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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000012-TA|BGIBMGA000012-PA|IPR012464|Protein of unknown
function DUF1676, IPR000005|Helix-turn-helix, AraC type
         (497 letters)

Database: fruitfly 
           52,641 sequences; 24,830,863 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AE014297-421|AAF51900.1|  233|Drosophila melanogaster CG15592-PA...    81   3e-15
AY070617-1|AAL48088.1|  233|Drosophila melanogaster RE71995p pro...    80   8e-15
BT016007-1|AAV36892.1|  288|Drosophila melanogaster RE26656p pro...    60   9e-09
AE014297-419|AAF51902.1|  288|Drosophila melanogaster CG1153-PA ...    60   9e-09
BT009951-1|AAQ22420.1|  295|Drosophila melanogaster RH51767p pro...    47   7e-05
AE014297-425|AAF51897.2|  295|Drosophila melanogaster CG1154-PA ...    47   7e-05
AE014297-420|AAF51901.1|  274|Drosophila melanogaster CG15591-PA...    43   0.001
AE014297-432|AAN13237.1|  278|Drosophila melanogaster CG31561-PA...    42   0.001
AF132170-1|AAD34758.1|  286|Drosophila melanogaster unknown prot...    40   0.010
AE014297-418|AAF51903.2|  312|Drosophila melanogaster CG1151-PA ...    40   0.010
AE014134-2062|AAF53094.1|  282|Drosophila melanogaster CG14925-P...    31   4.8  
AE014297-4594|AAF57047.2|  250|Drosophila melanogaster CG15538-P...    30   6.4  
AE014296-852|AAF47904.2|  242|Drosophila melanogaster CG11345-PA...    30   6.4  
AY119041-1|AAM50901.1|  393|Drosophila melanogaster LP06455p pro...    30   8.4  
AE014297-416|AAF51905.3|  393|Drosophila melanogaster CG10303-PA...    30   8.4  

>AE014297-421|AAF51900.1|  233|Drosophila melanogaster CG15592-PA
           protein.
          Length = 233

 Score = 81.4 bits (192), Expect = 3e-15
 Identities = 62/244 (25%), Positives = 110/244 (45%), Gaps = 17/244 (6%)

Query: 1   MLKYIALLALTASVQCNPLKENSISENLVGVISECIERDTSLCIKEKALKFTERLAFSKD 60
           M K++ L AL AS      + +S+  + + ++ +C ER   LC+KE+AL + +  A + D
Sbjct: 1   MFKFVCLFALIASTAAATSEADSLLTSALKMVKDCGERSMVLCMKERALHYFD--AENGD 58

Query: 61  MNIFDGMSLVNIGSARSARSYE--PLAEDPKARELQLDERIADNMGDFLENHVIQLRLSE 118
           + + +G++LV        RS     L E+ +ARE ++D  + + +  F   H +Q ++ +
Sbjct: 59  VRLTEGIALVKTDEIPVGRSLNEMQLPEEVEAREAEVDSLLVERVARFFGTHTLQFKVPK 118

Query: 119 PEAE--SRSLDDEARGXXXXXXXXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKI 176
              +   R+L +E+RG                            G +A ++ KA+ +GKI
Sbjct: 119 DSIQDMQRAL-EESRGKKKEKKKYLMPLLMLFKLKMAALLPLAIGFLALISFKALVIGKI 177

Query: 177 AFAMSAFQLIRKLLNKNQXXXXXXXXYAAPHHHEEHPGYSYEPASSGGWGRQATDAQSLA 236
           A  +S    ++KLL   +         A PH+  EH      P+         + AQ LA
Sbjct: 178 ALLLSGIIGLKKLLESKK---ENYEVVAHPHYEHEHSYGRSLPSDD-------SQAQQLA 227

Query: 237 YAVH 240
           YA +
Sbjct: 228 YAAY 231


>AY070617-1|AAL48088.1|  233|Drosophila melanogaster RE71995p
           protein.
          Length = 233

 Score = 79.8 bits (188), Expect = 8e-15
 Identities = 61/244 (25%), Positives = 110/244 (45%), Gaps = 17/244 (6%)

Query: 1   MLKYIALLALTASVQCNPLKENSISENLVGVISECIERDTSLCIKEKALKFTERLAFSKD 60
           M +++ L AL AS      + +S+  + + ++ +C ER   LC+KE+AL + +  A + D
Sbjct: 1   MFEFVCLFALIASTAAATSEADSLLTSALKMVKDCGERSMVLCMKERALHYFD--AENGD 58

Query: 61  MNIFDGMSLVNIGSARSARSYE--PLAEDPKARELQLDERIADNMGDFLENHVIQLRLSE 118
           + + +G++LV        RS     L E+ +ARE ++D  + + +  F   H +Q ++ +
Sbjct: 59  VRLTEGIALVKTDEIPVGRSLNEMQLPEEVEAREAEVDSLLVERVARFFGTHTLQFKVPK 118

Query: 119 PEAE--SRSLDDEARGXXXXXXXXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKI 176
              +   R+L +E+RG                            G +A ++ KA+ +GKI
Sbjct: 119 DSIQDMQRAL-EESRGKKKEKKKYLMPLLMLFKLKMAALLPLAIGFLALISFKALVIGKI 177

Query: 177 AFAMSAFQLIRKLLNKNQXXXXXXXXYAAPHHHEEHPGYSYEPASSGGWGRQATDAQSLA 236
           A  +S    ++KLL   +         A PH+  EH      P+         + AQ LA
Sbjct: 178 ALLLSGIIGLKKLLESKK---ENYEVVAHPHYEHEHSYGRSLPSDD-------SQAQQLA 227

Query: 237 YAVH 240
           YA +
Sbjct: 228 YAAY 231


>BT016007-1|AAV36892.1|  288|Drosophila melanogaster RE26656p
           protein.
          Length = 288

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 69/278 (24%), Positives = 115/278 (41%), Gaps = 53/278 (19%)

Query: 5   IALLALTASVQCNPLK---ENSIS-ENLV--GVISECIERDTSLCIKEKALKFTERLAFS 58
           + L+AL+A++     +    N+I  EN +   + S+C+ +D+  C+K K   F +++  +
Sbjct: 11  LCLVALSAALPAEETRGHARNAIGGENDIMDSIYSDCLRKDSVSCVKYKLFSFVDKVLGA 70

Query: 59  KDM-NIFDGMSLVNIGSARSARSYEPLAEDPKARELQLDERIADNMGDFLENHVIQLRLS 117
           +D   + +G+++V    A    +   ++ D     L L+      +  FL +H I++ L 
Sbjct: 71  RDQFALTEGVTVVRSPDAPQQEAARSISGDESFESLALNR-----ISSFLNSHTIKVELK 125

Query: 118 EPE------AESRSLDD---------------EARGXXXXXXXXXXXXXXXXXXXXXXXX 156
             +      +  R+L+D               E+RG                        
Sbjct: 126 GADIVQAVSSTGRALEDASESLFGSNDPNAPEESRGKKKKAAKILGPILALVALKAAALL 185

Query: 157 XXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLNKNQXXXXXXXXYAAPHHHEEH---- 212
               G IA +A KA+ +GKIA  +SA   ++KLL  +Q         A PHH   H    
Sbjct: 186 PLLLGAIALIAGKALLIGKIALVLSAVIGLKKLL--SQEKHVTYEVVAHPHHSSSHSTSH 243

Query: 213 ----PGY---------SYEPASSGGWGRQATDAQSLAY 237
                GY         SY  +  GGWGR + DAQ LAY
Sbjct: 244 DSYGSGYSADAGASSASYGSSGHGGWGR-SIDAQDLAY 280


>AE014297-419|AAF51902.1|  288|Drosophila melanogaster CG1153-PA
           protein.
          Length = 288

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 69/278 (24%), Positives = 115/278 (41%), Gaps = 53/278 (19%)

Query: 5   IALLALTASVQCNPLK---ENSIS-ENLV--GVISECIERDTSLCIKEKALKFTERLAFS 58
           + L+AL+A++     +    N+I  EN +   + S+C+ +D+  C+K K   F +++  +
Sbjct: 11  LCLVALSAALPAEETRGHARNAIGGENDIMDSIYSDCLRKDSVSCVKYKLFSFVDKVLGA 70

Query: 59  KDM-NIFDGMSLVNIGSARSARSYEPLAEDPKARELQLDERIADNMGDFLENHVIQLRLS 117
           +D   + +G+++V    A    +   ++ D     L L+      +  FL +H I++ L 
Sbjct: 71  RDQFALTEGVTVVRSPDAPQQEAARSISGDESFESLALNR-----ISSFLNSHTIKVELK 125

Query: 118 EPE------AESRSLDD---------------EARGXXXXXXXXXXXXXXXXXXXXXXXX 156
             +      +  R+L+D               E+RG                        
Sbjct: 126 GADIVQAVSSTGRALEDASESLFGSNDPNAPEESRGKKKKAAKILGPILALVALKAAALL 185

Query: 157 XXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLNKNQXXXXXXXXYAAPHHHEEH---- 212
               G IA +A KA+ +GKIA  +SA   ++KLL  +Q         A PHH   H    
Sbjct: 186 PLLLGAIALIAGKALLIGKIALVLSAVIGLKKLL--SQEKHVTYEVVAHPHHSSSHSTSH 243

Query: 213 ----PGY---------SYEPASSGGWGRQATDAQSLAY 237
                GY         SY  +  GGWGR + DAQ LAY
Sbjct: 244 DSYGSGYSADAGASSASYGSSGHGGWGR-SIDAQDLAY 280


>BT009951-1|AAQ22420.1|  295|Drosophila melanogaster RH51767p
           protein.
          Length = 295

 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 51/226 (22%), Positives = 90/226 (39%), Gaps = 14/226 (6%)

Query: 25  SENLVGVISECIERDTSL--CIKEKALKFTERLAFSKDMNIFDGMSLVNIGSA-RSARSY 81
           +  L+ V  EC   +     C+K+KA+ F +RLA    +N+ +G+ LV + +A R   + 
Sbjct: 45  ARTLLRVYDECTRAEAGFVPCLKKKAISFIDRLAPIDAINVAEGIKLVRLETAPRPPATS 104

Query: 82  EPLAED--PKA---RELQLDERIADNMGDFLENHVIQLRLSEPEAESRSLDDEARGXXXX 136
           E   E   P++   R+ +L   + + +  F   H   L++S P+  S  +          
Sbjct: 105 ENELESSLPRSGSDRDAKLTNMLIERLSYFFNGH--SLQVSFPKLTSDEIGRGLEEGRGK 162

Query: 137 XXXXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLN-KNQX 195
                                   G +  +A KA+ + KIA  ++    ++KL++ K+  
Sbjct: 163 MKKMMGMMMMGMAMKMMGMIPIAMGALYILAGKALIISKIALLLAGIIGLKKLMSGKSSG 222

Query: 196 XXXXXXXYAAPHHHEEHPGYSYEPASSGGWGRQA-TDAQSLAYAVH 240
                             G        GGW R++ T+AQ LAY  H
Sbjct: 223 GSSGWSSGGGGGGGGWSSGGG--GGGGGGWDRRSLTEAQELAYRAH 266


>AE014297-425|AAF51897.2|  295|Drosophila melanogaster CG1154-PA
           protein.
          Length = 295

 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 51/226 (22%), Positives = 90/226 (39%), Gaps = 14/226 (6%)

Query: 25  SENLVGVISECIERDTSL--CIKEKALKFTERLAFSKDMNIFDGMSLVNIGSA-RSARSY 81
           +  L+ V  EC   +     C+K+KA+ F +RLA    +N+ +G+ LV + +A R   + 
Sbjct: 45  ARTLLRVYDECTRAEAGFVPCLKKKAISFIDRLAPIDAINVAEGIKLVRLETAPRPPATS 104

Query: 82  EPLAED--PKA---RELQLDERIADNMGDFLENHVIQLRLSEPEAESRSLDDEARGXXXX 136
           E   E   P++   R+ +L   + + +  F   H   L++S P+  S  +          
Sbjct: 105 ENELESSLPRSGSDRDAKLTNMLIERLSYFFNGH--SLQVSFPKLTSDEIGRGLEEGRGK 162

Query: 137 XXXXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLN-KNQX 195
                                   G +  +A KA+ + KIA  ++    ++KL++ K+  
Sbjct: 163 MKKMMGMMMMGMAMKMMGMIPIAMGALYILAGKALIISKIALLLAGIIGLKKLMSGKSSG 222

Query: 196 XXXXXXXYAAPHHHEEHPGYSYEPASSGGWGRQA-TDAQSLAYAVH 240
                             G        GGW R++ T+AQ LAY  H
Sbjct: 223 GSSGWSSGGGGGGGGWSSGGG--GGGGGGWDRRSLTEAQELAYRAH 266


>AE014297-420|AAF51901.1|  274|Drosophila melanogaster CG15591-PA
           protein.
          Length = 274

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 40/171 (23%), Positives = 76/171 (44%), Gaps = 17/171 (9%)

Query: 31  VISECIERDTSLCIKEKALKFTERLAFS-KDMNIFDGMSLVNIGSARSARSYEPLAE-DP 88
           +  +C   + S+C+K K L   E+   S K +++ +G+  V+ G         P++E D 
Sbjct: 64  IYQQCSGDNMSVCLKVKLLTGLEKAFRSAKSLSLMEGIQFVSSGGESEETKRAPISEKDI 123

Query: 89  KA---RELQLDERIADNM-----GDFLENHVIQLRLSEPEAESRSLDDEARGXXXXXXXX 140
           +A   R +   E++ +NM     G+FL++H +Q++  + EA S        G        
Sbjct: 124 EAVLPRSVDAKEQVLNNMILKRVGNFLQDHTLQVKF-DNEANS------VEGRKKKEKKG 176

Query: 141 XXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLLN 191
                               G +A +A KA+ + K+A  +++   I+KLL+
Sbjct: 177 NGAMIMIPLLLGGTIVPLAYGALAMLAGKALIVSKLALVLASIIGIKKLLS 227


>AE014297-432|AAN13237.1|  278|Drosophila melanogaster CG31561-PA
           protein.
          Length = 278

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 54/236 (22%), Positives = 91/236 (38%), Gaps = 19/236 (8%)

Query: 24  ISENLVGVISECIERDTS-LCIKEKALKFTERLAFSKDMNIFDGMSLVNIGSARSARSYE 82
           I +    ++S C     S +C+K + +K  E+LA  +++N+  G+S+V   +A   ++ E
Sbjct: 43  IPQRAESLLSGCEASSFSWMCLKIEFVKIMEKLAEQEELNVLPGISVVKDENATELKTSE 102

Query: 83  PLAE----DPKARELQLDERIADNMGDFLENHVIQLRLSEPEAESRSLDDEARGXXXXXX 138
            +AE     P     +L+  I   + + L    ++ RL     + +SL  E R       
Sbjct: 103 LMAEVARSYPSDPSTRLNGYIVAKLENLLRTRFLRFRL----LDDKSL-VEGRKHKFGKK 157

Query: 139 XXXXXXXXXXXXXXXXXXXXXXGIIAFVAVKAVFLGKIAFAMSAFQLIRKLL----NKNQ 194
                                 G IA +A KA+    +A  +S    ++ L         
Sbjct: 158 GGLEALVAAGVMMKGMLMAMGLGAIALMAGKALMTALMALTLSGVLGLKSLAGGGGKSTT 217

Query: 195 XXXXXXXXYAAPHHH---EEHPGYSYEP--ASSGGWGRQATDAQSLAYAVHLVFDQ 245
                   Y + H H    E  G+S+ P  A+ GG G  A+      YA  L  DQ
Sbjct: 218 YEIVAKPIYTSSHSHSVTHEDGGHSHSPHFAAGGGGGGTASGFGYGGYARSLKVDQ 273


>AF132170-1|AAD34758.1|  286|Drosophila melanogaster unknown
           protein.
          Length = 286

 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/131 (19%), Positives = 57/131 (43%), Gaps = 9/131 (6%)

Query: 7   LLALTASVQCNPLKENSISENLVGVISECIERDTSLCIKEKALKFTERLAFSKDMNIFDG 66
           +L L A +  +P+K    +E   G  ++C+E D+  C++    +  + +  +  + +F G
Sbjct: 10  ILLLAAGISADPVKA---AEEQPGAFAQCLESDSISCLQLTLFRKAKSVFDNPQIELFGG 66

Query: 67  MSLVNIGSARSARSYE-----PLAEDPKARELQLDERIADNMGDFLENHVIQLRLSE-PE 120
           +SLV     R  +S +       A   +AR  ++     DN   F     +    +    
Sbjct: 67  VSLVKSNEGRQGKSLDNSLAVEAAPTVEARTAEMGNYFMDNAKSFFAERSLNFNFANAAR 126

Query: 121 AESRSLDDEAR 131
           + +R++ D+ +
Sbjct: 127 SVARAIPDDIK 137


>AE014297-418|AAF51903.2|  312|Drosophila melanogaster CG1151-PA
           protein.
          Length = 312

 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/131 (19%), Positives = 57/131 (43%), Gaps = 9/131 (6%)

Query: 7   LLALTASVQCNPLKENSISENLVGVISECIERDTSLCIKEKALKFTERLAFSKDMNIFDG 66
           +L L A +  +P+K    +E   G  ++C+E D+  C++    +  + +  +  + +F G
Sbjct: 36  ILLLAAGISADPVKA---AEEQPGAFAQCLESDSISCLQLTLFRKAKSVFDNPQIELFGG 92

Query: 67  MSLVNIGSARSARSYE-----PLAEDPKARELQLDERIADNMGDFLENHVIQLRLSE-PE 120
           +SLV     R  +S +       A   +AR  ++     DN   F     +    +    
Sbjct: 93  VSLVKSNEGRQGKSLDNSLAVEAAPTVEARTAEMGNYFMDNAKSFFAERSLNFNFANAAR 152

Query: 121 AESRSLDDEAR 131
           + +R++ D+ +
Sbjct: 153 SVARAIPDDIK 163


>AE014134-2062|AAF53094.1|  282|Drosophila melanogaster CG14925-PA
           protein.
          Length = 282

 Score = 30.7 bits (66), Expect = 4.8
 Identities = 30/182 (16%), Positives = 66/182 (36%), Gaps = 5/182 (2%)

Query: 31  VISECIERDTSL-CIKEKALKFTERLAFSKDMNIFDGMSLVNIGSARSARSYEPLAEDPK 89
           V  +C +++  + C+K+KAL    R      + I DG++L     + +      L +  +
Sbjct: 57  VYDDCQDKNDFIGCLKQKALHALSRALDQDSIKIVDGLALEKQNQSETESILGSLTDARQ 116

Query: 90  ARELQ-LDERIADNMGDFLENHVIQLRLSEPEAESRSLDDEARGXXXXXXXXXXXXXXXX 148
              L  +D  +       +  H +++ +     E  S+  E                   
Sbjct: 117 FGNLSPIDRALLSKADKLMRTHTLKIDMDVGGGED-SVGREHGHKKKKHKEGGHIKYVVA 175

Query: 149 XXXXXXXXXXXXGI--IAFVAVKAVFLGKIAFAMSAFQLIRKLLNKNQXXXXXXXXYAAP 206
                       G+  +A +A KA+ + K+A  ++    ++KL + +         +A  
Sbjct: 176 ALLTAMGIAGPLGLKALAAIAGKALVISKVALTIAGIIALKKLFSHDHSEETSFQVHAGE 235

Query: 207 HH 208
           H+
Sbjct: 236 HN 237


>AE014297-4594|AAF57047.2|  250|Drosophila melanogaster CG15538-PA
           protein.
          Length = 250

 Score = 30.3 bits (65), Expect = 6.4
 Identities = 17/76 (22%), Positives = 39/76 (51%), Gaps = 1/76 (1%)

Query: 43  CIKEKALKFTERLAFSKDMNIFDGMSLVNIGSARSARSYEPLAEDPKARELQLDERIADN 102
           C + ++L   E +  S +++I+DG+ LV   ++ +  +  P  E    + L   +++A +
Sbjct: 57  CFRSRSLHIFEGIMSSPEISIYDGVRLVAAPNS-TDNATRPDDERKDLKHLTWFDQLAVS 115

Query: 103 MGDFLENHVIQLRLSE 118
           +   L  H +Q+ L +
Sbjct: 116 LAKGLTTHTLQVNLGK 131


>AE014296-852|AAF47904.2|  242|Drosophila melanogaster CG11345-PA
           protein.
          Length = 242

 Score = 30.3 bits (65), Expect = 6.4
 Identities = 9/15 (60%), Positives = 12/15 (80%)

Query: 207 HHHEEHPGYSYEPAS 221
           H H +HPGY+Y+P S
Sbjct: 27  HDHHDHPGYNYDPPS 41


>AY119041-1|AAM50901.1|  393|Drosophila melanogaster LP06455p
           protein.
          Length = 393

 Score = 29.9 bits (64), Expect = 8.4
 Identities = 12/29 (41%), Positives = 21/29 (72%)

Query: 163 IAFVAVKAVFLGKIAFAMSAFQLIRKLLN 191
           +  + +KA+ L KIAF ++A  LI+KL++
Sbjct: 236 VGLLTLKALILSKIAFVVAAIVLIKKLMD 264


>AE014297-416|AAF51905.3|  393|Drosophila melanogaster CG10303-PA
           protein.
          Length = 393

 Score = 29.9 bits (64), Expect = 8.4
 Identities = 12/29 (41%), Positives = 21/29 (72%)

Query: 163 IAFVAVKAVFLGKIAFAMSAFQLIRKLLN 191
           +  + +KA+ L KIAF ++A  LI+KL++
Sbjct: 236 VGLLTLKALILSKIAFVVAAIVLIKKLMD 264


  Database: fruitfly
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 24,830,863
  Number of sequences in database:  52,641
  
Lambda     K      H
   0.316    0.132    0.381 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 17,038,604
Number of Sequences: 52641
Number of extensions: 575389
Number of successful extensions: 1983
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1955
Number of HSP's gapped (non-prelim): 22
length of query: 497
length of database: 24,830,863
effective HSP length: 88
effective length of query: 409
effective length of database: 20,198,455
effective search space: 8261168095
effective search space used: 8261168095
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 64 (29.9 bits)

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