVECH YLNQ++L +CE +DI
Sbjct: 190 QVECHLYLNQRKLLDYCESKDI 211
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 215 bits (525), Expect = 8e-55
Identities = 100/187 (53%), Positives = 133/187 (71%), Gaps = 2/187 (1%)
Frame = +2
Query: 89 GTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSK 268
GT KS +V A K A+D+GYRH+D AF+Y +E VG+A + K +G +KREDLF TSK
Sbjct: 47 GTEKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSK 106
Query: 269 LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDY 448
LWNTFH+P LVR ALE +L L +DY+DLYLIH P ++K + +FP + DG F D
Sbjct: 107 LWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDL 166
Query: 449 VDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECHPYLNQKRLKQ 622
+ TW+ALE GLV+S+GVSNFN +QL+ IL+ + KPV NQ+ECHPYLNQK++ +
Sbjct: 167 LQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLE 226
Query: 623 FCEDRDI 643
FC+ +DI
Sbjct: 227 FCKSKDI 233
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 214 bits (522), Expect = 2e-54
Identities = 97/200 (48%), Positives = 134/200 (67%), Gaps = 2/200 (1%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL +G +P++G+GTWK K EV A+ A+D GYRH DCA +YGNEKEVG A++ +Q
Sbjct: 6 TLPSGHAMPLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQR 65
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--DDAIF 403
+KRED+FIT+K+WNTFH + V SL +L +DY+DLY++HWP ++ +F
Sbjct: 66 LGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVMF 125
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 583
P G I +SDV Y++TW A+E LV G +SLG+SNFNSKQL +L +++V P QV
Sbjct: 126 PRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVLQV 185
Query: 584 ECHPYLNQKRLKQFCEDRDI 643
E HP+L Q L FC +R +
Sbjct: 186 ESHPFLPQVELLNFCRERSV 205
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 214 bits (522), Expect = 2e-54
Identities = 100/198 (50%), Positives = 130/198 (65%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL N +P++G GTW+ G V+ AI GYRHIDCA +YGNEKEVGE I+ I +
Sbjct: 5 TLRNKQTLPLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQ 64
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
GVVKREDLF+TSKLWNT H V A +L +L +DYLDLYLIHW A++ D + P
Sbjct: 65 GVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPL 124
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
D DG +FS + +TW+A+E LV GLV+S+GV+NF + L +L A +KP +Q+E
Sbjct: 125 DDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIEL 184
Query: 590 HPYLNQKRLKQFCEDRDI 643
HPYL Q L FC ++I
Sbjct: 185 HPYLAQNDLVAFCYSQNI 202
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 213 bits (520), Expect = 3e-54
Identities = 107/203 (52%), Positives = 139/203 (68%), Gaps = 6/203 (2%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
LS+G IP+IG+GT+ KS P G +VK AID GYRHID A++Y NE EVGEAI+ K
Sbjct: 12 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 71
Query: 221 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 400
I EG V+RED+F KLW T H P++VR LE +LR L +DY+DLY+I P A+K D I
Sbjct: 72 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEI 131
Query: 401 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVT 574
+P D +GK + + TW+A+E GLV+SLGVSNFN +QL+ IL+ + KPV+
Sbjct: 132 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVS 191
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQVECHPY Q +L +FC+ DI
Sbjct: 192 NQVECHPYFTQPKLLKFCQQHDI 214
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 212 bits (517), Expect = 7e-54
Identities = 107/228 (46%), Positives = 143/228 (62%), Gaps = 26/228 (11%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
+P TL+ GA +PV+G+GTWKS G T+AVK AI GYRHID A+VY NE EVG ++
Sbjct: 2 IPSVTLNTGALMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQA 61
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--- 388
I +GVVKRE+LFI SKLW TFH P LVRGA E +L +LN+DY+DLYL+H+P
Sbjct: 62 MIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMGALSATL 121
Query: 389 -----DDAI----------------FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSL 505
D I FP D ++ ++DTW+A+E LV GL +++
Sbjct: 122 DLTSLTDVIPTVFRDFSPLQPGEDPFPLDEHNQLICDGTSFLDTWEAMEELVDDGLAKAI 181
Query: 506 GVSNFNSKQLQRILDNASV--KPVTNQVECHPYLNQKRLKQFCEDRDI 643
G+SNFN Q++ +L+ + KP TNQ+ECHP+LNQ++L FC R I
Sbjct: 182 GISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHFCRSRGI 229
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 212 bits (517), Expect = 7e-54
Identities = 106/202 (52%), Positives = 137/202 (67%), Gaps = 1/202 (0%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
P LS+G KIP++G GTWK++ V +AV+ A+D GYRHIDCA VY NEKEVGEA K
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKK 62
Query: 221 IQ-EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
E VKRED+FITSKLWNTFH+ + VR ALE +L +L + YLDLYL+HWP A++
Sbjct: 63 FTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
T G Q V +TW+ +E LV GLV+S+G+SNFN + L +L A +KP N
Sbjct: 123 DIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAAN 179
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVE HP+L+Q LK+FC+ +I
Sbjct: 180 QVELHPFLSQPELKKFCDKHNI 201
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 208 bits (509), Expect = 7e-53
Identities = 95/199 (47%), Positives = 138/199 (69%), Gaps = 1/199 (0%)
Frame = +2
Query: 29 MTSV-PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE 205
MT++ P L+NG ++P +G+GTWKS + + + A+D+GYRH+D AFVY NE EVG+
Sbjct: 1 MTNLAPTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQ 60
Query: 206 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
AI KI EGVV RE++F+T+KL H P LV A +SL NL ++Y+DLYL+H P K
Sbjct: 61 AISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQK 120
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
+ ++ G ++ +DVDY+DTW+ +E LV GL RS+G+SNFN+ Q +R+L N ++
Sbjct: 121 FHN---DSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIR 177
Query: 566 PVTNQVECHPYLNQKRLKQ 622
PV NQVECHP Q++L++
Sbjct: 178 PVVNQVECHPGFQQRQLRE 196
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 207 bits (506), Expect = 2e-52
Identities = 99/198 (50%), Positives = 128/198 (64%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
+ NG ++P+IG+GTWKS PGEV +AV A++ GYRH+DCA +Y NE EVG A+
Sbjct: 5 SFENGDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFDA 64
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G ++R+D+++TSKLWN H PD VR ALE +L +L +D LDLYLIHWP A + + FP
Sbjct: 65 GGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVAL-QPEVDFPE 123
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
D + V +TW A+E L GLVR +GVSNF+ LQ ILD V+P NQVE
Sbjct: 124 SPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVEM 183
Query: 590 HPYLNQKRLKQFCEDRDI 643
HPYL Q L F E +I
Sbjct: 184 HPYLPQPELVSFAEAHNI 201
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 207 bits (505), Expect = 2e-52
Identities = 101/199 (50%), Positives = 131/199 (65%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L G K+P++G GTW+ KP EV + ++ AID GYRHID A +YGNEK VG+ IK KI +G
Sbjct: 10 LPGGRKLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDDG 69
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
+KREDLF+TSKLW T P V + SL +L + YLDL+LIH P + FP D
Sbjct: 70 TIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFPMD 129
Query: 413 ADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN-QVE 586
+G D +DYVDTW+ +E LV GLVR++GVSNF Q+QR+LD P+ N QVE
Sbjct: 130 DNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVE 189
Query: 587 CHPYLNQKRLKQFCEDRDI 643
CHP+L Q L +FC+ + I
Sbjct: 190 CHPFLAQNELIEFCKKQGI 208
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 203 bits (495), Expect = 3e-51
Identities = 96/197 (48%), Positives = 129/197 (65%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+ GAK P +G+GTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G +K ++
Sbjct: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
VVKREDLFITSKLW T H P V AL +L++L ++Y+DLYLIHWP K+ +
Sbjct: 70 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
VD TWKA+E L G R++GVSNF++K+L +L+ A V P NQVECH
Sbjct: 130 -----NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECH 184
Query: 593 PYLNQKRLKQFCEDRDI 643
P Q +L++FC+ + +
Sbjct: 185 PSWRQTKLQEFCKSKGV 201
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 203 bits (495), Expect = 3e-51
Identities = 96/197 (48%), Positives = 129/197 (65%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+ GAK P +G+GTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G +K ++
Sbjct: 10 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 69
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
VVKREDLFITSKLW T H P V AL +L++L ++Y+DLYLIHWP K+ +
Sbjct: 70 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 129
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
VD TWKA+E L G R++GVSNF++K+L +L+ A V P NQVECH
Sbjct: 130 -----NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECH 184
Query: 593 PYLNQKRLKQFCEDRDI 643
P Q +L++FC+ + +
Sbjct: 185 PSWRQTKLQEFCKSKGV 201
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 199 bits (486), Expect = 4e-50
Identities = 93/186 (50%), Positives = 127/186 (68%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL++G+KIP +G+GTW+S+P + AVK A+ GYRHID A +YGNE EVG+ IK E
Sbjct: 17 TLADGSKIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK----E 72
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V R+D+++TSKLW H P+ V ALE +L++L +DYLD YLIHWP ++K + FP
Sbjct: 73 SGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPK 132
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
D DG + + +TWKA+E L+ G VR +G+SNFN L+RIL A VKP +Q+E
Sbjct: 133 DKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMEL 192
Query: 590 HPYLNQ 607
HP+L Q
Sbjct: 193 HPFLPQ 198
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 195 bits (475), Expect = 9e-49
Identities = 100/198 (50%), Positives = 132/198 (66%), Gaps = 5/198 (2%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
V TTL+ GA + ++G GTW++ PGEV Q VK AI+ GYRH+D A VY N+ EVG AIK
Sbjct: 2 VGTTTLNTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK- 60
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDD 394
E VKREDLFITSKLWN HRP+ V AL+ +L+ L ++YLDLYLIHWP A+ E D
Sbjct: 61 ---EAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGD 117
Query: 395 A---IFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 562
+FP D +++ +V VDTWKA+ L+ G V+++GVSNF++K + I++ V
Sbjct: 118 ITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGV 177
Query: 563 KPVTNQVECHPYLNQKRL 616
P NQ+E HP L Q L
Sbjct: 178 TPSVNQIERHPLLLQPEL 195
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 192 bits (469), Expect = 5e-48
Identities = 89/197 (45%), Positives = 129/197 (65%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+ G IP IG GTW+ + + AV A+ GYRHID A VYG EK +G A+
Sbjct: 10 LNTGEDIPAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGRALA----RS 64
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
+ R++LFITSKLWN HRP+ V A++ SL+NL IDYLDLYL+HWP A+ D +FP D
Sbjct: 65 RLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDMFPKD 124
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
+ G + D+DYVDT+KA+E LV G +++G+SNF+ +++R+L++ S+ P Q+E H
Sbjct: 125 SQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCSIVPAVMQMELH 184
Query: 593 PYLNQKRLKQFCEDRDI 643
P+L Q ++ + + I
Sbjct: 185 PWLQQNDFVEWLKSKGI 201
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 191 bits (465), Expect = 1e-47
Identities = 89/206 (43%), Positives = 134/206 (65%)
Frame = +2
Query: 26 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE 205
++ ++ +LSNG ++P++G+GT KS+ +V ++V++AI IGYRHIDCA +YGNE+EVG+
Sbjct: 15 VIPTMQYASLSNGDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDCASIYGNEEEVGD 74
Query: 206 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
AI+ IQ + R +L+ITSKLW+ H + V AL SL+NL +DYL+LYLIHWP +
Sbjct: 75 AIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIR 134
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
+ F D + + +TW+A+E GL + +GVSNF K+LQ+++ + K
Sbjct: 135 PEKT-FAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQK 193
Query: 566 PVTNQVECHPYLNQKRLKQFCEDRDI 643
P NQVE HP L Q L ++C +I
Sbjct: 194 PEVNQVEHHPLLQQPTLIEYCASEEI 219
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 190 bits (463), Expect = 2e-47
Identities = 95/203 (46%), Positives = 135/203 (66%), Gaps = 6/203 (2%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSK-PGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L++G +IP IG+GT+ S+ PGEV A+ +A+ GYRHID A YGNEK +G ++K +E
Sbjct: 19 LNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKE 78
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G +KRED+F TSKLWN+ H +LV ++ +L I YLDLYLIHWP A++ + + T
Sbjct: 79 GEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLT 138
Query: 410 -----DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
D +G + V +TW+ +E LV GLV+S+GVSNFN + L +L A +KPV
Sbjct: 139 IEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVV 198
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQVE HPYL Q +L+++C+ +I
Sbjct: 199 NQVEIHPYLTQFKLQEYCDKYEI 221
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 190 bits (462), Expect = 3e-47
Identities = 96/210 (45%), Positives = 133/210 (63%), Gaps = 10/210 (4%)
Frame = +2
Query: 44 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
+ TL+NG K+P++G+G WK + +AI +GYR D A YGNEKEVGE I+ I
Sbjct: 4 LVTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAI 63
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK------ 385
EG+V R+D+F+ SKLWN FH PD V+ AL+ +L ++ +DYLDLY IH+P A+K
Sbjct: 64 SEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE 123
Query: 386 EDDAIFPTDAD----GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
+ F T AD G I + V +DT++ALE V GL++S+GVSNF +Q +L
Sbjct: 124 KYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRG 183
Query: 554 ASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
+KPV Q+E HPYL Q+ L +FC+ DI
Sbjct: 184 CRIKPVALQIEHHPYLTQEHLVEFCKLHDI 213
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 189 bits (461), Expect = 4e-47
Identities = 95/198 (47%), Positives = 129/198 (65%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+NG KIP +G+GTW S GEV +AV+ AI GYRHIDCA YGNEKEVG+ IK+ I +
Sbjct: 6 TLNNGYKIPKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAIAK 65
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G VKRE+LF+T+KLW+T + VR A SL+ L ++YLDLY+IH P + F
Sbjct: 66 GYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTADKKTGEFTE 125
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+ + +TW+ +E LV GLV+S+GVSNFN K+L+ +L A ++P NQ E
Sbjct: 126 EI--------IPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEF 177
Query: 590 HPYLNQKRLKQFCEDRDI 643
H Y + +L QFC+ +I
Sbjct: 178 HIYYQRPKLHQFCKKHNI 195
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 189 bits (461), Expect = 4e-47
Identities = 93/192 (48%), Positives = 127/192 (66%), Gaps = 21/192 (10%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRED 250
IP +G+ +WK+ PG+VT+AVK+AID GYRH DCA+ Y NE+EVG I+ KI+EG V+RED
Sbjct: 4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63
Query: 251 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---------DDAIF 403
LFI +KLW T H+ LV A SL+ L ++YLDLYLIHWP +K + F
Sbjct: 64 LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123
Query: 404 ----------PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
P D + SD D++DTW+A+E LV GLV+++GVSNFN +QL+R+L+
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
Query: 554 ASV--KPVTNQV 583
+ KP+TNQ+
Sbjct: 184 PGLRFKPLTNQI 195
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 189 bits (460), Expect = 6e-47
Identities = 93/199 (46%), Positives = 127/199 (63%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+ G +P +G+GTW+SK EV AV A+ GYRHID A VYGNE+EVG+ ++
Sbjct: 9 LNTGYDMPAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGMRLS---- 64
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-EDDAIFP- 406
V RE++F+TSKLWNT H P+ V A++ SL +L DYLDLYLIHWP A++ I P
Sbjct: 65 GVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQPV 124
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
+ G I DV DTW A+E LV G VRS+GVSNF ++++ +L A + P NQ+E
Sbjct: 125 NEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITPAVNQIE 184
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HP+L Q+ L ++ + I
Sbjct: 185 AHPFLQQRDLLEWSTQKGI 203
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 188 bits (459), Expect = 8e-47
Identities = 90/198 (45%), Positives = 123/198 (62%), Gaps = 2/198 (1%)
Frame = +2
Query: 56 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGV 235
+NG +IP +G+GTWK++P EV AV+DA+ GY H+DCA Y NE EVGEA++ + G
Sbjct: 11 ANGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREAFERGD 70
Query: 236 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 415
KRED+F+TSKLWN RP VR AL +L +L + YLDLYLIHWP A+K + P DA
Sbjct: 71 AKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKRGTVLQP-DA 129
Query: 416 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN--ASVKPVTNQVEC 589
+ I + W LE V GLVR +GVSNFN QL + D+ ++P NQ+E
Sbjct: 130 EASI-------AECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIES 182
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP + L ++ + + +
Sbjct: 183 HPLWSNDSLVKYSQSKGL 200
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 188 bits (458), Expect = 1e-46
Identities = 87/194 (44%), Positives = 125/194 (64%), Gaps = 4/194 (2%)
Frame = +2
Query: 74 PVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGV--VKRE 247
P +G GTW++ P V AV+ A+ GYRHIDCA+VY NE+ +G A ++ +KRE
Sbjct: 5 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64
Query: 248 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA--IFPTDADG 421
D++ITSKLWN HRP+LVR + ++ +L +DYLDL+L+HWP A+ +D +FP DA+G
Sbjct: 65 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 124
Query: 422 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYL 601
+ V DTW+A+E LV GLV+ +GVSN+ L +L+ A +KP+ NQ+E HP+
Sbjct: 125 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWH 184
Query: 602 NQKRLKQFCEDRDI 643
+FC D I
Sbjct: 185 PNDATVKFCLDNGI 198
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 188 bits (457), Expect = 1e-46
Identities = 91/202 (45%), Positives = 125/202 (61%), Gaps = 2/202 (0%)
Frame = +2
Query: 44 VTTLS--NGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
+TTL +G IP IG+GTWKS P +V +AVK A++ GY+HIDCA Y NE VGEA K
Sbjct: 1 MTTLKFRDGDSIPSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKE 60
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
+ G VKRED+F+TSKLWN H+ + V AL+ +L++LN+DYLDLYL+HWP A+K
Sbjct: 61 SFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVN 120
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
FP + + + +T A+ GL++ +GVSNF+ ++L+ + P N
Sbjct: 121 GFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMN 180
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVE HPYL Q L +C I
Sbjct: 181 QVELHPYLPQNDLYSYCSKEGI 202
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 186 bits (453), Expect = 4e-46
Identities = 89/198 (44%), Positives = 120/198 (60%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG +IP +G+GTW + V + A+++A+ +GYRHID AF+YGNEK +G +K E
Sbjct: 8 LNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDE 67
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
GVV+R+DLFITSKLWNTFH L SL +L +DY+DLYLIHWP +
Sbjct: 68 GVVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVE 125
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
K D V WK +E LV GL +S+G+SNF ++IL + P Q+E
Sbjct: 126 SCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIEL 185
Query: 590 HPYLNQKRLKQFCEDRDI 643
HPYLNQK L +F + + I
Sbjct: 186 HPYLNQKELVEFMKSKGI 203
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 184 bits (449), Expect = 1e-45
Identities = 93/202 (46%), Positives = 129/202 (63%), Gaps = 4/202 (1%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+ GAKIP G+GTW+ G + +AV AI GYR ID A+VYGNE+EVG+ I+ I
Sbjct: 7 TLNTGAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISS 66
Query: 230 GVVKREDLFITSKLWNTF-HRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED--DAI 400
G+VKREDLF+ SK W T+ R +L L+ SL+ L +DY+DLYL+HWP + D
Sbjct: 67 GIVKREDLFVVSKCWATYTTRCEL---GLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEK 123
Query: 401 FPTDADGKIQFSDV-DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
FP ADG ++VDTWK +E L G +++GVSN++ L+++L +A+ P N
Sbjct: 124 FPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVPAVN 183
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVE HP L Q+ L FC+++ I
Sbjct: 184 QVENHPQLPQQELVDFCKEKGI 205
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 184 bits (449), Expect = 1e-45
Identities = 90/199 (45%), Positives = 126/199 (63%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L++G IP IG+GTW SKP EV AV+ A+ GYRHID A Y NE EVG K +
Sbjct: 9 LNSGYNIPAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGWK----KS 64
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAIFPT 409
V R+ +FITSKLWNT H P+ V A+ +L++L DYLDLYLIHWP A++ ++ + P
Sbjct: 65 GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTPI 124
Query: 410 D-ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
D + + ++V DTW ALE LV +RS+G+SNF ++ +L A + P NQ+E
Sbjct: 125 DPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIPPAVNQIE 184
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HPYL Q L ++ ++++I
Sbjct: 185 AHPYLQQPGLHKYLKEKNI 203
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 184 bits (447), Expect = 2e-45
Identities = 85/175 (48%), Positives = 118/175 (67%), Gaps = 1/175 (0%)
Frame = +2
Query: 122 QAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLV 301
+A + AI GYRHID AF Y NE +VG AI+ KIQ+G+++R+D+FI SKLW T H P+ +
Sbjct: 4 RACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDI 63
Query: 302 RGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAIFPTDADGKIQFSDVDYVDTWKALEPL 478
SL +L +DYLD YL+H+P K+ D +FP + DGKI +D+DYVD W+ +E L
Sbjct: 64 PVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEAL 122
Query: 479 VCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
G V+S+GVSNF +Q+ R+L A + P NQVE HPYL Q L +C+ ++I
Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNI 177
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 182 bits (443), Expect = 7e-45
Identities = 82/210 (39%), Positives = 133/210 (63%), Gaps = 5/210 (2%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M TL++G ++PVIG GTW+ + V+DA++ GYRHID A + N++EV
Sbjct: 1 MPIADTVTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAG 60
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
IK + V+RE+LF++SK+WNT+H + ++ L Y+DL +IHWP + E
Sbjct: 61 IKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAE 120
Query: 389 DD-----AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
D+ ++P A+GK+++SDVDY++TWKALE G +RS+G++NFN Q++++
Sbjct: 121 DEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTK 180
Query: 554 ASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
+KP QVE +P+L+Q+ ++QFC ++ I
Sbjct: 181 GLIKPAVLQVEMNPFLDQEEIRQFCREKGI 210
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 181 bits (441), Expect = 1e-44
Identities = 87/207 (42%), Positives = 127/207 (61%), Gaps = 2/207 (0%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M + T +NG K+PVIGIGTW++ E+ A+ A++ GYRHID A VYGNEK +G
Sbjct: 1 MVNTKFLTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRV 60
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK- 385
+K + G VKRE+LFI +K+ +RP V ++ SL +L +DY+DLYL+H P
Sbjct: 61 LKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTINI 120
Query: 386 EDDAIFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 562
+D F D +G ++ ++ W A+E LV GL +S+GVSNF+ Q+ R+L N +
Sbjct: 121 NEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKI 180
Query: 563 KPVTNQVECHPYLNQKRLKQFCEDRDI 643
+P NQ+E H YL Q+ L FC+ +I
Sbjct: 181 RPANNQIEHHVYLQQRDLVDFCKSENI 207
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 181 bits (440), Expect = 2e-44
Identities = 89/205 (43%), Positives = 126/205 (61%), Gaps = 7/205 (3%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL++GA+IP +G GTW+S PG+V AV +A+ GYRH+D A +Y N++EV E IK ++
Sbjct: 8 TLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYKD 67
Query: 230 GV-VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
+KRED+FITSKLWN+ H P +V AL+ L L +DYLDLYL+HWP ++ +FP
Sbjct: 68 VPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELFP 127
Query: 407 TDADGKIQFSDV------DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
D ++ DV VDTWKA+ L R++GVSN L+ I++ V P
Sbjct: 128 LVKDSSVEGGDVVINDDISIVDTWKAMTQLP-KSKARTVGVSNHMIPHLEAIINATGVVP 186
Query: 569 VTNQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HP L L ++C+ + I
Sbjct: 187 AVNQIERHPVLQSNELIEYCQKKGI 211
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 180 bits (438), Expect = 3e-44
Identities = 91/198 (45%), Positives = 128/198 (64%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
LS+G +IP +G+GT K E+ A+ A++ GYRHID AF Y NE +G+ +K +G
Sbjct: 28 LSSGHEIPAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKKWFDKG 87
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT- 409
KRED+FITSKL + +RP V L+ SL++L +DY+D+YLIH P A KE + +
Sbjct: 88 G-KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQ 146
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
D DG F DVD+ WKA+E V G +S+G+SNFN Q+ I +NA +KP QVE
Sbjct: 147 DKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIKPSNLQVET 206
Query: 590 HPYLNQKRLKQFCEDRDI 643
H YL QK+L++FC++ +I
Sbjct: 207 HAYLQQKQLRKFCKEHNI 224
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 178 bits (434), Expect = 8e-44
Identities = 87/205 (42%), Positives = 132/205 (64%), Gaps = 2/205 (0%)
Frame = +2
Query: 23 LIMTSVPVTTLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIDCAFVYGNEKEV 199
+ + S+P+ T GA++P+ G+GTW+ K E+T A++ A+D GYR ID A +Y NE +
Sbjct: 1 MTVDSIPLNT---GAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHII 57
Query: 200 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 379
G+ + I G +KRED+F+TSKL T H P+ V +E L+ L ++Y+DLYLIH P
Sbjct: 58 GKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFP 117
Query: 380 YKEDDAIF-PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 556
+K + F P +G++ +++ ++DTW+ALE L G +++LGVSNF+ QLQ + D A
Sbjct: 118 FKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAA 177
Query: 557 SVKPVTNQVECHPYLNQKRLKQFCE 631
VKP QVECH Y Q+ L+ C+
Sbjct: 178 EVKPANQQVECHIYWPQQELRALCK 202
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 176 bits (429), Expect = 3e-43
Identities = 88/198 (44%), Positives = 125/198 (63%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+ AKIP IG+GTW+S +AVK A+ GYR IDCA +YGNE EVGEA+ + G
Sbjct: 14 LNTKAKIPAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEAL-AEAFNG 72
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
+KRED+F+TSKL+ T + + + ++ VSL+NL + YLDLYL+HWP DA P
Sbjct: 73 SLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPS 132
Query: 413 ADGKIQFSDVDYV-DTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
G ++ + WKA+E L+ GLVR++GVSNF +Q++ +L A + P NQV+
Sbjct: 133 NSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKL 192
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP+ Q L +FC+ + I
Sbjct: 193 HPFWRQDELVKFCQSKGI 210
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 176 bits (428), Expect = 4e-43
Identities = 84/174 (48%), Positives = 119/174 (68%), Gaps = 2/174 (1%)
Frame = +2
Query: 113 EVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRP 292
+ + AV AI+ G+RH D A+ Y NEKE+GEA++T+I+ G + RE++F+T+KLWNT H P
Sbjct: 45 QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104
Query: 293 DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--DDAIFPTDADGKIQFSDVDYVDTWKA 466
VR E L L Y+DLYL+H+P YK D+ + P D ++Q ++DY+DTW+A
Sbjct: 105 RDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGD-ELQTVEIDYLDTWRA 163
Query: 467 LEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQKRLKQFC 628
+E LV G+VRS+G+SNFN +Q+QRI+ +S KPV NQVE P QK L +C
Sbjct: 164 MENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYC 217
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 176 bits (428), Expect = 4e-43
Identities = 90/199 (45%), Positives = 126/199 (63%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+NG IP IG+GT+K + A+K A++ GYR ID AFVY NE+ VG+A++ +G
Sbjct: 4 LNNGHSIPPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQG 63
Query: 233 V-VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+ RED+FI SKL TFHRP+ V +SL L +DY+DLYL+H P A ++
Sbjct: 64 NDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSG----- 118
Query: 410 DADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
D + + + D V ++TWKALE GLVRS+GVSNFN +QL I+ + S++PV NQVE
Sbjct: 119 DGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVE 178
Query: 587 CHPYLNQKRLKQFCEDRDI 643
C +Q +L++FC I
Sbjct: 179 CSIGFHQVKLRKFCNREGI 197
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 176 bits (428), Expect = 4e-43
Identities = 88/205 (42%), Positives = 129/205 (62%), Gaps = 7/205 (3%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSK--PGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
TL+ GAKIP +G GT+ ++ GE AV A+D+GYRH+DCA+ Y NE EVG+AI+ +
Sbjct: 16 TLNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIRDFL 75
Query: 224 -QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP-QAYKEDDA 397
+ V R+DLFI +K+WN H P+ V+ + + S NL +DY+DL+L+HWP A K D
Sbjct: 76 ARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKNADR 135
Query: 398 IFPTDADGKIQFSDV---DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
DGK + + TW+A+E LV G+V+++GVSN+ L+++L+ A +KP
Sbjct: 136 TVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFARIKP 195
Query: 569 VTNQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HP+L L +FC DI
Sbjct: 196 AVNQIEIHPFLPNTELVEFCFQNDI 220
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 176 bits (428), Expect = 4e-43
Identities = 96/218 (44%), Positives = 131/218 (60%), Gaps = 4/218 (1%)
Frame = +2
Query: 2 HSQV*SNLIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIDCAFV 178
H Q+ MTS+ T L+NG IP IG+GTWKS EV AV+ A+ + GYRHID AF
Sbjct: 20 HIQITHKHTMTSLDFT-LNNGKTIPAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFN 78
Query: 179 YGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLY 358
Y NE VG IK +++GV KRED+F+T+K+W T+H D V L++SL L +DY+D+
Sbjct: 79 YRNEDAVGLGIKRAMEKGV-KREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDML 135
Query: 359 LIHWPQAYKED--DAIFPTDADGKIQFSDV-DYVDTWKALEPLVCHGLVRSLGVSNFNSK 529
LIHWP + D ++P DG + TWK +E ++ G +S+GVSNF+
Sbjct: 136 LIHWPVPLNPNGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIP 195
Query: 530 QLQRILDNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
L+ +L A V P NQVE HP L Q L +FC+ +I
Sbjct: 196 YLEELLKEAEVVPAVNQVELHPLLPQLELMEFCKKNNI 233
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 175 bits (427), Expect = 6e-43
Identities = 85/183 (46%), Positives = 117/183 (63%)
Frame = +2
Query: 95 WKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLW 274
W SKPG+V AVK AID GYRHIDCA VYGNE EVG +K K VVKRED+FITSKLW
Sbjct: 5 WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64
Query: 275 NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVD 454
N H PD V A +++L+NL + Y+DLYL+HWP AY
Sbjct: 65 NNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAY------------------------ 100
Query: 455 TWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQKRLKQFCED 634
+A+E LV G +++G+SNF+ K ++R+++ A+++P QVE HP L Q++L +FC++
Sbjct: 101 --QAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKE 158
Query: 635 RDI 643
++
Sbjct: 159 HNM 161
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 175 bits (426), Expect = 8e-43
Identities = 88/199 (44%), Positives = 122/199 (61%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGA-KIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L +GA IP +G GT + P A +DA+ G+RH DCA Y NE+EVGEA++
Sbjct: 13 LHHGAGHIPALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAA 72
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G + RE++F+T+KLWNT HRP+ V A E SL L +DYLDLYLIH P A++ D P
Sbjct: 73 GNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPR 132
Query: 410 DADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
D +G + + + V +TW ALE LV G R++G+S+ + +L I + A +KP QVE
Sbjct: 133 DQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVE 192
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HPYL + L +FC+ I
Sbjct: 193 SHPYLPETELLEFCKRNGI 211
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 174 bits (423), Expect = 2e-42
Identities = 97/190 (51%), Positives = 121/190 (63%), Gaps = 8/190 (4%)
Frame = +2
Query: 98 KSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSK--- 268
KS G+V +AVK AID GYRHIDCA+VY NE EVGEAI+ KIQE VKREDLFI SK
Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101
Query: 269 ---LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSD 439
LW TF LVR A E +L++L + YLD+YLIHWPQ +K
Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK------------------ 143
Query: 440 VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV--KPVTNQVECHPYLNQKR 613
A+E LV GLV++LG+SNFN Q++++L+ + KPVTNQVECHPYL Q++
Sbjct: 144 --------AMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK 195
Query: 614 LKQFCEDRDI 643
L Q+C + I
Sbjct: 196 LIQYCHSKGI 205
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 173 bits (421), Expect = 3e-42
Identities = 86/211 (40%), Positives = 127/211 (60%), Gaps = 9/211 (4%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTW---------KSKPGEVTQAVKDAIDIGYRHIDCAFVYGNE 190
VP+ + N ++P I +GT+ SK ++ V AID+GYRH D A +Y E
Sbjct: 22 VPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTE 81
Query: 191 KEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 370
EVGEAI+ KI EGV+KRED+F+T+KLWNT H+ + V A++ +L +DY+DL+L+HW
Sbjct: 82 AEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHW 141
Query: 371 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 550
P A ED S+ DY++TW+A E +V G +S+G+SNFN Q+ +L
Sbjct: 142 PIALNED-----------YSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQ 190
Query: 551 NASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
++KPV Q+E HP + Q+ L + +D I
Sbjct: 191 ECTIKPVALQIEVHPQIIQEDLITYAKDEGI 221
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 172 bits (419), Expect = 5e-42
Identities = 85/198 (42%), Positives = 128/198 (64%), Gaps = 6/198 (3%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+NGA+IP +G GTWK + T AV AI GYRHIDCA+ Y NE +A+ I++
Sbjct: 13 TLANGAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKK 68
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDDAIFP 406
V R L++TSKLWN+FH P+ V AL+ SL++L DYLDLYL+HWP A+ ++ P
Sbjct: 69 AGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVP 128
Query: 407 ---TDADGKIQFSDV--DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
+ ++ D+ D++ T++ +E +V G VR++GVSNFN ++ ++D AS+KPV
Sbjct: 129 SIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPV 188
Query: 572 TNQVECHPYLNQKRLKQF 625
NQVE + ++ + L+ +
Sbjct: 189 VNQVEVNLGVHNEELRNY 206
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 172 bits (418), Expect = 7e-42
Identities = 87/198 (43%), Positives = 123/198 (62%), Gaps = 6/198 (3%)
Frame = +2
Query: 68 KIPVIGIGTWKSK-PGEVTQAVKDAID-IGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVK 241
+IP +G GT+ + P ++ A+ AI+ G RHID AF Y N+ +GE +K +G +K
Sbjct: 2 EIPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIK 61
Query: 242 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK----EDDAIFPT 409
RED+FIT+KLW T HR DLV L +L L + Y+DL+LIH P A+K +D + P
Sbjct: 62 REDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPK 121
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
D GKIQ+ +D ++T+ A+E GL R +GVSNF+ +QL+RI N +KP NQVEC
Sbjct: 122 DEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVEC 181
Query: 590 HPYLNQKRLKQFCEDRDI 643
+ Y K L +CE +I
Sbjct: 182 NIYRQFKPLLSYCESHNI 199
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 171 bits (417), Expect = 9e-42
Identities = 87/195 (44%), Positives = 127/195 (65%), Gaps = 6/195 (3%)
Frame = +2
Query: 71 IPVIGIGTWKSK-PGEVTQAVKDAI-DIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKR 244
IP IG+GT+ ++ P + AV AI D GYRH+DCA Y N++ +GEA+ +G VKR
Sbjct: 4 IPSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKR 63
Query: 245 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY--KEDDAIFPTDAD 418
E+++ITSK+WNT HRPDL+ ++ +L+ L ++YLDL L+HW A+ +EDD P D
Sbjct: 64 EEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDET 123
Query: 419 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVECH 592
GKI ++D ++TWKA+E GL + +GVSNF+ +QL+R+ + VK P NQVE H
Sbjct: 124 GKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESH 183
Query: 593 PYLNQKRLKQFCEDR 637
YL Q+ + + R
Sbjct: 184 MYLQQQPMLDYLTQR 198
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 171 bits (415), Expect = 2e-41
Identities = 92/217 (42%), Positives = 128/217 (58%), Gaps = 22/217 (10%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
LS+G +P +G+GTW SKP EV AV+ A+ +GYRHID A Y NE EVG K +
Sbjct: 9 LSSGYDMPAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNGWK----KS 64
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYL----------------- 361
V R+ +FITSKLWNT H PD V A+ +L++L DYLDLYL
Sbjct: 65 GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIHDLLSLLT 124
Query: 362 ---IHWPQAYKE-DDAIFPTDADGK-IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNS 526
IHWP A++ ++ + P D K + +++ DTW ALE LV G VRS+GVSNF
Sbjct: 125 NNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTI 184
Query: 527 KQLQRILDNASVKPVTNQVECHPYLNQKRLKQFCEDR 637
++++ +L A + P NQ+E HPYL Q L ++ +++
Sbjct: 185 EKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEK 221
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 170 bits (414), Expect = 2e-41
Identities = 87/203 (42%), Positives = 130/203 (64%), Gaps = 6/203 (2%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L++G IP +G+GT + G V + V AI GYRHID AF+YG+E +VG+ IK I E
Sbjct: 9 LNDGHSIPALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGIKRAIDEE 66
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD----AI 400
+VKRE+LF+T+K+W TF+ + V +L++SL++L++DY+DL L+HWP + D AI
Sbjct: 67 LVKRENLFVTTKVWPTFY--NRVSESLDISLKDLSLDYVDLLLVHWPVSLLADSDDPRAI 124
Query: 401 FPTDADGKIQFSDV--DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
+ + DG +++SD D++ T+K +E G +S+GVSN + L+R+LD P
Sbjct: 125 YLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQVKTVPAV 184
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQ E HPYL QK+ +F E I
Sbjct: 185 NQFEIHPYLPQKKEIEFNEKHGI 207
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 170 bits (413), Expect = 3e-41
Identities = 88/212 (41%), Positives = 125/212 (58%), Gaps = 3/212 (1%)
Frame = +2
Query: 17 SNLIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKE 196
++LIM++ L+ GA IP IG+GTW++K GEV QAV A+ GYRHID A Y NE E
Sbjct: 29 NSLIMSAPTSFKLNTGASIPAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDE 88
Query: 197 VGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP- 373
VG IK + V R ++F+TSK+W+++H D V L+ +L++L DYLDLYLIHWP
Sbjct: 89 VGLGIK----DSGVPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQTDYLDLYLIHWPV 142
Query: 374 -QAYKEDDAIFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 547
A +FP DG D D TW +E ++ G +++G+SN ++ I+
Sbjct: 143 RLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHII 202
Query: 548 DNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
V P NQVE HPY Q L ++C+++ I
Sbjct: 203 KTGKVTPAVNQVELHPYCPQHALLKYCKEKGI 234
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 170 bits (413), Expect = 3e-41
Identities = 87/208 (41%), Positives = 123/208 (59%), Gaps = 5/208 (2%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
+ P T L++G +P++G G WK + AI GYR D A YGNE E G+ +
Sbjct: 2 TTPSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVA 61
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK-ED 391
IQEG+VKREDLFI SKLWN+FH D V L + +DY DL+++H+P A K D
Sbjct: 62 RAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVD 121
Query: 392 DAI-FP---TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 559
A+ +P + K++FS+ +TW A+E LV L RS+GVSNF+++ L +L A
Sbjct: 122 PAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYAR 181
Query: 560 VKPVTNQVECHPYLNQKRLKQFCEDRDI 643
++P T Q+E HPYL Q+RL + + I
Sbjct: 182 IRPATLQIEHHPYLTQERLVTYAQKEGI 209
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 169 bits (410), Expect = 7e-41
Identities = 92/199 (46%), Positives = 118/199 (59%)
Frame = +2
Query: 47 TTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQ 226
T LSNG IP++G GT+ +V A+K A+D GYRH+DCA +YGNE VGEAIK
Sbjct: 4 TQLSNGVTIPMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEAIKA--- 60
Query: 227 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
+ R DLFITSK+WN D A + +L +L +DYLDLYLIHWP EDD
Sbjct: 61 -SGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---NEDDFELT 116
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
+DTW+ LE L VR++GVSNF+ QL+++ + A+VKP+ NQ+E
Sbjct: 117 --------------LDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIE 162
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HPY Q L QF D DI
Sbjct: 163 RHPYKVQADLGQFDTDNDI 181
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 168 bits (409), Expect = 9e-41
Identities = 86/208 (41%), Positives = 132/208 (63%), Gaps = 5/208 (2%)
Frame = +2
Query: 35 SVPVTTLSNGA-KIPVIGIGTWKSKPGE---VTQAVKDAIDIGYRHIDCAFVYGNEKEVG 202
++P LS+G K+PV+G+GT P + V +AV +A+ +GYRH D A +Y +E+ +G
Sbjct: 4 TIPEVPLSSGGRKMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPLG 63
Query: 203 EAIKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 379
+AI + EG++K R++LFITSKLW + + V AL+ +L+NL ++Y+D+YLIHWP +
Sbjct: 64 DAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVS 123
Query: 380 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 559
K + +P K F +DY W+A+E GL +++GVSNF+ K+L +L NA
Sbjct: 124 SKPGNYEYPIK---KEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLANAK 180
Query: 560 VKPVTNQVECHPYLNQKRLKQFCEDRDI 643
V P NQVE +P QK+L +FC+ I
Sbjct: 181 VPPAVNQVEVNPCWQQKQLTEFCKSNGI 208
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 168 bits (408), Expect = 1e-40
Identities = 85/191 (44%), Positives = 120/191 (62%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRED 250
IP G+GTW + G V AV+ A+ GYRHID A ++ NE EVG+ IK V R++
Sbjct: 60 IPAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKGIKAS----GVSRDE 115
Query: 251 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 430
+++T KLWNT HRP+LVR A+E S+ NL ++YLDLYLIH+P A+ + D D
Sbjct: 116 IWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPE----TRDVD---- 167
Query: 431 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQK 610
++ +DTWKA+E LV GL R++G SNF K + +IL AS++P ++ E HPYL Q+
Sbjct: 168 -NNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEFETHPYLQQQ 226
Query: 611 RLKQFCEDRDI 643
F + +I
Sbjct: 227 SFVDFHKKENI 237
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 167 bits (405), Expect = 3e-40
Identities = 86/207 (41%), Positives = 123/207 (59%), Gaps = 5/207 (2%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSK---PGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
+P TL++GA++P IG+GT+ S PGEV +V A ++GYRH DCA VY NE+E+G
Sbjct: 16 IPQRTLASGARMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGAT 75
Query: 209 IKTKIQEGV-VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP-QAY 382
+ + ++REDL+ITSKLWN H V A E SLR+L +DYLDLYLIHWP +
Sbjct: 76 FRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPNF 135
Query: 383 KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 562
+ + + +++ TW+ LE L GLVR +G SN +LQ +L +A V
Sbjct: 136 HPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDARV 195
Query: 563 KPVTNQVECHPYLNQKRLKQFCEDRDI 643
+P N++E HP+ Q L + R+I
Sbjct: 196 RPAVNEMELHPHFQQPALFDYVRVRNI 222
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 166 bits (403), Expect = 5e-40
Identities = 88/198 (44%), Positives = 126/198 (63%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE-AIKTKIQE 229
L+NG +P IG+GTW + PGEV +AV A++ GYR IDCA Y NEKE+GE I+ ++
Sbjct: 8 LNNGKFMPAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKN 67
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
RE+LF+TSKLW + +R + S+++L YLDLYLIHWP A K D + P
Sbjct: 68 H--PREELFVTSKLW--MDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPK 123
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
D F D+D + W+ +E LV GLV+S+G+SNF Q+++I+ +KPV NQVE
Sbjct: 124 PED----FLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVEL 179
Query: 590 HPYLNQKRLKQFCEDRDI 643
+ YL Q +L++ C+ +I
Sbjct: 180 NVYLQQNKLREVCKSYNI 197
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 166 bits (403), Expect = 5e-40
Identities = 84/202 (41%), Positives = 124/202 (61%), Gaps = 9/202 (4%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
VP +S+ + +P +G+G WK QAV +AI +GYRH+D A YGNE++VGE I
Sbjct: 7 VPGVKVSSKS-MPAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIAR 65
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA--YKED 391
I EG+ RE+L+IT+KLWNT+HR + V A S+ +L +DY+DLYL+H+P A Y +
Sbjct: 66 AIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRYVDF 125
Query: 392 DAIFPTD-------ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 550
+ +P + D ++ V +TW A+E LV GLVR +GV N+++ L ++
Sbjct: 126 NDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLLHDLMS 185
Query: 551 NASVKPVTNQVECHPYLNQKRL 616
A +KP Q+E HPYL Q+ L
Sbjct: 186 YARIKPAMLQIESHPYLTQEAL 207
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 166 bits (403), Expect = 5e-40
Identities = 85/199 (42%), Positives = 121/199 (60%), Gaps = 1/199 (0%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
T NG +P +G GTW++ EV +A+ +A++ GYRHID A VY NEK +G+ +K +
Sbjct: 8 TFENGTTMPALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMDA 67
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G V R++LFI +KL R V L+ SL +L ++Y+DLY +H P E D F
Sbjct: 68 GKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFLV 127
Query: 410 DADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
+ DG I + D+V WKA+E + GL R++G+SNFN +Q+QRILDN +KP Q+E
Sbjct: 128 E-DGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIE 186
Query: 587 CHPYLNQKRLKQFCEDRDI 643
H YL Q L +FC+ I
Sbjct: 187 NHIYLQQPELVKFCKANGI 205
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 165 bits (402), Expect = 6e-40
Identities = 90/202 (44%), Positives = 127/202 (62%), Gaps = 10/202 (4%)
Frame = +2
Query: 68 KIPVIGIGTWKSKPGE-----VTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
+IP IG+GTWKS E +T A+K+A GY HIDCA Y NE VG+A++ G
Sbjct: 3 RIPTIGLGTWKSPRSEDLVNAITYAIKEA---GYVHIDCALCYENEDIVGQALQQCWDSG 59
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE---DDAIF 403
+ KRE+++ITSKLWNT HR ++V A +L++L +DYLDLYL+H+P A++ ++
Sbjct: 60 I-KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLN 118
Query: 404 PTDADGKIQFSD-VDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI-LDNASVKPVTN 577
P D G F D V +DTWKA+E LV GLV+ +GVSN+ QL+R+ +A P TN
Sbjct: 119 PLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTN 178
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVE + Y+ Q L+++ I
Sbjct: 179 QVEFNLYMQQGPLREYMHKEGI 200
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 164 bits (399), Expect = 1e-39
Identities = 83/210 (39%), Positives = 129/210 (61%), Gaps = 3/210 (1%)
Frame = +2
Query: 23 LIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVG 202
+I + LS+G +P+IG+GTW+ P + AV A++ GYRHID AF YGNE+ +G
Sbjct: 20 VITSGYKTIKLSSGHDMPMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIG 79
Query: 203 EAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY 382
+ +K +G KREDLFIT+KL R + V L++SL L ++Y+++YLIH P A+
Sbjct: 80 KTLKKWFDKG-GKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAF 138
Query: 383 KEDDAIF--PTDADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
+D + + DG + +D D+V W+A+E V G VRS+G+SNFN QL + ++
Sbjct: 139 VKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEH 198
Query: 554 ASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
A +KP Q+E Y Q+ +++ C +R+I
Sbjct: 199 AEIKPSNLQIELQAYNQQRPMRELCAERNI 228
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 163 bits (396), Expect = 3e-39
Identities = 82/206 (39%), Positives = 127/206 (61%), Gaps = 4/206 (1%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTW-KSKPGE--VTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
+P L++G K+PVIG+GT +S+P + DAI +GYRH D A VYG E+ +G A
Sbjct: 6 IPEVLLNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMA 65
Query: 209 IKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
+ I++G++K R+++FITSK WNT DL+ AL+ +L+ L ++Y+DLYLIHWP +
Sbjct: 66 VSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRLR 125
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
D + K D TWKA+E GL +S+G+ N+ +K+L ++L+ A++
Sbjct: 126 HD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIP 183
Query: 566 PVTNQVECHPYLNQKRLKQFCEDRDI 643
P NQVE +P Q L++FC+ + I
Sbjct: 184 PAVNQVEMNPSWQQGNLREFCKQKGI 209
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 163 bits (395), Expect = 4e-39
Identities = 93/212 (43%), Positives = 128/212 (60%), Gaps = 14/212 (6%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWK--SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
+L+NG +IP +G+GT K E QAVK AI GYRHID A+ Y E VGEAIK +
Sbjct: 26 SLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY---KEDD 394
++G +KREDLFIT+K+W D V +L SL+ L ++Y+DL L HWP + K+
Sbjct: 86 EDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143
Query: 395 AI-----FPTDADGKIQF-SDVDYVDTWKALEPLVC---HGLVRSLGVSNFNSKQLQRIL 547
I P D GK + +D DY++T+K LE + VR++GVSNF+ + L+R++
Sbjct: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203
Query: 548 DNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
VKP NQVE HP+L Q L++FC DI
Sbjct: 204 KECRVKPTVNQVETHPHLPQMELRKFCFMHDI 235
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 162 bits (393), Expect = 8e-39
Identities = 79/194 (40%), Positives = 125/194 (64%), Gaps = 2/194 (1%)
Frame = +2
Query: 68 KIPVIGIGTWK--SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVK 241
++PV+G+G+ + + +A+ +A+ GYRH D A YG+E+ +GEA+K I G+V
Sbjct: 20 RMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVS 79
Query: 242 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 421
R+DLF+TSKLW T + P LV AL SL+ L ++YLDLYLIHWP + + FP + +
Sbjct: 80 RQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVED 139
Query: 422 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYL 601
+ F D W+++E GL +++GVSNF+ K+LQ +L A+++PV +QVE +
Sbjct: 140 LLPF---DVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAW 196
Query: 602 NQKRLKQFCEDRDI 643
QK+L++FC++ I
Sbjct: 197 QQKKLREFCKENGI 210
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 161 bits (391), Expect = 1e-38
Identities = 86/202 (42%), Positives = 126/202 (62%), Gaps = 2/202 (0%)
Frame = +2
Query: 44 VTTLSNGAKIPVIGIGTW-KSKPGEVT-QAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
V L G IP++G+GT+ K E T AV AI IGYRH D A +YG+E+ +G A+
Sbjct: 5 VARLRCGETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQ 64
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
I G V+R+DLF+TSKLW++ H + AL +L+ + +DYLD YL+HWP K +
Sbjct: 65 AISYGTVQRDDLFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLKPGVS 122
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
P + + + D+ +TW+ +E + GL RS+GVSNF+SK++ +LD ASV P N
Sbjct: 123 E-PIPKEDEFE-KDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVN 180
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVE HP Q++L++ CE+ +I
Sbjct: 181 QVEMHPLWRQRKLRKVCEENNI 202
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 161 bits (391), Expect = 1e-38
Identities = 89/214 (41%), Positives = 131/214 (61%), Gaps = 11/214 (5%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
S + +L+ GA+IP IG+GTW+SK + +AV A+ GYRHID A +Y NE +VG+AIK
Sbjct: 8 STKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK 67
Query: 215 TKIQEGVVKREDLFITSKLWNT-FHRPDLVRGALEVSLRNLNIDYLDLYLIHWP----QA 379
+ V RE++F+T+KLW T H P++ AL+ SL+ L +DY+DLYL+HWP A
Sbjct: 68 ----DSGVPREEIFVTTKLWCTQHHEPEV---ALDQSLKRLGLDYVDLYLMHWPARLDPA 120
Query: 380 Y--KEDDAIFPTDADGK--IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 547
Y ED PT DG + ++ +++ TW+ ++ L G +++GVSNF+ L+ +L
Sbjct: 121 YIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLL 180
Query: 548 DNASVK--PVTNQVECHPYLNQKRLKQFCEDRDI 643
+ K P NQVE HP L Q L FC+ + I
Sbjct: 181 ASQGNKLTPAANQVEIHPLLPQDELINFCKSKGI 214
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 161 bits (390), Expect = 2e-38
Identities = 82/197 (41%), Positives = 119/197 (60%), Gaps = 4/197 (2%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TLS+G ++PVIG+G W+ + E+ + + +AI IGYRH DCA Y +E +VGEA+ +
Sbjct: 5 TLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFKT 64
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G+VKRE+LFIT+K+WN+ H V A + SL L IDYLDLYL+H+P K +
Sbjct: 65 GLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTA 122
Query: 410 DADGKIQFSDVDYV----DTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
G+ + D+D TW+ +E V GLVRS+G+SN+ + L + +KP +
Sbjct: 123 SLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVS 182
Query: 578 QVECHPYLNQKRLKQFC 628
Q E HPY + L +FC
Sbjct: 183 QFETHPYFQRDSLVKFC 199
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 161 bits (390), Expect = 2e-38
Identities = 88/201 (43%), Positives = 120/201 (59%), Gaps = 1/201 (0%)
Frame = +2
Query: 44 VTTLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
+ TLSNG K+P G+G W+S GEVT+ AV A+ GYRHID A +Y NE+ VG ++
Sbjct: 8 MVTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGLRAS 67
Query: 221 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 400
V RED+FIT+KLWNT + A E S + L +DY+DLYLIHWP+ D +
Sbjct: 68 ----GVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG---KDIL 120
Query: 401 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQ 580
+GK Y+D+W+A E L VR++GVSNF+ L+ +L +V P+ NQ
Sbjct: 121 ---SKEGK------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQ 171
Query: 581 VECHPYLNQKRLKQFCEDRDI 643
VE HP NQ L+ FC+ + I
Sbjct: 172 VELHPLNNQADLRAFCDAKQI 192
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 160 bits (389), Expect = 2e-38
Identities = 83/199 (41%), Positives = 125/199 (62%), Gaps = 1/199 (0%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+ GAKIP +G+GT++ P + V + G R ID A VYG E++VG IK +
Sbjct: 39 TLNTGAKIPALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGIK----K 93
Query: 230 GVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
V RE++F+ +KLW N FH PD V A++ SLR+L Y+DL L+H+P +K + FP
Sbjct: 94 SGVPREEIFLGTKLWCNDFH-PDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDRFP 152
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
DA+G++ + +VDTW+ALE +V G VR++GVSNF+ +++ +L S P +Q+E
Sbjct: 153 RDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQME 212
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HPYL QK ++ ++ I
Sbjct: 213 VHPYLQQKGFNEWLREKGI 231
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 160 bits (388), Expect = 3e-38
Identities = 83/204 (40%), Positives = 123/204 (60%)
Frame = +2
Query: 32 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAI 211
+ VP+ TLSNG +P IG+GTW+ E +++A+ GYRHID A +Y NE ++G+A+
Sbjct: 3 SKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDAL 62
Query: 212 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
EG++KRED+FIT+K + PD+V AL SL+ L +DY+DLYL H P + K+
Sbjct: 63 AELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKD- 121
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
DG + SDV D W+ E + GL +++GVSNFN Q+ RI++ V
Sbjct: 122 --------DGSFR-SDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIH 172
Query: 572 TNQVECHPYLNQKRLKQFCEDRDI 643
+Q+E H YL QK ++ C+ +I
Sbjct: 173 ASQLELHLYLPQKAHRELCKKHNI 196
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 159 bits (387), Expect = 4e-38
Identities = 85/203 (41%), Positives = 119/203 (58%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
+VP L++G +IP +G G ++ +PG+ QAVK A+D+GYRHID A +YGNE EV +
Sbjct: 11 TVPTILLNDGREIPQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEVAQG-- 68
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
I + V R+++++TSKL N FH PD R A++ S+ L +DLYLIHWP
Sbjct: 69 --IADSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHWP------- 118
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
PT G D+V TWK LE G +RS+GVSNF LQR+ A+V P
Sbjct: 119 --LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAV 169
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HPY + +++ C + I
Sbjct: 170 NQIEVHPYFGNEEVRRHCGEHQI 192
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 159 bits (385), Expect = 7e-38
Identities = 79/199 (39%), Positives = 121/199 (60%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L NG +P+IG GTW+++ E+ A+ A++ GYRHID A Y NEK +G+ +K
Sbjct: 8 LPNGELMPIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSK 67
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDDAIFPT 409
+KR D+FI +KL +R + V ++ SL+NL ++YLDLYLIH P + K D + P
Sbjct: 68 KLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPF 127
Query: 410 DADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
D +G I+ + ++V+ W +E V G +++G+SNFN Q++RIL N +K Q+E
Sbjct: 128 DENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKISMLQIE 187
Query: 587 CHPYLNQKRLKQFCEDRDI 643
H Y QK L +FC+ +I
Sbjct: 188 LHVYFQQKELVKFCKQENI 206
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 158 bits (384), Expect = 9e-38
Identities = 86/192 (44%), Positives = 118/192 (61%), Gaps = 1/192 (0%)
Frame = +2
Query: 23 LIMTSVPVT-TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEV 199
L +T++ T L+NG KIP +G GT+++ QAVK+AI+ GYRHID A VYGNE+ V
Sbjct: 2 LELTNINSTFNLNNGVKIPCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAV 61
Query: 200 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 379
G+ IK + +KREDLF+TSKLWNT + + A + +L L +DYLDLYLIHWP
Sbjct: 62 GKGIK----DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPAN 117
Query: 380 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 559
K+ F DA KI +TW+A+E L G +R++GVSNF + ++ A
Sbjct: 118 EKQ----FGDDA-AKIN------AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAK 166
Query: 560 VKPVTNQVECHP 595
V P +Q+E HP
Sbjct: 167 VAPAVDQIEVHP 178
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 158 bits (384), Expect = 9e-38
Identities = 85/213 (39%), Positives = 126/213 (59%), Gaps = 4/213 (1%)
Frame = +2
Query: 17 SNLIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIDCAFVYGNEK 193
S+ + + TL+NG KIP IG+GTW + + +A A+ GY+HID A YGNE
Sbjct: 2 SSQLSINTKTYTLNNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNED 61
Query: 194 EVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 373
+VG AI + V R+++F+T+KLWN H+ GAL+ SL+ L ++Y+DLYLIHWP
Sbjct: 62 QVGRAIA----DSGVSRDEIFVTTKLWNDQHKDP--EGALDESLKKLGLEYVDLYLIHWP 115
Query: 374 QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHG-LVRSLGVSNFNSKQLQRIL- 547
D + + D D+VDTW+ L+ + G V+++GVSNFN K+L ++L
Sbjct: 116 ---------LSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLN 166
Query: 548 -DNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
+ +V PV NQ+E HP L Q L + + +DI
Sbjct: 167 SEGVNVVPVINQIEAHPLLTQPDLFDYLKSKDI 199
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 158 bits (384), Expect = 9e-38
Identities = 85/208 (40%), Positives = 130/208 (62%), Gaps = 11/208 (5%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSK-PGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
LSNG IP +G+GT + P E+ + V A+ GYRHID A+ YG E+ +G+A+K +E
Sbjct: 12 LSNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLFEE 71
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF-- 403
G+VKREDLFIT+K+W +F R +L+ SL +L +DY+DL+L HWP D+
Sbjct: 72 GIVKREDLFITTKVWPSFWRNP--EKSLDKSLADLGLDYVDLFLQHWPVVLHGDENGLPP 129
Query: 404 -PTDADGKIQFSD-----VDYVDTWKALEPLVCH-GLVRSLGVSNFNSKQLQRILDNA-S 559
P D DGK+ + D + Y+D + +LE ++ + V+S+GVSN++ +L+++L
Sbjct: 130 QPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRKLLAAVRK 189
Query: 560 VKPVTNQVECHPYLNQKRLKQFCEDRDI 643
KPV NQ+E HP L Q+ L ++C D +
Sbjct: 190 HKPVVNQIEYHPLLPQQDLVKYCYDNGV 217
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 156 bits (379), Expect = 4e-37
Identities = 82/213 (38%), Positives = 126/213 (59%), Gaps = 8/213 (3%)
Frame = +2
Query: 29 MTSVPVTTLSNGA--KIPVIGIGTWKS---KPGEVTQAVKDAIDIGYRHIDCAFVYGNEK 193
M +VP L +GA +P +G+GT S P A A+++G+RH D A +YG E
Sbjct: 1 MAAVPEVALRHGAGRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEA 60
Query: 194 EVGEAIKTKIQEGVV-KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 370
+GEAI + G+V RE++F+T+KLW T P LV +L SLRNL ++Y+DLYL+HW
Sbjct: 61 PLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHW 120
Query: 371 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRI 544
P + K + P + + F D+ W+A+E CH GL +++GVSNF +K L ++
Sbjct: 121 PISVKPGPPMLPVKREDAVPF---DFEGVWRAMEE--CHRLGLAKAIGVSNFTTKHLDKL 175
Query: 545 LDNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
L A++ P NQVE +P Q+ ++++C + I
Sbjct: 176 LAVATIPPAVNQVEMNPVWQQRTVREYCAAKGI 208
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 156 bits (378), Expect = 5e-37
Identities = 81/198 (40%), Positives = 114/198 (57%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TLSNG ++P +GIGTW++K G +K A++ GYRH+D A Y NEK VG+ I E
Sbjct: 9 TLSNGVQVPQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQG----ISE 64
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V R D+F+T+KLWN H + A E S + L ++Y+DLYLIHWP +
Sbjct: 65 CGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWPGPNR-------- 116
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
Y++TW+A E L VR++GVSNF L +L N +V P+ NQVE
Sbjct: 117 -----------SYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEM 165
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP+ QK L+ +C +++I
Sbjct: 166 HPHFQQKALRAYCAEKNI 183
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 155 bits (377), Expect = 7e-37
Identities = 80/198 (40%), Positives = 121/198 (61%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L +G +P +G+GTW++ + +V+ AI + GYRH+D A YG EKEVG+ +K ++
Sbjct: 18 LKSGHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEA 76
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G+ R+DLF+TSK+W T P+ VR ALE +L++L +DY+DLY IHWP K D A P
Sbjct: 77 GI-DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK-DGAHMPP 134
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+A ++F D WK +E LV GLV+ +GV N+ +L R+L +A + P Q+E
Sbjct: 135 EAGEVLEF---DMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEM 191
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP ++ + C+ I
Sbjct: 192 HPGWKNDKIFEACKKHGI 209
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 155 bits (376), Expect = 9e-37
Identities = 79/198 (39%), Positives = 118/198 (59%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+NG +P +G G +K EV +AV++A+ +GYR ID A +Y NE VG A+K +
Sbjct: 5 TLNNGLVMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRALK----D 60
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+ RED+F+T+K+WN + A E SL+ L +DY+DLYLIHWP ++D
Sbjct: 61 SGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM--PDEDL---- 114
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
Y+DTW+ALE L G +++GVSNF+ L R+L+ +V P NQ+E
Sbjct: 115 ------------YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIEL 162
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP+L+Q+ ++ FC+ I
Sbjct: 163 HPFLSQEAIRAFCQKNGI 180
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 154 bits (374), Expect = 2e-36
Identities = 76/192 (39%), Positives = 112/192 (58%), Gaps = 1/192 (0%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE-GVVKRE 247
+P IG+GT+ + +A++ AID+GYR D A YGNE VGEAI+ KI+E + R+
Sbjct: 17 LPTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRD 76
Query: 248 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 427
D FI SKL ++HR DLV ++L L +DY+DLYL+H P A + +
Sbjct: 77 DFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNA 136
Query: 428 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQ 607
+ + W LE GL RS+GVSNFN Q+ +L +AS+ P NQ+EC NQ
Sbjct: 137 IDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQ 196
Query: 608 KRLKQFCEDRDI 643
+ +++FC+ ++I
Sbjct: 197 RPMRKFCQQQNI 208
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 154 bits (373), Expect = 2e-36
Identities = 82/196 (41%), Positives = 114/196 (58%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M + P+ L++G +P +G+G+W S ++ + + A+DIGYR ID A +Y NEK VG A
Sbjct: 1 MDNQPIIRLADGNHMPQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA 60
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
+QE + RED+F+T+KLWN H R AL SL L +DY+DLYLIHWP
Sbjct: 61 ----LQETDIPREDIFVTTKLWNDRHLD--ARAALTESLEKLQLDYVDLYLIHWPAP--- 111
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
P D YV W+ L L GL+RS+GVSNF + +QR+++ V P
Sbjct: 112 -----PQD----------QYVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHP 156
Query: 569 VTNQVECHPYLNQKRL 616
V NQ+E HP L Q++L
Sbjct: 157 VINQIELHPLLQQRQL 172
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 154 bits (373), Expect = 2e-36
Identities = 83/198 (41%), Positives = 115/198 (58%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+N IP IG GTW++ G+ A+K AID GY+HID A +Y NEK VG IK E
Sbjct: 7 LNNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGIK----E 62
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+ R+DLF+TSK+WN + A + ++ +L +DYLDLYLIHWP A +
Sbjct: 63 ANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQ------- 115
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+ Q ++ DTW A+E L G +++LGVSNF L +L +A++KP NQ+E
Sbjct: 116 -FENWKQLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEY 170
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP Q+ QFC D +I
Sbjct: 171 HPGYMQQDCVQFCNDNNI 188
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 154 bits (373), Expect = 2e-36
Identities = 83/211 (39%), Positives = 119/211 (56%), Gaps = 6/211 (2%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIDCAFVYGNE 190
MT +P L++G+ IPV+G+GT K VT ++ A++ GYRH D A YGNE
Sbjct: 8 MTKIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNE 67
Query: 191 KEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 370
+G+ ++ I EG VKRE+LFIT+KL +R V L+ SL NL + Y+DLYL+H+
Sbjct: 68 AIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHY 127
Query: 371 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 550
P + D AD D W+A+E + G +++G+SNFN+ Q+QRI+
Sbjct: 128 PCGILDTDR-ERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIK 186
Query: 551 NASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
V+P QVE H Y+ Q L+ FC DI
Sbjct: 187 GCQVRPAVLQVEVHVYMQQGALRAFCAQHDI 217
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 154 bits (373), Expect = 2e-36
Identities = 89/202 (44%), Positives = 123/202 (60%), Gaps = 5/202 (2%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
L++G +PV+G GT+ + + +A K AID+G+RHID A++Y NE+EVG+AI KI
Sbjct: 13 LNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKI 72
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDAI 400
+G VKRE++F T KLW TF R +LV ALE SL+ L DY+DL++IH P A K+ +
Sbjct: 73 ADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGKEL 132
Query: 401 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQ 580
P DA G+I V+ DTW+ LE ++ N L+ KP NQ
Sbjct: 133 LPKDASGEIILETVELCDTWE-LELIL-------------NKPGLR-------YKPTCNQ 171
Query: 581 -VECHPYLNQKRLKQFCEDRDI 643
VECHPYLNQ +L +FC+ +DI
Sbjct: 172 VVECHPYLNQSKLLEFCKSKDI 193
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 153 bits (371), Expect = 3e-36
Identities = 87/209 (41%), Positives = 114/209 (54%), Gaps = 2/209 (0%)
Frame = +2
Query: 23 LIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVG 202
+I + TL+NG KIP +G+G ++ E + V++ I GYR ID A +YGNE G
Sbjct: 1 MITSLADTVTLNNGTKIPGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTG 60
Query: 203 EAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP--Q 376
IK + + REDLF+TSK+WN D A SL L +DYLDLYLIHWP
Sbjct: 61 AGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWPGNN 120
Query: 377 AYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 556
+YKE +W+ALE L G V+++GVSNF L+ +L A
Sbjct: 121 SYKE----------------------SWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYA 158
Query: 557 SVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
V PV NQVE HP L+QK ++ FCE DI
Sbjct: 159 KVVPVINQVELHPKLDQKEVRDFCEKHDI 187
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 153 bits (371), Expect = 3e-36
Identities = 77/183 (42%), Positives = 115/183 (62%), Gaps = 1/183 (0%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQ 226
TL+NG KIP+IG GTW++ GEV + +V A++ GYRHID A YGNE VG AI Q
Sbjct: 11 TLNNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAI----Q 66
Query: 227 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
+ + R +LFIT+KLWN+ H + + A++ SL +L +DYLD+YLIHWP D
Sbjct: 67 KSGINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSMRD---- 122
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
+++++ ++W+A+E V G +R++GVSNF L +++ A +KPV NQ+
Sbjct: 123 -------HWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIF 174
Query: 587 CHP 595
+P
Sbjct: 175 LNP 177
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 153 bits (371), Expect = 3e-36
Identities = 89/198 (44%), Positives = 116/198 (58%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L NG ++P G+G +K + G E T++VK AI GYR ID A +Y NE+ VG IK E
Sbjct: 11 LHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIK----E 66
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V RE+LFITSK+WN + A E SL L +DYLDLYLIHWP
Sbjct: 67 SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP------------ 114
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
GK + Y DTW+ALE L G +R++GVSNF L+ +L +A +KP+ NQVE
Sbjct: 115 ---GKDK-----YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEF 166
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP L QK L+ +C+ + I
Sbjct: 167 HPRLTQKELRDYCKAQGI 184
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 153 bits (371), Expect = 3e-36
Identities = 85/203 (41%), Positives = 121/203 (59%), Gaps = 2/203 (0%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
P+ L++G IP + +GT+ +V QAV AI GYRHID A +YGNE+EVG+ I
Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIAD 84
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED-D 394
IQ+G+VKRE+LF+T+KLWN H V AL SL L + Y+DLYLIH P+A E+ D
Sbjct: 85 AIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSPEATNENGD 144
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
+ D+D ++TW +E GL +S+GVSNF++ L R++ ++ P
Sbjct: 145 PV------------DIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAV 192
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HP Q++L +R I
Sbjct: 193 NQIEVHPSKTQEKLVADSHERGI 215
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 152 bits (369), Expect = 6e-36
Identities = 81/199 (40%), Positives = 116/199 (58%), Gaps = 7/199 (3%)
Frame = +2
Query: 68 KIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRE 247
K+P+ G G WK + + + AI IGYR D A YGNE EVG I I+EG+VKRE
Sbjct: 14 KMPLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKRE 73
Query: 248 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW--PQAYKEDDAIFPTD--- 412
+LFI +KLWNTFH VR A + L++ ++Y DLYLIH+ P Y + +P +
Sbjct: 74 ELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYV 133
Query: 413 --ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
AD K+ F + W +E LV L R++GV+NFN + + +L A +KP Q+E
Sbjct: 134 PHAD-KLNFERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIE 192
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HP L Q+RL ++ +++ I
Sbjct: 193 IHPLLPQERLVKWVQEQGI 211
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 152 bits (368), Expect = 8e-36
Identities = 82/198 (41%), Positives = 117/198 (59%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG +P++G+G WK+K G E +AV +A++ GYRHID A +Y NE +VG+AI+ E
Sbjct: 14 LNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQAIR----E 69
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+ R+++FIT+KLWN D R ALE SL L ID++DLYLIH+P K
Sbjct: 70 SGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSKR------- 122
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+D+WK LE L L +++GVSN+ L +L N+ + P NQVE
Sbjct: 123 -------------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEF 169
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP+LNQ L ++C+ I
Sbjct: 170 HPFLNQIHLLEYCKKHKI 187
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 151 bits (367), Expect = 1e-35
Identities = 77/200 (38%), Positives = 117/200 (58%)
Frame = +2
Query: 44 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
V L+NG +P +G+G +K ++ + V+ A+D GYR D A+ YGNEK +G A+K
Sbjct: 5 VQILNNGYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSALK--- 61
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 403
V+R++LFITSKLWN + D SL NL +DYLDL+LIHWP E+D +
Sbjct: 62 -HSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP---CENDQL- 116
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 583
Y++++KALE L G ++++GV NF L++++ + P NQ+
Sbjct: 117 --------------YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQI 162
Query: 584 ECHPYLNQKRLKQFCEDRDI 643
E HPY NQ+ ++ FC++ DI
Sbjct: 163 ELHPYFNQQDVQDFCDEHDI 182
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 151 bits (365), Expect = 2e-35
Identities = 83/215 (38%), Positives = 124/215 (57%), Gaps = 9/215 (4%)
Frame = +2
Query: 26 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE 205
+ S L+ G IP +G+GTW+SK E +AV +A+ GYRHID A VYGNE EVG+
Sbjct: 4 LQNSTSTLKLNTGQTIPQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGK 63
Query: 206 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
A IQ+ V R ++F+T+KLW T R + AL+ SL+ L +DY+ LYL+HWP +
Sbjct: 64 A----IQDSGVPRNEIFLTTKLWCTHQRNP--QEALDQSLQRLGLDYVGLYLVHWPVPLR 117
Query: 386 EDDA------IFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 544
++ F DG + +++ TW+ ++ L+ G +++GVSNF+ L+ +
Sbjct: 118 TENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDL 177
Query: 545 L--DNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
L V P NQVE HP L Q+ L Q+C ++ I
Sbjct: 178 LAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGI 212
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 150 bits (364), Expect = 2e-35
Identities = 83/208 (39%), Positives = 122/208 (58%), Gaps = 1/208 (0%)
Frame = +2
Query: 23 LIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAFVYGNEKEV 199
++ +P ++NG +IP +G+G ++ E T+ A+K A+ GYRHID A YGNE+ V
Sbjct: 6 ILHNDIPDLPMNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWV 65
Query: 200 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 379
GEAI+ E V R+ +F+TSKLWN+ D + A + +L L +DYLDLYLIHWP
Sbjct: 66 GEAIR----ESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP-- 119
Query: 380 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 559
A G Y+D+W+A+E L G ++++GVSNFN Q+ IL + +
Sbjct: 120 -----------APG--------YLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGT 160
Query: 560 VKPVTNQVECHPYLNQKRLKQFCEDRDI 643
VKPV +Q+E HPY Q + + E + I
Sbjct: 161 VKPVVDQIETHPYFQQNDMHAYLESQGI 188
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 150 bits (363), Expect = 3e-35
Identities = 83/215 (38%), Positives = 129/215 (60%), Gaps = 12/215 (5%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPG-----EVTQAVKDAIDIGYRHIDCAFVYGNEKEV 199
++P TL+ GAK+P +G+G W+ +PG E+ A+ AI +GYRH+D A Y NE EV
Sbjct: 4 NIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAEV 63
Query: 200 GEAIKTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQ 376
G+A++ Q GV R ++F+T+KL H D+V+ LE SL L IDY+DL+L+HWPQ
Sbjct: 64 GQAVR---QSGVA-RSEIFVTTKLRPGGVH--DVVQ-ELENSLNELGIDYIDLWLLHWPQ 116
Query: 377 AYKEDDAIFPTDADGKIQFSD---VDYVDTWKALEPLVCH---GLVRSLGVSNFNSKQLQ 538
+ +DD F T ++ + +TW +E + + G V+++GVSNF+ K L+
Sbjct: 117 GFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKNLE 176
Query: 539 RILDNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
+ + V P NQ+E HPYL + L ++C+ + I
Sbjct: 177 ILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSI 211
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 149 bits (361), Expect = 6e-35
Identities = 86/202 (42%), Positives = 113/202 (55%), Gaps = 5/202 (2%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKS---KPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
VP L GA +P IGIGT+ S P EV AV A+ GYR +DCA VYGNE +VGEA
Sbjct: 13 VPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEA 72
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
+ + G V R++LF+ SK+WN H P ++ SLR+L +D+LD +HWP
Sbjct: 73 LAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFP-NH 130
Query: 389 DDAIFPTDA-DGKIQFSDVD-YVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 562
+ TDA D + + D D Y+ W ALE LV GLVR LG SN +L +L +A +
Sbjct: 131 HPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDARI 190
Query: 563 KPVTNQVECHPYLNQKRLKQFC 628
P N++E HP Q L C
Sbjct: 191 PPALNEMELHPCFQQPELFAHC 212
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 149 bits (360), Expect = 7e-35
Identities = 87/201 (43%), Positives = 125/201 (62%), Gaps = 4/201 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKD-AIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG +P++GIGT+K + EV + V D + +G+R ID A VY NE+++G A+K + +
Sbjct: 28 LNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIGLALKELLPK 87
Query: 230 GVVKREDLFITSKLWNTFH-RPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
+KRED+FITSKL + + PD +R ++E SL+ L+ YLDLYLIHWP A + I
Sbjct: 88 YNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGASR----ILE 143
Query: 407 TDADG-KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS-VKPVTNQ 580
D K++ V TW L L GL+RS+GVSN+ L+ +L++ S VKP NQ
Sbjct: 144 NSPDNPKLR------VTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGVKPDVNQ 197
Query: 581 VECHPYLNQKRLKQFCEDRDI 643
VECHP+ Q L +FC + I
Sbjct: 198 VECHPHFRQDELIEFCTKQGI 218
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 149 bits (360), Expect = 7e-35
Identities = 82/212 (38%), Positives = 124/212 (58%), Gaps = 7/212 (3%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKD----AIDIGYRHIDCAFVYGNEKE 196
M++ P L+ GA++P + +G W E K+ A+ GYRHID A +Y EK
Sbjct: 1 MSAYPPIVLNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKS 60
Query: 197 VGEAIKTKIQEGVVKREDLFITSKL-WNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 373
VG AI+ E + RE+LFIT+KL WN R V + + SL NL +Y+DLYL+H+P
Sbjct: 61 VGNAIR----ESGIPREELFITTKLPWNHHSR---VAESFQKSLENLGTEYIDLYLVHFP 113
Query: 374 Q-AYKEDDAIFPTDADGKIQFSDVDYV-DTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 547
Q + ++ FP + DG I+ + + D W +E L+ G V+++GVSN++ K L+ +L
Sbjct: 114 QRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELL 173
Query: 548 DNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
A V P NQVE HP+L Q +L +C+++ I
Sbjct: 174 KTAKVVPAVNQVELHPFLAQSKLLAYCKEKGI 205
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 148 bits (359), Expect = 1e-34
Identities = 80/183 (43%), Positives = 105/183 (57%), Gaps = 1/183 (0%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQ 226
TL+NG KIP++G GTW++ G+V +V A+ GYRHID A YGNE+ VG+AI
Sbjct: 12 TLNNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA---- 67
Query: 227 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
+ V REDLF+T+KLWN H D + AL+ SL L +DY+DLYLIHWP D
Sbjct: 68 DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAMRDNWEQ 127
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
+A DTW+A+E R++GVSNF K L +L A V P NQ+
Sbjct: 128 LNA------------DTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQIF 175
Query: 587 CHP 595
+P
Sbjct: 176 LNP 178
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 148 bits (359), Expect = 1e-34
Identities = 79/210 (37%), Positives = 121/210 (57%), Gaps = 8/210 (3%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWK-----SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVG 202
+P LS+G +P +G+GT + P V V AI+ GYRH D A VY E +G
Sbjct: 1 MPEAALSSGKPMPRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60
Query: 203 EAIKTKIQEGVV-KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 379
+A+ ++ G+V R++L+ITSKLW P V +L +LR + ++YLDLYLIH+P +
Sbjct: 61 DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120
Query: 380 YK--EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
+ ED D + +D WK +E GL +++GVSNF+ K+L+ +L
Sbjct: 121 MRLAEDPESMTYSKDDLVM---MDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSF 177
Query: 554 ASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
A++ P NQVE HPY Q +L++FC+++ I
Sbjct: 178 ATISPAANQVEVHPYCRQNKLREFCKEKGI 207
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 148 bits (358), Expect = 1e-34
Identities = 82/197 (41%), Positives = 114/197 (57%), Gaps = 1/197 (0%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
MT P+ L +G +P +G+G W++ E AV A+++GYR ID A +Y NE+ VG+A
Sbjct: 1 MTMQPLIKLYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKA 60
Query: 209 IKTKIQEGVVKREDLFITSKLWN-TFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
+K V R++LFIT+KLWN H P + ALE SL+ L +DY+DLYLIHWP K
Sbjct: 61 LKA----AAVARDELFITTKLWNDDQHNP---QQALETSLQKLQLDYVDLYLIHWPDP-K 112
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
+D YV W+ L L GL+RS+GV NF+ LQR++D +
Sbjct: 113 QD-----------------HYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIA 155
Query: 566 PVTNQVECHPYLNQKRL 616
P NQ+E HP L Q++L
Sbjct: 156 PTVNQIELHPLLQQRQL 172
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 147 bits (357), Expect = 2e-34
Identities = 76/196 (38%), Positives = 119/196 (60%), Gaps = 1/196 (0%)
Frame = +2
Query: 47 TTLSNGAKIPVIGIGTWKS-KPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
T L NG+K+PV G+GT+K E+ ++ A+D+GYRHID A +Y NEK++G+A++
Sbjct: 8 TELCNGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIY 67
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 403
+EG KREDLF+ +KL++ ++ V + SL+NL +Y+DLYL+H+ +
Sbjct: 68 KEGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSP------- 118
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 583
PTD + + + W E LV GL+R++G+SNFN + L + +KPV NQ+
Sbjct: 119 PTD---QFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQI 175
Query: 584 ECHPYLNQKRLKQFCE 631
E + Y Q RL +FC+
Sbjct: 176 EVNVYCQQPRLLEFCK 191
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 147 bits (357), Expect = 2e-34
Identities = 76/194 (39%), Positives = 105/194 (54%), Gaps = 4/194 (2%)
Frame = +2
Query: 74 PVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGV--VKRE 247
P +G GT+ + E A++ A+ +GYRH DCA+ YGNE+ +GE K + VKRE
Sbjct: 6 PCVGFGTYLVEDPE---AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKRE 62
Query: 248 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE--DDAIFPTDADG 421
DL+I SKLW FH P+ V + +LR+L ++YLD++L+HWP A K D +D G
Sbjct: 63 DLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKG 122
Query: 422 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYL 601
TW+A+E V R +GVSN + L +L +KP TNQ E PY
Sbjct: 123 GTLLGTTPIRKTWEAMEACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYF 182
Query: 602 NQKRLKQFCEDRDI 643
RL +FC I
Sbjct: 183 PNDRLIEFCNSNGI 196
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 147 bits (357), Expect = 2e-34
Identities = 80/187 (42%), Positives = 106/187 (56%), Gaps = 12/187 (6%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRED 250
IP +G GT++ E T AV A+ GYRH+DCA YGNE VGEA+ ++ +RED
Sbjct: 30 IPQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRRED 89
Query: 251 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA------YKEDDAIFPTD 412
LF+TSKLW T PD V A +L L +DYLDLYLIHWP + D+ +P
Sbjct: 90 LFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRH 149
Query: 413 ADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN-ASVK----PVT 574
DG + V +DTW A+ LV GLV+S+G++N + + ++ A K PV
Sbjct: 150 RDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLPVL 209
Query: 575 NQVECHP 595
NQVE HP
Sbjct: 210 NQVEHHP 216
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 147 bits (355), Expect = 3e-34
Identities = 79/203 (38%), Positives = 115/203 (56%), Gaps = 3/203 (1%)
Frame = +2
Query: 44 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
V LS+G P++G+GT + + A++ G HID +FVY NE+ +G+ +K
Sbjct: 30 VYRLSSGHNFPIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWF 89
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA--YKEDDA 397
+G KRED+F+TSKL + P+ V +++SL L + YLD+YLIH P A +KED
Sbjct: 90 AKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSY 148
Query: 398 IFPTDADGKIQF-SDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
T+ DG + + D + WK +E V G +S+G+SNFN Q+ IL A +KP
Sbjct: 149 ELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSN 208
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
QVE H Y QK L +FC+ I
Sbjct: 209 LQVEVHAYHQQKPLIEFCQKNGI 231
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 146 bits (354), Expect = 4e-34
Identities = 81/204 (39%), Positives = 113/204 (55%)
Frame = +2
Query: 32 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAI 211
+ VP L+NG ++P +G G W+ + AV A++ GYR ID A +YGNE+ G AI
Sbjct: 3 SKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGRAI 62
Query: 212 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
G+ REDLF+T+KLWN+ D A + S+ L ++YLDLYLIHWP KE
Sbjct: 63 AAS---GLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAKE- 117
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
YVDT+KA E L+ G VR++GVSNF + L+R+ SV P
Sbjct: 118 -----------------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPA 160
Query: 572 TNQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HP+L Q ++ ++ I
Sbjct: 161 VNQIELHPHLQQHAAREVHAEQGI 184
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 144 bits (350), Expect = 1e-33
Identities = 79/205 (38%), Positives = 126/205 (61%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M +P+ L+NG +IPV G+ + EV + V+ + YR +DC+ ++ NEK G A
Sbjct: 5 MRDIPIAKLNNGIEIPVFGLAAPQDF-FEV-ENVQLVVSSNYRLMDCS-IFENEKRFGVA 61
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
++ I+ G ++R+DLF+ SK T + +LV+ AL +L+ L + YLDLYLI P A K
Sbjct: 62 LQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPPACK- 119
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
D + ++TW+A+E L L R++G+SNFNSKQ++RIL+N +++P
Sbjct: 120 ----------------DHNLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRP 163
Query: 569 VTNQVECHPYLNQKRLKQFCEDRDI 643
NQ++CHPYLNQ +L+++C + I
Sbjct: 164 QVNQIQCHPYLNQAKLRKYCSNNGI 188
Score = 139 bits (336), Expect = 6e-32
Identities = 68/150 (45%), Positives = 96/150 (64%), Gaps = 5/150 (3%)
Frame = +2
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFH-RPD---LVRGALEVSLRNLNIDYLDLYLIHWPQ 376
+K +Q G + D+ I S + F+ P+ + SL+NL +DYLD+YL+HWP
Sbjct: 231 LKYNVQLGNIVISDMLIESANFFDFYLAPEDMSYISTFSSESLKNLQLDYLDVYLMHWPH 290
Query: 377 AYKEDDAIFPTDAD-GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
A KE ++ P D G SDVD+VDTWKA+E + L +S+G+SNFNS Q+ R+L +
Sbjct: 291 ALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDLTKSIGISNFNSNQIDRLLKS 350
Query: 554 ASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
A + PV NQ+ECHPYLNQ +L++FC DR I
Sbjct: 351 AKIAPVINQIECHPYLNQSKLRKFCSDRGI 380
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 144 bits (348), Expect = 2e-33
Identities = 81/199 (40%), Positives = 108/199 (54%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M +P LS+G IP +G+G W+ ++ A + GYR ID A +YGNE+ VG A
Sbjct: 56 MRMIPTLPLSDGTSIPQLGLGVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRA 115
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
I+ + R++L+IT+K+WN+ D A+ SL L ++Y+DLYLIHWP
Sbjct: 116 IRA----SGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPVP--- 168
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
KI YVDTWKAL + GL RS+GVSNF LQR+ D + P
Sbjct: 169 -----------KID----RYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVP 213
Query: 569 VTNQVECHPYLNQKRLKQF 625
V NQVE HP L Q L+ F
Sbjct: 214 VVNQVELHPRLQQHELRAF 232
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 144 bits (348), Expect = 2e-33
Identities = 86/226 (38%), Positives = 122/226 (53%), Gaps = 29/226 (12%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-----------------IGYRHI------ 163
L+ GA+IPVIG+GTW+S PGEV +AV+ AI +GY +
Sbjct: 16 LNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALHPLYIP 75
Query: 164 ----DCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRN 331
D A++YGNE EVG+ IK V R +LF+T+K+W T+HR L+ SL+
Sbjct: 76 FLAKDAAWIYGNENEVGQGIKAS----GVPRSELFVTTKIWCTYHRQP--EACLDESLQR 129
Query: 332 LNIDYLDLYLIHWP-QAYKEDDAIFPTDADGKIQFS-DVDYVDTWKALEPLVCHGLVRSL 505
L +DY+DL L+HWP K D P + DG D TW+ +E L G +++
Sbjct: 130 LGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAI 189
Query: 506 GVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
GVSN++ L ++L A + P NQVE HP+L Q L ++C D+ I
Sbjct: 190 GVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGI 235
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 143 bits (346), Expect = 4e-33
Identities = 82/204 (40%), Positives = 118/204 (57%), Gaps = 5/204 (2%)
Frame = +2
Query: 32 TSVPVTTLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
T+VP TL++G +PV+G GT S P ++ + A+ +GYRH+D A VYG E VG A
Sbjct: 18 TAVPCVTLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGAA 77
Query: 209 IKTKIQEGVV-KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY- 382
+ ++ G V R +LF+T+KL P V AL SL L +DY+DL+LIHWP A
Sbjct: 78 VAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAIG 137
Query: 383 KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRILDNA 556
K+D A T D D W+ +E CH GL RS+GVSNF++ ++ R+L A
Sbjct: 138 KKDAAGELTWDDLSRGLVPFDMEGVWRGMEE--CHRLGLARSIGVSNFSAAKMSRLLALA 195
Query: 557 SVKPVTNQVECHPYLNQKRLKQFC 628
+V P NQVE + Q+++++ C
Sbjct: 196 AVPPAVNQVEMNVGWRQEKVREVC 219
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 142 bits (344), Expect = 7e-33
Identities = 81/206 (39%), Positives = 118/206 (57%)
Frame = +2
Query: 26 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE 205
++T VP L +G IP G+GT++ P E + V+ AI++GYRHID A +Y NE+EVG
Sbjct: 5 VLTYVPSVLLGDGVSIPQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGR 64
Query: 206 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
AI + +KRE+ F+T+KLWN+ +P R A E SL L++DY+DLYLIHWP
Sbjct: 65 AIAS----SGIKREEFFVTTKLWNS-DQPK-PREAFERSLDLLSLDYVDLYLIHWPCP-- 116
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
P++ Y++ W+ L L G +S+GVSNF S+ + +I +
Sbjct: 117 ------PSEL----------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPL 160
Query: 566 PVTNQVECHPYLNQKRLKQFCEDRDI 643
P NQ+E HP+L Q+ L C + I
Sbjct: 161 PSVNQIELHPWLQQRELVLSCRNDGI 186
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 142 bits (343), Expect = 9e-33
Identities = 76/198 (38%), Positives = 111/198 (56%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKS-KPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG +IP + +G +K+ G A K A D GYRHID A Y NE+ VG A+ +E
Sbjct: 21 LNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWTKE 80
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V R ++FITSKLW+ H D A+E SL+ LN+DY+D+YL+H P + +
Sbjct: 81 NNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSPGTMGAEKRL--- 135
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+ WKALE V G ++++GVSNF+ ++L +L N +KP NQ+E
Sbjct: 136 --------------EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKPAVNQIES 181
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP+ + L++ C R I
Sbjct: 182 HPFFAHEELREACISRGI 199
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 141 bits (342), Expect = 1e-32
Identities = 77/202 (38%), Positives = 117/202 (57%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
VP TL+NG ++P++G G ++ P + + V +AI +GYR ID A Y NE+ VG AIK
Sbjct: 3 VPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKR 62
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
I EG+V+RE+LF+T+KLW + + + A E SL+ L ++Y+DLYLIH P
Sbjct: 63 AIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP-------- 114
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
F DV WKA+E + GLVR++GVSNF +L ++ + + P N
Sbjct: 115 -----------FGDVHC--AWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVN 161
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
Q+E HP+ ++ +F + +I
Sbjct: 162 QIEIHPFYQRQEEIEFMRNYNI 183
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 141 bits (342), Expect = 1e-32
Identities = 81/197 (41%), Positives = 112/197 (56%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
LSNG IP +G GT+K+ G+ + + +AI GYRH D A YG E +G+A+ E
Sbjct: 10 LSNGLSIPAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ES 64
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
+ RED F+TSKLW T D A + +L L DYLDLYLIHWP+ E +
Sbjct: 65 DIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDLELE------ 118
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
++ +D +TW+ALE L GLVR++GVSNF L+ IL +A+V P+ +Q+E H
Sbjct: 119 -----DWAKLDR-ETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFH 172
Query: 593 PYLNQKRLKQFCEDRDI 643
P Q FC++ I
Sbjct: 173 PGYTQDEAVAFCQNHSI 189
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 140 bits (339), Expect = 3e-32
Identities = 73/190 (38%), Positives = 111/190 (58%), Gaps = 1/190 (0%)
Frame = +2
Query: 59 NGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGV 235
NG KIP +G G +K GE + AV +AI IGYRH D A +YGNEK++G AI ++
Sbjct: 12 NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAI----EKSQ 67
Query: 236 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 415
+ RE+ FITSK+WNT H + + A E + + LN++YLD+YLIH+ +Y
Sbjct: 68 IPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------- 116
Query: 416 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHP 595
Y++TW A+E L G ++ +GV+NF + L+ ++ ++ + P+ NQ+E HP
Sbjct: 117 ----------YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITPMINQIETHP 166
Query: 596 YLNQKRLKQF 625
Q L Q+
Sbjct: 167 EFPQNELHQY 176
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 140 bits (338), Expect = 3e-32
Identities = 78/198 (39%), Positives = 114/198 (57%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+NG KIP +G+GTW+ V AV++A +GYRHID A YGNE+ VGEA++ +
Sbjct: 16 TLNNGNKIPKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVR----K 71
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+KRE+LFITSK+ + +++ SL+ + +D++DL LIH PQ P
Sbjct: 72 SKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQ---------PW 122
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
++ K + + V+ + ALE G VRS+GVSNF K L+ IL N KP NQ+ C
Sbjct: 123 NSFRKGDYFK-ENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILC 181
Query: 590 HPYLNQKRLKQFCEDRDI 643
H L +C+ ++I
Sbjct: 182 HIGNTPFTLLDYCKKQNI 199
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 140 bits (338), Expect = 3e-32
Identities = 75/202 (37%), Positives = 117/202 (57%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
+P TL++G ++P IG GT+K + + +AV+ AI++GYRHID A +Y NE+EVG A+
Sbjct: 11 IPTITLNDGTEMPAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVAD 70
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
I G V R++LFIT+K+WN H L + + + SL L +DY+D ++HWP K
Sbjct: 71 AITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWPWPQK---- 126
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
G YV+++ AL + G ++S+ V+NF + L+ I+ + PV N
Sbjct: 127 -------GL-------YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLN 172
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVE HP +Q +Q DR++
Sbjct: 173 QVELHPGFSQ--AEQRAVDREL 192
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 140 bits (338), Expect = 3e-32
Identities = 76/181 (41%), Positives = 110/181 (60%), Gaps = 3/181 (1%)
Frame = +2
Query: 74 PVIGIGTWKSK--PGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRE 247
P+IG GTW K P T+AV AI+IGYR IDCA VYGNE VG I+ ++ +KRE
Sbjct: 40 PLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKRE 99
Query: 248 DLFITSKLWNTFHRP-DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 424
D+++TSKLWN H + V L +L++L ++YLDLYLIHWP + + A
Sbjct: 100 DIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA--------- 150
Query: 425 IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLN 604
++D+V T+K++ L V ++GVSNF+ QL+ ++ ++ P +Q+E HPYL
Sbjct: 151 ---KNLDHVQTYKSMISLP-KSRVLNIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQ 205
Query: 605 Q 607
Q
Sbjct: 206 Q 206
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 140 bits (338), Expect = 3e-32
Identities = 80/203 (39%), Positives = 112/203 (55%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
+VP L++G IP +G G +K P + +AV++A+++GYRHID A +YGNE+ VG AI
Sbjct: 2 TVPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIA 61
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
G+ R+DLFIT+KLWN H D A+ SL L +D +DLYL+HWP
Sbjct: 62 A---SGIA-RDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPT------ 111
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
P AD +YV W+ + L GL RS+GVSN L+RI+ V P
Sbjct: 112 ---PA-AD--------NYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAV 159
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HP Q+ + + D+
Sbjct: 160 NQIELHPAYQQREITDWAAAHDV 182
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 139 bits (337), Expect = 5e-32
Identities = 79/198 (39%), Positives = 119/198 (60%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAV-KDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L++G +IP++G GT+K+ E +++ K A+ +GYR ID +Y NE+ VG+AIK +
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR--- 61
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
GV+ RE++F+T+KLW R AL+ SLR L+++Y+DLYLIHWP +AI
Sbjct: 62 GVL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPA-----NAINYK 115
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
D DTW+A+E L G ++SLGVSNF + L+ + A V P NQ+E
Sbjct: 116 DWQKT-------NADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEF 168
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP Q ++ +FC++ I
Sbjct: 169 HPGYWQPQVTEFCKNHGI 186
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 139 bits (336), Expect = 6e-32
Identities = 80/200 (40%), Positives = 111/200 (55%)
Frame = +2
Query: 44 VTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI 223
V + +G +P IG+G W++ P E + VK+A+ +GYR +D A +Y NE+ VG+
Sbjct: 13 VISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVGK------ 66
Query: 224 QEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 403
G+ ++F+T+KLWN D A E S R L LDLYLIHWP
Sbjct: 67 --GLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP-------- 116
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQV 583
A G+ YV+TWKAL L G V+S+GVSNF S+ L+RI+D V PV NQ+
Sbjct: 117 ---AQGQ-------YVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQI 166
Query: 584 ECHPYLNQKRLKQFCEDRDI 643
E HP Q+ L++F E +I
Sbjct: 167 ELHPDFQQRALREFHEKHNI 186
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 139 bits (336), Expect = 6e-32
Identities = 76/189 (40%), Positives = 113/189 (59%), Gaps = 1/189 (0%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQ 226
TL++G ++P++G G ++ + G QAV DAI GYR ID A YGNE+EVGEAI I
Sbjct: 5 TLASGIEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAIN 64
Query: 227 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
+G+VKRE+LF+TSK+W A++ SL+ LN+DYLDLYLIH P
Sbjct: 65 QGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP----------- 113
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
++DV W+A+E G ++++GVSNF+ QL + + + +KP+ NQ+E
Sbjct: 114 --------YNDV--FGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIE 163
Query: 587 CHPYLNQKR 613
+P+ K+
Sbjct: 164 VNPFQQNKK 172
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 136 bits (330), Expect = 3e-31
Identities = 78/205 (38%), Positives = 109/205 (53%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
MT P L++G +IP +G GTW+ + + QAV AID+GY ID A +YGNEK VG
Sbjct: 1 MTDYPTLNLNDGRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG-- 58
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
+GV + D+F+ +K+WN D A E L L +++D+ LIHWP K+
Sbjct: 59 ------KGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPEKD 112
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
+VDTWKAL L G +S+GVSNF + L+RI+D V P
Sbjct: 113 ------------------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTP 154
Query: 569 VTNQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HP Q+ +++ ED I
Sbjct: 155 ALNQIELHPSFQQRDMRKVHEDLGI 179
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 136 bits (329), Expect = 4e-31
Identities = 81/203 (39%), Positives = 116/203 (57%), Gaps = 13/203 (6%)
Frame = +2
Query: 74 PVIGIGTWKSKPGE--VTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRE 247
P +G+GT++ G V +AV A+ GYRHID A YGNE EVGEAIK E + RE
Sbjct: 47 PAVGLGTFQGDAGNRGVKEAVLQALRCGYRHIDTATAYGNEIEVGEAIK----ESRIPRE 102
Query: 248 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDY-LDLYLIHWPQAYKEDDAIFPTDADGK 424
++ +T+KL T+HR V AL++SL L ++Y L ++L + +Y A P +
Sbjct: 103 EIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHL-YSASSYSVPHAYSPGPDNNT 161
Query: 425 IQFSDV----------DYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
I+ + DY TW A+E LV G ++ +GVSNFN +L+R+L +A + P
Sbjct: 162 IRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIPPAV 221
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HPYL Q L +FC+ I
Sbjct: 222 NQIELHPYLPQVELVRFCKANGI 244
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 136 bits (329), Expect = 4e-31
Identities = 77/208 (37%), Positives = 125/208 (60%), Gaps = 8/208 (3%)
Frame = +2
Query: 29 MTSVPVTTLSNGAK-IPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKE 196
M ++P S + +P +G+GT + + T A+ AI++GYRH D A +Y E
Sbjct: 1 MATIPEVPASELIQTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGC 60
Query: 197 VGEAIKTKIQEGVV-KREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 370
VGEA+ ++ G++ R D+F+TSK+W + H +V A E +LRNL +DY+DL L+HW
Sbjct: 61 VGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHW 119
Query: 371 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRI 544
P + + FP + + D++ V W+ +E CH GL R++GVSNF++K+L+++
Sbjct: 120 PVSLTPGNYDFPFPKEVILPSFDMEGV--WRGMEE--CHRLGLARAIGVSNFSAKKLEQL 175
Query: 545 LDNASVKPVTNQVECHPYLNQKRLKQFC 628
L A+V+P NQVE +P Q+ L++ C
Sbjct: 176 LSLAAVRPAVNQVEVNPMWQQRTLREVC 203
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 135 bits (327), Expect = 7e-31
Identities = 81/201 (40%), Positives = 110/201 (54%), Gaps = 4/201 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKD-AIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+ G IP+ G GT++ E+ V D A++ GYRHID A VY NE+ +G A+KT + +
Sbjct: 36 LNTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLPK 95
Query: 230 GVVKREDLFITSKLWNTFHRPD-LVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
+KRED+FITSKL + + + V + SL NL DYLDLYLIHWP +
Sbjct: 96 YNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRWKW 155
Query: 407 TDADGKIQFSDVDY-VDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL-DNASVKPVTNQ 580
+V Y +W AL L G +RS+GVSN+ K L+ +L D + P NQ
Sbjct: 156 LFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKGIVPAVNQ 215
Query: 581 VECHPYLNQKRLKQFCEDRDI 643
VE HPY Q L ++C I
Sbjct: 216 VEWHPYYYQPELLEYCRQHGI 236
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 134 bits (323), Expect = 2e-30
Identities = 77/193 (39%), Positives = 114/193 (59%), Gaps = 7/193 (3%)
Frame = +2
Query: 71 IPVIGIGTWK---SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVV- 238
+P IG+GT + E T A+ AI++GYRH D A +Y E V EA+ ++ G+V
Sbjct: 18 MPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVA 77
Query: 239 KREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 415
R D+F+TSKLW + H +V A E +LRNL +DY+DL L+HWP FP
Sbjct: 78 SRADVFVTSKLWCSDLHAGRVVPAARE-TLRNLGMDYVDLLLVHWPATVAPGSYDFPFPK 136
Query: 416 DGKIQFSDVDYVDTWKALEPLVCH--GLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+ D++ V W+ +E CH GL R++GVSNF++K+L+++L A V+P NQVE
Sbjct: 137 EEMAPAFDMEGV--WRGMEE--CHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEM 192
Query: 590 HPYLNQKRLKQFC 628
+P Q+ L++ C
Sbjct: 193 NPMWQQRTLREVC 205
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 133 bits (321), Expect = 4e-30
Identities = 70/198 (35%), Positives = 115/198 (58%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+N K+P IG GT+K + G+ T +AVK A+++GYRH+DCA +Y N+ V + IK
Sbjct: 16 LANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLSVSQGIKLS--- 72
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V R+++FITSK+WN + + A L++L+++YLDL LIHWP D
Sbjct: 73 -GVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKD----- 126
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+ +V+ TWKA+E G ++++G+SNF ++ + +A + P+ NQ+E
Sbjct: 127 ------NWQEVN-AQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLEF 179
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP Q + ++C+ +I
Sbjct: 180 HPGYLQPEIVEYCQKNNI 197
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 133 bits (321), Expect = 4e-30
Identities = 75/198 (37%), Positives = 109/198 (55%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
+P L G+ IPV+G GT+K P + AV A+++GYRHID A +YGNE EVG A++
Sbjct: 16 IPTFMLPTGSPIPVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAALEA 75
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
G+ REDLFIT+K+ N+ H PD ++ SL +L DY+DL L+HWP
Sbjct: 76 ---SGIA-REDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP-------- 123
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
PT G D W ALE G R++G+SN+ + ++ + + A+V P
Sbjct: 124 -LPTLYGG-------DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVL 175
Query: 578 QVECHPYLNQKRLKQFCE 631
QVE HP+ L+ + +
Sbjct: 176 QVESHPFFPNADLRAYAQ 193
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 132 bits (319), Expect = 7e-30
Identities = 75/202 (37%), Positives = 106/202 (52%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
VP+ G IP IG GT++ + + V +A+ IGY HID A VY NE+++ + I
Sbjct: 13 VPILNFREGGSIPQIGYGTYELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIAKVIHN 72
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
+KREDLFITSK+ + + A++ L LNI YLD LIHWP K
Sbjct: 73 PAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSK---- 126
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
P + Q ++TWKAL L G+++ +GVSNFN LQ +++ + KP N
Sbjct: 127 -LPPNDPKNAQIR----LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMN 181
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
Q E HP K+ +FC+ I
Sbjct: 182 QFEIHPLCFNKKTIEFCQKNGI 203
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 132 bits (319), Expect = 7e-30
Identities = 74/194 (38%), Positives = 115/194 (59%), Gaps = 1/194 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG +P++G+GT+ + E+T ++ A+D GYRHID A Y NE +GE++KT +E
Sbjct: 10 LNNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFKE 69
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G R+DLFI SK++ ++ + +++ SL+ L +DY+DLY +H+P + +
Sbjct: 70 GKYSRKDLFIVSKVFP--NKGINMLESVKKSLKELQLDYVDLYYLHFPLGFLSE------ 121
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
K +F + W LE GL +S+GVSNFN L +L A VKPV+NQVE
Sbjct: 122 ----KEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEV 177
Query: 590 HPYLNQKRLKQFCE 631
++ QK L +FC+
Sbjct: 178 SVFIQQKNLIKFCQ 191
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 132 bits (318), Expect = 9e-30
Identities = 74/200 (37%), Positives = 114/200 (57%), Gaps = 3/200 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
LS+G +P+IG GT+K + E V Q V +++++G+R ID A Y NE+++G A+K + +
Sbjct: 10 LSSGYDMPLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLLPK 69
Query: 230 GVVKREDLFITSKLWNTFH-RPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
++R D+FIT+KL + + P + ++ SL+ N Y+DLYLIHWP A + P
Sbjct: 70 YNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATR-----IP 124
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA-SVKPVTNQV 583
+ TW L L G +RS+GVSNF K LQ +L N + P NQV
Sbjct: 125 ETSTNNPSLR----AKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQV 180
Query: 584 ECHPYLNQKRLKQFCEDRDI 643
E HP+ Q+ L ++C ++ I
Sbjct: 181 ELHPHYRQEELIKYCNEKGI 200
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 132 bits (318), Expect = 9e-30
Identities = 82/198 (41%), Positives = 111/198 (56%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L IP IG+G ++ E + AV+ AI++GYR D A VY NE VG+AI +
Sbjct: 11 LPGNETIPYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----D 66
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V RE+LFI+SK+WN D A E +LRNL +DYLDLYLIHWP A K
Sbjct: 67 SAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK-------- 118
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
Y D+W+A+E L L++S+GV+NF L +L A+ KPV NQVE
Sbjct: 119 ------------YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVET 166
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP L Q L+++ +++I
Sbjct: 167 HPLLPQNDLRKYLAEQNI 184
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 132 bits (318), Expect = 9e-30
Identities = 74/193 (38%), Positives = 104/193 (53%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M PV L++G +IP IG+GTW +V AV +A++ GYRHID A YGNEK VG
Sbjct: 1 MALSPVIELNDGHRIPQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNG 60
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
I++ + R +LFIT+KL F D L+ SL+ L +DY+DL LIHWP ++
Sbjct: 61 IRS----SGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRD 116
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
+++ TWK E L G VRS+GVSNF L+R++ V P
Sbjct: 117 ------------------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVP 158
Query: 569 VTNQVECHPYLNQ 607
NQ++ P + +
Sbjct: 159 AVNQIQVSPAITR 171
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 131 bits (317), Expect = 1e-29
Identities = 70/197 (35%), Positives = 110/197 (55%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
MT PV +GA+IP +G G W+ + V+ AI+IGYR ID A++Y NE +GE
Sbjct: 1 MTDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG 60
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
++ + R+++F+T+K+WN R ++E SL+ + ++ LDL LIHWP
Sbjct: 61 LRA----SGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP----- 111
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
+ D+ Y++TWKA + + GL+RS+G SNFN+ L+RI+ P
Sbjct: 112 ------------VPSQDL-YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAP 158
Query: 569 VTNQVECHPYLNQKRLK 619
V NQ+E +P L Q ++
Sbjct: 159 VLNQIELNPMLQQPEMR 175
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 131 bits (316), Expect = 2e-29
Identities = 77/211 (36%), Positives = 112/211 (53%), Gaps = 13/211 (6%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M + P +L+NG I +G G +K P + V A++ GYRH D A +YGNE VG+A
Sbjct: 1 MKNSPRLSLNNGVLIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKA 60
Query: 209 IKTKIQ-----------EGV--VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYL 349
I E + REDLF+T+K+WN H D A + S+ NL ++Y+
Sbjct: 61 IGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYV 120
Query: 350 DLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSK 529
DLYLIHWP A + +F ++++A+E L G +R++GVSNF
Sbjct: 121 DLYLIHWPCARR---GLF---------------TESYRAMETLYREGRIRAIGVSNFQPA 162
Query: 530 QLQRILDNASVKPVTNQVECHPYLNQKRLKQ 622
L+ +L+ A V P NQ+E HP+L Q L+Q
Sbjct: 163 HLEHLLETAEVVPAVNQIELHPWLQQDELRQ 193
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 131 bits (316), Expect = 2e-29
Identities = 77/203 (37%), Positives = 107/203 (52%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
++P TL+NG KIP +G G ++ P E + V+DA++ GYRHID A Y NE VG AI
Sbjct: 8 TIPQLTLNNGVKIPQLGFGVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGAAIS 67
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
+ RED+FIT+KL N A + S + L ++++DLYLIHW
Sbjct: 68 A----SGIPREDIFITTKLRN--GEQGNAHEAFQNSRKALGVEFVDLYLIHW-------- 113
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
P + G Y + WKA+E L + +R++GVSNF + L +L A V P
Sbjct: 114 ---PVPSQGL-------YTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAV 163
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQVE HP Q+ L C + I
Sbjct: 164 NQVEIHPTFQQQELAAKCRELGI 186
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 131 bits (316), Expect = 2e-29
Identities = 71/192 (36%), Positives = 114/192 (59%), Gaps = 1/192 (0%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDA-IDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRE 247
+P+IGIGTW+ + E+ + V DA GYR ID A VY NE ++G ++ + +KRE
Sbjct: 11 MPLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKRE 70
Query: 248 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 427
D++ITSKL + R ++E SL NL ++YLDL LIHWP + + + A+ K+
Sbjct: 71 DIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSE----NPANKKL 126
Query: 428 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQ 607
+ V++W + ++ G +RS+GVSNF L+ + +++V P NQVE HP+ +Q
Sbjct: 127 R------VESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQ 180
Query: 608 KRLKQFCEDRDI 643
L ++C + +I
Sbjct: 181 DDLVKYCNENNI 192
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 130 bits (315), Expect = 2e-29
Identities = 74/206 (35%), Positives = 107/206 (51%)
Frame = +2
Query: 26 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE 205
++ +P TL +G IP +G GT++ + QA+ +AID GYR ID A+ Y NE VGE
Sbjct: 1 MVNQIPNVTLHDGLTIPKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGE 60
Query: 206 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
A++ RE L ITSKL +H D ++ SL N+DY DLYLIHWP
Sbjct: 61 AVR----RSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPN--- 113
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
D+ YV+ W+AL G +RS+GV NF + L+R+
Sbjct: 114 --------------PIQDI-YVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGEL 158
Query: 566 PVTNQVECHPYLNQKRLKQFCEDRDI 643
P NQ+E HP+ NQ+ +++ ++ I
Sbjct: 159 PTINQIELHPFFNQEDQRKWHQEHQI 184
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 130 bits (315), Expect = 2e-29
Identities = 67/199 (33%), Positives = 117/199 (58%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L NG +IP + +GT+++K ++ AV +A+ +GYR D A Y NEK++G A+KT +
Sbjct: 4 LKNGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPRH 63
Query: 233 VVKREDLFITSKL--WNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
+ ED+++TSK+ +++ + +L+R + SL L+ YLDL L+H+P+ P
Sbjct: 64 NICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPR---------P 114
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
D + + + + DTW ALE L G +RS+GVSN+ ++ + +++P NQ+E
Sbjct: 115 LDTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIE 174
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HP+ +K L+ +C +I
Sbjct: 175 YHPHFQRKVLRAYCNKNEI 193
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 130 bits (314), Expect = 3e-29
Identities = 75/207 (36%), Positives = 114/207 (55%), Gaps = 6/207 (2%)
Frame = +2
Query: 23 LIMTSVPVTTLSNGAKIPVIGIGTW------KSKPGEVTQAVKDAIDIGYRHIDCAFVYG 184
+I + L+NG K+P++G+GT + E+T + +A+D GYR+ D A Y
Sbjct: 7 IINQDIKYVQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYR 66
Query: 185 NEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 364
NE E+G+A + Q+G KRED+FIT+KL+ F ++ ++ SL L Y+DLYLI
Sbjct: 67 NEVEIGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLI 125
Query: 365 HWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 544
W T+ DG + + + W+ LE V G++RS+GV+NFN + + +
Sbjct: 126 QW------SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDL 179
Query: 545 LDNASVKPVTNQVECHPYLNQKRLKQF 625
L A +KPV NQ+E PYL Q L F
Sbjct: 180 LSYAKIKPVVNQIEVTPYLPQIDLINF 206
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 130 bits (314), Expect = 3e-29
Identities = 77/193 (39%), Positives = 105/193 (54%), Gaps = 2/193 (1%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIDCAFVYGNEKEVGEAI 211
+V + LSN K+P++G G ++ +V Q+V +AI GYR ID A VYGNE VGEA+
Sbjct: 5 TVEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAV 64
Query: 212 KTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
+ I EG+ RE+LFITSKLW D+ +E SL+ ++Y DLYL+H QA +
Sbjct: 65 REAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH--QAMR- 121
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
DY W+ALE G ++++GVSNF L + VKP
Sbjct: 122 ------------------DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKP 163
Query: 569 VTNQVECHPYLNQ 607
+ NQVE HPY Q
Sbjct: 164 MVNQVELHPYFAQ 176
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 130 bits (314), Expect = 3e-29
Identities = 80/193 (41%), Positives = 109/193 (56%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M VP L+NG ++P +G+GT+ K + V AI +G+R ID A YGNEKEVGE
Sbjct: 26 MNKVPTVKLNNGMEMPQLGVGTFLVKDN-AAERVCHAIKVGFRLIDTAQGYGNEKEVGEG 84
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
I + G+ +RE LFIT+K+ R VR +L+ SL +L DY+DL LIHWP
Sbjct: 85 I---CRSGIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP----- 135
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
G I+ +TW+ LE V G +RS+GVSNFN L +L+ A ++P
Sbjct: 136 --------VKGHIK-------ETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRP 180
Query: 569 VTNQVECHPYLNQ 607
V NQ+E PY+ Q
Sbjct: 181 VVNQIEIEPYMTQ 193
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 130 bits (313), Expect = 4e-29
Identities = 74/207 (35%), Positives = 113/207 (54%), Gaps = 2/207 (0%)
Frame = +2
Query: 29 MTSVPVT-TLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIDCAFVYGNEKEVG 202
M+S+ T L NG IP IG+GTW+ GE T AV A+ GYRHID A+ Y NE+ VG
Sbjct: 1 MSSLHETFVLENGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVG 60
Query: 203 EAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY 382
+A++ + + R D+F+TSKL D + ++ N ++ LDLYLIH P +
Sbjct: 61 KAVR----DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPW 116
Query: 383 KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV 562
E A + + ++ WKA+E + G R++GVSNF+ L+ +++NA +
Sbjct: 117 SEKGADYTKEN-----------IEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKI 165
Query: 563 KPVTNQVECHPYLNQKRLKQFCEDRDI 643
KP+ NQ+ Q+ + FC+D I
Sbjct: 166 KPMVNQIRYFIGHTQEDVTAFCQDNGI 192
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 129 bits (311), Expect = 6e-29
Identities = 71/195 (36%), Positives = 113/195 (57%)
Frame = +2
Query: 59 NGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVV 238
+G ++P+IG+G +++ P E T AV++A+ +GYRHID A YGNE+EVGE I+ + G+
Sbjct: 25 SGVEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIR---RAGIA 81
Query: 239 KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 418
R+++FI +K+W + + D A + S L +D +DL L+H P P+ D
Sbjct: 82 -RDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQP---------LPSAFD 131
Query: 419 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPY 598
+ ++ALE L+ G VR++GVSNF + L R+L S+ P NQ+E HPY
Sbjct: 132 RTL--------GAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPY 183
Query: 599 LNQKRLKQFCEDRDI 643
Q+ L++ + I
Sbjct: 184 FQQRALQRLHAEHGI 198
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 128 bits (310), Expect = 9e-29
Identities = 72/198 (36%), Positives = 109/198 (55%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+N KIP+ G GT++ P + QAV A + GYR ID A Y NE++VGEA+K
Sbjct: 5 TLNNDVKIPIFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVKA---- 60
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+ R+++FIT+K + + L+ SLR + +DY DL LIHWP +
Sbjct: 61 SGLNRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD-------- 110
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+DTW ALE G R++G+SNFNS+Q ++ +SV+P+ +Q+E
Sbjct: 111 -------------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIET 157
Query: 590 HPYLNQKRLKQFCEDRDI 643
H +L Q ++ +F E +I
Sbjct: 158 HLFLQQWKMHEFLEKENI 175
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 128 bits (310), Expect = 9e-29
Identities = 71/202 (35%), Positives = 112/202 (55%), Gaps = 1/202 (0%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
P L+NG IP +G+G WK+ E Q VK+AI Y ID A YGNE VG+ I+
Sbjct: 11 PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDG 70
Query: 221 IQEGVVKREDLFITSKLWNTFHRP-DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
+ KR+ +F+T+K++N D +R A+ L+ L +Y+DL L+HWP K
Sbjct: 71 FKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVNDK---- 126
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
Y ++W+ALE + G +++GV NFN +++ +LD+A +KP N
Sbjct: 127 ----------------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAIN 170
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
Q+E +P ++Q ++ +FC + DI
Sbjct: 171 QIEFNPLIHQPKIVKFCRENDI 192
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 128 bits (308), Expect = 1e-28
Identities = 77/203 (37%), Positives = 108/203 (53%), Gaps = 8/203 (3%)
Frame = +2
Query: 59 NGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI--QEG 232
N K+P++GIGT+K ++ +K ++ GYR ID A +Y NE+ +G+ + + +G
Sbjct: 23 NPIKMPMLGIGTFKLN--DIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDG 80
Query: 233 V----VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 400
+ +KREDLFITSK + A E SL+ L +DYLD YLIHWP
Sbjct: 81 LDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGV------- 133
Query: 401 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKPVT 574
DG + + TW+ALE L VRS+GVSN+ L +L N +KP
Sbjct: 134 --KGLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAI 191
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQVE HP QK L +FC++ I
Sbjct: 192 NQVEFHPLNFQKDLLEFCKNNKI 214
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 128 bits (308), Expect = 1e-28
Identities = 87/204 (42%), Positives = 115/204 (56%), Gaps = 10/204 (4%)
Frame = +2
Query: 62 GAKIPV--IGIGT--WKSKPGEVTQ----AVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
G KIPV G+GT +K + GE+ + +VK+A+ G+ HIDCA VYGNE+EVG A+K
Sbjct: 7 GPKIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALK- 65
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
E V R LFITSK+ H D + AL SLR L DYLDLYL+H P + E
Sbjct: 66 ---EANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK-- 117
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
KI S+ WKA+E + GLV S+GVSNF L+ +L +++ P N
Sbjct: 118 --------KIPISE-----GWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVN 164
Query: 578 QVECHP--YLNQKRLKQFCEDRDI 643
Q+E HP Y K L +FC+ + I
Sbjct: 165 QIEFHPQVYKAAKPLVEFCQSKGI 188
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 127 bits (307), Expect = 2e-28
Identities = 78/206 (37%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE 205
MT P TL++G IP IG GT++ G QAVK+A+ IGYRHID A Y NE EVG+
Sbjct: 1 MTKTPTITLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQ 60
Query: 206 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
AIK + + R+ +++TSKLW + D A++ SL L +DY+DLYLIH P
Sbjct: 61 AIK----DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQP---- 112
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
+ DV W+A+E G ++S+GVSN Q+ +
Sbjct: 113 ---------------YGDVP--GAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETI 155
Query: 566 PVTNQVECHPYLNQKRLKQFCEDRDI 643
P NQVE +PY Q+ L+Q +D+
Sbjct: 156 PAVNQVEFNPYFQQQPLRQLLAAQDV 181
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 127 bits (306), Expect = 3e-28
Identities = 74/201 (36%), Positives = 110/201 (54%), Gaps = 1/201 (0%)
Frame = +2
Query: 44 VTTLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
V TLSNG K+P G+G+ + + EVT ++ A+D+GYRHID A +Y NE+ +G A+KT
Sbjct: 9 VITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTI 68
Query: 221 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 400
EG KRED+F+ +K + ++ L+ L +DY+DL LIH P A DD
Sbjct: 69 FGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAPSDD-- 124
Query: 401 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQ 580
Q++ W E + GL + LGVSNFN + + +L +KP+ NQ
Sbjct: 125 -------YQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQ 177
Query: 581 VECHPYLNQKRLKQFCEDRDI 643
+E H + QK L +F + +I
Sbjct: 178 IELHVFNQQKNLVEFLKKVNI 198
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 127 bits (306), Expect = 3e-28
Identities = 78/212 (36%), Positives = 118/212 (55%), Gaps = 9/212 (4%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGT---WKSKPG------EVTQAVKDAIDIGYRHIDCAFVYGN 187
+ P L++ IP++G GT W + G E+ +A+K AI +GYRH+D A VYG
Sbjct: 8 NTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGT 67
Query: 188 EKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIH 367
E E+G AIK E + RE+LF+T+K+ + A++ SLR L ++Y+DLYLIH
Sbjct: 68 EAELGVAIK----ESGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIH 120
Query: 368 WPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL 547
P F +DG++Q W A+E + G +++GVSN++ L+ L
Sbjct: 121 SP---------FFAKSDGELQ-------QAWAAMEKVQQAGKAKAIGVSNYHQSHLEATL 164
Query: 548 DNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
A + PV NQ+E HPYL Q+ L +F ++DI
Sbjct: 165 KTAVIAPVINQIEHHPYLQQEELLRFQREKDI 196
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 126 bits (305), Expect = 3e-28
Identities = 72/203 (35%), Positives = 113/203 (55%), Gaps = 1/203 (0%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
VP L +G ++P++G+GT+K + E + Q+V A+ GYR D A VYGNE +G+ +K
Sbjct: 3 VPSVRLMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLK 62
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
+ + + RED+FI SKL + H G L SL L+ +Y+DLYLIHWP +
Sbjct: 63 ELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGM----E 117
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
+ P D+ + S+ +W LE G +++GVSN+ +K ++ +L + V P
Sbjct: 118 GLDPEDS----RHSEYR-AQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAV 172
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
Q+EC P L Q+ L+ C + I
Sbjct: 173 LQIECQPKLIQRELRDLCMETGI 195
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 126 bits (305), Expect = 3e-28
Identities = 70/167 (41%), Positives = 94/167 (56%), Gaps = 1/167 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG IP+ G GT+K K E +V+ A+ GYRHID A Y NEK V AIK ++E
Sbjct: 10 LNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAIKDFMEE 69
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
KRED+F+TSK W T D A E ++ + +DYLDLYL+HWP +Y DD T
Sbjct: 70 SQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFDDDWENT 129
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 550
+ TWKA+ + G V+++GVSNF + L I+D
Sbjct: 130 NRQ------------TWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID 164
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 126 bits (305), Expect = 3e-28
Identities = 77/205 (37%), Positives = 108/205 (52%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
+T TLS+G KIP G+G + QAV A++ GYR ID A Y NEK VGEA
Sbjct: 1 LTLSSTRTLSDGYKIPRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEA 60
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
++ E V R ++++ +K+++T H + A + SL L +DY+DLYLIH
Sbjct: 61 LR----ESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIH------- 109
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
FP A V +W+A+ L GL RS+GVSNFN L+ + ++ + P
Sbjct: 110 ----FPVPA---------GVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPP 156
Query: 569 VTNQVECHPYLNQKRLKQFCEDRDI 643
V NQ+E HPYL + L FC I
Sbjct: 157 VVNQIEVHPYLQMEELVDFCRKHSI 181
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 126 bits (305), Expect = 3e-28
Identities = 79/202 (39%), Positives = 113/202 (55%), Gaps = 10/202 (4%)
Frame = +2
Query: 68 KIPVIGIGTWKSKP-----GEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
+IP G+GT++ P G V +V A+ IGYRHID A YG V I I+
Sbjct: 15 RIPARGLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAAIRAS 73
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY-KEDDAIFPT 409
V RED+F+ +KL N FH P+ V + +SL+NL + Y+ P AY K ++
Sbjct: 74 GVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYV-------PYAYTKGENYSTVR 126
Query: 410 DADGK----IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
DGK I+ S + TWKA+E LV G + +GVSNF++ +L+R+L + PV N
Sbjct: 127 KPDGKPVVDIELSRA-FDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVN 185
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVE +PY QK+L +FC + +I
Sbjct: 186 QVELNPYFPQKQLLRFCHEHEI 207
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 125 bits (302), Expect = 8e-28
Identities = 75/204 (36%), Positives = 112/204 (54%), Gaps = 1/204 (0%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAI-DIGYRHIDCAFVYGNEKEVGEAI 211
S P L NG IP++G+GT G +AV A+ + G RHID A YG E+ +G+A+
Sbjct: 12 SCPAVPLHNGLNIPILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGCEEALGKAV 70
Query: 212 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
E V+RE+L++T+KLW + + A S L +DYLDLYL+HWP
Sbjct: 71 T----ESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWP------ 120
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
D++ P + +++ ++TW+ALE L GL R++GVSNF L + D+ + P
Sbjct: 121 DSMVPGRSSQEVR------LETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPH 174
Query: 572 TNQVECHPYLNQKRLKQFCEDRDI 643
NQVE HP+ +L + C +I
Sbjct: 175 VNQVEFHPFQQPMKLVEHCRKENI 198
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 125 bits (302), Expect = 8e-28
Identities = 70/199 (35%), Positives = 115/199 (57%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L++G IP +G GT+K V A+ A+ GYR D A Y NEKE+GEA+K + +
Sbjct: 15 LNSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPKH 74
Query: 233 VVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+ R D+F+TSK + + + + RG +E SL++L DY+D+YL+H+P+ P
Sbjct: 75 GLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPK---------PN 125
Query: 410 DADGKIQFSDVDYVD-TWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
D+D ++ +Y ++ LE G VRS+GVSN+ L+ + A V P NQ+E
Sbjct: 126 DSDND-DVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLE 184
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HP+ + L+++C++++I
Sbjct: 185 YHPHFARIPLQKYCKEKNI 203
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 124 bits (300), Expect = 1e-27
Identities = 71/198 (35%), Positives = 112/198 (56%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG ++P G G +K + + A++ A+D+GYR D A Y NEKE+G+ +
Sbjct: 11 LNNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS--- 67
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+KR++ F+T+K+WNT D A E S + L +D +DLYL+HWP K+D
Sbjct: 68 -GLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD------ 117
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+ +TW+A+E L GLVR++GVSNF + L R+ +A+V PV +Q+E
Sbjct: 118 -----------TFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLET 166
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP+ + L ++ E+ I
Sbjct: 167 HPHFPNQLLHRYLEELHI 184
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 124 bits (300), Expect = 1e-27
Identities = 78/199 (39%), Positives = 111/199 (55%), Gaps = 2/199 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPG--EVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQ 226
L NG+ +P IG+GT++ G +V VK AI GYRHID A YGNE+ +G+AIK
Sbjct: 10 LVNGSTLPAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDAIK---- 65
Query: 227 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
E + R++L ++ W H P V AL++SL L ++Y+ P AY P
Sbjct: 66 ESGISRDEL---AQPW---HEPKDVERALDLSLEALGLEYV-------PHAYLPG----P 108
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
+ D + Y +TW+A+E LV G +++G+SNFN + +RIL+ A ++P NQVE
Sbjct: 109 NNVDYE---RSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVE 165
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HPY Q L FCE I
Sbjct: 166 AHPYFPQHELLAFCEKEHI 184
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 124 bits (299), Expect = 2e-27
Identities = 74/198 (37%), Positives = 108/198 (54%), Gaps = 1/198 (0%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M+ + S +P +G GTW+ + G V+ A++IGYRHID A +YGNE++VG A
Sbjct: 1 MSKLVPAVRSGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAA 60
Query: 209 IKTKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
I+ VKR+++F+T+K+W + F DL R A E SL L +D +DL L+HWP+
Sbjct: 61 IR----NSGVKRDEIFLTTKVWIDQFADGDLQRSA-EKSLEKLGVDQVDLLLLHWPK--- 112
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
+V +T KAL + G R++G+SNF S QL+ +
Sbjct: 113 ----------------PEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAP 156
Query: 566 PVTNQVECHPYLNQKRLK 619
T+QVE HPYL+ K LK
Sbjct: 157 IATDQVEYHPYLSLKTLK 174
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 124 bits (299), Expect = 2e-27
Identities = 69/195 (35%), Positives = 110/195 (56%), Gaps = 1/195 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG IP + GTW+ GE T QAV+ A+ GYRHID A Y NE VG+AI+ +
Sbjct: 10 LANGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQAIR----D 65
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+ RE +F+T+KL + SL+NL +DY+DLYL+H P +P
Sbjct: 66 SGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP---------WPW 116
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
G++ D +D W+A+E + G +++GVSNF + L+ IL+ A++ P+ NQ++
Sbjct: 117 GQVGRVY--DEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQY 174
Query: 590 HPYLNQKRLKQFCED 634
+ + ++ +F E+
Sbjct: 175 YLGFTEPKITKFSEE 189
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 124 bits (299), Expect = 2e-27
Identities = 71/195 (36%), Positives = 103/195 (52%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
+P +L++G IPV+G+G + E ++V A++ GYR ID A VYGNE VG A+
Sbjct: 11 IPSVSLNDGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRAVNA 70
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
+ RE++++T+KL + A SL L +DY+DLYLIHW
Sbjct: 71 ----SGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW--------- 117
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
P GK Y+D+W L G+ RS+GV NFN++ L I+D + P N
Sbjct: 118 --PAGDHGK-------YIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAIN 168
Query: 578 QVECHPYLNQKRLKQ 622
Q+E HP LNQ L++
Sbjct: 169 QIELHPLLNQAELRE 183
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 124 bits (299), Expect = 2e-27
Identities = 73/202 (36%), Positives = 112/202 (55%), Gaps = 1/202 (0%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAI 211
+VP L +GA+IP+IG+G ++S+PG E A+ ++ +GYRHID A +YGNE++VG A+
Sbjct: 4 NVPTKILPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVGRAV 63
Query: 212 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
+ + + RE++F+T+KL+ T A + S L I Y+ LYL+H P KE
Sbjct: 64 R----DSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAPGPPKE- 118
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
DTW+A+E L +R +GVSNFN L + A +KP
Sbjct: 119 ------------------RADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPA 160
Query: 572 TNQVECHPYLNQKRLKQFCEDR 637
NQVE HP++ ++ L + + R
Sbjct: 161 VNQVELHPWMMRQSLVNYQDGR 182
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 124 bits (299), Expect = 2e-27
Identities = 81/205 (39%), Positives = 107/205 (52%), Gaps = 1/205 (0%)
Frame = +2
Query: 32 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAI 211
T TL+NG IP IG G + K E V A+D GYRHID A VYGNE G+AI
Sbjct: 6 TESTTVTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAI 65
Query: 212 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
++ VKR D+F+TSKL N R A+ SL +L Y+DL+LI P
Sbjct: 66 VDWCEKNNVKRTDIFLTSKLANCSDYYS-TRAAIRSSLHHLG-TYIDLFLIQSP------ 117
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI-LDNASVKP 568
A GK + +WKA+E V G +RS+GVSN+ K LQ + N P
Sbjct: 118 -------AGGK-----KSRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYP 165
Query: 569 VTNQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HP+L+Q + ++C+ DI
Sbjct: 166 CVNQIELHPFLSQDDIVKYCQSHDI 190
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 124 bits (298), Expect = 2e-27
Identities = 76/206 (36%), Positives = 106/206 (51%)
Frame = +2
Query: 26 IMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE 205
I ++P L +G IP +G GT+ K + + A+ GYR +D AF Y NE VG
Sbjct: 18 IEKNIPDLILHDGHSIPALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGA 77
Query: 206 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
A++ Q G++ R+++FITSKL H D +E SL + DYLDLYLIHWP +
Sbjct: 78 AVR---QSGLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWPNPQQ 133
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
G Y++ W+AL G +RS+GVSNF K ++ + V
Sbjct: 134 -----------GL-------YIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVI 175
Query: 566 PVTNQVECHPYLNQKRLKQFCEDRDI 643
PV NQVE HPY NQ + + E + I
Sbjct: 176 PVINQVELHPYFNQAEQRAYDESQQI 201
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 124 bits (298), Expect = 2e-27
Identities = 60/110 (54%), Positives = 72/110 (65%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
S TL +GAK+P+ G GTWK+ E QAV A+ GYRHIDCA VY NE VG AI
Sbjct: 2 STNTATLQSGAKMPLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAIS 61
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 364
I GVVKREDLFITSK+WNT H D V + SL++ +DY DL+L+
Sbjct: 62 KAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
Score = 42.3 bits (95), Expect = 0.010
Identities = 19/48 (39%), Positives = 28/48 (58%)
Frame = +2
Query: 491 LVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQKRLKQFCED 634
LVR +GVSN++ L L+ A +KP NQ E H Y + +L+ C +
Sbjct: 110 LVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRDVCRE 157
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 124 bits (298), Expect = 2e-27
Identities = 71/192 (36%), Positives = 102/192 (53%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
P+ L+NG K+P +G+G + + E A+ AI GYR ID A Y NE +VGE I+
Sbjct: 6 PLINLNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEGIR-- 63
Query: 221 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 400
V R ++F+T+KL+N + + A + SL L +DY+DLYL+HWP
Sbjct: 64 --NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP--------- 112
Query: 401 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQ 580
D + IQ +WKA E ++ G R++GV NF QL ++ + V P NQ
Sbjct: 113 -TKDWNATIQ--------SWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQ 163
Query: 581 VECHPYLNQKRL 616
+E HPY QK L
Sbjct: 164 IELHPYFAQKPL 175
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 123 bits (297), Expect = 3e-27
Identities = 79/224 (35%), Positives = 115/224 (51%), Gaps = 27/224 (12%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L +G KIP +G+GTW+S V ++ GYRHID A+ YG+++EVG+ IK + G
Sbjct: 18 LLSGHKIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAG 77
Query: 233 VVKREDLFIT----------------SKLWN-----------TFHRPDLVRGALEVSLRN 331
+ +R DLF+T S L N T P+ VR AL+ +L+
Sbjct: 78 L-ERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPALQNTLKE 136
Query: 332 LNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGV 511
L ++YLDLYLIHWP +E + P D D D W+ +E L LVR++GV
Sbjct: 137 LQLEYLDLYLIHWPIRLREGASKPPKAGD----VLDFDMEGVWREMENLSKDSLVRNIGV 192
Query: 512 SNFNSKQLQRILDNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
NF +L ++L A + P Q+E HP R+ +FC+ +I
Sbjct: 193 CNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEI 236
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 122 bits (295), Expect = 6e-27
Identities = 72/199 (36%), Positives = 112/199 (56%), Gaps = 1/199 (0%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKP-GEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQ 226
TL+NG K+P +G G ++ + Q V+D +++GYR +D A +YGNE+ VG+AIK
Sbjct: 6 TLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAIK---- 61
Query: 227 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
V RED+FITSK+W + D A + S++ L +DY+DLYLIH P Y
Sbjct: 62 HSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKP--YN------- 112
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
DY TW+ALE L G +R++GVS+F +++L ++ VKP NQ+E
Sbjct: 113 ------------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIE 160
Query: 587 CHPYLNQKRLKQFCEDRDI 643
+ + + + +Q+ E +
Sbjct: 161 TNVWNQEWKSQQYMEKEGV 179
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 122 bits (295), Expect = 6e-27
Identities = 73/193 (37%), Positives = 101/193 (52%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
T +NGA IP +G GTW+ + + + V A+ GYRHID A +YGNE VG+ K Q
Sbjct: 5 TQANGADIPKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWK---QS 61
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G VKRED F+T+K+W R ++ +++ SL L DY+DL L+HWP
Sbjct: 62 G-VKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWP------------ 108
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+V +T KA+ + G VR +GVSNF L ++ V NQVE
Sbjct: 109 -------VPEVPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEY 161
Query: 590 HPYLNQKRLKQFC 628
HPYL+Q + C
Sbjct: 162 HPYLDQNAVLTAC 174
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 122 bits (295), Expect = 6e-27
Identities = 70/202 (34%), Positives = 112/202 (55%), Gaps = 5/202 (2%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE- 229
LSNG KIP I +GT+ + + V + + GYRH D A +YGNEKEVG+ I + E
Sbjct: 8 LSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNED 67
Query: 230 -GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLN-IDYLDLYLIHWPQAYKEDDAIF 403
G KRE++F T+KLWN+ + + A+ L ++ + Y+DL LIH P
Sbjct: 68 PGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL--------- 118
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKPVTN 577
K++ ++TW+A++ V GLV+S+GVSN+ K + +L+ KPV N
Sbjct: 119 ---EGSKLR------LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVN 169
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
Q+E P++ ++ L +C+ + +
Sbjct: 170 QIEISPWIMRQELADYCKSKGL 191
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 122 bits (294), Expect = 7e-27
Identities = 78/199 (39%), Positives = 113/199 (56%), Gaps = 14/199 (7%)
Frame = +2
Query: 29 MTSVPVTTL-SNGAKIPVIGIGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAFVYGNEKE 196
M S+P TL S G IP++G+ T + P E + ++ AI++GYRH DC Y +EK
Sbjct: 1 MISIPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKP 60
Query: 197 VGEAIKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLR---------NLNIDY 346
+GEAIK ++ G++K R++LFITSKLW + D V AL+ +L+ NL +DY
Sbjct: 61 LGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDY 120
Query: 347 LDLYLIHWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNS 526
LDLYLIHW +DG + +D WKA+E L +++GVSNF+
Sbjct: 121 LDLYLIHW--------------SDGHLP---IDLGSVWKAMEDFQKLSLTKAIGVSNFSC 163
Query: 527 KQLQRILDNASVKPVTNQV 583
+L+ +L AS+ P NQV
Sbjct: 164 NKLEELLQTASILPAVNQV 182
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 122 bits (293), Expect = 1e-26
Identities = 70/203 (34%), Positives = 101/203 (49%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
+VP L +G IP +G+G + V V+ A++ GYRHID A Y NE VG A+
Sbjct: 10 NVPDIALKDGHSIPQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVGRALA 69
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
KRE L++T+KL ++ D A + SL+ L +DY+D+Y+IHWP +
Sbjct: 70 ASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF---- 125
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
D DTWKA L G+ R+LGV NF L+R+ + P
Sbjct: 126 --------------DWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAV 171
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HP Q+ + FC++ I
Sbjct: 172 NQIELHPTWQQREVVAFCKEHGI 194
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 122 bits (293), Expect = 1e-26
Identities = 81/209 (38%), Positives = 112/209 (53%), Gaps = 4/209 (1%)
Frame = +2
Query: 29 MTSVPVTT---LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKE 196
MT +T L++G ++PV+G GT+ + + A++ A D GYR D A +Y NE
Sbjct: 1 MTPTEITATRKLADGRQMPVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDI 60
Query: 197 VGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQ 376
+G AI+ Q G+ RE LF+TSK+ D A+E SL+ L DYLDL LIHWP
Sbjct: 61 LGPAIQ---QLGL-PREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWP- 115
Query: 377 AYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA 556
+E + DTW+ALE L G V+S+GVSN+ L+ + A
Sbjct: 116 -VRE------------------HFFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKA 156
Query: 557 SVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
PV NQVE HPYLNQ+ L + ++ DI
Sbjct: 157 KEMPVVNQVEYHPYLNQQALADYDQEHDI 185
>UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo
sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo
sapiens (Human)
Length = 188
Score = 72.5 bits (170), Expect(2) = 2e-26
Identities = 35/61 (57%), Positives = 44/61 (72%)
Frame = +2
Query: 137 AIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALE 316
AI+ G+ HID A VY NE++VG I +G VKRED+F TSKLW+ HRP+LVR ALE
Sbjct: 2 AIEAGFHHIDSAHVYNNEEQVG------IADGSVKREDIFYTSKLWSNSHRPELVRPALE 55
Query: 317 V 319
+
Sbjct: 56 I 56
Score = 69.3 bits (162), Expect(2) = 2e-26
Identities = 35/73 (47%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Frame = +2
Query: 422 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK--PVTNQVECHP 595
+I F VD TW+A+E +S+GVSNFN + L+ IL+ +K PV NQVECHP
Sbjct: 55 EILFDTVDLCATWEAME--------KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHP 106
Query: 596 YLNQKRLKQFCED 634
Y NQ++L FC+D
Sbjct: 107 YFNQRKLLDFCKD 119
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 120 bits (290), Expect = 2e-26
Identities = 51/82 (62%), Positives = 68/82 (82%)
Frame = +2
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
+ P DADGK+QFSDVDY+DTWKA+E L+ G V+S+GVSNFNS+Q+ R+L +KPVTN
Sbjct: 90 LMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTN 149
Query: 578 QVECHPYLNQKRLKQFCEDRDI 643
QVEC+P LNQ++L +FC++ DI
Sbjct: 150 QVECNPSLNQRKLTEFCKNLDI 171
Score = 115 bits (277), Expect = 9e-25
Identities = 56/108 (51%), Positives = 78/108 (72%), Gaps = 2/108 (1%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
P+ L+NG ++PV+G+GTW SK GE +A+K AID GYRHID A+ Y NEKEVGEAI+ K
Sbjct: 6 PMVKLNNGLEMPVLGLGTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGEAIRAK 65
Query: 221 IQEGVVKREDLFITSKL--WNTFHRPDLVRGALEVSLRNLNIDYLDLY 358
I+EGVV REDLF+T+K W+T +L+ + L+ ++DY+D +
Sbjct: 66 IEEGVVCREDLFVTTKFIDWDT---KNLMPYDADGKLQFSDVDYIDTW 110
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 120 bits (290), Expect = 2e-26
Identities = 81/213 (38%), Positives = 110/213 (51%), Gaps = 10/213 (4%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGT---WKSKPGE-----VTQAVKDAIDIGYRHIDCAFVYGNE 190
+VP LSNG +IP IG G+ WK PGE + AV AI+ G+ HID A YG E
Sbjct: 2 TVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTE 61
Query: 191 KEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHW 370
K++GEAIK E V R+D+F+TSK D + ++ L+ L DY DL+LIH
Sbjct: 62 KQIGEAIK----ESGVPRKDIFLTSKTLFGLLADDPIE-SISNQLKTLQTDYFDLFLIHV 116
Query: 371 PQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD 550
P DD + D W LE L GL +++GVSN + +L+ I+
Sbjct: 117 P---PNDDI-------------NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIK 160
Query: 551 NASVKPVTNQVECHPYLNQKR--LKQFCEDRDI 643
A +KP NQ+E HP L + + FC+ DI
Sbjct: 161 VAKIKPHVNQIEFHPLLQEPTPGIVDFCKQHDI 193
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 120 bits (290), Expect = 2e-26
Identities = 72/194 (37%), Positives = 101/194 (52%)
Frame = +2
Query: 62 GAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVK 241
G +P +G+GTW+ + V+ A+ +GYRHID A YGNE++VG + V
Sbjct: 8 GTSVPALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVG----LGMDAAAVD 63
Query: 242 REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADG 421
RED+F+T+KL + VR + SL L DYLDL LIHWP P A
Sbjct: 64 REDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWPNT--------PWMA-- 113
Query: 422 KIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYL 601
+T A+ +V GLVR +GVSNF+ L R D +S T+QV+ HPY
Sbjct: 114 -------SLSETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYW 166
Query: 602 NQKRLKQFCEDRDI 643
+Q++L +C D+
Sbjct: 167 DQRKLLDYCRIHDV 180
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 120 bits (289), Expect = 3e-26
Identities = 67/196 (34%), Positives = 106/196 (54%)
Frame = +2
Query: 56 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGV 235
+NGA+IP IG+GTW+ + V+ A+ +GYRHID A VY NE+EVG+ ++
Sbjct: 6 ANGARIPAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDGVRA----SG 61
Query: 236 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 415
V+R+D+F+T+K+W P+ + +++ SL L + +DL L+HWP
Sbjct: 62 VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPN------------- 108
Query: 416 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHP 595
S V +T AL GL R +GVSNF +++ + + V NQVE HP
Sbjct: 109 ------SHVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHP 162
Query: 596 YLNQKRLKQFCEDRDI 643
YL+Q +++ C+ +
Sbjct: 163 YLDQAKVRAACDQHGL 178
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 120 bits (289), Expect = 3e-26
Identities = 67/193 (34%), Positives = 104/193 (53%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+NG KIP I +GTW EV + V+ A++IGYR D A YGNE VG+ I
Sbjct: 9 LNNGEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKG----IWNS 64
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
++R D+F+T+KL + + A++ +L ++Y+DL LIH PQ + E +
Sbjct: 65 DIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTNDRH 124
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
G + + W+A+E V G VRS+GVSNF + ++ I++N ++ P NQ+E H
Sbjct: 125 FKGNL--------ENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVH 176
Query: 593 PYLNQKRLKQFCE 631
L +C+
Sbjct: 177 IGKVPVELMDYCK 189
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 120 bits (289), Expect = 3e-26
Identities = 67/177 (37%), Positives = 101/177 (57%), Gaps = 8/177 (4%)
Frame = +2
Query: 29 MTSVPVTTLSNGAK----IPVIGIGTWKS---KPGEVTQAVKDAIDIGYRHIDCAFVYGN 187
+T+VP + +G +PV+G GT S +P + + V +AI +GYRH D + Y
Sbjct: 3 LTTVPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQT 62
Query: 188 EKEVGEAIKTKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLI 364
E+ +GEA+ + G+V+ R + F+T+KLW LV A++ SL+NL +DYLDLY+I
Sbjct: 63 EEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYII 122
Query: 365 HWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQL 535
HWP + K FP D D F +D+ W +E GL + +GVSNF+ K+L
Sbjct: 123 HWPVSSKPGKYKFPIDED---DFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176
>UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1;
Aspergillus fumigatus|Rep: Aldehyde reductase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 350
Score = 120 bits (289), Expect = 3e-26
Identities = 71/164 (43%), Positives = 96/164 (58%), Gaps = 7/164 (4%)
Frame = +2
Query: 146 IGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSL 325
+GYRHID A V NE EVG K K+ V RE +F+TSKLWNT H P V AL+ ++
Sbjct: 72 VGYRHIDSAAVGLNEAEVGRGWK-KLG---VPREGIFLTSKLWNTHHHPSHVEEALDKTV 127
Query: 326 RNLNIDYLDLYLI----HWPQAYKEDDAIFPTDADGKIQFS--DVDYVDTWKALEPLVCH 487
++L +YLDLYL+ H Y+ P G +F D+ DTW A E LV
Sbjct: 128 KDLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNA 184
Query: 488 GLVRSLGVSN-FNSKQLQRILDNASVKPVTNQVECHPYLNQKRL 616
G +RSLGVSN F ++++ +L+ A + P NQ+E HPYL Q ++
Sbjct: 185 GKIRSLGVSNLFTIEKMEELLNTADIPPAVNQIEAHPYLLQPKI 228
>UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus
scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus
scrofa (Pig)
Length = 206
Score = 108 bits (259), Expect(2) = 4e-26
Identities = 61/128 (47%), Positives = 74/128 (57%), Gaps = 1/128 (0%)
Frame = +2
Query: 68 KIPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKR 244
KIPV+G+GTW++ PG EVT+AVK AID GYRH D A++Y NE EVG I+ KI EGVV+R
Sbjct: 1 KIPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRR 60
Query: 245 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 424
EDLFI SK YLDL IHWP +K + P D G
Sbjct: 61 EDLFIVSK----------------------KXXYLDLXNIHWPMQFKPGEVDLPVDRSGM 98
Query: 425 IQFSDVDY 448
I S+ D+
Sbjct: 99 IVASNTDF 106
Score = 32.7 bits (71), Expect(2) = 4e-26
Identities = 14/24 (58%), Positives = 16/24 (66%), Gaps = 1/24 (4%)
Frame = +2
Query: 542 ILDNASVK-PVTNQVECHPYLNQK 610
+ N K PVTNQ+E HPYL QK
Sbjct: 100 VASNTDFKXPVTNQIESHPYLTQK 123
>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 293
Score = 120 bits (288), Expect = 4e-26
Identities = 78/201 (38%), Positives = 106/201 (52%), Gaps = 3/201 (1%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-IGYRHIDCAFVYGNEKEVGEAIKTKIQ 226
T+ +G +P GIG W + E QA+ +A D GYRH+D A Y NE + GEA++
Sbjct: 20 TMVDGYAMPRFGIGAWDMRGSECKQALLNAFDKAGYRHVDTARYYRNEADCGEAVR---- 75
Query: 227 EGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIF 403
E V R +LF T+K++ N R A+E SL +DYLDL L+H P
Sbjct: 76 ECSVPRSELFYTTKVYLNEMGGGSKTRLAVEDSLAKAGLDYLDLVLLHAP---------- 125
Query: 404 PTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN-ASVKPVTNQ 580
DG +F +D+W L LV G VRSLGVSNF +Q ++D+ V PV NQ
Sbjct: 126 ----DGGKKFR----LDSWDTLTELVQEGKVRSLGVSNFGPHHIQELIDSKPKVLPVCNQ 177
Query: 581 VECHPYLNQKRLKQFCEDRDI 643
+ECHP+ QK ++ E I
Sbjct: 178 IECHPFFAQKEVRAASEAHSI 198
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 119 bits (286), Expect = 7e-26
Identities = 72/203 (35%), Positives = 105/203 (51%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
+VP +++G P +G+G W+ + +V+ AI+ GYRHID A +YGNE+ VG A+
Sbjct: 7 AVPTLEMNDGKTTPQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVGRAVA 66
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
++ G V+RE+LFIT+KLWN + A S + L +DY+DLYL+HWP + D
Sbjct: 67 DAVKAGDVQREELFITTKLWNADQA--CGKEAFAESQKKLGMDYVDLYLLHWP-CPQADS 123
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
+ D+ +IQ S G S+GV NF + L L A P
Sbjct: 124 FVQAYDSMAEIQQS-----------------GGATSIGVCNFYPEALD-ALKQAGHTPAV 165
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HP +Q + DR I
Sbjct: 166 NQIEIHPGFSQAEQRSDNRDRGI 188
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 119 bits (286), Expect = 7e-26
Identities = 70/192 (36%), Positives = 103/192 (53%), Gaps = 1/192 (0%)
Frame = +2
Query: 71 IPVIGIGTWKSKPG-EVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRE 247
+P++G+G +K+ E A+ A+ GYR +D A Y NE+ VG I + V R+
Sbjct: 1 MPLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVG----CGIAKCGVPRK 56
Query: 248 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 427
DLFIT+K+WN R V GA + SL L +DY+DLYLIHWP G
Sbjct: 57 DLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWP-------------VPG-- 101
Query: 428 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQ 607
+++TWK +E ++ G S+GVSNF + L+ + + + P NQ+ECHP
Sbjct: 102 -----CFLNTWKDMEKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYP 156
Query: 608 KRLKQFCEDRDI 643
K L ++C+ DI
Sbjct: 157 KELIEYCQANDI 168
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 119 bits (286), Expect = 7e-26
Identities = 78/203 (38%), Positives = 111/203 (54%), Gaps = 1/203 (0%)
Frame = +2
Query: 38 VPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-IGYRHIDCAFVYGNEKEVGEAIK 214
+P T LSN ++P+IG+GT S G AV +I GYR ID A YG EK++G A+K
Sbjct: 2 IPTTVLSNNVEMPLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVK 60
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
V RE++F+++KLW D V A + S L DYLD+Y+IH PQ D
Sbjct: 61 NCS----VPREEMFLSTKLWPV-DCGDEVYNAFQTSCEKLQTDYLDMYMIHMPQL--PDW 113
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
+ + K TW+ +E L VRS+GVSN++ + L +L+ AS+ P
Sbjct: 114 IVNQKETKEK----------TWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHA 163
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
NQVE HP+ +Q LK +C++ I
Sbjct: 164 NQVELHPWFHQADLKNYCDELGI 186
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 118 bits (285), Expect = 9e-26
Identities = 73/190 (38%), Positives = 100/190 (52%)
Frame = +2
Query: 32 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAI 211
+ +P L +G IP +G+GTW E AV+ A+ GYR +D AF Y NE+ VG I
Sbjct: 11 SDIPRLKLPHGHTIPRLGLGTWPMLEDECETAVRFALQSGYRLVDTAFQYRNEEAVGRGI 70
Query: 212 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
+T V R +LFI+SK H D V+ A + SLR L +D+LD+++ HWP
Sbjct: 71 RT----AGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWP------ 120
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
A GK YVD WK L L+ G V+++GVSNF L+ I+D V P
Sbjct: 121 -----VPALGK-------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPD 168
Query: 572 TNQVECHPYL 601
NQ++ P L
Sbjct: 169 VNQIQLSPDL 178
>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
pacificus|Rep: Aldose reductase - Pristionchus pacificus
Length = 293
Score = 118 bits (284), Expect = 1e-25
Identities = 64/193 (33%), Positives = 105/193 (54%), Gaps = 1/193 (0%)
Frame = +2
Query: 68 KIPVIGIGTWKSKPGEV-TQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKR 244
++P+IG+GT++ + V T + +A +GYR ID A +Y NE +G + +++ +KR
Sbjct: 15 RMPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKR 74
Query: 245 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 424
ED+FITSK+ ++ SL +L Y+DL LIHWP + ++
Sbjct: 75 EDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGTSR-----LKSNHKDN 129
Query: 425 IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLN 604
+F YV+ LE L+ G +RS+GVSN+ K L+ +L + P NQ ECHP+
Sbjct: 130 AKFRAETYVE----LETLMDEGKIRSIGVSNYEIKHLETLLAECRILPAINQCECHPHFR 185
Query: 605 QKRLKQFCEDRDI 643
L ++C+++ I
Sbjct: 186 NSELAEYCKEKGI 198
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 118 bits (283), Expect = 2e-25
Identities = 71/204 (34%), Positives = 105/204 (51%), Gaps = 3/204 (1%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGTWKSKPGEVT-QAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKT 217
P L+N ++P++G+GT++ + E T AV A+ GYR D A VY NE +G A++
Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRC 65
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP--QAYKED 391
+ + + RED+FITSKL + R + SL L + Y+DLYLIHWP Q
Sbjct: 66 LLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQGLPVG 124
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
D P + +W+ LE G R++GVSN+ + +Q +L + V P
Sbjct: 125 DKRNPENR-----------AQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPA 173
Query: 572 TNQVECHPYLNQKRLKQFCEDRDI 643
QVE HP L Q L+ C+ R +
Sbjct: 174 VLQVEFHPKLLQNDLRGLCKIRGV 197
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 117 bits (282), Expect = 2e-25
Identities = 68/204 (33%), Positives = 105/204 (51%)
Frame = +2
Query: 32 TSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAI 211
T P LS G ++P++G+GTW K E AV AI+ GYR +D A YGNE+ VG+A+
Sbjct: 6 TPTPTVELSGGTRMPMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVGKAV 65
Query: 212 KTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
+ E R ++F+T+K +H V ALE SL L +DY+DL+L+HWP
Sbjct: 66 R----EAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPMP---- 117
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
+ YVD ++ + L GL +++GVSNF L ++ + P
Sbjct: 118 --------------GEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLI-TEGMTPE 162
Query: 572 TNQVECHPYLNQKRLKQFCEDRDI 643
NQ++ P + ++ F ++ DI
Sbjct: 163 VNQIQLDPSRPRLEVRDFLDNHDI 186
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 117 bits (282), Expect = 2e-25
Identities = 75/195 (38%), Positives = 104/195 (53%), Gaps = 2/195 (1%)
Frame = +2
Query: 65 AKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKR 244
A IPV+G+GTW+S + V + +GY HID A YGNE EVG+ IK Q GV R
Sbjct: 14 ANIPVLGLGTWQSTGQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKGIK---QSGVA-R 69
Query: 245 EDLFITSKLW--NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDAD 418
+ F+T+K++ + P+ + A + SL NL+ DY+DL L+HWP D
Sbjct: 70 DKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP--------------D 115
Query: 419 GKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPY 598
++ S +T AL L GL R++GVSNFN + A V V NQVE HP+
Sbjct: 116 DRVPLS-----ETIPALCELQKQGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVEFHPF 170
Query: 599 LNQKRLKQFCEDRDI 643
+ QK L+ F + I
Sbjct: 171 IKQKTLQTFLNNHHI 185
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 116 bits (280), Expect = 4e-25
Identities = 70/195 (35%), Positives = 103/195 (52%), Gaps = 4/195 (2%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+NGA++P +G G ++ E QAV DAI+ GYR ID A VYGNE E G+ + I
Sbjct: 5 TLNNGAQMPQLGFGVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIAN 64
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
VV RE+LF+T+KLW + + +GA++ SL+ L DY DL L+H P
Sbjct: 65 AVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG---------- 114
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNF---NSKQLQRILDNASVK-PVTN 577
D +KAL G V+S+G+SNF + +++ ++ P +
Sbjct: 115 -----------DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQID 163
Query: 578 QVECHPYLNQKRLKQ 622
Q+E HPY +K +Q
Sbjct: 164 QIEFHPYYQEKVARQ 178
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 116 bits (280), Expect = 4e-25
Identities = 77/198 (38%), Positives = 106/198 (53%), Gaps = 9/198 (4%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGT----WKSKPGEVT-----QAVKDAIDIGYRHIDCAFVYGNEK 193
P +L +G +P++G GT +K P + T + +K A++ G+ HID A YG E+
Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63
Query: 194 EVGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 373
EVG AI+ E + RE LFIT+K+ + V GAL+ SL L +DY+DLYL+H P
Sbjct: 64 EVGIAIR----ESGIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLHNP 116
Query: 374 QAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
+ P D IQ WK LE + G RS+GVSNF L+ IL+
Sbjct: 117 Y-------VIPNLTD--IQ-------SAWKGLEAVKATGKARSIGVSNFQRNHLEAILET 160
Query: 554 ASVKPVTNQVECHPYLNQ 607
SV P NQ+E HPYL +
Sbjct: 161 CSVVPAINQLEYHPYLQR 178
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 116 bits (278), Expect = 6e-25
Identities = 71/198 (35%), Positives = 102/198 (51%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+NG IP +G+GT+ +P + AV A+D Y ID A VY NE+ VG ++ +
Sbjct: 5 TLNNGITIPQVGLGTYLLEPDDAQSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSK- 63
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
R+++F+ +KLW +F A+E +L L DY+DL ++H P
Sbjct: 64 ---ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG---------- 107
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
D V ++ LE G +R++G+SNF+ Q QRILD V P NQVEC
Sbjct: 108 -----------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVEC 156
Query: 590 HPYLNQKRLKQFCEDRDI 643
HPY Q LK +D +I
Sbjct: 157 HPYFPQTELKALLKDHNI 174
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 115 bits (276), Expect = 1e-24
Identities = 71/192 (36%), Positives = 99/192 (51%), Gaps = 1/192 (0%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRED 250
IP G GT++ K + AV++A+D+GYRHID A Y NE EVG+AI + R +
Sbjct: 11 IPTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRGE 66
Query: 251 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 430
LF+T+K+W D +++ SL LN DY+DL L+HWP D K+
Sbjct: 67 LFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP------------SPDNKV- 113
Query: 431 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV-TNQVECHPYLNQ 607
S +Y+ KA + GL R +GVSNF QL L + TNQ+E HP
Sbjct: 114 -SMAEYLKELKACKE---RGLTRHIGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQN 169
Query: 608 KRLKQFCEDRDI 643
K L +C+ +I
Sbjct: 170 KELVAYCQRNNI 181
>UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2;
Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum
lacusprofundi ATCC 49239
Length = 665
Score = 114 bits (275), Expect = 1e-24
Identities = 67/210 (31%), Positives = 98/210 (46%), Gaps = 18/210 (8%)
Frame = +2
Query: 68 KIPVIGIGTWKSKPGEVTQAVKD---AIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVV 238
++P +G G + + GE V A+D GYR +D A +YGNE +GE + G
Sbjct: 375 RLPAVGFGCSRYRDGEYVDRVDSIATALDAGYRLLDSAELYGNEHRIGELLAAP---GAP 431
Query: 239 KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY------------ 382
RE +F+ K W T HR + + A S L ID D Y +HWP A
Sbjct: 432 DRERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSALEHRGELNRLAEK 491
Query: 383 ---KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
+++ FP DG+ +DV W+ LE + G R+LG+ N + QL+ +L+
Sbjct: 492 PVERQETLTFPEGEDGEPATADVALATAWRNLEAVHERGWARTLGICNVSRAQLETVLET 551
Query: 554 ASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
+ P QVE HPY + L + C R I
Sbjct: 552 GEIDPALVQVERHPYRPRNGLVELCHGRGI 581
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 114 bits (274), Expect = 2e-24
Identities = 70/201 (34%), Positives = 109/201 (54%), Gaps = 4/201 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKI-QE 229
L NG++IP G+G + + V+ A+D+GYR ID A Y NE+E GE IK + ++
Sbjct: 12 LLNGSRIPACGVGVYLLPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGIKAWLGKD 71
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNL-NIDYLDLYLIHWPQAYKEDDAIFP 406
KRED+ T+K+ N D +L+ SL + +++Y+DL LIH P + K+
Sbjct: 72 KNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLSDKK------ 125
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD--NASVKPVTNQ 580
++TWKAL+ V G+V+S+GVSNF +Q + D KP+ NQ
Sbjct: 126 ------------TRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQ 173
Query: 581 VECHPYLNQKRLKQFCEDRDI 643
+E P+L +K L +C++ I
Sbjct: 174 IELSPWLMRKDLVDYCQNLGI 194
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 113 bits (273), Expect = 3e-24
Identities = 66/191 (34%), Positives = 105/191 (54%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
TL+NG K+P++G+GT+ +A+ +AI++GYR D A +Y NE E+G AI ++
Sbjct: 5 TLNNGVKMPILGLGTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVKG 64
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G +KRE+ FI +KL + DL + ++E SL+ L +DY+D LIH P Y + A++
Sbjct: 65 G-IKREEFFIQTKLLES-SSEDLAKKSIEKSLKTLGLDYIDSLLIHMP--YSQSKAMY-- 118
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+A+E G++R +G+SNF +K + + V P NQ E
Sbjct: 119 -----------------RAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCET 161
Query: 590 HPYLNQKRLKQ 622
H L QK L++
Sbjct: 162 HLLLQQKPLRE 172
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 113 bits (273), Expect = 3e-24
Identities = 69/186 (37%), Positives = 98/186 (52%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
P TL+NG ++P +G+GTW E +AV AI+ GYR ID A Y NE VG+ I+
Sbjct: 8 PTVTLANGVEMPQLGLGTWPMTDDEAAKAVATAIETGYRLIDTAENYKNETGVGQGIR-- 65
Query: 221 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 400
+ V R+++F+T+K+ +H D R A E SL L +DY+DL+LIHWP
Sbjct: 66 --DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN-------- 115
Query: 401 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQ 580
P YV+ ++ L L+ GLVR++G SNF L + A P NQ
Sbjct: 116 -PDQG---------TYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLF-AAGFVPHVNQ 164
Query: 581 VECHPY 598
++ PY
Sbjct: 165 IQLDPY 170
>UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 253
Score = 113 bits (272), Expect = 3e-24
Identities = 74/208 (35%), Positives = 102/208 (49%), Gaps = 7/208 (3%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
P L++G ++P +G G WK V +AI GYR D A
Sbjct: 4 PTLKLNSGHEMPQVGFGLWKVDNATCADTVYNAIKTGYRLFDGAC--------------- 48
Query: 221 IQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE-DDA 397
DLFI SKLWN+FH D V L + IDY DL+++H+P A + D A
Sbjct: 49 ---------DLFIVSKLWNSFHDGDRVGPITRKQLADWGIDYFDLFIVHFPVALRYVDPA 99
Query: 398 I-FP-----TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 559
+ +P +D +G +Q S +TW+A+E LV GL +S+GVSNF L +L A
Sbjct: 100 VRYPPGWQYSDKEGDVQQSKASIQETWQAMEKLVDEGLAKSIGVSNFQGALLIDLLRYAR 159
Query: 560 VKPVTNQVECHPYLNQKRLKQFCEDRDI 643
++P T Q+E HPYL Q L + E I
Sbjct: 160 IRPATLQIEHHPYLVQNTLLKLAESEGI 187
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 113 bits (271), Expect = 5e-24
Identities = 67/210 (31%), Positives = 102/210 (48%), Gaps = 18/210 (8%)
Frame = +2
Query: 68 KIPVIGIGTWKSKPG---EVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVV 238
++P IG G + + G + ++ A+D GYR +D A +YGNE +G + G
Sbjct: 377 RLPAIGFGCSRYRDGTYIDRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAP---GAP 433
Query: 239 KREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAY------------ 382
R +FI K+W T HR + A SL L ID D Y +HWP+A
Sbjct: 434 DRRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEK 493
Query: 383 ---KEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
+++ FP + G I+ V W+ LE L G R+LG+ N + QL+ +++
Sbjct: 494 SVARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIET 553
Query: 554 ASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
+V+P QVE HPY Q L ++C +R I
Sbjct: 554 GTVRPALVQVERHPYQPQTDLIEYCHERGI 583
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 112 bits (270), Expect = 6e-24
Identities = 70/205 (34%), Positives = 103/205 (50%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M ++P +L++G G+GT+ + E A+ AID GYR +D A Y NE EVG A
Sbjct: 1 MPNIPTISLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGRA 60
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
++ V R++L + SK+ H ++ SL L +D +DL LIHW
Sbjct: 61 VRA----SSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHW------ 110
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
P + G+ ++DTW+ + GLVRS+GVSNF L+ ++D V P
Sbjct: 111 -----PNPSVGR-------WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTP 158
Query: 569 VTNQVECHPYLNQKRLKQFCEDRDI 643
NQVE HPY Q L+ F ++ I
Sbjct: 159 AVNQVELHPYFPQAALRAFHDEHGI 183
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 111 bits (268), Expect = 1e-23
Identities = 69/182 (37%), Positives = 100/182 (54%), Gaps = 1/182 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAID-IGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG +P+IG+G +K++ + AID GYR ID A VY NE+ VG AIK +
Sbjct: 6 LANGLHMPIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAIK----Q 61
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+KRED+FIT+K+W + + + ++ SL+ L +Y+DL L+H P
Sbjct: 62 TKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG---------- 111
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
DY WKALE L G+V+++GVSNF + +L + VKPV NQ+E
Sbjct: 112 -----------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIEL 160
Query: 590 HP 595
HP
Sbjct: 161 HP 162
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 111 bits (267), Expect = 1e-23
Identities = 65/198 (32%), Positives = 104/198 (52%), Gaps = 1/198 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+NG K P G++ + +V A+ GYRHID A +Y NE + G AI ++E
Sbjct: 8 LNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEET 67
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
KRED++ TSKL N +++ S++ + Y+DL+L+H P
Sbjct: 68 GTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG----------- 115
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILD-NASVKPVTNQVEC 589
D +++WKALE V G +R++GVSNF +Q +LD + + P NQ+E
Sbjct: 116 ----------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIEL 165
Query: 590 HPYLNQKRLKQFCEDRDI 643
HP+ +Q+++ +CE + I
Sbjct: 166 HPFCSQQKVVDYCESKGI 183
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 111 bits (266), Expect = 2e-23
Identities = 68/192 (35%), Positives = 104/192 (54%), Gaps = 1/192 (0%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRED 250
+P G+GT++ K V +V++A+ +GYR ID A +Y NE +VG+AI + V R+
Sbjct: 3 VPAFGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRDQ 58
Query: 251 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 430
LF+T+K+W D ++ +L+ SLR L DY+DL LIHWP P D Q
Sbjct: 59 LFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWPS---------PKD-----Q 104
Query: 431 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV-TNQVECHPYLNQ 607
+Y++ AL GL R++GVSNF ++ ++ + TNQ+E HPYL
Sbjct: 105 VPMREYLE---ALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQN 161
Query: 608 KRLKQFCEDRDI 643
+ L F ++ I
Sbjct: 162 RTLIAFLREQGI 173
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 111 bits (266), Expect = 2e-23
Identities = 68/193 (35%), Positives = 100/193 (51%), Gaps = 2/193 (1%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRED 250
+P +G GT+++ + AVK+A+D GY HID A Y NE VG A I++ V RED
Sbjct: 20 VPTLGFGTYRTGGYKCYNAVKNALDCGYTHIDTAMAYENEAAVGRA----IEQSSVDRED 75
Query: 251 LFITSKLWNTFHRPDLVR--GALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 424
+F+T+K+ + R A + L L +YLDL L+HW
Sbjct: 76 IFLTTKIKGYPEMVEYERLIEAAKGCLERLGTEYLDLLLVHWWNPL-------------- 121
Query: 425 IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLN 604
D +T+ AL LV GLV +GVSNF+ K+L++ + + TNQ+E HPY
Sbjct: 122 -----ADMEETFNALNTLVDDGLVGQIGVSNFSIKELKQAMRLSDAPIATNQIEYHPYWG 176
Query: 605 QKRLKQFCEDRDI 643
+ L +FC+D D+
Sbjct: 177 DEELVRFCQDNDV 189
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 110 bits (265), Expect = 2e-23
Identities = 64/196 (32%), Positives = 103/196 (52%)
Frame = +2
Query: 56 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGV 235
+ G ++P +G+GT++ + AV+ A+ +GYRHID A +Y NE +G A+
Sbjct: 6 TQGVRLPKLGLGTFRMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAALAA----AQ 61
Query: 236 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDA 415
+ REDL +T+K+W PD +R A + SL+ L +D++DLYLIHWP A
Sbjct: 62 IAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP-------------A 108
Query: 416 DGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHP 595
G ++ + L L G R++GV+NF L++ +++ NQVE H
Sbjct: 109 TG------MNLPAAMETLMALKQEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVEYHV 162
Query: 596 YLNQKRLKQFCEDRDI 643
L+Q +L + + R I
Sbjct: 163 MLDQSKLMAYMKSRSI 178
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 109 bits (262), Expect = 6e-23
Identities = 77/209 (36%), Positives = 108/209 (51%), Gaps = 4/209 (1%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKI---PVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEV 199
MT TT SN A + P++G GT++ K AV A++ G RHID A +YGNE+ V
Sbjct: 1 MTQTNATT-SNQAPLTAMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAV 59
Query: 200 GEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQA 379
G+AI T + RE+LFIT+K+W + ++ SL L YLDL LIHWP
Sbjct: 60 GDAINTS----GIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLN 115
Query: 380 YKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS 559
E S V+Y+ KA+ + GL R +GVSNF + QL + +
Sbjct: 116 SDEP--------------SMVEYLSELKAV---LDKGLTRRIGVSNFTNAQLAQAIAILG 158
Query: 560 VKPV-TNQVECHPYLNQKRLKQFCEDRDI 643
+ TNQVE HPYL +++ FC ++
Sbjct: 159 EGVIYTNQVEVHPYLINRKVTDFCRQHNV 187
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 109 bits (261), Expect = 7e-23
Identities = 70/195 (35%), Positives = 103/195 (52%), Gaps = 1/195 (0%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE 205
MT +P L++G +IP +G G ++ S E +AV+ AI GYR ID A Y N+ VGE
Sbjct: 1 MTDIPKIKLNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGE 60
Query: 206 AIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYK 385
AIK V R+D+F+T+KLW + + A++ L+ L DY+D+ L+H QAY
Sbjct: 61 AIKNSD----VNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH--QAYG 114
Query: 386 EDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVK 565
D W+ALE G +S+GVSNF QL + ++VK
Sbjct: 115 -------------------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVK 155
Query: 566 PVTNQVECHPYLNQK 610
PV NQ+E +P+ ++
Sbjct: 156 PVVNQIEVNPWFQRE 170
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 109 bits (261), Expect = 7e-23
Identities = 75/213 (35%), Positives = 101/213 (47%), Gaps = 8/213 (3%)
Frame = +2
Query: 29 MTSVPVT-TLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGE 205
MT+ T TL+ IP +G GT+ + + AI GYRHID A Y NEK VG
Sbjct: 33 MTNTATTFTLNTTTTIPAVGFGTYLISNDDAKSTISAAIQAGYRHIDTASGYQNEKTVGA 92
Query: 206 AIKTKIQEGVVKREDLFITSKLW--NTF--HRPDLVRGAL---EVSLRNLNIDYLDLYLI 364
IK +Q + R+DLF+T+KLW N P L + SL L +DY+DLYLI
Sbjct: 93 GIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVDLYLI 152
Query: 365 HWPQAYKEDDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRI 544
H P G ++ ++ W+AL L +G RS+GVSNFN L I
Sbjct: 153 HAPYG-------------GDMR------LEQWRALLELQANGKARSIGVSNFNESHLNEI 193
Query: 545 LDNASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
P NQ+E HP+ + L + + I
Sbjct: 194 KAAGLPMPDANQIELHPWSQKPDLLAYMDQHAI 226
>UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3;
Magnoliophyta|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 304
Score = 109 bits (261), Expect = 7e-23
Identities = 49/76 (64%), Positives = 60/76 (78%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+ GAK+P +G+GTW+S PG V QAV AI +GYRHIDCA VYGNE+E+G +K +G
Sbjct: 10 LNTGAKMPSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGIVLKKLFDDG 69
Query: 233 VVKREDLFITSKLWNT 280
VVKREDL+ITSKLW T
Sbjct: 70 VVKREDLWITSKLWCT 85
Score = 33.5 bits (73), Expect = 4.5
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = +2
Query: 554 ASVKPVTNQVECHPYLNQKRLKQFCEDRDI 643
A V P QVECHP Q +L FC+ + +
Sbjct: 153 ARVPPAVIQVECHPSWQQSKLHAFCKSKGV 182
>UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2;
Trypanosoma|Rep: Aldo/keto reductase, putative -
Trypanosoma cruzi
Length = 322
Score = 109 bits (261), Expect = 7e-23
Identities = 72/215 (33%), Positives = 108/215 (50%), Gaps = 12/215 (5%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
++P+ S G +IP +G+GT++ E AV A+ +G+R +D A Y NE+ VG A
Sbjct: 14 ALPLLESSGGMRIPHMGVGTYELYGDESRIAVLAALRLGFRLVDTAAGYHNEEHVGAA-- 71
Query: 215 TKIQEGVVKREDLFITSKLW-NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
I+E V+RE+LF+ K+ +LV + S+R L I Y D LIHWP
Sbjct: 72 --IEESGVQREELFVVVKIAPKAMASEELVEKGIRESVRKLRIAYADCVLIHWPGC---- 125
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNAS---- 559
+ P +A+G WK ++ L G++R LGVSNF + ++ NA+
Sbjct: 126 GGLKPEEAEGHRAARH----RCWKVMQALKKEGIIRHLGVSNFAPRHFPHLVGNAAEEAH 181
Query: 560 -------VKPVTNQVECHPYLNQKRLKQFCEDRDI 643
+PV NQ+E HP Q+ FC +RDI
Sbjct: 182 LFDAANPCRPVINQIELHPLCVQQEACDFCRERDI 216
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 108 bits (259), Expect = 1e-22
Identities = 63/191 (32%), Positives = 102/191 (53%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L+NG ++P+IGIG W P + ++V +A+ GYR ID A +Y NE+ VG A++ +
Sbjct: 47 LNNGIEMPIIGIGVWTLTPEQTEKSVGEALKAGYRLIDTARMYRNEQAVGRAVR----DS 102
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
+ RE++FIT+K++ + + A+ LR L+ DY+DL L+H+P
Sbjct: 103 GIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDYIDLLLLHYP------------- 148
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
D + WK +E V G +R++G+SN++ K RI+ A++ P Q E H
Sbjct: 149 --------DQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVH 200
Query: 593 PYLNQKRLKQF 625
Y K+ K F
Sbjct: 201 IYNQDKQTKAF 211
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 107 bits (258), Expect = 2e-22
Identities = 68/177 (38%), Positives = 93/177 (52%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRED 250
IP +G+GTW + T+AV I+ GYR ID A +Y NE VG A+ E V RE+
Sbjct: 4 IPPLGLGTWPLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREE 59
Query: 251 LFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQ 430
LF+T+KL + H +RGA+E SL+NL +D LDL+LIHWP
Sbjct: 60 LFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPLPRHN-------------- 105
Query: 431 FSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYL 601
YV ++A+ GLVR +GVSNF L+R++ P NQ++ P L
Sbjct: 106 ----RYVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSL 158
>UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 212
Score = 107 bits (257), Expect = 2e-22
Identities = 67/183 (36%), Positives = 101/183 (55%), Gaps = 4/183 (2%)
Frame = +2
Query: 44 VTTLSNGAKIPVIGIGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
+T S G IP++G+ T + P E + ++ AI++GYRH DC Y +EK +GEAIK
Sbjct: 1 MTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKPLGEAIK 60
Query: 215 TKIQEGVVK-REDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
++ G++K R++LFIT + AL NL +DYLDLYLIHW + K
Sbjct: 61 KAVKLGLIKSRDELFITLQ-------------AL-----NLQLDYLDLYLIHWSVSLKPG 102
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
+ P + D + +D WKA+E L +++GVSNF+ +L+ +L AS+ P
Sbjct: 103 NYELPVNKDDHLP---IDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPA 159
Query: 572 TNQ 580
NQ
Sbjct: 160 VNQ 162
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 107 bits (257), Expect = 2e-22
Identities = 67/197 (34%), Positives = 98/197 (49%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
+ +G IP G+G ++ E VK A++ GYRH+D A Y NE G+AI ++
Sbjct: 35 MHDGNAIPQFGLGVYEMNDKETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKAT 94
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
RE++F+TSKL N L+ SL+ ++Y DLYL+H AI
Sbjct: 95 GTSREEIFLTSKLKNNSSYEQAFVD-LKGSLKRSGVEYFDLYLMH--------SAI---- 141
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
G + +V WKAL GLV+S+GVSNF K +Q +D P NQV+ H
Sbjct: 142 -GGPVIRKNV-----WKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLH 195
Query: 593 PYLNQKRLKQFCEDRDI 643
P++ + + CE +I
Sbjct: 196 PFMRHPEIVEICEQNEI 212
>UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1;
Filobasidiella neoformans|Rep: Oxidoreductase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 321
Score = 107 bits (256), Expect = 3e-22
Identities = 76/204 (37%), Positives = 110/204 (53%), Gaps = 6/204 (2%)
Frame = +2
Query: 50 TLSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIDCA---FVYGNEKEVGEAIKT 217
TL++G +IP I GTWK P EVT V AID+G+ HID A VY NE+EVG+AIK
Sbjct: 7 TLNDGHRIPAIAFGTWKI-PKEVTPFQVGQAIDVGFDHIDTAQGRIVYHNEEEVGQAIK- 64
Query: 218 KIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDA 397
E + R L++T+K W+ R ++ SL L ++YLDLYLIH PQ K D
Sbjct: 65 ---ESGLSRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQVTKGDIK 119
Query: 398 IFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTN 577
+ + + + K + S +FN +QLQ +L +A+VKPV N
Sbjct: 120 GAWKELETLQKEGKTKSIGVSKQVYYQTIFFASLSDVWDSFNKEQLQELLAHATVKPVVN 179
Query: 578 QVECHPYLNQKR--LKQFCEDRDI 643
Q+ HPY+ + L ++ E+++I
Sbjct: 180 QILLHPYVITRTAPLLEYLEEQNI 203
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 106 bits (255), Expect = 4e-22
Identities = 72/192 (37%), Positives = 104/192 (54%), Gaps = 1/192 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L++G IP G+G ++ GE T+ AVK+A+ +GYRHID A Y NE+ VG AI +
Sbjct: 7 LNDGNIIPQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHS---S 63
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
G+ E ++ITSKLW + + D A+E L LN+ +DL L+H
Sbjct: 64 GIPISE-IWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLHQQVG---------- 110
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
+Y W ALE V G V+S+G+SNF+ ++L + + A +KP QVE
Sbjct: 111 -----------NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVET 159
Query: 590 HPYLNQKRLKQF 625
HPY QK L++F
Sbjct: 160 HPYHQQKELQEF 171
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 106 bits (254), Expect = 5e-22
Identities = 70/196 (35%), Positives = 104/196 (53%), Gaps = 3/196 (1%)
Frame = +2
Query: 65 AKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKR 244
A IP +G GTW E Q V A++ G RHID A YGNE++V IK + V R
Sbjct: 8 AGIPQMGYGTWNRSADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIK----DAGVAR 63
Query: 245 EDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGK 424
++FIT+K+ + P V ++ SL L +D +DL L+HWP + + +P AD
Sbjct: 64 NEIFITTKVKPDNYGPGAVMPSVRESLEKLRVDQVDLLLLHWPSPHNK----YPL-ADYL 118
Query: 425 IQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQ---RILDNASVKPVTNQVECHP 595
QF++V D+ GL R +GVSNF + R+LD+ ++ TNQVECH
Sbjct: 119 GQFAEV--FDS----------GLARQIGVSNFTKAMIDESIRLLDSRTI--TTNQVECHV 164
Query: 596 YLNQKRLKQFCEDRDI 643
Y+ + + +C++ I
Sbjct: 165 YMQNRPIIDYCQNLGI 180
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 106 bits (254), Expect = 5e-22
Identities = 66/198 (33%), Positives = 101/198 (51%), Gaps = 5/198 (2%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE- 229
LSNG IP I +G + E T+AV+ A+ GYR D A Y NE+E G+AI + +
Sbjct: 15 LSNGLSIPQIQLGLYMMSGPETTRAVRWALGAGYRGFDSAQWYYNEREAGQAILSFLSSP 74
Query: 230 ---GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAI 400
+ R+D+ TSKL + D VR ++ S++ + Y+DL+L+H P +E
Sbjct: 75 ENTAGLTRKDVHFTSKLRDNSTNYDAVRASISKSVKASGLGYIDLFLLHSPLGGRE---- 130
Query: 401 FPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNA-SVKPVTN 577
+ +WKA+E V G V+ GVSN+ K L ++ +KP+ N
Sbjct: 131 --------------ARLTSWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPLVN 176
Query: 578 QVECHPYLNQKRLKQFCE 631
Q+ECHP+ Q ++ CE
Sbjct: 177 QIECHPFNTQPEIRAACE 194
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 106 bits (254), Expect = 5e-22
Identities = 66/188 (35%), Positives = 95/188 (50%)
Frame = +2
Query: 77 VIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKREDLF 256
++G+GTW V ++V+ +++GY H+D A Y NE E+GEA+ RED+F
Sbjct: 1 MVGVGTWDIDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD------YDREDVF 54
Query: 257 ITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKIQFS 436
+TSK+ + V A E SL L DYLDLYL+HWP P
Sbjct: 55 LTSKVLPKHLDYESVIEACEASLDRLGTDYLDLYLVHWPN---------PA--------- 96
Query: 437 DVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQKRL 616
+T A+ L G +R++GVSNF++ QL A V NQ+E HP+ Q ++
Sbjct: 97 -TSIRETMNAMATLHDQGKIRNVGVSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQV 155
Query: 617 KQFCEDRD 640
+FC D D
Sbjct: 156 VEFCRDTD 163
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 105 bits (253), Expect = 7e-22
Identities = 66/188 (35%), Positives = 100/188 (53%), Gaps = 1/188 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG ++P++G GT++ + GE QAVK+AI GYRHID A Y NE+ VG I
Sbjct: 6 LNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGIAA---- 61
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V R++LFIT+K+W V + + SL+ L +DY+DL LIH P
Sbjct: 62 SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP------------ 109
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
++DV W A+E L G ++++GVSNF ++ + + P NQ+E
Sbjct: 110 -------YNDV--YGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEI 160
Query: 590 HPYLNQKR 613
+P+ Q +
Sbjct: 161 NPFQQQSK 168
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 105 bits (253), Expect = 7e-22
Identities = 67/203 (33%), Positives = 103/203 (50%), Gaps = 1/203 (0%)
Frame = +2
Query: 35 SVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
++P TL +G +P +G+GT+ ++ +V+ A+ GY HID A Y NE+ +GE +
Sbjct: 33 TIPTQTLPSGDTLPALGLGTYALDDDQIADSVRAALSSGYTHIDTAEGYHNEEAIGEVL- 91
Query: 215 TKIQEGVVKREDLFITSK-LWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKED 391
R+D+F+TSK L L++ + E SL L DYLDLYLIHWP
Sbjct: 92 -----AEYDRDDVFLTSKVLAKNLGYESLIQ-SCEASLERLETDYLDLYLIHWPN----- 140
Query: 392 DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPV 571
P + ++ +A+ L GLVR++GVSNF++ QL + V
Sbjct: 141 ----PA----------ISLRESLQAMAELHDRGLVRNVGVSNFSAYQLSCANHISEVPIA 186
Query: 572 TNQVECHPYLNQKRLKQFCEDRD 640
NQ+E HP+ + L +C + D
Sbjct: 187 VNQIEFHPWFQRPNLVDYCHESD 209
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 105 bits (252), Expect = 9e-22
Identities = 64/197 (32%), Positives = 98/197 (49%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
L++G +P G G W +V ++ A+ G+RH D A Y NE VG A++
Sbjct: 8 LNDGYYMPRPGCGLWLIDNRDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRALRYT---- 63
Query: 233 VVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTD 412
V RE LFITSK+ + +L L ++YL+L+LIHWP K
Sbjct: 64 EVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAKN-------- 115
Query: 413 ADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECH 592
YV+TW+A L GL+RS+GVSNF + ++R++++ V P NQ+E H
Sbjct: 116 ----------LYVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELH 165
Query: 593 PYLNQKRLKQFCEDRDI 643
P+ Q ++ + + I
Sbjct: 166 PHFQQCDVRDYHHEAGI 182
>UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2;
Ostreococcus|Rep: Aldo/keto reductase family proteins -
Ostreococcus tauri
Length = 336
Score = 105 bits (252), Expect = 9e-22
Identities = 66/206 (32%), Positives = 105/206 (50%), Gaps = 1/206 (0%)
Frame = +2
Query: 17 SNLIMTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKE 196
+ ++ T+ ++ G +P++ GT++ + AV+DA+ G++H+D A VYGNE++
Sbjct: 44 TRVMSTTKWTRAIAPGITMPMLAFGTYRLRGETCRDAVRDALRCGFQHVDTASVYGNERD 103
Query: 197 VGEAIKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQ 376
VGEA++ +E E +F+TSK+ + R + A + DL L+HWP
Sbjct: 104 VGEALRACHRE---VSERIFVTSKIAPSEMRSEEEAAAAIAGVNERLGRTPDLVLVHWPG 160
Query: 377 AYKED-DAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDN 553
KE D+ DA TW+ALE + G R++GVSN+ L+ +L
Sbjct: 161 RDKESPDSERHRDARRW----------TWRALENALKMGQCRAIGVSNYELSHLRELLQF 210
Query: 554 ASVKPVTNQVECHPYLNQKRLKQFCE 631
VKP NQ+E H Q L+ FCE
Sbjct: 211 CDVKPAVNQIELHARFPQTELRAFCE 236
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 104 bits (250), Expect = 2e-21
Identities = 68/186 (36%), Positives = 98/186 (52%), Gaps = 1/186 (0%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWK-SKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQE 229
L+NG ++P++G GT++ + E AVKDAI GYRHID A Y NE+ VG I
Sbjct: 6 LNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAA---- 61
Query: 230 GVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
V R++LFIT+K+W V + + SL+ L +DY+DL LIH P
Sbjct: 62 SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP------------ 109
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
F+DV W A+E L G +R++GVSNF+ ++ + V P NQ+E
Sbjct: 110 -------FNDV--YGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEV 160
Query: 590 HPYLNQ 607
+P+ Q
Sbjct: 161 NPFQQQ 166
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 104 bits (250), Expect = 2e-21
Identities = 68/198 (34%), Positives = 106/198 (53%), Gaps = 2/198 (1%)
Frame = +2
Query: 56 SNGAKIPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
S+G ++P IG+G + + + + +++ A+ GYR D A +Y NE +G ++K + +
Sbjct: 15 SDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKYLPQF 74
Query: 233 VVKREDLFITSKLWNTFHRP-DLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPT 409
+ RED+FIT+K+ + L SL L DY+DL LIH+P+ D
Sbjct: 75 GLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPR-----DRDTGN 129
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVEC 589
D D +I S V W+ LE G VRS+GVSN+ L + + A ++PV NQ E
Sbjct: 130 DDDYEINKSRRKIV--WQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYEY 187
Query: 590 HPYLNQKRLKQFCEDRDI 643
PYL + LK+FC+ +I
Sbjct: 188 QPYLTRPTLKKFCDLNNI 205
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 104 bits (250), Expect = 2e-21
Identities = 65/201 (32%), Positives = 106/201 (52%), Gaps = 4/201 (1%)
Frame = +2
Query: 53 LSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEG 232
LS+G +IP +G+G ++ V V +A+++GYR D A Y NE V I ++
Sbjct: 15 LSDGTQIPSVGLGVYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGVARGIAAWLKHA 74
Query: 233 V-VKREDLFITSKLWNTFHRPDLVRGALEVSLRNLN-IDYLDLYLIHWPQAYKEDDAIFP 406
+RED++ T+K+ H + + +LE SL + Y+DL L+H P
Sbjct: 75 PGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAPM---------- 124
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRIL--DNASVKPVTNQ 580
+D ++ TW+ALE V G VRS+GVSN+ + L +L + ++PV NQ
Sbjct: 125 SDRTRRL--------GTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQ 176
Query: 581 VECHPYLNQKRLKQFCEDRDI 643
VE +P+L ++ L Q+C + +I
Sbjct: 177 VEINPWLCRQELVQYCRENNI 197
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 104 bits (249), Expect = 2e-21
Identities = 61/191 (31%), Positives = 96/191 (50%), Gaps = 1/191 (0%)
Frame = +2
Query: 71 IPVIGIGTWKSKPGE-VTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGVVKRE 247
+P++G+GTW+++ E ++V+ A++ GYRHID A Y NE VG+ I V R+
Sbjct: 17 MPMLGLGTWQNEDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAA----ADVDRD 72
Query: 248 DLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFPTDADGKI 427
D+F+ +K+W + D V E SL L +D +DL +HW E + P
Sbjct: 73 DIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP------- 125
Query: 428 QFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVECHPYLNQ 607
A + LV GL+ ++GVSNF ++ +D NQVE HP+L Q
Sbjct: 126 ------------AFDELVDRGLIDNVGVSNFEPHHVETAMDVLDAPVFANQVETHPFLQQ 173
Query: 608 KRLKQFCEDRD 640
L++ ++D
Sbjct: 174 SELREHAAEQD 184
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 103 bits (248), Expect = 3e-21
Identities = 64/196 (32%), Positives = 101/196 (51%)
Frame = +2
Query: 47 TTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQ 226
T ++GA IP +G G ++ EV + + A++ G+RH D A +Y NE +G A ++
Sbjct: 3 TVTAHGATIPALGFGVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRA----LE 58
Query: 227 EGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDDAIFP 406
+REDLF+T+K+W + D +++ SL L +D +DL L+HWP A++ P
Sbjct: 59 RAGARREDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP-AHE-----VP 112
Query: 407 TDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVTNQVE 586
A ++ A++ G R +GVSN N Q++ + ++ VTNQVE
Sbjct: 113 VAAQ----------IERLNAVKDA---GKTRFIGVSNQNIAQMRESIARSAAPIVTNQVE 159
Query: 587 CHPYLNQKRLKQFCED 634
HPYL Q L D
Sbjct: 160 LHPYLPQHSLVAAARD 175
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 103 bits (248), Expect = 3e-21
Identities = 53/115 (46%), Positives = 70/115 (60%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
MTSVP TL+NG ++P +G G ++ E AV A++ GYR ID A YGNE VG A
Sbjct: 1 MTSVPTVTLNNGVEMPQLGYGVFQVPEDETAAAVGAALEAGYRSIDTAAAYGNEAAVGRA 60
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWP 373
+ G+ R++LF+T+KLWN D A + SL L +D+LDLYLIHWP
Sbjct: 61 L---AGSGLA-RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 103 bits (248), Expect = 3e-21
Identities = 66/199 (33%), Positives = 106/199 (53%), Gaps = 3/199 (1%)
Frame = +2
Query: 56 SNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTKIQEGV 235
++ KIP +G G ++S G+ Q+ A++ GYRHID A YGNEKEVGEA++ +
Sbjct: 15 NSDVKIPRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEALR----KCG 70
Query: 236 VKREDLFITSKLWNTFHRPDLVRGALEVSLRNL--NIDYLDLYLIHWPQAYKEDDAIFPT 409
+ R D+F+T+K+ + P+ L S+ + Y+DL+LIH +
Sbjct: 71 IPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH-------------S 117
Query: 410 DADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASV-KPVTNQVE 586
+ G ++ W+ALE L+ G RS+GVSNF K ++ + A V P NQ+E
Sbjct: 118 SSSGSAGRKEL-----WQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIE 172
Query: 587 CHPYLNQKRLKQFCEDRDI 643
HP+ Q+ ++ +C+ I
Sbjct: 173 LHPWCQQRVIEAYCKRNGI 191
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 103 bits (246), Expect = 5e-21
Identities = 69/205 (33%), Positives = 98/205 (47%)
Frame = +2
Query: 29 MTSVPVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEA 208
M V L++G +P IG G ++ P + V D+GYR +D A Y NE+ VGE
Sbjct: 1 MVPVKNVVLNDGHSMPAIGQGVYQLNPAQAESMVALGYDLGYRAVDTAAWYENEEGVGEG 60
Query: 209 IKTKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKE 388
++++ FIT+KL AL+ S+RNL + L+LYLIHWP
Sbjct: 61 LRSRHARS-------FITTKLMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP----- 108
Query: 389 DDAIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKP 568
D K Y +TW+ L + G S+GVSNF L I+ ++ V P
Sbjct: 109 -------GQDRK------RYEETWQTLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVP 155
Query: 569 VTNQVECHPYLNQKRLKQFCEDRDI 643
NQ+E HPY QK L+ + +R I
Sbjct: 156 AVNQIELHPYFQQKELRAYHAERGI 180
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 102 bits (244), Expect = 9e-21
Identities = 67/203 (33%), Positives = 108/203 (53%), Gaps = 2/203 (0%)
Frame = +2
Query: 41 PVTTLSNGAKIPVIGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIKTK 220
P+ TL++G +IP+IG+GT A+K A++IG R D A +YGNEKEVGE I+
Sbjct: 35 PLLTLNDGYQIPIIGLGTTSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEVGETIR-- 92
Query: 221 IQEGVVKREDLFITSKLW--NTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
E + R ++F+ +KL+ F P+ A+E +L LN DY+D+ L+H P E+D
Sbjct: 93 --ESNINRNEIFVITKLYPGAQFANPE---KAIEEALNKLNTDYIDMMLLHHP---GEND 144
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
V +KA+E + G ++S+G+SN+ K++ L ++KP
Sbjct: 145 ------------------VKAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKPSL 186
Query: 575 NQVECHPYLNQKRLKQFCEDRDI 643
Q E H Y +K + + + +I
Sbjct: 187 IQNEIHIYYQEKEVVPYMHNLNI 209
>UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 289
Score = 100 bits (239), Expect = 3e-20
Identities = 69/191 (36%), Positives = 103/191 (53%), Gaps = 1/191 (0%)
Frame = +2
Query: 38 VPVTTLSNGAKIPV-IGIGTWKSKPGEVTQAVKDAIDIGYRHIDCAFVYGNEKEVGEAIK 214
+P+ L +G +IP+ +G T+ ++T+AV I+ G+ H+DCA +YG E+EV AIK
Sbjct: 3 IPLLRLRDGNQIPLDLGDTTFGQGLVDLTKAV---IEKGFYHLDCAEMYGTEEEVAIAIK 59
Query: 215 TKIQEGVVKREDLFITSKLWNTFHRPDLVRGALEVSLRNLNIDYLDLYLIHWPQAYKEDD 394
E V RE LFIT+K+ D + A++ SL+ + +Y DLYLIH P K
Sbjct: 60 ----ESGVPREKLFITNKVAQGI---DDIEAAIDQSLQKMQTNYFDLYLIHIPFFAK--- 109
Query: 395 AIFPTDADGKIQFSDVDYVDTWKALEPLVCHGLVRSLGVSNFNSKQLQRILDNASVKPVT 574
S+ D+ WK +E + G RS+GVSN+ ++ L A+ PVT
Sbjct: 110 -------------SEEDFQRAWKTMEGIQKAGKARSIGVSNYMRPHIEATLKGATSPPVT 156
Query: 575 NQVECHPYLNQ 607
NQ+E H YL +
Sbjct: 157 NQIEYHAYLQR 167
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 616,017,073
Number of Sequences: 1657284
Number of extensions: 12756614
Number of successful extensions: 46063
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 43313
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 45438
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48541014171
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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